Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NRIP1 ZNF383 ZNF527 ZSCAN12 MSC ZNF628 ZNF570 ZNF175 ZNF780B ZNF507 ZNF571 CHD2 ZNF224 ZNF519 RFX7 ZNF784 ZNF883 ZNF16 ZNF18 FOXD3 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZNF347 ZNF667 ZNF611 ZNF808 NR1H2 ZNF470 ZNF84 ZNF860 ZNF723 ZNF782 SNAPC4 ZBTB11 ZNF160 ZNF454 FOXD1 ZNF572 FOXJ1	3.25e-17	1244	155	43	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	NRIP1 ZNF383 ZNF527 ZSCAN12 MSC ZNF628 ZNF570 ZNF175 ZNF780B ZNF507 ZNF571 CHD2 ZNF224 ZNF519 RFX7 ZNF784 ZNF883 ZNF16 ZNF18 FOXD3 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZNF347 ZNF667 ZNF611 ZNF808 NR1H2 ZNF470 ZNF84 ZNF860 ZNF723 ZNF782 SNAPC4 ZBTB11 ZNF160 ZNF454 FOXD1 ZNF572 FOXJ1	7.10e-17	1271	155	43	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NRIP1 ZNF383 ZNF527 ZSCAN12 MSC ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 CHD2 ZNF224 ZNF519 RFX7 ZNF784 ZNF883 ZNF16 ZNF18 FOXD3 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZNF347 ZNF667 ZNF611 ZNF808 NR1H2 ZNF470 ZNF84 ZNF860 ZNF723 ZNF782 SNAPC4 ZBTB11 ZNF160 ZNF454 FOXD1 ZNF572 FOXJ1	1.90e-15	1459	155	44	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF383 ZNF527 ZSCAN12 MSC ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF224 ZNF519 RFX7 ZNF784 ZNF883 ZNF16 ZNF18 FOXD3 ZNF594 ZNF713 GZF1 ZNF394 ZNF665 ZNF347 ZNF611 ZNF808 NR1H2 ZNF470 ZNF84 ZNF860 ZNF723 ZNF782 ZBTB11 ZNF160 ZNF454 ZHX1 FOXG1 FOXD1 ZNF572 FOXJ1	7.95e-14	1412	155	41	GO:0000981
GeneOntologyMolecularFunction	acetyl-CoA carboxylase activity	ACACA ACACB	5.99e-05	2	155	2	GO:0003989
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF628 ZNF175 ZNF780B ZNF224 ZNF519 ZNF784 ZNF594 GZF1 ZNF808 NR1H2 ZNF782 FOXD1 FOXJ1	4.37e-04	560	155	13	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF628 ZNF175 ZNF780B ZNF224 ZNF519 ZNF784 ZNF594 GZF1 ZNF808 NR1H2 ZNF782 FOXD1 FOXJ1	4.83e-04	566	155	13	GO:0001216
GeneOntologyMolecularFunction	CoA carboxylase activity	ACACA ACACB	8.80e-04	6	155	2	GO:0016421
GeneOntologyMolecularFunction	biotin binding	ACACA ACACB	8.80e-04	6	155	2	GO:0009374
Domain	zf-C2H2	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZNF687 ZNF572	9.88e-19	693	149	35	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZNF687 ZNF572	1.03e-18	694	149	35	IPR013087
Domain	Znf_C2H2-like	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF385B ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZHX1 ZNF687 ZNF572	1.31e-18	796	149	37	IPR015880
Domain	Znf_C2H2	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF385B ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZHX1 ZNF687 ZNF572	1.90e-18	805	149	37	IPR007087
Domain	ZnF_C2H2	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF385B ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZHX1 ZNF687 ZNF572	2.15e-18	808	149	37	SM00355
Domain	ZINC_FINGER_C2H2_2	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZHX1 ZNF687 ZNF572	4.30e-18	775	149	36	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZHX1 ZNF687 ZNF572	4.67e-18	777	149	36	PS00028
Domain	-	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZNF572	3.58e-17	679	149	33	3.30.160.60
Domain	KRAB	ZNF383 ZNF527 ZNF570 ZNF875 ZNF175 ZNF780B ZNF571 ZNF224 ZNF519 ZNF18 ZNF713 ZNF394 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZNF160 ZNF454	1.07e-13	358	149	22	PS50805
Domain	KRAB	ZNF383 ZNF527 ZNF570 ZNF875 ZNF175 ZNF780B ZNF571 ZNF224 ZNF519 ZNF18 ZNF713 ZNF394 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZNF160 ZNF454	1.07e-13	358	149	22	PF01352
Domain	KRAB	ZNF383 ZNF527 ZNF570 ZNF875 ZNF175 ZNF780B ZNF571 ZNF224 ZNF519 ZNF18 ZNF713 ZNF394 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZNF160 ZNF454	1.97e-13	369	149	22	SM00349
Domain	KRAB	ZNF383 ZNF527 ZNF570 ZNF875 ZNF175 ZNF780B ZNF571 ZNF224 ZNF519 ZNF18 ZNF713 ZNF394 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZNF160 ZNF454	2.08e-13	370	149	22	IPR001909
Domain	zf-C2H2_6	ZNF527 ZNF570 ZNF780B ZNF571 ZNF224 ZNF883 ZNF16 GZF1 ZNF660 ZFP64 ZNF667 ZNF611 ZNF808 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF572	7.58e-12	314	149	19	PF13912
Domain	ACC_central	ACACA ACACB	6.32e-05	2	149	2	PF08326
Domain	AcCoA_COase_cen	ACACA ACACB	6.32e-05	2	149	2	IPR013537
Domain	Disintegrin_dom	ADAMTS3 ADAMTS1 ADAM18 DUSP10	3.13e-04	41	149	4	IPR001762
Domain	ATP_grasp_subdomain_1	TTLL3 ACACA ACACB	3.72e-04	18	149	3	IPR013815
Domain	Carboxyl_trans	ACACA ACACB	3.75e-04	4	149	2	PF01039
Domain	COA_CT_CTER	ACACA ACACB	3.75e-04	4	149	2	PS50989
Domain	COA_CT_NTER	ACACA ACACB	3.75e-04	4	149	2	PS50980
Domain	COA_CT_N	ACACA ACACB	3.75e-04	4	149	2	IPR011762
Domain	COA_CT_C	ACACA ACACB	3.75e-04	4	149	2	IPR011763
Domain	Carboxyl_trans	ACACA ACACB	3.75e-04	4	149	2	IPR000022
Domain	TF_fork_head_CS_2	FOXD3 FOXG1 FOXD1 FOXJ1	4.89e-04	46	149	4	IPR030456
Domain	TF_fork_head_CS_1	FOXD3 FOXG1 FOXD1 FOXJ1	5.32e-04	47	149	4	IPR018122
Domain	Biotin_BS	ACACA ACACB	6.22e-04	5	149	2	IPR001882
Domain	Myosin_S1_N	MYO5A MYO5B	6.22e-04	5	149	2	IPR008989
Domain	Biotin_COase_C	ACACA ACACB	6.22e-04	5	149	2	IPR005482
Domain	BC	ACACA ACACB	6.22e-04	5	149	2	PS50979
Domain	Biotin_carb_C	ACACA ACACB	6.22e-04	5	149	2	SM00878
Domain	Biotin_carb_C	ACACA ACACB	6.22e-04	5	149	2	PF02785
Domain	Biotin_carboxylation_dom	ACACA ACACB	6.22e-04	5	149	2	IPR011764
Domain	CPSASE_1	ACACA ACACB	6.22e-04	5	149	2	PS00866
Domain	BIOTIN	ACACA ACACB	6.22e-04	5	149	2	PS00188
Domain	FH	FOXD3 FOXG1 FOXD1 FOXJ1	6.24e-04	49	149	4	SM00339
Domain	FORK_HEAD_1	FOXD3 FOXG1 FOXD1 FOXJ1	6.24e-04	49	149	4	PS00657
Domain	FORK_HEAD_2	FOXD3 FOXG1 FOXD1 FOXJ1	6.24e-04	49	149	4	PS00658
Domain	Fork_head_dom	FOXD3 FOXG1 FOXD1 FOXJ1	6.24e-04	49	149	4	IPR001766
Domain	FORK_HEAD_3	FOXD3 FOXG1 FOXD1 FOXJ1	6.24e-04	49	149	4	PS50039
Domain	Forkhead	FOXD3 FOXG1 FOXD1 FOXJ1	6.24e-04	49	149	4	PF00250
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL1 ADAMTS3 ADAMTS1	8.91e-04	24	149	3	IPR013273
Domain	-	EVPL DST	9.29e-04	6	149	2	3.90.1290.10
Domain	Dilute_dom	MYO5A MYO5B	9.29e-04	6	149	2	IPR002710
Domain	Rudment_hybrid_motif	ACACA ACACB	9.29e-04	6	149	2	IPR011054
Domain	DUF3398	DOCK11 DOCK9	9.29e-04	6	149	2	PF11878
Domain	DIL	MYO5A MYO5B	9.29e-04	6	149	2	PF01843
Domain	CPSASE_2	ACACA ACACB	9.29e-04	6	149	2	PS00867
Domain	DILUTE	MYO5A MYO5B	9.29e-04	6	149	2	PS51126
Domain	DOCK_C/D_N	DOCK11 DOCK9	9.29e-04	6	149	2	IPR021816
Domain	DIL	MYO5A MYO5B	9.29e-04	6	149	2	SM01132
Domain	Plectin	EVPL DST	1.29e-03	7	149	2	PF00681
Domain	CbamoylP_synth_lsu-like_ATP-bd	ACACA ACACB	1.29e-03	7	149	2	IPR005479
Domain	BC-like_N	ACACA ACACB	1.29e-03	7	149	2	IPR005481
Domain	Plectin_repeat	EVPL DST	1.29e-03	7	149	2	IPR001101
Domain	CPSase_L_D2	ACACA ACACB	1.29e-03	7	149	2	PF02786
Domain	Biotin_carb_N	ACACA ACACB	1.29e-03	7	149	2	PF00289
Domain	PLEC	EVPL DST	1.29e-03	7	149	2	SM00250
Domain	Spectrin_repeat	DRP2 EVPL DST	1.56e-03	29	149	3	IPR002017
Domain	ATP_grasp_subdomain_2	TTLL3 ACACA ACACB	1.90e-03	31	149	3	IPR013816
Domain	SPEC	DRP2 EVPL DST	2.08e-03	32	149	3	SM00150
Domain	Spectrin/alpha-actinin	DRP2 EVPL DST	2.08e-03	32	149	3	IPR018159
Domain	ASC	ASIC5 SCNN1D	2.19e-03	9	149	2	PF00858
Domain	ASC	ASIC5 SCNN1D	2.19e-03	9	149	2	PS01206
Domain	Na+channel_ASC	ASIC5 SCNN1D	2.19e-03	9	149	2	IPR001873
Domain	Biotin_lipoyl	ACACA ACACB	2.19e-03	9	149	2	PF00364
Domain	zf-C2H2_11	ZNF667 ZNF687	2.19e-03	9	149	2	PF16622
Domain	BIOTINYL_LIPOYL	ACACA ACACB	2.73e-03	10	149	2	PS50968
Domain	Biotin_lipoyl	ACACA ACACB	2.73e-03	10	149	2	IPR000089
Domain	DHR-1_domain	DOCK11 DOCK9	3.32e-03	11	149	2	IPR027007
Domain	DHR_2	DOCK11 DOCK9	3.32e-03	11	149	2	PS51651
Domain	DHR_1	DOCK11 DOCK9	3.32e-03	11	149	2	PS51650
Domain	DHR-2	DOCK11 DOCK9	3.32e-03	11	149	2	PF06920
Domain	DOCK	DOCK11 DOCK9	3.32e-03	11	149	2	IPR026791
Domain	DOCK_C	DOCK11 DOCK9	3.32e-03	11	149	2	IPR010703
Domain	DOCK-C2	DOCK11 DOCK9	3.32e-03	11	149	2	PF14429
Domain	DHR-2	DOCK11 DOCK9	3.32e-03	11	149	2	IPR027357
Domain	Pep_M12B_propep	ADAMTS3 ADAMTS1 ADAM18	3.69e-03	39	149	3	PF01562
Domain	Peptidase_M12B_N	ADAMTS3 ADAMTS1 ADAM18	3.69e-03	39	149	3	IPR002870
Domain	Single_hybrid_motif	ACACA ACACB	3.96e-03	12	149	2	IPR011053
Domain	DISINTEGRIN_1	ADAMTS3 ADAMTS1 ADAM18	3.96e-03	40	149	3	PS00427
Domain	Reprolysin	ADAMTS3 ADAMTS1 ADAM18	3.96e-03	40	149	3	PF01421
Domain	ADAM_MEPRO	ADAMTS3 ADAMTS1 ADAM18	3.96e-03	40	149	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS3 ADAMTS1 ADAM18	3.96e-03	40	149	3	PS50214
Domain	Peptidase_M12B	ADAMTS3 ADAMTS1 ADAM18	3.96e-03	40	149	3	IPR001590
Domain	Lectin_C	ATRN MRC1 PKD1L3 CD93	4.58e-03	84	149	4	PF00059
Domain	-	ACACA ACACB	4.65e-03	13	149	2	3.40.50.20
Domain	NCD3G	GPRC6A GRM3	4.65e-03	13	149	2	PF07562
Domain	GPCR_3_9-Cys_dom	GPRC6A GRM3	4.65e-03	13	149	2	IPR011500
Domain	-	MRC1 IGF2R	4.65e-03	13	149	2	2.10.10.10
Domain	C-type_lectin-like	ATRN MRC1 PKD1L3 CD93	4.98e-03	86	149	4	IPR001304
Domain	F-box-like	FBXO39 FBXL2 FBXW7	5.19e-03	44	149	3	PF12937
Domain	FN_type2_col-bd	MRC1 IGF2R	5.40e-03	14	149	2	IPR000562
Domain	FN2_2	MRC1 IGF2R	5.40e-03	14	149	2	PS51092
Domain	FN2_1	MRC1 IGF2R	5.40e-03	14	149	2	PS00023
Domain	ATP_GRASP	ACACA ACACB	5.40e-03	14	149	2	PS50975
Domain	ATP-grasp	ACACA ACACB	5.40e-03	14	149	2	IPR011761
Domain	PreATP-grasp_dom	ACACA ACACB	5.40e-03	14	149	2	IPR016185
Domain	fn2	MRC1 IGF2R	5.40e-03	14	149	2	PF00040
Domain	GPCR_3_CS	GPRC6A GRM3	5.40e-03	14	149	2	IPR017979
Domain	FN2	MRC1 IGF2R	5.40e-03	14	149	2	SM00059
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF383 ZNF570 ZNF875 ZNF175 ZNF571 ZNF224 ZNF519 ATAD2 CDC7 ZNF18 ZNF713 ZNF394 ZNF660 ABCA6 ZNF665 ZNF347 ZNF667 ZNF611 NR1H2 ZNF470 ZNF860 ZNF782 SNAPC4 ZNF160 ZNF454 FOXG1	2.24e-06	1387	99	26	M734
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS	ZNF665 ZNF347 ZNF782 ZNF160 ZNF454	4.44e-05	56	99	5	MM17236
Pubmed	Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.	FOXD3 FOXG1 FOXD1 FOXJ1	1.35e-07	11	159	4	7683413
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZSCAN12 ZNF175 ZC3H13 ZNF507 ATAD2 ZNF18 ZNF394 ZC2HC1A ZNF665 ZFP64 ZNF347 NR1H2 SNAPC4 ZNF160 ZNF687	5.00e-06	808	159	15	20412781
Pubmed	Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.	MSC ZNF665 ZNF347 ZNF160 FOXG1	8.36e-06	60	159	5	18023262
Pubmed	Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.	FOXD3 FOXG1 FOXD1 FOXJ1	9.14e-06	29	159	4	7789972
Pubmed	Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.	ACACA ACACB	2.08e-05	2	159	2	24944901
Pubmed	Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.	ACACA ACACB	2.08e-05	2	159	2	20139635
Pubmed	Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.	ACACA ACACB	2.08e-05	2	159	2	28081256
Pubmed	Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.	ACACA ACACB	2.08e-05	2	159	2	26976583
Pubmed	AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation.	ACACA ACACB	2.08e-05	2	159	2	25001074
Pubmed	The subcellular localization of acetyl-CoA carboxylase 2.	ACACA ACACB	2.08e-05	2	159	2	10677481
Pubmed	Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.	ACACA ACACB	2.08e-05	2	159	2	24338821
Pubmed	De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.	ACACA ACACB	2.08e-05	2	159	2	25282359
Pubmed	Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.	ACACA ACACB	2.08e-05	2	159	2	27693630
Pubmed	Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.	ACACA ACACB	2.08e-05	2	159	2	32215608
Pubmed	Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor.	ACACA ACACB	2.08e-05	2	159	2	29772612
Pubmed	Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.	ACACA ACACB	2.08e-05	2	159	2	29976587
Pubmed	Structure and regulation of acetyl-CoA carboxylase genes of metazoa.	ACACA ACACB	2.08e-05	2	159	2	15749055
Pubmed	Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia.	MYO5A TF	2.08e-05	2	159	2	3681112
Pubmed	Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina.	FOXG1 FOXD1	2.08e-05	2	159	2	7815060
Pubmed	AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis.	ACACA ACACB	2.08e-05	2	159	2	29433631
Pubmed	Exome sequencing: an efficient diagnostic tool for complex neurodegenerative disorders.	APOB SACS	2.08e-05	2	159	2	23043354
Pubmed	Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin.	ACACA ACACB	2.08e-05	2	159	2	36076520
Pubmed	Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.	ACACA ACACB	2.08e-05	2	159	2	28290443
Pubmed	Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.	ACACA ACACB	2.08e-05	2	159	2	30244972
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA2D1 ZSCAN12 MYO5A DOCK11 PKP4 KSR2 GRM3 CACNG2 IGF2R DST NF1 ZNF394 ZC2HC1A AKAP9 FOXG1	3.87e-05	963	159	15	28671696
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ACACA MYO5A ZC3H13 USP24 CHD2 ATAD2 IGF2R DST NF1 HELZ ASCC3 ZBTB11	5.04e-05	653	159	12	22586326
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	ACACA USP24 PJA2 DST SLMAP HELZ PIPSL	5.77e-05	212	159	7	33853758
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ACACA ZC3H13 USP24 ZNF507 ZNF224 RFX7 ATAD2 NF1 PTPRC HELZ SNAPC4 ZHX1 ZNF687	6.10e-05	774	159	13	15302935
Pubmed	C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme.	APOB NF1	6.21e-05	3	159	2	11727199
Pubmed	AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue.	ACACA ACACB	6.21e-05	3	159	2	34668531
Pubmed	AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.	ACACA ACACB	6.21e-05	3	159	2	30018077
Pubmed	Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4.	MRC1 PTPRC	6.21e-05	3	159	2	27601670
Pubmed	Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.	MYO5A MYO5B	6.21e-05	3	159	2	28939769
Pubmed	Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels.	ACACA ACACB	6.21e-05	3	159	2	19846279
Pubmed	Exploring genetic variations that may be associated with the direct effects of some antipsychotics on lipid levels.	ACACA ACACB	6.21e-05	3	159	2	18031993
Pubmed	Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.	MYO5A MYO5B	6.21e-05	3	159	2	24508725
Pubmed	Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis.	ACACA ACACB	6.21e-05	3	159	2	20457939
Pubmed	Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.	MYO5A MYO5B	6.21e-05	3	159	2	24339992
Pubmed	Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism.	ACACA ACACB	6.21e-05	3	159	2	36417534
Pubmed	Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.	ACACA ACACB	6.21e-05	3	159	2	18455495
Pubmed	Coordination of NF-kappaB and NFAT antagonism by the forkhead transcription factor Foxd1.	FOXD1 FOXJ1	6.21e-05	3	159	2	16585573
Pubmed	Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.	DOCK11 DOCK9	6.21e-05	3	159	2	32241915
Pubmed	The temporal and spatial expression pattern of myosin Va, Vb and VI in the mouse ovary.	MYO5A MYO5B	6.21e-05	3	159	2	16713372
Pubmed	Prediction of the metabolic syndrome status based on dietary and genetic parameters, using Random Forest.	ACACB APOB	6.21e-05	3	159	2	19034549
Pubmed	YY1 and FoxD3 regulate antiretroviral zinc finger protein OTK18 promoter activation induced by HIV-1 infection.	ZNF175 FOXD3	6.21e-05	3	159	2	19034670
Pubmed	LINKAGE OF THE MOUSE TRANSFERRIN LOCUS.	MYO5A TF	6.21e-05	3	159	2	14051864
Pubmed	Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.	ACACA ACACB	6.21e-05	3	159	2	28877461
Pubmed	Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas.	ACACA ACACB	6.21e-05	3	159	2	17521700
Pubmed	Structural insights into functional overlapping and differentiation among myosin V motors.	MYO5A MYO5B	6.21e-05	3	159	2	24097982
Pubmed	Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis.	ACACA ACACB	6.21e-05	3	159	2	31990961
Pubmed	The Regulation of Frontal Cortex Cholesterol Metabolism Abnormalities by NR3C1/NRIP1/NR1H2 Is Involved in the Occurrence of Stress-Induced Depression.	NRIP1 NR1H2	6.21e-05	3	159	2	39125645
Pubmed	The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels.	ACACA ACACB	6.21e-05	3	159	2	27381369
Pubmed	Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice.	ACACA ACACB	6.21e-05	3	159	2	17210641
Pubmed	Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.	ACACA ACACB	6.21e-05	3	159	2	28768177
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF175 ZNF665 ZNF347 ZNF160	7.59e-05	49	159	4	9630514
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	CACNA2D1 TTLL3 DIS3L RAPGEF5 ZNF570 ZNF571 EVPL CDK14 ATAD2 PJA2 DST NF1 ZFAND6 HELZ DUSP10 POLQ PRIMPOL	9.53e-05	1293	159	17	15342556
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NRIP1 GNL3L ACACA ACACB DOCK11 DOCK9 CHD2 XIRP2 ASCC3 ZNF687	1.04e-04	497	159	10	36774506
Pubmed	Assignment of the human helix-loop-helix transcription factor gene musculin/activated B-cell factor-1 (MSC) to chromosome 8q21 and its mouse homologue (Msc) to the proximal region of chromosome 1.	MSC DST	1.24e-04	4	159	2	10198176
Pubmed	Location of the gene for Theta antigen in the mouse.	MYO5A TF	1.24e-04	4	159	2	4566335
Pubmed	Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.	ACACA ACACB	1.24e-04	4	159	2	24185692
Pubmed	MIG12 is involved in the LXR activation-mediated induction of the polymerization of mammalian acetyl-CoA carboxylase.	ACACA NR1H2	1.24e-04	4	159	2	34153683
Pubmed	Three novel spermatogenesis-specific zinc finger genes.	ZSCAN12 ZNF394	1.24e-04	4	159	2	12860387
Pubmed	Crystal structure of Spot 14, a modulator of fatty acid synthesis.	ACACA ACACB	1.24e-04	4	159	2	20952656
Pubmed	A hereditary model of slowly progressive polycystic kidney disease in the mouse.	MYO5A TF	1.24e-04	4	159	2	1883968
Pubmed	Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.	ACACA ACACB	1.24e-04	4	159	2	38447582
Pubmed	Structural basis of myosin V Rab GTPase-dependent cargo recognition.	MYO5A MYO5B	1.24e-04	4	159	2	24248336
Pubmed	Alternative splicing in class V myosins determines association with Rab10.	MYO5A MYO5B	1.24e-04	4	159	2	19008234
Pubmed	Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions.	APOB PTPRC	1.24e-04	4	159	2	22144566
Pubmed	The bcl-2 family member, Bcl2a1, maps to mouse chromosome 9 and human chromosome 15.	MYO5A TF	1.24e-04	4	159	2	9096119
Pubmed	Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype.	NRIP1 NR1H2	1.24e-04	4	159	2	18195045
Pubmed	ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.	ADAMTS3 ADAMTS1	1.24e-04	4	159	2	10094461
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NRIP1 ACACA ACACB USP24 ZNF507 DST ASCC3 ZBTB11 ZNF687	1.40e-04	418	159	9	34709266
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATRN NRIP1 GNL3L TTLL3 ACACA MID2 MYO5A ZNF875 KSR2 CHD2 ZNF385B COG3 TECTA CDK14 TTC8 ZFP64 AKAP13 ZNF84	1.68e-04	1489	159	18	28611215
Pubmed	Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.	DOCK9 PKP4 LRRC3B JOSD1	1.68e-04	60	159	4	22889411
Pubmed	Foxg1 regulates retinal axon pathfinding by repressing an ipsilateral program in nasal retina and by causing optic chiasm cells to exert a net axonal growth-promoting activity.	FOXG1 FOXD1	2.06e-04	5	159	2	19004857
Pubmed	Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals.	NRIP1 DUSP10	2.06e-04	5	159	2	24975273
Pubmed	Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss.	ACACA ACACB	2.06e-04	5	159	2	32694673
Pubmed	Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.	ACACA ACACB	2.06e-04	5	159	2	37163372
Pubmed	[ADAMTS family--new extracellular matrix degrading enzyme].	ADAMTS3 ADAMTS1	2.06e-04	5	159	2	11831030
Pubmed	A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).	NF1 FBXW7	2.06e-04	5	159	2	21642990
Pubmed	Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.	DOCK11 DOCK9	2.06e-04	5	159	2	15710388
Pubmed	Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor.	IGF2R AP1G1	2.06e-04	5	159	2	11387476
Pubmed	TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.	ACACA ACACB	2.06e-04	5	159	2	16794074
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	ACACB DOCK11 PKP4 RALGPS2 DST NF1 AKAP9 SLMAP HELZ	2.26e-04	446	159	9	24255178
Pubmed	Identification of differentially expressed genes in mouse spermatogenesis.	ZNF665 ZNF347 ZNF160	2.53e-04	27	159	3	14581517
Pubmed	Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue.	PKD1L3 SCNN1D	3.08e-04	6	159	2	19812697
Pubmed	Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.	MRC1 IGF2R	3.08e-04	6	159	2	32234475
Pubmed	Pax6 is required for establishing naso-temporal and dorsal characteristics of the optic vesicle.	FOXG1 FOXD1	3.08e-04	6	159	2	12223410
Pubmed	Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins.	CD93 PTPRC	3.08e-04	6	159	2	21768350
Pubmed	The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.	DOCK11 DOCK9	3.08e-04	6	159	2	25851601
Pubmed	Dorsal-ventral patterning defects in the eye of BF-1-deficient mice associated with a restricted loss of shh expression.	FOXG1 FOXD1	3.08e-04	6	159	2	10373304
Pubmed	Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.	MYO5A MYO5B	3.08e-04	6	159	2	25673849
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF224 ZNF16 ZNF18	3.84e-04	31	159	3	2288909
Pubmed	Chromosomal localization of mouse bullous pemphigoid antigens. BPAG1 and BPAG2: identification of a new region of homology between mouse and human chromosomes.	CHRNG DST	4.30e-04	7	159	2	8432531
Pubmed	Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter.	FOXD3 FOXJ1	4.30e-04	7	159	2	7958446
Pubmed	HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.	CACNA2D1 ZNF594 ZNF394	5.06e-04	34	159	3	25925205
Pubmed	LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.	ACACA ACACB KCNJ11	5.06e-04	34	159	3	26378152
Pubmed	Transcription factor Foxd1 is required for the specification of the temporal retina in mammals.	FOXG1 FOXD1	5.71e-04	8	159	2	21490208
Pubmed	The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.	TECTA FOXG1	5.71e-04	8	159	2	16141228
Pubmed	The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations.	ACACA ACACB	5.71e-04	8	159	2	36001969
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF383 ZNF527 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF224 ZNF784 ZNF665 ZNF347 ZNF667 ZNF611 ZNF808 NR1H2 ZNF470 ZNF160 VSTM1	6.88e-09	1192	159	20	chr19q13
Cytoband	7q21-q22	CACNA2D1 CDK14 AKAP9	4.81e-06	10	159	3	7q21-q22
Cytoband	19q13.42	ZNF628 ZNF784 ZNF665 ZNF347 ZNF160 VSTM1	5.24e-06	125	159	6	19q13.42
Cytoband	19q13.12	ZNF383 ZNF570 ZNF875 ZNF571	1.19e-04	72	159	4	19q13.12
Cytoband	20p11.21	CST7 CD93 GZF1	2.06e-04	33	159	3	20p11.21
Cytoband	8q24.13	ATAD2 ZHX1 ZNF572	2.68e-04	36	159	3	8q24.13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF383 ZNF527 ZSCAN12 ZNF628 ZNF570 ZNF875 ZNF175 ZNF780B ZNF507 ZNF571 ZNF224 ZNF519 ZNF784 ZNF883 ZNF16 ZNF18 ZNF594 ZNF713 GZF1 ZNF394 ZNF660 ZNF665 ZFP64 ZNF347 ZNF667 ZNF611 ZNF808 ZNF470 ZNF84 ZNF860 ZNF782 ZBTB11 ZNF160 ZNF454 ZHX1 ZNF572	1.68e-21	718	125	36	28
GeneFamily	Myosins, class V	MYO5A MYO5B	1.42e-04	3	125	2	1100
GeneFamily	Forkhead boxes	FOXD3 FOXG1 FOXD1 FOXJ1	2.18e-04	43	125	4	508
GeneFamily	EF-hand domain containing\|Plakins	EVPL DST	1.29e-03	8	125	2	939
Coexpression	NIKOLSKY_BREAST_CANCER_19Q13.1_AMPLICON	ZNF383 ZNF527 ZNF570 ZNF875 ZNF571	1.87e-07	22	159	5	M8692
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZSCAN12 ZNF570 ZNF883 ZNF594 ZNF713 ZNF660 KCNJ11 DCLRE1A VSTM5	3.98e-08	197	159	9	fd76cc5e12c7e7943a48f739e4f0626ff7211f51
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DOCK9 PKP4 CST7 MEIOC AP1G1 SLMAP POLQ	3.24e-06	175	159	7	a3f8c54c77bce9b035a4835945ab341909be4946
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP24 CHD2 IGF2R NF1 PTPRC AP1G1 ZBTB11	5.19e-06	188	159	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Healthy-B_naive\|Healthy / disease group, cell group and cell class	RAPGEF5 KSR2 RALGPS2 CDK14 ABCA6 ZNF667 ZNF860	5.96e-06	192	159	7	5fddf679dcc9c0077d6bfe04c1e602863fb959eb
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DIS3L DOCK9 C4orf50 CST7 ATAD2 TF POLQ	7.05e-06	197	159	7	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	CACNA2D1 MYO5B ZNF571 ZNF385B SLMAP ZNF385C ADGRF1	7.05e-06	197	159	7	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	ZNF883 IGF2R DST ZC2HC1A AKAP9 LRRC3B FOXG1	7.53e-06	199	159	7	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	Healthy-B_cell\|World / disease group, cell group and cell class	DOCK9 RALGPS2 C4orf50 ABCA6 ZNF667 ZNF860	1.43e-05	146	159	6	588359d3df6ad7090b7fa6c7f8d29cc1717e7f4f
Disease	3-(3-amino-3-carboxypropyl)uridine measurement	ATAD2 ZHX1	2.67e-05	2	153	2	EFO_0800632
Disease	fish oil supplement exposure measurement, total cholesterol measurement	USP24 ABCA6	2.67e-05	2	153	2	EFO_0004574, EFO_0600007
Disease	specific language impairment, dyslexia	ZFP64 CCDC136 PMFBP1	2.91e-05	12	153	3	EFO_0005424, EFO_1001510
Disease	Colorectal Carcinoma	TTLL3 ACACA CAPN6 APOB CD93 NF1 AKAP9 ABCA6 LRRC3B SACS FBXL2 ZNF572 FBXW7	7.96e-05	702	153	13	C0009402
Disease	phospholipids in medium LDL measurement	EFCAB13 APOB IGF2R ABCA6	1.23e-04	49	153	4	EFO_0022183
Disease	cholesterol in medium LDL measurement	EFCAB13 APOB IGF2R ABCA6	1.23e-04	49	153	4	EFO_0022224
Disease	phospholipids in very small VLDL measurement	COX19 APOB ABCA6 PMFBP1	1.44e-04	51	153	4	EFO_0022300
Disease	total lipids in medium LDL	EFCAB13 APOB IGF2R ABCA6	1.55e-04	52	153	4	EFO_0022180
Disease	fish oil supplement exposure measurement, low density lipoprotein cholesterol measurement	USP24 ABCA6	1.59e-04	4	153	2	EFO_0004611, EFO_0600007
Disease	apolipoprotein B measurement	CACNA2D1 ACACB EFCAB13 USP24 APOB ZNF224 PKD1L3 IGF2R NF1 AP1G1 ABCA6 PMFBP1	1.86e-04	663	153	12	EFO_0004615
Disease	proprotein convertase subtilisin/kexin type 9 measurement	KSR2 USP24 APOB	1.96e-04	22	153	3	EFO_0009312
Disease	cholesterol in IDL measurement	COX19 EFCAB13 APOB ABCA6	2.37e-04	58	153	4	EFO_0021899
Disease	Brugada Syndrome (disorder)	CACNA2D1 AKAP9 SLMAP	2.55e-04	24	153	3	C1142166
Disease	TOM1-like protein 1 measurement	ZC3H13 CPB2	2.64e-04	5	153	2	EFO_0802136
Disease	muscular disease (implicated_via_orthology)	ACACA ACACB	2.64e-04	5	153	2	DOID:0080000 (implicated_via_orthology)
Disease	free cholesterol in IDL measurement	COX19 EFCAB13 APOB ABCA6	2.88e-04	61	153	4	EFO_0022181
Disease	LDL cholesterol change measurement	APOB PKD1L3	5.51e-04	7	153	2	EFO_0007804
Disease	Obesity	MRC1 ACACB KSR2 CPB2 TF TTC8	7.23e-04	205	153	6	C0028754
Disease	intelligence, specific language impairment, dyslexia	CCDC136 PMFBP1	7.33e-04	8	153	2	EFO_0004337, EFO_0005424, EFO_1001510
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	ACACB USP24 APOB IGF2R ABCA6 CALN1 PMFBP1	8.41e-04	291	153	7	EFO_0008317, EFO_0020946
Disease	carboxypeptidase B2 measurement	ZC3H13 CPB2	1.17e-03	10	153	2	EFO_0008069
Disease	cholesterol in very small VLDL measurement	COX19 APOB ABCA6	1.17e-03	40	153	3	EFO_0022231
Disease	free cholesterol in medium LDL measurement	EFCAB13 APOB ABCA6	1.17e-03	40	153	3	EFO_0022268
Disease	sleep duration, low density lipoprotein cholesterol measurement	USP24 APOB PKD1L3 IGF2R	1.31e-03	91	153	4	EFO_0004611, EFO_0005271
Disease	spontaneous preterm birth, parental genotype effect measurement	CACNA2D1 ARHGAP28	1.42e-03	11	153	2	EFO_0005939, EFO_0006917
Disease	Malignant neoplasm of breast	NRIP1 ADAMTS1 EFCAB13 C4orf50 XDH COG3 TECTA NAA25 NF1 PTPRC AKAP9 LRRC3B ZFP64 FBXW7	1.45e-03	1074	153	14	C0006142
Disease	total lipids in very small VLDL measurement	COX19 APOB ABCA6	1.65e-03	45	153	3	EFO_0022156
Disease	free cholesterol in very small VLDL measurement	COX19 APOB ABCA6	1.88e-03	47	153	3	EFO_0022275
Disease	MAP kinase-activated protein kinase 3 measurement	ZC3H13 CPB2	2.01e-03	13	153	2	EFO_0008226
Disease	xanthine measurement	KSR2 EYS	2.01e-03	13	153	2	EFO_0010548
Disease	homostachydrine measurement	EYS SLC36A3	2.01e-03	13	153	2	EFO_0021164
Disease	cholesterol in small LDL measurement	APOB IGF2R ABCA6	2.11e-03	49	153	3	EFO_0022227
Disease	free cholesterol in LDL measurement	EFCAB13 APOB ABCA6	2.24e-03	50	153	3	EFO_0022266
Disease	cholesteryl ester measurement	COX19 EFCAB13 APOB EYS IGF2R ABCA6	2.29e-03	257	153	6	EFO_0010351
Disease	chronic kidney disease (is_implicated_in)	XDH CPB2	2.33e-03	14	153	2	DOID:784 (is_implicated_in)
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	ADAMTS3 APOB	2.33e-03	14	153	2	EFO_0004611, EFO_0008589
Disease	free cholesterol in large LDL measurement	EFCAB13 APOB ABCA6	2.37e-03	51	153	3	EFO_0022176
Disease	very low density lipoprotein cholesterol measurement	COX19 ACACB APOB IGF2R ABCA6 PMFBP1	2.43e-03	260	153	6	EFO_0008317
Disease	phospholipids in medium VLDL measurement	APOB IGF2R ABCA6	2.51e-03	52	153	3	EFO_0022154
Disease	phospholipids in IDL measurement	COX19 APOB ABCA6	2.51e-03	52	153	3	EFO_0022164
Disease	total lipids in LDL measurement	APOB IGF2R ABCA6	2.51e-03	52	153	3	EFO_0022308
Disease	free cholesterol measurement, chylomicron measurement, very low density lipoprotein cholesterol measurement	ACACB APOB CALN1 PMFBP1	2.62e-03	110	153	4	EFO_0008317, EFO_0008591, EFO_0008596
Disease	phospholipids in large LDL measurement	EFCAB13 APOB ABCA6	2.65e-03	53	153	3	EFO_0022174
Disease	cholesterol in small VLDL measurement	APOB IGF2R ABCA6	2.65e-03	53	153	3	EFO_0022228
Disease	free cholesterol in small LDL measurement	EFCAB13 APOB ABCA6	2.65e-03	53	153	3	EFO_0022271
Disease	Abnormality of refraction	NRIP1 ADAMTSL1 MYO5B KSR2 ZNF571 GRM3 CHRNG TTC8 AKAP13 CALN1	2.77e-03	673	153	10	HP_0000539
Disease	factor XI measurement, coronary artery disease	CNNM2 NAA25 IGF2R ZNF160	3.08e-03	115	153	4	EFO_0001645, EFO_0004694
Disease	total lipids in large LDL	APOB IGF2R ABCA6	3.26e-03	57	153	3	EFO_0022163
Disease	cholesterol in large LDL measurement	APOB IGF2R ABCA6	3.26e-03	57	153	3	EFO_0021901
Disease	refractive error, age at onset, Myopia	NRIP1 ADAMTSL1 MYO5B GRM3 TTC8	3.41e-03	193	153	5	EFO_0004847, HP_0000545, MONDO_0004892
Disease	phospholipids in LDL measurement	EFCAB13 APOB ABCA6	3.42e-03	58	153	3	EFO_0022294
Disease	sucrose measurement	C4orf50 ZFP64	3.45e-03	17	153	2	EFO_0010535
Disease	Familial Progressive Myoclonic Epilepsy	CHD2 SACS	3.45e-03	17	153	2	C0751777
Disease	Atypical Inclusion-Body Disease	CHD2 SACS	3.45e-03	17	153	2	C0751776
Disease	Myoclonic Epilepsies, Progressive	CHD2 SACS	3.45e-03	17	153	2	C0751778
Disease	Biotin-Responsive Encephalopathy	CHD2 SACS	3.45e-03	17	153	2	C0751780
Disease	May-White Syndrome	CHD2 SACS	3.45e-03	17	153	2	C0751782
Disease	Dentatorubral-Pallidoluysian Atrophy	CHD2 SACS	3.45e-03	17	153	2	C0751781
Disease	phospholipids in small LDL measurement	APOB IGF2R ABCA6	3.59e-03	59	153	3	EFO_0022297
Disease	total lipids in IDL	COX19 APOB ABCA6	3.77e-03	60	153	3	EFO_0022161
Disease	Insulin Resistance	MRC1 ACACB KCNJ11	3.77e-03	60	153	3	C0021655
Disease	Insulin Sensitivity	MRC1 ACACB KCNJ11	3.77e-03	60	153	3	C0920563
Disease	level of Sphingomyelin (d34:1) in blood serum	ADAMTS3 USP24	3.87e-03	18	153	2	OBA_2045175
Disease	Action Myoclonus-Renal Failure Syndrome	CHD2 SACS	3.87e-03	18	153	2	C0751779
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ACACB APOB ABCA6 CALN1 PMFBP1	3.96e-03	200	153	5	EFO_0004611, EFO_0020945
Disease	Myopia	NRIP1 ADAMTSL1 MYO5B DOCK9 ZNF385B GRM3 AKAP13	4.07e-03	385	153	7	HP_0000545
Disease	late-onset Alzheimers disease	ADAMTS1 RAPGEF5 ADAM18 KSR2 TECTA SLMAP	4.28e-03	292	153	6	EFO_1001870
Disease	etiocholanolone glucuronide measurement	XDH ZNF394	4.31e-03	19	153	2	EFO_0800362
Disease	serum zinc measurement	ADAMTSL1 C4orf50	4.31e-03	19	153	2	EFO_0005268

Protein segments in the cluster

Peptide	Gene	Start	Entry
SQNVSKADNRQQHSF	PKP4	166	Q99569
CKVTVNSASQLQAHN	ZNF385C	226	Q66K41
NFSRTNASSKHCENR	EPC2	496	Q52LR7
TASSKQAHAVCQQEQ	AKAP9	1471	Q99996
KHGDNQQFLVNTNCA	CXorf65	6	A6NEN9
HLNNLSQSVNFCERT	ADGRF1	136	Q5T601
NLIACARHQQSHFDN	CHRNG	446	P07510
VNSLHERSENCGFKN	ADAM18	521	Q9Y3Q7
EQKFQCSLQNKRNHR	GRM3	356	Q14832
QCGKQFTQLNALQRH	GZF1	551	Q9H116
NSSSCFQHQRTNAKV	ABCA6	436	Q8N139
FDQQICHRSKQQGFN	AKAP13	1661	Q12802
SGKLSAAEAQNHCNQ	CD93	41	Q9NPY3
HLLACAQQFRKQTQA	CFAP46	2221	Q8IYW2
FNNTNVRTDCNHIFL	ACACA	1461	Q13085
AKDNFNFLHLNRNAC	ATAD2	771	Q6PL18
KRVHSENNACINFKT	CDK14	91	O94921
EFEGVHSQKQNRQTC	CALN1	216	Q9BXU9
HDDAKQCASLNGVNQ	ADAMTS1	411	Q9UHI8
NSIRHNLSLNDCFVK	FOXD1	171	Q16676
AVQHQALALNSSKCQ	RDM1	101	Q8NG50
NNTSVRTDCNHIFLN	ACACB	1581	O00763
CIKNDLNHSTQFVQG	AP1G1	106	O43747
DRDNSFLQVHNCIQK	CACNG2	291	Q9Y698
NCIQKENKDSLHSNT	CACNG2	301	Q9Y698
KNQHLRLDDCDFQTN	CST7	101	O76096
LKTFAQNCRNIEHLN	FBXL2	96	Q9UKC9
NDARNQAKHAVSNFC	KLHL31	376	Q9H511
RNNSTCLALVDANQH	EYS	861	Q5T1H1
TNERANECSHSKNIQ	DST	2166	Q03001
NECSHSKNIQNFPSD	DST	2171	Q03001
NAKLFCRNHNALLAS	ATRN	811	O75882
QCTRQQKNFNLPASH	KSR2	551	Q6VAB6
FKQNHENLCDNSLQL	DUSP10	276	Q9Y6W6
GDFRAQQCSAHNDVK	ADAMTSL1	86	Q8N6G6
LHNNNFENALCRKES	COX19	41	Q49B96
NCNVAHKNIREQGRF	KCNJ11	41	Q14654
QNSIRHNLSLNKCFV	FOXG1	226	P55316
LKASEHACAALQNNF	EVPL	696	Q92817
SSIVHQINQFCQTRA	FAM222B	266	Q8WU58
SDASNFLQQCSDHKR	DDIAS	141	Q8IXT1
FRHTLQKLTCEFNNN	FBXO39	336	Q8N4B4
QKLTCEFNNNHESLD	FBXO39	341	Q8N4B4
REHALKTQNANQAAS	NRIP1	281	P48552
AAADLKQFCLQNAQH	GNG5	31	P63218
CALHALNNVFQDSNA	JOSD1	36	Q15040
TAGNHCDNLRNRKNE	KRT82	321	Q9NSB4
SDNRIQSVHKNAFNN	LRRC3B	121	Q96PB8
LAQCKELQDHSNQSS	HELZ	1781	P42694
LQAQQDAVNTVCHSK	PIPSL	511	A2A3N6
DLSQCIFNHSQRTLA	GPRC6A	371	Q5T6X5
KDLQAQAFAHICREN	GPRC6A	896	Q5T6X5
SRCQLQQAAALNAQH	ESS2	261	Q96DF8
NLCLNLHKFNEFIQN	APOB	4351	P04114
GANTQDTKNSRHQFC	CD1E	351	P15812
DTKNSRHQFCLAQVS	CD1E	356	P15812
QKHFEDFRAQQCQQR	ADAMTS3	606	O15072
DFRAQQCQQRNSHFE	ADAMTS3	611	O15072
LAFHQELRQSICSNS	C4orf50	251	Q6ZRC1
CKDHFARKQTQRAQS	FAM126A	401	Q9BYI3
AQARCTQHTSKCNLQ	CCDC200	121	A0A1B0GVQ3
TQCFKTQLLNNDGHN	DOCK11	1416	Q5JSL3
NNCANSDRLIKHTSF	DOCK9	1551	Q9BZ29
ANNHCIGTDLNRNFA	CPB2	246	Q96IY4
IHISNELSKNCINNR	EFCAB7	576	A8K855
VSCFQHLVQANVRNK	CACNA2D1	301	P54289
KFQNCIDSFHSRNNS	CHD2	436	O14647
SEAQQERCSQNKSHI	CDC7	216	O00311
RHLKSACEQFIQQQT	COG3	691	Q96JB2
AAQHSQKQSTELFQC	DIS3L	846	Q8TF46
KSREHTSSFNCNFQN	POLQ	961	O75417
HNCNTFSNEVAQFLT	DESI1	106	Q6ICB0
NKHQSAVTCLQFNKN	FBXW7	621	Q969H0
ELQNVRKHIHNCFSN	ATL2	276	Q8NHH9
QNSIRHNLSLNKCFI	FOXJ1	166	Q92949
NCFTFNHGETLQAKR	ASIC5	206	Q9NY37
ISLHNFCLNSKANIA	EFCAB13	951	Q8IY85
SENLNAKNNTNSACF	DCLRE1A	491	Q6PJP8
SNSLQEGACQKRSDH	DCLRE1A	641	Q6PJP8
CRNFHKLNVCRNVNN	CAPN6	331	Q9Y6Q1
TQHNAACKQGQAAAQ	SCNN1D	176	P51172
ANFSAARNDLHKNAN	SACS	4456	Q9NZJ4
FSQVANSGSQCDQRH	DRP2	516	Q13474
QNSIRHNLSLNDCFV	FOXD3	186	Q9UJU5
HRQAQAFNFVKSCKE	PRIMPOL	46	Q96LW4
FKHLSAACQSNKQQV	RALGPS2	561	Q86X27
HQARKSCQQQNAELL	MRC1	241	P22897
DDRFNLAHQIRNKQC	METTL24	166	Q5JXM2
EFGSSKQCHLRQLQQ	PMFBP1	71	Q8TBY8
ANICQVKPNDQHFSR	IGF2R	2191	P11717
NCHNIQTNDTAKTTF	MEIOC	246	A2RUB1
QDNQECLQKHFSRPS	RGS20	6	O76081
KQISLCNDQRHASNH	NEXMIF	651	Q5QGS0
ASTQHQVKNLNRCSV	GNL3L	201	Q9NVN8
VAAQLQCNKRSFSDQ	NR1H2	231	P55055
NCTVIFNNGNHEAVK	SMYD1	211	Q8NB12
HQSCDFLDAASQLQK	PKD1L3	1096	Q7Z443
HCKAQRNLNSFFAIV	RAPGEF5	426	Q92565
CHARHASKVNQQRQQ	SPATA31C1	1076	P0DKV0
CAQHLSQRLQKTFVN	SLC36A3	96	Q495N2
KCAQNEVLRFQTSHS	CCDC136	346	Q96JN2
CNATNRIISHFSQDD	ASCC3	131	Q8N3C0
NSSNDHRFQALQDNC	ASCC3	296	Q8N3C0
CNSAHILQNKTNDNC	C12orf40	571	Q86WS4
ANLLNEQNCVTHSKA	CNNM2	851	Q9H8M5
NECGKVFTQNSHLAN	ZNF665	601	Q9H7R5
HTNACVQQNSSFVDR	ZNF572	116	Q7Z3I7
NQNAAFSKCHSKVNP	TECTA	1306	O75443
NHNIQQESRTFCKEE	XIRP2	3186	A4UGR9
GKALSQCQSFNIHQK	ZNF667	231	Q5HYK9
LHQSLHQSQKQFQCE	ZBTB11	696	O95625
SKNNELQNSARCSNL	ZNF394	281	Q53GI3
QANISQSHKDRVCTF	VSTM5	86	A8MXK1
CSKVFTQNSQLANHR	ZNF160	486	Q9HCG1
NECGKVFTQNAHLAN	ZNF160	736	Q9HCG1
LAHQCFRLALVNNNN	TTC8	441	Q8TAM2
CGKAFTQSSQLRQHQ	ZNF383	371	Q8NA42
KSVFCNKNQINFNHD	ZNF519	151	Q8TB69
RQQQHLFGSNVTDCS	TF	621	P02787
NSHGSSECIKIQNQR	ARHGAP28	676	Q9P2N2
QNNATFDCKVLSRNH	SLMAP	41	Q14BN4
SVCYKEHLQRQNSSN	ZFAND6	31	Q6FIF0
NSQKIRHTGNNSFKC	ZNF723	161	P0DPD5
CGKAFTSNRNLVDHQ	ZNF660	251	Q6AZW8
RYNQRNSKSNQCLHL	ZHX1	516	Q9UKY1
NECGKAFNQQSHLSR	ZNF808	346	Q8N4W9
QCNKAFSQLAHLAQH	ZNF470	316	Q6ECI4
NKHRNCDKFEVNTQS	NF1	2421	P21359
LQNKIVHFSANACLA	XDH	61	P47989
TNVHTDACANNIAQR	RFX7	1111	Q2KHR2
FSLKNLDNSVHLCNN	TTLL3	366	Q9Y4R7
VCQLRFNSDSQAEAH	ZNF385B	161	Q569K4
CGKSFNRVSNLVQHQ	ZNF780B	646	Q9Y6R6
AESNVTLKCQAHSQN	VSTM1	41	Q6UX27
CGKAFSQKSQLINHQ	ZNF84	716	P51523
ECGKVFSRNSQLSQH	ZNF347	321	Q96SE7
NECGKVFTQNSHLAN	ZNF347	516	Q96SE7
NECGKVFTQNSHLAR	ZNF347	656	Q96SE7
RHINFCKEQAARISN	ZC2HC1A	136	Q96GY0
DANIHTQSKAQQCVS	ZNF507	181	Q8TCN5
QQDFHPKCSTANSRL	USP24	1621	Q9UPU5
CGKAFSQRSNLVQHQ	ZNF570	251	Q96NI8
SCELRNLKSVQNSHF	TTK	321	P33981
NQCGKAFNRSSNLIH	ZNF16	576	P17020
CGKAFNQTANLIQHQ	ZNF454	501	Q8N9F8
HECGKDFNQSSNLVR	ZNF594	186	Q96JF6
NFLQANFQTHLREAC	ZNF687	741	Q8N1G0
NECDKAFNQQSQLSH	ZNF611	346	Q8N823
NECGKAFNQQSHLSR	ZNF611	681	Q8N823
TSRSAFQCLQKFQQH	SNAPC4	326	Q5SXM2
NECGKAFSQSAHLNQ	ZNF713	401	Q8N859
CGEAFSQKSNLRVHQ	ZNF782	651	Q6ZMW2
NDCHKVFSNATTIAN	ZNF860	401	A6NHJ4
ICEKSFIQRSNFNRH	ZNF18	496	P17022
CGKSFTRNSNLVQHQ	ZNF883	46	P0CG24
QCFSLKSNLNKHQRS	ZNF875	476	P10072
EECGKRFTQNSQLHS	ZNF224	571	Q9NZL3
VFSRCNSNFVVRHNN	MID2	626	Q9UJV3
TNNEVHNLTECKNAS	PTPRC	266	P08575
NTLVRNESHKNCDFR	PTPRC	526	P08575
CGKSFRQNSALTQHQ	ZSCAN12	586	O43309
CGKAFISNSNLIQHQ	ZNF571	396	Q7Z3V5
GHICSEQNTNDREKN	PJA2	291	O43164
ICNRHQAFVKASNQI	TMEM251	141	Q8N6I4
NNLDAFVAHKQSGCQ	ZFP64	41	Q9NTW7
CQRHTDAQAQASAAL	PPIP5K1	1116	Q6PFW1
TTNNTFANEDSHRKC	ZC3H13	1146	Q5T200
CGKAFNNRSNFNKHQ	ZNF175	676	Q9Y473
CGKSFAQTSNLRQHQ	ZNF628	571	Q5EBL2
CNKAFRQSAHLNQHQ	ZNF527	391	Q8NB42
LCDRTFNNSSNFRKH	ZNF784	256	Q8NCA9
NTSRQNEHCLTNFDL	MYO5A	1581	Q9Y4I1
TQNTAKQNEHCLKNF	MYO5B	1571	Q9ULV0
AAECKQSQRNAANAR	MSC	101	O60682
QSCNFALRFFHSNQK	NAA25	561	Q14CX7