Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	DDX19B DDX19A DNAH3 MYH6 ABCA4 MYO7A MYH7B ABCB6 BTAF1 KIF24 ABCA5 CHTF18 DDX54 MACF1 DDX11L8	4.53e-07	614	101	15	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal protein binding	MYH6 MAP7D3 MYO7A MYH7B APC ARFGEF2 CLSTN1 KIF24 POF1B LRPPRC HAUS4 ARHGEF7 PKD2 MACF1 TLN2 DLG4 MAPRE2 MTUS2 NIN	2.23e-06	1099	101	19	GO:0008092
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX19B DDX19A DNAH3 ABCA4 ABCB6 BTAF1 ABCA5 CHTF18 DDX54 MACF1 DDX11L8	1.44e-05	441	101	11	GO:0016887
GeneOntologyMolecularFunction	microtubule binding	MAP7D3 APC KIF24 LRPPRC HAUS4 MACF1 MAPRE2 MTUS2 NIN	2.65e-05	308	101	9	GO:0008017
GeneOntologyMolecularFunction	microtubule minus-end binding	HAUS4 MACF1 NIN	5.47e-05	15	101	3	GO:0051011
GeneOntologyMolecularFunction	tubulin binding	MAP7D3 APC KIF24 LRPPRC HAUS4 ARHGEF7 MACF1 MAPRE2 MTUS2 NIN	6.23e-05	428	101	10	GO:0015631
GeneOntologyMolecularFunction	helicase activity	DDX19B DDX19A BTAF1 CHTF18 DDX54 DDX11L8	1.52e-04	158	101	6	GO:0004386
GeneOntologyMolecularFunction	actin filament binding	MYH6 MYO7A MYH7B POF1B LRPPRC MACF1 TLN2	1.56e-04	227	101	7	GO:0051015
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH3 MYH6 MYO7A MYH7B KIF24	3.34e-04	118	101	5	GO:0003774
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DDX19B DDX19A DNAH3 ABCA4 ABCB6 BTAF1 SEPTIN8 ABCA5 CHTF18 DDX54 MACF1 DDX11L8	5.40e-04	775	101	12	GO:0017111
GeneOntologyMolecularFunction	RNA helicase activity	DDX19B DDX19A DDX54 DDX11L8	6.60e-04	78	101	4	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DDX19B DDX19A DDX54 DDX11L8	7.26e-04	80	101	4	GO:0008186
GeneOntologyMolecularFunction	microfilament motor activity	MYH6 MYO7A MYH7B	9.32e-04	38	101	3	GO:0000146
GeneOntologyMolecularFunction	pyrophosphatase activity	DDX19B DDX19A DNAH3 ABCA4 ABCB6 BTAF1 SEPTIN8 ABCA5 CHTF18 DDX54 MACF1 DDX11L8	1.08e-03	839	101	12	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DDX19B DDX19A DNAH3 ABCA4 ABCB6 BTAF1 SEPTIN8 ABCA5 CHTF18 DDX54 MACF1 DDX11L8	1.09e-03	840	101	12	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DDX19B DDX19A DNAH3 ABCA4 ABCB6 BTAF1 SEPTIN8 ABCA5 CHTF18 DDX54 MACF1 DDX11L8	1.09e-03	840	101	12	GO:0016818
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA4 ABCB6 ABCA5	1.95e-03	49	101	3	GO:0140359
GeneOntologyBiologicalProcess	microtubule polymerization or depolymerization	MAP7D3 APC KIF24 HAUS4 ARHGEF7 MAPRE2 NIN	1.46e-05	168	97	7	GO:0031109
GeneOntologyBiologicalProcess	ventricular cardiac muscle tissue development	MYH6 COL11A1 DSG2 TGFBR3 NOTCH1	2.94e-05	76	97	5	GO:0003229
GeneOntologyBiologicalProcess	striated muscle tissue development	HDAC9 MYH6 COL11A1 DSG2 APC TSC1 TGFBR3 NPRL3 NOTCH1	3.96e-05	349	97	9	GO:0014706
GeneOntologyCellularComponent	cell cortex	MYO7A APC TSC1 SEPTIN8 FRY ARHGEF7 PKD2 MACF1 DLG4 PDZD4	1.26e-05	371	101	10	GO:0005938
GeneOntologyCellularComponent	anchoring junction	DSG2 APC ITGA2B ITGA7 POF1B ARHGAP31 BSG ARHGEF7 CD99 PKD2 TLN2 DLG4 MAPRE2 NOTCH1	2.48e-04	976	101	14	GO:0070161
GeneOntologyCellularComponent	microtubule	DNAH3 APC ARFGEF2 KIF24 LRPPRC HAUS4 MACF1 MAPRE2 MTUS2 NIN	2.57e-04	533	101	10	GO:0005874
GeneOntologyCellularComponent	postsynapse	APC ARFGEF2 GABRQ TSC1 SRGAP2 CLSTN1 GPR179 RNF220 ARHGEF7 MACF1 DLG4 CADPS2 USP48 NOTCH1	3.80e-04	1018	101	14	GO:0098794
GeneOntologyCellularComponent	spindle	MAP7D3 FRY HAUS4 TMEM9 ARHGEF7 PKD2 MAPRE2 DDX11L8 NIN	4.63e-04	471	101	9	GO:0005819
GeneOntologyCellularComponent	cytoplasmic microtubule	APC ARFGEF2 MAPRE2 MTUS2 NIN	4.70e-04	133	101	5	GO:0005881
GeneOntologyCellularComponent	microtubule organizing center	APC ARFGEF2 KIF24 FRY HAUS4 ARHGEF7 PKD2 CTNNBL1 PRKCQ MAPRE2 DDX11L8 MTUS2 NIN	4.79e-04	919	101	13	GO:0005815
GeneOntologyCellularComponent	supramolecular fiber	DNAH3 MYH6 COL11A1 MYH7B APC ARFGEF2 TSC1 KIF24 POF1B LRPPRC HAUS4 MACF1 MAPRE2 MTUS2 NIN	5.26e-04	1179	101	15	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	DNAH3 MYH6 COL11A1 MYH7B APC ARFGEF2 TSC1 KIF24 POF1B LRPPRC HAUS4 MACF1 MAPRE2 MTUS2 NIN	5.64e-04	1187	101	15	GO:0099081
GeneOntologyCellularComponent	postsynaptic membrane	GABRQ SRGAP2 CLSTN1 GPR179 DLG4 CADPS2 USP48 NOTCH1	7.80e-04	405	101	8	GO:0045211
GeneOntologyCellularComponent	lamellipodium	APC TSC1 SRGAP2 ARHGAP31 ARHGEF7 PKD2	8.83e-04	230	101	6	GO:0030027
GeneOntologyCellularComponent	Ctf18 RFC-like complex	CHTF18 DDX11L8	1.01e-03	10	101	2	GO:0031390
GeneOntologyCellularComponent	centrosome	APC ARFGEF2 KIF24 FRY HAUS4 ARHGEF7 CTNNBL1 PRKCQ DDX11L8 MTUS2 NIN	1.23e-03	770	101	11	GO:0005813
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	DNAH3 APC ARFGEF2 TSC1 KIF24 POF1B LRPPRC HAUS4 MACF1 MAPRE2 MTUS2 NIN	1.32e-03	899	101	12	GO:0099513
GeneOntologyCellularComponent	cell-substrate junction	ITGA2B ITGA7 ARHGAP31 BSG ARHGEF7 CD99 TLN2 MAPRE2	1.38e-03	443	101	8	GO:0030055
GeneOntologyCellularComponent	late endosome membrane	SLC11A2 ABCB6 WDR91 TMEM9 ABCA5	1.78e-03	179	101	5	GO:0031902
GeneOntologyCellularComponent	photoreceptor outer segment	ABCA4 MYO7A WDR19 BSG	2.07e-03	111	101	4	GO:0001750
GeneOntologyCellularComponent	non-motile cilium	ABCA4 MYO7A WDR19 BSG PKD2	2.64e-03	196	101	5	GO:0097730
GeneOntologyCellularComponent	Seh1-associated complex	SESN1 NPRL3	2.65e-03	16	101	2	GO:0035859
GeneOntologyCellularComponent	myosin complex	MYH6 MYO7A MYH7B	2.93e-03	59	101	3	GO:0016459
GeneOntologyCellularComponent	cell leading edge	APC TSC1 SRGAP2 ARHGAP31 ARHGEF7 PKD2 MACF1 TLN2	2.93e-03	500	101	8	GO:0031252
GeneOntologyCellularComponent	mitotic spindle	HAUS4 TMEM9 ARHGEF7 PKD2 NIN	2.94e-03	201	101	5	GO:0072686
Domain	P-loop_NTPase	DDX19B DDX19A DNAH3 MYH6 ABCA4 MYO7A MYH7B ABCB6 BTAF1 KIF24 SEPTIN8 ABCA5 CHTF18 DDX54 DLG4 HYDIN	1.07e-05	848	100	16	IPR027417
Domain	-	DDX19B DDX19A DNAH3 ABCA4 MYO7A ABCB6 BTAF1 SEPTIN8 ABCA5 CHTF18 DDX54 DLG4 HYDIN	1.71e-04	746	100	13	3.40.50.300
Domain	Q_MOTIF	DDX19B DDX19A DDX54	1.01e-03	37	100	3	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX19B DDX19A DDX54	1.01e-03	37	100	3	IPR014014
Domain	AAA+_ATPase	DNAH3 ABCA4 ABCB6 ABCA5 CHTF18	1.06e-03	144	100	5	IPR003593
Domain	AAA	DNAH3 ABCA4 ABCB6 ABCA5 CHTF18	1.06e-03	144	100	5	SM00382
Domain	Myosin_head_motor_dom	MYH6 MYO7A MYH7B	1.10e-03	38	100	3	IPR001609
Domain	MYOSIN_MOTOR	MYH6 MYO7A MYH7B	1.10e-03	38	100	3	PS51456
Domain	Myosin_head	MYH6 MYO7A MYH7B	1.10e-03	38	100	3	PF00063
Domain	MYSc	MYH6 MYO7A MYH7B	1.10e-03	38	100	3	SM00242
Domain	ABC_transporter_CS	ABCA4 ABCB6 ABCA5	1.47e-03	42	100	3	IPR017871
Domain	Integrin_alpha	ITGA2B ITGA7	1.51e-03	11	100	2	PF00357
Domain	ABC_A	ABCA4 ABCA5	1.81e-03	12	100	2	IPR026082
Domain	ABC_tran	ABCA4 ABCB6 ABCA5	2.16e-03	48	100	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA4 ABCB6 ABCA5	2.16e-03	48	100	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCA4 ABCB6 ABCA5	2.30e-03	49	100	3	PS00211
Domain	ABC_transporter-like	ABCA4 ABCB6 ABCA5	2.43e-03	50	100	3	IPR003439
Domain	Helicase_C	DDX19B DDX19A BTAF1 DDX54	2.62e-03	107	100	4	PF00271
Domain	HELICc	DDX19B DDX19A BTAF1 DDX54	2.62e-03	107	100	4	SM00490
Domain	Helicase_C	DDX19B DDX19A BTAF1 DDX54	2.71e-03	108	100	4	IPR001650
Domain	HELICASE_CTER	DDX19B DDX19A BTAF1 DDX54	2.80e-03	109	100	4	PS51194
Domain	HELICASE_ATP_BIND_1	DDX19B DDX19A BTAF1 DDX54	2.80e-03	109	100	4	PS51192
Domain	DEXDc	DDX19B DDX19A BTAF1 DDX54	2.80e-03	109	100	4	SM00487
Domain	Myosin_N	MYH6 MYH7B	2.85e-03	15	100	2	PF02736
Domain	Myosin_N	MYH6 MYH7B	2.85e-03	15	100	2	IPR004009
Domain	Helicase_ATP-bd	DDX19B DDX19A BTAF1 DDX54	2.89e-03	110	100	4	IPR014001
Domain	Integrin_alpha_C_CS	ITGA2B ITGA7	3.24e-03	16	100	2	IPR018184
Domain	Integrin_alpha-2	ITGA2B ITGA7	4.11e-03	18	100	2	IPR013649
Domain	Integrin_alpha2	ITGA2B ITGA7	4.11e-03	18	100	2	PF08441
Domain	Myosin_tail_1	MYH6 MYH7B	4.11e-03	18	100	2	PF01576
Domain	Integrin_alpha	ITGA2B ITGA7	4.11e-03	18	100	2	IPR000413
Domain	Myosin_tail	MYH6 MYH7B	4.11e-03	18	100	2	IPR002928
Domain	INTEGRIN_ALPHA	ITGA2B ITGA7	4.11e-03	18	100	2	PS00242
Domain	RhoGAP	SRGAP2 FAM13A ARHGAP31	4.48e-03	62	100	3	SM00324
Domain	Int_alpha_beta-p	ITGA2B ITGA7	4.57e-03	19	100	2	IPR013519
Domain	Int_alpha	ITGA2B ITGA7	4.57e-03	19	100	2	SM00191
Domain	Myosin-like_IQ_dom	MYH6 MYH7B	4.57e-03	19	100	2	IPR027401
Domain	-	MYH6 MYH7B	4.57e-03	19	100	2	4.10.270.10
Domain	RhoGAP	SRGAP2 FAM13A ARHGAP31	4.69e-03	63	100	3	PF00620
Domain	RHOGAP	SRGAP2 FAM13A ARHGAP31	4.90e-03	64	100	3	PS50238
Domain	RhoGAP_dom	SRGAP2 FAM13A ARHGAP31	4.90e-03	64	100	3	IPR000198
Domain	-	SRGAP2 FAM13A ARHGAP31	4.90e-03	64	100	3	1.10.555.10
Domain	USP_CS	USP34 USP29 USP48	5.34e-03	66	100	3	IPR018200
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MAP7D3 DSG2 RCN2 APC LRRC40 GFPT1 LRPPRC FARSA NUP155 BSG MACF1 MAPRE2 IMMT NOTCH1 GOLGA4	2.88e-09	708	103	15	39231216
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	HDAC9 USP34 APC ARFGEF2 SRGAP2 GFPT1 WDR19 RNF220 FRY FBXO7 KCNN1 MACF1 TLN2 DLG4 CADPS2 IMMT TRIM37 MTUS2	4.11e-08	1285	103	18	35914814
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	APC ZFX NCOR2 FRY FAM193A NUP155 ARHGEF7 KANK4 TLN2 IMMT MTUS2	1.77e-07	475	103	11	31040226
Pubmed	Defining the membrane proteome of NK cells.	DDX19B DDX19A SLC11A2 MAP7D3 CNOT10 ARFGEF2 LRRC40 NCOR2 LRPPRC FARSA NUP155 BSG CHTF18 DDX54 CTNNBL1 IMMT	3.42e-07	1168	103	16	19946888
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	UACA DSG2 PMPCB RCN2 LRRC40 WDR19 LRPPRC FAM193A NUP155 BSG CD99 DDX54 MACF1 SIPA1L2 USP48 IMMT GOLGA4 NIN	3.57e-07	1487	103	18	33957083
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CPA4 DDX19A PMPCB LRRC40 TSC1 GFPT1 NCOR2 LRPPRC PSME4 NUP155 CHTF18 DDX54 CTNNBL1 MACF1 MAPRE2 IMMT GOLGA4	4.71e-07	1353	103	17	29467282
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CNOT10 RCN2 APC SRGAP2 FAM193A SIPA1L2 CDC25C TRIM37 NOTCH1 NIN	8.87e-07	446	103	10	24255178
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	UACA APC TSC1 SRGAP2 WDR91 NCOR2 LRPPRC FRY FARSA ARHGEF7 MACF1 TLN2 DLG4 GOLGA4	9.93e-07	963	103	14	28671696
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	USP34 DDX19A DSG2 PMPCB RCN2 POF1B GFPT1 LRPPRC NUP155 DDX54 DLG4 SIPA1L2 CDC25C IMMT	1.13e-06	974	103	14	28675297
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	UACA APC MACF1 IMMT TRIM37 GOLGA4	1.62e-06	120	103	6	31413325
Pubmed	EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.	APC MACF1 MTUS2	2.98e-06	10	103	3	23001180
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	MAP7D3 RCN2 APC SRGAP2 NCOR2 LRPPRC FRY HAUS4 DDX54 SIPA1L2 TRIM37	3.20e-06	639	103	11	23443559
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 JADE3 WDR19 SEPTIN8 PSME4 NUP155 ABCA5 ARHGAP31 ARHGEF7 NIN	4.06e-06	529	103	10	14621295
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	UACA DSG2 SRGAP2 ITGA7 LRPPRC NUP155 BSG MACF1 SIPA1L2	4.72e-06	421	103	9	36976175
Pubmed	The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.	TSC1 SESN1 NPRL3	5.44e-06	12	103	3	25263562
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TSC1 SLC22A17 FAM13A BSG ARHGEF7 FBXO7 KCNN1 DLG4 MTUS2 NOTCH1	6.68e-06	560	103	10	21653829
Pubmed	Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.	APC NOTCH1	8.69e-06	2	103	2	22863622
Pubmed	Interaction between p230 and MACF1 is associated with transport of a glycosyl phosphatidyl inositol-anchored protein from the Golgi to the cell periphery.	MACF1 GOLGA4	8.69e-06	2	103	2	15265687
Pubmed	Oral interleukin-10 alleviates polyposis via neutralization of pathogenic T-regulatory cells.	RAG1 APC	8.69e-06	2	103	2	25228656
Pubmed	Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction.	CD99 GOLGA4	8.69e-06	2	103	2	18849489
Pubmed	TMEM9-v-ATPase Activates Wnt/β-Catenin Signaling Via APC Lysosomal Degradation for Liver Regeneration and Tumorigenesis.	APC TMEM9	8.69e-06	2	103	2	32380568
Pubmed	Protein kinase C-theta is required for efficient positive selection.	RAG1 PRKCQ	8.69e-06	2	103	2	18802072
Pubmed	Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.	APC MAPRE2	8.69e-06	2	103	2	16763565
Pubmed	Digenic mutational inheritance of the integrin alpha 7 and the myosin heavy chain 7B genes causes congenital myopathy with left ventricular non-compact cardiomyopathy.	MYH7B ITGA7	8.69e-06	2	103	2	23800289
Pubmed	Increased leukemia-associated gene expression in benzene-exposed workers.	BSG NOTCH1	8.69e-06	2	103	2	24993241
Pubmed	Gamma-secretase complex-dependent intramembrane proteolysis of CD147 regulates the Notch1 signaling pathway in hepatocellular carcinoma.	BSG NOTCH1	8.69e-06	2	103	2	31215640
Pubmed	DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.	DDX19B DDX19A	8.69e-06	2	103	2	30699353
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	MAP7D3 DSG2 JADE3 RCN2 APC TSC1 GFPT1 SEPTIN8 HAUS4 SIPA1L2 TRIM37 NIN	8.70e-06	853	103	12	28718761
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	DDX19B CNOT10 USP29 APC RNF220 LRPPRC FARSA NUP155 BSG FBXO7 USP48 IMMT NIN	8.79e-06	1005	103	13	19615732
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DDX19B DDX19A ARFGEF2 LRRC40 BTAF1 NCOR2 NUP155 MACF1 TLN2 USP48	9.33e-06	582	103	10	20467437
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	USP34 APC TSC1 NCOR2 FARSA HAUS4 MACF1 SIPA1L2 TRIM37 NIN	1.02e-05	588	103	10	38580884
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	HDAC9 USP34 NUP155 MACF1 MTUS2	1.31e-05	101	103	5	9872452
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MAP7D3 APC FAM193A NUP155 MACF1 SIPA1L2 PDZD4	1.39e-05	263	103	7	34702444
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HDHD5 LRRC40 TSC1 SRGAP2 GFPT1 LRPPRC FARSA NUP155 ARHGEF7 CHTF18 DDX54 CTNNBL1 MACF1 IMMT GOLGA4	1.82e-05	1415	103	15	28515276
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	MAP7D3 NCOR2 FAM193A ARHGAP31 TRIM37 NOTCH1	1.89e-05	184	103	6	32908313
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DDX19A DSG2 PMPCB RCN2 LRRC40 GFPT1 LRPPRC FARSA NUP155 BSG DDX54 CTNNBL1 TLN2 IMMT GOLGA4	1.98e-05	1425	103	15	30948266
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	DDX19B DDX19A HDHD5 RCN2 BTAF1 GFPT1 LRPPRC FARSA PSME4 NUP155 BSG CHTF18 FBXO7 IMMT	2.07e-05	1257	103	14	37317656
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MYH6 MYO7A APC ARFGEF2 TSC1 SRGAP2 SEPTIN8 LRPPRC FARSA MACF1 TLN2 DLG4 SIPA1L2 IMMT MTUS2	2.08e-05	1431	103	15	37142655
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	DSG2 LRRC40 BTAF1 CLSTN1 GFPT1 LRPPRC FARSA NUP155 TMEM9 BSG MAPRE2 IMMT	2.32e-05	942	103	12	31073040
Pubmed	Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis.	RAG1 SLC11A2	2.60e-05	3	103	2	20959604
Pubmed	Lineage tracing of Notch1-expressing cells in intestinal tumours reveals a distinct population of cancer stem cells.	APC NOTCH1	2.60e-05	3	103	2	30696875
Pubmed	T-cell Expression of IL10 Is Essential for Tumor Immune Surveillance in the Small Intestine.	RAG1 APC	2.60e-05	3	103	2	25855122
Pubmed	Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth.	APC GFPT1	2.60e-05	3	103	2	38732103
Pubmed	Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain.	CLSTN1 DLG4	2.60e-05	3	103	2	11161476
Pubmed	The colorectal tumour suppressor APC is present in the NMDA-receptor-PSD-95 complex in the brain.	APC DLG4	2.60e-05	3	103	2	11029657
Pubmed	APC binds to the novel protein EB1.	APC MAPRE2	2.60e-05	3	103	2	7606712
Pubmed	Protein kinase C theta plays a fundamental role in different types of chronic colitis.	RAG1 PRKCQ	2.60e-05	3	103	2	18155708
Pubmed	A functional role for Smad7 in sustaining colon cancer cell growth and survival.	RAG1 APC	2.60e-05	3	103	2	24556688
Pubmed	Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.	TLN2 PRKCQ	2.60e-05	3	103	2	18792400
Pubmed	Genetic Etiology of Left-Sided Obstructive Heart Lesions: A Story in Development.	MYH6 NOTCH1	2.60e-05	3	103	2	33432820
Pubmed	Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.	APC NOTCH1	2.60e-05	3	103	2	17215306
Pubmed	Genotype-ocular biometry correlation analysis of eight primary angle closure glaucoma susceptibility loci in a cohort from Northern China.	COL11A1 GLIS3	2.60e-05	3	103	2	30399154
Pubmed	Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis.	SLC11A2 APC	2.60e-05	3	103	2	27546461
Pubmed	X chromosome genes and premature ovarian failure.	POF1B ZFX	2.60e-05	3	103	2	11299520
Pubmed	RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1.	DDX19B DDX19A	2.60e-05	3	103	2	25585691
Pubmed	Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming.	RAG1 APC	2.60e-05	3	103	2	21303980
Pubmed	Novel Genetic Variants of Sporadic Atrial Septal Defect (ASD) in a Chinese Population Identified by Whole-Exome Sequencing (WES).	MYH6 HYDIN	2.60e-05	3	103	2	29505555
Pubmed	Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells.	RAG1 NOTCH1	2.60e-05	3	103	2	23115273
Pubmed	Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization.	APC MAPRE2	2.60e-05	3	103	2	11470413
Pubmed	Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis.	RAG1 TSC1	2.60e-05	3	103	2	37967531
Pubmed	Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation.	MYO7A NOTCH1	2.60e-05	3	103	2	34519870
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	DDX19A HDHD5 LRRC40 GFPT1 LRPPRC FARSA NUP155 BSG MAPRE2	3.10e-05	534	103	9	35032548
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	DDX19B DDX19A POF1B GFPT1 LRPPRC PSME4 NUP155	3.52e-05	304	103	7	32235678
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCA4 ABCB6 ABCA5	3.73e-05	22	103	3	8894702
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	UACA DSG2 CNOT10 RCN2 APC KIF24 POF1B HAUS4 NUP155 BSG CTNNBL1 TLN2 CDC25C	3.76e-05	1155	103	13	20360068
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DDX19B MAP7D3 DSG2 APC SRGAP2 LRPPRC FAM13A MACF1 SIPA1L2 CDC25C GOLGA4	5.06e-05	861	103	11	36931259
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	SLC11A2 UACA DSG2 ARFGEF2 TSC1 ARHGAP31 BSG CD99 NOTCH1	5.06e-05	569	103	9	30639242
Pubmed	First Report of FARSA in the Regulation of Cell Cycle and Survival in Mantle Cell Lymphoma Cells via PI3K-AKT and FOXO1-RAG1 Axes.	RAG1 FARSA	5.19e-05	4	103	2	36675119
Pubmed	The Notch signaling pathway controls CD8+ T cell differentiation independently of the classical effector HES1.	RAG1 NOTCH1	5.19e-05	4	103	2	30951556
Pubmed	Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein.	NCOR2 NOTCH1	5.19e-05	4	103	2	22888005
Pubmed	Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine.	APC NOTCH1	5.19e-05	4	103	2	19251639
Pubmed	SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function.	NCOR2 NOTCH1	5.19e-05	4	103	2	10713164
Pubmed	Notch transactivates Rheb to maintain the multipotency of TSC-null cells.	TSC1 NOTCH1	5.19e-05	4	103	2	29184052
Pubmed	Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in GPIIb-IIIa activation.	ITGA2B PRKCQ	5.19e-05	4	103	2	14525764
Pubmed	A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis.	MYO7A DLG4	5.19e-05	4	103	2	15657400
Pubmed	SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner.	RAG1 PRKCQ	5.19e-05	4	103	2	29282318
Pubmed	NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.	PRKCQ NOTCH1	5.19e-05	4	103	2	23086478
Pubmed	CD4 raft association and signaling regulate molecular clustering at the immunological synapse site.	TLN2 PRKCQ	5.19e-05	4	103	2	15128768
Pubmed	Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein.	APC DLG4	5.19e-05	4	103	2	9326658
Pubmed	TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/β-catenin signalling.	APC TMEM9	5.19e-05	4	103	2	30374053
Pubmed	Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.	APC NOTCH1	5.19e-05	4	103	2	23776410
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	UACA DSG2 PMPCB APC BTAF1 ARHGEF7 CD99 CENPI MACF1 GOLGA4	5.62e-05	719	103	10	35337019
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMPCB RCN2 TSC1 NCOR2 NUP155 BSG DDX54 CDC25C MAPRE2 NOTCH1 GOLGA4 NIN	6.55e-05	1049	103	12	27880917
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	UACA HDHD5 RCN2 TSC1 POF1B GFPT1 LRPPRC ARHGEF7 MACF1	7.69e-05	601	103	9	33658012
Pubmed	SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166.	DSG2 POF1B TLN2	7.83e-05	28	103	3	32801337
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	ABCA4 MYO7A MYH7B ABCB6 KIF24 LRPPRC FARSA BBX TMEM9 KMT5B ARHGEF7 FBXO7 DLG4	7.85e-05	1242	103	13	30973865
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	DDX19B UACA RCN2 APC GFPT1 NCOR2 LRPPRC FARSA BSG CHTF18 DDX54 NPRL3 IMMT	8.18e-05	1247	103	13	27684187
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DDX19B DDX19A DSG2 PMPCB HDHD5 LRPPRC NUP155 DDX54 SIPA1L2	8.19e-05	606	103	9	36538041
Pubmed	Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome.	APC MAPRE2	8.64e-05	5	103	2	12388762
Pubmed	p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling.	TSC1 SESN1	8.64e-05	5	103	2	18692468
Pubmed	Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.	APC MACF1	8.64e-05	5	103	2	17113391
Pubmed	Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.	RAG1 NOTCH1	8.64e-05	5	103	2	23377202
Pubmed	Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.	RAG1 APC	8.64e-05	5	103	2	26880802
Pubmed	EB/RP gene family encodes tubulin binding proteins.	APC MAPRE2	8.64e-05	5	103	2	10188731
Pubmed	Long-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nail.	SERPINB2 NOTCH1	8.64e-05	5	103	2	14597207
Pubmed	Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages.	RAG1 ITGA2B	8.64e-05	5	103	2	18371378
Pubmed	Characterization of functional domains of human EB1 family proteins.	APC MAPRE2	8.64e-05	5	103	2	14514668
Pubmed	Introduction of cytogenetic tests in colorectal cancer screening.	COL11A1 APC	8.64e-05	5	103	2	19337631
Pubmed	Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival.	HDAC9 RAG1	8.64e-05	5	103	2	25681462
Pubmed	Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.	NCOR2 NOTCH1	8.64e-05	5	103	2	21475249
Interaction	EGLN3 interactions	USP34 MAP7D3 ACD DSG2 CNOT10 HDHD5 RCN2 APC LRRC40 BTAF1 GFPT1 NCOR2 LRPPRC FARSA HAUS4 FAM193A BSG CHTF18 SIPA1L2 MAPRE2 IMMT TRIM37 NIN	1.19e-07	1296	103	23	int:EGLN3
Interaction	CTNNB1 interactions	ABCA4 UACA DSG2 MYO7A USP29 APC ARFGEF2 TSC1 GFPT1 RNF220 LRPPRC FARSA FAM193A ABCA5 DLG4 SIPA1L2 USP48 IMMT TRIM37 NOTCH1	1.60e-07	1009	103	20	int:CTNNB1
Interaction	CAMSAP2 interactions	MAP7D3 SRGAP2 KIF24 MACF1 CDC25C MAPRE2 IMMT TRIM37 NIN	2.12e-07	169	103	9	int:CAMSAP2
Interaction	KCNA3 interactions	MAP7D3 DSG2 MYH7B RCN2 APC LRRC40 GFPT1 LRPPRC FARSA NUP155 BSG MACF1 TLN2 DLG4 MAPRE2 IMMT NOTCH1 GOLGA4	4.00e-07	871	103	18	int:KCNA3
Interaction	CLEC2B interactions	RCN2 ARFGEF2 GABRQ BTAF1 B3GNT3 TGFBR3 TMEM9 NOTCH1	8.77e-07	147	103	8	int:CLEC2B
Interaction	SYNE3 interactions	CNOT10 RCN2 APC TSC1 NCOR2 FARSA FAM193A NUP155 MACF1 SIPA1L2 TRIM37 NIN	2.82e-06	444	103	12	int:SYNE3
Interaction	RAC2 interactions	SLC11A2 DSG2 ARFGEF2 NUP155 TMEM9 BSG ARHGEF7 CD99 DDX54 MACF1 TLN2 IMMT NOTCH1 GOLGA4	8.44e-06	674	103	14	int:RAC2
Interaction	LGI1 interactions	TSC1 CHTF18 FBXO7 DLG4 MAPRE2	1.38e-05	60	103	5	int:LGI1
Interaction	RAC3 interactions	SLC11A2 UACA DSG2 SRGAP2 NUP155 TMEM9 BSG ARHGEF7 CD99 MACF1 IMMT NOTCH1 GOLGA4	1.62e-05	619	103	13	int:RAC3
Interaction	HDAC4 interactions	DDX19B HDAC9 APC SRGAP2 ZFX NCOR2 FRY FAM193A NUP155 BSG KANK4 TLN2 CDC25C MTUS2	2.54e-05	744	103	14	int:HDAC4
Interaction	RAC1 interactions	SLC11A2 DSG2 TSC1 SRGAP2 LRPPRC NUP155 FAM13A TMEM9 ARHGAP31 BSG ARHGEF7 CD99 MACF1 DLG4 USP48 IMMT NOTCH1	2.61e-05	1063	103	17	int:RAC1
Interaction	PPARD interactions	USP34 APC NCOR2 CHTF18 FBXO7 NPRL3	3.04e-05	117	103	6	int:PPARD
Interaction	YWHAZ interactions	HDAC9 MAP7D3 UACA DSG2 APC TSC1 SRGAP2 ITGA2B LRPPRC FAM13A KMT5B ARHGEF7 MACF1 DLG4 SIPA1L2 CDC25C USP48 TRIM37 NIN	3.51e-05	1319	103	19	int:YWHAZ
Interaction	RHOF interactions	DDX19B SLC11A2 UACA DSG2 ARFGEF2 SRGAP2 NUP155 BSG CD99 DDX54 MACF1 IMMT NOTCH1	3.87e-05	673	103	13	int:RHOF
Interaction	CHCHD2 interactions	DSG2 PMPCB TSC1 RNF220 HAUS4 ARHGAP31 DDX54 FBXO7	4.08e-05	248	103	8	int:CHCHD2
Interaction	SPSB4 interactions	DSG2 LRRC40 BTAF1 RNF220 MAPRE2 IMMT	4.22e-05	124	103	6	int:SPSB4
Interaction	RAB9A interactions	DDX19A SLC11A2 DSG2 ARFGEF2 TSC1 WDR91 NUP155 TMEM9 BSG DDX54 IMMT GOLGA4	5.20e-05	595	103	12	int:RAB9A
Interaction	PXN interactions	MAP7D3 CNOT10 APC HAUS4 ARHGEF7 MACF1 SIPA1L2 GOLGA4 NIN	5.42e-05	334	103	9	int:PXN
Interaction	SPICE1 interactions	MYH6 MAP7D3 POF1B HAUS4 DDX54 SERPINB2 TRIM37	5.66e-05	191	103	7	int:SPICE1
Interaction	RHOG interactions	SLC11A2 UACA DSG2 PMPCB TSC1 LRPPRC NUP155 TMEM9 BSG CD99 DDX54 MACF1 IMMT NOTCH1 GOLGA4	5.86e-05	910	103	15	int:RHOG
Interaction	YWHAE interactions	HDAC9 MAP7D3 ACD RCN2 APC TSC1 SRGAP2 ITGA2B NCOR2 FAM13A ARHGEF7 DDX54 MACF1 DLG4 SIPA1L2 CDC25C USP48 NIN	6.21e-05	1256	103	18	int:YWHAE
Interaction	NUP93 interactions	HDAC9 NUP155 ARHGAP31 BSG CENPI TLN2 CDC25C NIN	7.23e-05	269	103	8	int:NUP93
Interaction	SEPTIN10 interactions	CNOT10 APC SEPTIN8 PSME4 IMMT NIN	9.70e-05	144	103	6	int:SEPTIN10
Interaction	RFXANK interactions	HDAC9 BSG CHTF18 FBXO7 NPRL3 MAPRE2	1.05e-04	146	103	6	int:RFXANK
Interaction	SNW1 interactions	DDX19B DDX19A ARFGEF2 LRRC40 BTAF1 NCOR2 NUP155 CTNNBL1 USP48 TRIM37 MTUS2 NOTCH1 NIN	1.11e-04	747	103	13	int:SNW1
Interaction	ADH1C interactions	CPA4 POF1B SERPINB2	1.18e-04	19	103	3	int:ADH1C
Interaction	GSK3B interactions	MAP7D3 DSG2 APC TSC1 GFPT1 RNF220 HAUS4 FAM193A FBXO7 MACF1 SIPA1L2 USP48 NOTCH1 NIN	1.33e-04	868	103	14	int:GSK3B
Interaction	DNAJC5 interactions	UACA DSG2 SRGAP2 BSG CD99 MACF1 USP48 IMMT GOLGA4	1.39e-04	378	103	9	int:DNAJC5
Interaction	RPGRIP1L interactions	APC NUP155 DDX54 SIPA1L2 TRIM37 GOLGA4 NIN	1.57e-04	225	103	7	int:RPGRIP1L
Interaction	BCL6 interactions	HDAC9 POF1B NCOR2 FARSA CTNNBL1 USP48 MTUS2	1.75e-04	229	103	7	int:BCL6
Interaction	GJA1 interactions	MYH6 UACA DSG2 APC NUP155 BSG CD99 MACF1 SIPA1L2 NOTCH1 GOLGA4	1.94e-04	583	103	11	int:GJA1
Interaction	RHOC interactions	SLC11A2 DSG2 NUP155 TMEM9 BSG CD99 DDX54 MACF1 IMMT NOTCH1 GOLGA4	1.97e-04	584	103	11	int:RHOC
Interaction	DUSP16 interactions	RCN2 SRGAP2 HAUS4 KCTD20 NPRL3 SIPA1L2 TRIM37	2.16e-04	237	103	7	int:DUSP16
Interaction	COG4 interactions	APC FARSA NUP155 BSG TRIM37	2.32e-04	108	103	5	int:COG4
Interaction	PRICKLE1 interactions	SRGAP2 KMT5B ARHGEF7 DLG4	2.52e-04	60	103	4	int:PRICKLE1
Interaction	KRT38 interactions	CNOT10 APC TSC1 HAUS4 TRIM37 NIN	2.56e-04	172	103	6	int:KRT38
Interaction	SIPA1L1 interactions	SRGAP2 DLG4 SIPA1L2 CDC25C TRIM37 NIN	2.72e-04	174	103	6	int:SIPA1L1
Interaction	FTH1 interactions	CPA4 TSC1 POF1B CD99 DLG4 TRIM37	2.72e-04	174	103	6	int:FTH1
Interaction	PRICKLE2 interactions	SRGAP2 ARHGEF7 FBXO7 DLG4	2.86e-04	62	103	4	int:PRICKLE2
Interaction	ZYX interactions	DSG2 APC HIPK3 ARHGAP31 ARHGEF7 MACF1 TLN2 SIPA1L2	2.87e-04	329	103	8	int:ZYX
GeneFamily	Nucleoporins	DDX19B DDX19A NUP155	3.24e-04	32	76	3	1051
GeneFamily	DEAD-box helicases	DDX19B DDX19A DDX54	7.28e-04	42	76	3	499
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	SRGAP2 FAM13A ARHGAP31	1.21e-03	50	76	3	721
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEB2 POTEB	1.32e-03	13	76	2	685
GeneFamily	ATP binding cassette subfamily A	ABCA4 ABCA5	1.54e-03	14	76	2	805
GeneFamily	Ubiquitin specific peptidases	USP34 USP29 USP48	1.69e-03	56	76	3	366
GeneFamily	Myosin heavy chains	MYH6 MYH7B	1.77e-03	15	76	2	1098
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA2B ITGA7	2.55e-03	18	76	2	1160
GeneFamily	Ankyrin repeat domain containing	UACA POTEB2 KANK4 POTEB NOTCH1	3.52e-03	242	76	5	403
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	MYO7A ARFGEF2	6.58e-03	29	76	2	396
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	APC ITGA2B CDC25C HYDIN	7.12e-03	181	76	4	694
Coexpression	MURARO_PANCREAS_BETA_CELL	HDAC9 USP34 SLC11A2 GLIS3 APC ARFGEF2 SESN1 GFPT1 TGFBR3 NCOR2 LRPPRC BBX ABCA5 FBXO7 SIPA1L2 USP48 MAPRE2 TRIM37 MTUS2 GOLGA4 NIN	8.30e-11	946	102	21	M39169
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP34 SLC11A2 APC SRGAP2 BTAF1 TGFBR3 NCOR2 LRPPRC FAM193A BBX PSME4 ARHGEF7 PKD2 SERPINB2 MACF1 TRIM37 GOLGA4	3.33e-08	856	102	17	M4500
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	DDX19A SLC11A2 MAP7D3 DSG2 RCN2 APC ARFGEF2 LRRC40 TSC1 BTAF1 SESN1 HIPK3 LRPPRC FAM13A ARHGEF7 KCTD20 MACF1 GOLGA4	9.69e-07	1215	102	18	M41122
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN	COL11A1 TSC1 ITGA7 LRPPRC SERPINB2 DLG4 NOTCH1	1.36e-05	200	102	7	M9657
Coexpression	GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_UP	DDX19B SLC11A2 MYO7A SERPINB2 KCTD20 MAPRE2 GOLGA4	1.36e-05	200	102	7	M8605
Coexpression	ZENG_GU_ICB_CONTROL_METAGENE_31_PRECICTIVE_ICB_RESISTANCE	USP29 SLC22A17 GPR179 CITED4 FAM13A KANK4 CADPS2	1.40e-05	201	102	7	MM17086
Coexpression	HU_FETAL_RETINA_RPE	ABCA4 UACA DSG2 NCOR2 FAM13A BSG PRKCQ GOLGA4	1.86e-05	291	102	8	M39271
Coexpression	DESCARTES_MAIN_FETAL_ERYTHROBLASTS	SLC11A2 ABCB6 BSG CHTF18 CENPI FBXO7 NPRL3	4.97e-05	245	102	7	M40073
Coexpression	GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP	ITGA7 ABCA5 ARHGAP31 FBXO7 MACF1 NIN	5.31e-05	169	102	6	M6700
Coexpression	PEART_HDAC_PROLIFERATION_CLUSTER_UP	SESN1 SEPTIN8 CDC25C MAPRE2	5.47e-05	53	102	4	M1409
Coexpression	GSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_DN	ITGA7 TGFBR3 ARHGAP31 CTNNBL1 DLG4 SIPA1L2	9.29e-05	187	102	6	M6691
Coexpression	GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP	ACD MYO7A TGFBR3 HAUS4 TMEM9 IMMT	1.14e-04	194	102	6	M4213
Coexpression	GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP	HDAC9 RCN2 ARFGEF2 BTAF1 RNF220 TLN2	1.27e-04	198	102	6	M5018
Coexpression	GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP	JADE3 WDR19 WDR91 RNF220 ARHGEF7 CTNNBL1	1.27e-04	198	102	6	M3249
Coexpression	HALLMARK_MITOTIC_SPINDLE	APC TSC1 LRPPRC ARHGEF7 PKD2 NIN	1.31e-04	199	102	6	M5893
Coexpression	GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_UP	USP34 HDHD5 RCN2 CD99 CENPI TRIM37	1.34e-04	200	102	6	M9584
Coexpression	GSE27786_LIN_NEG_VS_NKTCELL_UP	ABCB6 SEPTIN8 FARSA CITED4 NUP155 TMEM9	1.34e-04	200	102	6	M4787
Coexpression	GSE1460_DP_VS_CD4_THYMOCYTE_UP	RAG1 WDR19 ARHGEF7 CD99 FBXO7 CTNNBL1	1.34e-04	200	102	6	M3452
Coexpression	PILON_KLF1_TARGETS_UP	COL11A1 MYH7B ITGA2B WDR19 TGFBR3 CITED4 TMEM9 KMT5B PKD2	1.55e-04	503	102	9	M2226
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 ZNF407 BTAF1 TGFBR3 ABCA5 MACF1 GOLGA4	4.12e-07	199	103	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	droplet-Marrow-BM-30m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 ABCB6 SEPTIN8 CITED4 TMEM9 PRKCQ	3.55e-06	177	103	6	650095a17e1a39caea74a6e89646565b9332af5d
ToppCell	droplet-Marrow-BM-30m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 ABCB6 SEPTIN8 CITED4 TMEM9 PRKCQ	3.55e-06	177	103	6	d1af0cb4b1fb03f04cff5add85e29be8fb8f4dcb
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC11A2 RNF220 FAM13A KANK4 PRKCQ CADPS2	3.79e-06	179	103	6	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	droplet-Marrow-nan-21m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 ABCB6 SEPTIN8 CITED4 TMEM9 FBXO7	4.72e-06	186	103	6	6e6998f5ccb1b2628048a21e8d3053e020569aba
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 ZNF407 BTAF1 FAM13A MACF1 MAPRE2	5.02e-06	188	103	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC11A2 GFPT1 FAM13A KANK4 PRKCQ CADPS2	5.02e-06	188	103	6	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	droplet-Marrow-BM-30m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 ABCB6 SEPTIN8 CITED4 TMEM9 FBXO7	5.02e-06	188	103	6	f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCell	droplet-Marrow-nan-24m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 ABCB6 SEPTIN8 CITED4 TMEM9 FBXO7	5.17e-06	189	103	6	98ace332c3c046694c6ade47de8c8bf57ec51271
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 MYH6 MYH7B ITGA7 FRY MTUS2	5.33e-06	190	103	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	droplet-Marrow-BM-1m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 ABCB6 SEPTIN8 CITED4 TMEM9 FBXO7	5.50e-06	191	103	6	d78d4fbb0b8317dbf14e32182466a432abef3e93
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 DSG2 POF1B PSME4 KMT5B GOLGA4	5.50e-06	191	103	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UACA SRGAP2 ARHGAP31 SIPA1L2 CADPS2 MAPRE2	5.83e-06	193	103	6	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UACA SRGAP2 ARHGAP31 SIPA1L2 CADPS2 MAPRE2	5.83e-06	193	103	6	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	SLC11A2 FAM13A ABCA5 KANK4 PRKCQ CADPS2	6.56e-06	197	103	6	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLC11A2 FAM13A ABCA5 KANK4 PRKCQ CADPS2	6.75e-06	198	103	6	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	Control_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets\|Control_saline / Treatment groups by lineage, cell group, cell type	HDAC9 ITGA2B CD99 KCTD20 PRKCQ IMMT	6.95e-06	199	103	6	86d4e5dd3bcc6bafa48fd0211dad39a2456b53be
ToppCell	droplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT3 KCTD20 CTNNBL1 KANK4 SIPA1L2	4.33e-05	167	103	5	a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 MYH6 MYH7B FRY MTUS2	4.71e-05	170	103	5	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	UACA TGFBR3 PKD2 MACF1 TLN2	5.41e-05	175	103	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 MYO7A ABCB6 CHTF18 CENPI	5.56e-05	176	103	5	3766e0533b103ec92ac75eba3df02e287efc53fa
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DSG2 ABCB6 B3GNT3 POF1B SERPINB2	5.56e-05	176	103	5	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 MYH6 ITGA7 FRY MTUS2	5.56e-05	176	103	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 MYO7A ABCB6 CHTF18 CENPI	5.56e-05	176	103	5	aa1bada2175d8370fc71939a607407155259d195
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 UACA B3GNT3 NCOR2 PKD2	6.02e-05	179	103	5	55bc69f107fc710db7617c428575792adfdbbcc1
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 B3GNT3 TGFBR3 FRY PKD2	6.18e-05	180	103	5	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DSG2 TGFBR3 CD99 PRKCQ PDZD4	6.34e-05	181	103	5	12ff56fa2949c8d53360cdf2cacfd326e65b54aa
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 MYH6 MYH7B FRY MTUS2	6.34e-05	181	103	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ABCB6 TSC1 PSME4 BSG FBXO7	6.51e-05	182	103	5	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175\|Adult / Lineage, Cell type, age group and donor	CPA4 UACA ITGA2B TGFBR3 SIPA1L2	6.51e-05	182	103	5	8b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 UACA B3GNT3 CLSTN1 NCOR2	6.68e-05	183	103	5	83592c332b1e82673f993d37c7f480befdc3dcda
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RNF220 FAM13A KANK4 PRKCQ CADPS2	6.86e-05	184	103	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 MYH6 MYH7B FRY MTUS2	7.04e-05	185	103	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HDAC9 UACA ITGA7 FRY KANK4	7.40e-05	187	103	5	b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 GLIS3 WDR91 PRKCQ HYDIN	7.59e-05	188	103	5	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	MYH6 MYH7B SESN1 FRY MTUS2	7.78e-05	189	103	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UACA TGFBR3 FRY ARHGAP31 CADPS2	7.78e-05	189	103	5	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	facs-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UACA B3GNT3 ARHGAP31 TRIM37 NOTCH1	7.78e-05	189	103	5	f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCell	facs-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UACA B3GNT3 ARHGAP31 TRIM37 NOTCH1	7.78e-05	189	103	5	e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCell	facs-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UACA B3GNT3 ARHGAP31 TRIM37 NOTCH1	7.78e-05	189	103	5	5559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCell	facs-SCAT-Fat-3m-Endothelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UACA B3GNT3 FRY ARHGAP31 TRIM37	8.18e-05	191	103	5	a0018f88f7132477cc467ee15db029a585290595
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 DSG2 POF1B PSME4 KMT5B	8.18e-05	191	103	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	facs-SCAT-Fat-3m-Endothelial-endothelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UACA B3GNT3 FRY ARHGAP31 TRIM37	8.18e-05	191	103	5	6b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCell	facs-SCAT-Fat-3m-Endothelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UACA B3GNT3 FRY ARHGAP31 TRIM37	8.18e-05	191	103	5	90f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 DSG2 POF1B PSME4 KMT5B	8.18e-05	191	103	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	droplet-Marrow-BM-1m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB6 SEPTIN8 TMEM9 FBXO7 PRKCQ	8.38e-05	192	103	5	ced2fdbcb181ac250ff50cd4d5d886e568924203
ToppCell	droplet-Marrow-BM-1m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB6 SEPTIN8 TMEM9 FBXO7 PRKCQ	8.38e-05	192	103	5	19b8675ed8a99bd3d08ad043e4ec9f006426c22f
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UACA SRGAP2 ARHGAP31 SIPA1L2 CADPS2	8.59e-05	193	103	5	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	MYH6 MYH7B FRY MAPRE2 MTUS2	8.80e-05	194	103	5	c3535f7cc0076653c72db582047cff053c322397
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A B3GNT3 TGFBR3 ARHGAP31 NOTCH1	9.01e-05	195	103	5	12ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell	facs-Heart-RA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT3 FRY ARHGAP31 TRIM37 NOTCH1	9.01e-05	195	103	5	f4fdcc0b851392086e9618e76ee6a0b540d5fb3c
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TGFBR3 CD99 MACF1 PRKCQ PDZD4	9.23e-05	196	103	5	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	UACA TGFBR3 ARHGAP31 SIPA1L2 CADPS2	9.23e-05	196	103	5	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBR3 CD99 MACF1 PRKCQ PDZD4	9.23e-05	196	103	5	c100967851f037b3522130a9e2a4175ad593ecbc
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	UACA TGFBR3 FRY SIPA1L2 CADPS2	9.23e-05	196	103	5	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 BTAF1 MACF1 PRKCQ GOLGA4	9.46e-05	197	103	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 DSG2 CLSTN1 SERPINB2 HYDIN	9.46e-05	197	103	5	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TGFBR3 MACF1 MAPRE2 NOTCH1 PDZD4	9.69e-05	198	103	5	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / Treatment groups by lineage, cell group, cell type	SLC11A2 FAM13A KANK4 PRKCQ CADPS2	9.69e-05	198	103	5	d087e738d69ca9853553fde46d4e7a8906439d32
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TGFBR3 MACF1 MAPRE2 NOTCH1 PDZD4	9.69e-05	198	103	5	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	Influenza-Influenza_Severe-Others-RBC\|Influenza_Severe / Disease, condition lineage and cell class	SLC11A2 ABCB6 BSG FBXO7 TLN2	9.92e-05	199	103	5	da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 UACA MACF1 NOTCH1 NIN	1.02e-04	200	103	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-CD4+_CTL\|ICU-NoSEP / Disease, condition lineage and cell class	TGFBR3 CD99 MACF1 PRKCQ PDZD4	1.02e-04	200	103	5	c470520ce77130811fdc2a1d3d796d8836275de1
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 LRRC40 ITGA7 PKD2 KANK4	1.02e-04	200	103	5	5ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 UACA TGFBR3 FRY PKD2	1.02e-04	200	103	5	b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	UACA WDR91 TGFBR3 PKD2 TLN2	1.02e-04	200	103	5	251fd2923f108cd2086961d897244b392c32ad54
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 UACA TGFBR3 FRY PKD2	1.02e-04	200	103	5	7c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABCA4 MYH7B GABRQ FAM193A	1.38e-04	113	103	4	79ba2eb8f85e5da4c19c838df881c18ffdc450fb
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABCA4 MYH7B GABRQ FAM193A	1.38e-04	113	103	4	91d55fe6fb1c1472867d74461f5b9e4f17db01cd
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABCA4 MYH7B GABRQ FAM193A	1.38e-04	113	103	4	34ae3dec5ec7585d155ea61de6adc42aa4f45226
Drug	Tropicamide [1508-75-4]; Down 200; 14uM; HL60; HT_HG-U133A	SRGAP2 GFPT1 ZFX SEPTIN8 PSME4 NPRL3 MACF1 MAPRE2	2.77e-06	199	100	8	2347_DN
Disease	Atrial Septal Defects	MYH6 GABRQ	1.11e-04	5	99	2	C0018817
Disease	cortical surface area measurement	CPA4 HDAC9 USP34 COL11A1 GLIS3 APC CLSTN1 HAUS4 FAM13A ARHGAP31 MACF1 TLN2 CDC25C MAPRE2	1.58e-04	1345	99	14	EFO_0010736
Disease	Adams Oliver syndrome	ARHGAP31 NOTCH1	1.66e-04	6	99	2	C0265268
Disease	Congenital defect of skull and scalp	ARHGAP31 NOTCH1	1.66e-04	6	99	2	C2931779
Disease	Adams-Oliver syndrome 1	ARHGAP31 NOTCH1	1.66e-04	6	99	2	C4551482
Disease	Adams-Oliver syndrome (is_implicated_in)	ARHGAP31 NOTCH1	1.66e-04	6	99	2	DOID:0060227 (is_implicated_in)
Disease	Angle Closure Glaucoma	COL11A1 GLIS3	2.31e-04	7	99	2	C0017605
Disease	retinal degeneration (is_implicated_in)	ABCA4 PKD2	3.95e-04	9	99	2	DOID:8466 (is_implicated_in)
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH6 MYH7B	4.93e-04	10	99	2	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH6 MYH7B	4.93e-04	10	99	2	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH6 MYH7B	4.93e-04	10	99	2	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH6 MYH7B	4.93e-04	10	99	2	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH6 MYH7B	4.93e-04	10	99	2	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH6 MYH7B	4.93e-04	10	99	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH6 MYH7B	4.93e-04	10	99	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH6 MYH7B	4.93e-04	10	99	2	DOID:0080326 (implicated_via_orthology)
Disease	Ciliopathies	MYO7A TSC1 WDR19 PKD2	5.24e-04	110	99	4	C4277690
Disease	primary angle closure glaucoma	COL11A1 GLIS3	6.01e-04	11	99	2	EFO_1001506
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	COL11A1 USP48	6.01e-04	11	99	2	DOID:0050564 (is_implicated_in)
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRQ NCOR2 DLG4	6.03e-04	49	99	3	DOID:0060037 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH6 MYH7B	7.20e-04	12	99	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH6 MYH7B	7.20e-04	12	99	2	DOID:2106 (implicated_via_orthology)
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL11A1 PKD2 NOTCH1	7.60e-04	53	99	3	C4707243
Disease	pulse pressure measurement	HDAC9 USP34 MYH6 COL11A1 SLC22A17 TGFBR3 FAM193A FAM13A NPRL3 TLN2 HYDIN GOLGA4 NIN	7.69e-04	1392	99	13	EFO_0005763
Disease	loneliness measurement	HDAC9 FAM180B ARFGEF2 MACF1	8.22e-04	124	99	4	EFO_0007865
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH6 MYH7B	8.48e-04	13	99	2	DOID:397 (implicated_via_orthology)
Disease	Connective Tissue Diseases	PKD2 NOTCH1	8.48e-04	13	99	2	C0009782
Disease	Neoplasm of uncertain or unknown behavior of bladder	TSC1 NOTCH1	1.14e-03	15	99	2	C0496930
Disease	Benign neoplasm of bladder	TSC1 NOTCH1	1.14e-03	15	99	2	C0154017
Disease	distal arthrogryposis (implicated_via_orthology)	MYH6 MYH7B	1.14e-03	15	99	2	DOID:0050646 (implicated_via_orthology)
Disease	Carcinoma in situ of bladder	TSC1 NOTCH1	1.14e-03	15	99	2	C0154091
Disease	hyperinsulinism (biomarker_via_orthology)	GFPT1 PRKCQ	1.14e-03	15	99	2	DOID:2018 (biomarker_via_orthology)
Disease	osteoarthritis, hip, osteoarthritis, knee	COL11A1 GLIS3 TGFBR3	1.20e-03	62	99	3	EFO_0004616, EFO_1000786
Disease	cognitive function measurement, self reported educational attainment	COL11A1 ARFGEF2 BTAF1 LRPPRC FAM193A TRIM37	1.27e-03	355	99	6	EFO_0004784, EFO_0008354
Disease	peak expiratory flow	COL11A1 GLIS3 TGFBR3 FRY HAUS4 FAM13A NPRL3	1.46e-03	498	99	7	EFO_0009718
Disease	Carcinoma of bladder	TSC1 NOTCH1	1.65e-03	18	99	2	C0699885
Disease	autism spectrum disorder (implicated_via_orthology)	TSC1 KMT5B DLG4 CADPS2	1.74e-03	152	99	4	DOID:0060041 (implicated_via_orthology)
Disease	erythrocyte measurement	USP34 FBXO7 NPRL3 TLN2 USP48	1.77e-03	257	99	5	EFO_0005047
Disease	cardiomyopathy (implicated_via_orthology)	MYH6 MYH7B ITGA7	1.77e-03	71	99	3	DOID:0050700 (implicated_via_orthology)
Disease	Osteoarthritis of hip	HDAC9 COL11A1	2.04e-03	20	99	2	C0029410
Disease	cancer (implicated_via_orthology)	ITGA7 KANK4 MACF1 DLG4 NOTCH1	2.13e-03	268	99	5	DOID:162 (implicated_via_orthology)
Disease	dyslexia	CPA4 HDAC9 ARFGEF2 POF1B	2.20e-03	162	99	4	EFO_0005424
Disease	Splenomegaly	APC NOTCH1	2.46e-03	22	99	2	C0038002
Disease	response to peginterferon alfa-2a	HDAC9 GLIS3	3.18e-03	25	99	2	EFO_0010103
Disease	aggressive behavior	ARFGEF2 HIPK3	3.18e-03	25	99	2	EFO_0003015

Protein segments in the cluster

Peptide	Gene	Start	Entry
IAQVMHLEDFNEGAS	ABCA5	371	Q8WWZ7
SHEQVLEEMLEAGLD	CHTF18	346	Q8WVB6
ALAEVAAMENVHRGQ	BBX	901	Q8WY36
EADGVHNTLAIVENM	CTNNBL1	211	Q8WYA6
LDGDVNELMDVVLHH	ABCA4	1201	P78363
EEALQMLSGGDEDHD	CTSL3P	186	Q5NE16
EDAEHMVAAQQDTLD	ARFGEF2	1576	Q9Y6D5
VEAAAQAAGIHDAIM	ABCB6	696	Q9NP58
GTDLMHNHVLADDDQ	ARHGEF7	736	Q14155
QGEVDMESHRNANAE	CD99	161	P14209
GEELNHEQESLEVDM	CLSTN1	726	O94985
DTEVVANMNGIHSEL	FAM193A	316	P78312
LQFEAEMARLQEEHG	MTUS2	1106	Q5JR59
QGIAQEEALHLIDEM	RCN2	261	Q14257
EEALHLIDEMDLNGD	RCN2	266	Q14257
NEHRQADELEAIMQG	RAG1	446	P15918
LMLLEHGADGNIQDE	POTEB2	186	H3BUK9
DMAGAQAAAVALNEE	DSG2	756	Q14126
QLDLELEIENMGAHL	PMPCB	116	O75439
EMVEEAEALHASGNE	NCOR2	716	Q9Y618
GQDEEELFHSIRMDN	PRKCQ	581	Q04759
AVEGMLEDLINSHAD	NOTCH1	2006	P46531
RAGENEMDAEDAHHQ	GPR179	1041	Q6PRD1
MEAQHNDLEFKLAGA	GOLGA4	1921	Q13439
AGDDVLEDQEILMHH	KCTD20	381	Q7Z5Y7
DDNGNAIHMTEELHI	GABRQ	216	Q9UN88
EIEENMLLRHGENDF	KMT5B	236	Q4FZB7
HAREIQLFMVDNGAD	KCNN1	161	Q92952
QQAAGAVLDLMGDEA	DDX54	706	Q8TDD1
RHTEGMQADADDNIL	COL11A1	1556	P12107
DNMNDGEELIATDHA	MYH7B	366	A7E2Y1
ALDVNRNESLGHEMA	PDZD4	386	Q76G19
LALQDEVSAMADGNE	NPRL3	171	Q12980
RAHQEQLDEMAELGF	KIF24	1296	Q5T7B8
CDVQGLEHDMEEINA	MACF1	1436	O94854
AAEGKLHNMIVDLDN	IMMT	326	Q16891
GHARAGDMENAENIL	LRPPRC	241	P42704
VAVFQDVEHLTGMND	SLC11A2	426	P49281
DMVDILNRTGHQLAD	ASIC4	161	Q96FT7
SELHDNQDGLVNMES	FAM13A	476	O94988
LENGLNADEHMANTD	HIPK3	1001	Q9H422
ELGHLQNDMTSLEND	POF1B	341	Q8WVV4
QMLEEDSNQGHLIGD	CDC25C	271	P30307
GILLMAASENEDNDI	NUP155	416	O75694
DNDMEDLVAAALVDH	HYDIN	3641	Q4G0P3
EQEAGVLAMDALHRQ	BTAF1	1481	O14981
ALGDLHAANQMEEFA	DNAH3	1726	Q8TD57
FEAESIQDNAHMAEG	FBXO7	146	Q9Y3I1
ALLDNEDDEMQHNEG	CPA4	96	Q9UI42
EDGALEHERMQQLEH	GLIS3	231	Q8NEA6
LDEADVMIATQGHQD	DDX19B	241	Q9UMR2
NHEQMGLLRDEALAE	DDX11L8	321	A8MPP1
GRSELHIENLNMEAD	BSG	281	P35613
LAELMEHSENGAVID	CADPS2	696	Q86UW7
VLNGDDDVFAHTDNM	B3GNT3	206	Q9Y2A9
NSVGLEDVMHEDAVA	DLG4	216	P78352
EHGQENDDLVQRLMD	MAPRE2	281	Q15555
DMAKEAVGGQAEDHL	MAP7D3	636	Q8IWC1
DVNLQDHDGSSALMV	KANK4	921	Q5T7N3
QADGDDAHEAQLLVM	ITGA7	746	Q13683
MDDELRHIAQNSLQG	FRY	636	Q5TBA9
HLEEAEEELQGDQAM	HDAC9	501	Q9UKV0
LEGAIHLQEQDMENS	HAUS4	306	Q9H6D7
HADDQAEEDALQMAV	CENPI	56	Q92674
DEADVMIATQGHQDQ	DDX19A	241	Q9NUU7
ENMNHAIETEEGLGI	JADE3	181	Q92613
HVGENQIEMLEAEHL	LRRC40	271	Q9H9A6
HQAMVDVNEEGTEAA	SERPINB2	356	P05120
DVMGQLHIQDEELAS	FAM180B	61	Q6P0A1
HLEGLQMTDLENNSE	TRIM37	866	O94972
EILQVGSEDAQMHAL	SESN1	56	Q9Y6P5
LDSAELAAELGMEHQ	FARSA	21	Q9Y285
HGQMLGEEAQEALQD	SLC22A17	266	Q8WUG5
QQDMDLDIEFDVHLG	GFPT1	76	Q06210
LQNVDGEMLEEVFHN	NIN	216	Q8N4C6
LEQQHVGLAVDMDEI	NBPF10	2371	Q6P3W6
LMLLEHGADGNIQDE	POTEB	186	A0A0A6YYL3
GLMEASHVVNDVNEA	HDHD5	396	Q9BXW7
TDMQHGQDLEGAQEL	SIPA1L2	1616	Q9P2F8
TNQLIDHLLGENDGM	WDR19	1071	Q8NEZ3
CMAEDDAVDIEHENN	RNF220	336	Q5VTB9
VLELQMDAANEGEGA	ITGA2B	661	P08514
EGDLNEMEIQLSHAN	MYH6	1621	P13533
LLDEMREDQEHQGAL	ACD	171	Q96AP0
ANHMDDNDGELDTPI	APC	1011	P25054
AHALGGMDAELIDEE	CITED4	126	Q96RK1
KNQVHSAVEEMDGLD	CNOT10	91	Q9H9A5
GAQENHDDLMSVVVF	UHRF1BP1L	1181	A0JNW5
LHNEEENEDARSMAA	TMEM9	126	Q9P0T7
MEVLDRLIQQGADAH	TSC1	646	Q92574
GDQNDHDMDSIAGVL	SRGAP2	551	O75044
VAEIFSGNMQNDAHE	USP29	361	Q9HBJ7
DEAVAEINAVMNAHL	SEPTIN8	221	Q92599
AVLLHEMDEDDLANA	ARHGAP31	636	Q2M1Z3
GDQELTEHEHQQMRD	PKD2	766	Q13563
IQNHVMEENGIGEED	PSME4	1551	Q14997
AAQGHMDEDVQEALL	UACA	1391	Q9BZF9
AAAAAAVHEQQMDDN	ZFX	336	P17010
MHAVQQAQDDLSELD	TLN2	506	Q9Y4G6
QEAQGEHMDLVESDG	ZNF407	2126	Q9C0G0
ADHDDQDVVLFNRGM	USP34	2836	Q70CQ2
EGEENEALHKMIANE	USP48	701	Q86UV5
AADGVIRLFDMQQHE	WDR91	581	A4D1P6
FHLRLENNAEEMGDE	TGFBR3	351	Q03167
ENNAEEMGDEEVHTI	TGFBR3	356	Q03167
HIEFTDNQDALDMIA	MYO7A	486	Q13402