Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24

6.06e-10371668GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24

7.62e-10381668GO:0070001
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 SGIP1 ERVK-7 ERVK-10 REV3L ERVK-8 PRIMPOL

2.46e-08381667GO:0034061
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 SGIP1 ERVK-7 ERVK-10 ERVK-8

7.04e-08141665GO:0003964
GeneOntologyMolecularFunctionGTPase activator activity

DOCK1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IQGAP1 TBC1D3I ARHGAP20 TBC1D3G TBCD TBC1D3K TBC1D3F

9.24e-0827916614GO:0005096
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.45e-06111664GO:0004523
GeneOntologyMolecularFunctionAMPA glutamate receptor activity

GRIA1 GRIA2 GRIA3

2.24e-0641663GO:0004971
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK1 TBC1D3 PSD TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IQGAP1 TBC1D3I ARHGAP20 TBC1D3G VAV2 TBCD TBC1D3K TBC1D3F

5.36e-0650716616GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK1 TBC1D3 PSD TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IQGAP1 TBC1D3I ARHGAP20 TBC1D3G VAV2 TBCD TBC1D3K TBC1D3F

5.36e-0650716616GO:0030695
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TNIK ERVK-6 AKT3 SGIP1 NT5C3A TSSK2 DGKD ERVK-7 PFKFB3 ALPK1 ERVK-10 REV3L MYO3A GUCY2C ERVK-8 PIP5K1A AKT2 TSSK1B MAP4K4 EIF2AK2 STK24 PRIMPOL

1.10e-0593816622GO:0016772
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 RAG1 SMARCA5 ERCC3 SGIP1 ERVK-7 ERVK-10 REV3L THAP9 ERVK-8 PRIMPOL

1.26e-0526216611GO:0140097
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.47e-05211664GO:0035613
GeneOntologyMolecularFunctionionotropic glutamate receptor binding

GRIA1 GRIA2 NEDD4 SHANK2 PICK1

7.08e-05521665GO:0035255
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.46e-04371664GO:0016891
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 SGIP1 ERVK-7 ERVK-10 REV3L ERVK-8 PRIMPOL

2.85e-041521667GO:0016779
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA1 GRIA2 GRIA3

3.52e-04171663GO:0004970
GeneOntologyMolecularFunctionenzyme activator activity

DOCK1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IQGAP1 PSME3 TBC1D3I ARHGAP20 TBC1D3G TBCD TBC1D3K TBC1D3F

3.91e-0465616615GO:0008047
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DYNC2H1 DNAH17

4.20e-04181663GO:0008569
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

5.73e-04461664GO:0016893
GeneOntologyMolecularFunctionglutamate receptor binding

GRIA1 GRIA2 NEDD4 SHANK2 PICK1

5.75e-04811665GO:0035254
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TNIK AKT3 NT5C3A TSSK2 DGKD PFKFB3 ALPK1 MYO3A GUCY2C PIP5K1A AKT2 TSSK1B MAP4K4 EIF2AK2 STK24

8.69e-0470916615GO:0016773
GeneOntologyMolecularFunctionprotein serine kinase activity

TNIK AKT3 TSSK2 ALPK1 MYO3A AKT2 TSSK1B MAP4K4 EIF2AK2 STK24

9.44e-0436316610GO:0106310
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ADAMTS19 CD46 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 PLAU ERVK-24

9.68e-0443016611GO:0004175
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 RAG1 TSN ERVK-7 ERVK-10 ERVK-8

9.73e-041361666GO:0004519
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA1 GRIA2 GRIA3

1.00e-03241663GO:0099507
GeneOntologyMolecularFunctionpeptidase activity

ERVK-6 ADAMTS19 USP25 CD46 ERVK-7 ERVK-21 ERVK-9 ERVK-10 STAMBP ERVK-8 PAN2 ERVK-19 PLAU ERVK-24

1.16e-0365416614GO:0008233
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-6 RPS17 ERVK-7 ERVK-21 ERVK-9 ERVK-10 OGN MRPL35 SHANK2 TLN1 ERVK-8 ERVK-5 ERVK-19 MACROH2A2 ERVK-24 EPB41L2 MYBPC1

1.24e-0389116617GO:0005198
GeneOntologyMolecularFunctionzinc ion binding

MORC1 ERVK-6 RAG1 ESRRB ERVK-7 ERVK-21 ERVK-9 ERVK-10 PHF5A RXRB ZCRB1 ERVK-8 ERVK-5 KMT2A ERVK-19 ERVK-24 PRIMPOL

1.24e-0389116617GO:0008270
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA1 GRIA2 GRIA3

1.43e-03271663GO:0008066
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DYNC2H1 DNAH17

1.59e-03281663GO:0051959
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIA1 GRIA3

1.86e-0381662GO:0022849
GeneOntologyMolecularFunctionPH domain binding

INPP5A EPB41L2

2.38e-0391662GO:0042731
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 RAG1 SMARCA5 ERCC3 SGIP1 NT5C3A ERVK-7 ERVK-10 REV3L THAP9 ERVK-8 PAN2 PRIMPOL

2.92e-0364516613GO:0140640
GeneOntologyMolecularFunctionbeta-2 adrenergic receptor binding

GRIA1 NEDD4

2.96e-03101662GO:0031698
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 RAG1 TSN ERVK-7 ERVK-10 ERVK-8 PAN2

3.25e-032311667GO:0004518
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PIP5K1A AKT2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

6.38e-1110916312GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PIP5K1A AKT2 GRHL3 TBC1D3I TBC1D3G MAP4K4 TBC1D3K TBC1D3F

9.16e-0924416314GO:0043547
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IQGAP1 PIP5K1A AKT2 GRHL3 TBC1D3I TBC1D3G MAP4K4 VAV2 TBC1D3K TBC1D3F

1.05e-0833516316GO:0043087
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 THAP9 ERVK-8

3.54e-08131635GO:0015074
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 REV3L SYCP1 ERVK-8 PRIMPOL

9.49e-08481637GO:0000731
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PIP5K1A AKT2 PSME3 GRHL3 TBC1D3I TBC1D3G MAP4K4 CREB3 TBC1D3K TBC1D3F

2.29e-0649916316GO:0051345
GeneOntologyBiologicalProcessviral process

ERVK-6 CD46 ERVK-7 ERVK-21 ERVK-9 ERVK-10 NEDD4 HAVCR1 SLC20A2 ERVK-8 ERVK-5 ERVK-19 ERVK-24 EIF2AK2 CREB3

4.37e-0646416315GO:0016032
GeneOntologyBiologicalProcesscell-cell fusion

DOCK1 ERVK-6 ERVK-21 ERVK-9 NEO1 ERVK-8 ERVK-19

4.98e-06851637GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

DOCK1 ERVK-6 ERVK-21 ERVK-9 NEO1 ERVK-8 ERVK-19

4.98e-06851637GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

DOCK1 ERVK-6 ERVK-21 ERVK-9 NEO1 ERVK-8 ERVK-19

6.77e-06891637GO:0006949
GeneOntologyBiologicalProcessregulation of hydrolase activity

RAG1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IQGAP1 PIP5K1A AKT2 PSME3 GRHL3 TBC1D3I TBC1D3G MAP4K4 VAV2 CREB3 TBC1D3K TBC1D3F

6.78e-0587816319GO:0051336
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

TBC1D3 TBC1D3H TBC1D3L TBC1D3D SSBP1 TBC1D3C TBC1D3B AXIN2 IQGAP1 FSHR PIP5K1A AKT2 PSME3 GRHL3 TBC1D3I TBC1D3G MAP4K4 CREB3 TBC1D3K TBC1D3F

1.83e-04102816320GO:0043085
GeneOntologyCellularComponentdendritic spine

PSD GRIA1 GRIA2 GRIA3 NLGN1 TENM2 NEDD4 DIP2A SHANK2 PICK1

2.22e-0524216410GO:0043197
GeneOntologyCellularComponentneuron spine

PSD GRIA1 GRIA2 GRIA3 NLGN1 TENM2 NEDD4 DIP2A SHANK2 PICK1

2.64e-0524716410GO:0044309
GeneOntologyCellularComponentruffle membrane

PSD FERMT1 TLN1 PIP5K1A AKT2 PLCG2

2.10e-041081646GO:0032587
GeneOntologyCellularComponentleading edge membrane

PSD FERMT1 GRIA1 GRIA2 TLN1 PIP5K1A AKT2 PLCG2

2.60e-042101648GO:0031256
GeneOntologyCellularComponentperisynaptic space

GRIA1 GRIA2

3.63e-0441642GO:0099544
GeneOntologyCellularComponentcell projection membrane

PSD FERMT1 GRIA1 GRIA2 SHANK2 SLC20A2 TLN1 PIP5K1A AKT2 PLCG2 ABCC2

6.16e-0443116411GO:0031253
DomainTBC

TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

2.42e-10491569SM00164
DomainRabGAP-TBC

TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

5.08e-10531569PF00566
DomainRab-GTPase-TBC_dom

TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

7.19e-10551569IPR000195
DomainTBC_RABGAP

TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

7.19e-10551569PS50086
DomainPumilio_RNA-bd

PUM2 PUM1

6.93e-0521562IPR033712
DomainNHL

NHLRC2 TENM2 TENM4

1.54e-04131563PS51125
DomainRhs_assc_core

TENM2 TENM4

2.07e-0431562IPR022385
DomainPUF

PUM2 PUM1

2.07e-0431562PF00806
DomainPUM_HD

PUM2 PUM1

2.07e-0431562PS50303
DomainPUM-HD

PUM2 PUM1

2.07e-0431562IPR033133
DomainSYCP1/2

SYCP2 SYCP1

2.07e-0431562IPR024835
DomainANF_lig-bd_rcpt

GRIA1 GRIA2 GRIA3 GUCY2C

2.50e-04371564IPR001828
DomainANF_receptor

GRIA1 GRIA2 GRIA3 GUCY2C

2.50e-04371564PF01094
Domain-

SAMD9 DGKD SAMD15 SFMBT2 SHANK2 SPDEF

2.64e-0410615661.10.150.50
DomainPeripla_BP_I

GRIA1 GRIA2 GRIA3 GUCY2C

3.07e-04391564IPR028082
DomainTox-GHH_dom

TENM2 TENM4

4.11e-0441562IPR028916
DomainTox-GHH

TENM2 TENM4

4.11e-0441562PF15636
DomainPUM

PUM2 PUM1

4.11e-0441562PS50302
DomainPumilio_RNA-bd_rpt

PUM2 PUM1

4.11e-0441562IPR001313
DomainTen_N

TENM2 TENM4

4.11e-0441562IPR009471
DomainTen_N

TENM2 TENM4

4.11e-0441562PF06484
DomainTENEURIN_N

TENM2 TENM4

4.11e-0441562PS51361
DomainPumilio

PUM2 PUM1

4.11e-0441562SM00025
DomainLig_chan-Glu_bd

GRIA1 GRIA2 GRIA3

4.25e-04181563PF10613
DomainGlu/Gly-bd

GRIA1 GRIA2 GRIA3

4.25e-04181563IPR019594
DomainLig_chan-Glu_bd

GRIA1 GRIA2 GRIA3

4.25e-04181563SM00918
DomainIontro_rcpt

GRIA1 GRIA2 GRIA3

4.25e-04181563IPR001320
DomainIono_rcpt_met

GRIA1 GRIA2 GRIA3

4.25e-04181563IPR001508
DomainLig_chan

GRIA1 GRIA2 GRIA3

4.25e-04181563PF00060
DomainPBPe

GRIA1 GRIA2 GRIA3

4.25e-04181563SM00079
DomainSAM_2

SAMD9 DGKD SAMD15 SFMBT2

4.49e-04431564PF07647
DomainSAM/pointed

SAMD9 DGKD SAMD15 SFMBT2 SHANK2 SPDEF

4.50e-041171566IPR013761
Domain-

AKT3 PSD FERMT1 DGKD NIBAN2 TLN1 AKT2 PLCG2 ARHGAP20 VAV2 EPB41L2

4.55e-04391156112.30.29.30
DomainPH

AKT3 PSD FERMT1 DGKD NIBAN2 AKT2 PLCG2 ARHGAP20 VAV2

5.59e-042781569SM00233
DomainPH_DOMAIN

AKT3 PSD FERMT1 DGKD NIBAN2 AKT2 PLCG2 ARHGAP20 VAV2

5.74e-042791569PS50003
DomainPH_domain

AKT3 PSD FERMT1 DGKD NIBAN2 AKT2 PLCG2 ARHGAP20 VAV2

5.89e-042801569IPR001849
DomainYD

TENM2 TENM4

6.82e-0451562IPR006530
DomainSAM

SAMD9 DGKD SAMD15 SFMBT2 SHANK2

8.55e-04881565SM00454
Domainzf-CCHC

ERVK-6 ZCRB1 ERVK-5

8.95e-04231563PF00098
DomainPH_dom-like

AKT3 PSD FERMT1 DGKD NIBAN2 TLN1 AKT2 PLCG2 ARHGAP20 VAV2 EPB41L2

9.23e-0442615611IPR011993
DomainSAM_DOMAIN

SAMD9 DGKD SAMD15 SFMBT2 SHANK2

1.21e-03951565PS50105
DomainSAM

SAMD9 DGKD SAMD15 SFMBT2 SHANK2

1.32e-03971565IPR001660
DomainPkinase

TNIK AKT3 TSSK2 MYO3A GUCY2C AKT2 TSSK1B MAP4K4 EIF2AK2 STK24

1.39e-0338115610PF00069
DomainCAMSAP_CH

ASPM VAV2

1.42e-0371562PF11971
DomainCAMSAP_CH

ASPM VAV2

1.42e-0371562IPR022613
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K

1.96e-06991208M46448
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

GRIA1 GRIA2 GRIA3 PICK1

8.40e-06161204MM15048
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

GRIA1 GRIA2 GRIA3 PICK1

1.09e-05171204M5488
PathwayWP_NRXN1_DELETION_SYNDROME

GRIA1 GRIA2 GRIA3 NLGN1

1.39e-05181204M48098
PathwayREACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY

AKT3 AKT2 CDH5 VAV2

7.53e-05271204M27422
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

GRIA1 GRIA2 GRIA3 PICK1

1.01e-04291204MM15028
PathwayREACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY

AKT3 AKT2 CDH5 VAV2

1.15e-04301204MM15170
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

GRIA1 GRIA2 GRIA3 PICK1

1.32e-04311204M7223
PathwayREACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY

AKT3 PSMF1 NEDD4 AKT2 PSME3

2.99e-04691205MM15540
PathwayREACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY

AKT3 PSMF1 NEDD4 AKT2 PSME3

2.99e-04691205M27815
PathwayREACTOME_CYCLIN_A_CDK2_ASSOCIATED_EVENTS_AT_S_PHASE_ENTRY

AKT3 PSMF1 CCNA1 AKT2 PSME3

3.20e-04701205MM15389
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

5.43e-23111671016863688
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

5.13e-104167410469592
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10 ERVK-5 ERVK-19

5.13e-10416747983737
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-5 ERVK-19 ERVK-24

8.19e-1094167921542922
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SMARCA5 ERCC3 MTHFD1L FERMT1 RPS17 DGKD SSBP1 ZBED5 IQGAP1 ZC3H7A VPS33B FDPS TLN1 PES1 RPF2 NCAPD2 ASPM WDR82 MACROH2A2 PRR14L PSME3 PLCG2 IK PUM1 EIF2AK2 EPB41L2

1.75e-0913531672629467282
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

1.85e-0912167514557543
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21 ERVK-19

2.55e-095167412629516
Pubmed

AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.

GRIA1 GRIA2 GRIA3

1.09e-073167334426577
Pubmed

Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage.

GRIA1 GRIA2 GRIA3

1.09e-073167315144856
Pubmed

Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase.

GRIA1 GRIA2 GRIA3

1.09e-073167312700243
Pubmed

Subunit-specific role for the amino-terminal domain of AMPA receptors in synaptic targeting.

GRIA1 GRIA2 GRIA3

1.09e-073167328630296
Pubmed

NMDAR-dependent presynaptic homeostasis in adult hippocampus: Synapse growth and cross-modal inhibitory plasticity.

GRIA1 GRIA2 GRIA3

1.09e-073167336070750
Pubmed

An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain.

GRIA1 GRIA2 GRIA3

1.09e-073167332569783
Pubmed

Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex.

GRIA1 GRIA2 GRIA3

1.09e-073167336223737
Pubmed

Persistent synaptic scaling independent of AMPA receptor subunit composition.

GRIA1 GRIA2 GRIA3

1.09e-073167323864664
Pubmed

AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy.

GRIA1 GRIA2 GRIA3

1.09e-073167315145077
Pubmed

Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain.

GRIA1 GRIA2 GRIA3

1.09e-073167328290985
Pubmed

Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain.

GRIA1 GRIA2 GRIA3

1.09e-073167326585043
Pubmed

Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors.

GRIA1 GRIA2 GRIA3

1.09e-073167314687553
Pubmed

Synaptic homeostasis requires the membrane-proximal carboxy tail of GluA2.

GRIA1 GRIA2 GRIA3

1.09e-073167329180434
Pubmed

Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach.

GRIA1 GRIA2 GRIA3

1.09e-073167319409270
Pubmed

Synaptic targeting of AMPA receptors is regulated by a CaMKII site in the first intracellular loop of GluA1.

GRIA1 GRIA2 GRIA3

1.09e-073167321135237
Pubmed

LTP requires a reserve pool of glutamate receptors independent of subunit type.

GRIA1 GRIA2 GRIA3

1.09e-073167323235828
Pubmed

The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.

GRIA1 GRIA2 GRIA3 PICK1

2.46e-0712167411891216
Pubmed

AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.

GRIA1 GRIA2 GRIA3

4.33e-07416739221927
Pubmed

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

GRIA1 GRIA2 GRIA3

4.33e-074167325337787
Pubmed

Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.

GRIA1 GRIA2 GRIA3

4.33e-074167317828255
Pubmed

The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.

GRIA1 GRIA2 GRIA3

4.33e-074167324652293
Pubmed

Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

GRIA2 GRIA3 PICK1

4.33e-074167310027300
Pubmed

AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.

GRIA1 GRIA2 GRIA3

4.33e-074167312692557
Pubmed

Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.

GRIA1 GRIA2 GRIA3

4.33e-074167312125045
Pubmed

The cell-autonomous role of excitatory synaptic transmission in the regulation of neuronal structure and function.

GRIA1 GRIA2 GRIA3

4.33e-074167323664612
Pubmed

The Role of AMPARs in the Maturation and Integration of Caudal Ganglionic Eminence-Derived Interneurons into Developing Hippocampal Microcircuits.

GRIA1 GRIA2 GRIA3

4.33e-074167330931998
Pubmed

LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes.

GRIA1 GRIA2 GRIA3

4.33e-074167329581259
Pubmed

Distribution of alpha-amino-3-hydroxy-5-methyl-4 isoazolepropionic acid and N-methyl-D-aspartate receptor subunits in the vestibular and spiral ganglia of the mouse during early development.

GRIA1 GRIA2 GRIA3

4.33e-074167312414093
Pubmed

A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.

GRIA1 GRIA2 GRIA3

4.33e-074167310688364
Pubmed

GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons.

GRIA1 GRIA2 GRIA3

4.33e-074167326932439
Pubmed

Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development.

GRIA1 GRIA2 GRIA3

4.33e-074167331231192
Pubmed

Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.

GRIA1 GRIA2 GRIA3

4.33e-074167317409242
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3 TBC1D3D TBC1D3F

4.33e-074167312359748
Pubmed

AMPA receptor deletion in developing MGE-derived hippocampal interneurons causes a redistribution of excitatory synapses and attenuates postnatal network oscillatory activity.

GRIA1 GRIA2 GRIA3

4.33e-074167331992779
Pubmed

Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.

GRIA1 GRIA2 GRIA3

4.33e-074167314561864
Pubmed

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.

GRIA1 GRIA2 GRIA3

4.33e-074167332831170
Pubmed

Cortactin regulates endo-lysosomal sorting of AMPARs via direct interaction with GluA2 subunit.

GRIA1 GRIA2 GRIA3

4.33e-074167329515177
Pubmed

Chromosomal localization of human glutamate receptor genes.

GRIA1 GRIA2 GRIA3

4.33e-07416731319477
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3 TBC1D3D TBC1D3F

4.33e-07416738406013
Pubmed

AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62.

GRIA1 GRIA2 GRIA3

4.33e-074167319004011
Pubmed

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

GRIA1 GRIA2 GRIA3

4.33e-07416739648857
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMARCA5 CUX2 GRIA1 RPS17 GRIA2 GRIA3 PHF5A SFMBT2 IQGAP1 ZC3H7A SHANK2 TNN PES1 UNC5C RPF2 NCAPD2 SYCP1 ASPM KMT2A SPDEF ABCC2 PICK1 MYBPC1

4.64e-0714421672335575683
Pubmed

PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.

GRIA1 GRIA2 GRIA3 PICK1

8.92e-0716167416055064
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C

1.08e-065167312604796
Pubmed

Phase Separation-Mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission.

GRIA1 GRIA2 GRIA3

1.08e-065167331492534
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7 ERVK-5

1.08e-065167311401426
Pubmed

Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

GRIA1 GRIA2 GRIA3

1.08e-065167316129400
Pubmed

PI3K-Akt signaling pathway upregulates hepatitis C virus RNA translation through the activation of SREBPs.

AKT3 SREBF2 AKT2

1.08e-065167326855332
Pubmed

Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition.

RAG1 AKT3 AKT2

1.08e-065167317442925
Pubmed

The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking.

GRIA2 GRIA3 PICK1

1.08e-065167322445342
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3 TBC1D3D TBC1D3F

1.08e-06516738471161
Pubmed

An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline.

PUM2 SYCP1 PUM1

1.08e-065167327170441
Pubmed

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.

GRIA1 GRIA2 GRIA3

1.08e-06516739482932
Pubmed

Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF.

GRIA2 GRIA3 PICK1

1.08e-065167315797551
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

GLT8D2 RGSL1 SGIP1 GRIA1 REEP3 OGN CC2D2B IGSF10 TC2N VPS33B HECW2 SLC35B4 SYCP1 PAN2 SPDEF

1.26e-066861671529987050
Pubmed

Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice.

GRIA1 GRIA2 GRIA3 PICK1

1.49e-0618167434455539
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

GRIA1 GRIA2 GRIA3 PICK1

1.49e-0618167414730302
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-10 ERVK-24

1.49e-0618167418664271
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F

1.58e-0674167616625196
Pubmed

Mossy Cells Control Adult Neural Stem Cell Quiescence and Maintenance through a Dynamic Balance between Direct and Indirect Pathways.

GRIA1 GRIA2 GRIA3

2.15e-066167330057205
Pubmed

PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression.

GRIA2 GRIA3 PICK1

2.15e-066167323918399
Pubmed

Genetic inhibition of neurotransmission reveals role of glutamatergic input to dopamine neurons in high-effort behavior.

GRIA1 GRIA2 GRIA3

2.15e-066167328194005
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

2.15e-066167315063128
Pubmed

Glutamate receptor δ2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells.

GRIA1 GRIA2 GRIA3

3.75e-067167321368048
Pubmed

Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.

GRIA1 GRIA2 GRIA3

3.75e-067167333981040
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA1 GRIA2 GRIA3

3.75e-06716739016303
Pubmed

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.

GRIA1 GRIA2 GRIA3

3.75e-067167317093100
Pubmed

TARP γ-2 and γ-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area.

GRIA1 GRIA2 GRIA3

3.75e-067167327076426
Pubmed

Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo.

AKT3 AKT2 PLCG2

3.75e-067167317634444
Pubmed

CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus.

GRIA1 GRIA2 GRIA3

3.75e-067167320185686
Pubmed

Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.

GRIA1 GRIA2 GRIA3

3.75e-067167310407040
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA1 GRIA2 GRIA3

3.75e-06716739651535
Pubmed

Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.

GRIA1 GRIA2 GRIA3

5.98e-068167323217150
Pubmed

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets.

GRIA1 GRIA2 GRIA3

8.94e-069167324292102
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA1 GRIA2 GRIA3

8.94e-06916739051806
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

TNIK GRIA1 GRIA2 GRIA3 NLGN1 IQGAP1 NEDD4 SHANK2 EPB41L2

9.49e-06281167928706196
Pubmed

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.

CUX2 GRIA1 GRIA2 GRIA3 NEO1

1.06e-0560167532027825
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19

1.27e-0510167312970426
Pubmed

Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo.

GRIA1 GRIA2 PICK1

1.27e-0510167327800545
Pubmed

Common variants associated with general and MMR vaccine-related febrile seizures.

CD46 IFI44L ANO3

1.27e-0510167325344690
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

SMARCA5 ERCC3 MTHFD1L IQGAP1 ABCB10 VPS33B NCAPD2 PIP5K1A IK PUM1 EPB41L2 TBCD

1.85e-055601671235241646
Pubmed

A proteome-scale map of the SARS-CoV-2-human contactome.

DDIT4L USP25 KLC4 THAP9 AKAP9 MACROH2A2 EIF2AK2

2.16e-05173167736217029
Pubmed

Akt2 and Akt3 play a pivotal role in malignant gliomas.

AKT3 AKT2

2.29e-052167220167810
Pubmed

Amyloid-β effects on synapses and memory require AMPA receptor subunit GluA3.

GRIA1 GRIA3

2.29e-052167227708157
Pubmed

Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.

GRIA1 GRIA2

2.29e-052167221383497
Pubmed

Motor Learning Requires Purkinje Cell Synaptic Potentiation through Activation of AMPA-Receptor Subunit GluA3.

GRIA1 GRIA3

2.29e-052167228103481
Pubmed

Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.

PUM2 PUM1

2.29e-052167212459267
Pubmed

Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.

PUM2 PUM1

2.29e-052167229165587
Pubmed

A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A.

GRIA1 GRIA2

2.29e-052167214555717
Pubmed

PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression.

PUM2 PUM1

2.29e-052167235507203
Pubmed

Bespoke RNA recognition by Pumilios.

PUM2 PUM1

2.29e-052167226517885
Pubmed

Synaptic transmission and plasticity in the absence of AMPA glutamate receptor GluR2 and GluR3.

GRIA2 GRIA3

2.29e-052167212848940
Pubmed

Mouse Pum1 and Pum2 genes, members of the Pumilio family of RNA-binding proteins, show differential expression in fetal and adult hematopoietic stem cells and progenitors.

PUM2 PUM1

2.29e-052167212667987
InteractionGRIA1 interactions

TNIK GRIA1 GRIA2 GRIA3 NEDD4 EPB41L2 PICK1

5.77e-06861617int:GRIA1
InteractionEAF1 interactions

SREBF2 IQGAP1 TC2N ASPM PSME3 GRHL3 PICK1 TAF1D

8.85e-061281618int:EAF1
InteractionGRIA4 interactions

GRIA1 GRIA2 GRIA3 IQGAP1 PICK1

1.82e-05411615int:GRIA4
InteractionGRIA3 interactions

TNIK GRIA1 GRIA2 GRIA3 PICK1

2.30e-05431615int:GRIA3
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

2.06e-1014916610chr17q12
Cytoband17q12

TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F

3.16e-0599166517q12
Cytoband2p22-p21

PUM2 EIF2AK2

3.59e-04816622p22-p21
GeneFamilyGlutamate ionotropic receptor AMPA type subunits

GRIA1 GRIA2 GRIA3

5.25e-0749331200
GeneFamilySterile alpha motif domain containing

SAMD9 DGKD SAMD15 SFMBT2 SHANK2

9.04e-0588935760
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AKT3 PSD FERMT1 DGKD AKT2 VAV2

6.81e-04206936682
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FERMT1 TLN1 EPB41L2

2.17e-03509331293
CoexpressionHEVNER_CORTICAL_PLATE_POSTMITOTIC_PROJECTION_NEURONS

TNIK TTC39B AKT3 SGIP1 GRIA3 NLGN1 TENM2 NEO1

3.05e-061471578MM414
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

2.35e-08901589PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#2_top-relative-expression-ranked_200

DOCK1 DGKD REV3L SIM2 TENM2 AKAP9 ZCRB1 PLAU

3.05e-07881588gudmap_developingKidney_e15.5_200_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#1_top-relative-expression-ranked_1000

DOCK1 PUM2 DGKD REV3L IQGAP1 AKAP9 ZCRB1 PLAU EIF2AK2

6.09e-061731589gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k1
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

TTC39B TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

1.41e-0524215810PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_200

DOCK1 DGKD REV3L SIM2 TENM2 AKAP9 ZCRB1 PLAU

2.15e-051551588gudmap_developingKidney_e15.5_anlage of loop of Henle_200
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D DDIT4L TBC1D3C TBC1D3B PLCG2 TBC1D3G TBC1D3K TBC1D3F

2.89e-0532015811PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

3.21e-052131589PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

3.21e-052131589PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TNIK TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

5.02e-0528115810PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TNIK TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

5.02e-0528115810PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_500

DOCK1 CUX2 DDIT4L GRIA1 DGKD REV3L OGN UNC5C ZCRB1 PLAU ARHGAP20 EPB41L2

6.26e-0541215812gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

EGLN3 AKT3 TBC1D3 TBC1D3H TBC1D3L TBC1D3D ZFYVE16 HGSNAT DDIT4L DGKD NLGN1 TBC1D3C TBC1D3B RXRB AXIN2 DIP2A NEO1 AKAP9 TOX3 PAN2 PLAU TBC1D3G CCDC136 TBC1D3K TBC1D3F

8.32e-05146615825PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#1_top-relative-expression-ranked_100

REV3L SIM2 ZCRB1 PLAU

1.29e-04351584gudmap_developingKidney_e15.5_100_k1
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

EGLN3 TBC1D3 TBC1D3H TBC1D3L TBC1D3D ZFYVE16 DDIT4L DGKD NLGN1 TBC1D3C TBC1D3B RXRB NEO1 TOX3 PAN2 PLAU TBC1D3G CCDC136 TBC1D3K TBC1D3F

1.47e-04107515820PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500

DOCK1 AKT3 DGKD REV3L SIM2 TENM2 AKAP9 TMEM72 ZCRB1 PLAU EIF2AK2

2.19e-0440215811gudmap_developingKidney_e15.5_anlage of loop of Henle_500
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#2_top-relative-expression-ranked_100

DOCK1 REV3L ZCRB1

2.55e-04171583gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100_k2
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#3_top-relative-expression-ranked_200

DOCK1 REV3L ZCRB1 PLAU

2.91e-04431584gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200_k3
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS19 SEC16B GLT8D2 NLGN1 OGN GLP2R IGSF10 UNC5C EPB41L2

3.30e-081941589439d3f17c1f4736122b330e98add9292c7036a8e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 SGIP1 DDIT4L OGN NEDD4 IGSF10 AKAP9 PLAU ARHGAP20

3.45e-0819515895c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

ADAMTS19 GLT8D2 NLGN1 OGN GLP2R IGSF10 UNC5C EPB41L2

4.43e-071921588a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TNIK SGIP1 GRIA1 TENM2 TENM4 UNC5C ARHGAP20 VAV2

4.79e-07194158835f132cc38ac133be01834ed0946188aa0757eb4
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DYNC2H1 GRIA1 ALPK1 REV3L OGN IGSF10 ARHGAP20 EPB41L2

5.38e-071971588fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DYNC2H1 ALPK1 REV3L OGN IGSF10 AKAP9 ARHGAP20 EPB41L2

6.03e-0720015889b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK AKT3 SAMD9 TC2N AKAP9 KMT2A IFI44L EIF2AK2

6.03e-072001588109f673a4967ffa52270a0b4f818b3461288db44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB TSSK2 SIM2 TENM4 TMEM72 PLAU

3.11e-061751587e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CUX2 SHANK2 TOX3 ABCC2 PUM1 MAP4K4 VAV2

4.48e-0618515871d874608aa2062024323512f68889219471b2f00
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGLN3 INPP5A NEDD4 HECW2 IFI44L EIF2AK2 CDH5

4.81e-061871587f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGLN3 SFMBT2 NEDD4 HECW2 TOX3 IFI44L CDH5

4.81e-061871587dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

SGIP1 ESRRB SIM2 HAVCR1 TENM4 SHANK2 TMEM72

5.53e-061911587fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EGLN3 AKT3 DYNC2H1 REV3L TC2N UNC5C EPB41L2

5.53e-06191158770c067c54084bfb02c29bab085f4defd477194fb
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS19 GLT8D2 NLGN1 OGN GLP2R IGSF10 UNC5C

5.72e-061921587e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB DDIT4L SIM2 AKAP9 TMEM72 PLAU

5.72e-061921587ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RGSL1 SLC26A5 MYO3A GUCY2C SYCP1 SPDEF ABCC2

5.92e-061931587315840bc48899f3a36d57b19197509de19716e3d
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK TTC39B AKT3 TC2N AKAP9 IFI44L PLCG2

5.92e-0619315879337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK1 EGLN3 AKT3 SFMBT2 HECW2 TOX3 CDH5

6.12e-0619415870b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK TTC39B AKT3 TC2N AKAP9 KMT2A PLCG2

6.77e-06197158757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellcontrol-Myeloid-Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SAMD9 NT5C3A TMEM154 ALPK1 IFI44L FYB1 EIF2AK2

6.77e-0619715878819db1550bf14566c6d33d97f7f83419e867ace
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TNIK GRIA1 NLGN1 OGN IGSF10 UNC5C ARHGAP20

6.77e-0619715870034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK TTC39B AKT3 DIP2A TC2N AKAP9 IFI44L

7.23e-061991587f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMARCA5 SAMD9 AKAP9 KMT2A IFI44L PLCG2 EIF2AK2

7.47e-06200158712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

OGN AXIN2 NEO1 UNC5C ANO3 EPB41L2

2.75e-051651586e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

OGN AXIN2 NEO1 UNC5C ANO3 EPB41L2

2.75e-051651586b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

OGN AXIN2 NEO1 UNC5C ANO3 EPB41L2

2.75e-051651586d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FERMT1 RFX7 KLC4 NCAPD2 WDR82 MACROH2A2

3.47e-051721586c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FERMT1 RFX7 KLC4 NCAPD2 WDR82 MACROH2A2

3.47e-051721586bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MORC1 RGSL1 MYO3A SPDEF ABCC2

3.48e-051041585b5ca6e589f414e549f4990fe334d4ee54829b298
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAMD9 NT5C3A TMEM154 MACROH2A2 IFI44L EIF2AK2

3.83e-05175158697616bb5c127284aa9e67bc336dfcf29e137164b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 NLGN1 PFKFB3 SIM2 SHANK2 DNAH17

4.08e-051771586da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

SEC16B SAMD9 NT5C3A TTC21A IFI44L EIF2AK2

4.21e-051781586ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 TENM4 TMEM72 PLAU

4.21e-0517815864df6218b20c2f076c22346d23260964cc0d73e65
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FERMT1 GRIA3 SIM2 TOX3 SPDEF MYBPC1

4.34e-051791586859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FERMT1 GRIA3 SIM2 TOX3 SPDEF MYBPC1

4.48e-0518015863dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FERMT1 GRIA3 SIM2 TOX3 SPDEF MYBPC1

4.48e-051801586668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell10x5'-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

TTC39B TSSK2 TMEM154 ALPK1 ASPM CCNA1

4.62e-05181158656fa77ae31f3b7de6e441a439c33a11353b6573a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 ESRRB TMEM72 SLC35B4 UNC5C TOX3

4.76e-0518215865f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SEC16B GLT8D2 TBC1D3 DDIT4L GRIA2 NEDD4

4.76e-05182158600a148b1e499bf16325491536d187d4dd6b70c06
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 ESRRB TMEM72 SLC35B4 UNC5C TOX3

4.91e-0518315862e831a4d99c6f983793df71c0994124c943c6da9
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EGLN3 SIDT1 GRIA2 CC2D2B PLCG2 CDH5

5.06e-051841586a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 TENM4 SHANK2 TMEM72

5.06e-051841586e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Tuft-Tuft|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS19 TOX3 MACROH2A2 PLCG2 GRHL3 MYBPC1

5.21e-0518515861fbdc96da0623c3935ae9d29dcb4ba9c474e5c21
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Tuft|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS19 TOX3 MACROH2A2 PLCG2 GRHL3 MYBPC1

5.21e-051851586b45487daac116e3d3d65ac2b0f81d1bf7d1a1914
ToppCellCOPD-Lymphoid-B|COPD / Disease state, Lineage and Cell class

INPP5A SIDT1 SREBF2 TMEM154 PLCG2 MAP4K4

5.21e-051851586925e79c35c381dd44ec5fb921dca09ce43140135
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFYVE16 GRIA1 PFKFB3 TC2N KMT2A CDH5

5.37e-05186158639e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZFYVE16 GRIA1 PFKFB3 TC2N KMT2A CDH5

5.37e-05186158602418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

SGIP1 ESRRB TSSK2 SIM2 TENM4 TMEM72

5.53e-0518715862ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

NLGN1 HAVCR1 SHANK2 TMEM72 TOX3 ABCC2

5.53e-051871586d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

INPP5A HECW2 PLAU CDH5 STK24 EPB41L2

5.70e-0518815861aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLT8D2 GRIA1 OGN IGSF10 UNC5C ARHGAP20

5.87e-051891586a153b83314cf52808f685296cff8c95af3f4983d
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 AKT3 SGIP1 ESRRB PFKFB3 SIM2

5.87e-051891586830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ADAMTS19 EGLN3 AKT3 DYNC2H1 TC2N UNC5C

6.04e-05190158612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS19 PSD MTHFD1L NLGN1 SFMBT2 EPB41L2

6.04e-0519015860fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 TENM4 TMEM72 PLAU

6.04e-0519015863dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 TENM4 SHANK2 TMEM72

6.04e-051901586cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 ESRRB TMEM72 SLC35B4 UNC5C TOX3

6.04e-051901586e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 TENM4 SHANK2 TMEM72

6.22e-051911586963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK SMARCA5 OGN NEDD4 PLAU ARHGAP20

6.22e-0519115867d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

SGIP1 ESRRB SIM2 TENM4 SHANK2 TMEM72

6.22e-0519115860965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TBC1D3H ESRRB RPS17 SHANK2 IFI44L

6.37e-051181585f76fc6db7368a1e8e5e4f8535fc3dc78afe13b9b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBC1D3H ESRRB RPS17 SHANK2 IFI44L

6.37e-0511815850dcac16eea8e7978de370a815da9a0cdd212598e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBC1D3H ESRRB RPS17 SHANK2 IFI44L

6.37e-0511815857da3957d102e9f9825fc2609d6d0bd9ca6a3fba4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TBC1D3H ESRRB RPS17 SHANK2 IFI44L

6.37e-051181585c5c6724e0e526d7c2fc8cabff4a112a900ec997f
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS19 NLGN1 OGN GLP2R IGSF10 EPB41L2

6.40e-0519215868d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIA1 GRIA3 OGN IGSF10 NEO1 UNC5C

6.40e-05192158625492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DOCK1 AKT3 DYNC2H1 TENM4 UNC5C EPB41L2

6.40e-05192158660b1312e84f6d6448365a952469c506c00b5fe93
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIA1 GRIA3 OGN IGSF10 NEO1 UNC5C

6.40e-051921586de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS19 TSN TOX3 MACROH2A2 GRHL3 MYBPC1

6.59e-0519315865879efb38e6b3bf8c33c9a773632b1d726e3c153
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGLN3 SFMBT2 NEDD4 HECW2 TOX3 CDH5

6.59e-051931586e1d546165dcc2392f540162206852c4717d7306f
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS19 GLT8D2 NLGN1 GLP2R IGSF10 UNC5C

6.59e-0519315869ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS19 TSN TOX3 MACROH2A2 GRHL3 MYBPC1

6.59e-051931586725115a5ce3ef520b3ef469e96b8219b4c723fdd
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS19 TSN TOX3 MACROH2A2 GRHL3 MYBPC1

6.59e-051931586abd7bcf318a2d895d8811c2ada8bfb4314fca3b1
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTS19 AKAP9 TOX3 PLCG2 PUM1 MAP4K4

6.59e-051931586e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellControl-Lymphoid_T/NK-CD4+_T_activated|Control / Disease group, lineage and cell class

TBC1D3H ESRRB RPS17 SHANK2 IFI44L

6.63e-051191585d7352d0dafbb664619b7a1e3cd07b159fdfec197
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TNIK SGIP1 GRIA1 TENM2 UNC5C ARHGAP20

6.78e-051941586011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGLN3 AKT3 NEDD4 HECW2 TOX3 CDH5

6.78e-05194158643f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGIP1 GRIA1 OGN IGSF10 UNC5C ARHGAP20

6.78e-05194158660622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellcontrol-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SAMD9 NT5C3A ALPK1 IFI44L FYB1 EIF2AK2

6.78e-051941586267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGLN3 AKT3 NEDD4 HECW2 TOX3 CDH5

6.78e-0519415861d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGLN3 SFMBT2 NEDD4 HECW2 TOX3 CDH5

6.78e-05194158658f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EGLN3 SFMBT2 NEDD4 HECW2 TOX3 CDH5

6.78e-051941586bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK NT5C3A IGSF10 TC2N TLN1 FYB1

6.78e-051941586216cba1a04b1a24b080322bc950e7fa2dade5ff1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTS19 GRIA1 NLGN1 OGN UNC5C ARHGAP20

6.98e-05195158670387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIA1 GRIA3 OGN IGSF10 NEO1 UNC5C

6.98e-0519515863a0cad69cfc150a27a0666f612f5294c817197d7
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

AKT3 DYNC2H1 TENM4 TC2N UNC5C EPB41L2

6.98e-051951586f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SGIP1 NLGN1 TENM2 NEO1 UNC5C ARHGAP20

6.98e-0519515860e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIA1 GRIA3 OGN IGSF10 NEO1 UNC5C

6.98e-0519515862b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

TTC39B SAMD9 NT5C3A USP25 IFI44L EIF2AK2

6.98e-051951586b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

AKT3 DYNC2H1 REV3L TC2N UNC5C EPB41L2

6.98e-051951586ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 AKAP9 TMEM72 PLAU

7.18e-0519615861bfc3c85ce9501f52a912e53cbded7de74572b9d
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK NT5C3A IGSF10 TC2N TLN1 FYB1

7.18e-05196158666ba31b74953726e9c314f6d8fe3f75d3762e23a
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TNIK NLGN1 OGN UNC5C ARHGAP20 EPB41L2

7.18e-0519615861450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 AKAP9 TMEM72 PLAU

7.18e-051961586e02301642243df483fd066d978317c113c04692b
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

AKT3 MTHFD1L REV3L TC2N UNC5C ANO3

7.18e-051961586e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS19 GLT8D2 NLGN1 TENM2 TENM4 IFI44L

7.38e-0519715866806ec223e542f0475303698eb78c1cc527f5c6b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 AKAP9 TMEM72 PLAU

7.38e-0519715864ea3f57cd88b8a6bb7cb4b9e3545c0fa8f331886
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 AKAP9 TMEM72 PLAU

7.59e-051981586688b0eb5534dde40b8630ab8a3252c816711e02e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 ESRRB SIM2 AKAP9 TMEM72 PLAU

7.59e-0519815864448d13511485a44fe7b549e4b8b6ad7637db624
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TNIK NLGN1 OGN UNC5C ARHGAP20 EPB41L2

7.59e-05198158617dc055e2a289496d9c5cdbf3297bdf906dc6d22
Drug3-pyridazinol 1-oxide

GRIA1 GRIA2 GRIA3

1.21e-0641543CID000574311
DrugAC1L1YEG

GRIA1 GRIA2 GRIA3

3.00e-0651543CID000063114
DrugChicago acid

GRIA1 GRIA2 GRIA3

3.00e-0651543CID000065740
DrugCHEBI:570577

GRIA1 GRIA2 GRIA3

3.00e-0651543CID011334126
Drug1-BCP

GRIA1 GRIA2 GRIA3

3.00e-0651543CID000001370
Drugirampanel

GRIA1 GRIA2 GRIA3

3.00e-0651543CID003038472
DrugLY395153

GRIA1 GRIA2 GRIA3

3.00e-0651543CID000656707
Drugbeta-N-oxalylaminoalanine

GRIA1 GRIA2 GRIA3

3.00e-0651543CID000107978
Drug5-h PCA

GRIA1 GRIA2 GRIA3

3.00e-0651543CID000129091
DrugYM928

GRIA1 GRIA2 GRIA3

5.98e-0661543CID006918393
Drug2cmo

GRIA1 GRIA2 GRIA3

5.98e-0661543CID006914597
Drug4,6-dichloroindole-2-carboxylic acid

GRIA1 GRIA2 GRIA3

1.04e-0571543CID000127988
Drugthio-ATPA

GRIA1 GRIA2 GRIA3

1.04e-0571543CID005289517
Drughomoibotenic acid

GRIA1 GRIA2 GRIA3

1.66e-0581543CID000194385
Drug1-hydroxypyrazole

GRIA1 GRIA2 GRIA3

1.66e-0581543CID003016733
Drug1-hydroxyimidazole

GRIA1 GRIA2 GRIA3

1.66e-0581543CID003614351
Drug2,3-PDCA

GRIA1 GRIA2 GRIA3

1.66e-0581543CID000127037
DrugM100907

GRIA1 GRIA2 GRIA3 CD46 PHF5A

2.42e-05511545CID000060858
Drug1m5b

GRIA1 GRIA2 GRIA3

2.47e-0591543CID000447081
DrugLy294486

GRIA1 GRIA2 GRIA3

2.47e-0591543CID005311255
Drugisothiazol-3-one

GRIA1 GRIA2 GRIA3

2.47e-0591543CID000096917
DrugBenzoates

GRIA1 GRIA2 GRIA3

3.52e-05101543ctd:D001565
Drug2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid

GRIA1 GRIA2

4.55e-0521542ctd:C474829
Drug4-bromohomoibotenic acid

GRIA1 GRIA2

4.55e-0521542ctd:C023366
Drug5-fluorowillardiine

GRIA1 GRIA3

4.55e-0521542ctd:C095178
DrugMeasles-Mumps-Rubella Vaccine

CD46 IFI44L

4.55e-0521542ctd:D022542
Druggeldanamycin

AKT3 INPP5A USP25 GRIA3 RFX7 IQGAP1 DIP2A ASPM KMT2A PLAU PRR14L

4.67e-0537115411ctd:C001277
DrugAC1L32TU

GRIA1 GRIA2 GRIA3 GRHL3

4.81e-05301544CID000107831
DrugJ-ST

GRIA1 GRIA2 GRIA3

4.81e-05111543CID005288655
DrugYM872

GRIA1 GRIA2 GRIA3

4.81e-05111543CID000148200
Drug0-ol

GRIA1 GRIA2 GRIA3

4.81e-05111543CID000069892
Drugsym 2206

GRIA1 GRIA2 GRIA3

4.81e-05111543CID005039877
DrugAtpa

GRIA1 GRIA2 GRIA3

6.38e-05121543CID000002252
Drug1NaPP1

GRIA1 GRIA2 GRIA3

6.38e-05121543CID000004877
DrugC-X6

GRIA1 GRIA2 GRIA3

6.38e-05121543CID005288002
Drugpafuramidine

HAVCR1 PIP5K1A EIF2AK2

6.38e-05121543ctd:C458513
Drug6,7-dinitroquinoxaline

GRIA1 GRIA2 GRIA3 GRHL3

7.07e-05331544CID002724608
DrugD-CPPene

GRIA1 GRIA2 GRIA3 CD46

7.97e-05341544CID006435801
DrugNaspm

GRIA1 GRIA2 GRIA3

8.26e-05131543CID000129695
Drugquinoxaline-2,3-dione

GRIA1 GRIA2 GRIA3

1.05e-04141543CID011469229
Drugthiokynurenic acid

GRIA1 GRIA2 GRIA3

1.30e-04151543CID003035667
Drugnonanol

GRIA1 GRIA3 ABCC2

1.30e-04151543CID000008914
DiseaseArsenic Induced Polyneuropathy

TNIK ERCC3 INPP5A SSBP1 PFKFB3 AKAP9 TAF1D

2.46e-08621467C0751852
DiseaseArsenic Encephalopathy

TNIK ERCC3 INPP5A SSBP1 PFKFB3 AKAP9 TAF1D

2.46e-08621467C0751851
DiseaseArsenic Poisoning

TNIK ERCC3 INPP5A SSBP1 PFKFB3 AKAP9 TAF1D

2.46e-08621467C0311375
DiseaseArsenic Poisoning, Inorganic

TNIK ERCC3 INPP5A SSBP1 PFKFB3 AKAP9 TAF1D

2.46e-08621467C0274861
DiseaseNervous System, Organic Arsenic Poisoning

TNIK ERCC3 INPP5A SSBP1 PFKFB3 AKAP9 TAF1D

2.46e-08621467C0274862
Diseasecentral nervous system disease (implicated_via_orthology)

SMARCA5 GRIA1 GRIA2 GRIA3

1.00e-06161464DOID:331 (implicated_via_orthology)
DiseaseDermatologic disorders

TNIK INPP5A SSBP1 PFKFB3 AKAP9 TAF1D

2.01e-06751466C0037274
Diseasehair colour measurement

TNIK CUX2 ZFYVE16 PUM2 REV3L PKD1L3 AXIN2 NEO1 TENM4 TOX3 EPB41L2 TBCD

5.89e-0561514612EFO_0007822
DiseaseFebrile seizure (within the age range of 3 months to 6 years), MMR-related febrile seizures

CD46 IFI44L

7.27e-0531462EFO_0006519, HP_0002373
DiseaseC-C motif chemokine 3 measurement

GRIA1 TBC1D3B PLCG2

9.17e-05181463EFO_0008051
DiseaseBipolar Disorder

CUX2 GRIA1 GRIA2 GRIA3 NLGN1 PFKFB3 NEDD4 TENM4 SHANK2 AKT2

1.39e-0447714610C0005586
Diseasestatus epilepticus (biomarker_via_orthology)

GRIA1 GRIA2 NLGN1 PLAU ABCC2

1.43e-041001465DOID:1824 (biomarker_via_orthology)
Disease7-methylxanthine measurement

DOCK1 PFKFB3

1.45e-0441462EFO_0021176
Diseaseprostate cancer (is_implicated_in)

NAT1 AKT3 SREBF2 CCNA1 AKT2

2.97e-041171465DOID:10283 (is_implicated_in)
DiseasePsychosexual Disorders

GRIA1 GRIA3

3.60e-0461462C0033953
DiseaseHypoactive Sexual Desire Disorder

GRIA1 GRIA3

3.60e-0461462C0020594
DiseaseSexual Arousal Disorder

GRIA1 GRIA3

3.60e-0461462C0036902
DiseaseFrigidity

GRIA1 GRIA3

3.60e-0461462C0016722
DiseaseOrgasmic Disorder

GRIA1 GRIA3

3.60e-0461462C0029261
Diseasemyocardial infarction

ANKRD31 CUX2 DYNC2H1 PKD1L3 HAVCR1 VPS33B UNC5C PLCG2

3.69e-043501468EFO_0000612
DiseaseSchizophrenia

TNIK PSD INPP5A SREBF2 GRIA1 GRIA2 GRIA3 NLGN1 TENM4 UNC5C ERVK-8 KMT2A PICK1

4.62e-0488314613C0036341
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ANKRD31 TTC39B NHLRC2 REEP3 HAVCR1 TENM4 SPDEF

6.38e-042911467EFO_0008317, EFO_0020946
Diseasetriacylglycerol 58:6 measurement

TENM2 TOX3

6.68e-0481462EFO_0010440
Diseaseatypical hemolytic-uremic syndrome (is_implicated_in)

CD46 CFHR3

6.68e-0481462DOID:0080301 (is_implicated_in)
DiseaseAtypical hemolytic-uremic syndrome

CD46 CFHR3

8.56e-0491462cv:C2931788
DiseaseHemolytic-uremic syndrome

CD46 CFHR3

8.56e-0491462cv:C0019061
Diseasecoronary artery disease

ANKRD31 TTC39B CUX2 DYNC2H1 MTHFD1L PKD1L3 NEDD4 IGSF10 VPS33B UNC5C PAN2 PLCG2 ARHGAP20 STK24 TBCD

8.79e-04119414615EFO_0001645
Diseaseurate measurement, bone density

NAT1 MTHFD1L INPP5A SLC26A5 DGKD TENM2 THAP9 SFMBT2 GLP2R SLC30A9

1.06e-0361914610EFO_0003923, EFO_0004531
DiseaseAtypical Hemolytic Uremic Syndrome

CD46 CFHR3

1.07e-03101462C2931788
Diseasehigh grade glioma (is_marker_for)

ASPM PLAU AKT2

1.18e-03421463DOID:3070 (is_marker_for)
Diseaseage-related hearing impairment

EGLN3 SAMD9 MTHFD1L SLC26A5 GRIA1 NLGN1 PRR14L

1.19e-033241467EFO_0005782
Diseaseobesity

NAT1 SEC16B DGKD PFKFB3 ALPK1 ANO3

1.31e-032411466EFO_0001073
Diseasediffuse plaque measurement

TTC39B EGLN3 PSMF1 SAMD9 KLC4 TENM4 SHANK2 SPDEF SETD3 EIF2AK2 ANO3

1.42e-0375814611EFO_0010699
Diseasespecific language impairment, dyslexia

STK24 CCDC136

1.55e-03121462EFO_0005424, EFO_1001510
Diseaseend stage renal disease (biomarker_via_orthology)

NAT1 SREBF2 PLAU

1.64e-03471463DOID:783 (biomarker_via_orthology)
Diseaselifestyle measurement, depressive symptom measurement

DOCK1 EGLN3 GRIA1 NLGN1

1.87e-031051464EFO_0007006, EFO_0010724
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

ESRRB SLC26A5 MYO3A

2.08e-03511463cv:CN043650
DiseaseMalformations of Cortical Development

AKT3 TBCD

2.13e-03141462C1955869
Diseasetriacylglycerol 48:4 measurement

SFMBT2 TENM4

2.13e-03141462EFO_0010407
DiseaseCortical Dysplasia

AKT3 TBCD

2.13e-03141462C0431380
Diseaseglucose metabolism measurement, age-related hearing impairment

SAMD9 INPP5A CCNA1

2.20e-03521463EFO_0005782, EFO_0009367
DiseaseInfluenza

SAMD9 IFI44L EIF2AK2

2.20e-03521463C0021400
Diseasecancer (implicated_via_orthology)

AKT3 CUX2 ESRRB AXIN2 PIP5K1A AKT2

2.23e-032681466DOID:162 (implicated_via_orthology)
DiseaseMMR-related febrile seizures

IFI44L ANO3

2.45e-03151462EFO_0006519
Diseaseperiprosthetic osteolysis, disease progression measurement

INPP5A SFMBT2

2.45e-03151462EFO_0008336, EFO_0009761
DiseaseColorectal Carcinoma

DNAH3 MTHFD1L CD46 AXIN2 AKAP9 ABCB10 GUCY2C PAN2 ABCC2 CDH5

2.67e-0370214610C0009402
DiseaseChromosome Aberrations

NAT1 KMT2A

2.79e-03161462C0008625
DiseaseAutosome Abnormalities

NAT1 KMT2A

2.79e-03161462C0004403
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NCAPD2 ASPM

2.79e-03161462DOID:0070296 (is_implicated_in)
DiseaseAlzheimer disease

OARD1 ANKRD31 MTHFD1L TENM2 PLCG2 ARHGAP20 MAP4K4 STK24

2.94e-034851468MONDO_0004975
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

GRIA1 RFX7

3.15e-03171462DOID:0060307 (is_implicated_in)
Diseasepolycystic ovary syndrome

UNC5C TOX3 FSHR

3.30e-03601463EFO_0000660
Diseaseresponse to antipsychotic drug

TNIK DYNC2H1 TENM4

3.30e-03601463GO_0097332
Diseaseuric acid measurement

TNIK DNAH3 CUX2 DYNC2H1 INPP5A REEP3 TENM2 SLC20A2 EPB41L2

3.44e-036101469EFO_0004761
Diseaseurolithiasis

DGKD STK24 EPB41L2

3.79e-03631463MONDO_0024647
Diseaseneuroticism measurement, wellbeing measurement, depressive symptom measurement

SLC26A5 STK24

3.93e-03191462EFO_0007006, EFO_0007660, EFO_0007869
Diseaseblood arsenic measurement

CFHR3 HAVCR1

3.93e-03191462EFO_0021527
Diseasesusceptibility to vaginal yeast infection measurement

ANKRD31 EGLN3 GRHL3

4.14e-03651463EFO_0008412
Diseaset-tau:beta-amyloid 1-42 ratio measurement

SGIP1 DIP2A AKT2

4.32e-03661463EFO_0007708
DiseaseCCL4 measurement

TBC1D3 TBC1D3F

4.36e-03201462EFO_0004751
Diseaseprostate adenocarcinoma (is_implicated_in)

AKT3 AKT2

4.36e-03201462DOID:2526 (is_implicated_in)
Diseaseplatelet component distribution width

AKT3 NHLRC2 HAVCR1 SLC35B4 TNN TLN1 PLCG2 FYB1 VAV2 MYBPC1

4.45e-0375514610EFO_0007984
DiseaseGrand Mal Status Epilepticus

GRIA2 ABCC2 EIF2AK2

4.51e-03671463C0311335
DiseaseStatus Epilepticus, Subclinical

GRIA2 ABCC2 EIF2AK2

4.51e-03671463C0751522
DiseaseSimple Partial Status Epilepticus

GRIA2 ABCC2 EIF2AK2

4.51e-03671463C0751524
DiseaseNon-Convulsive Status Epilepticus

GRIA2 ABCC2 EIF2AK2

4.51e-03671463C0751523
DiseasePetit mal status

GRIA2 ABCC2 EIF2AK2

4.51e-03671463C0270823
DiseaseComplex Partial Status Epilepticus

GRIA2 ABCC2 EIF2AK2

4.51e-03671463C0393734
DiseaseSeizures

CUX2 GRIA2 ABCC2 PUM1 TBCD

4.67e-032181465C0036572
DiseaseStatus Epilepticus

GRIA2 ABCC2 EIF2AK2

4.70e-03681463C0038220
Diseasehepatitis B (is_marker_for)

PLAU MAP4K4

4.80e-03211462DOID:2043 (is_marker_for)
Diseaserisk-taking behaviour

AKT3 SGIP1 GRIA1 NLGN1 REV3L PKD1L3 TENM2 NEO1 TENM4 STK24

4.83e-0376414610EFO_0008579
Diseasecongenital heart disease (implicated_via_orthology)

AXIN2 KMT2A MYBPC1

4.90e-03691463DOID:1682 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KAARVIIEKYYTRLG

RPS17

11

P08708
LAQYIFTLKRKTGRK

NT5C3A

31

Q9H0P0
EKATGRYYAMKILRK

AKT2

171

P31751
YLERIGYKKSRNKLD

NAT1

6

P18440
LEDSKYRKIYSFTLK

NAT1

181

P18440
VTLKRIYGKYLRAES

AKAP9

3696

Q99996
VTGKTRTKEKYRVVY

CDX4

166

O14627
YLKKGTFKYRISVGA

MACROH2A2

31

Q9P0M6
GLTYYLVRFKGSKKD

FERMT1

566

Q9BQL6
IYGRYLRKLTKVTQD

ABCB10

331

Q9NRK6
KTLRVAKAIYKRYIE

AXIN2

126

Q9Y2T1
SSGFRLVKKKLYSLI

DDIT4L

171

Q96D03
EKKAYLKRRYGLIST

CUX2

1126

O14529
YGKSKAKVRLSVLER

MTHFD1L

391

Q6UB35
LKTIYRKAVKYDLGS

CC2D2B

261

Q6DHV5
KYLLKGEYVGKVFRV

CDH5

81

P33151
GSRLGKYYVKERSKA

EGLN3

106

Q9H6Z9
LYKRRKESILTIQKY

ASPM

1506

Q8IZT6
KVILVREKASGKYYA

AKT3

161

Q9Y243
IVYLGDYLTVKKKGR

ALPK1

1031

Q96QP1
LFKDGKKRIDYILVY

ANO3

156

Q9BYT9
KKRIDYILVYRKTNI

ANO3

161

Q9BYT9
SLKKIYDREQTRYKA

IQGAP1

91

P46940
ELLSTKFKYRYEGKI

RAG1

921

P15918
RKIAESGRGKRYSYK

ADAMTS19

306

Q8TE59
KPRRVASYKKGTLEY

GUCY2C

1046

P25092
LRKYTYGKHILAKLE

PUM2

1031

Q8TB72
VLKKYDYDSSSVRKR

NIBAN2

476

Q96TA1
IYFGRSKKRLSTLKF

MORC1

81

Q86VD1
SKVTYLGKELLRYVS

ANKRD31

1766

Q8N7Z5
KLRNFYRKLETKGYG

HECW2

1196

Q9P2P5
LAVLYGKRGKYKEAE

KLC4

301

Q9NSK0
LKRDGRYIYYLITKK

OARD1

71

Q9Y530
YRKVTIKYSKLGLED

PAN2

491

Q504Q3
TISGKKDKLRVYYLS

MAP4K4

981

O95819
YRYLQRRKKKGTYLT

CD46

366

P15529
KSRVKGYLRLKMTYL

NEDD4

556

P46934
LVRFTEKRYKSIVKY

FDPS

251

P14324
RYRIYSVKDGKNGKS

IFI44L

241

Q53G44
LKISYKRSNFYIKVR

EPB41L2

446

O43491
VARVRKSKGKYAYLL

GRIA2

711

P42262
VRIKYKLSIVGDGKY

GRIA3

466

P42263
KYRKVAGKEIYSDTL

INPP5A

126

Q14642
RGKTYISKKLTRYLN

PFKFB3

46

Q16875
RKKFKYDGEIRVLYS

FYB1

696

O15117
LYIYKDREVTKKLVR

HAO1

131

Q9UJM8
SAYLYARFNKIKKLT

OGN

121

P20774
YLDYRKKAIKDLGIS

GLT8D2

206

Q9H1C3
YKKALTLSNLARKEY

ABCC2

401

Q92887
QRTVKALYDYKAKRS

PLCG2

771

P16885
ILAFAALYYKKDKRR

NLGN1

731

Q8N2Q7
IKYDLKGSTYKRRAS

PIP5K1A

256

Q99755
TSIALKYYKDRGQIR

NHLRC2

191

Q8NBF2
LRKYTYGKHILAKLE

PUM1

1151

Q14671
KYASYLSFIKILLKR

ERVK-10

11

P87889
KYASYLSFIKILLKR

ERVK-19

11

Q9YNA8
KYASYLSFIKILLKR

ERVK-21

11

P62683
KYASYLSFIKILLKR

ERVK-24

11

P63145
KYASYLSFIKILLKR

ERVK-5

11

Q9HDB9
KYASYLSFIKILLKR

ERVK-6

11

Q7LDI9
KYASYLSFIKILLKR

ERVK-7

11

P63130
KYASYLSFIKILLKR

ERVK-8

11

P62685
KYASYLSFIKILLKR

ERVK-9

11

P63126
KYASYLSFIKILLKR

HERVK_113

11

P62684
YDSTRGRLATYVLKK

DYNC2H1

2231

Q8NCM8
KLKGRSDRKYYAKTG

CFHR3

281

Q02985
KVRKLQKDTFYGLRS

IGSF10

116

Q6WRI0
FRDYKYRLAKSTLVL

GLP2R

376

O95838
YKVYKKCKRGETSLL

GRHL3

556

Q8TE85
YRGYTLRKKSKKGIF

DOCK1

46

Q14185
YRSELKAIRLGQKSY

DNAH17

3456

Q9UFH2
SVKKLSLDYYNKLRR

DNAH3

2631

Q8TD57
HRIDGKTYVIKRVKY

EIF2AK2

286

P19525
IREKYKASKYLCVSL

CCNA1

441

P78396
KLRGRTLYYAKTAKS

DGKD

76

Q16760
YFSSAKYAKEGLIRK

KMT2A

631

Q03164
QAGKILLYYKARTKD

HGSNAT

516

Q68CP4
EYVAIKTKKRILLYT

ERCC3

521

P19447
KGYEKKRAKLLARYI

DIP2A

36

Q14689
YRAILQLVRRYKKLK

ESRRB

321

O95718
YGLENLKKLRARSTY

FSHR

236

P23945
RVRKSKGKYAYLLES

GRIA1

706

P42261
KKVYVGGLESRVLKY

CREB3

171

O43889
RGKLSLSDKFRKEYY

SAMD15

446

Q9P1V8
LVGDTVSYSKKRLRY

SLC20A2

416

Q08357
RLYKSSKIGKRVALE

PRIMPOL

291

Q96LW4
VLRYEYKDGSRKLLV

PSMF1

66

Q92530
YKRLRYKRLLDGFSS

PRR14L

1651

Q5THK1
LRYGFTKEILHKYKL

PPEF1

241

O14829
KLTYLRGIYSKKQHK

ARHGAP20

856

Q9P2F6
RSYLQYRGKKFKDRK

RGSL1

986

A5PLK6
KKEDYIVYLGRSRLN

PLAU

231

P00749
ILKKRYSIFKYTSIA

SLC35B4

111

Q969S0
RYSTYAALLRVKLKA

PSD

951

A5PKW4
FSSGELIYKKKTRLL

TC2N

396

Q8N9U0
KKTSYLTELIDRYKR

STK24

291

Q9Y6E0
KTRRKVAGYFKKYVD

SAMD9

1291

Q5K651
IYSLIDKKKQFRSRG

TAF1D

116

Q9H5J8
LKYLFGVKTKRYSGI

SLC26A5

226

P58743
YRKDTRYKLLGDLSR

HAVCR1

71

Q96D42
ITGYKIRYRKASRKS

NEO1

666

Q92859
RISSKGDKCLLKYYF

PKD1L3

121

Q7Z443
VRSLTYFSARKGKRK

MRPL35

91

Q9NZE8
VKGQVTTKYYRLLSK

SIM2

286

Q14190
RVKIKLGVSKSDRLY

SETD3

336

Q86TU7
RQVFYKYGKLSKLSE

TENM2

2016

Q9NT68
EKYKSSRKLIDRAYK

TBC1D3L

86

B9A6J9
TTKGRKEVRYGSLKY

REEP3

231

Q6NUK4
GKIYFRSYKLLLKKS

RPF2

191

Q9H7B2
KYASYLSFIKILLKR

ERVK-9

11

P63128
KGFFKRTIRKDLTYS

RXRB

226

P28702
LEFRYKKRVYKQASL

SHANK2

136

Q9UPX8
LYYKASQRKLDGLAK

CCDC136

1021

Q96JN2
VKGRIYQLLAKASYK

NCAPD2

516

Q15021
ELEAKQLRRLYKYTK

C17orf64

121

Q86WR6
RYYITRAKLVSKIAK

PSME3

181

P61289
EKYKSSRKLIDRAYK

TBC1D3B

86

A6NDS4
EKYKSSRKLIDRAYK

TBC1D3H

86

P0C7X1
GRLKRKKLLKEYYST

UHRF1BP1L

761

A0JNW5
VTISGKKNKLRVYYL

TNIK

1101

Q9UKE5
IKGGLKIRTSYQIYK

TTC39B

261

Q5VTQ0
KRTLYSKKYGVDLIR

WDR82

56

Q6UXN9
KKKYERGSATNYITR

PES1

6

O00541
RALRKVFLSIKGIYY

PES1

176

O00541
GLYGNKYTLRAKRKV

REV3L

911

O60673
ASSKERYKLTVGKYR

TNN

1181

Q9UQP3
LCSSKVYDYVRKILK

THAP9

221

Q9H5L6
EKYKSSRKLIDRAYK

TBC1D3F

86

A6NER0
IIFVYYLRKGKKINS

SPANXN3

51

Q5MJ09
RFSLIKKRFAAGKYL

SGIP1

811

Q9BQI5
GLSRVYSKLYKEAEK

SYCP1

101

Q15431
VRYVKLARSLKTYGV

TLN1

296

Q9Y490
SRSIRQYYKKGIIRK

SPDEF

306

O95238
RKDRRIVSKKYKIYF

SIDT1

431

Q9NXL6
YVKKGSRIYLEGKID

SSBP1

101

Q04837
LKAELLKRYTKEYTE

STAMBP

106

O95630
KTIEESLIYRKKYIL

SYCP2

731

Q9BX26
SLIYRKKYILSKDVN

SYCP2

736

Q9BX26
KSGVLRKAIDYIKYL

SREBF2

366

Q12772
QGLRTLYKRLKEYAK

FSBP

66

O95073
QEETLKAKYRGKTYR

SFMBT2

596

Q5VUG0
KAKYRGKTYRAVVKI

SFMBT2

601

Q5VUG0
RYLFALLVGTKRKYV

USP25

226

Q9UHP3
TGRRVIYKYGKLSKL

TENM4

2006

Q6N022
AARRRKKKSYYAKLR

IK

71

Q13123
TRGKSKYCYSGLRKK

RFX7

71

Q2KHR2
AKKEYLKALAAYRAS

TOX3

311

O15405
LKEIRKTVSGTALYY

TTC21A

101

Q8NDW8
IVEKFTRLLYYGRKK

SEC16B

441

Q96JE7
LYRKSKALSDLGRYK

ZC3H7A

126

Q8IWR0
YAATKTKYRKRLDAA

ZBED5

651

Q49AG3
GSYAKVKSAYSERLK

TSSK1B

21

Q9BXA7
LYRIFSKYGKVVKVT

ZCRB1

26

Q8TBF4
RVKAVLKKREYGSKY

SLC30A9

111

Q6PML9
LYIITKVRGYKTFLR

TBCD

106

Q9BTW9
LLSVVFLATYYKRKR

TMEM154

91

Q6P9G4
EKYKSSRKLIDRAYK

TBC1D3D

86

A0A087WVF3
IITGLAYFLLSKRKK

TMEM72

121

A0PK05
VCKRKGYSYELKEII

VAV2

436

P52735
EKEILFYRKTIGYKV

SMARCA5

786

O60264
EKYKSSRKLIDRAYK

TBC1D3G

86

Q6DHY5
EKYKSSRKLIDRAYK

TBC1D3

86

Q8IZP1
TRLTIKKYLDVKFEY

PICK1

246

Q9NRD5
LGSSKTDLFYERKKY

PHF5A

91

Q7RTV0
GSYAKVKSAYSERLK

TSSK2

21

Q96PF2
GTTKSRKAYVRIAYL

UNC5C

151

O95185
EKYKSSRKLIDRAYK

TBC1D3K

86

A0A087X1G2
ADKLAGRTRKYKVIF

VPS33B

101

Q9H267
VLTLKKFKGDLAYRR

ZHX1-C8orf76

21

Q96EF9
EKYKSSRKLIDRAYK

TBC1D3I

86

A0A087WXS9
EKYKSSRKLIDRAYK

TBC1D3C

86

Q6IPX1
RLFITIYKDALKGKY

ZFYVE16

1116

Q7Z3T8
LKNDSLRKRYDGLKY

TSN

186

Q15631
KRKELLKYLTAASYL

ZBTB6

96

Q15916
RKYDKEKVLLQLRYT

MYO3A

961

Q8NEV4
ILGYFIERKKKQSSR

MYBPC1

651

Q00872