Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	ATR ATM	6.42e-05	3	93	2	GO:0035979
GeneOntologyMolecularFunction	histone H2AX kinase activity	ATR ATM	2.13e-04	5	93	2	GO:0141003
GeneOntologyMolecularFunction	dolichyl-phosphate-mannose-protein mannosyltransferase activity	TMTC4 TMTC2	5.90e-04	8	93	2	GO:0004169
GeneOntologyBiologicalProcess	telomerase catalytic core complex assembly	ATR ATM	1.97e-05	2	92	2	GO:1904868
GeneOntologyBiologicalProcess	positive regulation of telomerase catalytic core complex assembly	ATR ATM	1.97e-05	2	92	2	GO:1904884
GeneOntologyBiologicalProcess	regulation of telomerase catalytic core complex assembly	ATR ATM	1.97e-05	2	92	2	GO:1904882
GeneOntologyBiologicalProcess	establishment of RNA localization to telomere	ATR ATM	5.89e-05	3	92	2	GO:0097694
GeneOntologyBiologicalProcess	establishment of protein-containing complex localization to telomere	ATR ATM	5.89e-05	3	92	2	GO:0097695
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	MRTFB PPP2R5D ERCC6 ZBTB7C ZNF827 MTF1 PPRC1 SREBF1 IRF3 CAMTA2 ATM TBR1 BCL9 MEIS2 MAF MEOX1 NPAT	1.24e-04	1390	92	17	GO:0045944
GeneOntologyBiologicalProcess	neuron projection development	ERBB2 MRTFB PPP2R5D NRXN3 ERCC6 USP9X DAB1 ADGRB3 PRKCI PRKG1 RERE TBR1 ADNP PIP5K1C CDH4 OTOG	1.65e-04	1285	92	16	GO:0031175
HumanPheno	Long philtrum	PPP2R5D ERCC6 RTL1 USP9X ANKRD11 FGD1 RERE ADNP SPEN MEIS2 MAF	1.14e-05	429	29	11	HP:0000343
HumanPheno	Upper-limb joint contracture	PPP2R5D ERCC6 ATR DSP RTL1 FGD1 RERE TBR1 SPEN PLEKHG5	1.71e-05	362	29	10	HP:0100360
HumanPheno	Joint contractures	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 PIP5K1C SPEN	2.14e-05	292	29	9	HP:0001372
HumanPheno	Joint contracture of the hand	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN PLEKHG5	2.38e-05	296	29	9	HP:0009473
HumanPheno	Flexion contracture of finger	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	3.92e-05	240	29	8	HP:0005651
HumanPheno	Camptodactyly (hands)	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	3.92e-05	240	29	8	HP:0010563
HumanPheno	Joint contractures involving the joints of the feet	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	3.92e-05	240	29	8	HP:0100492
HumanPheno	Camptodactyly of finger	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	3.92e-05	240	29	8	HP:0100490
HumanPheno	Interphalangeal joint contracture of finger	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	3.92e-05	240	29	8	HP:0001220
HumanPheno	Camptodactyly of toe	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	3.92e-05	240	29	8	HP:0001836
HumanPheno	Flexion contracture of toe	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	3.92e-05	240	29	8	HP:0005830
HumanPheno	Toe joint contracture	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	4.04e-05	241	29	8	HP:0034675
HumanPheno	High anterior hairline	FGD1 RERE ADNP SPEN MEIS2	5.81e-05	76	29	5	HP:0009890
HumanPheno	Flexion contracture of finger	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	6.40e-05	257	29	8	HP:0012785
HumanPheno	Finger joint contracture	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	6.76e-05	259	29	8	HP:0034681
HumanPheno	Abnormal phalangeal joint morphology of the hand	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	7.34e-05	262	29	8	HP:0006261
HumanPheno	Camptodactyly	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN MAF	8.22e-05	346	29	9	HP:0012385
HumanPheno	Flexion contracture of digit	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN MAF	1.17e-04	362	29	9	HP:0030044
HumanPheno	Abnormal toe morphology	PPP2R5D ERCC6 ATR DSP RTL1 USP9X FGD1 PRKG1 RERE TBR1 ADNP SPEN PLEKHG5 MEIS2	1.33e-04	893	29	14	HP:0001780
HumanPheno	Abnormal cardiac ventricle morphology	PPP2R5D DSP RTL1 SREBF1 ANKRD11 TMPO ATM PRKG1 RERE SPEN MEIS2 ZNF687 MEOX1	1.44e-04	780	29	13	HP:0001713
HumanPheno	Limb joint contracture	PPP2R5D ERCC6 ATR DSP RTL1 FGD1 RERE TBR1 SPEN PLEKHG5	1.59e-04	469	29	10	HP:0003121
HumanPheno	Abnormal size of the palpebral fissures	ERCC6 ATR RTL1 USP9X ANKRD11 RERE ADNP SPEN	1.82e-04	298	29	8	HP:0200007
HumanPheno	Orofacial cleft	PPP2R5D ATR DSP RTL1 USP9X ANKRD11 FGD1 RERE TBR1 MEIS2 MAF MEOX1	2.09e-04	694	29	12	HP:0000202
HumanPheno	Craniofacial cleft	PPP2R5D ATR DSP RTL1 USP9X ANKRD11 FGD1 RERE TBR1 MEIS2 MAF MEOX1	2.09e-04	694	29	12	HP:5201015
HumanPheno	Flexion contracture	PPP2R5D ERCC6 ATR DSP RTL1 FGD1 ATM RERE TBR1 PIP5K1C SPEN PLEKHG5 MAF	2.33e-04	817	29	13	HP:0001371
HumanPheno	Abnormal palate morphology	PPP2R5D FRMPD4 ATR DSP RTL1 USP9X ANKRD11 FGD1 PRKG1 RERE TBR1 ADNP SPEN MEIS2 MAF MEOX1	2.35e-04	1202	29	16	HP:0000174
HumanPheno	Abnormality of upper limb joint	PPP2R5D ERCC6 ATR DSP RTL1 FGD1 RERE TBR1 SPEN PLEKHG5 MAF MEOX1	2.44e-04	705	29	12	HP:0009810
HumanPheno	Downslanted palpebral fissures	PPP2R5D ATR USP9X ANKRD11 FGD1 RERE TBR1 ADNP SPEN MAF	2.58e-04	497	29	10	HP:0000494
HumanPheno	Abnormal joint physiology	PPP2R5D ERCC6 ATR DSP RTL1 USP9X ANKRD11 FGD1 ATM RERE TBR1 ADNP PIP5K1C SPEN PLEKHG5 MAF MEOX1	2.73e-04	1358	29	17	HP:0034430
HumanPheno	Abnormality of joint mobility	PPP2R5D ERCC6 ATR DSP RTL1 USP9X ANKRD11 FGD1 ATM RERE TBR1 ADNP PIP5K1C SPEN PLEKHG5 MAF MEOX1	2.73e-04	1358	29	17	HP:0011729
HumanPheno	Abnormality of the chin	ERCC6 RTL1 ANKRD11 FGD1 RERE ADNP SPEN MEIS2 MAF	2.98e-04	409	29	9	HP:0000306
HumanPheno	3-4 finger osseus syndactyly	DSP RERE	3.10e-04	5	29	2	HP:0006097
HumanPheno	Joint contracture	PPP2R5D ERCC6 ATR DSP RTL1 FGD1 ATM RERE TBR1 PIP5K1C SPEN PLEKHG5 MAF	3.21e-04	843	29	13	HP:0034392
HumanPheno	Abnormality of the philtrum	PPP2R5D ERCC6 RTL1 USP9X ANKRD11 FGD1 RERE TBR1 ADNP SPEN MEIS2 MAF	3.23e-04	726	29	12	HP:0000288
HumanPheno	Congenital abnormal hair pattern	FRMPD4 ANKRD11 FGD1 RERE ADNP SPEN MEIS2 MEOX1	3.45e-04	327	29	8	HP:0011361
HumanPheno	Abnormal finger morphology	ERBB2 PPP2R5D ERCC6 ATR DSP RTL1 USP9X SREBF1 ANKRD11 FGD1 PRKG1 RERE TBR1 ADNP SPEN MEIS2 MAF	3.53e-04	1385	29	17	HP:0001167
HumanPheno	Abnormal finger phalanx morphology	PPP2R5D ERCC6 ATR DSP RTL1 USP9X FGD1 RERE TBR1 ADNP SPEN MEIS2	3.78e-04	738	29	12	HP:0005918
HumanPheno	Abnormal stomach morphology	ERBB2 PPP2R5D ERCC6 CD19 DSP RTL1 USP9X ATM RERE ADNP SPEN MEIS2	3.97e-04	742	29	12	HP:0002577
HumanPheno	Foot joint contracture	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	3.98e-04	334	29	8	HP:0008366
HumanPheno	Brachycephaly	CD19 USP9X ANKRD11 RERE ADNP SPEN MAF	4.17e-04	253	29	7	HP:0000248
HumanPheno	Scoliosis	PPP2R5D ERCC6 ATR RTL1 USP9X ANKRD11 FGD1 PRKG1 RERE ADNP SPEN PLEKHG5 MEIS2 MAF MEOX1	4.18e-04	1122	29	15	HP:0002650
HumanPheno	Abnormality of the scalp hair	ATR ANKRD11 FGD1 RERE ADNP SPEN MEIS2 MAF MEOX1	4.56e-04	433	29	9	HP:0100037
HumanPheno	Osseous finger syndactyly	DSP RERE	4.63e-04	6	29	2	HP:0010492
HumanPheno	Abnormal tendon morphology	PPP2R5D ERCC6 ATR DSP RTL1 FGD1 ATM RERE TBR1 PIP5K1C SPEN PLEKHG5 MAF	4.69e-04	875	29	13	HP:0100261
HumanPheno	Cleft palate	PPP2R5D ATR DSP RTL1 USP9X ANKRD11 FGD1 TBR1 MEIS2 MAF MEOX1	4.79e-04	643	29	11	HP:0000175
HumanPheno	Abnormality of the palpebral fissures	PPP2R5D ERCC6 ATR RTL1 USP9X ANKRD11 FGD1 RERE TBR1 ADNP SPEN MEIS2 MAF	4.97e-04	880	29	13	HP:0008050
HumanPheno	Smooth philtrum	USP9X ANKRD11 RERE ADNP MEIS2 MAF	5.00e-04	185	29	6	HP:0000319
HumanPheno	Abnormal hard palate morphology	PPP2R5D ATR DSP RTL1 USP9X ANKRD11 FGD1 TBR1 MEIS2 MAF MEOX1	5.05e-04	647	29	11	HP:0100737
HumanPheno	Abnormal breast morphology	PPP2R5D ERCC6 ATR RTL1 USP9X ATM RERE ADNP MAF	5.23e-04	441	29	9	HP:0031093
HumanPheno	Abnormality of the breast	PPP2R5D ERCC6 ATR RTL1 USP9X ATM RERE ADNP MAF	5.78e-04	447	29	9	HP:0000769
HumanPheno	Abnormal scalp morphology	ATR ANKRD11 FGD1 RERE ADNP SPEN MEIS2 MAF MEOX1	6.07e-04	450	29	9	HP:0001965
HumanPheno	Abnormal pinna morphology	PPP2R5D ERCC6 FRMPD4 ATR DSP RTL1 USP9X ANKRD11 FGD1 RERE TBR1 ADNP SPEN MEIS2 MAF MEOX1	6.09e-04	1299	29	16	HP:0000377
HumanPheno	Finger clinodactyly	ATR DSP RTL1 ANKRD11 FGD1 RERE ADNP SPEN MAF	6.28e-04	452	29	9	HP:0040019
HumanPheno	Abnormal hair pattern	ERCC6 FRMPD4 RTL1 USP9X ANKRD11 FGD1 RERE ADNP SPEN MEIS2 MEOX1	7.40e-04	676	29	11	HP:0010720
HumanPheno	Posteriorly rotated ears	RTL1 USP9X ANKRD11 FGD1 RERE TBR1 ADNP SPEN MAF	8.36e-04	470	29	9	HP:0000358
HumanPheno	Congenital muscular torticollis	PPP2R5D MEOX1	8.58e-04	8	29	2	HP:0005988
HumanPheno	Abnormality of the outer ear	PPP2R5D ERCC6 FRMPD4 ATR DSP RTL1 USP9X ANKRD11 FGD1 RERE TBR1 ADNP SPEN MEIS2 MAF MEOX1	8.60e-04	1337	29	16	HP:0000356
HumanPheno	Abnormality of hair texture	ERCC6 ATR DSP USP9X SREBF1 ADNP MAF	9.50e-04	290	29	7	HP:0010719
HumanPheno	Pointed chin	ANKRD11 FGD1 RERE SPEN MEIS2	9.54e-04	138	29	5	HP:0000307
HumanPheno	Abnormality of the hairline	ANKRD11 FGD1 RERE ADNP SPEN MEIS2 MEOX1	1.03e-03	294	29	7	HP:0009553
HumanPheno	Abnormal curvature of the vertebral column	PPP2R5D ERCC6 ATR RTL1 USP9X ANKRD11 FGD1 PRKG1 RERE ADNP SPEN PLEKHG5 MEIS2 MAF MEOX1	1.07e-03	1219	29	15	HP:0010674
HumanPheno	Ivory epiphyses	ERCC6 ATR	1.10e-03	9	29	2	HP:0010583
HumanPheno	Single transverse palmar crease	ATR RTL1 ANKRD11 FGD1 RERE ADNP	1.11e-03	215	29	6	HP:0000954
HumanPheno	Abnormality of the frontal hairline	ANKRD11 FGD1 RERE ADNP SPEN MEIS2	1.11e-03	215	29	6	HP:0000599
HumanPheno	Broad phalanx	RTL1 USP9X RERE ADNP MEIS2	1.31e-03	148	29	5	HP:0006009
HumanPheno	Broad phalanges of the hand	RTL1 USP9X RERE ADNP MEIS2	1.31e-03	148	29	5	HP:0009768
HumanPheno	Facial asymmetry	PPP2R5D ATR USP9X MAF MEOX1	1.35e-03	149	29	5	HP:0000324
HumanPheno	Lower-limb joint contracture	PPP2R5D ERCC6 DSP RTL1 FGD1 RERE TBR1 SPEN	1.39e-03	403	29	8	HP:0005750
HumanPheno	Abnormal upper lip morphology	PPP2R5D ERCC6 RTL1 USP9X ANKRD11 FGD1 RERE TBR1 ADNP SPEN MEIS2 MAF MEOX1	1.44e-03	980	29	13	HP:0000177
HumanPheno	Wide nasal bridge	ERCC6 FRMPD4 RTL1 USP9X FGD1 RERE ADNP SPEN MAF	1.47e-03	508	29	9	HP:0000431
HumanPheno	Abnormal 5th finger morphology	ATR DSP ANKRD11 FGD1 RERE ADNP SPEN MEIS2 MAF	1.49e-03	509	29	9	HP:0004207
HumanPheno	Abnormal thumb morphology	ERBB2 RTL1 USP9X SREBF1 ANKRD11 RERE ADNP MEIS2	1.51e-03	408	29	8	HP:0001172
HumanPheno	Short foot	RTL1 USP9X FGD1 RERE SPEN	1.52e-03	153	29	5	HP:0001773
HumanPheno	Short feet	RTL1 USP9X FGD1 RERE SPEN	1.52e-03	153	29	5	HP:0001766
HumanPheno	Small feet	RTL1 USP9X FGD1 RERE SPEN	1.52e-03	153	29	5	HP:0001764
HumanPheno	Broad thumb	USP9X RERE ADNP MEIS2	1.54e-03	90	29	4	HP:0011304
HumanPheno	Broad finger	RTL1 USP9X RERE ADNP MEIS2	1.56e-03	154	29	5	HP:0001500
HumanPheno	Slanting of the palpebral fissure	PPP2R5D ATR USP9X ANKRD11 FGD1 RERE TBR1 ADNP SPEN MEIS2 MAF	1.58e-03	739	29	11	HP:0200006
HumanPheno	Abnormal nail morphology	PPP2R5D ATR DSP RTL1 SREBF1 RERE ADNP SPEN MAF	1.64e-03	516	29	9	HP:0001597
HumanPheno	Abnormal vertebral segmentation and fusion	FGD1 MEOX1	1.67e-03	11	29	2	HP:0005640
HumanPheno	Neuroepithelial neoplasm	ERBB2 ATM RERE SPEN	1.67e-03	92	29	4	HP:0030063
HumanPheno	Broad long bones	RTL1 USP9X RERE ADNP MEIS2	1.70e-03	157	29	5	HP:0005622
HumanPheno	Abnormal hair morphology	ERCC6 FRMPD4 ATR DSP RTL1 USP9X SREBF1 ANKRD11 FGD1 ATM RERE ADNP SPEN MEIS2 MAF MEOX1	1.80e-03	1424	29	16	HP:0001595
HumanPheno	Neuroectodermal neoplasm	ERBB2 ATM RERE SPEN	1.81e-03	94	29	4	HP:0030061
HumanPheno	Nervous tissue neoplasm	ERBB2 ATM RERE SPEN	1.81e-03	94	29	4	HP:0030060
HumanPheno	Clinodactyly of the 5th finger	ATR DSP ANKRD11 FGD1 RERE ADNP SPEN MAF	1.82e-03	420	29	8	HP:0004209
HumanPheno	Clinodactyly of hands	ATR DSP ANKRD11 FGD1 RERE ADNP SPEN MAF	1.85e-03	421	29	8	HP:0001157
HumanPheno	Deviation of the 5th finger	ATR DSP ANKRD11 FGD1 RERE ADNP SPEN MAF	1.85e-03	421	29	8	HP:0009179
HumanPheno	Telangiectasia	ERCC6 ATR ATM RERE SPEN	1.90e-03	161	29	5	HP:0001009
HumanPheno	Sandal gap	ATR DSP ADNP MEIS2	1.96e-03	96	29	4	HP:0001852
Domain	MAGEA3/MAGEA6	MAGEA3 MAGEA6	2.25e-05	2	89	2	IPR030097
Domain	MAGE_N	MAGEA3 MAGEA6 MAGEA12	1.12e-04	20	89	3	SM01392
Domain	DUF1736	TMTC4 TMTC2	1.34e-04	4	89	2	IPR013618
Domain	DUF1736	TMTC4 TMTC2	1.34e-04	4	89	2	PF08409
Domain	MAGE_N	MAGEA3 MAGEA6 MAGEA12	1.51e-04	22	89	3	PF12440
Domain	MAGE_N	MAGEA3 MAGEA6 MAGEA12	1.51e-04	22	89	3	IPR021072
Domain	DDE_Tnp_1_7	ERCC6 PGBD2	2.22e-04	5	89	2	PF13843
Domain	FATC	ATR ATM	2.22e-04	5	89	2	PF02260
Domain	PGBD	ERCC6 PGBD2	2.22e-04	5	89	2	IPR029526
Domain	FAT	ATR ATM	3.33e-04	6	89	2	PS51189
Domain	FATC	ATR ATM	3.33e-04	6	89	2	PS51190
Domain	FAT	ATR ATM	3.33e-04	6	89	2	PF02259
Domain	PIK-rel_kinase_FAT	ATR ATM	3.33e-04	6	89	2	IPR003151
Domain	FATC_dom	ATR ATM	3.33e-04	6	89	2	IPR003152
Domain	PIK_FAT	ATR ATM	3.33e-04	6	89	2	IPR014009
Domain	FATC	ATR ATM	3.33e-04	6	89	2	SM01343
Domain	MAGE	MAGEA3 MAGEA6 MAGEA12	5.62e-04	34	89	3	SM01373
Domain	MAGE	MAGEA3 MAGEA6 MAGEA12	6.67e-04	36	89	3	PS50838
Domain	MAGE	MAGEA3 MAGEA6 MAGEA12	6.67e-04	36	89	3	PF01454
Domain	MHD_dom	MAGEA3 MAGEA6 MAGEA12	6.67e-04	36	89	3	IPR002190
Domain	PI3/4_kinase_CS	ATR ATM	2.26e-03	15	89	2	IPR018936
Domain	-	ATR ATM	2.58e-03	16	89	2	1.10.1070.11
Domain	PI3Kc	ATR ATM	2.58e-03	16	89	2	SM00146
Domain	PI3/4_kinase_cat_dom	ATR ATM	3.27e-03	18	89	2	IPR000403
Domain	PI3_PI4_kinase	ATR ATM	3.27e-03	18	89	2	PF00454
Domain	PI3_4_KINASE_3	ATR ATM	3.27e-03	18	89	2	PS50290
Domain	PI3_4_KINASE_1	ATR ATM	3.27e-03	18	89	2	PS00915
Domain	PI3_4_KINASE_2	ATR ATM	3.27e-03	18	89	2	PS00916
Domain	PH_dom-like	AGAP5 FRMPD4 APPL2 DAB1 FGD1 PLEKHG5 SNTB2	4.23e-03	426	89	7	IPR011993
Domain	tRNA-bd_arm	DSP PRKG1	5.79e-03	24	89	2	IPR010978
Domain	PID	APPL2 DAB1	7.83e-03	28	89	2	PF00640
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CDCA2 ZHX3 RAD51AP1 WIZ DSP ATAD5 AHNAK GTSE1 MARF1 ANKRD11 TMPO ICE1 ADNP SPEN HDGFL2 NPAT	5.64e-09	954	94	16	36373674
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LRIG3 AGAP5 ERBB2 NRXN3 NUAK1 ADGRB3 TMEM131L AKAP11 ICE1 ADNP PLEKHG5 ZNF687	2.09e-08	529	94	12	14621295
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SCAF1 ERBB2 WIZ NUAK1 ZNF827 PPRC1 AHNAK GTSE1 SREBF1 ANKRD11 ICE1 BCL9 PIP5K1C SPEN PLEKHG5 ZNF687	4.35e-08	1105	94	16	35748872
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SCAF1 ZHX3 SEC16B ATR DSP GTSE1 TMPO ATM RERE BCL9 PNISR SPEN ZNF687	1.71e-07	774	94	13	15302935
Pubmed	Cloning and analysis of MAGE-1-related genes.	MAGEA3 MAGEA6 MAGEA12	1.90e-07	5	94	3	8037761
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EHBP1 MRTFB WIZ DSP AHNAK ICE1 RERE ADNP ZNF687 NPAT	2.08e-07	418	94	10	34709266
Pubmed	Human transcription factor protein interaction networks.	CDCA2 ZHX3 CNOT11 WIZ ATAD5 USP9X MARF1 IRF3 RERE TBR1 BCL9 ADNP SPEN PACSIN2 SNTB2 ZNF687 NPAT	2.60e-07	1429	94	17	35140242
Pubmed	Expression of melanoma-associated antigens in oral squamous cell carcinoma.	MAGEA3 MAGEA6 MAGEA12	6.64e-07	7	94	3	18197853
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CDCA2 ZHX3 RAD51AP1 ERCC6 WIZ ATAD5 TMPO ADNP SPEN HDGFL2 NPAT	7.93e-07	608	94	11	36089195
Pubmed	MAGE cancer-testis antigens protect the mammalian germline under environmental stress.	MAGEA3 MAGEA6 MAGEA12	1.06e-06	8	94	3	31149633
Pubmed	The Magea gene cluster regulates male germ cell apoptosis without affecting the fertility in mice.	MAGEA3 MAGEA6 MAGEA12	1.06e-06	8	94	3	27226137
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CDCA2 SCAF1 WIZ ATR DSP ATAD5 AHNAK SREBF1 ANKRD11 TMPO ADNP PNISR SPEN HDGFL2 ZNF687	1.97e-06	1294	94	15	30804502
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SCAF1 CNOT11 MRTFB ERCC6 WIZ APPL2 BMP2K ATAD5 ANKRD11 OS9 ICE1 PNISR SPEN HDGFL2 SNTB2 ZNF687	2.47e-06	1497	94	16	31527615
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 MRTFB GTSE1 ATM BCL9 ADNP PIP5K1C SPEN C2orf68	2.61e-06	430	94	9	35044719
Pubmed	Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53.	ERCC6 ATR ATM	4.13e-06	12	94	3	21522133
Pubmed	CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.	IGFBP4 CIART PRKG1 PNISR HDGFL2	5.88e-06	94	94	5	37468549
Pubmed	Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip.	SREBF1 TMPO ATM CDH4 MEIS2	6.19e-06	95	94	5	21440680
Pubmed	The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28.	MAGEA3 MAGEA6 MAGEA12	6.81e-06	14	94	3	8575766
Pubmed	Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks.	ATR ATM	7.23e-06	2	94	2	19285939
Pubmed	Expression variations of DNA damage response genes ATM and ATR in blood cancer patients.	ATR ATM	7.23e-06	2	94	2	37338595
Pubmed	DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes.	ATR ATM	7.23e-06	2	94	2	28851706
Pubmed	Quantitative phosphoproteomics reveals mitotic function of the ATR activator ETAA1.	ATR ETAA1	7.23e-06	2	94	2	30755469
Pubmed	Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia.	ATM NPAT	7.23e-06	2	94	2	8789452
Pubmed	Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM).	ATR ATM	7.23e-06	2	94	2	34151669
Pubmed	miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling.	MAGEA3 MAGEA6	7.23e-06	2	94	2	30056111
Pubmed	Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.	ATR ATM	7.23e-06	2	94	2	16213462
Pubmed	ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.	ATR ATM	7.23e-06	2	94	2	27442013
Pubmed	Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells.	ATR ATM	7.23e-06	2	94	2	24726882
Pubmed	rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis.	ATR ATM	7.23e-06	2	94	2	26061708
Pubmed	Ataxia-telangiectasia locus: sequence analysis of 184 kb of human genomic DNA containing the entire ATM gene.	ATM NPAT	7.23e-06	2	94	2	9199932
Pubmed	Functional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript.	ATR ATM	7.23e-06	2	94	2	20103595
Pubmed	Interplay between ATM and ATR in the regulation of common fragile site stability.	ATR ATM	7.23e-06	2	94	2	17934520
Pubmed	Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.	ATR ATM	7.23e-06	2	94	2	25483091
Pubmed	ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.	ATR ATM	7.23e-06	2	94	2	23592994
Pubmed	Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway.	ATR ATM	7.23e-06	2	94	2	19527713
Pubmed	ATM and ATR signaling at a glance.	ATR ATM	7.23e-06	2	94	2	26567218
Pubmed	RPA-Binding Protein ETAA1 Is an ATR Activator Involved in DNA Replication Stress Response.	ATR ETAA1	7.23e-06	2	94	2	27818175
Pubmed	Cancer genome datamining and functional genetic analysis implicate mechanisms of ATM/ATR dysfunction underpinning carcinogenesis.	ATR ATM	7.23e-06	2	94	2	33742106
Pubmed	Roles of ATM and ATR in DNA double strand breaks and replication stress.	ATR ATM	7.23e-06	2	94	2	33887296
Pubmed	ATR disruption leads to chromosomal fragmentation and early embryonic lethality.	ATR ATM	7.23e-06	2	94	2	10691732
Pubmed	Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription.	ATR ATM	7.23e-06	2	94	2	31114877
Pubmed	Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.	ATR ATM	7.23e-06	2	94	2	35011623
Pubmed	The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo.	ATR ATM	7.23e-06	2	94	2	26517239
Pubmed	DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress.	ATR ATM	7.23e-06	2	94	2	21593482
Pubmed	A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function.	ATR ATM	7.23e-06	2	94	2	25232030
Pubmed	ATM acts downstream of ATR in the DNA damage response signaling of bystander cells.	ATR ATM	7.23e-06	2	94	2	18757420
Pubmed	Cellular responses to the DNA strand-scission enediyne C-1027 can be independent of ATM, ATR, and DNA-PK kinases.	ATR ATM	7.23e-06	2	94	2	11927575
Pubmed	In Vivo and In Vitro Effects of ATM/ATR Signaling Pathway on Proliferation, Apoptosis, and Radiosensitivity of Nasopharyngeal Carcinoma Cells.	ATR ATM	7.23e-06	2	94	2	28820634
Pubmed	ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.	ATR ATM	7.23e-06	2	94	2	29279380
Pubmed	ATR regulates fragile site stability.	ATR ATM	7.23e-06	2	94	2	12526805
Pubmed	Interaction between HER2 and ATM predicts poor survival in bladder cancer patients.	ERBB2 ATM	7.23e-06	2	94	2	36056635
Pubmed	Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation.	ATR ATM	7.23e-06	2	94	2	24238855
Pubmed	Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex.	ATR ATM	7.23e-06	2	94	2	16474843
Pubmed	The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.	ATR ATM	7.23e-06	2	94	2	8843195
Pubmed	Viral DNA replication-dependent DNA damage response activation during BK polyomavirus infection.	ATR ATM	7.23e-06	2	94	2	25694603
Pubmed	Ataxia-Telangiectasia and RAD3-Related and Ataxia-Telangiectasia-Mutated Proteins in Epithelial Ovarian Carcinoma: Their Expression and Clinical Significance.	ATR ATM	7.23e-06	2	94	2	26124337
Pubmed	Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.	ATR ATM	7.23e-06	2	94	2	25812484
Pubmed	Roles of ATM and ATR-mediated DNA damage responses during lytic BK polyomavirus infection.	ATR ATM	7.23e-06	2	94	2	22952448
Pubmed	Identification of novel MAGE-A6- and MAGE-A12-derived HLA-A24-restricted cytotoxic T lymphocyte epitopes using an in silico peptide-docking assay.	MAGEA6 MAGEA12	7.23e-06	2	94	2	22707303
Pubmed	ATM regulates ATR chromatin loading in response to DNA double-strand breaks.	ATR ATM	7.23e-06	2	94	2	16461339
Pubmed	ATR localizes to the photoreceptor connecting cilium and deficiency leads to severe photoreceptor degeneration in mice.	ATR ATM	7.23e-06	2	94	2	23297361
Pubmed	Inactivation of ATM/ATR DNA damage checkpoint promotes androgen induced chromosomal instability in prostate epithelial cells.	ATR ATM	7.23e-06	2	94	2	23272087
Pubmed	The Dimeric Architecture of Checkpoint Kinases Mec1ATR and Tel1ATM Reveal a Common Structural Organization.	ATR ATM	7.23e-06	2	94	2	27129217
Pubmed	PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity.	SREBF1 PRKCI	7.23e-06	2	94	2	12975478
Pubmed	Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants.	ATR ATM	7.23e-06	2	94	2	20368801
Pubmed	Clinicopathological significance of ataxia telangiectasia-mutated (ATM) kinase and ataxia telangiectasia-mutated and Rad3-related (ATR) kinase in MYC overexpressed breast cancers.	ATR ATM	7.23e-06	2	94	2	30746633
Pubmed	Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses.	ATR ATM	7.23e-06	2	94	2	33640756
Pubmed	A role for ATR in the DNA damage-induced phosphorylation of p53.	ATR ATM	7.23e-06	2	94	2	9925639
Pubmed	Analysis of mutations that dissociate G(2) and essential S phase functions of human ataxia telangiectasia-mutated and Rad3-related (ATR) protein kinase.	ATR ATM	7.23e-06	2	94	2	21908846
Pubmed	The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication.	ATR ATM	7.23e-06	2	94	2	29263259
Pubmed	BCL9 and C9orf5 are associated with negative symptoms in schizophrenia: meta-analysis of two genome-wide association studies.	TMEM245 BCL9	7.23e-06	2	94	2	23382809
Pubmed	An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control.	ATR ATM	7.23e-06	2	94	2	23176708
Pubmed	The ATM- and ATR-related SCD domain is over-represented in proteins involved in nervous system development.	ATR ATM	7.23e-06	2	94	2	26743489
Pubmed	Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.	ATR ATM	7.23e-06	2	94	2	15533933
Pubmed	ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling.	ATR ATM	7.23e-06	2	94	2	17124492
Pubmed	A Comprehensive Expression Analysis of Cancer Testis Antigens in Head and Neck Squamous Cell Carcinoma Revels MAGEA3/6 as a Marker for Recurrence.	MAGEA3 MAGEA6	7.23e-06	2	94	2	25564441
Pubmed	ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation.	ATR ATM	7.23e-06	2	94	2	12519769
Pubmed	Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein.	NUAK1 ATM	7.23e-06	2	94	2	12409306
Pubmed	The association of ATR protein with mouse meiotic chromosome cores.	ATR ATM	7.23e-06	2	94	2	10382071
Pubmed	Structure, chromosomal localization, and expression of 12 genes of the MAGE family.	MAGEA3 MAGEA6 MAGEA12	8.50e-06	15	94	3	7927540
Pubmed	Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.	ATR ATM TBR1	8.50e-06	15	94	3	27073218
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	NRXN3 NUAK1 PPRC1 ADGRB3 PIP5K1C	1.01e-05	105	94	5	9628581
Pubmed	DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.	ATR ATM TBR1	1.04e-05	16	94	3	28123024
Pubmed	The functional interactome landscape of the human histone deacetylase family.	ZNF827 USP9X ANKRD11 TMPO RERE ADNP ZNF687	1.40e-05	289	94	7	23752268
Pubmed	Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development.	ATR ATM TBR1	1.51e-05	18	94	3	28620865
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LRIG3 ZHX3 FRMPD4 PPRC1 CAMTA2 RERE PIP5K1C SPEN	1.52e-05	407	94	8	12693553
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ATR DSP AHNAK TMPO ICE1 TBR1	1.90e-05	202	94	6	33005030
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDCA2 EHBP1 ERBB2 DSP AHNAK GTSE1 ANKRD11 AKAP11 PRKCI DOP1A OTOG	2.14e-05	861	94	11	36931259
Pubmed	ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.	ATR ATM	2.16e-05	3	94	2	26563132
Pubmed	Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study.	ATR ATM	2.16e-05	3	94	2	25846551
Pubmed	ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair.	ATR ATM	2.16e-05	3	94	2	23438602
Pubmed	Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.	ATR ATM	2.16e-05	3	94	2	18344416
Pubmed	Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.	ATR ATM	2.16e-05	3	94	2	9766667
Pubmed	Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.	ATR ATM	2.16e-05	3	94	2	27625305
Pubmed	Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility.	ATR ATM	2.16e-05	3	94	2	18451257
Pubmed	A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.	ATR ATM	2.16e-05	3	94	2	12773400
Pubmed	DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells.	ATR ATM	2.16e-05	3	94	2	27733644
Pubmed	Regulation of HER2 oncogene transcription by a multifunctional coactivator/corepressor complex.	ERBB2 ANKRD11	2.16e-05	3	94	2	24678732
Pubmed	Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.	ATR ATM	2.16e-05	3	94	2	11114888
Pubmed	Effect of ATM, CHEK2 and ERBB2 TAGSNPs and haplotypes on endometrial cancer risk.	ERBB2 ATM	2.16e-05	3	94	2	17164260
Interaction	HDAC1 interactions	EHBP1 MAGEA3 ZHX3 MRTFB ERCC6 WIZ ATR ZNF827 AHNAK SREBF1 ATM PRKG1 RERE ADNP SPEN ZNF687 NPAT	1.11e-05	1108	93	17	int:HDAC1
Interaction	SMC5 interactions	CDCA2 ZHX3 RAD51AP1 WIZ DSP ATAD5 AHNAK GTSE1 MARF1 ANKRD11 TMPO ICE1 ADNP SPEN HDGFL2 NPAT	1.25e-05	1000	93	16	int:SMC5
Interaction	CHD4 interactions	MAGEA3 ERCC6 WIZ ATR ZNF827 DSP MTF1 AHNAK TMPO PRKCI ATM ADNP SPEN HDGFL2 ZNF687	2.43e-05	938	93	15	int:CHD4
Cytoband	11q22-q23	ATM NPAT	6.19e-05	6	94	2	11q22-q23
Cytoband	19q13.3-q13.4	SCAF1 IRF3	3.19e-04	13	94	2	19q13.3-q13.4
GeneFamily	MAGE family	MAGEA3 MAGEA6 MAGEA12	2.06e-04	40	52	3	1136
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R3A PPP2R5D	8.32e-04	15	52	2	696
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZHX3 ADNP	8.32e-04	15	52	2	529
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP5 APPL2	1.07e-03	17	52	2	1291
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AGAP5 APPL2 FGD1 PLEKHG5	2.89e-03	206	52	4	682
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	SYNM AKAP11	3.13e-03	29	52	2	396
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	EHBP1 ZHX3 PPP2R3A ATR NUAK1 BMP2K USP9X TMEM131L AKAP11 PRKCI ADNP PNISR SPEN MEIS2 NPAT	3.82e-07	856	94	15	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	EHBP1 ZHX3 PPP2R3A ATR NUAK1 USP9X MARF1 PRKCI PNISR SPEN MEIS2	9.14e-07	466	94	11	M13522
Coexpression	GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP	LMAN1L CD19 MARF1 TMEM131L ICE1 C2orf68 DOP1A	7.92e-06	200	94	7	M6447
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	PPRC1 TMEM131L ICE1 ADNP PNISR SPEN DOP1A NPAT	1.27e-05	300	94	8	M8702
Coexpression	IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN	EHBP1 NUAK1 TMEM245 PRKCI PALMD	4.24e-05	107	94	5	M4913
Coexpression	FOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_UP	MAGEA3 MAGEA6 MRTFB FRMPD4 DSP USP9X TMPO ICE1 ATM ADGRG4	4.92e-05	587	94	10	M40869
Coexpression	GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN	AHNAK GTSE1 MARF1 ATM PNISR C2orf68	7.42e-05	195	94	6	M7410
Coexpression	HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP	MAGEA6 MAGEA12 MAF	7.51e-05	23	94	3	M1184
Coexpression	GENTILE_UV_LOW_DOSE_DN	EHBP1 PPP2R3A MARF1 MEIS2	8.36e-05	64	94	4	M4594
Coexpression	HADDAD_B_LYMPHOCYTE_PROGENITOR	ATR CD19 TMEM131L CD69 ATM PNISR SNTB2	8.50e-05	290	94	7	M939
Coexpression	GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_DN	APPL2 DSP SREBF1 OS9 CAMTA2 BCL9	8.54e-05	200	94	6	M4352
Coexpression	HE_LIM_SUN_FETAL_LUNG_C7_PROLIFERATING_SCHWANN_CELL	CDCA2 RAD51AP1 ERBB2 NRXN3 BMP2K SYNM TMEM245 GTSE1 SREBF1 IRF3 AKAP11 MAF NPAT	9.82e-05	1054	94	13	M45798
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_2_CELL	CDCA2 LRIG3 RAD51AP1 ATAD5 GTSE1 TMTC2 MEIS2	1.05e-04	300	94	7	M45675
Coexpression	VERNELL_RETINOBLASTOMA_PATHWAY_UP	RAD51AP1 TMPO SNTB2 NPAT	1.12e-04	69	94	4	M15969
Coexpression	VERRECCHIA_RESPONSE_TO_TGFB1_C6	IGFBP4 DSP	1.26e-04	5	94	2	M15374
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	EHBP1 PRUNE2 ZHX3 ANKRD11 RERE PNISR	1.47e-04	221	94	6	M39222
Coexpression	ZWANG_DOWN_BY_2ND_EGF_PULSE	CDCA2 TMTC4 CIART GTSE1 ADGRB3 ZNF79 ZNF687	1.59e-04	321	94	7	M2615
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 IGFBP4 NUAK1 SYNM TMEM131L PRKG1 MEIS2	7.54e-08	170	94	7	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 IGFBP4 NUAK1 SYNM TMEM131L PRKG1 MEIS2	7.54e-08	170	94	7	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 IGFBP4 NUAK1 SYNM TMEM131L PRKG1 MEIS2	7.54e-08	170	94	7	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDCA2 MRTFB NUAK1 PALMD MEIS2 MEOX1	1.29e-06	163	94	6	ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRXN3 IGFBP4 SYNM TMEM131L PRKG1 MEIS2	2.22e-06	179	94	6	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MRTFB IGFBP4 NUAK1 PALMD MEIS2 MEOX1	2.45e-06	182	94	6	3cbeaf7904a76c32137a00abb20e302d3d3c8bb8
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 MRTFB IGFBP4 NUAK1 PRKG1 C16orf89	2.45e-06	182	94	6	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 MRTFB IGFBP4 NUAK1 PRKG1 C16orf89	2.45e-06	182	94	6	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZBTB7C IGFBP4 NUAK1 TMTC2 PALMD MEOX1	2.52e-06	183	94	6	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRTFB IGFBP4 NUAK1 PALMD MEIS2 C16orf89	2.52e-06	183	94	6	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CDCA2 PRUNE2 RAD51AP1 ERCC6 GTSE1 MEIS2	2.77e-06	186	94	6	5cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LURAP1L NRXN3 ZBTB7C ADGRB3 TMEM131L PRKG1	2.86e-06	187	94	6	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LURAP1L NRXN3 ZBTB7C ADGRB3 TMEM131L PRKG1	2.86e-06	187	94	6	530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C IGFBP4 ADGRB3 PALMD MEIS2 MEOX1	3.13e-06	190	94	6	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C IGFBP4 NUAK1 ADGRB3 TMTC2 MEIS2	3.33e-06	192	94	6	1ee4783051ec94ea94600f040edcb385fc4289f1
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 SYNM DSP AHNAK PACSIN2 MAF	3.33e-06	192	94	6	b016e229300c183e14c0e2bba494bf49c7899112
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 ZBTB7C SYNM TMEM131L PRKG1 MEIS2	3.33e-06	192	94	6	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 SYNM DSP AHNAK PACSIN2 MAF	3.33e-06	192	94	6	ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 ZBTB7C SYNM TMEM131L PRKG1 MEIS2	3.33e-06	192	94	6	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO MAF	3.43e-06	193	94	6	b835d28de9daeec5213172c96f62b332cda53bb5
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRTFB NUAK1 SYNM MAP3K7CL PALMD C16orf89	3.53e-06	194	94	6	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MRTFB IGFBP4 NUAK1 PALMD MEIS2 MEOX1	3.75e-06	196	94	6	a0ba408b802fa6d6e42e6d234b6879fdb1583f81
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Large_pre-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CDCA2 RAD51AP1 CD19 ATAD5 GTSE1 TMPO	3.86e-06	197	94	6	cebf47d66f425c84d3fea962e11f5bf4bfe2e60f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LURAP1L ADGRB3 TMTC2 PRKG1 CDH4 MAF	3.86e-06	197	94	6	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	ASK428-Endothelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	IGFBP4 NUAK1 SYNM DSP PALMD MEIS2	3.97e-06	198	94	6	d69d0ff115298596173a4278897a65007a71f5df
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	ZHX3 PPP2R3A MRTFB NUAK1 PALMD MEOX1	3.97e-06	198	94	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	ILEUM-non-inflamed-(7)_ACKR1+_endothelial_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MRTFB IGFBP4 NUAK1 PALMD MEIS2 MEOX1	3.97e-06	198	94	6	f8a6a75c9f2fbe32a22b14b6a029411c73c09f68
ToppCell	PSB\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PRUNE2 NRXN3 DSP MUC15 PALMD C16orf89	3.97e-06	198	94	6	4e6b0d1abc55d7a0d89bd7ecf0f13dc5bed66626
ToppCell	(5)_Dendritic_cell-(52)_cycling_DCs\|(5)_Dendritic_cell / shred on Cell_type and subtype	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO MAF	4.09e-06	199	94	6	d0ff446a197062b10f37b585f3f8716d6d89e5b7
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO MEIS2	4.09e-06	199	94	6	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	cellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MRTFB IGFBP4 NUAK1 PALMD MEIS2 MEOX1	4.21e-06	200	94	6	a1f5684fe3815642159dd201b7ecc39f09bee1e8
ToppCell	Sigmoid-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	RAD51AP1 APPL2 ATAD5 GTSE1 ANKRD11 MAF	4.21e-06	200	94	6	372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCell	Biopsy_IPF-Immune-Proliferating_T_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO CD69	4.21e-06	200	94	6	c43d1a83b2a8ad060f3d80c9438da8b7a5e307fb
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD19 DSP MARF1 TMEM131L ADGRG4	8.64e-06	131	94	5	a3a086ce6e69707ca6a042f3b15c130f81909acb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C IGFBP4 NUAK1 ADGRB3 MEIS2	1.95e-05	155	94	5	babcb9e548f04ace8157d506d27c5941c692c491
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MRTFB NUAK1 PALMD MEIS2 MEOX1	2.48e-05	163	94	5	977a970b1296234c22178420294cea73506ee02f
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BMP2K DSP PPRC1 FGD1 MAF	2.63e-05	165	94	5	94a5211072464fc24592bb107a853ce832e816fe
ToppCell	Endothelial-endothelial_cell_of_bronchial_vessel\|World / Lineage, Cell type, age group and donor	MRTFB NUAK1 PALMD MEIS2 MEOX1	2.63e-05	165	94	5	84e553d699ac56df89a77248f7308b9133e1b683
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C IGFBP4 NUAK1 ADGRB3 PLEKHG5	2.71e-05	166	94	5	9d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	EHBP1 BMP2K ZNF79 PIP5K1C MEIS2	2.87e-05	168	94	5	2fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	PRUNE2 MRTFB ZBTB7C PRKG1 PACSIN2	3.12e-05	171	94	5	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	3.21e-05	172	94	5	8d20eda599abf1e9e3e3b90f314acddee6a465a4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 ZBTB7C SYNM TMEM131L PRKG1	3.49e-05	175	94	5	d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CDCA2 RAD51AP1 ATAD5 GTSE1 DAB1	3.49e-05	175	94	5	0b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 ZBTB7C SYNM TMEM131L PRKG1	3.49e-05	175	94	5	454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CDCA2 RAD51AP1 ATAD5 GTSE1 PRKG1	3.68e-05	177	94	5	844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CDCA2 RAD51AP1 ATAD5 GTSE1 PRKG1	3.68e-05	177	94	5	26c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCell	IIH-CD8-antiviral_CD4\|IIH / Condition, Cell_class and T cell subcluster	PPP2R3A ERCC6 TMTC4 MAP3K7CL PIP5K1C	3.68e-05	177	94	5	fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 MRTFB IGFBP4 NUAK1 C16orf89	3.78e-05	178	94	5	9f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	CDCA2 PRUNE2 RAD51AP1 ERCC6 GTSE1	3.89e-05	179	94	5	ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	IGFBP4 NUAK1 ADGRB3 PRKG1 MEIS2	3.89e-05	179	94	5	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 MRTFB NUAK1 PRKG1 C16orf89	3.99e-05	180	94	5	67c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRTFB IGFBP4 NUAK1 PALMD MEIS2	4.10e-05	181	94	5	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 MRTFB NUAK1 PRKG1 C16orf89	4.10e-05	181	94	5	4ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	4.20e-05	182	94	5	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 MRTFB IGFBP4 NUAK1 C16orf89	4.20e-05	182	94	5	aa113a0d2c1d28bda24cbb1221afd21b5628dc6d
ToppCell	droplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNM RTL1 PALMD MEIS2 C16orf89	4.20e-05	182	94	5	f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	4.32e-05	183	94	5	a48a6313f2f144586951cece97ec31f6d72361df
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	IGFBP4 CD19 BMP2K DSP DOP1A	4.32e-05	183	94	5	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	IGFBP4 NUAK1 ADGRB3 PALMD MEIS2	4.32e-05	183	94	5	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	Control-Endothelial_cells-Pulmonary_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	MRTFB NUAK1 PALMD MEIS2 SNTB2	4.32e-05	183	94	5	46be9f96755c7b65aeac061d95d15abeb6466034
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	CDCA2 RAD51AP1 PPRC1 ATAD5 GTSE1	4.32e-05	183	94	5	a716b446c2bf5aa294b8f580aa845098fae76354
ToppCell	normal_Lung-Endothelial_cells-Tumor_ECs\|normal_Lung / Location, Cell class and cell subclass	FRMPD4 IGFBP4 NUAK1 PALMD MEOX1	4.43e-05	184	94	5	7ee98acda030366ac6cf3890a6d93fd0426712ed
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZBTB7C IGFBP4 NUAK1 PRKG1 C16orf89	4.43e-05	184	94	5	f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZBTB7C IGFBP4 NUAK1 PRKG1 C16orf89	4.43e-05	184	94	5	8bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	NRXN3 IGFBP4 NUAK1 PALMD MEIS2	4.43e-05	184	94	5	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAD51AP1 CNNM1 GTSE1 TMPO MAP3K7CL	4.43e-05	184	94	5	d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 ADGRB3 TMEM131L PRKG1 MEIS2	4.54e-05	185	94	5	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LURAP1L NRXN3 FRMPD4 SYNM PRKG1	4.54e-05	185	94	5	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	facs-Lung-Endomucin-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRTFB IGFBP4 MARF1 PALMD C16orf89	4.54e-05	185	94	5	f262b441ea3fe7f69dff33d5f171000371f3a3e5
ToppCell	Endothelial-A-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	MRTFB IGFBP4 NUAK1 PALMD MEIS2	4.54e-05	185	94	5	dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 ADGRB3 TMEM131L PRKG1 MEIS2	4.54e-05	185	94	5	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRMPD4 ZBTB7C NUAK1 PALMD MEIS2	4.66e-05	186	94	5	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 MRTFB IGFBP4 NUAK1 C16orf89	4.66e-05	186	94	5	5302399825f213d105ac70b91366a4513b732838
ToppCell	droplet-Kidney-nan-3m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTL1 PALMD MEIS2 MEOX1 C16orf89	4.78e-05	187	94	5	d72012e94857606f39975cf672f6b8c2e0fe093e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDCA2 RAD51AP1 ATAD5 GTSE1 CD69	4.78e-05	187	94	5	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	10x5'-Liver-Lymphocytic_NK-Cycling_NK\|Liver / Manually curated celltypes from each tissue	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	4.91e-05	188	94	5	5eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCell	Endothelial-Endothelial-E\|Endothelial / shred on cell class and cell subclass (v4)	NRXN3 IGFBP4 NUAK1 MEIS2 C16orf89	4.91e-05	188	94	5	2777eb7689b271c199021fe7d9db88ccebff14de
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	4.91e-05	188	94	5	319fbeca200ab998daf49fcaee0bfdb57bf7ee4b
ToppCell	MatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)\|MatrixFB / shred on cell class and cell subclass (v4)	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	4.91e-05	188	94	5	b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 ZBTB7C TMEM131L PRKG1 MEIS2	5.03e-05	189	94	5	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	MRTFB IGFBP4 NUAK1 PALMD MEOX1	5.03e-05	189	94	5	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	droplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NUAK1 PALMD MEIS2 C16orf89	5.03e-05	189	94	5	2ce330d8078833c05775c481e73770f9ee4a5c88
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRIG3 MRTFB PRKG1 PALMD MEIS2	5.03e-05	189	94	5	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 ZBTB7C TMEM131L PRKG1 MEIS2	5.03e-05	189	94	5	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	Endothelial-A-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	MRTFB IGFBP4 NUAK1 PALMD MEOX1	5.03e-05	189	94	5	04b565855f58ca0f343904d04be657b66e109076
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NUAK1 PALMD MEIS2 C16orf89	5.03e-05	189	94	5	473c87036e04a058b4a5138438b7ba7e1e766799
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	5.03e-05	189	94	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDCA2 RAD51AP1 ATAD5 GTSE1 MEIS2	5.16e-05	190	94	5	31de1727822e9818652946dfb962daee77ffad68
ToppCell	343B-Endothelial_cells-Endothelial-A_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	MRTFB FRMPD4 NUAK1 PALMD MEOX1	5.16e-05	190	94	5	ac2eb1e51459d187095152e0cd41ae54c1025c6f
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZBTB7C IGFBP4 NUAK1 MEIS2 C16orf89	5.16e-05	190	94	5	3b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCell	normal_Pleural_Fluid-T/NK_cells-Undetermined\|normal_Pleural_Fluid / Location, Cell class and cell subclass	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	5.16e-05	190	94	5	165c61443ff0c8efbdad3b052bb00f46d81c5203
ToppCell	Caecum-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	CDCA2 GTSE1 TMPO AKAP11 MAF	5.16e-05	190	94	5	54463f6f1718f22704175bd034f134de3b55d2eb
ToppCell	343B-Endothelial_cells-Endothelial-A_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	MRTFB FRMPD4 NUAK1 PALMD MEOX1	5.16e-05	190	94	5	6010f16378f2d9cde37c7e7db6a7d9666edaddcc
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	5.16e-05	190	94	5	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	IGFBP4 SYNM TMEM131L PRKG1 MEIS2	5.29e-05	191	94	5	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CDCA2 RAD51AP1 ATAD5 GTSE1 TMPO	5.29e-05	191	94	5	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EHBP1 AHNAK PRKG1 CDH4 MAF	5.29e-05	191	94	5	fa380a8752de158974b2ae5e741573439719cc0d
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 MRTFB IGFBP4 NUAK1 C16orf89	5.29e-05	191	94	5	6e6b2cb390cc5cd0356924a2c36fbe5b5bd5966c
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	MRTFB IGFBP4 NUAK1 PALMD MEIS2	5.29e-05	191	94	5	617546cf4883dedf3323e03a53ba5adec334cf8e
Drug	AC1N9ZLR	ERBB2 IGFBP4 CD19 SREBF1 ANKRD11 CD69 ZNF79 RERE	2.77e-06	212	94	8	CID004369063
Drug	Berberine chloride [633-65-8]; Down 200; 10.8uM; PC3; HT_HG-U133A	ZHX3 PPP2R3A PPP2R5D ERCC6 ATAD5 FGD1 PNISR	1.71e-05	196	94	7	7143_DN
Drug	Alexidine dihydrochloride [22573-93-9]; Down 200; 6.8uM; PC3; HT_HG-U133A	ZHX3 CNNM1 NRXN3 ATAD5 TMPO PALMD PNISR	1.71e-05	196	94	7	3699_DN
Drug	Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A	PPP2R5D BMP2K ETAA1 FGD1 ZNF79 ATM PIP5K1C	1.77e-05	197	94	7	5503_DN
Drug	Betazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A	PPP2R3A BMP2K MTF1 ANKRD11 BCL9 PNISR NPAT	1.83e-05	198	94	7	1690_DN
Drug	Guanadrel sulfate [22195-34-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A	PPP2R3A WIZ BMP2K ATAD5 ATM PIP5K1C C2orf68	1.95e-05	200	94	7	3438_DN
Disease	ataxia telangiectasia (implicated_via_orthology)	ATR ATM	9.20e-06	2	90	2	DOID:12704 (implicated_via_orthology)
Disease	Benign neoplasm of stomach	ERBB2 ATR ATM	1.81e-05	17	90	3	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ERBB2 ATR ATM	1.81e-05	17	90	3	C0496905
Disease	Carcinoma in situ of stomach	ERBB2 ATR ATM	1.81e-05	17	90	3	C0154060
Disease	Stomach Carcinoma	ERBB2 ATR ATM	3.51e-05	21	90	3	C0699791
Disease	Neoplasm of uncertain or unknown behavior of ovary	ERBB2 ERCC6 ATR	9.47e-05	29	90	3	C0496920
Disease	Ovarian Carcinoma	ERBB2 ERCC6 ATR	1.05e-04	30	90	3	C0029925
Disease	Neurodevelopmental Disorders	PPP2R5D ANKRD11 TBR1 ADNP	1.92e-04	93	90	4	C1535926
Disease	blood phosphate measurement	ZHX3 RAD51AP1 PPP2R3A OS9 MAF	1.97e-04	174	90	5	EFO_0010972
Disease	nasopharynx carcinoma (is_marker_for)	ATR ATM SPEN	3.10e-04	43	90	3	DOID:9261 (is_marker_for)
Disease	underweight body mass index status	NRXN3 ADGRB3	3.27e-04	9	90	2	EFO_0005936
Disease	ovarian neoplasm	ERBB2 ERCC6 ATR BCL9	7.68e-04	134	90	4	C0919267
Disease	Lung cancer	ERBB2 ERCC6	8.17e-04	14	90	2	cv:C0242379
Disease	LUNG CANCER	ERBB2 ERCC6	8.17e-04	14	90	2	211980
Disease	Neoplasm of lung	ERBB2 ERCC6	8.17e-04	14	90	2	cv:C0024121
Disease	Malignant neoplasm of ovary	ERBB2 ERCC6 ATR BCL9	8.34e-04	137	90	4	C1140680
Disease	Autistic Disorder	NRXN3 MTF1 DAB1 TBR1 ADNP	1.24e-03	261	90	5	C0004352
Disease	waist-hip ratio	CDCA2 PRUNE2 ZHX3 SEC16B PPP2R3A NRXN3 ZBTB7C AHNAK ETAA1 RERE MEIS2	1.26e-03	1226	90	11	EFO_0004343
Disease	thyroid peroxidase antibody measurement	TMEM131L RERE MAF	1.41e-03	72	90	3	EFO_0005666
Disease	leukemia (implicated_via_orthology)	ATM MEIS2	1.52e-03	19	90	2	DOID:1240 (implicated_via_orthology)
Disease	Carcinoma of lung	ERBB2 ERCC6	2.23e-03	23	90	2	C0684249
Disease	Glioma	ERBB2 ATR ATM	2.42e-03	87	90	3	C0017638
Disease	Pseudoaphakia	ERCC6 ATM	2.43e-03	24	90	2	C0524524
Disease	lateral orbital frontal cortex volume measurement	DAB1 OTOG	2.43e-03	24	90	2	EFO_0010312
Disease	Lens Opacities	ERCC6 ATM	2.43e-03	24	90	2	C1510497

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSEQADFSLAQPDSP	nan	56	Q6ZRG5
NLEEESNESGSPFDP	ADNP	881	Q9H2P0
AADPVPSFDESSQDT	ATAD5	806	Q96QE3
FLPESFDGDPASNTA	ERBB2	376	P04626
PTFGPQDSFSEERSD	C16orf89	146	Q6UX73
PSFAPSSSVDGNNTD	ANKRD11	306	Q6UB99
SAQGTPSEISFPNDD	ADGRG4	3056	Q8IZF6
QDPINADSSSSFPNG	ADGRB3	1166	O60242
SSESPSDNQAFQAPG	C1orf216	61	Q8TAB5
ASDDGAAPEDADSPQ	CAMTA2	916	O94983
SSNPTGAEFDPEEDE	PPP2R5D	186	Q14738
NSFSDEREFSGPSTP	AHNAK	5781	Q09666
EDNLSFPTSDSDGPD	AKAP11	1776	Q9UKA4
FEDGENPPSSRSSES	DOP1A	586	Q5JWR5
GNDESESDFESDPPS	BMP2K	736	Q9NSY1
PRNPDYEESGESSSS	C2orf68	81	Q2NKX9
DSANDTEPDFAPGED	RAD51AP1	191	Q96B01
SPNGQDPEDGDSTAS	MEOX1	236	P50221
SFETEESDGQSGQPA	NPAT	371	Q14207
PESGQENDATSPHFS	CD69	16	Q07108
GSDAESDSDDPSYAP	ERCC6	536	P0DP91
DDFSSPSITNEFGAP	GGT3P	421	A6NGU5
PFDAQTTGDGTEDPS	PALMD	521	Q9NP74
SPFDIVGSSDNPDQN	PRKCI	451	P41743
FRENGSSSDNPSSPE	MAF	356	O75444
DSSNQEEEGPSTFPD	MAGEA3	86	P43357
DSSNQEEEGPSTFPD	MAGEA6	86	P43360
GSSNEEQEGPSTFPD	MAGEA12	86	P43365
GTNSKGPPDFSSDEE	TMPO	56	P42166
DNAPEPYDVSFGNSS	MUC15	286	Q8N387
DFSANPEPASVASSN	LRIG3	1021	Q6UXM1
ASPTDTSNFDSFPED	PRKG1	641	Q13976
TSNFDSFPEDNDEPP	PRKG1	646	Q13976
IFFDSPAEDTQDSPA	LMAN1L	136	Q9HAT1
DNSVASPGTGDDDDP	MEIS2	256	O14770
FDEDSSDALSPDQPA	MRTFB	176	Q9ULH7
GTNSKGPPDFSSDEE	TMPO	56	P42167
TDEPASPSEFGNKSN	PPP2R3A	1116	Q06190
PQALNFSPEESDSTF	GTSE1	586	Q9NYZ3
SDSEAPEANPADGSD	HDGFL2	101	Q7Z4V5
SSFSSPNDPDGQNDI	ETAA1	91	Q9NY74
PFSSTDANGDSNPFD	PACSIN2	406	Q9UNF0
YPDSSVSDANEPGES	ATM	861	Q13315
PLFQHSPGDSSQEDS	ATR	1866	Q13535
DFNSPGGSSPVENSD	ICE1	936	Q9Y2F5
EAPDGSQASSNSDPF	DAB1	556	O75553
PLGPEDEDSFSNAES	CD19	446	P15391
PPGFRDSSDEEDSQS	FRMPD4	811	Q14CM0
DSFDQRDPGTPNDDS	BCL9	106	O00512
SDPSDDTKGFFDPNT	DSP	2406	P15924
GPSQDDSLQAFSSPS	FAM131C	201	Q96AQ9
NDNPPEFTASTFAGE	CDH4	386	P55283
TNPFGETEDESFPEA	APPL2	471	Q8NEU8
DLATVNSNPFDDPDA	EHBP1	261	Q8NDI1
PGHQTPSDLDQFSDS	LURAP1L	191	Q8IV03
NSSSEADCPDPFANG	MARF1	776	Q9Y4F3
DPENSQGPAAGSSDE	CDCA2	956	Q69YH5
DNADSENLSPFDSIP	PPRC1	136	Q5VV67
VFDDDSGNPSPESFL	OTOG	1051	Q6ZRI0
NSGVGDFSQPDTSPD	IRF3	111	Q14653
AFSLNDASDDTPPED	MAP3K7CL	16	P57077
FNPKEADDETSDQPS	RTL1	566	A6NKG5
PAGAPLADDSSDFQF	USP9X	1101	Q93008
NQSDTDNFPDSKDSP	TBR1	61	Q16650
SPADDFFPNSDLSEG	PRUNE2	516	Q8WUY3
PAGDSVSQNDFPSEA	TMEM131L	1346	A2VDJ0
TQSPETEASADSFPD	SYNM	651	O15061
PDAPYDSDSGESQAS	BMT2	376	Q1RMZ1
SFNGDAESVSDVPPS	MTF1	396	Q14872
SGETFDSNLPPTDDE	NRXN3	406	Q9HDB5
GAPASQASDEEDAPA	PIP5K1C	621	O60331
PSNSEETCFVSDDGP	FGD1	291	P98174
DFAQSGQDAVPESPS	NUAK1	376	O60285
DSPDPSSQSAAAGAN	PROSER3	136	Q2NL68
YEEDPASQPGTSQDA	WIZ	451	O95785
PSPQDNESDSDSSAQ	RERE	716	Q9P2R6
SDKDEGDHPNNSFSP	IGFBP4	116	P22692
SPEAADSASGAPNDF	OS9	336	Q13438
NPSPGSADGDKEFSD	SREBF1	821	P36956
TDALEFNPSANPEAS	AGAP5	96	A6NIR3
TSPVNSDFGFPSDSE	CIART	21	Q8N365
DSSPQSPDMEAFTDG	CNNM1	796	Q9NRU3
DPDPDSSNSGFDSSV	CNOT11	246	Q9UKZ1
PPDNAAGEFTDEDSG	PGBD2	46	Q6P3X8
SSPEFDSGPFSSQSD	PLEKHG5	771	O94827
PAFTEVDNPASFADS	TMTC4	296	Q5T4D3
SFSQAESNVDPEPDS	SPEN	1741	Q96T58
DDNSLSQDFPGDESP	SCAF1	306	Q9H7N4
PSFSNSDNPAADSDS	TMTC2	251	Q8N394
ASPAGDEDSSDSPDS	SEC16B	926	Q96JE7
PSNSASEEESGKPFQ	ZNF827	361	Q17R98
GYESSSEDQPSTQPA	TMEM245	291	Q9H330
SDTPRDFPDSFQAGS	ZBTB7C	201	A1YPR0
SPQSPSSGAEAADED	ZNF687	301	Q8N1G0
PPSEDSNSQDSGEFA	PNISR	121	Q8TF01
EGAAPQSPSFSGSED	SNTB2	216	Q13425
EASSEPFDTSSPQAG	ZHX3	936	Q9H4I2
GSPPEQALSEASFQD	ZNF79	116	Q15937