Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponenttranslation release factor complex

GSPT2 GSPT1

5.24e-053882GO:0018444
DomainDrf_GBD

FMNL3 DIAPH1 FMNL2 FMNL1

4.72e-089844PF06371
DomainFH3_dom

FMNL3 DIAPH1 FMNL2 FMNL1

4.72e-089844IPR010472
DomainGTPase-bd

FMNL3 DIAPH1 FMNL2 FMNL1

4.72e-089844IPR010473
DomainDrf_FH3

FMNL3 DIAPH1 FMNL2 FMNL1

4.72e-089844PF06367
DomainDrf_FH3

FMNL3 DIAPH1 FMNL2 FMNL1

4.72e-089844SM01139
DomainDrf_GBD

FMNL3 DIAPH1 FMNL2 FMNL1

4.72e-089844SM01140
DomainGBD/FH3_dom

FMNL3 DIAPH1 FMNL2 FMNL1

1.23e-0711844IPR014768
DomainGBD_FH3

FMNL3 DIAPH1 FMNL2 FMNL1

1.23e-0711844PS51232
DomainFH2

FMNL3 DIAPH1 FMNL2 FMNL1

5.00e-0715844PS51444
DomainFH2_Formin

FMNL3 DIAPH1 FMNL2 FMNL1

5.00e-0715844IPR015425
DomainFH2

FMNL3 DIAPH1 FMNL2 FMNL1

5.00e-0715844PF02181
DomainFH2

FMNL3 DIAPH1 FMNL2 FMNL1

5.00e-0715844SM00498
DomainDAD_dom

DIAPH1 FMNL2 FMNL1

4.84e-068843IPR014767
DomainDAD

DIAPH1 FMNL2 FMNL1

4.84e-068843PS51231
DomainTransl_elong_EFTu/EF1A_C

GSPT2 GSPT1

5.50e-048842IPR004160
DomainGTP_EFTU_D3

GSPT2 GSPT1

5.50e-048842PF03143
DomainG_TR_CS

GSPT2 GSPT1

7.05e-049842IPR031157
DomainARM-type_fold

FMNL3 USP9X DIAPH1 USP9Y TRRAP FMNL2 FMNL1

8.35e-04339847IPR016024
DomainTransl_elong_EF1A/Init_IF2_C

GSPT2 GSPT1

8.79e-0410842IPR009001
DomainG_TR_1

GSPT2 GSPT1

1.51e-0313842PS00301
Domainzf-C2H2_6

ZNF675 ZNF10 ZNF718 ZNF302 ZNF850 ZNF726

2.92e-03314846PF13912
DomainPI3/4_kinase_cat_dom

PI4K2B TRRAP

2.92e-0318842IPR000403
DomainPI3_PI4_kinase

PI4K2B TRRAP

2.92e-0318842PF00454
DomainPI3_4_KINASE_3

PI4K2B TRRAP

2.92e-0318842PS50290
DomainEFTu-like_2

GSPT2 GSPT1

2.92e-0318842IPR004161
DomainPI3_4_KINASE_1

PI4K2B TRRAP

2.92e-0318842PS00915
DomainPI3_4_KINASE_2

PI4K2B TRRAP

2.92e-0318842PS00916
DomainGTP_EFTU_D2

GSPT2 GSPT1

2.92e-0318842PF03144
DomainG_TR_2

GSPT2 GSPT1

2.92e-0318842PS51722
DomainTF_GTP-bd_dom

GSPT2 GSPT1

3.25e-0319842IPR000795
Domain2OG-FeII_Oxy

PLOD3 ALKBH3

3.25e-0319842PF03171
DomainHis_PPase_superfam

PPIP5K2 UBASH3A

3.60e-0320842IPR029033
DomainPWWP

MSH6 ZMYND11

3.60e-0320842SM00293
Domain-

PPIP5K2 UBASH3A

3.60e-03208423.40.50.1240
DomainFE2OG_OXY

PLOD3 ALKBH3

3.97e-0321842PS51471
DomainPWWP

MSH6 ZMYND11

4.76e-0323842PF00855
DomainPWWP_dom

MSH6 ZMYND11

4.76e-0323842IPR000313
DomainOxoglu/Fe-dep_dioxygenase

PLOD3 ALKBH3

4.76e-0323842IPR005123
DomainPWWP

MSH6 ZMYND11

5.17e-0324842PS50812
DomainKRAB

ZNF675 ZNF10 ZNF718 ZNF302 ZNF850 ZNF726

5.52e-03358846PS50805
DomainKRAB

ZNF675 ZNF10 ZNF718 ZNF302 ZNF850 ZNF726

5.52e-03358846PF01352
Pubmed

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

FMNL3 DIAPH1 FMNL2 PHIP FMNL1

1.05e-082988521834987
Pubmed

Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.

FMNL3 FMNL2 FMNL1

1.57e-08388312684686
Pubmed

Expression of multiple formins in adult tissues and during developmental stages of mouse brain.

FMNL3 DIAPH1 FMNL2 FMNL1

3.76e-081488426272686
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MSH6 ZMYND11 MAP1A INTS13 IL21R DIAPH1 GRB2 FIP1L1 TRAF3IP3 BRMS1L TRRAP FMNL2 PHIP

4.61e-061116881331753913
Pubmed

Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1.

DIAPH1 FMNL1

6.33e-06288216943183
Pubmed

Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation.

GSPT2 GSPT1

6.33e-06288215987998
Pubmed

Hook2 localizes to the centrosome, binds directly to centriolin/CEP110 and contributes to centrosomal function.

CNTRL HOOK2

6.33e-06288217140400
Pubmed

Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.

USP9X USP9Y

6.33e-06288212925892
Pubmed

FMNL formins boost lamellipodial force generation.

FMNL3 FMNL2

6.33e-06288228327544
Pubmed

Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.

USP9X USP9Y

6.33e-06288212895410
Pubmed

A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.

FMNL3 FMNL2

6.33e-06288231751425
Pubmed

Protein N-myristoylation is required for cellular morphological changes induced by two formin family proteins, FMNL2 and FMNL3.

FMNL3 FMNL2

6.33e-06288222790947
Pubmed

Critical roles for multiple formins during cardiac myofibril development and repair.

FMNL2 FMNL1

6.33e-06288224430873
Pubmed

Formins regulate actin filament flexibility through long range allosteric interactions.

DIAPH1 FMNL2

6.33e-06288216490788
Pubmed

Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton.

GSPT2 GSPT1

6.33e-06288224981173
Pubmed

Formin and capping protein together embrace the actin filament in a ménage à trois.

DIAPH1 FMNL2

6.33e-06288226564775
Pubmed

The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

USP9X USP9Y

6.33e-0628828922996
Pubmed

The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.

KCTD19 PDE6B USP9X GRB2 GRIN1 PHIP

1.19e-0519988636688959
Pubmed

Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1.

GSPT2 GSPT1

1.90e-0538829712840
Pubmed

FMNL1 and mDia1 promote efficient T cell migration through complex environments via distinct mechanisms.

DIAPH1 FMNL1

1.90e-05388239430739
Pubmed

Grb2-Mediated Recruitment of USP9X to LAT Enhances Themis Stability following Thymic Selection.

USP9X GRB2

1.90e-05388228877990
Pubmed

Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice.

PTPRJ MATK

1.90e-05388232016283
Pubmed

Polypeptide chain release factor eRF3 is a novel molecular partner of survivin.

GSPT2 GSPT1

1.90e-05388223377885
Pubmed

Formin mDia1, a downstream molecule of FMNL1, regulates Profilin1 for actin assembly and spindle organization during mouse oocyte meiosis.

DIAPH1 FMNL1

1.90e-05388225447542
Pubmed

Mechanistic differences in actin bundling activity of two mammalian formins, FRL1 and mDia2.

DIAPH1 FMNL1

1.90e-05388216556604
Pubmed

The processed isoform of the translation termination factor eRF3 localizes to the nucleus to interact with the ARF tumor suppressor.

GSPT2 GSPT1

1.90e-05388224569073
Pubmed

Bi-modal regulation of a formin by srGAP2.

FMNL3 FMNL1

1.90e-05388221148482
Pubmed

The filamentous actin cross-linking/bundling activity of mammalian formins.

DIAPH1 FMNL1

1.90e-05388218835565
Pubmed

FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42.

FMNL3 FMNL2

1.90e-05388228852060
Pubmed

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

ZNF131 PLOD3 ZFYVE9 ORC6 BANP DEF6 ALKBH3 GRB2 HOOK2 TRAF3IP3 BRMS1L ZNF302 CCDC102B UBASH3A

1.98e-051477881431515488
Pubmed

An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis.

PTPRJ GRB2

3.79e-05488219836242
Pubmed

Structural insights into eRF3 and stop codon recognition by eRF1.

GSPT2 GSPT1

3.79e-05488219417105
Pubmed

Resistance to noise-induced hearing loss in 129S6 and MOLF mice: identification of independent, overlapping, and interacting chromosomal regions.

DIAPH1 POU4F3 ATP8B1

5.45e-052988324952082
Pubmed

Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase.

GSPT2 GSPT1

6.30e-05588214685257
Pubmed

CCDC102B functions in centrosome linker assembly and centrosome cohesion.

CEP250 CCDC102B

6.30e-05588230404835
Pubmed

Mutant p53 protects ETS2 from non-canonical COP1/DET1 dependent degradation.

PTPRJ COP1

6.30e-05588226871468
Pubmed

The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.

GSPT2 GSPT1

9.43e-05688210358005
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

MSH6 DSP ORC6 INTS13 DIAPH1 FIP1L1 PLRG1 GSPT1

1.16e-0458288820467437
Pubmed

Functional proteomics mapping of a human signaling pathway.

ZNF675 FMNL3 ZMYND11 ZFYVE9 CEP250 DIAPH1 FMNL2 FMNL1

1.29e-0459188815231748
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

JADE3 BRMS1L TRRAP

1.67e-044288316387653
Pubmed

3D-structured illumination microscopy provides novel insight into architecture of human centrosomes.

CEP250 CNTRL

1.75e-04888223213374
Pubmed

GRB2 enforces homology-directed repair initiation by MRE11.

GRB2 POLQ

1.75e-04888234348893
Pubmed

Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways.

PLOD3 ALOX12

1.75e-04888219713213
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

PTPRN2 ORC6 ZNF665 INTS13 USP9X DNAH2 MRPS27 CCDC102B

2.18e-0463888831182584
Pubmed

Mammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencing.

GSPT2 GSPT1

2.25e-04988221726813
Pubmed

Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1.

COP1 CACYBP

2.25e-04988221297076
Pubmed

A human MAP kinase interactome.

MAP1A DSP CEP250 CNTRL GRB2 MAPKAPK5 FMNL2

2.39e-0448688720936779
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

MSH6 PLOD3 DSP TRRAP PHIP

2.42e-0421988531353912
Pubmed

Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.

DSP MATK CEP250 ZNF726

2.51e-0412088421697133
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF665 ZNF850 ZNF726

2.65e-04498839630514
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

PLOD3 USP9X MRPS27 GRB2 USP9Y TRRAP PLRG1

2.73e-0449788736774506
Pubmed

Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.

USP9X USP9Y

2.81e-04108829384609
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NDST1 DMXL2 DSP USP9X MCF2L2 FIP1L1 ZNF302 USP9Y UBASH3A FMNL2 LRP1B

3.97e-041285881135914814
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

MSH6 DMXL2 MAP1A DSP MRPS27 FIP1L1 PPIP5K2 USP9Y TRRAP PLRG1

4.09e-041082881038697112
Pubmed

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.

ABCA1 PTPRJ

4.11e-041288225173106
Pubmed

Systematic Identification of Oncogenic EGFR Interaction Partners.

DIAPH1 CNKSR2

4.11e-041288227956147
Pubmed

Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis.

USP9X USP9Y

4.11e-041288223861879
Pubmed

MRG15 is a novel PALB2-interacting factor involved in homologous recombination.

MSH6 TRRAP

4.11e-041288219553677
Pubmed

An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.

KBTBD6 COP1 PHIP

4.59e-045988319295130
Pubmed

Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon.

PTPRJ DSP

4.85e-041388220139419
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MSH6 PUS3 PTPRN2 ORC6 USP9X GRB2 COP1 CHCHD1 MAPKAPK5 TRRAP ALOX12

5.20e-041327881132694731
Pubmed

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.

GSPT2 GSPT1

5.65e-041488216452507
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DMXL2 GSPT2 MAP1A DSP USP9X MRPS27 CNKSR2 GRIN1 CACYBP LRP1B

6.10e-041139881036417873
Pubmed

Deubiquitinating enzymes: a new class of biological regulators.

USP9X USP9Y

6.51e-04158829827704
Pubmed

Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains.

MATK GRB2

6.51e-041588210679268
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

USP9X USP9Y

6.51e-041588214762062
Pubmed

Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice.

ABCA1 GRIN1

7.42e-041688226263173
Pubmed

The embryonic expression pattern of 40 murine cDNAs homologous to Drosophila mutant genes (Dres): a comparative and topographic approach to predict gene function.

USP9X DIAPH1

7.42e-04168829817915
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

DMXL2 MAP1A USP9X CNKSR2 GRIN1

7.53e-0428188528706196
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

MSH6 NDST1 GSPT2 CEP250 CNTRL

8.03e-0428588532838362
Pubmed

A strategy for modulation of enzymes in the ubiquitin system.

USP9X USP9Y

8.40e-041788223287719
Pubmed

The functional interactome landscape of the human histone deacetylase family.

MSH6 USP9X FIP1L1 BRMS1L PHIP

8.54e-0428988523752268
Pubmed

Network organization of the human autophagy system.

PLOD3 MAP1A KBTBD6 BANP CACYBP GSPT1

8.65e-0443788620562859
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

MSH6 PLOD3 GSPT2 DSP USP9X DIAPH1 MRPS27 GRB2 CACYBP PLRG1 GSPT1

8.81e-041415881128515276
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

MSH6 PLOD3 USP9X FIP1L1 CACYBP TRRAP

8.96e-0444088634244565
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

USP9X USP9Y

9.43e-041888212023983
Pubmed

Elevation of hsa-miR-7-5p level mediated by CtBP1-p300-AP1 complex targets ATXN1 to trigger NF-κB-dependent inflammation response.

KCTD19 DIAPH1 OSBPL9 PLRG1

9.54e-0417188436629882
Pubmed

Human transcription factor protein interaction networks.

ZNF131 KBTBD6 USP9X BANP MRPS27 COP1 FIP1L1 BRMS1L CACYBP TRRAP ZNF850

9.55e-041429881135140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ZNF675 GSPT2 DSP CNTRL CEP83 DNAH2 PPIP5K2 METTL25 POLQ DNAJB14 GSPT1

1.03e-031442881135575683
Pubmed

Localization of ubiquitin gene family members to mouse chromosomes 5, 11, and 18.

TPST2 POU4F3

1.17e-03208829321482
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF850 ZNF726

1.17e-03208827479878
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF850 ZNF726

1.17e-03208822542606
Pubmed

Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.

ZNF10 ZNF302

1.29e-03218827865130
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MSH6 PLOD3 ZFYVE9 PTPRJ PTPRN2 DSP USP9X GRB2 CACYBP

1.35e-03104988927880917
Pubmed

Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling.

USP9X GRB2

1.41e-032288226811477
Pubmed

The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.

FMNL3 MSH6 MAP1A USP9X OSBPL9

1.44e-0332588536168628
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

KANSL1L DMXL2 DSP HOOK2 BRMS1L ZNF302

1.67e-0349788623414517
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

MSH6 DMXL2 USP9X MRPS27 PPIP5K2 PHIP

1.68e-0349888636634849
Pubmed

PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation.

PUS3 CACYBP

1.68e-032488224710276
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ZNF131 MSH6 ORC6 GRB2 FIP1L1 CACYBP TRRAP PLRG1 GSPT1

1.91e-03110388934189442
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

MSH6 MAP1A KBTBD6 USP9X MRPS27 GRB2 FIP1L1 CACYBP TRRAP PLRG1

2.01e-031335881029229926
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DMXL2 MCF2L2 CNKSR2

2.12e-0310088310048485
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

CEP250 BRMS1L PLRG1

2.18e-0310188326949739
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

MCF2L2 GRB2 FIP1L1 CNKSR2 CACYBP PPIP5K2 PLRG1 GSPT1

2.26e-0391688832203420
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

PTPRJ DIAPH1 GRB2

2.31e-0310388321706016
Pubmed

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.

JADE3 ALKBH3 ZNF302 FMNL1 GLP2R

2.35e-0336488531391242
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF718 ZNF726

2.46e-032988214563677
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

MSH6 TRAF3IP3 PLRG1 FMNL1 GSPT1

2.52e-0337088522922362
InteractionDAAM2 interactions

FMNL3 PDE6B DIAPH1 FMNL2 FMNL1

5.99e-0738875int:DAAM2
InteractionDIAPH1 interactions

FMNL3 PDE6B DIAPH1 MRPS27 GRB2 FMNL2 PHIP FMNL1

9.37e-07176878int:DIAPH1
InteractionKIAA0408 interactions

MAP1A GRB2 HOOK2 USP9Y UBASH3A

6.57e-0661875int:KIAA0408
InteractionPDE6B interactions

PDE6B DIAPH1 FMNL2 FMNL1

7.09e-0629874int:PDE6B
InteractionPRPF18 interactions

FMNL3 DIAPH1 HOOK2 CCDC102B FMNL2 FMNL1

1.34e-05120876int:PRPF18
InteractionDAAM1 interactions

FMNL3 PDE6B DIAPH1 FMNL2 FMNL1

1.49e-0572875int:DAAM1
InteractionDCAF6 interactions

FMNL3 KCTD19 DSP USP9X GRB2 GRIN1 PHIP

4.82e-05221877int:DCAF6
InteractionFGFR1OP2 interactions

GANC BANP CEP83 TRAF3IP3 UBASH3A

5.42e-0594875int:FGFR1OP2
InteractionFMNL3 interactions

FMNL3 DIAPH1 FMNL2 FMNL1

5.92e-0549874int:FMNL3
InteractionAHNAK interactions

ZNF131 PLOD3 JADE3 DSP GRB2 CACYBP PPIP5K2 FMNL1

6.97e-05318878int:AHNAK
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF675 ZNF10 ZNF131 ZNF718 ZNF665 ZNF302 ZNF850 ZNF726

1.76e-0371857828
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRJ PTPRN2

1.97e-0321572813
GeneFamilyPWWP domain containing

MSH6 ZMYND11

2.17e-03225721147
ToppCellControl-Lymphocytic_NKT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

1.83e-0618588659d68e119f58b35bab36294758f6b2e25fd8f5c0
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPST2 MATK DEF6 TRAF3IP3 UBASH3A FMNL1

2.00e-06188886a2f42a86418a52cd12c3a699ab290d7d86826359
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MATK IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

2.40e-0619488669f7bedf6f0be338e4317c22125e727fb82000fc
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

DMXL2 ABCA1 PTPRJ GRB2 FMNL2 FMNL1

2.48e-06195886148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

DMXL2 ABCA1 HLA-DPB1 MCF2L2 GRB2 FMNL2

2.48e-0619588646ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DMXL2 ABCA1 PTPRJ GRB2 FMNL2 FMNL1

2.55e-061968867026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellFetal_29-31_weeks-Immune-monocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DMXL2 PTPRJ HLA-DPB1 ASGR2 GRB2 FMNL1

2.63e-0619788648a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCellFetal_29-31_weeks-Immune-monocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DMXL2 PTPRJ HLA-DPB1 ASGR2 GRB2 FMNL1

2.63e-061978868b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCellLPS_IL1RA-Hematopoietic_Lymphocytic-Lymphocytic_NK/T|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MATK IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

2.70e-06198886a07590c6aa2c889b5d1a0413a6fba5b75bf5d70a
ToppCellLPS_IL1RA_TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MATK IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

2.70e-0619888622c412a8d370fabfe4ccfad0b4c24fc965b88b74
ToppCellLPS_IL1RA_TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MATK IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

2.78e-06199886c23a53a20487a8abfeb91fa5fc9c06823dd657e9
ToppCellLPS_IL1RA-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MATK IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

2.78e-061998860c743e4e88cbd2ca72e5161ca22a3e974b26f9b4
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7|TCGA-Brain / Sample_Type by Project: Shred V9

PI4K2B FIP1L1 POLQ ZNF850 ZNF726

7.51e-06136885d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCellCV-Mild-4|Mild / Virus stimulation, Condition and Cluster

ZFYVE9 CNKSR2 USP9Y POLQ UBASH3A

1.65e-051608852e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF718 MATK UBASH3A FMNL2 ZNF850

2.21e-05170885a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF718 MATK UBASH3A FMNL2 ZNF850

2.21e-05170885b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A JADE3 ZNF665 BANP ZNF726

2.21e-05170885db0ec8b7ecbb4db108fc35c564df4b740f65cc8f
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A JADE3 ZNF665 BANP ZNF726

2.21e-0517088588f6804e973863245ca1c7e5e6656d4a8b824da9
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A JADE3 ZNF665 BANP ZNF726

2.21e-05170885dad3aaf7d9f7bafdbddee51610f03f2359e587ae
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK IL21R DEF6 TRAF3IP3 UBASH3A

2.68e-05177885f1efd9c3074d5635700fe7fbebf3dd0b1e0a84f1
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK IL21R DEF6 TRAF3IP3 UBASH3A

2.75e-051788857905621f5b2aa55324c5592d1d2fef763a5fa41f
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK IL21R DEF6 TRAF3IP3 UBASH3A

2.75e-05178885f914092c20130207193f97c6044ae61a9a440a86
ToppCellControl-Lymphocytic_NKT-T_cells-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

2.75e-05178885910f8bea19d335455aba24e6a07b4834b709db5d
ToppCellLPS-antiTNF-Lymphocytic_NKT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK IL21R DEF6 TRAF3IP3 UBASH3A

2.83e-05179885ecea75c568911ff56939c9f67ab901497bd4356c
ToppCellLPS-IL1RA-Lymphocytic_NKT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK IL21R DEF6 TRAF3IP3 UBASH3A

2.83e-051798855ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCellControl-Lymphocytic_NKT-T_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

2.83e-05179885d892d9496f1c33e23312092591eb2e968e736f7d
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MATK IL21R TRAF3IP3 UBASH3A FMNL1

2.90e-05180885702673c0b7c5b0d22a6af3884374804b8c4d6254
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

3.06e-051828857dd435e456da1470d19d3db307ae4909c25d2f0d
ToppCell15-Distal-Immune-Hematopoietic,_T_Cells|Distal / Age, Tissue, Lineage and Cell class

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

3.31e-05185885481e3d3b63f2e5b4783088523c3cf70a461aed27
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPB1 ASGR2 IL21R DEF6 FMNL1

3.40e-05186885bec4767eaca28e41da373274704895eba75063e2
ToppCellLPS_only-Lymphocytic_NKT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK IL21R DEF6 TRAF3IP3 UBASH3A

3.57e-05188885bbe65b1c11c88ab62d8485cfc3a913ff9da89aad
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPB1 ASGR2 IL21R DEF6 FMNL1

3.57e-05188885239bec13476dd43bebc2c6eba8d1fe35f2744673
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HLA-DPB1 ASGR2 DIAPH1 GRB2 FMNL1

3.76e-05190885ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD19 ORC6 IL21R POLQ FMNL1

3.76e-05190885b65383e256b04122500b742caeed0b807793851e
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD19 ORC6 IL21R POLQ FMNL1

3.76e-0519088589095d3e023269d89c82e3a73550f869e3f34201
ToppCell3'_v3-blood-Lymphocytic_T_CD8-Tem/emra_CD8|blood / Manually curated celltypes from each tissue

TPST2 HLA-DPB1 MATK TRAF3IP3 USP9Y

3.76e-051908855624f711b34132081f93fa70702316962e3e3c64
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

3.85e-051918851fde5b0cd2b85d4a4a6c71da8316ecd2fde676fa
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

FMNL3 PTPRJ HLA-DPB1 IL21R GRB2

3.85e-05191885cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MATK IL21R DEF6 TRAF3IP3 UBASH3A

3.95e-0519288592f141d5ac462f652f405efa73ac6ef751f40ea3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MATK IL21R TRAF3IP3 UBASH3A FMNL1

3.95e-05192885b498618505bb1b7ff9574d06875dd272c11bac39
ToppCell18-Distal-Immune-Hematopoietic,_T_Cells|Distal / Age, Tissue, Lineage and Cell class

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

3.95e-051928857538c7f63108f357478ea4c5bf27c1f9825b87c7
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D175|Adult / Lineage, Cell type, age group and donor

FMNL3 DMXL2 ABCA1 PTPRJ GRB2

3.95e-05192885733491e932350e3c216a626cc49c3cd3fe970a82
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA1 PTPRJ MCF2L2 COP1 FMNL2

4.05e-05193885779276e775cb2492e8dd36436295a536084a6415
ToppCell15-Airway-Immune-Hematopoietic,_T_Cells|Airway / Age, Tissue, Lineage and Cell class

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.25e-05195885ec392fc8bd2c0f1e3a79f2e401608fd6ba8d339c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DPB1 CNTRL DEF6 TRAF3IP3 FMNL1

4.25e-051958857b6c69df943842b566a596e30bb50dbe80dccc83
ToppCellwk_15-18-Hematologic_Lymphocytic-NK-CD16+_NK|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TPST2 MATK DEF6 TRAF3IP3 FMNL1

4.25e-05195885eadc2f8dd16d2b76c59b85f72905bd4b1545b560
ToppCellCOVID-19-lung-Macrophage_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

DMXL2 ABCA1 PTPRJ GRB2 FMNL2

4.36e-05196885a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-TRDV2/TRGV9_gdT|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.36e-051968858e20ffe39157619b1d02b48d2cf9d62f26bdb3e8
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MATK IL21R TRAF3IP3 UBASH3A FMNL1

4.36e-05196885ab6022041c33617bca3ed0c62f19673cd2750da9
ToppCell18-Airway-Immune-Hematopoietic,_T_Cells|Airway / Age, Tissue, Lineage and Cell class

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.46e-05197885ba40a8b6871c8a0166195c03e7e3deae5834ec56
ToppCellCOVID-19-kidney-Macrophages|COVID-19 / Disease (COVID-19 only), tissue and cell type

DMXL2 ABCA1 PTPRJ HLA-DPB1 GRB2

4.46e-051978853912301018d0863144dcfac8d1fa8adc081748d7
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

DMXL2 PTPRJ ASGR2 GRB2 FMNL1

4.46e-05197885a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

DMXL2 PTPRJ GRB2 FMNL2 FMNL1

4.46e-051978853896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.46e-05197885dfec2afd1cbe218c9234ce7d4b5a5839b268398d
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF10 MATK DEF6 TRAF3IP3 UBASH3A

4.57e-051988850dac00a64fe08ec6669af3ddd4b82413b673233d
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D231|Adult / Lineage, Cell type, age group and donor

DMXL2 ABCA1 HLA-DPB1 MCF2L2 GRB2

4.57e-0519888579a415e19cedde13a88f5043d71557363f102322
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DMXL2 PTPRJ ASGR2 GRB2 FMNL1

4.57e-05198885ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellTransverse-T_cell-cycling_gd_T|Transverse / Region, Cell class and subclass

ORC6 CCDC34 MATK POLQ ZNF850

4.57e-051988855131b0b7d6c4dd8872cef9f2e233f59f751b4690
ToppCellCOVID-19-Myeloid|COVID-19 / group, cell type (main and fine annotations)

DMXL2 ABCA1 HLA-DPB1 GRB2 FMNL2

4.57e-0519888533f0a919188a67d2a876b52c61a1cec2c9747969
ToppCellFetal_29-31_weeks-Immune|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HLA-DPB1 DEF6 GRB2 TRAF3IP3 FMNL1

4.57e-051988855dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCellLPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T|LPS_only / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.57e-05198885584dbfeb0bb0358d3757aee56184e91ba35247ae
ToppCellLPS_only-Hematopoietic_Lymphocytic|LPS_only / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.57e-05198885e4e362dca57adba90a2be38dce810857baa2f265
ToppCellControl_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T|Control_saline / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.57e-051988859663cf0c8296d3a7b0329cb725ccceeea7849cbc
ToppCellTransverse-(1)_T_cell-(18)_cycling_gd_T|Transverse / shred on region, Cell_type, and subtype

ORC6 CCDC34 MATK POLQ ZNF850

4.57e-05198885396dddf7ebad41c3a91329b6a280623c0dfdcd2f
ToppCellCOVID-19-kidney-Macrophages|kidney / Disease (COVID-19 only), tissue and cell type

DMXL2 ABCA1 HLA-DPB1 GRB2 FMNL1

4.57e-05198885161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCell18-Distal-Immune|Distal / Age, Tissue, Lineage and Cell class

HLA-DPB1 MATK DEF6 TRAF3IP3 FMNL1

4.57e-05198885e68d4a152f0d19fe161c75a0cb844f505b667b6b
ToppCellImmune-monocyte|World / Lineage, Cell type, age group and donor

DMXL2 PTPRJ ASGR2 GRB2 FMNL1

4.57e-05198885d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCellControl_saline-Hematopoietic_Lymphocytic|Control_saline / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.57e-05198885d442b35768fe0f75a971784af23400d5d0c7530a
ToppCellLPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|LPS_only / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.68e-05199885b62a756b5472972156d05051a58671a58bef1f16
ToppCellControl_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|Control_saline / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.68e-051998852d7ebb9642f6fe0afd5e3fdc711ded54b73acd11
ToppCellcellseq2-Immune|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MATK DEF6 GRB2 TRAF3IP3 FMNL1

4.68e-05199885631f29931d102ea308088809a05281588c9c9e3d
ToppCell15-Trachea-Immune-Hematopoietic,_T_Cells|Trachea / Age, Tissue, Lineage and Cell class

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.68e-05199885d5dcf7b4f58a075a7f729165556f7666e6b4c104
ToppCellLPS_IL1RA_TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-T-cells|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

IL21R DEF6 TRAF3IP3 UBASH3A FMNL1

4.68e-0519988546e2d2962cd5b0f76baf976c0f6ecce117827274
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMXL2 ABCA1 HLA-DPB1 GRB2 FMNL1

4.68e-051998855ceeed92f831d068ff4bb3994f420002338330e7
ToppCell5'-GW_trimst-2-LymphNode|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF10 MATK DEF6 TRAF3IP3 UBASH3A

4.68e-051998854a9ca133125dc25a06e7b1cfea15ecffa449c20e
ToppCellLPS_IL1RA-Hematopoietic_Lymphocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.68e-05199885b6a700e101e0418be3ed51ce72a49596bb32d199
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF10 MATK DEF6 TRAF3IP3 UBASH3A

4.68e-0519988545d0d275ffb4183e3e71f4701e121ef9853ebd10
ToppCellLPS_IL1RA_TNF-Hematopoietic_Lymphocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.68e-051998855611b9e405a685a7a099d2f2d21dee3a939c2911
ToppCell356C-Lymphocytic-NK_cells-Proliferating_NK_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

MSH6 ORC6 CCDC34 MATK POLQ

4.68e-05199885e3b69608c834bd8ce6bedde298a2763cc0d7d573
ToppCellLPS_anti-TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.68e-05199885f44f53a55c8acd4d4769df925c749393b8ecadb7
ToppCellLPS_anti-TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MATK DEF6 TRAF3IP3 UBASH3A FMNL1

4.68e-051998850986d4342dc61e623d0dfc9f9870af86f72a8be3
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 PTPRJ GRB2 TRAF3IP3 FMNL1

4.68e-05199885ac866ae110967c5867ff4601939b79861d43df54
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF10 MATK DEF6 TRAF3IP3 UBASH3A

4.68e-05199885da20998253ad08a4a127a98b991b26237edb61a2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PI4K2B TPST2 DNAH2 CCDC102B ITIH5

4.79e-05200885aafe594c88710f8c53d59667cdac5035e08f5511
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRJ PTPRN2 ATP8B1 HOOK2 GALNT7

4.79e-05200885d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8_CTL|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MATK IL21R DEF6 TRAF3IP3 UBASH3A

4.79e-05200885dc719c7f0ffee0db4f56f1991e47974dc7bef11b
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 PTPRJ ASGR2 GRB2 FMNL1

4.79e-052008855432bdf495431cd26f6e4cd585100f3652588913
ToppCellSigmoid-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

DMXL2 ORC6 CCDC34 POLQ FMNL2

4.79e-05200885372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCell11.5-Distal-Immune|Distal / Age, Tissue, Lineage and Cell class

ASGR2 MATK DEF6 TRAF3IP3 FMNL1

4.79e-05200885c9ed06ae7a8f5a88578c8269d762d8739ae79c7f
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 PTPRJ ASGR2 GRB2 FMNL1

4.79e-052008858872d5fa101d413fb43b4231d476878678543035
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PI4K2B TPST2 DNAH2 CCDC102B ITIH5

4.79e-05200885a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCell15-Distal-Immune|Distal / Age, Tissue, Lineage and Cell class

HLA-DPB1 MATK DEF6 TRAF3IP3 FMNL1

4.79e-05200885b7083124869791280a2235f484f3659a91dd3600
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK IL21R DEF6 UBASH3A

1.45e-0413488492981dc68c1b3cdc53f9cf83386c47f0c6c98ae7
ToppCellTuft-tuft-3|World / Class top

NDST1 JADE3 ASGR2 MAPKAPK5

2.12e-04148884f4f59b46a79fc9aa4c5d330a7b37b1a34a6d71cc
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IL21R TRAF3IP3 ALOX12 FMNL1

2.17e-0414988443d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IL21R TRAF3IP3 ALOX12 FMNL1

2.17e-041498841c5a2572741c47246d455c865e8e1677c9f49598
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK DEF6 TRAF3IP3 UBASH3A

2.28e-04151884b85a763459a0f019d1f9975d09b9f2247d62c9d3
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL21R TRAF3IP3 UBASH3A FMNL1

2.59e-0415688439aa3adbee9f04cdc0055487d393edfa515e062b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL21R TRAF3IP3 UBASH3A FMNL1

2.59e-04156884a09e3aefe78d63ad5428ad48c6f83e547eb819f6
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATK DEF6 ALKBH3 FMNL1

2.65e-04157884d8e283414a770f05d71f0455d0822e9a9660b115
DiseaseAdenocarcinoma of large intestine

MSH6 MATK NRK TRRAP

1.82e-0496864C1319315
DiseaseIntellectual Disability

NDST1 ZMYND11 PUS3 DIAPH1 GRIN1 TRRAP PHIP

3.35e-04447867C3714756
DiseaseRS-warfarin measurement

BANP MCF2L2 LRP1B PHIP

5.45e-04128864EFO_0803325
DiseaseColorectal Carcinoma

MSH6 ABCA1 PTPRN2 INTS13 MCF2L2 CNKSR2 TRAF3IP3 PHIP

1.02e-03702868C0009402
Diseaseaspartate aminotransferase measurement

ABCA1 PTPRJ HLA-DPB1 DEF6 DNAH2 GRB2 ATP8B1 SERPINA2 PHIP

1.28e-03904869EFO_0004736
Diseaseuridine diphosphate measurement

ZMYND11 PTCHD3

1.54e-0320862EFO_0010545
DiseaseAntiglaucoma preparations and miotics use measurement

ABCA1 PTPRJ

2.61e-0326862EFO_0009944
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

MSH6 PTPRJ

2.61e-0326862C0009405
DiseaseHereditary non-polyposis colorectal cancer syndrome

MSH6 PTPRJ

2.81e-0327862C1112155
Diseaseretinitis pigmentosa (implicated_via_orthology)

PDE6B CEP250

2.81e-0327862DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ESDWYRIKQSIDSKC

BANP

301

Q8N9N5
SKVYQEHEKRCWSVD

COP1

506

Q8NHY2
QTDWCYDRTAVKSLK

ERICH6B

276

Q5W0A0
KDISEWANRFEDCQK

CNTRL

1906

Q7Z7A1
WANRFEDCQKEEETK

CNTRL

1911

Q7Z7A1
KAWAEAEKYCQLENA

ASGR2

196

P07307
DNVERTNKIKDGYWD

ABCA1

561

O95477
LLCNLYRNEKDSVDW

ALKBH3

176

Q96Q83
EYWNSQKDILEEKRA

HLA-DPB1

86

P04440
DVWRQSEKDQYEEKL

CEP83

416

Q9Y592
ECNKSDEKEIYHWKR

DMXL2

1036

Q8TDJ6
CFWTKVKEDRFENNE

DIAPH1

796

O60610
ECTWQVKANDRKYHE

ATP8B1

61

O43520
SKNLWEQICKEYEAE

IQCK

51

Q8N0W5
YEQEKSWQDSERLKG

INTS13

591

Q9NVM9
AQCEAYKSWTQEKES

KCTD19

486

Q17RG1
NKNRLEKEWEALCAY

PTPRN2

741

Q92932
KLEDQNEYESRSLWK

OSBPL9

656

Q96SU4
IHQIVRQWKYKDDDD

PLOD3

176

O60568
RTKCEEYWPSKQAQD

PTPRJ

1146

Q12913
CKWYQENALLDKVTD

KANSL1L

171

A0AUZ9
ENKLYWCDARTDKIE

LRP1B

2051

Q9NZR2
LEQDTYWRELSCERK

MAP1A

1691

P78559
TILEACENKSWYRVK

MATK

76

P42679
EAWKYNRECKLLRDT

MAPKAPK5

421

Q8IW41
KQRKIYNGEEQIDCW

ITIH5

891

Q86UX2
WLFECRNLEEKYESV

HOOK2

386

Q96ED9
RLCYLKEQEDIAWSA

METTL25

566

Q8N6Q8
KYILQAASKEIRDCW

MCF2L2

931

Q86YR7
VNWSIERYEECKEKL

GSPT2

356

Q8IYD1
EDKQVKCWDLEYNKV

PLRG1

266

O43660
QNNRKEWKALADEYE

PDE6B

801

P35913
TRWDYLTQVEKECKE

CACYBP

161

Q9HB71
NEDTWKAYCEKQKRI

FIP1L1

181

Q6UN15
HQCRWNYEDEQDVKA

GANC

366

Q8TET4
NLDAWNRELLDKYCV

NDST1

146

P52848
EKVRQCWQDDELFSY

ALOX12

216

P18054
DKNYKDWQSAVECIA

MSH6

1041

P52701
KVLNEECDQNWYKAE

GRB2

26

P62993
TVNWSNERYEECKEK

GSPT1

226

P15170
GNDNWLVRYEKQKCE

PI4K2B

306

Q8TCG2
DQGDWEDLACQKISY

SERPINA2

41

P20848
WKQNEFRDDACRKEI

CHCHD1

56

Q96BP2
WAQYKQACLRDLLKE

GLP2R

76

O95838
YQEWLKKKNAEECER

CCDC34

236

Q96HJ3
EEDYVTNIRNNCWKE

DNAJB14

321

Q8TBM8
ENAVCDDYITEKFWR

FUT10

281

Q6P4F1
DRSVNDLRQEECKYW

GALNT7

186

Q86SF2
RQYDNEKKWDLICDQ

FMNL3

56

Q8IVF7
EKKWDLICDQERFQV

FMNL3

61

Q8IVF7
WYLQSCLRKESDKEC

POLQ

1946

O75417
ECILKDNNERSKWYV

DSP

481

P15924
AKVLQYRSWCQELEK

CEP250

61

Q9BV73
DELCWTLTAKKNYRA

DEF6

91

Q9H4E7
DNEKKWELICDQERF

FMNL2

56

Q96PY5
LSQYDNEKKWELICD

FMNL1

56

O95466
EWYIRGQTICIDKKD

BRMS1L

266

Q5PSV4
LAARLNCAEYKNWVK

CXorf38

6

Q8TB03
WQDQYEELKDEATSC

IL21R

51

Q9HBE5
SQLRFYWEKDLDDCV

DNAH2

1741

Q9P225
YWEKDLDDCVIRQTN

DNAH2

1746

Q9P225
KGNEQIEKYSWREAC

DYNAP

6

Q8N1N2
SYNTNKWDICEELRL

CCDC102B

61

Q68D86
NRWVKNTEDLQCYVK

JADE3

721

Q92613
LKEVECYNVKRNQWA

KBTBD6

451

Q86V97
DYWDKDVRQKLENCT

PTCHD3

666

Q3KNS1
NQSLKEDWIAYICRE

NRK

146

Q7Z2Y5
TWIRQCLKYDAQDKA

MRPS27

111

Q92552
QLKRFDYDWERECAI

USP9X

1796

Q93008
DCKFENVKWIYDQEA

PUS3

326

Q9BZE2
DYEEWKRKILENAAS

ORC6

231

Q9Y5N6
WLEEAEAAYREKNSK

POU4F3

251

Q15319
RIKQEQDYWSESDKE

CNKSR2

676

Q8WXI2
VQKNTYDFECQWKDD

ZNF665

91

Q9H7R5
AEQKCEEWRSQYEAL

TRAF3IP3

311

Q9Y228
SYRDCLTKWNKAIEV

TPST2

206

O60704
EEWKCLDTSQQNLYR

ZNF718

16

Q3SXZ3
YDIQAWKKQCEELLN

PHIP

1316

Q8WWQ0
AIQLKRFDYDWEREC

USP9Y

1796

O00507
EEWQCLDTAQRNLYK

ZNF675

16

Q8TD23
LEEVWKCRDQLDKYQ

ZNF10

126

P21506
EEWQCLDTAQKNLYR

ZNF726

16

A6NNF4
QTKKKQWCYNCEEEA

ZMYND11

556

Q15326
EICNKRYLRESAWKQ

ZNF131

291

P52739
LRYGALCNESKDEQW

PPIP5K2

836

O43314
RCSKELNQWEALTEY

TRRAP

2826

Q9Y4A5
WECLDAAQKDLYRDV

ZNF850

21

A8MQ14
IKRNYSWDDQCSAVE

ZFYVE9

116

O95405
EKLQEFWRESKRQCA

UBASH3A

86

P57075
EEWACLDSAQRDLYK

ZNF302

16

Q9NR11
EDLDKTWVRYQECDS

GRIN1

786

Q05586