Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytokine activity

BMP2 BMP4 BMP8B IL16 TIMP1 BMP8A CCL27 GDF2

4.42e-06250758GO:0005125
GeneOntologyMolecularFunctiongrowth factor activity

BMP2 BMP4 BMP8B TIMP1 BMP8A GDF2

4.76e-05173756GO:0008083
GeneOntologyMolecularFunctionheparin binding

CFH BMP4 THBS2 LRTM2 CFHR4

7.81e-04192755GO:0008201
GeneOntologyMolecularFunctionRoundabout binding

TGFB1I1 LRTM2

8.97e-0412752GO:0048495
GeneOntologyMolecularFunctioncomplement component C3b binding

CFH CFHR4

8.97e-0412752GO:0001851
GeneOntologyMolecularFunctionreceptor ligand activity

BMP2 BMP4 BMP8B IL16 TIMP1 BMP8A CCL27 GDF2

1.02e-03547758GO:0048018
GeneOntologyMolecularFunctionBMP receptor binding

BMP2 BMP4

1.06e-0313752GO:0070700
GeneOntologyMolecularFunctionco-receptor binding

BMP2 BMP4

1.06e-0313752GO:0039706
GeneOntologyMolecularFunctionsignaling receptor activator activity

BMP2 BMP4 BMP8B IL16 TIMP1 BMP8A CCL27 GDF2

1.10e-03554758GO:0030546
GeneOntologyBiologicalProcesscartilage development

CFH BMP2 BMP4 BMP8B TIMP1 BMP8A GDF2 SMAD1 CFHR4

3.03e-07243779GO:0051216
GeneOntologyBiologicalProcessconnective tissue development

CFH BMP2 BMP4 BMP8B TIMP1 BMP8A GDF2 SMAD1 CFHR4

5.23e-06343779GO:0061448
GeneOntologyBiologicalProcessBMP signaling pathway

RGMA BMP2 BMP4 BMP8B CHRDL1 GDF2 SMAD1

8.91e-06197777GO:0030509
GeneOntologyBiologicalProcesspositive regulation of cartilage development

BMP2 BMP4 GDF2 SMAD1

9.66e-0636774GO:0061036
GeneOntologyBiologicalProcessresponse to BMP

RGMA BMP2 BMP4 BMP8B CHRDL1 GDF2 SMAD1

1.57e-05215777GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

RGMA BMP2 BMP4 BMP8B CHRDL1 GDF2 SMAD1

1.57e-05215777GO:0071773
GeneOntologyBiologicalProcessresponse to dietary excess

CFH BMP8B BMP8A CFHR4

2.83e-0547774GO:0002021
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

TGFB1I1 RGMA BMP2 BMP4 BMP8B CHRDL1 BMP8A GDF2 SMAD1

4.11e-05445779GO:0141091
GeneOntologyBiologicalProcesskidney development

CFH BMP2 BMP4 WFS1 PLXND1 SMAD1 PLCE1 CFHR4

7.39e-05372778GO:0001822
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

TGFB1I1 RGMA BMP2 BMP4 BMP8B CHRDL1 BMP8A GDF2 SMAD1

7.61e-05482779GO:0007178
GeneOntologyBiologicalProcessrenal system development

CFH BMP2 BMP4 WFS1 PLXND1 SMAD1 PLCE1 CFHR4

9.55e-05386778GO:0072001
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

CALCOCO2 RGMA BMP2 BMP4 THBS2 ATF7IP2 DGKD LRTM2 PLXND1 INO80 GDF2 SLX4 CLDN1 SPAG5 PLCE1

1.37e-0413667715GO:0051130
GeneOntologyBiologicalProcessglomerulus development

CFH BMP4 PLCE1 CFHR4

1.98e-0477774GO:0032835
GeneOntologyBiologicalProcessactivation of membrane attack complex

CFH CFHR4

2.04e-046772GO:0001905
GeneOntologyBiologicalProcesscardiac jelly development

BMP2 BMP4

2.04e-046772GO:1905072
GeneOntologyBiologicalProcessregulation of cartilage development

BMP2 BMP4 GDF2 SMAD1

2.40e-0481774GO:0061035
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

TGFB1I1 BMP2 BMP8B BMP8A GDF2 CLDN1 SMAD1

2.59e-04336777GO:0071560
GeneOntologyBiologicalProcesscell fate commitment

TGFB1I1 BMP2 BMP4 EPOP CHRDL1 LOXL3 SMAD1

2.68e-04338777GO:0045165
GeneOntologyBiologicalProcessregulation of complement activation, alternative pathway

CFH CFHR4

2.85e-047772GO:0030451
GeneOntologyBiologicalProcesspositive regulation of odontoblast differentiation

BMP2 BMP4

2.85e-047772GO:1901331
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

TGFB1I1 BMP2 BMP8B BMP8A GDF2 CLDN1 SMAD1

2.93e-04343777GO:0071559
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

TGFB1I1 RGMA BMP2 BMP4 BMP8B MARS1 CHRDL1 BMP8A GDF2 CLDN1 SMAD1

3.04e-048507711GO:0071363
GeneOntologyBiologicalProcessheart induction

BMP2 BMP4

3.80e-048772GO:0003129
GeneOntologyBiologicalProcesspositive regulation of neuroepithelial cell differentiation

BMP2 BMP4

3.80e-048772GO:1902913
GeneOntologyBiologicalProcessinflammatory response to wounding

CFH TIMP1 CFHR4

3.84e-0438773GO:0090594
GeneOntologyBiologicalProcessresponse to growth factor

TGFB1I1 RGMA BMP2 BMP4 BMP8B MARS1 CHRDL1 BMP8A GDF2 CLDN1 SMAD1

4.19e-048837711GO:0070848
GeneOntologyBiologicalProcessskeletal system development

CFH BMP2 BMP4 BMP8B TIMP1 BMP8A GDF2 SMAD1 CFHR4

4.66e-04615779GO:0001501
GeneOntologyBiologicalProcessmonocyte aggregation

CFH CFHR4

4.87e-049772GO:0070487
GeneOntologyBiologicalProcesspositive regulation of bicellular tight junction assembly

GDF2 CLDN1

4.87e-049772GO:1903348
GeneOntologyBiologicalProcessregulation of heart morphogenesis

BMP2 BMP4

4.87e-049772GO:2000826
GeneOntologyBiologicalProcessimmune complex clearance

CFH CFHR4

4.87e-049772GO:0002434
GeneOntologyBiologicalProcessameloblast differentiation

BMP2 BMP4

4.87e-049772GO:0036305
GeneOntologyBiologicalProcessnephron development

CFH BMP2 BMP4 PLCE1 CFHR4

4.88e-04174775GO:0072006
GeneOntologyBiologicalProcessmuscle hypertrophy in response to stress

BMP2 BMP4 SMAD1

5.17e-0442773GO:0003299
GeneOntologyBiologicalProcesscardiac muscle hypertrophy in response to stress

BMP2 BMP4 SMAD1

5.17e-0442773GO:0014898
GeneOntologyBiologicalProcesspositive regulation of SMAD protein signal transduction

BMP2 BMP4 GDF2

5.54e-0443773GO:0060391
GeneOntologyBiologicalProcesscardiac muscle adaptation

BMP2 BMP4 SMAD1

5.54e-0443773GO:0014887
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

TGFB1I1 BMP2 BMP8B BMP8A GDF2 SMAD1

5.82e-04276776GO:0007179
GeneOntologyBiologicalProcessretinal pigment epithelium development

CFH CFHR4

6.07e-0410772GO:0003406
GeneOntologyBiologicalProcessregulation of odontoblast differentiation

BMP2 BMP4

7.40e-0411772GO:1901329
GeneOntologyBiologicalProcessSMAD protein signal transduction

BMP2 BMP4 GDF2 SMAD1

7.68e-04110774GO:0060395
HumanPhenoSideroblastic anemia

FANCB BRCA2 WFS1 SLX4

1.80e-0535244HP:0001924
MousePhenoabnormal primordial germ cell morphology

FANCB BMP4 BMP8B ZNF296 SLX4 SMAD1

6.61e-0933636MP:0008391
MousePhenodecreased primordial germ cell number

FANCB BMP4 BMP8B ZNF296 SMAD1

1.73e-0729635MP:0008392
MousePhenodelayed allantois development

BMP2 BMP8B SMAD1

8.67e-075633MP:0004558
MousePhenoabsent primordial germ cells

BMP4 BMP8B SMAD1

1.73e-066633MP:0008393
MousePhenowhite pupil

CFH CFHR4

2.00e-052632MP:0006242
MousePhenodecreased serum complement activity

CFH CFHR4

2.00e-052632MP:0012553
MousePhenoartery occlusion

CFH CFHR4

2.00e-052632MP:0006134
MousePhenodecreased complement C5 level

CFH CFHR4

2.00e-052632MP:0012609
MousePhenoabnormal complement C5 level

CFH CFHR4

2.00e-052632MP:0012608
MousePhenoabnormal hepatic portal vein thrombosis

CFH CFHR4

2.00e-052632MP:0031159
MousePhenoretina detachment

CFH BMP4 CFHR4

3.82e-0515633MP:0003099
MousePhenoincreased susceptilbility to retina ischemic injury

CFH CFHR4

5.98e-053632MP:0012049
MousePhenoepididymis epithelium degeneration

BMP8B BMP8A

5.98e-053632MP:0004934
MousePhenoabnormal kidney venous thrombosis

CFH CFHR4

5.98e-053632MP:0031161
MousePhenoseminiferous tubule degeneration

FANCB BMP4 BMP8B ZNF296 BMP8A

7.06e-0596635MP:0001154
MousePhenoabnormal response to retina ischemic injury

CFH CFHR4

1.19e-044632MP:0012048
MousePhenoincreased susceptibility to type III hypersensitivity reaction

CFH CFHR4

1.19e-044632MP:0005615
MousePhenodecreased circulating complement protein level

CFH CFHR4

1.19e-044632MP:0020216
MousePhenomesangial cell interposition

CFH CFHR4

1.19e-044632MP:0011512
MousePhenoabnormal brain thrombosis

CFH CFHR4

1.19e-044632MP:0031168
MousePhenoincreased creatine level

CFH CFHR4

1.19e-044632MP:0010061
MousePhenoabnormal allantois morphology

BMP4 BMP8B BRCA2 ALG6 SMAD1

1.47e-04112635MP:0001726
MousePhenoabnormal venous thrombosis

CFH CFHR4

1.98e-045632MP:0031158
MousePhenoabnormal lung thrombosis

CFH CFHR4

1.98e-045632MP:0031167
MousePhenoabnormal circulating complement protein level

CFH CFHR4

2.96e-046632MP:0010215
MousePhenoepididymis degeneration

BMP8B BMP8A

4.14e-047632MP:0004935
MousePhenoabnormal glomerular capillary thrombosis

CFH CFHR4

4.14e-047632MP:0011508
MousePhenobrain ischemia

CFH CFHR4

5.50e-048632MP:0006080
MousePhenoabnormal pupil morphology

CFH BMP4 SLX4 CFHR4

5.77e-0485634MP:0001317
MousePhenoenhanced coordination

GALNT14 DRD4 LRTM2

6.58e-0438633MP:0003858
MousePhenoabnormal complement protein level

CFH CFHR4

7.05e-049632MP:0011566
MousePhenoabnormal creatine level

CFH CFHR4

7.05e-049632MP:0010060
MousePhenoabnormal type III hypersensitivity reaction

CFH CFHR4

8.79e-0410632MP:0002533
MousePhenoabnormal kidney thrombosis

CFH CFHR4

8.79e-0410632MP:0011507
MousePhenoabnormal developmental patterning

BMP2 BMP4 EFL1 BMP8B ZFAT BRCA2 ARMC5 VPS41 SMAD1

1.06e-03577639MP:0002084
MousePhenoabnormal lateral plate mesoderm morphology

BMP4 VPS41

1.07e-0311632MP:0010117
MousePhenoabnormal retina blood vessel pattern

BMP4 GDF2

1.07e-0311632MP:0010098
MousePhenoabnormal gastrulation

BMP2 BMP4 EFL1 BMP8B ZFAT ARMC5 VPS41 SMAD1

1.16e-03469638MP:0001695
DomainTGFb_propeptide

BMP2 BMP4 BMP8B BMP8A GDF2

1.02e-0728785PF00688
DomainTGF-b_N

BMP2 BMP4 BMP8B BMP8A GDF2

1.02e-0728785IPR001111
DomainInhibin_asu

BMP2 BMP8B BMP8A GDF2

1.96e-0713784IPR002405
DomainTGF-beta-rel

BMP2 BMP4 BMP8B BMP8A GDF2

2.06e-0732785IPR015615
DomainTGFb_CS

BMP2 BMP4 BMP8B BMP8A GDF2

2.06e-0732785IPR017948
DomainTGFB

BMP2 BMP4 BMP8B BMP8A GDF2

4.38e-0737785SM00204
DomainTGF-b_C

BMP2 BMP4 BMP8B BMP8A GDF2

4.38e-0737785IPR001839
DomainTGF_BETA_2

BMP2 BMP4 BMP8B BMP8A GDF2

4.38e-0737785PS51362
DomainTGF_beta

BMP2 BMP4 BMP8B BMP8A GDF2

4.38e-0737785PF00019
DomainTGF_BETA_1

BMP2 BMP4 BMP8B BMP8A GDF2

4.38e-0737785PS00250
Domain-

BMP2 BMP4 BMP8B BMP8A GDF2

8.80e-06677852.10.90.10
DomainCystine-knot_cytokine

BMP2 BMP4 BMP8B BMP8A GDF2

8.80e-0667785IPR029034
DomainDUF3657

FAM135A FAM135B

1.72e-052782IPR022122
DomainDUF676

FAM135A FAM135B

1.72e-052782PF05057
DomainDUF3657

FAM135A FAM135B

1.72e-052782PF12394
DomainDUF676_lipase-like

FAM135A FAM135B

1.72e-052782IPR007751
DomainRICIN

GALNT14 CRYBG1 LY75

2.13e-0428783SM00458
DomainRICIN_B_LECTIN

GALNT14 CRYBG1 LY75

2.13e-0428783PS50231
DomainVWC

THBS2 CHRDL1 MUC5AC

2.13e-0428783PF00093
DomainRicin_B_lectin

GALNT14 CRYBG1 LY75

2.62e-0430783IPR000772
DomainVWFC_1

THBS2 CHRDL1 MUC5AC

4.53e-0436783PS01208
DomainVWC

THBS2 CHRDL1 MUC5AC

5.32e-0438783SM00214
DomainVWFC_2

THBS2 CHRDL1 MUC5AC

5.32e-0438783PS50184
DomainVWF_dom

THBS2 CHRDL1 MUC5AC

7.15e-0442783IPR001007
Domain-

GPCPD1 PLCE1

4.85e-03257823.20.20.190
DomainRicin_B_lectin

GALNT14 CRYBG1

4.85e-0325782PF00652
DomainPLC-like_Pdiesterase_TIM-brl

GPCPD1 PLCE1

4.85e-0325782IPR017946
PathwayKEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY

BMP2 BMP4 BMP8B BMP8A SMAD1

1.89e-0820615M47843
PathwayKEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST

BMP2 BMP4 BMP8B BMP8A

4.18e-0715614M47824
PathwayPID_BMP_PATHWAY

RGMA BMP2 BMP4 CHRDL1 SMAD1

9.66e-0742615M181
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

BMP2 BMP4 BMP8B THBS2 BMP8A SMAD1

1.83e-0686616M2642
PathwayREACTOME_SIGNALING_BY_BMP

BMP2 CHRDL1 GDF2 SMAD1

9.15e-0631614M1662
PathwayREACTOME_SIGNALING_BY_BMP

BMP2 CHRDL1 GDF2 SMAD1

9.15e-0631614MM14789
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

BMP2 TIMP1 CHRDL1 ARHGEF18 GDF2 SMAD1

1.15e-05118616MM15588
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

BMP2 TIMP1 CHRDL1 ARHGEF18 GDF2 SMAD1

6.68e-05161616M27871
PathwayKEGG_HEDGEHOG_SIGNALING_PATHWAY

BMP2 BMP4 BMP8B BMP8A

9.85e-0556614M1053
PathwayWP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE

BMP2 BMP4 SMAD1

1.66e-0425613M39665
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR

CFH CFHR4

2.73e-046612M47880
PathwayBIOCARTA_ALK_PATHWAY

BMP2 BMP4 SMAD1

5.39e-0437613M17400
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

BMP2 BMP4 LOXL3

6.31e-0439613MM14601
PathwayKEGG_MEDICUS_REFERENCE_BMP9_10_SIGNALING_PATHWAY

GDF2 SMAD1

6.50e-049612M47822
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

BMP2 BMP4 LOXL3

9.00e-0444613M26969
PathwayKEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY

BMP2 SMAD1

9.88e-0411612M47848
PathwayWP_HEART_DEVELOPMENT

BMP2 BMP4 SMAD1

1.03e-0346613MM15884
PathwayWP_HEART_DEVELOPMENT

BMP2 BMP4 SMAD1

1.09e-0347613M39610
PathwayWP_BONE_MORPHOGENIC_PROTEIN_SIGNALING_AND_REGULATION

BMP2 SMAD1

1.18e-0312612M39519
PathwayWP_BMP2WNT4FOXO1_PATHWAY_IN_PRIMARY_ENDOMETRIAL_STROMAL_CELL_DIFFERENTIATION

BMP2 SMAD1

1.39e-0313612M39378
Pubmed

TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.

BMP2 BMP4 BMP8B BMP8A GDF2 SMAD1

3.00e-095579615342483
Pubmed

Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis.

BMP2 BMP4 BMP8B BMP8A

3.08e-0997941460021
Pubmed

BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo.

BMP2 BMP4 BMP8B SMAD1

8.04e-091179415289457
Pubmed

Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A SMAD1

1.13e-0837939076678
Pubmed

Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse.

BMP2 BMP4 BMP8B

1.13e-08379311401407
Pubmed

Requirement of Bmp8b for the generation of primordial germ cells in the mouse.

BMP4 BMP8B BMP8A

1.13e-08379310894154
Pubmed

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).

BMP4 BMP8B BMP8A

1.13e-08379312925636
Pubmed

Bmp7 regulates germ cell proliferation in mouse fetal gonads.

BMP2 BMP4 BMP8B BMP8A

1.74e-081379418391523
Pubmed

Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor.

RGMA BMP2 BMP4

4.50e-08479315975920
Pubmed

Activation of BMP-Smad1/5/8 signaling promotes survival of retinal ganglion cells after damage in vivo.

BMP2 BMP4 SMAD1

4.50e-08479322701694
Pubmed

Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling.

BMP2 BMP4 CHRDL1 SMAD1

5.74e-081779417693602
Pubmed

Genetic evidence that SOST inhibits WNT signaling in the limb.

TGFB1I1 BMP2 BMP4 GDF2 SMAD1

6.05e-084579520359476
Pubmed

Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages.

RGMA BMP2 BMP4 SMAD1

9.31e-081979421187450
Pubmed

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness.

BMP4 GDF2 SMAD1

1.12e-07579318997172
Pubmed

Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4.

RGMA BMP2 BMP4

1.12e-07579317472960
Pubmed

Cooperation of BMP and IHH signaling in interdigital cell fate determination.

BMP2 BMP4 CHRDL1 SMAD1

1.43e-072179429771958
Pubmed

Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.

TGFB1I1 BMP2 BMP4 SLFN12L BRCA2 GDF2 SMAD1

1.67e-0717779722560297
Pubmed

Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade.

BMP2 BMP4 SMAD1

2.24e-07679315188429
Pubmed

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.

BMP2 BMP4 SMAD1

2.24e-07679316604073
Pubmed

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development.

BMP2 BMP8B BMP8A

2.24e-0767937605753
Pubmed

Development of bat flight: morphologic and molecular evolution of bat wing digits.

BMP2 BMP4 SMAD1

2.24e-07679316618938
Pubmed

Effect of BMPs and Wnt3a co-expression on the osteogenetic capacity of osteoblasts.

BMP2 BMP4 GDF2

2.24e-07679327633082
Pubmed

Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.

BMP2 BMP4 CHRDL1 SMAD1

2.53e-072479436916392
Pubmed

The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.

BMP2 BMP4 GDF2 SMAD1

3.55e-072679431311865
Pubmed

Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis.

BMP2 BMP4 SMAD1

3.92e-07779319116164
Pubmed

Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps.

BMP2 BMP4 HS3ST2 SMAD1

4.84e-072879417698011
Pubmed

BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

BMP2 BMP4 CHRDL1 SMAD1

4.84e-072879423103586
Pubmed

Deletion of Lrp4 increases the incidence of microphthalmia.

BMP2 BMP4 BMP8B BMP8A SMAD1

5.33e-076979530352686
Pubmed

BMPER regulates cardiomyocyte size and vessel density in vivo.

BMP2 BMP4 SMAD1

6.27e-07879323200275
Pubmed

Inactivation of Msx1 and Msx2 in neural crest reveals an unexpected role in suppressing heterotopic bone formation in the head.

BMP2 BMP4 SMAD1

9.38e-07979320398647
Pubmed

A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.

BMP2 BMP4 CHRDL1

9.38e-07979314660436
Pubmed

A signaling principle for the specification of the germ cell lineage in mice.

BMP4 BMP8B SMAD1

9.38e-07979319410550
Pubmed

Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2.

BMP2 BMP4 SMAD1

9.38e-07979323344708
Pubmed

The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis.

BMP2 BMP4 SMAD1

1.34e-061079317218603
Pubmed

Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis.

BMP2 BMP4 SMAD1

1.34e-061079320727875
Pubmed

Bone morphogenetic protein 6-induced interleukin-1β expression in macrophages requires PU.1/Smad1 interaction.

BMP2 BMP4 SMAD1

1.34e-061079321571370
Pubmed

Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance.

BMP2 BMP4 SMAD1

1.84e-061179317847004
Pubmed

BMP signaling is required for normal thymus development.

BMP2 BMP4 SMAD1

1.84e-061179316210626
Pubmed

Hoxa2 Inhibits Bone Morphogenetic Protein Signaling during Osteogenic Differentiation of the Palatal Mesenchyme.

BMP2 BMP4 SMAD1

2.45e-061279329184513
Pubmed

Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice.

BMP2 BMP4 SMAD1

2.45e-061279323891934
Pubmed

Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal.

BMP2 BMP4 SMAD1

2.45e-061279319661464
Pubmed

BMPs are direct triggers of interdigital programmed cell death.

BMP2 BMP4 SMAD1

2.45e-061279326826495
Pubmed

The expression and crucial roles of BMP signaling in development of smooth muscle progenitor cells in the mouse embryonic gut.

BMP2 BMP4 SMAD1

3.17e-061379319272526
Pubmed

Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse.

BMP2 BMP4 SMAD1

3.17e-061379318329379
Pubmed

Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade.

BMP2 BMP4 SMAD1

3.17e-061379320130285
Pubmed

Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development.

BMP2 BMP4 SMAD1

4.03e-061479317693062
Pubmed

Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture.

BMP2 BMP4 SMAD1

4.03e-061479333248111
Pubmed

Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice.

BMP2 BMP4 SMAD1

4.03e-061479330413887
Pubmed

The short stature homeobox 2 (Shox2)-bone morphogenetic protein (BMP) pathway regulates dorsal mesenchymal protrusion development and its temporary function as a pacemaker during cardiogenesis.

BMP2 BMP4 SMAD1

4.03e-061479325488669
Pubmed

Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in mice.

BMP2 BMP4 SMAD1

4.03e-061479318483623
Pubmed

New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.

BMP4 BMP8B BMP8A

4.03e-061479311526197
Pubmed

Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation.

BMP2 BMP4 SMAD1

4.03e-061479312421925
Pubmed

Expression of the BMP receptor Alk3 in the second heart field is essential for development of the dorsal mesenchymal protrusion and atrioventricular septation.

BMP2 BMP4 SMAD1

4.03e-061479323584254
Pubmed

BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning.

BMP2 BMP4 SMAD1

4.03e-061479320508035
Pubmed

Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death.

BMP2 BMP4 SMAD1

5.03e-061579322240098
Pubmed

Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms.

BMP2 BMP4 SMAD1

5.03e-061579330235284
Pubmed

Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2).

BMP2 BMP4 SMAD1

5.03e-061579322547067
Pubmed

Absence of complement factor H reduces physical performance in C57BL6 mice.

CFH CFHR4

5.09e-06279232962822
Pubmed

Phenotype characterization and sequence analysis of BMP2 and BMP4 variants in two Mexican families with oligodontia.

BMP2 BMP4

5.09e-06279223079991
Pubmed

Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings.

CFH CFHR4

5.09e-06279220538999
Pubmed

Inheritance, hormonal regulation and properties of polymorphic murine antigens Mud1 and Mud2.

CFH CFHR4

5.09e-0627924992636
Pubmed

Retinal changes precede visual dysfunction in the complement factor H knockout mouse.

CFH CFHR4

5.09e-06279223844226
Pubmed

Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy.

CFH CFHR4

5.09e-06279226374608
Pubmed

A gene locus concerned with an antigenic serum substance in Mus musculus.

CFH CFHR4

5.09e-0627924955525
Pubmed

Analysis of complement factor H mRNA expression: dexamethasone and IFN-gamma increase the level of H in L cells.

CFH CFHR4

5.09e-0627922533512
Pubmed

Complement factor H: spatial and temporal expression and localization in the eye.

CFH CFHR4

5.09e-06279216936129
Pubmed

Polymorphisms in BMP2/BMP4, with estimates of mean lung dose, predict radiation pneumonitis among patients receiving definitive radiotherapy for non-small cell lung cancer.

BMP2 BMP4

5.09e-06279228574846
Pubmed

Watching synchronous mitochondrial respiration in the retina and its instability in a mouse model of macular degeneration.

CFH CFHR4

5.09e-06279233558624
Pubmed

Complement factor H Y402H polymorphism results in diminishing CD4+ T cells and increasing C-reactive protein in plasma.

CFH CFHR4

5.09e-06279237940659
Pubmed

Comparative analysis of the properties and ligand binding characteristics of CspZ, a factor H binding protein, derived from Borrelia burgdorferi isolates of human origin.

CFH CFHR4

5.09e-06279219620346
Pubmed

Complement factor H regulates retinal development and its absence may establish a footprint for age related macular degeneration.

CFH CFHR4

5.09e-06279230705315
Pubmed

Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion.

BMP4 CHRDL1

5.09e-06279226976638
Pubmed

A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia.

CFH CFHR4

5.09e-06279233859044
Pubmed

Bone morphogenetic protein-2 and -9 regulate the interaction of insulin-like growth factor-I with growth plate chondrocytes.

BMP2 GDF2

5.09e-06279217549388
Pubmed

Regulation of age-related macular degeneration-like pathology by complement factor H.

CFH CFHR4

5.09e-06279225991857
Pubmed

BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations.

BMP2 BMP4

5.09e-06279223161572
Pubmed

Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.

BMP8B BMP8A

5.09e-0627929463357
Pubmed

The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

5.09e-0627928682296
Pubmed

BMP2 promotes differentiation of nitrergic and catecholaminergic enteric neurons through a Smad1-dependent pathway.

BMP2 SMAD1

5.09e-06279220007850
Pubmed

Serological survey of complement factor H in common laboratory and wild mice: a new third allotype.

CFH CFHR4

5.09e-0627922522412
Pubmed

BMP2 and BMP4 variations and risk of non-syndromic cleft lip and palate.

BMP2 BMP4

5.09e-06279227591802
Pubmed

Absence of complement factor H alters bone architecture and dynamics.

CFH CFHR4

5.09e-06279230107932
Pubmed

Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice.

CFH CFHR4

5.09e-06279234054871
Pubmed

Factor H binding to PspC of Streptococcus pneumoniae increases adherence to human cell lines in vitro and enhances invasion of mouse lungs in vivo.

CFH CFHR4

5.09e-06279217562771
Pubmed

Aged complement factor H knockout mice kept in a clean barriered environment have reduced retinal pathology.

CFH CFHR4

5.09e-06279227397653
Pubmed

Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration.

CFH CFHR4

5.09e-06279229392311
Pubmed

The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation.

CFH CFHR4

5.09e-06279222174452
Pubmed

Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids.

CFH CFHR4

5.09e-06279222875704
Pubmed

Local complement factor H protects kidney endothelial cell structure and function.

CFH CFHR4

5.09e-06279234139209
Pubmed

Circulating FH Protects Kidneys From Tubular Injury During Systemic Hemolysis.

CFH CFHR4

5.09e-06279232849636
Pubmed

Complement factor h is critical in the maintenance of retinal perfusion.

CFH CFHR4

5.09e-06279219541934
Pubmed

Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction.

CFH CFHR4

5.09e-06279217921253
Pubmed

The role of complement dysregulation in AMD mouse models.

CFH CFHR4

5.09e-06279224664701
Pubmed

Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but can be corrected by near infrared light.

CFH CFHR4

5.09e-06279226149919
Pubmed

Murine protein H is comprised of 20 repeating units, 61 amino acids in length.

CFH CFHR4

5.09e-0627922940596
Pubmed

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.

CFH CFHR4

5.09e-06279232165615
Pubmed

Association of bone morphogenetic proteins with otosclerosis.

BMP2 BMP4

5.09e-06279218021008
Pubmed

Cloning of rat type I receptor cDNA for bone morphogenetic protein-2 and bone morphogenetic protein-4, and the localization compared with that of the ligands.

BMP2 BMP4

5.09e-0627928896987
Pubmed

Death by color: differential cone loss in the aging mouse retina.

CFH CFHR4

5.09e-06279224929970
Pubmed

Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.

BMP4 CHRDL1

5.09e-06279218587495
InteractionCHRDL1 interactions

CALCOCO2 BMP4 CHRDL1

8.00e-0611753int:CHRDL1
Cytoband8q24.22

ZFAT TMEM71

3.91e-04177928q24.22
CytobandEnsembl 112 genes in cytogenetic band chr4q23

STPG2 ADH4

1.87e-0337792chr4q23
Cytoband1q32

CFH CFHR4

3.26e-03497921q32
Cytoband1p31.3

L1TD1 ALG6

3.53e-03517921p31.3
GeneFamilyBone morphogenetic proteins|Astacins

BMP2 BMP4 BMP8B BMP8A

2.88e-0811574455
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

FANCB BRCA2 SLX4

3.26e-0520573548
GeneFamilyEndogenous ligands

BMP2 BMP4 BMP8B BMP8A CCL27 GDF2

9.88e-05237576542
CoexpressionNABA_MATRISOME_ASSOCIATED

BMP2 BMP4 BMP8B IL16 TIMP1 CHRDL1 LOXL3 PLXND1 BMP8A CCL27 GDF2 MUC5AC

1.56e-067387712MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

BMP2 BMP4 BMP8B IL16 TIMP1 CHRDL1 LOXL3 PLXND1 BMP8A CCL27 GDF2 MUC5AC

1.87e-067517712M5885
CoexpressionNABA_SECRETED_FACTORS

BMP2 BMP4 BMP8B IL16 CHRDL1 BMP8A CCL27 GDF2

6.83e-06338778MM17064
CoexpressionNABA_MATRISOME

BMP2 BMP4 BMP8B THBS2 IL16 TIMP1 CHRDL1 LOXL3 PLXND1 BMP8A CCL27 GDF2 MUC5AC

6.98e-0610087713MM17056
CoexpressionNABA_SECRETED_FACTORS

BMP2 BMP4 BMP8B IL16 CHRDL1 BMP8A CCL27 GDF2

7.61e-06343778M5883
CoexpressionNABA_MATRISOME

BMP2 BMP4 BMP8B THBS2 IL16 TIMP1 CHRDL1 LOXL3 PLXND1 BMP8A CCL27 GDF2 MUC5AC

8.44e-0610267713M5889
CoexpressionONDER_CDH1_TARGETS_2_DN

SLC7A8 GALNT14 BMP2 GRB14 CRYBG1 INAVA LY75 HS3ST2 CLDN1

1.02e-05473779M4306
CoexpressionBROWNE_HCMV_INFECTION_12HR_DN

THBS2 CRYBG1 DENND2B SPAG5 PLCE1

1.16e-05100775M5775
CoexpressionJI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN

THBS2 TIMP1 LOXL3

1.61e-0517773MM1225
CoexpressionJI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN

THBS2 TIMP1 LOXL3

1.61e-0517773M1767
CoexpressionMATZUK_EMBRYONIC_GERM_CELL

BMP4 BMP8B SMAD1

2.28e-0519773M1821
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_14_PRECICTIVE_ICB_RESPONSE

CFH BMP4 BMP8B BMP8A LY75 CFHR4

2.62e-05198776MM17083
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

TGFB1I1 SLC7A8 TIMP1 WFS1 GPCPD1 PLXND1 PLCE1

9.99e-05365777M39018
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH BMP4 THBS2 IL16 TIMP1 CLDN1

1.31e-06195796c750602c765a51075ba6ede78e3ba80b62374481
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TGFB1I1 CFH RGMA THBS2 L1TD1 CLDN1

1.52e-0620079629054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZFAT DRD4 SPNS3 PPM1J DENND2B

4.91e-061397957e2c10830c3d16109cab3ed0d64b3532481e497d
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH TIMP1 CHRDL1 GDF2 PLCE1

1.20e-05167795c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH TIMP1 CHRDL1 GDF2 PLCE1

1.20e-05167795351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH RGMA THBS2 IL16 L1TD1

1.23e-051687954b2d29a7843bf45922038c093ca7ec0600756adc
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 DGKD LY75 PPM1J TMEM71

1.31e-051707953ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH RGMA THBS2 IL16 L1TD1

1.34e-051717955d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellfacs-Heart-RV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B ZNF296 PPP1R3F SPNS3 LY75

1.38e-051727952dcc9d67d6ecc35940eabbc8ed528f5f884f6976
ToppCellfacs-Heart-RV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B ZNF296 PPP1R3F SPNS3 LY75

1.38e-0517279564d2edbd8e2640b76225597883b1a524e6b1dd3b
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFAT DRD4 ZNF296 SPNS3 PPM1J

1.38e-05172795b84610f1e5889a655652800c2b3270d264bfe1a9
ToppCellfacs-Heart-RV-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B ZNF296 PPP1R3F SPNS3 LY75

1.38e-05172795d061ea21bee179df5a525842e9a48621a8e1461b
ToppCellwk_15-18-Hematologic-Myeloid-pDC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZFAT DRD4 SPNS3 PPM1J FAM217A

1.42e-05173795b571970e3ba88afc07041c5692ccfd85fc39e796
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 CFH BMP4 THBS2 TIMP1

1.46e-0517479595464817adef5ad2038bbf542f315756b7ad862e
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|normal_Lung / Location, Cell class and cell subclass

CFH BMP4 TIMP1 MUC5AC CLDN1

1.54e-05176795f31d7234053085a82cf9d55aeedd1e04d34789c3
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 ZFAT DRD4 SPNS3 PPM1J

1.67e-051797954808469096cd6bec2bdfcf4fc55aa324757600c3
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 ZFAT DRD4 SPNS3 PPM1J

1.67e-051797954d55718c6afd8a038d93cc77b9b08171dab9976f
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL16 ZFAT DRD4 SPNS3 PPM1J

1.72e-051807956a2366d76276452141db1bd93013a9503525f574
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH BMP4 THBS2 TIMP1 LOXL3

1.77e-05181795269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH BMP4 THBS2 TIMP1 LOXL3

1.77e-05181795cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH BMP4 THBS2 TIMP1 LOXL3

1.77e-05181795c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellControl-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

CFH GALNT14 TIMP1 TMEM71 MUC5AC

1.86e-05183795bdd461349a1ef43a015843937d26e8d3571ecc22
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB1I1 BMP2 BMP4 PLXND1 FAM217A

1.91e-05184795087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 TCEA3 ATP13A5 DENND2B PLCE1

1.91e-0518479594748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 TCEA3 ATP13A5 DENND2B PLCE1

1.91e-05184795819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH RGMA BMP2 LOXL3 CREB3L4

1.91e-05184795d754c3de621429b220ae4ac426cdfc619e848462
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL16 ZFAT DRD4 SPNS3 PPM1J

2.01e-05186795d23c3318937492d7d665bec14253124c49181b5a
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH BMP4 THBS2 EPOP CLDN1

2.07e-051877950f90bce2087aecfdbb377e6f46c6e468efbb6e28
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH BMP4 THBS2 EPOP CLDN1

2.07e-0518779576c957b2976d38adb45e07bcf96c689442e1fc20
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH BMP4 THBS2 EPOP CLDN1

2.07e-0518779590a1078b0303799fba5d2ca4fa12076fd75b78b1
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 BMP2 THBS2 TIMP1 ADH4

2.12e-05188795ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

CFH RGMA THBS2 IL16 CHRDL1

2.12e-05188795706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH BMP2 BMP4 DENND2B FAM135B

2.12e-05188795997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH BMP4 THBS2 TIMP1 CLDN1

2.17e-0518979587189275234b5d59484c58acbb14a09903f2b578
ToppCellSevere-MAIT|World / Disease group and Cell class

CFH ATF7IP2 PLXND1 CCL27 TMEM71

2.23e-051907957a92e0d6a021be23125495927b8571e25c83204a
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH THBS2 TIMP1 CHRDL1 HS3ST2

2.29e-05191795f5ce33af56178333730be308253943c54a0724cf
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

CFH BMP4 GRB14 LOXL3 DENND2B

2.34e-051927957a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCell(7)_Epithelial_cells-(7)_Epithelial-G_(Club-Clara_cells)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFH GALNT14 TIMP1 INAVA MUC5AC

2.34e-05192795c7c232545fad8ad327ab94bd0def8dc5daacd03d
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH THBS2 TIMP1 CHRDL1 HS3ST2

2.34e-05192795a8b7c539dc3037071bf068f372e4215563e11de4
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH THBS2 TIMP1 CHRDL1 HS3ST2

2.34e-051927952143e1fad2e88b90d668e12af37b2092d379090f
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH THBS2 TIMP1 CHRDL1 HS3ST2

2.34e-05192795904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|World / Stress and Cell class

TGFB1I1 CFH BMP4 GRB14 LOXL3

2.40e-05193795f31398dad5321a7bcb27e208bd73630e9756e897
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFH GALNT14 TIMP1 INAVA MUC5AC

2.40e-051937958ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CALCOCO2 MARS1 BSN CREB3L4 ADH4

2.40e-05193795088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFH GALNT14 TIMP1 INAVA MUC5AC

2.40e-051937950e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ADORA1 TIMP1 CLDN1 PLCE1

2.46e-0519479543eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

CFH TIMP1 ZNF217 INAVA MUC5AC

2.52e-05195795b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH BMP4 THBS2 TIMP1 ADH4

2.52e-0519579551db90e7611f7d69980878c046505ff34212079b
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH THBS2 TIMP1 CHRDL1 LOXL3

2.59e-05196795fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 CFH TIMP1 CHRDL1 CLDN1

2.59e-05196795023477a499a2c190f363cfdbc9d9c646733a6541
ToppCell(5)_Fibroblast-J_(Lipofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFH ADORA1 GALNT14 THBS2 CLDN1

2.59e-05196795afa29399decd17fda7d63add5039ff778627ccc2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 CFH TIMP1 CHRDL1 CLDN1

2.59e-051967953cb74f1a333a82cac2b459f2f1517e2acf22b5fd
ToppCellNS-moderate-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFH TCEA3 INAVA CLDN1 SMAD1

2.59e-0519679547930de6b47b7bf22d8dae8b7419a9cd1d22f0ea
ToppCellBiopsy_Other_PF-Immune-pDCs|Biopsy_Other_PF / Sample group, Lineage and Cell type

IL16 ZFAT DRD4 SPNS3 PPM1J

2.65e-05197795598a130eb7afb1bb95da64a964218362627feb49
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFH THBS2 IL16 TIMP1 CHRDL1

2.72e-051987953ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CFH RGMA TCEA3 BMP4 DENND2B

2.72e-0519879555e583321f60c95898d93cd0d2615c6692db52ec
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TCEA3 BMP2 THBS2 TIMP1 BMP8A

2.72e-051987956a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB1I1 BMP2 BMP4 TIMP1 DENND2B

2.78e-05199795ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH RGMA WFS1 CHRDL1 CLDN1

2.78e-05199795a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CFH TCEA3 THBS2 TIMP1 BMP8A

2.78e-051997957b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFB1I1 CFH THBS2 TIMP1 CHRDL1

2.78e-0519979566b4ff23b2e83fb7e6a37fdafdef315cfa33d327
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CFH TCEA3 THBS2 TIMP1 BMP8A

2.78e-05199795f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB1I1 CFH BMP4 TIMP1 DENND2B

2.78e-0519979550abd20eb461927fde0ec5caae501d7f2277cf78
ToppCell343B-Fibroblasts|343B / Donor, Lineage, Cell class and subclass (all cells)

TGFB1I1 CFH THBS2 TIMP1 CHRDL1

2.85e-05200795376c1a77031e090be96948b47c78ac0d393f5775
ToppCell5'-Adult-SmallIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB1I1 CFH THBS2 TIMP1 CHRDL1

2.85e-05200795a637281d91e95734ee4f8510b3780e0272b16fda
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CFH GALNT14 THBS2 CHRDL1 CLDN1

2.85e-05200795c082bc21ec7c5323439d108ea8aea510e1113c3f
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CFH TCEA3 BMP4 THBS2 BMP8A

2.85e-052007953c898e81444b001835c3f1bbc68183078701b135
ToppCellTracheal-10x3prime_v2-Stromal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TGFB1I1 CFH THBS2 TIMP1 CHRDL1

2.85e-05200795f74b9b0e27afedd589e828d30194e8417029817a
ToppCelltumor_Lung-Fibroblasts|tumor_Lung / Location, Cell class and cell subclass

TGFB1I1 CFH THBS2 TIMP1 CHRDL1

2.85e-05200795073a68b5ce232203ffee86342cba2a00d907e119
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CFH TCEA3 BMP4 THBS2 BMP8A

2.85e-052007953eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH THBS2 IL16 TIMP1 CHRDL1

2.85e-0520079574e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell(54)_pDC|World / shred on Cell_type and subtype

ZFAT DRD4 CHRDL1 SPNS3 PPM1J

3.06e-05203795b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DRD4 WFS1 PLXND1 SPAG5

6.20e-05120794a6d0406a174d46ce06b41280292931954af88a59
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 CHRDL1 CLDN1 STPG2

1.04e-041377948e2fa2ef8becace96a68bb85c002329110902fbb
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)|Thalamus / BrainAtlas - Mouse McCarroll V32

FANCB TIMP1 PPM1J TMEM71

1.19e-0414279458bfff3284ae21150e4619511bd58622c16c5dde
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)--|Thalamus / BrainAtlas - Mouse McCarroll V32

FANCB TIMP1 PPM1J TMEM71

1.19e-041427945fd737c1fee9d97aee8955f1bf378ead3fce138d
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)-|Thalamus / BrainAtlas - Mouse McCarroll V32

FANCB TIMP1 PPM1J TMEM71

1.19e-0414279416f9945e835c3506b12d904778560d065a50f059
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Pde1c_(Striatum,_iSPNs,_Pde1c_+)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ARHGEF18 PPM1J TMEM269

1.21e-045479334b61e20276ec4dd6b1e25099c2378bf1c372b9a
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Pde1c_(Striatum,_iSPNs,_Pde1c_+)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ARHGEF18 PPM1J TMEM269

1.21e-0454793cbd733e155b29a0a9a05f13382e582e38773489f
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TGFB1I1 ATP13A5 TMEM71 PLCE1

1.51e-04151794527059e47e381b2f6d63c1abb39bc0795ee3829d
ToppCellDendritic_Cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

IL16 CRYBG1 PPM1J SLX4

1.51e-04151794e089bf197ed60e7243160521d4390d4b40a3832b
ToppCellFrontal_cortex-Endothelial-MURAL|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TGFB1I1 ATP13A5 TMEM71 PLCE1

1.51e-041517947570372a315bc312ff57bb5f483375c401ae8787
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH ATP13A5 TMEM71 PLCE1

1.67e-04155794ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH ATP13A5 TMEM71 PLCE1

1.67e-041557940f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH ATP13A5 TMEM71 PLCE1

1.67e-04155794d8b5145258f075b15080f8739f537f48dd22225e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FANCB BRCA2 LOXL3 BMP8A

1.71e-04156794955547dfeb1b1ad4957b4338701055726b22619f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WFS1 GRB14 PLXND1 SPAG5

1.71e-041567942cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GEMIN4 GDF2 FAM135B SPAG5

1.75e-04157794370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCellURO-Other-RBC|URO / Disease, Lineage and Cell Type

TCEA3 ZFAT SPNS3 PPM1J

1.88e-04160794558f3b0719e2461a69e1b93b08e21675e8d07a5a
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ZFAT DRD4 CHRDL1 PPM1J

1.88e-0416079461f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellURO-Other|URO / Disease, Lineage and Cell Type

TCEA3 ZFAT SPNS3 PPM1J

1.88e-04160794b0923e6bacfaba8ca40aa5706bf270eea0938b0a
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ZFAT DRD4 CHRDL1 PPM1J

1.88e-0416079434b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TIMP1 GPCPD1 ZNF217 CLDN1

1.88e-041607946ed37d1fd0304932319d6b942502404115ff36a7
ToppCellLAM-Lymphoid-pDC|LAM / Condition, Lineage and Cell class

ZFAT DRD4 SPNS3 PPM1J

1.93e-04161794bb5b44713e4da4406cdaa79dcf2aa9f97e3cf75a
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCEA3 BMP8A CREB3L4 MUC5AC

2.02e-0416379422fa5d017ff796394394d952ec151e2d1beb8248
ToppCell368C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

TCEA3 ZNF296 PPM1J SLX4

2.02e-04163794299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF296 ATF7IP2 L1TD1 ARHGEF18

2.07e-0416479407d9252b267cb61c6050fbfa5b440aef1349f673
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF296 ATF7IP2 L1TD1 ARHGEF18

2.07e-041647947c016236f0cea38195c1373ebbd2c0b2b2ec81ad
ToppCellE17.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH SLC7A8 BMP2 IL16

2.07e-041647944e9de41ea10ce3233c09e144bfc0453c0ae79fd3
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP4 TIMP1 INAVA LOXL3

2.07e-041647940853e75b60b2a78257b660910c3ee15b09c5f5b0
Drugicariin

BMP2 BMP4 TRIM25 BMP8A GDF2

1.61e-0657795CID005318997
DrugAC1L9Q5W

BMP2 BMP4 BMP8B BMP8A GDF2 SMAD1

1.86e-06106796CID000452221
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

BMP2 BMP4 SMAD1

4.80e-0613773DOID:0050787 (implicated_via_orthology)
DiseaseFanconi anemia

FANCB BRCA2 SLX4

6.09e-0614773cv:C0015625
Diseasegestational blood glucose measurement, fetal genotype effect measurement, parental genotype effect measurement, Glycosuria

TGFB1I1 ARMC5

6.72e-062772EFO_0005939, EFO_0007959, EFO_0009698, HP_0003076
Diseasec3d:C3 ratio

CFH CFHR4

6.72e-062772EFO_0008543
DiseasePeripheral Arterial Diseases

BMP2 BMP8A

6.72e-062772C1704436
DiseaseBone marrow hypocellularity

FANCB BRCA2 SLX4

1.36e-0518773C1855710
Diseasegestational blood glucose measurement, parental genotype effect measurement, Glycosuria

TGFB1I1 ARMC5

2.01e-053772EFO_0005939, EFO_0009698, HP_0003076
Diseasecalnexin measurement

CFH CFHR4

2.01e-053772EFO_0801444
Diseasecomplement factor H-related protein 4A measurement

CFH CFHR4

2.01e-053772EFO_0600057
Diseaseinterleukin-16 measurement

CFH IL16

2.01e-053772EFO_0801717
Diseasehistone-lysine N-methyltransferase 2D measurement

CFH CFHR4

2.01e-053772EFO_0801683
DiseaseFanconi Anemia

FANCB BRCA2 SLX4

3.77e-0525773C0015625
DiseaseNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement

CFH CFHR4

4.02e-054772EFO_0803292
Diseasekallikrein-5 measurement

CFH CFHR4

4.02e-054772EFO_0020515
DiseasePancytopenia

FANCB BRCA2 SLX4

4.25e-0526773C0030312
Diseasediabetes mellitus (implicated_via_orthology)

BMP8B WFS1 BMP8A

4.25e-0526773DOID:9351 (implicated_via_orthology)
DiseaseMiller Dieker syndrome

FANCB BRCA2 SLX4

5.95e-0529773C0265219
DiseaseC-C motif chemokine 27 measurement

CFH CCL27

6.69e-055772EFO_0020198
DiseaseAbnormality of radial ray

FANCB BRCA2 SLX4

8.81e-0533773C4228778
Diseasethrombospondin-2 measurement

CFH THBS2

1.00e-046772EFO_0008299
Diseasecomplement C1s subcomponent measurement

CFH CFHR4

1.00e-046772EFO_0008091
Diseaseotosclerosis (is_implicated_in)

BMP2 BMP4

1.00e-046772DOID:12185 (is_implicated_in)
Diseaseatrial natriuretic factor measurement

CFH CRYBG1

1.40e-047772EFO_0004789
DiseaseAtypical hemolytic-uremic syndrome

CFH CFHR4

2.39e-049772cv:C2931788
DiseaseHemolytic-uremic syndrome

CFH CFHR4

2.39e-049772cv:C0019061
Diseaseleukocyte immunoglobulin-like receptor subfamily A member 5 measurement

CFH CFHR4

2.39e-049772EFO_0801766
Diseasecyclic AMP-responsive element-binding protein 3-like protein 4 measurement

CFH CREB3L4

2.98e-0410772EFO_0801506
DiseaseMarfan syndrome (implicated_via_orthology)

BMP2 BMP4

2.98e-0410772DOID:14323 (implicated_via_orthology)
Diseasetooth agenesis (is_implicated_in)

BMP2 BMP4

2.98e-0410772DOID:0050591 (is_implicated_in)
Diseaseasthma (is_marker_for)

ADORA1 IL16 CCL27 MUC5AC

3.37e-04126774DOID:2841 (is_marker_for)
DiseasePR domain zinc finger protein 1 measurement

CFH BSN

3.64e-0411772EFO_0801904
Diseasehemopexin measurement

CFH CFHR4

3.64e-0411772EFO_0008149
DiseasePrenatal Exposure Delayed Effects

ADORA1 BMP2

4.36e-0412772C0033054
Diseaseneuronal ceroid lipofuscinosis (implicated_via_orthology)

ATP13A5 SPNS3

5.99e-0414772DOID:14503 (implicated_via_orthology)
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

GDF2 SMAD1

5.99e-0414772C1150929
DiseaseC-C motif chemokine 19 measurement

CFH BSN

5.99e-0414772EFO_0008047
DiseaseMYELODYSPLASTIC SYNDROME

FANCB BRCA2 SLX4

7.26e-0467773C3463824
DiseaseFamilial primary pulmonary hypertension

GDF2 SMAD1

8.91e-0417772C0340543
Diseaseschizophrenia, inflammatory bowel disease

TIMP1 INAVA

1.00e-0318772EFO_0003767, MONDO_0005090
Diseasecreatinine measurement

CFH TCEA3 BMP4 ZFAT ARHGEF18 INO80 BSN PPM1J FAM135B

1.13e-03995779EFO_0004518
Diseasetotal blood protein measurement

CFH SLC7A8 DNAH3 TRIM25 DGKD PLCE1

1.14e-03449776EFO_0004536
Diseaseglaucoma (is_marker_for)

CFH MUC5AC

1.24e-0320772DOID:1686 (is_marker_for)
Diseasecoagulation factor measurement

CFH CFHR4

1.24e-0320772EFO_0004634
Diseasegastric ulcer (biomarker_via_orthology)

TIMP1 MUC5AC

1.37e-0321772DOID:10808 (biomarker_via_orthology)
Diseaseprostate carcinoma (is_marker_for)

BMP2 BMP4

1.64e-0323772DOID:10286 (is_marker_for)
Diseaseresponse to interferon

STPG2 PLCE1

1.94e-0325772EFO_0007859
DiseaseAcute monocytic leukemia

FANCB SLX4

2.10e-0326772C0023465
DiseaseColorectal Carcinoma

CALCOCO2 ADORA1 BMP2 BMP4 DNAH3 ZNF217 SPNS3

2.38e-03702777C0009402
Diseasecomplement factor H-related protein 2 measurement

CFH CFHR4

2.61e-0329772EFO_0600055

Protein segments in the cluster

PeptideGeneStartEntry
SCPLCGKPFLSSASL

ARHGEF18

311

Q6ZSZ5
PTAAFLLPPSTACCT

CCL27

21

Q9Y4X3
PPLLLSIFLNSCFSC

ATP13A5

971

Q4VNC0
ITLFCPSCHKPSILT

ADORA1

256

P30542
SFCSTFLSLLPACIK

ALG6

301

Q9Y672
APLCRKCKFCLSPLT

ADH4

96

P08319
FVLKSATLCSLPSCP

EFL1

591

Q7Z2Z2
ACALTLPFICRKPSL

ARMC5

656

Q96C12
PPSCIKTDCLSLPSF

CFH

981

P08603
VCCPTPFLVGLLSSS

DENND2B

941

P78524
IPKACCVPTELSAIS

BMP2

356

P12643
SSIPKACCVPTELSA

BMP4

366

P12644
ACCVPTKLSPISVLY

GDF2

391

Q9UK05
PLSFPNLCSCPLLKS

INO80

956

Q9ULG1
CLLTELPSFLCVASP

INO80

1001

Q9ULG1
FPSPTKCLRCTSLML

CDC42BPG

886

Q6DT37
CDLPPLLKLSCTDTT

OR5I1

181

Q13606
RCTPIPALLFTCIST

SLC7A8

361

Q9UHI5
FPCLKKTESSLLPRC

HS3ST2

311

Q9Y278
FCDLAPLLKLSCSDT

OR1S1

191

Q8NH92
LCLLCSSCLGSPSPS

LOXL3

16

P58215
CLPTTFRPASCLSKT

KRT32

51

Q14532
IAPLPSSTLCPICKT

BSN

161

Q9UPA5
CTAIKNTSFCSSLPP

FAM135A

376

Q9P2D6
PTLCKVLNSTLITCP

PLXND1

1111

Q9Y4D7
SLCCLQFTALLSPPP

OR3A4P

321

P47883
SLLCLPSSISCAQTP

IL16

1001

Q14005
LGKPTDCSTKLPFIC

LY75

916

O60449
VVTTKKACPPLSCSL

MUC5AC

5491

P98088
SSVCSFFLPCPLMLL

DRD4

196

P21917
LFQVCPKSLCVSTPG

PIGK

271

Q92643
FCDLAPLLKLSCSDT

OR1S2

191

Q8NGQ3
VTSLSPLLTFSKFCC

FANCB

581

Q8NB91
CTLLVYCTDLPPTSI

GALNT14

101

Q96FL9
ELKSCLCPTVSRFVP

GPCPD1

636

Q9NPB8
SCPLLNSCLSESPVV

BRCA2

131

P51587
LLCCSCPRKTTSYPT

CLDN1

181

O95832
LKTCPKLTCAFPVSV

CHRDL1

156

Q9BU40
SCCAPLIFVLSPSAD

DNAH3

3516

Q8TD57
STFSLLNCFPCPPAL

EPOP

311

A6NHQ4
AVPKACCAPTKLSAT

BMP8A

361

Q7Z5Y6
SSSPSPLSIKKCPIC

CALCOCO2

386

Q13137
LPTVPCLRTCSKSDI

CFHR4

326

Q92496
ACSLKSSCCPPSVLS

ATF7IP2

161

Q5U623
KASCPPSCTSPLLVF

DGKD

311

Q16760
CCSPFTSVLSADLFP

GRB14

86

Q14449
CVQSPISSFPCTDLK

CRYBG1

481

Q9Y4K1
SCTATCLPFSSVPKE

FAM135B

1036

Q49AJ0
LSPSLIAKDKCCSPI

FAM217A

491

Q8IXS0
AVPKACCAPTKLSAT

BMP8B

361

P34820
CPPSLLCALSFQKST

INAVA

71

Q3KP66
VPCTTLLPCQTLFLT

CREB3L4

176

Q8TEY5
FCEVPPLLLLSCSST

OR13A1

196

Q8NGR1
KRSPACSSLTPSLCK

SPAG5

41

Q96R06
LSPTCIFPSFTCDSL

TMEM71

26

Q6P5X7
LPTCPFSCKCDSRSL

LRTM2

36

Q8N967
PECQSSLPCLKASIS

PLCE1

566

Q9P212
CSSTLPIKPFLSCFP

PPM1J

391

Q5JR12
FLLCSFPAATSPCKI

RGMA

36

Q96B86
CPICGKPFLTLKSRT

SLX4

336

Q8IY92
FHPTTVCKIPSGCSL

SMAD1

366

Q15797
TVFPCLSIPCKLQSG

TIMP1

151

P01033
PCPYASCILASTSLL

TMEM269

146

A0A1B0GVZ9
LPPSSLECSKCCRKF

ZFAT

111

Q9P243
PGLSEKITCAPKTFC

SLFN12L

401

Q6IEE8
EPLICASSLLATAPC

SPNS3

341

Q6ZMD2
GSIIKCFPPACDSTL

STPG2

106

Q8N412
LSCSICLEPFKEPVT

TRIM25

11

Q14258
KSPTLAVPAECVCAL

PPP1R3F

741

Q6ZSY5
LTPTFASSMCLLAPC

TCEA3

166

O75764
CESCLSPILPSDAAK

VPS41

791

P49754
CSLVLSCLCPSASLP

FP248

11

Q71RG6
RTLLTALCFPGPTCT

nan

31

Q5W150
SLSKSLIPSITCPFC

ZNF217

701

O75362
LIPSITCPFCTFKTF

ZNF217

706

O75362
PDHFTCTFCLRPLTK

TGFB1I1

426

O43294
LVPDICFSTSKVPRC

THBS2

596

P35442
PACSILLTNFLCTLP

MARS1

776

P56192
ICTTCETAFKISLPP

GTF2H3

281

Q13889
PTCPVCKKTLSSFSN

ZNF296

231

Q8WUU4
IFSFPIASKDCIPCS

WFS1

416

O76024
TCSPFPLLFSLCQLL

GEMIN4

691

P57678
TGTPCLTLCLASPSK

L1TD1

546

Q5T7N2