Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP12 LRP10 LRP6

4.15e-0516863GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP12 LRP10 LRP6

9.70e-0521863GO:0030228
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC24A5 SLC35A4 KCNK15 SLC49A4 MFSD9 LRP6 SLC39A4 GRID1 SLC35E4 KCNK12 SERINC5 MFSD1 SLC1A5 SLC38A8

4.89e-0411808614GO:0022857
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

B3GNT4 MFNG B4GALNT1 B3GALT6 EXT1

5.23e-04153865GO:0008194
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

SPHK2 FLT1 OXTR LRP6 CD72 SEMA5A GRID1 OR4C13 ADGRE5 TNFRSF19 GPR88 EDA GPR132 PTH1R IL6ST

6.14e-0413538615GO:0004888
GeneOntologyMolecularFunctionL-serine transmembrane transporter activity

SERINC5 SLC1A5

6.47e-049862GO:0015194
GeneOntologyBiologicalProcessglycosaminoglycan biosynthetic process

B3GNT4 PDGFB B3GALT6 EXT1 CHST13

1.46e-0576845GO:0006024
GeneOntologyBiologicalProcessaminoglycan biosynthetic process

B3GNT4 PDGFB B3GALT6 EXT1 CHST13

1.88e-0580845GO:0006023
GeneOntologyBiologicalProcessmucopolysaccharide metabolic process

B3GNT4 PDGFB B3GALT6 EXT1 CHST13

5.52e-05100845GO:1903510
DomainDUF3398

DOCK7 DOCK6

3.03e-046852PF11878
DomainDOCK_C/D_N

DOCK7 DOCK6

3.03e-046852IPR021816
DomainLDLR_class-A_CS

LRP12 LRP10 LRP6

7.96e-0440853IPR023415
DomainDOCK_C

DOCK7 DOCK6

1.10e-0311852IPR010703
DomainDHR-1_domain

DOCK7 DOCK6

1.10e-0311852IPR027007
DomainDHR_2

DOCK7 DOCK6

1.10e-0311852PS51651
DomainDHR_1

DOCK7 DOCK6

1.10e-0311852PS51650
DomainDOCK-C2

DOCK7 DOCK6

1.10e-0311852PF14429
DomainDHR-2

DOCK7 DOCK6

1.10e-0311852IPR027357
DomainDHR-2

DOCK7 DOCK6

1.10e-0311852PF06920
DomainDOCK

DOCK7 DOCK6

1.10e-0311852IPR026791
DomainLdl_recept_a

LRP12 LRP10 LRP6

1.12e-0345853PF00057
Domain-

LRP12 LRP10 LRP6

1.20e-03468534.10.400.10
DomainLDLRA_1

LRP12 LRP10 LRP6

1.36e-0348853PS01209
DomainLDLRA_2

LRP12 LRP10 LRP6

1.44e-0349853PS50068
DomainLDrepeatLR_classA_rpt

LRP12 LRP10 LRP6

1.44e-0349853IPR002172
DomainLDLa

LRP12 LRP10 LRP6

1.44e-0349853SM00192
Domain2pore_dom_K_chnl

KCNK15 KCNK12

2.07e-0315852IPR003280
DomainGlyco_trans_31

B3GNT4 B3GALT6

2.36e-0316852IPR002659
DomainGalactosyl_T

B3GNT4 B3GALT6

2.36e-0316852PF01762
DomainSemaphorin

SEMA5A SEMA4G

3.69e-0320852IPR027231
DomainK_chnl_dom

KCNK15 KCNK12

4.06e-0321852IPR013099
DomainIon_trans_2

KCNK15 KCNK12

4.06e-0321852PF07885
DomainTNFR_NGFR_1

TNFRSF13B TNFRSF19

7.67e-0329852PS00652
DomainTNFR_NGFR_2

TNFRSF13B TNFRSF19

7.67e-0329852PS50050
DomainSema

SEMA5A SEMA4G

8.74e-0331852SM00630
DomainSemap_dom

SEMA5A SEMA4G

8.74e-0331852IPR001627
DomainSema

SEMA5A SEMA4G

8.74e-0331852PF01403
DomainSEMA

SEMA5A SEMA4G

8.74e-0331852PS51004
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

GPR180 LRP12 NPTX1 THADA B4GALNT1 LRP10 SEL1L3 ITGA6 LRP6 B3GALT6 ADGRE5 EXT1 IL6ST GGCX CXADR

3.25e-071201881535696571
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

LRP12 NPTX1 INTS5 THADA LRP10 SMC6 ITGA6 B3GALT6 CCAR2 ADGRE5 EXT1 DOCK6 IL6ST

2.66e-061061881333845483
Pubmed

gp130 in late osteoblasts and osteocytes is required for PTH-induced osteoblast differentiation.

PTH1R IL6ST

6.33e-06288225228504
Pubmed

A strong synergistic epistasis between FAM134B and TNFRSF19 on the susceptibility to vascular dementia.

RETREG1 TNFRSF19

6.33e-06288221127458
Pubmed

Ectodysplasin, Edar and TNFRSF19 are expressed in complementary and overlapping patterns during mouse embryogenesis.

TNFRSF19 EDA

1.90e-05388212972005
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PCNX2 ENGASE SPHK2 INTS5 THADA PLA2G4B KTI12 GRID1 CAMSAP1 DOCK6 FAAP100 SLC1A5

2.22e-051105881235748872
Pubmed

The low-density lipoprotein receptor-related protein 10 is a negative regulator of the canonical Wnt/beta-catenin signaling pathway.

LRP10 LRP6

3.79e-05488220093106
Pubmed

Genes and genotypes affecting the teeth of the mouse.

LRP6 EDA

3.79e-0548825893447
Pubmed

Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development.

TNFRSF19 EDA

6.30e-05588218689798
Pubmed

alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor.

ITGA6 LRP6

6.30e-05588215466886
Pubmed

The Edar subfamily in feather placode formation.

TNFRSF19 EDA

6.30e-05588217362907
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

ITGA6 LRP6 EXT1

6.68e-053188311431694
Pubmed

Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival.

TNFRSF13B ITGA6

9.43e-05688223847204
Pubmed

Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

THADA SRD5A1 MFSD9

1.24e-043888322952603
Pubmed

Genetic interaction between Lrp6 and Wnt5a during mouse development.

HES7 LRP6

1.75e-04888219795512
Pubmed

Risk alleles for multiple sclerosis identified by a genomewide study.

CCAR2 RPL5

1.75e-04888217660530
Pubmed

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

FLT1 PDGFB

2.81e-041088217296941
Pubmed

NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.

TNFRSF19 EDA

3.43e-041188216481354
Pubmed

Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer.

THADA ITGA6

3.43e-041188220878950
Pubmed

Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival.

FLT1 PTH1R

3.43e-041188214722611
Pubmed

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels.

FLT1 PDGFB

3.43e-041188217981115
Pubmed

Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development.

LRP6 EDA

4.11e-041288227864382
Pubmed

FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate.

FLT1 PTH1R

4.85e-041388217014841
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK7 DOCK6

5.65e-041488212432077
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

MFNG HES7

7.42e-041688212617809
Pubmed

Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development.

FLT1 PDGFB

7.42e-041688222627278
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

THADA ZFYVE27 SMC6 DOCK7 CCAR2 CAMSAP1 SLC1A5 CXADR

7.99e-0477788835844135
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

FLT1 DOCK7 ITGA6 ADGRE5 RPL5

8.03e-0428588521423176
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

LRP10 SEL1L3 ITGA6 SLC1A5

8.17e-0416488432409323
Pubmed

The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis.

FLT1 PDGFB

8.40e-041788216107612
Pubmed

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate.

FLT1 PDGFB

8.40e-041788220048339
Pubmed

Platelet-derived growth factor receptors direct vascular development independent of vascular smooth muscle cell function.

FLT1 PDGFB

9.43e-041888218606782
Pubmed

Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".

PDGFB ITGA6 MMP3 IL6ST

9.75e-0417288420628624
Pubmed

Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage.

SEMA5A SEMA4G

1.05e-031988215051154
Pubmed

Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis.

FLT1 PDGFB

1.05e-031988211331305
Pubmed

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

THADA ITGA6

1.05e-031988219767753
Pubmed

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.

FLT1 LRP6

1.05e-031988221623369
Pubmed

FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells.

FLT1 PDGFB

1.17e-032088225091710
Pubmed

Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.

THADA ITGA6

1.17e-032088220564319
Pubmed

Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

MMP3 PTH1R

1.17e-032088220495570
Pubmed

Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells.

FLT1 PDGFB

1.29e-032188221593423
Pubmed

Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180.

FLT1 PDGFB

1.29e-032188218508041
Pubmed

Mekk3 is essential for early embryonic cardiovascular development.

FLT1 PDGFB

1.29e-032188210700190
Pubmed

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).

FLT1 OXTR PDGFB MMP3

1.30e-0318688420673868
Pubmed

Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

FLT1 OXTR PDGFB MMP3

1.30e-0318688420452482
Pubmed

FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod.

FLT1 PTH1R

1.41e-032288217544391
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

DOCK7 LRP6 RPL5 SLC1A5

1.76e-0320288424639526
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ZFYVE27 RETREG1 ITGA6 DOCK6 GGCX CXADR

1.79e-0350488634432599
Pubmed

Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.

SEMA5A SEMA4G

1.98e-032688239152101
Pubmed

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

THADA PTH1R IL6ST

2.06e-039988319730683
Pubmed

Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation.

MMP3 PTH1R

2.13e-032788211566859
Pubmed

Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults.

SLC24A5 CCAR2

2.13e-032788225133637
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

INTS5 THADA DOCK7

2.24e-0310288311214970
Pubmed

Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

FLT1 PDGFB

2.29e-032888218593464
Pubmed

Extra-embryonic vasculature development is regulated by the transcription factor HAND1.

FLT1 PDGFB

2.29e-032888215073150
Pubmed

Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice.

FLT1 PDGFB

2.46e-032988217573777
Pubmed

Noggin is required for correct guidance of dorsal root ganglion axons.

SEMA5A SEMA4G

2.46e-032988212435358
GeneFamilyLow density lipoprotein receptors

LRP12 LRP10 LRP6

8.31e-0613573634
GeneFamilyBeta 3-glycosyltransferases

B3GNT4 MFNG B3GALT6

5.74e-0524573426
GeneFamilySolute carriers

SLC24A5 SLC35A4 SLC49A4 SLC39A4 SLC35E4 SLC1A5 SLC38A8

2.32e-04395577752
GeneFamilyPotassium two pore domain channel subfamily K

KCNK15 KCNK12

9.99e-0415572277
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA5A SEMA4G

1.79e-0320572736
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF13B TNFRSF19

3.75e-0329572782
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT1 LMTK3

7.05e-0340572321
GeneFamilyADAM metallopeptidase domain containing|CD molecules

TNFRSF13B ITGA6 CD72 ADGRE5 IL6ST

7.93e-03394575471
CoexpressionDAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN

GAS2 SLC39A4 ADGRE5 EXT1 SLC1A5 PTH1R OPLAH

2.27e-06179877M8519
ToppCellHealthy/Control-CD4+_T_naive|Healthy/Control / Disease group and Cell class

RETREG1 ITGA6 LRP6 SERINC5 EDA RPL5 IL6ST

1.05e-07193877f5face746df3517c86d72e31ba8f1b78c4c6b481
ToppCellHealthy/Control-CD4+_T_naive|World / Disease group and Cell class

RETREG1 ITGA6 LRP6 SERINC5 EDA RPL5 IL6ST

1.05e-071938776218e6cbe44d92bb98d42ef2f5e18ab7a683b100
ToppCellHealthy_donor-CD4+_T_naive|World / disease group, cell group and cell class (v2)

RETREG1 ITGA6 LRP6 SERINC5 EDA RPL5 IL6ST

1.09e-07194877bcaaa6b6ce5b3552f11311d8ee91c35b8ec065f8
ToppCellHealthy_donor-CD4+_T_naive|Healthy_donor / disease group, cell group and cell class (v2)

RETREG1 ITGA6 LRP6 SERINC5 EDA RPL5 IL6ST

1.09e-07194877a8a0368a4e0eb5654fdffc8a779b08ad402aa2eb
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Artery|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FLT1 TSPAN11 OXTR PDGFB SEL1L3 ITGA6 DOCK6

1.34e-0720087777ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Pvalb_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

TSPAN11 GREB1 GPR88 DCST1 GPR132

7.85e-0787875fd0df79b02f96463a6bad90dcd019c59c8e3eb0e
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 RETREG1 TNFRSF13B CD72 SLC39A4 TNFRSF19

1.46e-0618087686cdb1652f1736c38b501f07cf40ce99134cf597
ToppCellfacs-SCAT-Fat-24m-Lymphocytic|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 RETREG1 TNFRSF13B CD72 SLC39A4 TNFRSF19

1.46e-06180876115ce9f048f933704a19759948dcc933245e63c4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.12e-0619287632927ef3b93e0497e9bbe63c2754da03cf178202
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

GAS2 LRP6 TNFRSF19 GREB1 SERINC5 EDA

2.12e-06192876916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.18e-06193876d169fdc704c66f26d53457f4de3a22de0811e240
ToppCellmild_COVID-19-CD4+_T_naive|mild_COVID-19 / disease group, cell group and cell class (v2)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.18e-0619387640fc4a519c883c6c269a9c05be36ae906f75426a
ToppCellmild_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.18e-0619387642ddacc55658ea6ba4248ac19c9c3709f342b4f5
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

GAS2 LRP6 TNFRSF19 GREB1 SERINC5 CXADR

2.18e-06193876503a979328c68b096680b71359a26f02fafdff35
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD4+_T_naive|COVID-19_Mild / Disease group, lineage and cell class

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.31e-061958768aec807b24bcebf1a8011d676d2143b6fc570f1d
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.31e-06195876d9965223430aba1ec0b1b77b5bd40d3a01e42e95
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.31e-06195876d056c806c7ad38ca425bdaa44385424a7f43f915
ToppCellCOVID-19_Moderate-CD4+_T_naive|World / disease group, cell group and cell class

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.31e-0619587638d65cf0895f7a99d789ec3dcbd56a7506706d38
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.31e-061958769c71d2a58e772b556e22e2f1d60593580b7aafd8
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.31e-061958761d3c51a3be5ad1fbc465c5f684565ec4c6f35f54
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.31e-061958766421d949bfebcd985bea7efc5731a1ca79350b61
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.38e-06196876ffc2728663a72ec62fa2e5b1054368fb56d18c62
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.38e-06196876b999759051499b725d02d919a89234a4467df35c
ToppCellCOVID-19_Moderate-CD4+_T_naive|COVID-19_Moderate / disease group, cell group and cell class

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.38e-06196876b1a463cf4cf3755086f3420b8892d493af8cacbe
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD4+_T_naive|COVID-19_Severe / Disease group, lineage and cell class

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-0619787607f74bdadfd28e1d55b3f4a3bf87d5dd65a2e9c5
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-061978769f0d91bb7aec4f2442259eca1ddf7905f8d40e9b
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-06197876442fb5ee17e6d4d8c280721b21fd3f7ba6475951
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-06197876258dfe69b5faeaee709422f873b144ca5e4a6452
ToppCellCOVID-19_Mild-CD4+_T_naive|COVID-19_Mild / Disease condition and Cell class

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-061978763aea21819cbedb3bcdb74ae2e7f963a44b53ed52
ToppCell10x5'-blood-Lymphocytic_T_CD4-Tnaive/CM_CD4|blood / Manually curated celltypes from each tissue

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-0619787633a7f3358393eeeb8f8c1098fd4de54f74d68c59
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-06197876bf80e39cd68fd5bb85c8726d4f82648391de74ad
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-06197876296b27348ca7e9acf746f752cf810e4e5baea76c
ToppCellCOVID-19_Severe-CD4+_T_naive|COVID-19_Severe / Disease condition and Cell class

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.46e-06197876ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4|bone_marrow / Manually curated celltypes from each tissue

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.53e-0619887617423052045de72e8827e6ce7f0e38ce8ab5f370
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4|bone_marrow / Manually curated celltypes from each tissue

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.53e-06198876f2d85d7ca0e867d20ad4d2b1cbbfd91a066c1a03
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-Tnaive/CM_CD4|bone_marrow / Manually curated celltypes from each tissue

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.68e-06200876a52d545e94b9bc3ee4b333c5bf7e279bf5650b55
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tnaive/CM_CD4|lymph-node_spleen / Manually curated celltypes from each tissue

RETREG1 ITGA6 SERINC5 EDA RPL5 IL6ST

2.68e-0620087639d60ec4b125b4ff905a2c6a0f2d6923b8d64227
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLT1 TSPAN11 OXTR ITGA6 TNFRSF19 DOCK6

2.68e-06200876b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellsevere_influenza-CD4+_T_naive|World / disease group, cell group and cell class (v2)

RETREG1 ITGA6 EDA RPL5 TMEM139

1.47e-051588758ab3d8a9b7a1daa890d76dde1d6182af40b70021
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4|Liver / Manually curated celltypes from each tissue

KCNK15 ITGA6 EDA RPL5 IL6ST

1.92e-05167875ab6273ae5d76a3f9a05c58320e3dee80f9b99e47
ToppCellICU-SEP-Lymphocyte-B-B_intermediate|ICU-SEP / Disease, Lineage and Cell Type

SMC6 SEL1L3 TNFRSF13B CD72 TNFRSF19

2.15e-051718752e44bf6f3d90193e7cadcac48bb852bd632a81bc
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMC6 SEL1L3 TNFRSF13B CD72 TNFRSF19

2.27e-05173875f135cc9dcf34f33ced3210171ab40ae6d77cfae0
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMC6 SEL1L3 TNFRSF13B CD72 TNFRSF19

2.27e-0517387523248019c819f6e38337dcc4edb763ef1992e89e
ToppCellCOVID-19_Moderate-B_intermediate|COVID-19_Moderate / disease group, cell group and cell class

FLT1 SMC6 SEL1L3 TNFRSF13B CD72

2.53e-0517787568e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCellChildren_(3_yrs)-Immune-B_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SMC6 SEL1L3 TNFRSF13B CD72 FRMPD3

2.75e-0518087540a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCellCOVID-19_Moderate-B_intermediate|World / disease group, cell group and cell class

FLT1 SMC6 SEL1L3 TNFRSF13B CD72

2.75e-05180875bd81b87a6dc81e5ab4a6c948eb0c80f14401a6a7
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RETREG1 TNFRSF13B CD72 SLC39A4 TNFRSF19

2.82e-0518187514faef1dde781d501834379f2a6413e8d6a80b72
ToppCellfacs-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 RETREG1 SEMA5A SLC39A4 SLC1A5

2.90e-0518287545faefd7cbeac84d2c58650530b902af6ce921f8
ToppCelldroplet-Fat-Scat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MFNG PDGFB DCST1 PTH1R

2.90e-05182875fea094fe0e7796c084e60b5310c1559658633f7a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

RETREG1 ITGA6 SERINC5 EDA IL6ST

2.97e-05183875f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SMC6 SEL1L3 TNFRSF13B CD72 TNFRSF19

2.97e-0518387501664fce6b70a02c9d39d747b6a6aabc86d57bc2
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

LRP12 B4GALNT1 SEL1L3 ITGA6 SERINC5

3.05e-051848759c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RETREG1 ITGA6 SERINC5 EDA IL6ST

3.05e-051848755350b58aa9979631228835d11eb45ddf81d08bff
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 ITGA6 CCAR2 DOCK6 IL6ST

3.13e-05185875bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

THADA HLTF TNFRSF13B B3GALT6 SLC35E4

3.30e-05187875689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 RETREG1 SEMA5A SLC39A4 TNFRSF19

3.30e-051878759aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-Progen|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.30e-0518787516fffe894a2c7d5186556ad000e0be229511fbdb
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

RETREG1 ITGA6 SERINC5 EDA IL6ST

3.38e-05188875b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-naive_B_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SMC6 SEL1L3 TNFRSF13B CD72 LMTK3

3.38e-0518887531129152386e9aba16f749d78da12a08b916e6f8
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FLT1 MFNG PDGFB SEL1L3 ITGA6

3.38e-05188875b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RETREG1 SERINC5 EDA RPL5 IL6ST

3.38e-051888752b630b0609d4ac61338d6533cb7893cfe1241e44
ToppCellMultiple_Sclerosis-Lymphocyte-B-B_intermediate|Multiple_Sclerosis / Disease, Lineage and Cell Type

SMC6 SEL1L3 TNFRSF13B CD72 DOCK6

3.38e-05188875ee1bb0700ab70e03a63982446a33976b9200ddb6
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA5A SLC39A4 TNFRSF19 CXADR OPLAH

3.38e-05188875842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA5A SLC39A4 TNFRSF19 CXADR OPLAH

3.38e-05188875a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|(2)_5-FU / Stress and Cell class

FLT1 MFNG ITGA6 IL6ST CXADR

3.47e-051898750f169b17bb26a812a5b0dcd6e29a3ca8415fd197
ToppCellsevere_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

RETREG1 ITGA6 SERINC5 EDA IL6ST

3.65e-0519187555a282478488efd1561ea57a6f0218f55f711bb0
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.65e-05191875fda432a7f79664e8ffd5d03c1c69ec43bbac994b
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD4_Naive|Leuk-UTI / Disease, Lineage and Cell Type

RETREG1 ITGA6 LRP6 RPL5 IL6ST

3.74e-05192875ecdcb210a448495fc141ddc946cca1fbd821ad83
ToppCellBLOOD--(2)_Memory_B_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SMC6 SEL1L3 TNFRSF13B CD72 DOCK6

3.74e-051928759c3a4699f05f1a757d6e37d9f15675e970584cca
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RETREG1 ITGA6 SERINC5 EDA IL6ST

3.74e-0519287578546a6e077076834fd717607610ab6df3b6e7ba
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FLT1 MFNG PDGFB SEL1L3 ITGA6

3.83e-05193875643f992dbce639e7d147924d8b8f455fcebf215a
ToppCellfacs-Marrow-B-cells-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF13B CD72 TNFRSF19 SERINC5 SLC1A5

3.83e-0519387524c34c6635eb7fc2878282803c421b64320e77d8
ToppCellControl-Lymphocyte-T_NK-CD4_Naive|Control / Disease, Lineage and Cell Type

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.83e-05193875643ee12ab81d4f6c97633872f4123b90a1846d50
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.83e-05193875792315f409a57fa6a8a88c850060b1e089e062ea
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FLT1 MFNG PDGFB SEL1L3 ITGA6

3.83e-0519387501c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.93e-051948752e2019a7bf57f257f0ff9b24eacff59dbb952ebb
ToppCellmild-Lymphocytic-B_cells_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SMC6 SEL1L3 TNFRSF13B CD72 RPL5

3.93e-05194875fad1986cba9cd23ac68e639d7335fbcd6ae2a4e7
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMC6 SEL1L3 TNFRSF13B CD72 RPL5

3.93e-05194875d37fb6cbcc4f3872137942ae63812e3dbe3c3076
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.93e-05194875d788d5bd1e651706e7e2d54ada546a5e84f86ff0
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMC6 SEL1L3 TNFRSF13B CD72 RPL5

3.93e-05194875138a1796dc6c86d84a49ba264ff27ddbc6058517
ToppCellsevere-CD4+_Tcm|severe / disease stage, cell group and cell class

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.93e-05194875380fbd19b72af6767f98bbf50329686b76d59c54
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FLT1 MFNG PDGFB SEL1L3 ITGA6

3.93e-0519487532ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD8+_T_naive|COVID-19_Severe / Disease group, lineage and cell class

RETREG1 ITGA6 SERINC5 EDA RPL5

3.93e-051948756aeedfdb2b526913937eea978ddcbab8be4e49a6
ToppCellsevere_COVID-19-CD4+_T_naive|severe_COVID-19 / disease group, cell group and cell class (v2)

RETREG1 ITGA6 SERINC5 EDA RPL5

3.93e-051948754b86f3cc173ea779399d5b3598b45b25f60a4395
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.93e-05194875e0ccf18edbae09fc1068f1e923f1bc0d0ff44195
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.93e-0519487531a98ce929ee6cf6a9747e384f9a06336af49fd5
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.93e-05194875fc0504730ae576ff46ba0bc9f585c53ab78d914c
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.93e-0519487589e30624e389ff7b4a3b6e02d2b77cdeae263ded
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FLT1 MFNG PDGFB SEL1L3 ITGA6

3.93e-0519487553a5e8863d79a052dff0758f389be5ac3883c721
ToppCellControl-Lymphoid_T/NK-CD4+_T_naive|Control / Disease group, lineage and cell class

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

3.93e-05194875aabcd9f71d8ef54add5c46d8a3e226e3ae3ab124
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

4.02e-051958754e114f6399863406bd87220dea7fb7dfd08824bd
ToppCelldistal-Hematologic-Plasma-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEL1L3 TNFRSF13B KCNK12 GREB1 LMTK3

4.02e-051958754280a5bc5ed9bb12e278b182e0be6cb88fa83d83
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FLT1 MFNG PDGFB SEL1L3 ITGA6

4.02e-051958753826bfafe85f8aa9a508202ceb2b02e81b090498
ToppCellnormal-na-Lymphocytic_T-T4_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

4.12e-05196875feb1c768cf66c64b6c892905d2d865946e70812f
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FLT1 MFNG TSPAN11 PDGFB ITGA6

4.12e-051968752a2a93b89dcb98043cb1f8b422ac8c55e2edc37b
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-T4_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

4.12e-05196875afafd3de2bc3a62d5dcd33801d7ec8f3f98fb7d2
ToppCellcontrol-Lymphocytic-CD4_T_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

4.12e-051968754f8670257ea6fdf58cb102b4c7dc9ba39bb317ef
ToppCellControl-CD4+_T_naive|Control / Disease condition and Cell class

RETREG1 ITGA6 SERINC5 RPL5 IL6ST

4.12e-0519687510455dd24d4a4466eeecb22949b83085e8333ad2
ToppCelldroplet-Marrow-BM-1m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 CD72 TNFRSF19 SLC1A5 RNF26

4.12e-05196875ef1482f83872af72a55b6c5b5a1491e6f7f44dd7
ToppCelldistal-Hematologic-Plasma|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEL1L3 TNFRSF13B KCNK12 GREB1 LMTK3

4.12e-051968752a11dc1e51c64af7705e1622a9da583a6634c563
DrugClemizole hydrochloride [1163-36-6]; Down 200; 11uM; MCF7; HT_HG-U133A

ENGASE LRP12 OXTR PDGFB RETREG1 ITGA6 LRP6 GREB1 IL6ST

7.07e-081998794695_DN
Diseaseprostatic hypertrophy (is_implicated_in)

PDGFB SRD5A1

2.40e-053842DOID:11132 (is_implicated_in)
Diseasebackground diabetic retinopathy (is_marker_for)

FLT1 PDGFB

4.79e-054842DOID:13208 (is_marker_for)
DiseaseLeydig cell tumor (is_marker_for)

FLT1 PDGFB

2.22e-048842DOID:2696 (is_marker_for)
Diseasetooth agenesis (is_implicated_in)

LRP6 EDA

3.55e-0410842DOID:0050591 (is_implicated_in)
DiseaseOligodontia

LRP6 EDA

5.19e-0412842C4082304
Diseaselevel of Phosphatidylinositol (18:1_18:1) in blood serum

DOCK7 DOCK6

6.12e-0413842OBA_2045159
Diseasebasophil measurement

THADA EXT1 GGCX

6.77e-0460843EFO_0803539
DiseaseHypodontia

LRP6 EDA

7.13e-0414842C0020608
DiseaseKuhnt-Junius degeneration (is_marker_for)

FLT1 PDGFB

7.13e-0414842DOID:10873 (is_marker_for)
Diseaseproliferative diabetic retinopathy (is_marker_for)

FLT1 PDGFB

9.36e-0416842DOID:13207 (is_marker_for)
Diseaselevel of Phosphatidylinositol (18:0_18:1) in blood serum

DOCK7 DOCK6

1.19e-0318842OBA_2045155
DiseaseDyschondroplasias

FLT1 PTH1R

1.33e-0319842C0013366
DiseaseDisproportionate short stature

B3GALT6 EXT1 PTH1R

1.40e-0377843C0878659
Diseaselevel of Phosphatidylinositol (18:0_18:2) in blood serum

DOCK7 DOCK6

1.62e-0321842OBA_2045156
Diseasecardiac troponin I measurement

PCNX2 MFNG GRID1 GREB1

1.63e-03176844EFO_0010071
Diseaseresponse to xenobiotic stimulus

THADA SRD5A1 SMC6 MFSD9

1.84e-03182844GO_0009410
Diseaselevel of Phosphatidylinositol (18:0_20:4) in blood serum

DOCK7 DOCK6

1.95e-0323842OBA_2045158
DiseaseHDL cholesterol change measurement

GRID1 DOCK6

2.12e-0324842EFO_0007805
Diseaseglioblastoma (is_implicated_in)

PDGFB RPL5

2.12e-0324842DOID:3068 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
LLLSSPGLEELYRCC

CCAR2

311

Q8N163
LLALLCILCRLCVYS

EDDM3A

11

Q14507
LCGAALLYLARCAAE

B3GALT6

21

Q96L58
RLGKYILCCLLGHAI

SLC1A5

301

Q15758
LVLLLACASLGLLYA

B4GALNT1

11

Q00973
TRVGLALSLFCLLLC

ADGRE5

551

P48960
TCLRYLLLGLLLTCL

CD72

91

P21854
LLLSSELYCRVCSLI

CAMSAP1

81

Q5T5Y3
LDSRLLIFPLYICCN

GMCL1

491

Q96IK5
AARTCALLALCLLGA

NPTX1

6

Q15818
LSGLSVLLLCCVFLL

GPR88

281

Q9GZN0
LVIALGCTCKLYAIR

LRP10

456

Q7Z4F1
LLLVIALGCTCKLYS

LRP12

506

Q9Y561
CSDLLFSGLLLYLCD

GREB1

1866

Q4ZG55
LYCLARAARTPLCLV

KTI12

91

Q96EK9
SLLACILLSALGYLL

MFSD9

111

Q8NBP5
VRAAGLVLCTLCYLL

KCNK15

6

Q9H427
LVLCTLCYLLVGAAV

KCNK15

11

Q9H427
ILLLLCVAVCSAYPL

MMP3

6

P08254
CSGLLAFIFLLLTCL

LMTK3

46

Q96Q04
ALFLSLCCYLRLVSA

PDGFB

6

P01127
SRPIYFCVLCGLILL

PCNX2

906

A6NKB5
VLLILGLFAVLLSCC

KCNK12

216

Q9HB15
LLAFVLLCTLLGLGC

PINLYP

11

A6NC86
CSFCVLLRAAPLLLY

LRP6

11

O75581
TCILSLICALALAYL

MFSD1

221

Q9H3U5
SNCLAVFRLGLLLDC

KLHL40

131

Q2TBA0
GSLVLCSLCLRNRYL

LRRC42

146

Q9Y546
QLCLLYLSAGLLSRL

ITGA6

6

P23229
LCLLDVGYLINTSCL

PLA2G4B

611

P0C869
ICLALSLGCGLYQII

GPR180

331

Q86V85
SGFICLLNCLLLLVS

OR4C13

201

Q8NGP0
LCLILLLALSGNACV

OXTR

46

P30559
LYALCARRGLYCLSL

FAAP100

76

Q0VG06
LALHLLTLCCYLELR

EDA

51

Q92838
CLAFLLTTLLGVLFC

IL6ST

626

P40189
LGRLLDLLYLCLAAF

DOCK6

1281

Q96HP0
LNRLLDLLYLCVSCF

DOCK7

1356

Q96N67
RYFILLSAGSCLALL

EXT1

6

Q16394
YSLAVLLLGCLLFLR

B3GNT4

36

Q9C0J1
LVCLCLLQAFGYRLR

DCST1

561

Q5T197
GSCLLSLLLILCFRE

SLC49A4

451

Q96SL1
CLIAGYCRLLLDSRK

FRMPD3

481

Q5JV73
TLLALALIGLIIFCC

CXADR

246

P78310
YVGLGISICSLILCL

ADGRF2

451

Q8IZF7
CILAIGLLLACLVAA

GRID1

836

Q9ULK0
VSLRGCLLLDLLVCF

ENGASE

571

Q8NFI3
LGLLLRLRQICCHTY

HLTF

706

Q14527
CYLSGFRECLLRLAA

HES7

91

Q9BYE0
RSCLVAACLLLYLSD

CDKN3

146

Q16667
LNAGLDLYLCLISSC

SDIM1

76

Q6ZPB5
LLCMGLLCLRYHLNL

MFNG

16

O00587
TLGLECCLLYLSKTI

PBOV1

116

Q9GZY1
LLCLALCELLYTGTL

GPR132

81

Q9UNW8
GCLYNLISLACVDRL

NRIP3

126

Q9NQ35
CVLLVLALGLYCGRA

NRAC

111

Q8N912
CLCLLELGRIAARYG

GAS2

146

O43903
RAVYIDILFLLTCCL

THADA

1456

Q6YHU6
GGRSACALLLLCYLN

SEL1L3

41

Q68CR1
CALLLLCYLNVVPSL

SEL1L3

46

Q68CR1
GVILSYLLLLCAFLC

RETREG1

216

Q9H6L5
TLSALIYCLRCLVGR

OPLAH

1031

O14841
RYLYGSLATLLICLC

SLC39A4

326

Q6P5W5
SLATLLICLCAVFGL

SLC39A4

331

Q6P5W5
LLYSCCSGLESLKLL

RNF26

86

Q9BY78
IGLYSCLSPLVCRLS

SPPL2C

291

Q8IUH8
AAAYCTGLLLARRLL

RPL5

96

P46777
FILSLLFCCYLIRLR

RNF24

36

Q9Y225
LCYCSVLLRGLLAAL

INTS5

871

Q6P9B9
ALVSVLSLLACCLIY

SLC38A8

251

A6NNN8
LSLLACCLIYSLTGV

SLC38A8

256

A6NNN8
LGCLLTLLVYTYCQR

SEMA5A

981

Q13591
CLLLLTLALCCYRAN

SCGB1D1

6

O95968
LAAACLGAALLLLCA

CHST13

11

Q8NET6
CSAFLLSLLILIVYC

CMTM6

76

Q9NX76
AALRLLTYLSCRFGL

TICRR

26

Q7Z2Z1
LGLCYRISCVLFLLP

GGCX

131

P38435
GLCLILASSLLYVAC

SEMA4G

686

Q9NTN9
LGLDLLLNCSLLLCR

SPHK2

296

Q9NRA0
ALLLCCPVLSSAYAL

PTH1R

11

Q03431
LGTSLLIGCILYSCL

SERINC5

316

Q86VE9
IITTCGQLLLLRYCG

SFMBT2

96

Q5VUG0
AIYNLLGICAACGLL

SLC24A5

146

Q71RS6
LKIGSTAVLYCLCLR

SLC35A4

121

Q96G79
CLTLRCKLYFDNLLS

SMC6

936

Q96SB8
LVGLVCIFLALCLDL

TMEM47

21

Q9BQJ4
CIFLALCLDLGAVLS

TMEM47

26

Q9BQJ4
RKGCLSTYFCLLLVI

TSPAN11

86

A1L157
ALVYSTLGLCLCAVL

TNFRSF13B

161

O14836
LCSLLTCLGLNVLFL

ZFYVE27

71

Q5T4F4
LLVLLGYLSCKVTCE

TNFRSF19

16

Q9NS68
RLLAALAYLQCAVGC

SRD5A1

11

P18405
ACILLSCLLSVLYNL

SLC35E4

256

Q6ICL7
DTGVLLCALLSCLLL

FLT1

6

P17948
LLCCASFLLGLALLG

TMEM139

16

Q8IV31