Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

2.96e-06411105GO:0015175
GeneOntologyMolecularFunctionL-leucine transmembrane transporter activity

SLC43A2 SLC7A8 SLC7A5

3.21e-0661103GO:0015190
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TMEM94 RYR2 SLC30A6 ITPR2 ITPR3 SLC38A2 SLC41A2 SLC12A9 PKD1 SLC28A2 SLC29A1 SLC38A3

9.86e-0646511012GO:0046873
GeneOntologyMolecularFunctionactive transmembrane transporter activity

TMEM94 SLC6A17 ABCB1 SLC30A6 SLC7A8 SLC38A2 SLC12A9 SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

1.27e-0547711012GO:0022804
GeneOntologyMolecularFunctionbranched-chain amino acid transmembrane transporter activity

SLC43A2 SLC7A8 SLC7A5

1.90e-05101103GO:0015658
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC43A2 TMEM94 SLC6A17 PIEZO1 RYR2 ABCB1 SLC30A6 ITPR2 ITPR3 SLC7A8 SLC38A2 SLC41A2 SLC12A9 PKD1 SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

2.24e-05118011019GO:0022857
GeneOntologyMolecularFunctionUDP-N-acetylglucosamine diphosphorylase activity

UAP1 UAP1L1

3.01e-0521102GO:0003977
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A17 SLC30A6 SLC7A8 SLC38A2 SLC12A9 SLC28A2 SLC7A5 SLC29A1 SLC38A3

3.84e-052961109GO:0015291
GeneOntologyMolecularFunctionaromatic amino acid transmembrane transporter activity

SLC43A2 SLC7A5 SLC38A3

4.47e-05131103GO:0015173
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

4.51e-05711105GO:0015179
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TMEM94 PIEZO1 RYR2 SLC30A6 ITPR2 ITPR3 SLC38A2 SLC41A2 SLC12A9 PKD1 SLC28A2 SLC29A1 SLC38A3

7.42e-0566411013GO:0008324
GeneOntologyMolecularFunctiontransporter activity

SLC43A2 TMEM94 SLC6A17 PIEZO1 RYR2 ABCB1 SLC30A6 ITPR2 ITPR3 SLC7A8 SLC38A2 SLC41A2 SLC12A9 PKD1 SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

7.42e-05128911019GO:0005215
GeneOntologyMolecularFunctionalanine transmembrane transporter activity

SLC7A8 SLC38A2 SLC38A3

8.65e-05161103GO:0022858
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR2 ITPR3

8.99e-0531102GO:0005220
GeneOntologyMolecularFunctiondiacylglycerol diphosphate phosphatase activity

PLPP5 PLPP4

8.99e-0531102GO:0000810
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

9.55e-05831105GO:0015101
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR2 ITPR2 ITPR3

1.25e-04181103GO:0015278
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC43A2 ABCB1 SLC7A8 SLC38A2 SLC7A5 ABCC2 SLC38A3

1.50e-042071107GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC43A2 ABCB1 SLC7A8 SLC38A2 SLC7A5 ABCC2 SLC38A3

1.55e-042081107GO:0005342
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TMEM94 RYR2 SLC30A6 ITPR2 ITPR3 SLC38A2 SLC41A2 SLC12A9 PKD1 SLC28A2 SLC29A1 SLC38A3

1.76e-0462711012GO:0022890
GeneOntologyMolecularFunctionnucleoside:sodium symporter activity

SLC28A2 SLC29A1

1.79e-0441102GO:0005415
GeneOntologyMolecularFunctionpurine nucleoside transmembrane transporter activity

SLC28A2 SLC29A1

1.79e-0441102GO:0015211
GeneOntologyMolecularFunctionnucleobase:monoatomic cation symporter activity

SLC28A2 SLC29A1

1.79e-0441102GO:0015391
GeneOntologyMolecularFunctionpyrimidine- and adenosine-specific:sodium symporter activity

SLC28A2 SLC29A1

1.79e-0441102GO:0015389
GeneOntologyMolecularFunctionsymporter activity

SLC6A17 SLC38A2 SLC12A9 SLC28A2 SLC29A1 SLC38A3

1.83e-041501106GO:0015293
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TMEM94 RYR2 SLC30A6 ITPR2 ITPR3 SLC38A2 SLC41A2 SLC12A9 PKD1 SLC28A2 ABCC2 SLC29A1 SLC38A3

2.74e-0475811013GO:0015318
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

2.89e-041051105GO:0015171
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TMEM94 PIEZO1 RYR2 SLC30A6 ITPR2 ITPR3 SLC38A2 SLC41A2 SLC12A9 PKD1 SLC28A2 SLC29A1 SLC38A3

4.21e-0479311013GO:0015075
GeneOntologyMolecularFunctionuridine transmembrane transporter activity

SLC28A2 SLC29A1

4.45e-0461102GO:0015213
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC38A2 SLC12A9 SLC28A2 SLC29A1 SLC38A3

5.14e-041191105GO:0015294
GeneOntologyMolecularFunctionpyrimidine nucleobase transmembrane transporter activity

SLC28A2 SLC29A1

6.20e-0471102GO:0005350
GeneOntologyMolecularFunctionuridylyltransferase activity

UAP1 UAP1L1

6.20e-0471102GO:0070569
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR2 ITPR2 ITPR3

6.53e-04311103GO:0099604
GeneOntologyMolecularFunctionpyrophosphatase activity

PLPP5 MSH2 TRIM23 ABCB1 MDN1 RRAGD SMC3 PLPP4 ABCC2 DNAH8 SNRNP200 RAB5C TBCC

7.14e-0483911013GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

PLPP5 MSH2 TRIM23 ABCB1 MDN1 RRAGD SMC3 PLPP4 ABCC2 DNAH8 SNRNP200 RAB5C TBCC

7.22e-0484011013GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

PLPP5 MSH2 TRIM23 ABCB1 MDN1 RRAGD SMC3 PLPP4 ABCC2 DNAH8 SNRNP200 RAB5C TBCC

7.22e-0484011013GO:0016818
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR2 ITPR2 ITPR3

7.87e-04331103GO:0005217
GeneOntologyMolecularFunctionpyrimidine nucleoside transmembrane transporter activity

SLC28A2 SLC29A1

8.24e-0481102GO:0015214
GeneOntologyMolecularFunctionneutral L-amino acid:sodium symporter activity

SLC38A2 SLC38A3

8.24e-0481102GO:0005295
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC38A2 SLC28A2 SLC29A1 SLC38A3

1.05e-03811104GO:0015370
GeneOntologyMolecularFunctionthyroid hormone transmembrane transporter activity

SLC7A8 SLC7A5

1.06e-0391102GO:0015349
GeneOntologyMolecularFunctionL-glutamine transmembrane transporter activity

SLC38A2 SLC38A3

1.06e-0391102GO:0015186
GeneOntologyMolecularFunctionL-alanine transmembrane transporter activity

SLC7A8 SLC38A3

1.06e-0391102GO:0015180
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC43A2 ABCB1 SLC7A8 SLC38A2 SLC7A5 ABCC2 SLC38A3

1.20e-032931107GO:0008514
GeneOntologyMolecularFunctionpurine nucleobase transmembrane transporter activity

SLC28A2 SLC29A1

1.31e-03101102GO:0005345
GeneOntologyMolecularFunctionnucleoside transmembrane transporter activity

SLC28A2 SLC29A1

1.31e-03101102GO:0005337
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

TMEM94 SLC30A6 SLC38A2 SLC12A9 SLC28A2 SLC29A1 SLC38A3

1.40e-033011107GO:0022853
GeneOntologyMolecularFunctionnucleobase transmembrane transporter activity

SLC28A2 SLC29A1

1.60e-03111102GO:0015205
GeneOntologyMolecularFunctionADP binding

MSH2 NOD2 PRKAG2

2.35e-03481103GO:0043531
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC28A2 SLC38A3

2.62e-03141102GO:1901474
GeneOntologyMolecularFunctionendodeoxyribonuclease activity, producing 5'-phosphomonoesters

EXO1 DNASE1

2.62e-03141102GO:0016888
GeneOntologyMolecularFunctionphosphatidate phosphatase activity

PLPP5 PLPP4

2.62e-03141102GO:0008195
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR2 ITPR3

2.62e-03141102GO:0070679
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCB1 ABCC2

3.01e-03151102GO:0008559
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MSH2 TRIM23 ABCB1 MDN1 RRAGD SMC3 ABCC2 DNAH8 SNRNP200 RAB5C TBCC

3.65e-0377511011GO:0017111
GeneOntologyMolecularFunctionmagnesium ion transmembrane transporter activity

TMEM94 SLC41A2

4.34e-03181102GO:0015095
GeneOntologyMolecularFunctionlipid phosphatase activity

PLPP5 PLPP4

4.84e-03191102GO:0042577
GeneOntologyMolecularFunctioncalcium channel activity

RYR2 ITPR2 ITPR3 PKD1

5.66e-031291104GO:0005262
GeneOntologyMolecularFunctionneurotransmitter transmembrane transporter activity

SLC28A2 SLC29A1

5.90e-03211102GO:0005326
GeneOntologyMolecularFunctionATP-dependent activity

TMEM94 MSH2 MYO5C ABCB1 MDN1 SMC3 ABCC2 DNAH8 SNRNP200

6.87e-036141109GO:0140657
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC38A2 SLC38A3

7.05e-03231102GO:0005283
GeneOntologyMolecularFunctionantiporter activity

SLC30A6 SLC7A8 SLC7A5 SLC38A3

7.17e-031381104GO:0015297
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC6A17 ABCB1 SLC7A8 SLC38A2 SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

1.16e-09871139GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC6A17 ABCB1 SLC7A8 SLC38A2 SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

1.28e-09881139GO:0010232
GeneOntologyBiologicalProcessalanine transport

SLC6A17 SLC7A8 SLC38A2 SLC7A5 SLC38A3

3.65e-08181135GO:0032328
GeneOntologyBiologicalProcessL-leucine transport

SLC43A2 SLC6A17 SLC7A8 SLC7A5

1.75e-07101134GO:0015820
GeneOntologyBiologicalProcessbranched-chain amino acid transport

SLC43A2 SLC6A17 SLC7A8 SLC7A5

8.19e-07141134GO:0015803
GeneOntologyBiologicalProcessneutral amino acid transport

SLC43A2 SLC6A17 SLC7A8 SLC38A2 SLC7A5 SLC38A3

9.31e-07601136GO:0015804
GeneOntologyBiologicalProcessL-leucine import across plasma membrane

SLC43A2 SLC7A8 SLC7A5

1.59e-0651133GO:1903801
GeneOntologyBiologicalProcessL-amino acid transport

SLC43A2 SLC6A17 KMO SLC7A8 SLC38A2 SLC7A5 SLC38A3

2.17e-061081137GO:0015807
GeneOntologyBiologicalProcesscellular response to nutrient levels

KANK2 PHEX SLC38A2 RRAGD MTOR FNIP1 SLC7A5 PRKAG2 SLC38A3

1.42e-052621139GO:0031669
GeneOntologyBiologicalProcessamino acid import across plasma membrane

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

1.64e-05581135GO:0089718
GeneOntologyBiologicalProcessregulation of amino acid transport

SLC43A2 KMO SLC38A2 SLC7A5 SLC38A3

1.94e-05601135GO:0051955
GeneOntologyBiologicalProcessvascular process in circulatory system

TBXAS1 SLC6A17 ABCB1 SLC7A8 SLC38A2 SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

1.98e-0534411310GO:0003018
GeneOntologyBiologicalProcessxenobiotic transport

ABCB1 SLC28A2 SLC7A5 ABCC2 SLC29A1

2.66e-05641135GO:0042908
GeneOntologyBiologicalProcessthyroid hormone transport

SLC7A8 SLC7A5 ABCC2

4.40e-05131133GO:0070327
GeneOntologyBiologicalProcessproline transport

SLC6A17 SLC38A2 SLC7A5

4.40e-05131133GO:0015824
GeneOntologyBiologicalProcessaromatic amino acid transport

SLC7A8 SLC7A5 SLC38A3

4.40e-05131133GO:0015801
GeneOntologyBiologicalProcesscirculatory system process

TBXAS1 ERAP1 SLC6A17 RYR2 ABCB1 SLC7A8 SLC38A2 GUCY1B1 MTOR SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

4.80e-0573311314GO:0003013
GeneOntologyBiologicalProcessregulation of L-leucine import across plasma membrane

SLC43A2 SLC7A5

8.89e-0531132GO:1905532
GeneOntologyBiologicalProcessmethionine transport

SLC43A2 SLC7A5

8.89e-0531132GO:0015821
GeneOntologyBiologicalProcessamino acid transport

SLC43A2 SLC6A17 KMO SLC7A8 SLC38A2 SLC7A5 SLC38A3

1.01e-041951137GO:0006865
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

1.17e-04871135GO:1902475
GeneOntologyBiologicalProcessxenobiotic transmembrane transport

SLC28A2 ABCC2 SLC29A1

1.46e-04191133GO:0006855
GeneOntologyBiologicalProcessorganic cation transport

SLC43A2 SLC6A17 SLC7A8 SLC38A2 SLC7A5 SLC38A3

1.48e-041451136GO:0015695
GeneOntologyBiologicalProcessnegative regulation of lysosome organization

MTOR FNIP1

1.77e-0441132GO:1905672
GeneOntologyBiologicalProcessL-histidine transport

SLC7A5 SLC38A3

1.77e-0441132GO:1902024
GeneOntologyBiologicalProcessinosine transport

SLC28A2 SLC29A1

1.77e-0441132GO:0035340
GeneOntologyBiologicalProcessvaline transport

SLC7A8 SLC7A5

1.77e-0441132GO:0015829
GeneOntologyBiologicalProcessphenylalanine transport

SLC43A2 SLC7A5

1.77e-0441132GO:0015823
GeneOntologyBiologicalProcesshistidine transport

SLC7A5 SLC38A3

1.77e-0441132GO:0015817
GeneOntologyBiologicalProcessregulation of organic acid transport

SLC43A2 KMO SLC38A2 SLC7A5 SLC38A3

2.58e-041031135GO:0032890
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC43A2 ABCB1 SLC7A8 SLC38A2 SLC7A5 SLC38A3

2.80e-041631136GO:1905039
GeneOntologyBiologicalProcessL-glutamine import across plasma membrane

SLC38A2 SLC38A3

2.94e-0451132GO:1903803
GeneOntologyBiologicalProcessregulation of glutamate secretion, neurotransmission

KMO SLC38A2

2.94e-0451132GO:1903294
GeneOntologyBiologicalProcessadenosine transport

SLC28A2 SLC29A1

2.94e-0451132GO:0032238
GeneOntologyBiologicalProcessisoleucine transport

SLC43A2 SLC7A5

2.94e-0451132GO:0015818
GeneOntologyBiologicalProcesspurine nucleoside transmembrane transport

SLC28A2 SLC29A1

2.94e-0451132GO:0015860
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC43A2 ABCB1 SLC7A8 SLC38A2 SLC7A5 SLC38A3

3.18e-041671136GO:1903825
GeneOntologyBiologicalProcesschloride ion homeostasis

TBXAS1 SLC12A9 ABCC2

3.37e-04251133GO:0055064
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC43A2 SLC6A17 KMO ABCB1 SLC7A8 SLC38A2 SLC7A5 ABCC2 SLC38A3

4.29e-044101139GO:0046942
GeneOntologyBiologicalProcessxenobiotic transport across blood-brain barrier

ABCB1 ABCC2

4.40e-0461132GO:1990962
GeneOntologyBiologicalProcesstryptophan transport

SLC7A8 SLC7A5

4.40e-0461132GO:0015827
GeneOntologyBiologicalProcesspyrimidine nucleoside transport

SLC28A2 SLC29A1

4.40e-0461132GO:0015864
GeneOntologyBiologicalProcessuridine transmembrane transport

SLC28A2 SLC29A1

4.40e-0461132GO:0015862
GeneOntologyBiologicalProcessorganic acid transport

SLC43A2 SLC6A17 KMO ABCB1 SLC7A8 SLC38A2 SLC7A5 ABCC2 SLC38A3

4.44e-044121139GO:0015849
GeneOntologyBiologicalProcessmonoatomic anion homeostasis

TBXAS1 SLC12A9 ABCC2

4.75e-04281133GO:0055081
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

5.22e-041201135GO:0003333
GeneOntologyBiologicalProcesscellular response to starvation

SLC38A2 RRAGD MTOR FNIP1 SLC7A5 SLC38A3

5.48e-041851136GO:0009267
GeneOntologyBiologicalProcesspyrimidine nucleobase transport

SLC28A2 SLC29A1

6.14e-0471132GO:0015855
GeneOntologyBiologicalProcessregulation of amine transport

SLC43A2 KMO SLC38A2 SLC7A5 SLC38A3

6.28e-041251135GO:0051952
GeneOntologyBiologicalProcessactin filament bundle assembly

EPS8 KANK2 SHROOM1 RHPN2 MTOR RHPN2P1

6.48e-041911136GO:0051017
GeneOntologyBiologicalProcessactin filament bundle organization

EPS8 KANK2 SHROOM1 RHPN2 MTOR RHPN2P1

7.23e-041951136GO:0061572
GeneOntologyBiologicalProcessimmunoglobulin production involved in immunoglobulin-mediated immune response

SHLD2 MSH2 NOD2 EXO1

7.69e-04751134GO:0002381
GeneOntologyBiologicalProcessnucleoside transmembrane transport

SLC28A2 SLC29A1

8.15e-0481132GO:1901642
GeneOntologyBiologicalProcesspurine nucleobase transmembrane transport

SLC28A2 SLC29A1

8.15e-0481132GO:1904823
GeneOntologyBiologicalProcessregulation of monoatomic anion transmembrane transport

ABCB1 MTOR

8.15e-0481132GO:1903959
GeneOntologyBiologicalProcessresponse to muscle activity

RYR2 SLC38A2 SLC7A5

8.47e-04341133GO:0014850
GeneOntologyBiologicalProcesspositive regulation of amino acid transport

KMO SLC7A5 SLC38A3

8.47e-04341133GO:0051957
GeneOntologyBiologicalProcessamine transport

SLC43A2 KMO SLC38A2 SLC7A5 SLC38A3

9.50e-041371135GO:0015837
GeneOntologyBiologicalProcessglutamate secretion, neurotransmission

KMO SLC38A2

1.04e-0391132GO:0061535
GeneOntologyBiologicalProcessUDP-N-acetylglucosamine biosynthetic process

UAP1 UAP1L1

1.04e-0391132GO:0006048
GeneOntologyBiologicalProcessresponse to nutrient levels

KANK2 NOD2 PHEX SLC38A2 RRAGD MTOR FNIP1 SLC7A5 PRKAG2 SLC38A3

1.11e-0356611310GO:0031667
GeneOntologyCellularComponentexternal side of apical plasma membrane

ABCB1 SLC7A5

3.99e-0461092GO:0098591
GeneOntologyCellularComponentlysosomal membrane

BORCS6 ANKFY1 TLR7 TRIM23 RRAGD MTOR FNIP1 SLC7A5 RAB5C

7.05e-044621099GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

BORCS6 ANKFY1 TLR7 TRIM23 RRAGD MTOR FNIP1 SLC7A5 RAB5C

7.05e-044621099GO:0098852
GeneOntologyCellularComponentintercellular canaliculus

ABCB1 ABCC2

9.47e-0491092GO:0046581
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR2 ITPR3

9.47e-0491092GO:0031095
GeneOntologyCellularComponentapical plasma membrane

ABCB1 ITPR3 SLC7A8 SHROOM1 LMO7 SLC7A5 ABCC2 SLC29A1 SLC38A3

1.02e-034871099GO:0016324
GeneOntologyCellularComponentbrush border

EPS8 ITPR3 SLC38A2 SLC28A2 ABCC2

1.21e-031521095GO:0005903
GeneOntologyCellularComponentvacuolar membrane

BORCS6 ANKFY1 TLR7 TRIM23 RRAGD MTOR FNIP1 SLC7A5 RAB5C

1.35e-035071099GO:0005774
GeneOntologyCellularComponentpinosome

ANKFY1 CX3CR1

1.44e-03111092GO:0044352
GeneOntologyCellularComponentmacropinosome

ANKFY1 CX3CR1

1.44e-03111092GO:0044354
GeneOntologyCellularComponentplatelet dense tubular network

ITPR2 ITPR3

1.44e-03111092GO:0031094
GeneOntologyCellularComponentbasolateral plasma membrane

SLC43A2 NOD2 SLC7A8 PKD1 SLC7A5 SLC29A1 SLC38A3

1.45e-033201097GO:0016323
GeneOntologyCellularComponentsmooth endoplasmic reticulum

FTCD RYR2 DNAJC3

1.78e-03461093GO:0005790
GeneOntologyCellularComponentcell projection membrane

EPS8 PIEZO1 PLXND1 SLC7A8 PKD1 SLC28A2 SLC7A5 ABCC2

1.90e-034311098GO:0031253
HumanPhenoAbnormal neutrophil morphology

FTCD LYST NBAS SF3B1

1.36e-0518444HP:0011992
DomainRIH_assoc-dom

RYR2 ITPR2 ITPR3

4.03e-0661113IPR013662
DomainIns145_P3_rec

RYR2 ITPR2 ITPR3

4.03e-0661113PF08709
DomainRIH_assoc

RYR2 ITPR2 ITPR3

4.03e-0661113PF08454
DomainRIH_dom

RYR2 ITPR2 ITPR3

4.03e-0661113IPR000699
DomainIns145_P3_rcpt

RYR2 ITPR2 ITPR3

4.03e-0661113IPR014821
DomainRyanodine_recept-rel

RYR2 ITPR2 ITPR3

4.03e-0661113IPR015925
Domain-

RYR2 ITPR2 ITPR3

4.03e-06611131.25.10.30
DomainRYDR_ITPR

RYR2 ITPR2 ITPR3

4.03e-0661113PF01365
DomainPH-BEACH_dom

NBEA WDFY4 LYST

1.12e-0581113IPR023362
Domain-

NBEA WDFY4 LYST

1.12e-05811132.30.29.40
DomainPH_BEACH

NBEA WDFY4 LYST

1.12e-0581113PS51783
DomainBEACH

NBEA WDFY4 LYST

1.67e-0591113PS50197
DomainBeach

NBEA WDFY4 LYST

1.67e-0591113PF02138
Domain-

NBEA WDFY4 LYST

1.67e-05911131.10.1540.10
DomainBeach

NBEA WDFY4 LYST

1.67e-0591113SM01026
DomainBEACH_dom

NBEA WDFY4 LYST

1.67e-0591113IPR000409
DomainMIR

RYR2 ITPR2 ITPR3

2.38e-05101113PF02815
DomainMIR_motif

RYR2 ITPR2 ITPR3

2.38e-05101113IPR016093
DomainMIR

RYR2 ITPR2 ITPR3

2.38e-05101113PS50919
DomainMIR

RYR2 ITPR2 ITPR3

2.38e-05101113SM00472
DomainUDPGP

UAP1 UAP1L1

1.05e-0431112PF01704
DomainL_AA_transporter

SLC7A8 SLC7A5

1.05e-0431112IPR004760
DomainInsP3_rcpt-bd

ITPR2 ITPR3

1.05e-0431112IPR000493
DomainUDPGP_fam

UAP1 UAP1L1

1.05e-0431112IPR002618
Domain-

RASA4 RASA4B

1.05e-04311124.10.1130.10
DomainAA-permease/SLC12A_dom

SLC7A8 SLC12A9 SLC7A5

2.90e-04221113IPR004841
DomainAA_permease

SLC7A8 SLC12A9 SLC7A5

2.90e-04221113PF00324
DomainPH_BEACH

NBEA LYST

5.17e-0461112PF14844
DomainBTK

RASA4 RASA4B

1.23e-0391112SM00107
DomainZnf_Btk_motif

RASA4 RASA4B

1.23e-0391112IPR001562
DomainBTK

RASA4 RASA4B

1.23e-0391112PF00779
DomainZF_BTK

RASA4 RASA4B

1.23e-0391112PS51113
DomainP-loop_NTPase

DTYMK MSH2 TRIM23 MYO5C ABCB1 NOD2 MDN1 RRAGD SMC3 ABCC2 DNAH8 SNRNP200 RAB5C

1.57e-0384811113IPR027417
Domain-

DTYMK MSH2 TRIM23 ABCB1 NOD2 MDN1 RRAGD SMC3 ABCC2 DNAH8 SNRNP200 RAB5C

1.60e-03746111123.40.50.300
DomainAAA

ABCB1 MDN1 ABCC2 DNAH8 SNRNP200

1.69e-031441115SM00382
DomainAAA+_ATPase

ABCB1 MDN1 ABCC2 DNAH8 SNRNP200

1.69e-031441115IPR003593
DomainFAD-dep_OxRdtase

L2HGDH KMO

2.22e-03121112IPR006076
DomainDAO

L2HGDH KMO

2.22e-03121112PF01266
DomainAA_permease_2

SLC7A8 SLC7A5

2.62e-03131112PF13520
DomainAA/rel_permease1

SLC7A8 SLC7A5

2.62e-03131112IPR002293
DomainRasGAP

RASA4 RASA4B

3.04e-03141112SM00323
DomainATPase_dyneun-rel_AAA

MDN1 DNAH8

3.04e-03141112IPR011704
DomainRasGAP_CS

RASA4 RASA4B

3.04e-03141112IPR023152
DomainAAA_5

MDN1 DNAH8

3.04e-03141112PF07728
DomainRasGAP

RASA4 RASA4B

3.49e-03151112PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B

3.49e-03151112PS00509
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B

3.49e-03151112PS50018
Domain-

FBXW12 WDR27 NBEA PLXND1 WDFY4 LYST NBAS

3.75e-0333311172.130.10.10
DomainWD40/YVTN_repeat-like_dom

FBXW12 WDR27 NBEA PLXND1 WDFY4 LYST NBAS

3.88e-033351117IPR015943
DomainCARD

CASP2 NOD2

3.98e-03161112SM00114
Domain-

RASA4 RASA4B

3.98e-031611121.10.506.10
DomainARM-type_fold

ARMH1 NBEA WDFY4 LYST ITPR2 SF3B1 MTOR

4.14e-033391117IPR016024
DomainAa_trans

SLC38A2 SLC38A3

4.49e-03171112PF01490
DomainAA_transpt_TM

SLC38A2 SLC38A3

4.49e-03171112IPR013057
Domain-

PLPP5 PLPP4

5.03e-031811121.20.144.10
DomainRasGAP_dom

RASA4 RASA4B

5.03e-03181112IPR001936
DomainacidPPc

PLPP5 PLPP4

5.03e-03181112SM00014
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

9.86e-0732815MM14957
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

1.16e-0633815M188
PathwayKEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY

RRAGD MTOR SLC7A5

6.36e-0514813M47922
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC43A2 SLC7A8 SLC38A2 SLC41A2 SLC28A2 SLC7A5 SLC29A1 SLC38A3

6.53e-05238818MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC43A2 SLC7A8 SLC38A2 SLC41A2 SLC28A2 SLC7A5 SLC29A1 SLC38A3

8.96e-05249818M5988
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR2 ITPR2 ITPR3

1.66e-0419813M47760
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_RSV_ATTACHMENT_AND_ENTRY

FURIN CX3CR1 RAB5C

2.98e-0423813M48234
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR2 ITPR3

3.22e-045812M49000
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

3.88e-04108815M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

4.05e-04109815MM15074
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR2 ITPR3

4.82e-046812M47960
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC43A2 RYR2 ABCB1 SLC7A8 SLC38A2 SLC41A2 FURIN SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

4.85e-046818112MM14985
PathwayREACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK

RRAGD MTOR PRKAG2

6.00e-0429813M19861
PathwayREACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK

RRAGD MTOR PRKAG2

6.00e-0429813MM14980
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY

TLR7 FURIN MED23 CX3CR1 RAB5C

6.29e-04120815M48233
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC6A17 ABCB1 SLC7A8 SLC38A2 SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

7.32e-11105114930280653
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

ABCB1 SLC38A2 SLC28A2 SLC7A5 ABCC2 SLC29A1 SLC38A3

4.00e-1052114726590417
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

BORCS6 NBEA LYST SNX29 SLC30A6 ITPR2 ITPR3 SLC38A2 NBAS FURIN TMEM131L FNIP1 SLC29A1

1.22e-085041141334432599
Pubmed

Amino acid transport across mammalian intestinal and renal epithelia.

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

5.50e-0831114518195088
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

CASP2 MSH2 ABCB1 NOD2 MTOR EXO1 ABCC2 HSD17B3 SLC29A1 CX3CR1

2.59e-073511141020453000
Pubmed

Identification of LAT4, a novel amino acid transporter with system L activity.

SLC43A2 SLC7A8 SLC7A5

3.41e-075114315659399
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR2 ITPR2 ITPR3

6.81e-076114323463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR2 ITPR2 ITPR3

6.81e-076114325966694
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR2 ITPR2 ITPR3

6.81e-076114320519450
Pubmed

Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses.

SLC7A8 MTOR SLC7A5

6.81e-076114336571761
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR2 ITPR2 ITPR3

6.81e-076114316844763
Pubmed

Transport of Iodothyronines by Human L-Type Amino Acid Transporters.

SLC43A2 SLC7A8 SLC7A5

1.19e-067114326305885
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR2 ITPR2 ITPR3

1.19e-067114311860456
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR2 ITPR2 ITPR3

1.90e-068114319033399
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

ANKFY1 RPLP1 ITPR2 MDN1 UBR5 LMO7 RASA4B MED23

2.58e-06262114836880596
Pubmed

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.

SLC30A6 ODR4 TMEM131L DNAJC3 RAB5C

3.80e-0671114536305789
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

LRP1B ITPR2 ITPR3 NBAS SF3B1 MDN1 TMEM131L CNOT1 SNRNP200

4.29e-06375114932788342
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MSH2 MYO5C ITPR3 NBAS MTOR CNOT1 SNRNP200

4.89e-06202114733005030
Pubmed

Defining the membrane proteome of NK cells.

ERAP1 MSH2 PRPF40A ITPR2 ITPR3 NBAS MDN1 UBR5 MTOR OSBPL3 FURIN SLC7A5 DNAJC3 CNOT1 SLC29A1

6.65e-0611681141519946888
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MSH2 PRPF40A MYO5C ABCB1 ITPR2 ITPR3 SF3B1 MDN1 UBR5 SMC3 LMO7 CNOT1 SNRNP200 RAB5C

6.85e-0610241141424711643
Pubmed

Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.

ITPR2 ITPR3

1.07e-05211429065779
Pubmed

LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer.

SLC7A8 MTOR

1.07e-052114230419950
Pubmed

Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin.

ABCB1 ABCC2

1.07e-052114221864659
Pubmed

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCC2 and their impact on drug disposition.

ABCB1 ABCC2

1.07e-052114221039333
Pubmed

Regulation of mTOR by polycystin-1: is polycystic kidney disease a case of futile repair?

MTOR PKD1

1.07e-052114217102641
Pubmed

Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters.

SLC7A8 SLC7A5

1.07e-052114219075510
Pubmed

Overexpression of L-Type Amino Acid Transporter 1 (LAT1) and 2 (LAT2): Novel Markers of Neuroendocrine Tumors.

SLC7A8 SLC7A5

1.07e-052114227224648
Pubmed

Expression and functional characterisation of System L amino acid transporters in the human term placenta.

SLC7A8 SLC7A5

1.07e-052114226050671
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

1.07e-052114211448776
Pubmed

Verapamil inhibits tumor progression of chemotherapy-resistant pancreatic cancer side population cells.

ABCB1 SLC29A1

1.07e-052114227177126
Pubmed

PlexinD1 Deficiency in Lung Interstitial Macrophages Exacerbates House Dust Mite-Induced Allergic Asthma.

PLXND1 CX3CR1

1.07e-052114235110420
Pubmed

ABCC2 haplotype is not associated with drug-resistant epilepsy.

ABCB1 ABCC2

1.07e-052114218416940
Pubmed

PI3K-mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models.

ABCB1 MTOR

1.07e-052114227553832
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

1.07e-05211428081734
Pubmed

Cutting Edge: Direct Sensing of TLR7 Ligands and Type I IFN by the Common Myeloid Progenitor Promotes mTOR/PI3K-Dependent Emergency Myelopoiesis.

TLR7 MTOR

1.07e-052114227566824
Pubmed

Activation of system L heterodimeric amino acid exchangers by intracellular substrates.

SLC7A8 SLC7A5

1.07e-052114211847106
Pubmed

Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response.

ABCB1 CX3CR1

1.07e-052114212545080
Pubmed

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

ABCB1 ABCC2

1.07e-052114216611851
Pubmed

Human exonuclease I interacts with the mismatch repair protein hMSH2.

MSH2 EXO1

1.07e-05211429788596
Pubmed

Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells.

RYR2 ITPR3

1.07e-052114218586264
Pubmed

The Adipose Tissue-Derived Secretome (ADS) in Obesity Uniquely Induces L-Type Amino Acid Transporter 1 (LAT1) and mTOR Signaling in Estrogen-Receptor-Positive Breast Cancer Cells.

MTOR SLC7A5

1.07e-052114234201429
Pubmed

LAT1 and SNAT2 Protein Expression and Membrane Localization of LAT1 Are Not Acutely Altered by Dietary Amino Acids or Resistance Exercise Nor Positively Associated with Leucine or Phenylalanine Incorporation in Human Skeletal Muscle.

SLC38A2 SLC7A5

1.07e-052114234836160
Pubmed

Mitochondrial calcium overload is a key determinant in heart failure.

RYR2 ITPR2

1.07e-052114226217001
Pubmed

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

ITPR2 ITPR3

1.07e-052114215632133
Pubmed

The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice.

ABCB1 ABCC2

1.07e-052114216959944
Pubmed

Cloning and characterization of DPPL1 and DPPL2, representatives of a novel type of mammalian phosphatidate phosphatase.

PLPP5 PLPP4

1.07e-052114217590538
Pubmed

Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex.

ABCB1 ABCC2

1.07e-052114216788565
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

1.07e-052114217496801
Pubmed

A dual PI3 kinase/mTOR inhibitor BEZ235 reverses doxorubicin resistance in ABCB1 overexpressing ovarian and pancreatic cancer cell lines.

ABCB1 MTOR

1.07e-052114232061787
Pubmed

Transport of a neurotoxicant by molecular mimicry: the methylmercury-L-cysteine complex is a substrate for human L-type large neutral amino acid transporter (LAT) 1 and LAT2.

SLC7A8 SLC7A5

1.07e-052114212117417
Pubmed

Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.

ITPR2 ITPR3

1.07e-052114224901844
Pubmed

Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.

ITPR2 ITPR3

1.07e-052114233854148
Pubmed

Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.

RYR2 ITPR2

1.07e-052114228158491
Pubmed

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.

ITPR2 ITPR3

1.07e-052114219528657
Pubmed

The amino acid transporter Slc7a5 regulates the mTOR pathway and is required for granule cell development.

MTOR SLC7A5

1.07e-052114232821949
Pubmed

Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

ITPR2 ITPR3

1.07e-05211428063813
Pubmed

Regulatory mechanisms and pathophysiological significance of IP3 receptors and ryanodine receptors in drug dependence.

RYR2 ITPR3

1.07e-052114224285081
Pubmed

Retinal Microglial Activation Following Topical Application of Intracellular Toll-Like Receptor Ligands.

TLR7 CX3CR1

1.07e-052114226574796
Pubmed

IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

ITPR2 ITPR3

1.07e-052114216195467
Pubmed

Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners.

MSH2 EXO1

1.07e-052114230061603
Pubmed

The potential role of human multidrug resistance protein 1 (MDR1) and multidrug resistance-associated protein 2 (MRP2) in the transport of Huperzine A in vitro.

ABCB1 ABCC2

1.07e-052114231132291
Pubmed

The V249I polymorphism of the CX3CR1 gene is associated with fibrostenotic disease behavior in patients with Crohn's disease.

NOD2 CX3CR1

1.07e-052114218617779
Pubmed

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.

ITPR2 ITPR3

1.07e-052114215713744
Pubmed

Association between the polymorphisms in the ATP-binding cassette genes ABCB1 and ABCC2 and the risk of drug-resistant epilepsy in a Chinese Han population.

ABCB1 ABCC2

1.07e-052114227886333
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

1.07e-052114216041389
Pubmed

Linkage disequilibrium between polymorphisms of ABCB1 and ABCC2 to predict the treatment outcome of Malaysians with complex partial seizures on treatment with carbamazepine mono-therapy at the Kuala Lumpur Hospital.

ABCB1 ABCC2

1.07e-052114223717663
Pubmed

Analysis of candidate genes in occurrence and growth of colorectal adenomas.

MSH2 ABCB1 NOD2

1.22e-0514114319888426
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TMEM94 PIEZO1 PLXND1 LYST ITPR2 ITPR3 NOD2 TDRD3 MDN1 MTOR FURIN TMCC2 PKD1 SLC7A5

1.61e-0511051141435748872
Pubmed

Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome.

SLC7A8 SLC38A2 SLC7A5

1.86e-0516114334890862
Pubmed

Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.

MSH2 ABCB1 ABCC2

1.86e-0516114320368715
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

RPLP1 L2HGDH MSH2 ITPR2 ITPR3 NOD2 NBAS SF3B1 MDN1 UBR5 LMO7 MTOR SLC7A5 PYCR2 CNOT1 SNRNP200

1.93e-0514401141630833792
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

MSH2 SNX29 NBAS TDRD3 LMO7 CENPI CNOT1

2.00e-05251114729778605
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

PIEZO1 KANK2 PRPF40A SNX29 ITPR2 ITPR3 SLC38A2 NBAS SF3B1 MDN1 UBR5 TMEM131L SLC7A5 PYCR2 DNAJC3 SNRNP200

2.85e-0514871141633957083
Pubmed

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.

CASP2 MSH2 ABCB1 NOD2 SLC28A2 EXO1

2.88e-05179114619074885
Pubmed

Polycystin-1 affects cancer cell behaviour and interacts with mTOR and Jak signalling pathways in cancer cell lines.

MTOR PKD1

3.19e-053114231251475
Pubmed

Mismatch repair gene expression in gastroesophageal cancers.

MSH2 EXO1

3.19e-053114226215063
Pubmed

Identification of stereoselective transporters for S-nitroso-L-cysteine: role of LAT1 and LAT2 in biological activity of S-nitrosothiols.

SLC7A8 SLC7A5

3.19e-053114215769744
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR2 ITPR3

3.19e-053114210874040
Pubmed

Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes.

ABCB1 ABCC2

3.19e-053114216505951
Pubmed

Contribution of child ABC-transporter genetics to prenatal MeHg exposure and neurodevelopment.

ABCB1 ABCC2

3.19e-053114235654246
Pubmed

The ABCB1, ABCC2 and RALBP1 polymorphisms are associated with carbamazepine response in epileptic patient: a systematic review.

ABCB1 ABCC2

3.19e-053114235325436
Pubmed

In vivo relevance of Mrp2-mediated biliary excretion of the Amanita mushroom toxin demethylphalloin.

ABCB1 ABCC2

3.19e-053114217707334
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR2 ITPR3

3.19e-053114220395455
Pubmed

Astrocytes contribute to synapse elimination via type 2 inositol 1,4,5-trisphosphate receptor-dependent release of ATP.

ITPR2 CX3CR1

3.19e-053114227067238
Pubmed

Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes.

ABCB1 ABCC2

3.19e-053114217890284
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR2 ITPR3

3.19e-053114217437169
Pubmed

Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells.

NOD2 CX3CR1

3.19e-053114223219392
Pubmed

Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury.

ABCB1 ABCC2

3.19e-053114223896815
Pubmed

Common variants in ABCB1, ABCC2 and ABCG2 genes and clinical outcomes among women with advanced stage ovarian cancer treated with platinum and taxane-based chemotherapy: a Gynecologic Oncology Group study.

ABCB1 ABCC2

3.19e-053114222112610
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

3.19e-053114225637021
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR2 ITPR3

3.19e-053114218547250
Pubmed

Fibroblast-like synoviocyte migration is enhanced by IL-17-mediated overexpression of L-type amino acid transporter 1 (LAT1) via the mTOR/4E-BP1 pathway.

MTOR SLC7A5

3.19e-053114229198077
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR2 ITPR3

3.19e-053114236350267
Pubmed

The versatility and universality of calcium signalling.

ITPR2 ITPR3

3.19e-053114211413485
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

3.19e-053114226009177
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR2 ITPR3

3.19e-05311421693919
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR2 ITPR3

3.19e-053114223955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR2 ITPR3

3.19e-053114231979185
Pubmed

Renal Dnase1 expression is regulated by FGF23 but loss of Dnase1 does not alter renal phosphate handling.

PHEX DNASE1

3.19e-053114233731726
Pubmed

Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome.

MSH2 EXO1

3.19e-053114212414623
Cytoband7q34-q35

TBXAS1 CASP2

1.83e-05311427q34-q35
CytobandEnsembl 112 genes in cytogenetic band chr1q43

KMO RYR2 EXO1

5.07e-04621143chr1q43
GeneFamilySolute carriers

SLC43A2 SLC6A17 SLC30A6 SLC7A8 SLC38A2 SLC41A2 SLC12A9 SLC28A2 SLC7A5 SLC29A1 SLC38A3

8.64e-073957711752
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEA WDFY4 LYST

6.13e-0697731230
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR2 ITPR3

5.36e-053772297
GeneFamilyPhospholipid phosphatases

PLPP5 PLPP4

3.71e-0477721067
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

7.88e-0410772830
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC34 TTC31 TTC22 DNAJC3

1.47e-03115774769
GeneFamilyWD repeat domain containing

FBXW12 WDR27 NBEA WDFY4 LYST

5.20e-03262775362
CoexpressionAtlasB cells, B.MZ.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23- CD21.35+, Spleen, avg-1

TLR7 PLXND1 WDFY4 SNX29 KMO ABCB1 ITPR3 SLC41A2 SLC28A2 TMEM131L

5.97e-0632610710GSM538210_500
CoexpressionAtlasB cells, B.MZ.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23- CD21/35+, Spleen, avg-2

TLR7 PLXND1 WDFY4 SNX29 KMO ABCB1 ITPR3 SLC41A2 SLC28A2 TMEM131L

8.85e-0634110710GSM538211_500
CoexpressionAtlasMyeloid Cells, DC.8-4-11b+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1

EPS8 TLR7 PLXND1 WDFY4 LYST KMO ABCB1 RASA4 TMEM131L CX3CR1

3.13e-0539510710GSM538265_500
CoexpressionAtlasMyeloid Cells, DC.8-4-11b+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-2

EPS8 TLR7 PLXND1 WDFY4 LYST KMO ABCB1 RASA4 TMEM131L

1.21e-043761079GSM538266_500
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_500

FBXW12 TRIM23 RYR2 ABCB1 PHEX RHPN2 LMO7 FNIP1 DNAH8

1.29e-043791079gudmap_developingGonad_P2_ovary_500
CoexpressionAtlasMyeloid Cells, DC.4+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1

EPS8 TLR7 PLXND1 WDFY4 LYST KMO ABCB1 RASA4 TMEM131L

1.37e-043821079GSM538248_500
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#4_top-relative-expression-ranked_500

FBXW12 ABCB1 PHEX RHPN2 LMO7 DNAH8

1.50e-041581076gudmap_developingGonad_P2_ovary_500_k4
CoexpressionAtlasMyeloid Cells, DC.4+.Sp, CD11b CD11c CD45 CD8a CD4, Spleen, avg-3

EPS8 TLR7 PLXND1 WDFY4 LYST KMO ABCB1 RASA4 TMEM131L

1.63e-043911079GSM538249_500
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ANKFY1 ITPR2 ANKRD44 SLC38A2 NBAS RASA4 OSBPL3 TMEM131L

2.59e-0818611388571956890fc9894d766ba294a28e376b4aba428
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

ANKFY1 ANKRD44 SLC38A2 NBAS RASA4 OSBPL3 TMEM131L

4.74e-071851137a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ANKFY1 LYST ANKRD44 NBAS OSBPL3 TMEM131L SLC7A5

5.88e-0719111379454f642c3621370fa23640b631301346b300950
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBXAS1 TLR7 WDFY4 NOD2 ANKRD44 TVP23A CX3CR1

6.31e-0719311373e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 KMO SLC7A8 CX3CR1

4.50e-0616811368ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCellfacs-Heart-RV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 KMO SLC7A8 CX3CR1

4.50e-061681136c1a5f4f4d32a1f8583048db709a7037cc9357ad8
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 KMO SLC7A8 CX3CR1

4.50e-061681136a405f0de70293f68b4e000c1fc8a9ad33d56539a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TBXAS1 TLR7 WDFY4 NOD2 TVP23A CX3CR1

5.15e-061721136f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 KMO SLC7A8 CX3CR1

5.51e-06174113654166a0faf748cccb6406c2c268e1e6e21caf6d0
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 KMO SLC7A8 CX3CR1

5.51e-061741136dc8a238ec1d954bec0f8eb67c04a61734c96f5b5
ToppCellfacs-Heart-LV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 KMO SLC7A8 CX3CR1

5.69e-0617511365d106ef542b97f97aeb19179e3f72963ead1e82a
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 EPS8 SLC7A8 SLC12A9 RASA4 CX3CR1

5.69e-061751136d983e80eeb11f341c564ea684e2b0b585a90ae58
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TBXAS1 TLR7 WDFY4 NOD2 TVP23A CX3CR1

5.88e-061761136926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

SLC43A2 EPS8 UAP1 ITPR2 LMO7 PLPP4

7.35e-0618311365c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

MSH2 FTCD ITPR2 RHPN2 LMO7 ABCC2

9.95e-061931136503a979328c68b096680b71359a26f02fafdff35
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

TBXAS1 SLC43A2 PLXND1 SNX29 SLC7A8 PRKAG2

1.02e-051941136800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

TBXAS1 WDFY4 SNX29 KMO ITPR2 PRKAG2

1.06e-051951136c172c5599379c29123340621a36bfb1fc90c2115
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TBXAS1 TLR7 WDFY4 NOD2 ANKRD44 CX3CR1

1.12e-05197113657dafb3047745a44b2345b8036e159c3641d496e
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

EPS8 MYO5C ABCB1 MDN1 RASA4 RASA4B

1.15e-051981136b8bd1ba268480f54451648e01631b615a3401144
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TBXAS1 TLR7 WDFY4 NOD2 ANKRD44 CX3CR1

1.15e-051981136623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBXAS1 PLXND1 WDFY4 KMO CX3CR1 RAB5C

1.18e-05199113654167894a16e975d0541cbe3e515bcfa183044f6
ToppCellMild/Remission-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PLPP5 SNX29 KMO LMO7 TMEM131L

3.80e-051481135dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCellE16.5-samps-Myeloid-Fetal_macrophage-macrophage_-_intermediate_-_unactivated|E16.5-samps / Age Group, Lineage, Cell class and subclass

TLR7 NOD2 SLC7A8 OSBPL3 CX3CR1

4.05e-05150113560fdd266aaca1b589b9a77465a4a7fad4921339a
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

RPLP1 ABCB1 RASA4B ABCC2 HSD17B3

4.59e-051541135afdc385397c7b13c9348eeef95f109f2363057ae
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 SLC7A8 RASA4 EXO1 CX3CR1

4.73e-05155113593bfcf5c12cbb61a1e0444312afd2aa411a8bf50
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PLPP5 TMEM94 ARMH1 WDFY4 TMEM131L

4.73e-0515511350a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

UAP1 ABCB1 GUCY1B1 TMCC2 CX3CR1

5.03e-051571135542944030cd9b3f3559e64f9f6598694d74003c0
ToppCelldroplet-Heart-nan-3m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

6.19e-051641135df9fe446c1a43100048e11c01bf009bec3414dcf
ToppCellC_02|World / shred on cell type and cluster

ABCB1 SLC38A2 SLC28A2 ABCC2 DNASE1

6.37e-051651135a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TBXAS1 SLC7A8 RASA4B UAP1L1 CX3CR1

6.37e-0516511358d3d5860a4785c4908160ae5fcb421ee80bd78ce
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TBXAS1 SLC7A8 RASA4B UAP1L1 CX3CR1

6.37e-05165113517ee6f269ed8d378465cf00ca59d48d8b106808e
ToppCellNS-critical-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMEM221 TLR7 WDFY4 PHEX SLC7A5

6.37e-05165113517d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCellThalamus-Hematopoietic|Thalamus / BrainAtlas - Mouse McCarroll V32

TBXAS1 TMEM221 TLR7 WDFY4 CX3CR1

6.55e-05166113576d60ac7ac5d1eaf530f0c741d9c48e0bd58396b
ToppCelldroplet-Heart-nan-3m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

6.74e-05167113547447bcf184b1ad24ef17e135199fe7cd1d73c02
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHLD2 TMEM94 TLR7 SLC7A5 CX3CR1

6.93e-0516811356fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

TLR7 WDFY4 PHEX SLC41A2 SLC7A5

6.93e-051681135dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCelldroplet-Heart-nan-3m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

6.93e-051681135a4eebc78babb9b5ef33065b0642793820195a613
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHLD2 TMEM94 TLR7 SLC7A5 CX3CR1

6.93e-051681135794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHLD2 TMEM94 TLR7 SLC7A5 CX3CR1

6.93e-0516811351e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 WDFY4 SLC7A8 CX3CR1

7.13e-0516911353296305dc4fa40c466dab56aab4eac302ae3d7f7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC43A2 EPS8 ITPR2 ANKRD44 PLPP4

7.13e-0516911354b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC43A2 EPS8 ITPR2 ANKRD44 PLPP4

7.13e-051691135a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBXAS1 PLXND1 WDFY4 KMO ITPR2

7.33e-0517011359ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 EPS8 RPLP1 WDFY4 KMO

7.33e-0517011359e94fa0d05abed3438b28296a293767096d517d6
ToppCelldroplet-Heart-nan-18m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

7.33e-0517011357077eaf68ac859f63d6581d26a95c20d6a04bd28
ToppCelldroplet-Heart-nan-18m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

7.54e-0517111352594ba8236a69461d9786ffcd882c39d0c9d5788
ToppCelldroplet-Heart-nan-18m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

7.54e-05171113579b806194df645cccd357520eb6801ab1e93b3c5
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C12orf56 SLC6A17 ARMH1 RRAGD TTC22

7.96e-051731135a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 EPS8 TLR7 SLC7A8

7.96e-051731135a664dbd7fb55b1c4309fa5f9425bc83924dac545
ToppCellIonocyte-iono-2|World / Class top

SLC43A2 ITPR2 SLC41A2 RRAGD RASA4

7.96e-051731135e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 EPS8 TLR7 SLC7A8

7.96e-051731135054f64462b648ba6b4b28b48c716dc01b2ddd790
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 EPS8 TLR7 SLC7A8

7.96e-0517311359a8fec9a08bb61456a4ea43ae1316bd3e197a773
ToppCellfacs-Heart-LA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

8.18e-05174113530c083fe4711735e83dccfd00fcd746ae673d353
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

8.18e-05174113546d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 SLC43A2 TLR7 SLC7A8 CX3CR1

8.18e-0517411351802a52552256d1e25d8b328ba62dcfe41671900
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC6A17 ARMH1 PLXND1 SLC7A8 MDN1

8.18e-051741135d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TBXAS1 EPS8 PLXND1 WDFY4 KMO

8.18e-051741135c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC43A2 EPS8 UAP1 ITPR2 PLPP4

8.18e-0517411355f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCelldroplet-Lung-nan-21m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C12orf56 ARMH1 MYO5C RRAGD TTC22

8.40e-0517511353ed22ea41810e73c02db4f2d03745e4ce7e43bb1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC43A2 EPS8 UAP1 ITPR2 PLPP4

8.40e-05175113577c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR7 SLC38A2 LGI3 SLC7A5 CX3CR1

8.40e-0517511351ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCelldroplet-Lung-nan-21m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C12orf56 ARMH1 MYO5C RRAGD TTC22

8.40e-0517511358fb1e5f6aa68274adf322401db8c7b80e8c554d7
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPS8 WDFY4 KMO CENPI EXO1

8.63e-051761135581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

WDFY4 SNX29 ANKRD44 TMEM131L DNAH8

8.63e-051761135d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C12orf56 ARMH1 MYO5C RRAGD TTC22

8.87e-051771135d947ba38db1772fc5fdcdc211f7511c4aa699dee
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C12orf56 ARMH1 MYO5C RRAGD TTC22

8.87e-051771135d5640f0097878f0dac671e51dc51310278bb2682
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLPP5 NBEA ABCB1 RHPN2 DNAJC3

9.10e-051781135b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCellerythropoietic-Erythrocyte|erythropoietic / Lineage and Cell class

AHSP TMCC2

9.32e-05611322e2f58fb39133c7195e8bedbdc56656803e92838
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM221 PLXND1 SLC7A8 MED23 SFT2D2

9.35e-0517911352c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMH1 WDFY4 PHEX SLC41A2 SLC7A5

9.35e-0517911354808469096cd6bec2bdfcf4fc55aa324757600c3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM221 PLXND1 SLC7A8 MED23 SFT2D2

9.35e-0517911356eb84fe9691ad40127b2d1f1c672428333c8fab4
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBXAS1 SLC7A8 RASA4 UAP1L1 CX3CR1

9.35e-051791135fae869fb0a91428481bf8a9c111dcc639e2b4278
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMH1 WDFY4 PHEX SLC41A2 SLC7A5

9.35e-0517911354d55718c6afd8a038d93cc77b9b08171dab9976f
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM221 TLR7 SNX29 KMO SLC41A2

9.60e-051801135df60970520fba2ac0639faa54096766d07418ca4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B RRAGD OSBPL3 SLC7A5 DNASE1

9.60e-051801135eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B RRAGD OSBPL3 SLC7A5 DNASE1

9.60e-051801135a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FTCD SNX29 KMO RYR2 SLC7A8

9.85e-051811135c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC43A2 EPS8 UAP1 ITPR2 LMO7

9.85e-05181113530729f0364f719c044712a51453e22dc2c1a232b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B LYST MYO5C ITPR3 OSBPL3

1.01e-041821135a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell(4)_B_cells-(4)_B_mantle|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

DONSON PLPP5 LYST SNX29 ABCB1

1.04e-04183113521b7fb6482eb1d5d31a4029e47e0992e8ddc8e2c
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

TBXAS1 WDFY4 ANKRD44 SLC41A2 TVP23A

1.04e-041831135b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

UAP1 PIEZO1 OSBPL3 SLC7A5 TTC22

1.06e-041841135af6522586d012e91241f3e06c60f9d1881e95646
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCB1 ITPR3 RHPN2 FNIP1 MED23

1.09e-04185113587151ab95530e70d61328b336518df58db584acb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC43A2 EPS8 UAP1 RPLP1 PLPP4

1.09e-0418511359438097e94219c1db922b8507e3a29106d32a923
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLR7 WDFY4 KMO PHEX SLC7A5

1.12e-0418611350096a61b1841784c913752b4f3639200446cc02c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 UAP1 ITPR2 LMO7 OSBPL3

1.12e-041861135a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLR7 WDFY4 KMO PHEX SLC7A5

1.12e-0418611356345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

TLR7 WDFY4 PHEX SLC41A2 SLC7A5

1.12e-041861135916f2aeea4989ba7a29e071e348a51010f010223
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLR7 WDFY4 KMO PHEX SLC7A5

1.12e-0418611359e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC43A2 FTCD SNX29 SLC7A8 ABCC2

1.12e-0418611355784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellhealthy_donor-Lymphocytic-Dendritic-pDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

TLR7 WDFY4 PHEX SLC41A2 SLC7A5

1.12e-04186113545f66619e45d590c7365a51782d4ac46b7d31fde
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B RRAGD OSBPL3 SLC7A5 DNASE1

1.15e-04187113585e58a312fc325e4063a2d250666b99b8f99beb6
ToppCellmyeloid-pDC|World / Lineage and Cell class

TLR7 WDFY4 PHEX SLC7A5 SFT2D2

1.24e-04190113588c42779ce2f817d28e672d83f3f1158581edf73
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

WDFY4 SNX29 KMO ANKRD44 TMEM131L

1.24e-041901135424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RPLP1 RRAGD LMO7 OSBPL3 SLC7A5

1.27e-041911135f631749ef1f2270133664cf5eb4cf545a8482bd3
ToppCellCOVID-19_Moderate-pDC|World / disease group, cell group and cell class

TLR7 WDFY4 PHEX SLC41A2 SLC7A5

1.27e-04191113593adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

WDFY4 SNX29 KMO ANKRD44 TMEM131L

1.27e-04191113584452125d1b5b76974e3f9126f611eff16d45c25
ToppCellInfluenza_Severe-Non-classical_Monocyte|Influenza_Severe / Disease group and Cell class

TBXAS1 EPS8 GUCY1B1 SLC29A1 CX3CR1

1.27e-041911135197edf6feb1cfc71d88e532d74f77305a42a3486
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1B RRAGD LMO7 OSBPL3 DNASE1

1.30e-041921135562df5e87038c500dd3a003fe5374cb31946b145
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITPR2 RRAGD OSBPL3 SLC7A5 DNASE1

1.30e-041921135ee27d27e3d269764dbe8711d0b37ff9331a298a9
DrugMeAIB

SLC43A2 SLC7A8 SLC38A2 SLC7A5 SLC38A3

1.69e-06421095CID000095739
DrugAmino Acids, Peptides, and Proteins

SLC43A2 ABCB1 SLC7A8 MTOR SLC7A5

2.40e-06451095ctd:D000602
Drug2,3-dibromopropyl-2,4,6-tribromophenyl ether

SLC43A2 SLC7A8 SLC7A5 HSD17B3

3.40e-06221094ctd:C547124
Drugasparagine

SLC7A8 SLC38A2 ARSL SLC7A5 SLC38A3

5.48e-06531095CID000000236
DrugAC1L92T5

MSH2 LYST ABCB1 SLC29A1 SLC38A3

7.21e-06561095CID000412123
Drugallyl 2,4,6-tribromophenyl ether

SLC43A2 SLC7A8 SLC7A5

1.25e-05101093ctd:C000610085
Drugenkephalin-Leu, Ala(2)-melphalan methyl ester-

ABCB1 ABCC2

2.27e-0521092ctd:C040240
Drugadenophostin A

ITPR2 ITPR3

2.27e-0521092ctd:C085029
Drugbenzoylmesaconine

ABCB1 ABCC2

2.27e-0521092ctd:C085283
Drugbenzoylaconine

ABCB1 ABCC2

2.27e-0521092ctd:C047307
DrugCAS 298-57-7

RYR2 ITPR3 NOD2 PKD1 HRH4

2.66e-05731095CID000002761
DrugPrestwick_523

DTYMK MSH2 SLC28A2 SLC29A1

3.59e-05391094CID000003687
Drugprochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A

BORCS6 SNX29 TRIM23 NOD2 SLC7A8 TTC22 ABCC2

4.47e-0519610976174_UP
DrugChlorpropamide [94-20-2]; Down 200; 14.4uM; PC3; HT_HG-U133A

PIEZO1 L2HGDH NBAS TDRD3 GUCY1B1 TTC31 SLC29A1

4.62e-0519710976291_DN
DrugGlipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A

BORCS6 ERAP1 CASP2 LYST TRIM23 ITPR2 TDRD3

4.62e-0519710971508_DN
DrugMethiazole; Up 200; 15uM; PC3; HT_HG-U133A

ERAP1 ITPR2 PHEX SLC7A8 RRAGD NEK11 CX3CR1

4.62e-0519710974532_UP
DrugMuramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; HL60; HT_HG-U133A

ANKFY1 TMEM94 PIEZO1 L2HGDH LYST TRIM23 OSBPL3

4.77e-0519810971326_DN
Drugprulifloxacin

ABCB1 ABCC2

6.79e-0531092ctd:C074191
Drugisopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate

ABCB1 ABCC2

6.79e-0531092ctd:C000603302
Drugdehydroheliotridine

SMC3 SLC38A3

6.79e-0531092CID000033501
Drugbenzoylhypaconine

ABCB1 ABCC2

6.79e-0531092ctd:C479202
Drugmesaconitine

ABCB1 ABCC2

6.79e-0531092ctd:C019470
Drugleucinol

SLC7A8 MTOR SLC7A5

6.91e-05171093CID000079030
DiseaseColorectal Carcinoma

DONSON MSH2 ABCB1 RHPN2 LMO7 EXO1 BPIFB2 ABCC2 DNAH8 SNRNP200 SLC29A1 RAB5C

9.45e-0670210712C0009402
Diseaseend stage renal disease (implicated_via_orthology)

ABCB1 MTOR ABCC2

5.05e-05201073DOID:783 (implicated_via_orthology)
Diseaseautosomal dominant polycystic kidney disease (is_implicated_in)

MTOR PKD1

7.78e-0541072DOID:898 (is_implicated_in)
DiseaseChediak-Higashi syndrome (implicated_via_orthology)

WDFY4 LYST

7.78e-0541072DOID:2935 (implicated_via_orthology)
Diseasedisease recurrence, unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

TTC34 LRP1B PLPP4

2.34e-04331073EFO_0003761, EFO_0004952, EFO_0008343, MONDO_0004985, MONDO_0005090
Diseasecolon cancer (is_implicated_in)

MSH2 LRP1B SLC7A5

3.03e-04361073DOID:219 (is_implicated_in)
Diseasevisual epilepsy (biomarker_via_orthology)

MSH2 ABCB1 SLC38A2 SLC38A3

3.29e-04901074DOID:11832 (biomarker_via_orthology)
Diseasetemporal lobe epilepsy (implicated_via_orthology)

ABCB1 MTOR

4.61e-0491072DOID:3328 (implicated_via_orthology)
Diseasefamilial Mediterranean fever (is_implicated_in)

ABCB1 NOD2

4.61e-0491072DOID:2987 (is_implicated_in)
Diseasehepatocellular carcinoma (is_implicated_in)

LRP1B ABCB1 SF3B1 SMC3 SLC7A5

5.27e-041811075DOID:684 (is_implicated_in)
DiseaseColorectal Neoplasms

DONSON MSH2 ABCB1 RHPN2 EXO1 ABCC2

5.30e-042771076C0009404
Diseasehemolysis

PIEZO1 GALNT8 MINDY4

6.69e-04471073EFO_0009473
Diseaseinvasive ductal carcinoma (is_implicated_in)

ABCB1 UBR5

7.01e-04111072DOID:3008 (is_implicated_in)
Diseaselung adenocarcinoma (is_implicated_in)

MSH2 LRP1B UBR5

7.57e-04491073DOID:3910 (is_implicated_in)
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR2 ITPR3

8.40e-04121072DOID:1441 (implicated_via_orthology)
Diseasehypertension

ERAP1 MSH2 SLC12A9 GUCY1B1 FURIN PRKAG2

9.06e-043071076EFO_0000537
DiseaseIntellectual Disability

TMEM94 CASP2 L2HGDH NBEA MTOR MED23 PYCR2

1.24e-034471077C3714756
DiseaseGlobal developmental delay

TMEM94 NBEA NBAS CNOT1

1.42e-031331074C0557874
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

UBR5 MTOR

1.51e-03161072C0334634
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

MTOR PKD1

1.51e-03161072DOID:0110861 (implicated_via_orthology)
Diseaselung non-small cell carcinoma (is_implicated_in)

MSH2 LRP1B ABCB1 ABCC2

1.67e-031391074DOID:3908 (is_implicated_in)
Diseaseglomerulonephritis (implicated_via_orthology)

TBXAS1 CX3CR1

1.71e-03171072DOID:2921 (implicated_via_orthology)
Diseasehair colour measurement

PIEZO1 L2HGDH LYST SLC38A2 SLC12A9 TMCC2 SLC7A5 BPIFB2

1.82e-036151078EFO_0007822
DiseaseDermatitis, Allergic Contact

TLR7 KMO SLC7A5

1.88e-03671073C0162820
Diseasesyndrome (implicated_via_orthology)

DONSON CNOT1

1.92e-03181072DOID:225 (implicated_via_orthology)
Diseasesusceptibility to mononucleosis measurement

RYR2 MDN1 DNAH8

2.04e-03691073EFO_0008403
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

MSH2 EXO1

2.14e-03191072C2936783
Diseaselung cancer (is_implicated_in)

MSH2 LRP1B NOD2

2.49e-03741073DOID:1324 (is_implicated_in)
Diseasepsychotic symptoms

MSH2 WDFY4 SNX29

2.49e-03741073EFO_0005940
Diseasechronic myeloid leukemia (is_implicated_in)

ABCB1 ABCC2

2.62e-03211072DOID:8552 (is_implicated_in)
Diseasestatus epilepticus (implicated_via_orthology)

MTOR CX3CR1

2.62e-03211072DOID:1824 (implicated_via_orthology)
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

LRP1B NBAS PLPP4

2.69e-03761073EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
Diseasecholangiocarcinoma (is_implicated_in)

SLC7A5 ABCC2

2.87e-03221072DOID:4947 (is_implicated_in)
Diseaselymphocyte count, response to vaccine

NBAS OSBPL3

2.87e-03221072EFO_0004587, EFO_0004645

Protein segments in the cluster

PeptideGeneStartEntry
LQSLKLLLQVSFQGA

nan

236

Q6ZR03
TLQVKKAFFALVANG

PRKAG2

286

Q9UGJ0
FQVLALVALTLVAGK

ARSL

201

P51690
ISAGLKEFSVLLNQQ

AHSP

11

Q9NZD4
FLQQAAAAKAIGVLA

ARMH1

296

Q6PIY5
LVGNLLVVFALTNSK

CX3CR1

46

P49238
KLLAAGQLADALSQF

DNAJC3

46

Q13217
VATNLLKLFLGQGLA

RASA4

306

O43374
VATNLLKLFLGQGLA

RASA4B

306

C9J798
NIVIALAGNKADLAS

RAB5C

126

P51148
LGAANLCNKIVFLVS

ITPR2

2311

Q14571
GALNLTNKIVFVVSF

ITPR3

2286

Q14573
VQDIFTAGKLLALAL

SLC7A8

186

Q9UHI5
KAITANISIGAAFLL

ABCB1

291

P08183
TFLIKNGAFVNAATL

ANKFY1

306

Q9P2R3
KQLAFESLAVIGNAL

MDN1

5401

Q9NU22
TLLKQGLNNVIAIDF

LRP1B

3036

Q9NZR2
IIINSGLIKLASQNF

L2HGDH

351

Q9H9P8
NALSVLIFIALALNG

SLC43A2

141

Q8N370
AAKVLALLNTANNLV

HECTD2

316

Q5U5R9
NNAFQLVSIGKLSIE

ERAP1

641

Q9NZ08
FLDLFGLLQVSQVNK

FBXW12

16

Q6X9E4
FLGTVNGRLLKINLN

PLXND1

486

Q9Y4D7
FVVFLKALSGNAVLI

OR2T5

36

Q6IEZ7
EFILLGLSKSQNLQI

OR4K13

11

Q8NH42
SNINLQGKAFVSGLL

ODR4

16

Q5SWX8
LAVANAELGKAQALL

DNAH8

3301

Q96JB1
LLQFISGSIQKNALA

MED23

376

Q9ULK4
AFAGSNFLSIVLKIV

NEK11

231

Q8NG66
VQDAFAAAKLLALAL

SLC7A5

196

Q01650
LNLKAFENLLGQALT

LMO7

191

Q8WWI1
LAKQVFVGFLLILAA

ABCC2

66

Q92887
LVAAASKVLNLNAGE

GUCY1B1

51

Q02153
VNLLLAKGANINAFD

ANKRD44

156

Q8N8A2
LFAKALANVNIGSLI

RPLP1

46

P05386
HLVLASNGKLLAAVQ

NBAS

91

A2RRP1
KEAFLAVSLALALNG

PLPP4

81

Q5VZY2
FVVFLKALSGNAVLI

OR2T29

36

Q8NH02
VLENAFNGTLVIKLN

PCDHA13

251

Q9Y5I0
TLDAGNIKLAFNSLL

PRPF40A

711

O75400
VINKGLFFLGSLIAI

KMO

421

O15229
FVANNLQLKIRLSGA

BORCS6

216

Q96GS4
LLQGAVSLKIAAFNI

DNASE1

16

P24855
VNLLLVFSSKGTLQN

GALNT8

21

Q9NY28
ASKNQFLPALITAVL

FNIP1

446

Q8TF40
TLVLLAADAQGQKVF

FURIN

16

P09958
GFLLLTKLNSIIDQA

LYST

51

Q99698
VLVKGINTFTLLNFL

DONSON

401

Q9NYP3
TVLQLFRLGNINAKA

KANK2

721

Q63ZY3
SLGVLNGAQLFSLNK

EPS8

746

Q12929
ILLNIALSGKFGNAV

CENPI

111

Q92674
QKGLILNISSGIALF

HSD17B3

176

P37058
NLLNIFISNSGIEKA

RRAGD

246

Q9NQL2
AKDIGFNVAVLLTNL

RYR2

4091

Q92736
KLDIAAVRALNLFQG

MSH2

301

P43246
AKVGSFSQNVELLNL

CASP2

76

P42575
FLIAFNINLLGTKEQ

FTCD

181

O95954
QVIGLKNALSSALAQ

OSBPL3

376

Q9H4L5
AASLLFLLLVKAAQQ

PKD1

3991

P98161
LGLTQNAEAQKLLFA

OR4C5

36

Q8NGB2
IVSIKLLAAIQLFGA

MTOR

1091

P42345
LGNALVILAFVVDKN

HRH4

31

Q9H3N8
SGGQKSLVALALIFA

SMC3

1116

Q9UQE7
GKLAAALAITLQNIG

SLC38A3

141

Q99624
AGLNSILFAINIDNK

SNX29

166

Q8TEQ0
LSGIVDIKNGFLLLN

TDRD3

36

Q9H7E2
NKGLALIFCILQSLA

SFT2D2

121

O95562
NANARALLGKFINVI

TMCC2

636

O75069
AAAVNLLLGVFQVLL

TMEM131L

16

A2VDJ0
SIQKNAGLAFIELIN

NBEA

1951

Q8NFP9
LAFPITASQKIALNA

SHLD2

666

Q86V20
ALLAGKAAVLAQQRN

SHROOM1

791

Q2M3G4
LALKQVQATVVGFLA

SLC41A2

241

Q96JW4
LAIQLGAQALLGAAK

PYCR2

201

Q96C36
NLLLEKASVLFNTGA

RHPN2

211

Q8IUC4
KLSVAQLALGAQILS

EEF1AKMT4

216

P0DPD7
IALQIALGNKDINTF

EXO1

321

Q9UQ84
AIGLATNVAANLIAF

SLC28A2

416

O43868
TNVAANLIAFLAVLA

SLC28A2

421

O43868
KIVLINSFGAILQGS

SLC29A1

146

Q99808
QQLFDSALLLLQKAG

BPIFB2

261

Q8N4F0
NFFLVLGIDAAQKNL

CLBA1

221

Q96F83
NTLAAKKGALFNLLV

C12orf56

431

Q8IXR9
LSKVQEVIFGLALLN

CNOT1

121

A5YKK6
LNGFFNKLIRNVIAL

TBXAS1

251

P24557
VNLLLTGKAVSNVFN

MINDY4

606

Q4G0A6
DLATVKANGLAAFLL

NOD2

186

Q9HC29
ANGLLSAQKLTAALI

TMEM94

1226

Q12767
QKIGALFFLLSGVLV

SLC38A2

471

Q96QD8
LNVQNGVLKSLSFLF

SF3B1

1141

O75533
QLVLLAGKLNTLAAV

SLC12A9

406

Q9BXP2
ALALNGVFTNTIKLI

PLPP5

96

Q8NEB5
LQTLAIAAFPLGAQK

WDFY4

1821

Q6ZS81
ISLNKVAVLLLAGGQ

UAP1L1

101

Q3KQV9
ILFLVSQGLLSLQAK

PHEX

36

P78562
LQGLQKLINDSVFFL

TBCC

91

Q15814
NLLLEKASVLFNTGA

RHPN2P1

126

A8MT19
VLDLGTNFIKIANLS

TLR7

401

Q9NYK1
FQISQNKVAVLLLAG

UAP1

96

Q16222
VLLQAFISQLKLEGF

SNRNP200

1061

O75643
ASTVLAQLGALFILK

SLC30A6

106

Q6NXT4
AVLAALGAQLLFQLQ

TMEM221

21

A6NGB7
LATLVVFAVLGFKAN

SLC6A17

346

Q9H1V8
TVLGKLAFQVALVLA

PIEZO1

2026

Q92508
LALVVAGISLQAANL

TVP23A

151

A6NH52
QLATATLDGKLQLFL

WDR27

811

A2RRH5
ALLLIFANKQDVAGA

TRIM23

506

P36406
AFAQALKLAPSLAQN

TTC34

486

A8MYJ7
ALNQALVFLAKAGES

TTC22

411

Q5TAA0
TSVNIQELLLGKNFL

ZNF805

581

Q5CZA5
FLGLTNEKIVLLSAN

UBR5

416

O95071
GLLAAALQQSQELAK

TTC31

296

Q49AM3
LESLFVLLSNGAVKQ

TRAV39

61

A0A0B4J263
LFLQLQLADAAKRGA

DTYMK

131

P23919
QFLLLNSNKFTLIGD

LGI3

91

Q8N145
VKQLFFLIGAVTLNS

MYO5C

1576

Q9NQX4