Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	methyl-CpG binding	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	6.40e-07	31	108	5	GO:0008327
GeneOntologyMolecularFunction	alpha-tocopherol omega-hydroxylase activity	CYP4F2 CYP4F3 CYP4F12	1.53e-06	5	108	3	GO:0052871
GeneOntologyMolecularFunction	leukotriene-B4 20-monooxygenase activity	CYP4F2 CYP4F3 CYP4F12	5.30e-06	7	108	3	GO:0050051
GeneOntologyMolecularFunction	alkane 1-monooxygenase activity	CYP4F2 CYP4F3 CYP4F12	5.30e-06	7	108	3	GO:0018685
GeneOntologyMolecularFunction	arachidonate omega-hydroxylase activity	CYP4F2 CYP4F3 CYP4F12	1.80e-05	10	108	3	GO:0052869
GeneOntologyMolecularFunction	fatty acid omega-hydroxylase activity	CYP4F2 CYP4F3 CYP4F12	1.80e-05	10	108	3	GO:0120250
GeneOntologyMolecularFunction	long-chain fatty acid omega-hydroxylase activity	CYP4F2 CYP4F3 CYP4F12	1.80e-05	10	108	3	GO:0102033
GeneOntologyMolecularFunction	20-hydroxy-leukotriene B4 omega oxidase activity	CYP4F2 CYP4F3	2.90e-05	2	108	2	GO:0097258
GeneOntologyMolecularFunction	20-aldehyde-leukotriene B4 20-monooxygenase activity	CYP4F2 CYP4F3	2.90e-05	2	108	2	GO:0097259
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	CYP4F2 CYP4F3 CYP4F12	4.23e-05	13	108	3	GO:0016713
GeneOntologyMolecularFunction	arachidonate epoxygenase activity	CYP4F2 CYP4F3 CYP4F12	2.87e-04	24	108	3	GO:0008392
GeneOntologyMolecularFunction	arachidonate monooxygenase activity	CYP4F2 CYP4F3 CYP4F12	4.09e-04	27	108	3	GO:0008391
GeneOntologyMolecularFunction	kinase activity	NRBP1 GALK2 CDK12 TAOK2 FAM20C LIMK1 TRIB3 COQ8A ETNK2 MAP3K15 NME6 FAM20A	8.72e-04	764	108	12	GO:0016301
GeneOntologyMolecularFunction	aromatase activity	CYP4F2 CYP4F3 CYP4F12	8.88e-04	35	108	3	GO:0070330
GeneOntologyMolecularFunction	3'-5'-RNA exonuclease activity	DIS3 HELZ2 NOCT	1.05e-03	37	108	3	GO:0000175
GeneOntologyMolecularFunction	RNA exonuclease activity, producing 5'-phosphomonoesters	DIS3 HELZ2 NOCT	1.31e-03	40	108	3	GO:0016896
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP4F2 CYP4F3 CYP4F12	1.31e-03	40	108	3	GO:0016709
GeneOntologyMolecularFunction	structural constituent of postsynaptic density	SHANK1 DLG4	1.54e-03	11	108	2	GO:0098919
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	NRBP1 GALK2 CDK12 TAOK2 FAM20C LIMK1 TRIB3 COQ8A ETNK2 MAP3K15 FAM20A	1.59e-03	709	108	11	GO:0016773
GeneOntologyMolecularFunction	scaffold protein binding	SHANK1 GRID2 GRM2 DLG4	1.63e-03	93	108	4	GO:0097110
GeneOntologyMolecularFunction	RNA exonuclease activity	DIS3 HELZ2 NOCT	1.85e-03	45	108	3	GO:0004532
GeneOntologyMolecularFunction	structural constituent of postsynaptic specialization	SHANK1 DLG4	2.17e-03	13	108	2	GO:0098879
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	CYP4F2 CYP4F3 CYP4F12	2.37e-03	49	108	3	GO:0016712
GeneOntologyMolecularFunction	arachidonate binding	CYP4F2 CYP4F12	2.91e-03	15	108	2	GO:0050544
GeneOntologyMolecularFunction	icosanoid binding	CYP4F2 CYP4F12	3.31e-03	16	108	2	GO:0050542
GeneOntologyMolecularFunction	icosatetraenoic acid binding	CYP4F2 CYP4F12	3.31e-03	16	108	2	GO:0050543
GeneOntologyBiologicalProcess	DNA methylation-dependent constitutive heterochromatin formation	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B MPHOSPH8	1.02e-07	44	107	6	GO:0006346
GeneOntologyBiologicalProcess	facultative heterochromatin formation	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B MPHOSPH8	3.99e-07	55	107	6	GO:0140718
GeneOntologyBiologicalProcess	leukotriene B4 catabolic process	CYP4F2 CYP4F3 CYP4F12	2.68e-06	6	107	3	GO:0036101
GeneOntologyBiologicalProcess	leukotriene B4 metabolic process	CYP4F2 CYP4F3 CYP4F12	4.68e-06	7	107	3	GO:0036102
GeneOntologyBiologicalProcess	leukotriene catabolic process	CYP4F2 CYP4F3 CYP4F12	7.46e-06	8	107	3	GO:0036100
GeneOntologyBiologicalProcess	icosanoid catabolic process	CYP4F2 CYP4F3 CYP4F12	2.17e-05	11	107	3	GO:1901523
GeneOntologyBiologicalProcess	long-chain fatty acid catabolic process	CYP4F2 CYP4F3 CYP4F12	2.89e-05	12	107	3	GO:0042758
GeneOntologyBiologicalProcess	menaquinone catabolic process	CYP4F2 CYP4F12	7.97e-05	3	107	2	GO:0042361
GeneOntologyBiologicalProcess	skeletal muscle fiber development	KLHL40 RYR1 CNTNAP2 PLEC	1.21e-04	49	107	4	GO:0048741
GeneOntologyBiologicalProcess	menaquinone metabolic process	CYP4F2 CYP4F12	1.59e-04	4	107	2	GO:0009233
GeneOntologyBiologicalProcess	phylloquinone metabolic process	CYP4F2 CYP4F12	1.59e-04	4	107	2	GO:0042374
GeneOntologyBiologicalProcess	phylloquinone catabolic process	CYP4F2 CYP4F12	1.59e-04	4	107	2	GO:0042376
GeneOntologyBiologicalProcess	vitamin K catabolic process	CYP4F2 CYP4F12	1.59e-04	4	107	2	GO:0042377
GeneOntologyBiologicalProcess	myotube cell development	KLHL40 RYR1 CNTNAP2 PLEC	1.77e-04	54	107	4	GO:0014904
GeneOntologyBiologicalProcess	fatty acid derivative catabolic process	CYP4F2 CYP4F3 CYP4F12	1.95e-04	22	107	3	GO:1901569
GeneOntologyBiologicalProcess	heterochromatin formation	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B MPHOSPH8	2.08e-04	163	107	6	GO:0031507
GeneOntologyBiologicalProcess	vocalization behavior	SHANK1 CNTNAP2 DLG4	2.54e-04	24	107	3	GO:0071625
GeneOntologyBiologicalProcess	hemidesmosome assembly	LAMA3 PLEC	3.95e-04	6	107	2	GO:0031581
GeneOntologyBiologicalProcess	vitamin E metabolic process	CYP4F2 CYP4F12	3.95e-04	6	107	2	GO:0042360
GeneOntologyBiologicalProcess	prostaglandin catabolic process	CYP4F2 CYP4F12	3.95e-04	6	107	2	GO:1905344
GeneOntologyBiologicalProcess	prostanoid catabolic process	CYP4F2 CYP4F12	3.95e-04	6	107	2	GO:0062232
MousePheno	conical molar	FAM20C FAM20A	3.23e-05	2	80	2	MP:0030500
MousePheno	conical tooth	FAM20C FAM20A	3.23e-05	2	80	2	MP:0030499
Domain	MeCpG-bd_2/3_C_dom	MBD3L5 MBD3L2 MBD3L3 MBD3L4	3.26e-08	7	105	4	IPR025884
Domain	MBD2/MBD3_p55-bd	MBD3L5 MBD3L2 MBD3L3 MBD3L4	3.26e-08	7	105	4	IPR032343
Domain	MBD_C	MBD3L5 MBD3L2 MBD3L3 MBD3L4	3.26e-08	7	105	4	PF14048
Domain	MBDa	MBD3L5 MBD3L2 MBD3L3 MBD3L4	3.26e-08	7	105	4	PF16564
Domain	FAM20	FAM20C FAM20A	9.36e-05	3	105	2	IPR024869
Domain	FAM20_C	FAM20C FAM20A	9.36e-05	3	105	2	IPR009581
Domain	LISCH7	ILDR2 ILDR1	9.36e-05	3	105	2	IPR008664
Domain	LSR	ILDR2 ILDR1	9.36e-05	3	105	2	PF05624
Domain	Fam20C	FAM20C FAM20A	9.36e-05	3	105	2	PF06702
Domain	RNase_II/R_CS	DIS3 HELZ2	1.86e-04	4	105	2	IPR022966
Domain	PDZ	SHANK1 ARHGEF12 PARD6G LIMK1 DLG4	1.20e-03	141	105	5	PF00595
Domain	PDZ	SHANK1 ARHGEF12 PARD6G LIMK1 DLG4	1.49e-03	148	105	5	SM00228
Domain	-	SHANK1 ARHGEF12 PARD6G LIMK1 DLG4	1.58e-03	150	105	5	2.30.42.10
Domain	PDZ	SHANK1 ARHGEF12 PARD6G LIMK1 DLG4	1.63e-03	151	105	5	PS50106
Domain	PDZ	SHANK1 ARHGEF12 PARD6G LIMK1 DLG4	1.68e-03	152	105	5	IPR001478
Domain	Cyt_P450_E_grp-I	CYP4F2 CYP4F3 CYP4F12	2.06e-03	45	105	3	IPR002401
Domain	START	STARD13 STARD8	2.35e-03	13	105	2	SM00234
Domain	uDENN	DENND1A SBF2	2.73e-03	14	105	2	SM00800
Domain	START	STARD13 STARD8	3.13e-03	15	105	2	PF01852
Domain	START_lipid-bd_dom	STARD13 STARD8	3.13e-03	15	105	2	IPR002913
Domain	uDENN	DENND1A SBF2	3.13e-03	15	105	2	PF03456
Domain	START	STARD13 STARD8	3.13e-03	15	105	2	PS50848
Domain	Cyt_P450_CS	CYP4F2 CYP4F3 CYP4F12	3.30e-03	53	105	3	IPR017972
Domain	UDENN	DENND1A SBF2	3.57e-03	16	105	2	PS50946
Domain	DDENN	DENND1A SBF2	3.57e-03	16	105	2	PS50947
Domain	DENN	DENND1A SBF2	3.57e-03	16	105	2	SM00799
Domain	dDENN	DENND1A SBF2	3.57e-03	16	105	2	SM00801
Domain	DENN	DENND1A SBF2	3.57e-03	16	105	2	PF02141
Domain	dDENN_dom	DENND1A SBF2	3.57e-03	16	105	2	IPR005112
Domain	uDENN_dom	DENND1A SBF2	3.57e-03	16	105	2	IPR005113
Domain	dDENN	DENND1A SBF2	3.57e-03	16	105	2	PF03455
Domain	DENN	DENND1A SBF2	3.57e-03	16	105	2	PS50211
Domain	DENN_dom	DENND1A SBF2	3.57e-03	16	105	2	IPR001194
Domain	CYTOCHROME_P450	CYP4F2 CYP4F3 CYP4F12	4.05e-03	57	105	3	PS00086
Domain	-	CYP4F2 CYP4F3 CYP4F12	4.26e-03	58	105	3	1.10.630.10
Domain	p450	CYP4F2 CYP4F3 CYP4F12	4.26e-03	58	105	3	PF00067
Domain	Cyt_P450	CYP4F2 CYP4F3 CYP4F12	4.68e-03	60	105	3	IPR001128
Pathway	REACTOME_EICOSANOIDS	CYP4F2 CYP4F3 CYP4F12	3.59e-05	12	79	3	M27129
Pathway	REACTOME_EICOSANOIDS	CYP4F2 CYP4F3 CYP4F12	3.59e-05	12	79	3	MM14845
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES	CYP4F2 CYP4F3 CYP4F12	5.90e-05	14	79	3	MM15842
Pathway	REACTOME_FATTY_ACIDS	CYP4F2 CYP4F3 CYP4F12	7.34e-05	15	79	3	M27126
Pathway	REACTOME_MISCELLANEOUS_SUBSTRATES	CYP4F2 CYP4F3 CYP4F12	1.30e-04	18	79	3	MM14843
Pathway	REACTOME_FATTY_ACIDS	CYP4F2 CYP4F3 CYP4F12	1.30e-04	18	79	3	MM14841
Pathway	REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX	CYP4F2 CYP4F3 CYP4F12	3.56e-04	25	79	3	MM14858
Pubmed	MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	1.57e-12	6	108	5	12504854
Pubmed	Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	1.57e-12	6	108	5	18942147
Pubmed	MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	7.70e-10	15	108	5	15701600
Pubmed	Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.	CYP4F2 CYP4F3 CYP4F12	1.16e-07	4	108	3	18065749
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CDK12 CUL9 DENND1A ADCY7 RYR1 TAOK2 FAM20C TRIB3 ZNF408 SBF2 NCAPD2 HELZ2 ZFYVE26 LRRC14 PLEC CABIN1	3.18e-07	1105	108	16	35748872
Pubmed	The cytochrome P450 4 (CYP4) family.	CYP4F2 CYP4F3 CYP4F12	5.78e-07	6	108	3	9068972
Pubmed	Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.	SHANK1 GRID2 DLG4	1.01e-06	7	108	3	15207857
Pubmed	Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.	CYP4F2 CYP4F12	9.55e-06	2	108	2	18662666
Pubmed	Expression and physiological function of CYP4F subfamily in human eosinophils.	CYP4F3 CYP4F12	9.55e-06	2	108	2	17980168
Pubmed	Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.	CYP4F2 CYP4F3	9.55e-06	2	108	2	8026587
Pubmed	A new calcineurin inhibition domain in Cabin1.	PPP3R2 CABIN1	9.55e-06	2	108	2	17531200
Pubmed	Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.	SHANK1 DLG4	9.55e-06	2	108	2	18272690
Pubmed	Novel autosomal recessive LAMA3 and PLEC variants underlie junctional epidermolysis bullosa generalized intermediate and epidermolysis bullosa simplex with muscular dystrophy in two consanguineous families.	LAMA3 PLEC	9.55e-06	2	108	2	29797489
Pubmed	Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome.	FAM20C FAM20A	2.86e-05	3	108	2	21549343
Pubmed	Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.	CYP4F2 CYP4F3	2.86e-05	3	108	2	15145985
Pubmed	Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin.	SHANK1 DLG4	2.86e-05	3	108	2	10433268
Pubmed	Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice.	FAM20C FAM20A	2.86e-05	3	108	2	22732358
Pubmed	Clustering of neuronal potassium channels is independent of their interaction with PSD-95.	CNTNAP2 DLG4	2.86e-05	3	108	2	12438413
Pubmed	The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins.	FAM20C FAM20A	2.86e-05	3	108	2	22900076
Pubmed	FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells.	FAM20C FAM20A	2.86e-05	3	108	2	15676076
Pubmed	The DNA sequence and biology of human chromosome 19.	MBD3L5 MBD3L3 CYP4F2 MBD3L4 YJEFN3 RYR1 ZNF749	3.10e-05	284	108	7	15057824
Pubmed	Association study of IL-17RC, CHL1, DSCAM and CNTNAP2 genes polymorphisms with adolescent idiopathic scoliosis susceptibility in a Chinese Han population.	IL17RC CNTNAP2	5.71e-05	4	108	2	22744455
Pubmed	IQ-ArfGEF/BRAG1 is a guanine nucleotide exchange factor for Arf6 that interacts with PSD-95 at postsynaptic density of excitatory synapses.	ARHGEF12 DLG4	5.71e-05	4	108	2	18164504
Pubmed	Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons.	CNTNAP2 DLG4	5.71e-05	4	108	2	19109503
Pubmed	Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.	CYP4F2 CYP4F12	5.71e-05	4	108	2	22665481
Pubmed	Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.	CYP4F2 CYP4F12	5.71e-05	4	108	2	11185557
Pubmed	Biochemical and morphological characterization of SEPT1 in mouse brain.	SEPTIN1 DLG4	5.71e-05	4	108	2	32146512
Pubmed	An approximately 1.2-Mb bacterial artificial chromosome contig refines the genetic and physical maps of the lurcher locus on mouse chromosome 6.	GRID2 DNAH11	5.71e-05	4	108	2	9253602
Pubmed	Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.	LIMK1 DLG4	9.50e-05	5	108	2	36301793
Pubmed	Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.	CYP4F2 CYP4F12	9.50e-05	5	108	2	22969154
Pubmed	ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons.	CNTNAP2 DLG4	9.50e-05	5	108	2	20089912
Pubmed	Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.	SHANK1 DLG4	9.50e-05	5	108	2	16606358
Pubmed	Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.	CYP4F2 CYP4F12	9.50e-05	5	108	2	21466787
Pubmed	Angulin proteins ILDR1 and ILDR2 regulate alternative pre-mRNA splicing through binding to splicing factors TRA2A, TRA2B, or SRSF1.	ILDR2 ILDR1	9.50e-05	5	108	2	28785060
Pubmed	Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.	ILDR2 ILDR1	9.50e-05	5	108	2	23239027
Pubmed	Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.	CYP4F2 CYP4F3	9.50e-05	5	108	2	18577768
Pubmed	Insulin receptor substrate of 53 kDa links postsynaptic shank to PSD-95.	SHANK1 DLG4	9.50e-05	5	108	2	15255944
Pubmed	A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.	ARHGEF12 CUL9 XPC NFE2L2	1.40e-04	84	108	4	34591642
Pubmed	ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4.	RBL2 XPC	1.42e-04	6	108	2	19644500
Pubmed	Junctional Epidermolysis Bullosa	LAMA3 PLEC	1.42e-04	6	108	2	20301304
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TCAF2 NACC1 NOL6 PARD6G XPC DCAF12L2 RYR1 COQ8A DNAH11	1.74e-04	638	108	9	31182584
Pubmed	The DNA sequence and analysis of human chromosome 13.	STARD13 DIS3 FREM2 INTS6 MPHOSPH8	1.95e-04	170	108	5	15057823
Pubmed	Nicotine regulates multiple synaptic proteins by inhibiting proteasomal activity.	SHANK1 DLG4	1.99e-04	7	108	2	17898222
Pubmed	Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.	CYP4F2 CYP4F12	1.99e-04	7	108	2	22160543
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 NACC1 ARHGEF12 GRM2 TAOK2 TJAP1 DLG4 CABIN1 TP53BP2 TMEM240 FERMT3	2.08e-04	963	108	11	28671696
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CDK12 NOL6 RBM42 ARHGEF12 XPC DENND1A TAOK2 ESYT2 INTS6 NCAPD2 HELZ2 MPHOSPH8 ATP5F1B KIF22	2.24e-04	1497	108	14	31527615
Pubmed	A secretory kinase complex regulates extracellular protein phosphorylation.	FAM20C FAM20A	2.64e-04	8	108	2	25789606
Pubmed	The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.	SHANK1 DLG4	2.64e-04	8	108	2	10958799
Pubmed	Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.	SHANK1 DLG4	2.64e-04	8	108	2	19640847
Pubmed	Secreted kinase phosphorylates extracellular proteins that regulate biomineralization.	FAM20C FAM20A	2.64e-04	8	108	2	22582013
Pubmed	Sex Hormones Regulate SHANK Expression.	SHANK1 DLG4	2.64e-04	8	108	2	30319350
Pubmed	Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.	LAMA3 NCAPD2 ATP5F1B	2.85e-04	41	108	3	19343720
Pubmed	Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4.	FBLN1 PLEC ATP5F1B	3.28e-04	43	108	3	30026490
Pubmed	Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.	LAMA3 PLEC	3.39e-04	9	108	2	12482924
Pubmed	Superresolution imaging of chemical synapses in the brain.	SHANK1 DLG4	3.39e-04	9	108	2	21144999
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	CBFA2T3 KCTD17 FREM2 NCAPD2 SEPTIN1 MAP3K15 ATP5F1B	4.07e-04	431	108	7	33660365
Pubmed	Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity.	CNTNAP2 PLEC	4.23e-04	10	108	2	19625254
Pubmed	Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.	DLG4 TAC1	4.23e-04	10	108	2	22427743
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	NOL6 TRAFD1 NCAPD2 PLEC KIF22	5.15e-04	210	108	5	16565220
Pubmed	Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.	PKD1L1 DNAH11	5.16e-04	11	108	2	27272319
Pubmed	The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.	LAMA3 PLEC	5.16e-04	11	108	2	10811835
Pubmed	Behavioral phenotypes of genetic mouse models of autism.	SHANK1 CNTNAP2	5.16e-04	11	108	2	26403076
Pubmed	Current insights into the formation and breakdown of hemidesmosomes.	LAMA3 PLEC	5.16e-04	11	108	2	16757171
Pubmed	Genome-wide association study of body mass index in 23 000 individuals with and without asthma.	STARD13 DENND1A	5.16e-04	11	108	2	23517042
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SPTLC2 NOL6 RANBP6 PGAP4 DENND1A DIS3 ESYT2 TRAFD1 RFLNB COQ8A NCAPD2 CABIN1 ATP5F1B	5.32e-04	1440	108	13	30833792
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	CUL9 CYP4F2 RYR1 DLG4 TP53BP2 KIF22	5.83e-04	329	108	6	17474147
Pubmed	A role for Saccharomyces cerevisiae Centrin (Cdc31) in mitochondrial function and biogenesis.	XPC ATP5F1B	6.18e-04	12	108	2	30251372
Pubmed	Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.	LIMK1 DLG4	6.18e-04	12	108	2	26969129
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 NRBP1 RBL2 CUL9 XPC LIMK1 NFE2L2 DLG4 PLEC CABIN1 ATP5F1B B4GALT3	6.55e-04	1285	108	12	35914814
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NACC1 CDK12 XPC ESYT2 TRAFD1 SHCBP1 HELZ2 TJAP1 PLEC	7.05e-04	774	108	9	15302935
Pubmed	A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.	SHANK1 DLG4	7.29e-04	13	108	2	15673434
Pubmed	Genomic analysis of synaptotagmin genes.	SYT9 ESYT2	7.29e-04	13	108	2	11543631
Pubmed	AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication.	GRID2 DLG4	8.48e-04	14	108	2	33305180
Pubmed	Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.	SHANK1 DLG4	8.48e-04	14	108	2	21795692
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	NRBP1 SBF2 SHCBP1 ILDR1 LRRC14 ATP5F1B	9.44e-04	361	108	6	18976975
Pubmed	Analysis of BCL6-interacting proteins by tandem mass spectrometry.	SPTLC2 TRIB3 HELZ2	9.64e-04	62	108	3	16147992
Pubmed	The endoplasmic reticulum stress response in aging and age-related diseases.	TRIB3 NFE2L2	9.77e-04	15	108	2	22934019
Pubmed	Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.	TJAP1 DLG4	1.11e-03	16	108	2	21920314
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	LAMA3 DLG4	1.11e-03	16	108	2	30579834
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	LAMA3 FREM2	1.11e-03	16	108	2	16880404
Pubmed	Genomic analysis of mouse retinal development.	WNT6 CUL9 CENPK TAOK2 TRAFD1 NCAPD2 DLG4 ZFYVE26 TAC1 PLEC	1.18e-03	1006	108	10	15226823
Pubmed	Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse.	FBLN1 DLG4 TAC1	1.21e-03	67	108	3	16987237
Pubmed	Identification of the human testis protein phosphatase 1 interactome.	NRBP1 TP53BP2 ATP5F1B	1.26e-03	68	108	3	21382349
Pubmed	Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.	CNTNAP2 TAC1	1.26e-03	17	108	2	26389685
Pubmed	Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.	CYP4F2 CYP4F3 CYP4F12	1.37e-03	70	108	3	15128046
Pubmed	Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function.	LIMK1 DLG4	1.42e-03	18	108	2	30833597
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	CDK12 DIS3 HELZ2 SEPTIN1 MPHOSPH8 PLEC ATP5F1B FERMT3	1.57e-03	701	108	8	30196744
Pubmed	Compensation by tumor suppressor genes during retinal development in mice and humans.	RBL2 DLG4	1.58e-03	19	108	2	16672052
Pubmed	Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.	DCAF12L1 NFE2L2	1.58e-03	19	108	2	17660561
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	CDK12 SPTLC2 RYR1 FREM2 INTS6 HELZ2 DNAH11	1.71e-03	552	108	7	10737800
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	CDK12 GRM2 TAOK2 CYP4F12 B4GALT3	1.74e-03	276	108	5	28319085
Pubmed	The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling.	LIMK1 DLG4	1.93e-03	21	108	2	31577955
Pubmed	Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.	CNTNAP2 DLG4	1.93e-03	21	108	2	25707359
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	LAMA3 FREM2	1.93e-03	21	108	2	27856617
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	NXPE4 FAM20C PLEC FAM20A ATP5F1B B4GALT3	1.96e-03	417	108	6	19199708
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	DIS3 KCTD17 TRAFD1 COQ8A NFE2L2 NCAPD2 ATP5F1B	2.07e-03	571	108	7	37167062
Pubmed	Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.	PLEC TP53BP2	2.32e-03	23	108	2	26933062
Pubmed	Functional proteomics mapping of a human signaling pathway.	STARD13 CDK12 RANBP6 XPC FBLN1 PLEC TP53BP2	2.51e-03	591	108	7	15231748
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	NOL6 FREM2 FAM20C PLEC ATP5F1B	2.57e-03	302	108	5	30561431
Pubmed	Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis.	LAMA3 FAM20C	2.74e-03	25	108	2	25085501
Cytoband	19p13.2	MBD3L5 NACC1 MBD3L2 MBD3L3 MBD3L4 MBD3L2B CYP4F3	1.27e-06	229	108	7	19p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	MBD3L5 NACC1 MBD3L2 MBD3L3 CYP4F2 MBD3L4 YJEFN3 MBD3L2B CYP4F3 CYP4F12	1.97e-05	797	108	10	chr19p13
GeneFamily	PDZ domain containing	SHANK1 ARHGEF12 PARD6G LIMK1 DLG4	2.01e-04	152	64	5	1220
GeneFamily	Cytochrome P450 family 4	CYP4F2 CYP4F3 CYP4F12	2.78e-04	36	64	3	1003
GeneFamily	StAR related lipid transfer domain containing	STARD13 STARD8	1.26e-03	15	64	2	759
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	TAOK2 MAP3K15	3.24e-03	24	64	2	654
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND1A SBF2	3.51e-03	25	64	2	504
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYT9 FAM20C ESYT2 SLC9A4 SHCBP1 FAM20A	6.81e-06	189	108	6	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYT9 FAM20C ESYT2 SLC9A4 SHCBP1 FAM20A	6.81e-06	189	108	6	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	STARD13 STARD8 SPTLC2 DENND1A PRSS36 RYR1	7.01e-06	190	108	6	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SYT9 CHST6 GRID2 PPP3R2 CNTNAP2 FAM20A	9.40e-06	200	108	6	6a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SYT9 CHST6 GRID2 PPP3R2 CNTNAP2 FAM20A	9.40e-06	200	108	6	8d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SYT9 CHST6 GRID2 PPP3R2 CNTNAP2 FAM20A	9.40e-06	200	108	6	cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NXPE4 RYR1 RFLNB MAP3K15 OSGIN2	4.57e-05	161	108	5	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	6.25e-05	172	108	5	35c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT9 CENPK SHCBP1 NCAPD2 KIF22	7.15e-05	177	108	5	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT9 CENPK SHCBP1 NCAPD2 KIF22	7.15e-05	177	108	5	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CBFA2T3 PPM1J INTS6 NCAPD2 NOCT	7.15e-05	177	108	5	68f1139fc378f351e3b9e9f392aacb150025bf03
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|343B / Donor, Lineage, Cell class and subclass (all cells)	TCAF2 CUL9 ADCY7 RYR1 ZNF408	7.54e-05	179	108	5	c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PARD6G CENPK KCTD17 SHCBP1 KIF22	7.54e-05	179	108	5	df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCell	Basal\|World / shred by cell class for mouse tongue	LAMA3 FREM2 COQ8A TJAP1 PLEC	8.37e-05	183	108	5	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 C12orf56 ILDR1 ATP5F1B DNAH11	8.37e-05	183	108	5	6b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SYT9 SLC9A4 SHCBP1 FAM20A	8.37e-05	183	108	5	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM20C ESYT2 SLC9A4 MAP3K15 FAM20A	8.81e-05	185	108	5	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SYT9 SLC9A4 SHCBP1 FAM20A	8.81e-05	185	108	5	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	8.81e-05	185	108	5	736bf89a7a1a840ab6920060f2d98598332065a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SYT9 SLC9A4 SHCBP1 FAM20A	9.27e-05	187	108	5	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	9.50e-05	188	108	5	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SLC9A4 SHCBP1 MAP3K15 FAM20A	9.50e-05	188	108	5	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SYT9 SLC9A4 SHCBP1 FAM20A	9.74e-05	189	108	5	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SLC9A4 SHCBP1 MAP3K15 FAM20A	9.99e-05	190	108	5	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SLC9A4 SHCBP1 MAP3K15 FAM20A	9.99e-05	190	108	5	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	9.99e-05	190	108	5	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.02e-04	191	108	5	b978afe76754cc56e1672abca27be289bb56375b
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.02e-04	191	108	5	f764cc21fef87ebad765011098f647ae1bdf6158
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYT9 FAM20C SLC9A4 SHCBP1 FAM20A	1.05e-04	192	108	5	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.05e-04	192	108	5	5ef79faddb433c09ff36660d8bf7a3af5a67bf1d
ToppCell	Proliferating\|World / shred by cell class for mouse tongue	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.05e-04	192	108	5	f081f3f957cc782294e118fcc1055f6a4264ee98
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.07e-04	193	108	5	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	droplet-Tongue-nan-3m-Epithelial-proliferating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.10e-04	194	108	5	2cac1b9c4da01faaec9a67ec06f47a7060760225
ToppCell	droplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD6G RFLNB COQ8A NFE2L2 NOCT	1.10e-04	194	108	5	37803f4abf1aa1ad771c9cd293933003d7101e70
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 PRSS36 RYR1 FAM20A FERMT3	1.10e-04	194	108	5	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-proliferating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.13e-04	195	108	5	b57132802cb977551e214880984f3edcd375474f
ToppCell	COVID-19-Lymphoid-Proliferating_CD4_T_cells\|COVID-19 / Condition, Lineage and Cell class	CENPK SHCBP1 NCAPD2 SEPTIN1 KIF22	1.24e-04	199	108	5	e1dfc856a85a91e8f7ab8d600a8a891d16b2aefb
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_ventral_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.24e-04	199	108	5	446cd7d960812519fe2b8e434578ef0b668c75ce
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.24e-04	199	108	5	d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CENPK SHCBP1 ETNK2 NCAPD2 KIF22	1.24e-04	199	108	5	c7c501ad144ac5488d0b0496554d46616f2e01a6
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	STARD8 PRSS36 NME6 PLEC FERMT3	1.27e-04	200	108	5	88d713dfc792e7609bf7ecfb28f87cb748088570
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.27e-04	200	108	5	14c9ced92763858f3d35186cd3908bd0f4cfd872
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CENPK SHCBP1 NCAPD2 SEPTIN1 KIF22	1.27e-04	200	108	5	535f6fba8d03873ba35c9949579161dc41cd7a60
ToppCell	Severe_COVID-19-T/NK-proliferating_T/NK\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CENPK SHCBP1 NCAPD2 SEPTIN1 KIF22	1.27e-04	200	108	5	52265e761a961f3724b388285e0919bd58847138
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.27e-04	200	108	5	dd5b753bb1333fa502b9d3a6d65a53a9882b2451
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CENPK SHCBP1 NCAPD2 SEPTIN1 KIF22	1.27e-04	200	108	5	3c3ac587ad98e3f6be809eac18c7742a23140de1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_ventral_progenitors\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CENPK FBLN1 SHCBP1 NCAPD2 KIF22	1.27e-04	200	108	5	9359faa749f41aaef70b4874f20b4eed2dc12cc2
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CENPK SHCBP1 NCAPD2 SEPTIN1 KIF22	1.27e-04	200	108	5	5c84aaedac9f27da0da0493dab7c8f7a4d66888c
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CENPK SHCBP1 NCAPD2 SEPTIN1 KIF22	1.27e-04	200	108	5	60d11275f06490f86f400a2802492f9c1b570400
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CENPK SHCBP1 NCAPD2 SEPTIN1 KIF22	1.27e-04	200	108	5	dd7ad295ab3ba4c19babffb1625900db414bb5a9
ToppCell	BAL-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CENPK SHCBP1 NCAPD2 SEPTIN1 KIF22	1.27e-04	200	108	5	0e44a55d65b72eb40543d3bde301f8598ac251c3
Disease	Acidosis	SLC9A4 NFE2L2	1.03e-05	2	95	2	C0001122
Disease	Metabolic acidosis	SLC9A4 NFE2L2	1.03e-05	2	95	2	C0220981
Disease	gonadal dysgenesis (implicated_via_orthology)	STARD13 STARD8	6.13e-05	4	95	2	DOID:14447 (implicated_via_orthology)
Disease	Williams Syndrome	LIMK1 DLG4	2.84e-04	8	95	2	C0175702
Disease	Williams-Beuren syndrome (implicated_via_orthology)	LIMK1 DLG4	1.05e-03	15	95	2	DOID:1928 (implicated_via_orthology)
Disease	creatinine measurement	NRBP1 CDK12 PPM1J RYR1 SLC9A4 DCAF12L1 NFE2L2 ILDR1 PLEC NOCT	1.38e-03	995	95	10	EFO_0004518
Disease	susceptibility to chronic sinus infection measurement	RANBP6 CNTNAP2 MAP3K15	1.39e-03	68	95	3	EFO_0008419
Disease	autism spectrum disorder (implicated_via_orthology)	SHANK1 TAOK2 CNTNAP2 DLG4	1.50e-03	152	95	4	DOID:0060041 (implicated_via_orthology)
Disease	parahippocampal gyrus volume measurement	FREM2 NOCT	1.52e-03	18	95	2	EFO_0010318
Disease	diet measurement, body mass index	GRID2 CNTNAP2	1.88e-03	20	95	2	EFO_0004340, EFO_0008111
Disease	glioma	FAM20C CYP4F12	2.27e-03	22	95	2	EFO_0005543
Disease	traumatic brain injury (biomarker_via_orthology)	PPP3R2 NFE2L2	2.70e-03	24	95	2	DOID:0081292 (biomarker_via_orthology)
Disease	Micronuclei, Chromosome-Defective	XPC NFE2L2	3.17e-03	26	95	2	C1449861
Disease	Micronuclei, Genotoxicant-Induced	XPC NFE2L2	3.17e-03	26	95	2	C1449862

Protein segments in the cluster

Peptide	Gene	Start	Entry
ALRVLHLEKRERPPD	ESYT2	651	A0FGR8
PRSRTAIIVPHRARE	B4GALT3	121	O60512
EAAIREHRRTLTPVP	ARSH	511	Q5FYA8
QDLRFARVPLALHPV	CDK12	1401	Q9NYV4
LFALDRINRDPHLLP	GRM2	66	Q14416
FPALDVPRRRKLHFE	DNAH11	2121	Q96DT5
LPELRHNPLVRRVID	PPP3R2	46	Q96LZ3
FEREYRLAPIPRARH	ADCY7	581	P51828
ARRVHFALLPERYEP	C1orf115	66	Q9H7X2
VRFFLRHERPPGRDI	TP53BP2	76	Q13625
LLLRAAPTAVHPVRD	ATP5F1B	31	P06576
RRPELIPEDLHRHYI	ARHGEF12	451	Q9NZN5
ILRPAFVPHVLQRAD	RBM42	156	Q9BTD8
PHIFSRRERCRPIDL	IQCM	111	A0A1B0GVH7
LRELDPDQPRRLHTF	INTS6	601	Q9UL03
HLRVRPADLPVAERA	KCTD19	111	Q17RG1
LPPHFRERTERLERN	RBL2	141	Q08999
RHFLLDGEPRPVAVR	LAMA3	911	Q16787
LRVHILPFPEINEAR	SBF2	486	Q86WG5
TLARALHELRRFLPP	MESP2	96	Q0VG99
LQRFVIRIHPVDRLP	FREM2	686	Q5SZK8
VYAHIRPRDVEAIPR	DCAF12L2	241	Q5VW00
IFRRPVTRIRSHPDN	MBD3L5	56	A6NJ08
LEPEHIREPRLFRLI	ETNK2	161	Q9NVF9
VRPPVYLHDVILRVV	GRID2	146	O43424
PARVRVAVRLRPFVD	KIF22	41	Q14807
RDELRAKALHIPFPV	NFE2L2	456	Q16236
PATRRVQVAEHPRLL	GALK2	6	Q01415
ERRIIHLPPLIRDLS	ILDR1	326	Q86SU0
IFRRPVTRIRSHPDN	MBD3L2B	56	A0A1B0GVZ6
DIYDVLIRLSPRHIP	NOL6	1006	Q9H6R4
RRPAFPVIHLEDITL	DEFB125	66	Q8N687
SRVERHPLVRAQPEL	KLHL40	236	Q2TBA0
FPVLEHLLRARFSEP	PGAP4	221	Q9BRR3
DPRELRERHRPLVVP	CBFA2T3	361	O75081
RERHRPLVVPGSRQE	CBFA2T3	366	O75081
LHLRIFDPSPEDIAR	GTPBP8	66	Q8N3Z3
RPHPLRPEAELAVRA	KCTD17	271	Q8N5Z5
IFRRPVTRIRSHPDN	MBD3L3	56	A6NE82
LDVRSPRAPVQVIHR	PAAF1	306	Q9BRP4
PRRRAHLDIGLPRDF	PARD6G	126	Q9BYG4
EPARRPTARELLFHP	NRBP1	311	Q9UHY1
PSRPRAERVARLVQH	PRSS36	386	Q5K4E3
RPEEIIFLRAITPPH	FBLN1	611	P23142
PVIHVFRRRVTDPSL	OSGIN2	326	Q9Y236
RLIRIPLARHAFEEG	CABIN1	136	Q9Y6J0
RRRHPGLAVELELEP	FBXL8	246	Q96CD0
HLDRILDFRRVPPVA	FAM20C	316	Q8IXL6
RARLPPEERQRIFLT	CPHXL2	76	A0A1W2PPK0
IALRHPEDPTRIRLE	CENPK	251	Q9BS16
FLPDHTEPRRKLELI	CYP4F12	491	Q9HCS2
PEGLFPEHLIDVLRR	COQ8A	386	Q8NI60
LLRFRVLPDHTEPRR	CYP4F2	486	P78329
DIPREPRRIVIHRGS	DLG4	306	P78352
RSVVHDLPVRVLPRR	HUS1B	126	Q8NHY5
PKLREDRRPITVHFG	DENND1A	481	Q8TEH3
RVRRLCHLLVHVEPP	CUL9	1421	Q8IWT3
VYAHIRPRDVEAIPR	DCAF12L1	241	Q5VU92
QHPIIARYVRIVPLD	CNTNAP2	151	Q9UHC6
LLRFRVLPDHTEPRR	CYP4F3	486	Q08477
RPPTRAELARHRVVV	HELZ2	631	Q9BYK8
EPPFHLDREIRLQRL	SCNN1D	346	P51172
PRERLHLEPIKEYRR	RYR1	816	P21817
ADRIPHKPFIIIARA	PKD1L1	131	Q8TDX9
LEECRAVLHTRPPRF	NOCT	111	Q9UK39
DRLLHPDAVPALFRT	IL17RC	706	Q8NAC3
IFRRPVTRIRSHPDN	MBD3L4	56	A6NDZ8
RLALLEPVFPIACHR	MPHOSPH8	741	Q99549
IFRRPVTRIRSHPDN	MBD3L2	56	Q8NHZ7
IIGILRDFIRSPEHR	MAP3K15	1051	Q6ZN16
HLRDRARPRLRDPDI	SYT9	36	Q86SS6
APPSVVLNRVLRERH	STARD13	961	Q9Y3M8
EEIRYTHILNRVLPP	PUS3	156	Q9BZE2
LPRRPLRAFESDVFH	TRAFD1	181	O14545
ALSPPERERRIKAHL	TCAF2	801	A6NFQ2
PFPIDVFIRRALNVH	NXPE4	441	Q6UWF7
EVRFEPRHRPTRFLS	RFLNB	151	Q8N5W9
AFHLDRILDFRRVPP	FAM20A	266	Q96MK3
FTHLEFPRRVLPKEL	PPM1J	321	Q5JR12
RRVALRPKPLFHAVD	SLC9A4	741	Q6AI14
LKHRFVLRERPPTVI	TAOK2	276	Q9UL54
PRLRLHYDILEDRVP	SHCBP1	226	Q8NEM2
SVLLFLQDPHPRVRA	RANBP6	411	O60518
HLFTPADKRIPRIRI	DIS3	371	Q9Y2L1
APPAVVLHRVLRERA	STARD8	871	Q92502
APEEPERLPLHVRFL	SHANK1	1481	Q9Y566
PALNLRIVHLVRDPR	CHST6	191	Q9GZX3
PFRLPQEHRLFERLR	NCAPD2	836	Q15021
RLDVFLRRHLPPEVY	C12orf56	16	Q8IXR9
LRRHLPPEVYDAVRA	C12orf56	21	Q8IXR9
RGLRPLDVAFLRAVH	SEPTIN1	151	Q8WYJ6
YRKAPPEHRELRLEI	TJAP1	11	Q5JTD0
SLRELGRRPHRPFEE	TMEM240	136	Q5SV17
SDLIQHKRIDLRPRP	ZNF749	541	O43361
RHRLVPLLDRPFDET	SPTLC2	541	O15270
RRRPAEDAHLPRLVS	ILDR2	501	Q71H61
RHRIPEPEAAVLFRQ	TRIB3	151	Q96RU7
DAFPQLPELRRHLIS	ZNF408	531	Q9H9D4
RHFLRALELQPPLAD	YJEFN3	16	A6XGL0
PPFREVGARLLERFH	WNT6	241	Q9Y6F9
PTRVFRARHVAPDSI	NME6	101	O75414
ELKDHLRIFRIPRRP	FERMT3	351	Q86UX7
VHRLRLPLDKEPARE	PLEC	1141	Q15149
RRLHVPELLVAPLQR	PLEKHG7	426	Q6ZR37
IIPARFTRVLPRDVD	XPC	236	Q01831
EPFEHLLQRIARRPK	TAC1	46	P20366
VSHLLFERQVPPERL	ZFYVE26	1196	Q68DK2
LLPEDLRFLARSPHA	LRRC14	321	Q15048
VVCRPHRIFRPSDLI	LIMK1	326	P53667
DPRRKPLDSRVLHAV	NACC1	426	Q96RE7