Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessneuron development

BOC CACNA1A PLXNA3 NRG1 DCDC2 NR2E3 FMR1 ANK3 MYOC FSTL4 DAB2 CDH23 ATP8B1 INPP5F DCC PCDH12 PIP5K1C TH MFSD2A CPNE6 PTPRZ1 RP1L1 NECTIN1 NGF COBL HERC1 CX3CL1 CNTN2 OTOG

5.49e-06146316629GO:0048666
GeneOntologyCellularComponentcell-cell contact zone

XIRP1 ANK2 ANK3 PKP4 NECTIN1 PCDH9

1.16e-04941696GO:0044291
GeneOntologyCellularComponentmatrilin complex

MATN3 MATN4

3.86e-0441692GO:0120216
GeneOntologyCellularComponentnode of Ranvier

ANK3 MYOC CNTN2

5.35e-04201693GO:0033268
GeneOntologyCellularComponentcostamere

ANK2 ANK3 AHNAK2

7.14e-04221693GO:0043034
GeneOntologyCellularComponentpostsynaptic specialization

NRG1 IQSEC3 FMR1 ANK2 ANK3 PCLO PKP4 DLGAP4 DCC PIP5K1C PTPRZ1 TANC1

8.29e-0450316912GO:0099572
GeneOntologyCellularComponentgrowth cone

BOC FMR1 PCLO DCC PTPRZ1 NECTIN1 COBL PCDH9

8.78e-042451698GO:0030426
GeneOntologyCellularComponentaxon

BOC NRG1 FMR1 ANK3 MYOC PCLO INPP5F DCC TH CPNE6 PTPRZ1 NECTIN1 NGF COBL TANC1 PCDH9 CNTN2

9.19e-0489116917GO:0030424
GeneOntologyCellularComponentsite of polarized growth

BOC FMR1 PCLO DCC PTPRZ1 NECTIN1 COBL PCDH9

1.08e-032531698GO:0030427
GeneOntologyCellularComponentpostsynaptic density

NRG1 IQSEC3 FMR1 ANK2 ANK3 PCLO PKP4 DCC PIP5K1C PTPRZ1 TANC1

1.14e-0345116911GO:0014069
GeneOntologyCellularComponentneuron to neuron synapse

NRG1 IQSEC3 FMR1 ANK2 ANK3 PCLO PKP4 DCC PIP5K1C PTPRZ1 NECTIN1 TANC1

1.16e-0352316912GO:0098984
DomainDC

DCDC2 DCDC1 RP1L1

3.54e-0581633PS50309
DomainDoublecortin_dom

DCDC2 DCDC1 RP1L1

3.54e-0581633IPR003533
DomainIGc2

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 MCAM DCC NECTIN1 IL1RL1 CNTN2

4.22e-0523516310SM00408
DomainIg_sub2

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 MCAM DCC NECTIN1 IL1RL1 CNTN2

4.22e-0523516310IPR003598
Domainig

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 MCAM TIE1 NECTIN1 CNTN2

4.49e-051901639PF00047
DomainImmunoglobulin

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 MCAM TIE1 NECTIN1 CNTN2

4.49e-051901639IPR013151
Domain-

MATN3 MATN4 ITIH4 CPNE6 CLCA1 SEC24C

4.57e-057416363.40.50.410
DomainTMEM191C

TMEM191C TMEM191B

7.57e-0521632PF15194
DomainTMEM191B/C

TMEM191C TMEM191B

7.57e-0521632IPR028186
DomainMatrilin-3/4

MATN3 MATN4

7.57e-0521632IPR030765
DomainVWF_A

MATN3 MATN4 ITIH4 CPNE6 CLCA1 SEC24C

2.31e-04991636IPR002035
DomainIg_I-set

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 DCC IL1RL1 CNTN2

2.68e-041901638IPR013098
DomainI-set

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 DCC IL1RL1 CNTN2

2.68e-041901638PF07679
DomainDeath_domain

ANK2 ANK3 TNFRSF10D TNFRSF10B

3.27e-04381634IPR000488
DomainDEATH_DOMAIN

ANK2 ANK3 TNFRSF10D TNFRSF10B

3.27e-04381634PS50017
DomainIG

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 MCAM DCC SIRPD TIE1 NECTIN1 IL1RL1 CNTN2

3.34e-0442116312SM00409
DomainIg_sub

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 MCAM DCC SIRPD TIE1 NECTIN1 IL1RL1 CNTN2

3.34e-0442116312IPR003599
DomainC2-set_2

SIGLEC12 SIGLEC8 MCAM NECTIN1

4.40e-04411634PF08205
DomainCD80_C2-set

SIGLEC12 SIGLEC8 MCAM NECTIN1

4.40e-04411634IPR013162
DomainMatrilin_ccoil

MATN3 MATN4

4.49e-0441632SM01279
Domain-

MATN3 MATN4

4.49e-04416321.20.5.30
DomainMatrilin_ccoil

MATN3 MATN4

4.49e-0441632PF10393
DomainTNFR_10

TNFRSF10D TNFRSF10B

4.49e-0441632IPR020465
DomainMatrilin_coiled-coil_trimer

MATN3 MATN4

4.49e-0441632IPR019466
DomainVWFA

MATN3 MATN4 ITIH4 CPNE6 CLCA1

7.56e-04821635PS50234
DomainVWA

MATN3 MATN4 ITIH4 CPNE6 CLCA1

8.44e-04841635SM00327
DomainPH_BEACH

LYST LRBA

1.11e-0361632PF14844
DomainVWA

MATN3 MATN4 ITIH4 CLCA1

1.44e-03561634PF00092
DomainRNA_pol_II-bd

SCAF8 PCF11

1.54e-0371632IPR006903
Domain-

DCDC2 DCDC1

1.54e-03716323.10.20.230
DomainCTD_bind

SCAF8 PCF11

1.54e-0371632PF04818
DomainPInositol-4-P-5-kinase

PIP5K1C PIP5KL1

1.54e-0371632IPR023610
DomainDCX

DCDC2 RP1L1

1.54e-0371632PF03607
DomainIg-like_dom

SIGLEC12 BOC NRG1 SIGLEC8 FSTL4 MCAM DCC SIRPD TIE1 NECTIN1 IL1RL1 CNTN2

1.57e-0350316312IPR007110
DomainDEATH

ANK2 ANK3 TNFRSF10B

1.64e-03271633SM00005
DomainTNFR_NGFR_1

TNFRSF10D TNFRSF10B TNFRSF13B

2.02e-03291633PS00652
DomainTNFR_NGFR_2

TNFRSF10D TNFRSF10B TNFRSF13B

2.02e-03291633PS50050
DomainRPR

SCAF8 PCF11

2.05e-0381632SM00582
DomainPIPKc

PIP5K1C PIP5KL1

2.05e-0381632SM00330
Domain-

PIP5K1C PIP5KL1

2.05e-03816323.30.800.10
DomainPIP5K

PIP5K1C PIP5KL1

2.05e-0381632PF01504
DomainPIPK

PIP5K1C PIP5KL1

2.05e-0381632PS51455
DomainCID_dom

SCAF8 PCF11

2.05e-0381632IPR006569
DomainPInositol-4-P-5-kinase_N

PIP5K1C PIP5KL1

2.05e-0381632IPR027484
DomainPInositol-4-P-5-kinase_C

PIP5K1C PIP5KL1

2.05e-0381632IPR027483
DomainPH-BEACH_dom

LYST LRBA

2.05e-0381632IPR023362
Domain-

LYST LRBA

2.05e-03816322.30.29.40
DomainCID

SCAF8 PCF11

2.05e-0381632PS51391
DomainPH_BEACH

LYST LRBA

2.05e-0381632PS51783
Domain-

PIP5K1C PIP5KL1

2.05e-03816323.30.810.10
DomainPInositol-4-P-5-kinase_core

PIP5K1C PIP5KL1

2.05e-0381632IPR002498
DomainGlyco_hydro_47

MAN1C1 USF3

2.05e-0381632IPR001382
Domain-

SIGLEC12 BOC PLXNA3 NRG1 SIGLEC8 FSTL4 MCAM DCC SIRPD TIE1 PTPRZ1 NECTIN1 IL1RL1 CNTN2

2.05e-03663163142.60.40.10
DomainBEACH

LYST LRBA

2.62e-0391632PS50197
DomainBeach

LYST LRBA

2.62e-0391632PF02138
Domain-

LYST LRBA

2.62e-03916321.10.1540.10
DomainBeach

LYST LRBA

2.62e-0391632SM01026
DomainZU5

ANK2 ANK3

2.62e-0391632SM00218
DomainBEACH_dom

LYST LRBA

2.62e-0391632IPR000409
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 PLXNA3 SHROOM3 EPPK1 REPS1 KAT2A PIP5K1C LYST PCNX2 KMT2C THADA ZNF827 TLN1 ZNF516 ZNF500 KBTBD11 NINL CPSF1 COBL TANC1 LRBA HERC1 SNAPC4 SIPA1L2 ZNF839 HECTD1 ARAP1 AHNAK2

1.51e-1211051732835748872
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CCDC8 SHROOM3 ANK3 MCAM RFC3 TUFM PCF11 KIAA1671 THADA FAF2 SEC24C KBTBD11 PDS5A PEAK1 LRBA PCDH9 PCM1 RASAL2 ZC3HAV1

1.36e-087771731935844135
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCDC8 SHROOM3 INPP5F LYST KIAA1671 CEP89 PLEKHG3 STARD9 COBL TANC1 PEAK1 SIPA1L2 HECTD1 BICC1 PCM1 RASAL2 OTOG AHNAK2 ZC3HAV1

6.84e-088611731936931259
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

MAGED1 ANK3 FAAP20 KIAA1671 TANC1 PEAK1 LRBA SIPA1L2 RASAL2 AHNAK2 ZC3HAV1

9.59e-082631731134702444
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SHROOM3 ANK3 SCAF8 MAN1C1 TRPS1 ATP8B1 TSNAX STAT5B PCNX2 KIAA1671 THAP4 KMT2C THADA USF3 ZNF827 PLEKHG3 COBL TANC1 LRBA ZNF839 HECTD1 PCM1 ARAP1 INVS ZC3HAV1

1.06e-0714891732528611215
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DAB2 ZDBF2 KIAA1671 COBL TANC1 PEAK1 SIPA1L2 HECTD1 PCM1 RASAL2

1.07e-072091731036779422
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

CCDC8 ANK3 PKP4 DLGAP4 MCAM ERICH5 CEP89 COBL PEAK1 LRBA SIPA1L2 RASAL2 ZC3HAV1

2.18e-074211731336976175
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SHROOM3 EPPK1 MAGED1 ANK3 DAB2 TEX14 PIP5K1C KIAA1671 USF3 FAF2 TLN1 ARAP1 KPNB1

2.77e-074301731335044719
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SART3 CCDC8 SHROOM3 MAGED1 ANK2 ANK3 FAAP20 PKP4 TNFRSF10B NFS1 PCF11 EXOC5 THADA FAF2 SEC24C CEP89 TLN1 TANC1 LNPK PEAK1 SIPA1L2 PCM1 RASAL2 ZC3HAV1

3.99e-0714871732433957083
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A IQSEC3 ANK2 PCLO PKP4 DLGAP4 PRRT3 KBTBD11 LNPK SIPA1L2 PCM1

1.49e-063471731117114649
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

IQSEC3 FMR1 ANK2 ANK3 PCLO PKP4 DLGAP4 PIP5KL1 KBTBD11 RASAL2

1.61e-062811731028706196
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CACNA1A SART3 IQSEC3 FMR1 ANK2 ANK3 PCLO PKP4 DLGAP4 TUFM CPNE6 SEC24C PTPRZ1 TLN1 KBTBD11 TANC1 PEAK1 SIPA1L2 CNTN2 PCM1 RASAL2 KPNB1

2.80e-0614311732237142655
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MON2 FMR1 DCDC1 PKP4 TRPS1 PHRF1 KAT2A TNFRSF10B SCEL RFC3 TUFM ITIH4 KIAA1671 THADA ZNF827 CRNN TANC1 SIPA1L2 PCM1

3.33e-0611161731931753913
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SART3 EPPK1 FMR1 PHRF1 TUFM NUP205 SEC24C TLN1 CPSF1 PDS5A HECTD1 PCM1 ZC3HAV1 KPNB1

5.48e-066531731422586326
Pubmed

Adhesion molecule Amigo2 is involved in the fasciculation process of the fasciculus retroflexus.

DCC TH CNTN2

6.65e-068173335727300
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MON2 IQSEC3 SCAF8 DLGAP4 PIP5K1C FAF2 SEC24C STARD9 TLN1 COBL SIPA1L2

6.82e-064071731112693553
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

MON2 SART3 MAGED1 REPS1 DAB2 RFC3 TUFM NUP205 KIAA1671 EXOC5 THADA FAF2 PLEKHG3 TLN1 COBL PDS5A LNPK PCM1 AHNAK2 ZC3HAV1 KPNB1

1.07e-0514401732130833792
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

MON2 MAGED1 TSNAX RFC3 KIAA1671 EXOC5 FAF2 RLIM CPSF1 PDS5A POLR1B SIPA1L2 ZC3HAV1

1.19e-056061731336538041
Pubmed

The doublecortin gene family and disorders of neuronal structure.

DCDC2 DCDC1 RP1L1

1.41e-0510173320236041
Pubmed

Wnt1 Role in the Development of the Habenula and the Fasciculus Retroflexus.

DCC TH CNTN2

1.41e-0510173334722541
Pubmed

The evolving doublecortin (DCX) superfamily.

DCDC2 DCDC1 RP1L1

1.41e-0510173316869982
Pubmed

Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula.

DCC TH CNTN2

1.41e-0510173325033181
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SHROOM3 MAGED1 PKP4 INPP5F KIAA1671 CEP89 NINL SIPA1L2 HECTD1 PCM1 RASAL2

1.60e-054461731124255178
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

BOC FSTL4 MCAM DCC TIE1 NECTIN1 CNTN2

1.78e-05162173725826454
Pubmed

A protein interaction landscape of breast cancer.

CDKN1B EPPK1 FMR1 ANK3 PKP4 DAB2 KIAA1671 SEC24C TLN1 CRNN PDS5A PCM1 ZC3HAV1

1.91e-056341731334591612
Pubmed

Commissural axonal corridors instruct neuronal migration in the mouse spinal cord.

BOC DCC CNTN2

1.94e-0511173325960414
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

REPS1 ANK3 MIDEAS TUFM KIAA1671 KMT2C TLN1 PEAK1 LRBA PCM1 ZC3HAV1 KPNB1

2.17e-055491731238280479
Pubmed

Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions.

PIP5K1C TLN1

2.46e-052173215623515
Pubmed

Prognostic significance of DCC and p27Kip1 in colorectal cancer.

CDKN1B DCC

2.46e-052173215722793
Pubmed

FMRP regulates actin filament organization via the armadillo protein p0071.

FMR1 PKP4

2.46e-052173224062571
Pubmed

A new mouse model for autosomal recessive polycystic kidney disease.

ANK3 BICC1

2.46e-052173211944981
Pubmed

DR5 and DcR2 are expressed in human lumbar intervertebral discs.

TNFRSF10D TNFRSF10B

2.46e-052173219730199
Pubmed

Silencing of a targeted protein in in vivo platelets using a lentiviral vector delivering short hairpin RNA sequence.

ITGA2B TLN1

2.46e-052173217872456
Pubmed

GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations.

PCLO BICC1

2.46e-052173226391493
Pubmed

Importin β1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells.

TNFRSF10B KPNB1

2.46e-052173222020938
Pubmed

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

ANK2 ANK3

2.46e-052173211781319
Pubmed

Structural basis of diverse membrane target recognitions by ankyrins.

ANK2 ANK3

2.46e-052173225383926
Pubmed

A circular RNA produced by LRBA promotes cirrhotic mouse liver regeneration through facilitating the ubiquitination degradation of p27.

CDKN1B LRBA

2.46e-052173237208938
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SHROOM3 EPPK1 FMR1 SCAF8 DNAH2 RFC3 ARHGEF15 ITIH4 NUP205 SEC24C CPSF1 COBL TRIM47 PCDH9

2.71e-057541731435906200
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A IQSEC3 SHROOM3 MAGED1 FMR1 ANK2 ANK3 PKP4 DLGAP4 ARMCX4 ITIH4 SEC24C ZNF516 PCM1 RASAL2 KPNB1

2.76e-059631731628671696
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

SHROOM3 ANK3 PKP4 EPS8L1 SCEL KIAA1671 TLN1 NECTIN1 PALM3 TANC1 PEAK1 ZC3HAV1

2.86e-055651731225468996
Pubmed

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

EPPK1 MAGED1 FMR1 RFC3 TUFM NUP205 SEC24C ZC3HAV1 KPNB1

3.09e-05315173926777405
Pubmed

Human transcription factor protein interaction networks.

CCDC8 MAGED1 SCAF8 TNIP2 TRPS1 KAT2A MIDEAS STAT5B NUP205 PCF11 KIAA1671 KMT2C ZNF516 RLIM CPSF1 PDS5A HERC1 L3MBTL3 PCM1 ZC3HAV1

3.15e-0514291732035140242
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

NRG1 SHROOM3 EPPK1 SCAF8 RFC3 PCF11 EXOC5 SEC24C TLN1 CPSF1 ARAP1 KPNB1

3.81e-055821731220467437
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

EPPK1 MCAM ZDBF2 TLN1 TANC1 PCM1 AHNAK2 ZC3HAV1

4.59e-05256173833397691
Pubmed

Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer.

PCLO TUFM FAF2

5.27e-0515173331903119
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

EPPK1 MAGED1 REPS1 PKP4 PIP5K1C ARHGEF15 NUP205 KIAA1671 PLEKHG3 TLN1 CPSF1 COBL PDS5A PEAK1 ARAP1

5.84e-059161731532203420
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MON2 CACNA1A SART3 IQSEC3 MAGED1 FMR1 ANK2 ANK3 PCLO DLGAP4 ZDBF2 NFS1 NECTIN1 LNPK PEAK1 SIPA1L2 PCM1

5.86e-0511391731736417873
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SART3 SHROOM3 MAGED1 REPS1 SCAF8 PKP4 TRPS1 PHRF1 KAT2A TUFM PCF11 KIAA1671 KMT2C PLEKHG3 TLN1 PALM3 PDS5A POLR1B TANC1 ZC3HAV1

6.00e-0514971732031527615
Pubmed

Coronary veins determine the pattern of sympathetic innervation in the developing heart.

NRG1 TH NGF

6.46e-0516173323462468
Pubmed

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions.

PIP5K1C TLN1

7.36e-053173212422220
Pubmed

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3.

ITGA2B TLN1

7.36e-053173218573917
Pubmed

Talin-driven inside-out activation mechanism of platelet αIIbβ3 integrin probed by multimicrosecond, all-atom molecular dynamics simulations.

ITGA2B TLN1

7.36e-053173224677266
Pubmed

LncRNA LIMp27 Regulates the DNA Damage Response through p27 in p53-Defective Cancer Cells.

CDKN1B LINC01356

7.36e-053173236638271
Pubmed

Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels.

CACNA1A ANK2

7.36e-053173231477143
Pubmed

Heterogeneous requirement of NGF for sympathetic target innervation in vivo.

TH NGF

7.36e-053173214736860
Pubmed

NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution.

ITGA2B TLN1

7.36e-053173211412103
Pubmed

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

ANK2 ANK3

7.36e-053173215611082
Pubmed

A novel receptor for Apo2L/TRAIL contains a truncated death domain.

TNFRSF10D TNFRSF10B

7.36e-05317329382840
Pubmed

Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis.

TNFRSF10D TNFRSF10B

7.36e-053173216319225
Pubmed

The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.

ITGA2B TLN1

7.36e-053173220947017
Pubmed

Possible involvement of mitogen- and stress-activated protein kinase 1, MSK1, in metaphase-II arrest through phosphorylation of EMI2 in mouse oocytes.

FAT2 FBXO43

7.36e-053173221924255
Pubmed

Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.

CACNA1A TH

7.36e-053173232154672
Pubmed

TA205, an anti-talin monoclonal antibody, inhibits integrin-talin interaction.

ITGA2B TLN1

7.36e-053173216546176
Pubmed

Ubiquitin specific peptidase 5 regulates colorectal cancer cell growth by stabilizing Tu translation elongation factor.

USP13 TUFM

7.36e-053173231281542
Pubmed

Uncommon somatic mutations in metastatic NUT midline carcinoma.

DCC KMT2C

7.36e-053173228967088
Pubmed

Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting.

CACNA1A ANK2

7.36e-053173224394417
Pubmed

Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain.

PIP5K1C TLN1

7.36e-053173218638481
Pubmed

Direct binding of the platelet integrin alphaIIbbeta3 (GPIIb-IIIa) to talin. Evidence that interaction is mediated through the cytoplasmic domains of both alphaIIb and beta3.

ITGA2B TLN1

7.36e-05317328663236
Pubmed

Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain.

PIP5K1C TLN1

7.36e-053173212782621
Pubmed

Heterogeneous intracellular TRAIL-receptor distribution predicts poor outcome in breast cancer patients.

TNFRSF10D TNFRSF10B

7.36e-053173231183506
Pubmed

Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.

TNFRSF10D TNFRSF10B

7.36e-053173216980609
Pubmed

Abnormal expression of tyrosine hydroxylase immunoreactivity in cerebellar cortex of ataxic mutant mice.

CACNA1A TH

7.36e-053173210350535
Pubmed

Human ankyrins and their contribution to disease biology: An update.

ANK2 ANK3

7.36e-053173233410423
Pubmed

Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration.

PIP5K1C TLN1

7.36e-053173223572508
Pubmed

Alternating array of tyrosine hydroxylase and heat shock protein 25 immunopositive Purkinje cell stripes in zebrin II-defined transverse zone of the cerebellum of rolling mouse Nagoya.

CACNA1A TH

7.36e-053173220462503
Pubmed

Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.

ANK2 ANK3

7.36e-053173234289389
Pubmed

COBL, MKX and MYOC Are Potential Regulators of Brown Adipose Tissue Development Associated with Obesity-Related Metabolic Dysfunction in Children.

MYOC COBL

7.36e-053173236834493
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SART3 SHROOM3 PHRF1 INPP5F NUP205 KMT2C ZNF516 KBTBD11 NINL L3MBTL3 ARAP1

7.48e-055291731114621295
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MON2 CCDC8 ANK3 PKP4 TRPS1 MCAM PCF11 KIAA1671 CEP89 PTPRZ1 CPSF1 TANC1 PEAK1 HERC1 L3MBTL3 KPNB1

7.59e-0510491731627880917
Pubmed

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.

FMR1 SCAF8 RFC3 HECTD1 ZC3HAV1

7.64e-0587173533711283
Pubmed

Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution.

NRG1 TH CNTN2

7.81e-0517173321435555
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

NRG1 MAGED1 DLGAP4 ATP8B1 TNFRSF10D TNFRSF10B SLC47A2 NUP205 THADA FAF2 PDS5A LRBA HERC1 TRIM47 PCDH9 BICC1

8.66e-0510611731633845483
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SHROOM3 TROAP FAAP20 PKP4 NUP205 KIAA1671 TLN1 NINL COBL TANC1 SIPA1L2 PCM1 ZC3HAV1 KPNB1

1.01e-048531731428718761
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

ANK3 PKP4 DAB2 MCAM TNFRSF10B PIP5K1C PEAK1 RASAL2 ZC3HAV1

1.22e-04377173938117590
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

MAGED1 FMR1 TNIP2 DLGAP4 CIR1 IGFBP6 CEP89 NINL COBL L3MBTL3 RIC3

1.23e-045601731121653829
Pubmed

Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function.

CDKN1B TNFRSF10D TNFRSF10B

1.30e-0420173333323382
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

DAB2 MCAM ZDBF2 TLN1 TANC1 LNPK LRBA PCM1 AHNAK2 ZC3HAV1 KPNB1

1.40e-045681731137774976
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

NRG1 ANK2 PKP4 MCAM NECTIN1 CRNN COBL TANC1 PEAK1 LRBA RASAL2

1.42e-045691731130639242
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

CDKN1B SCAF8 PHRF1 DAB2 PCF11 SEC24C ZNF516 CPSF1 SNAPC4 ANXA9 MN1 PCM1 ZC3HAV1

1.44e-047741731315302935
Pubmed

Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling.

TH NGF

1.47e-044173229381137
Pubmed

DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer Cells.

KAT2A TNFRSF10B

1.47e-044173225770212
Pubmed

Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.

PIP5K1C TLN1

1.47e-044173218188447
Pubmed

Human-specific elimination of epithelial Siglec-XII suppresses the risk of inflammation-driven colorectal cancers.

SIGLEC12 SIGLEC8

1.47e-044173238990656
Pubmed

Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane.

TNFRSF10B ARAP1

1.47e-044173218165900
Pubmed

TRAIL receptor deficiency sensitizes mice to dextran sodium sulphate-induced colitis and colitis-associated carcinogenesis.

TNFRSF10D TNFRSF10B

1.47e-044173224117005
Pubmed

Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm.

SIGLEC12 SIGLEC8

1.47e-044173227494323
Pubmed

Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response.

SIGLEC12 SIGLEC8

1.47e-044173237460871
Pubmed

Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo.

SIGLEC12 SIGLEC8

1.47e-044173224391502
Pubmed

Membrane expression of TRAIL receptors DR4, DR5, DcR1 and DcR2 in the normal endometrium, atypical endometrial hyperplasia and endometrioid adenocarcinoma: a tissue microarray study.

TNFRSF10D TNFRSF10B

1.47e-044173223584885
InteractionTOP3B interactions

MON2 PLXNA3 SHROOM3 EPPK1 FMR1 REPS1 KAT2A TSNAX PIP5K1C LYST TUFM PCNX2 KMT2C THADA ZNF827 TLN1 ZNF516 ZNF500 KBTBD11 NINL CPSF1 COBL TANC1 LRBA HERC1 SNAPC4 SIPA1L2 ZNF839 HECTD1 ARAP1 AHNAK2 ZC3HAV1

1.96e-07147016232int:TOP3B
InteractionSTX7 interactions

MON2 CCDC8 ANK3 DAB2 MCAM EPS8L1 INPP5F ERICH5 EXOC5 CEP89 LNPK PEAK1 LRBA SIPA1L2 CX3CL1 RASAL2 RIC3 ZC3HAV1

6.23e-0665916218int:STX7
InteractionYWHAH interactions

CDKN1B CCDC8 SHROOM3 EPPK1 INPP5F LYST KIAA1671 CEP89 PLEKHG3 STARD9 NINL COBL TANC1 PEAK1 LRBA HERC1 SIPA1L2 HECTD1 BICC1 PCM1 RASAL2 OTOG AHNAK2 ZC3HAV1

8.16e-06110216224int:YWHAH
InteractionEZR interactions

REPS1 ANK2 ANK3 MCAM TNFRSF10B DCC ARHGEF15 KIAA1671 TIE1 RLIM FBXO43 COBL TANC1 PEAK1 LRBA RASAL2

1.04e-0555316216int:EZR
GeneFamilyDoublecortin superfamily

DCDC2 DCDC1 RP1L1

2.84e-051011431369
GeneFamilyImmunoglobulin like domain containing

BOC FSTL4 MCAM DCC TIE1 NECTIN1 IL1RL1 CNTN2

3.06e-051931148594
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SIGLEC12 BOC NRG1 FSTL4 DCC IL1RL1 CNTN2

7.22e-051611147593
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PKP4 ARMCX4 THADA KPNB1

1.53e-04431144409
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF10D TNFRSF10B TNFRSF13B

7.92e-04291143782
GeneFamilyAnkyrin repeat domain containing

ANKK1 ANK2 ANK3 TANC1 HECTD1 ARAP1 INVS

8.62e-042421147403
GeneFamilyWD repeat domain containing|BEACH domain containing

LYST LRBA

1.38e-03911421230
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SIGLEC12 MCAM NECTIN1

2.04e-03401143592
GeneFamilyNon-clustered protocadherins

PCDH12 PCDH9

2.50e-0312114221
GeneFamilyFibronectin type III domain containing

BOC DCC TIE1 PTPRZ1 CNTN2

3.45e-031601145555
GeneFamilyAdenosine receptors|V-set domain containing

SIGLEC12 SIGLEC8 MCAM SIRPD NECTIN1

3.73e-031631145590
GeneFamilyCadherin related

CDH23 FAT2

5.04e-0317114224
CoexpressionAIZARANI_LIVER_C39_EPCAM_POS_BILE_DUCT_CELLS_4

NRG1 DCDC2 PKP4 MCAM TNFRSF10B COBL TRIM47 CX3CL1 BICC1

3.40e-061841709M39135
CoexpressionGSE20727_CTRL_VS_H2O2_TREATED_DC_DN

ANK3 TNIP2 KAT2A TNFRSF10B MIDEAS LYST THADA L3MBTL3 ZC3HAV1

5.69e-061961709M9243
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

CERKL DCDC2 SHROOM3 EPPK1 MATN4 TSNAX TNFRSF10B SLC47A2 PCNX2 IGFBP6 PRRT3 NGF TRIM47 RIC3

1.35e-0554417014M1936
CoexpressionLAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE

DCDC2 SHROOM3 ANK3 KMT2C LRBA PCDH9 BICC1 RASAL2

1.66e-051711708M39234
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

CERKL DCDC2 SHROOM3 EPPK1 MATN4 TNFRSF10D TSNAX TNFRSF10B PCNX2 IGFBP6 PRRT3 NGF TRIM47 RIC3

2.44e-0557417014MM820
CoexpressionAIZARANI_LIVER_C20_LSECS_3

USP13 DAB2 MCAM TNFRSF10D TNFRSF10B TIE1 TANC1 IL1RL1 PEAK1 HERC1

2.44e-0529517010M39121
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_DN

MAGED1 ANK2 PCLO TNFRSF10D PCDH12 CLCA1 TIE1 PTPRZ1

4.11e-051941708M8864
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_LATE_MESOTHELIAL_CELL

SHROOM3 PCLO EPS8L1 SCEL APOL1 IGFBP6 PLEKHG3 TMEM191B SBSPON COBL ANXA9 MN1 RIC3 AHNAK2 ZC3HAV1

5.84e-0570417015M45672
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK2 ANK3 PCLO PKP4 TRPS1 NINL COBL LRBA BICC1

3.10e-1019617211eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellBasal_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

NRG1 EPPK1 FAT2 IGFBP6 PTPRZ1 PLEKHG3 NECTIN1 CNTN2 AHNAK2

1.79e-081661729aea2ae12e4746149ebc6da063ef694381c098f80
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK3 PCLO PKP4 NINL COBL LRBA BICC1

6.56e-0819317293866667dd221612589ae50f5c52f73a183a49ce6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK3 PCLO PKP4 NINL COBL LRBA BICC1

6.86e-08194172993c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK3 PCLO PKP4 NINL COBL LRBA BICC1

7.16e-0819517296477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BOC IQSEC3 MATN3 MATN4 ZNF497 PTPRZ1 MN1 AHNAK2

4.75e-071781728a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK3 DCC SLC47A2 SBSPON NINL BICC1

6.63e-071861728b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 ATP8B1 SLFN5 TNFRSF10B PCDH12 ARHGEF15 KIAA1671 TIE1

8.43e-0719217280aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK3 PCLO NINL COBL LRBA BICC1

8.76e-07193172882e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK3 SLC47A2 ZNF827 NINL COBL BICC1

9.11e-0719417287002937e8903e037332a215d00fbc7c7843b33f2
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 PCDH12 ARHGEF15 KIAA1671 TIE1 TANC1 SIPA1L2 CX3CL1

9.11e-07194172843f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 PCDH12 ARHGEF15 KIAA1671 TIE1 TANC1 SIPA1L2 CX3CL1

9.11e-0719417281d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 ATP8B1 PCDH12 ARHGEF15 KIAA1671 TIE1 TANC1 CX3CL1

9.11e-07194172858f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 ATP8B1 PCDH12 ARHGEF15 KIAA1671 TIE1 TANC1 CX3CL1

9.11e-071941728bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

DAB2 ATP8B1 SLFN5 ARHGEF15 KIAA1671 TIE1 PEAK1 RASAL2

9.47e-0719517286b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK2 ANK3 PKP4 PLEKHG3 LRBA BICC1

9.84e-071961728c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK3 PCLO NINL COBL LRBA BICC1

9.84e-0719617286ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC ARHGEF15 KIAA1671 TIE1 STARD9 PEAK1 MN1 RASAL2

1.02e-061971728cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANK2 ANK3 IGFBP6 PTPRZ1 SBSPON COBL PCDH9 BICC1

1.02e-061971728b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NWD1 DNAH2 EPS8L1 TMPRSS11F CLCA1 PTPRZ1 CRNN ANXA9

1.10e-06199172860919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell(2)_Fibroblasts|World / Cell class and subclass of bone marrow stroma cells in homeostatis

BOC ANK2 MYOC TRPS1 IGFBP6 TRIM47 MN1 AHNAK2

1.10e-061991728777423b413376b0d3fbd92ff51dd0133fb54d293
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NWD1 DNAH2 EPS8L1 TMPRSS11F CLCA1 PTPRZ1 CRNN ANXA9

1.10e-0619917286aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM3 ANK3 PCLO PKP4 ATP8B1 KIAA1671 COBL TANC1

1.14e-062001728d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellHealthy-CD4+_T_activated|World / disease group, cell group and cell class

SLFN5 TEX14 ARMCX4 ARHGEF15 PCNX2 FBXO43 CNTN2

1.24e-061401727407691970ec72a3afb45e431cf48814546b8acff
ToppCellHealthy-CD4+_T_activated|Healthy / disease group, cell group and cell class

SLFN5 TEX14 ARMCX4 ARHGEF15 PCNX2 FBXO43 CNTN2

1.56e-06145172745e8089fdf7d6f69b383816d8945e39fba24c873
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

NRG1 ANK2 MATN3 SCEL SBSPON COBL BICC1

3.27e-061621727ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BOC DCDC2 FSTL4 NECTIN1 COBL TANC1 KCNH5

3.41e-0616317271e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BOC DCDC2 FSTL4 NECTIN1 COBL TANC1 KCNH5

3.41e-061631727431221a41d396b09170476179590eaf8a55266d8
ToppCell356C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SIGLEC8 DNAH2 TIE1 COBL IL1RL1 KLHL34 RIC3

3.55e-061641727b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCell356C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SIGLEC8 DNAH2 TIE1 COBL IL1RL1 KLHL34 RIC3

3.55e-061641727f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 SMOC1 DCC TIE1 CPSF1 POLR1B TRIM47

3.69e-06165172762457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK2 ANK3 INPP5F PTPRZ1 SBSPON SIPA1L2 PCDH9

4.16e-06168172788c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

NRG1 SHROOM3 ANK3 SCEL COBL TANC1 RASAL2

4.50e-061701727e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCDC2 EPPK1 SMOC1 SBSPON NGF TRIM47 BICC1

4.85e-061721727a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCDC2 EPPK1 SMOC1 SBSPON NGF TRIM47 BICC1

4.85e-0617217270a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC SLC46A2 DCDC2 SHROOM3 ANK3 TEX14 MFSD2A

6.31e-061791727fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLFN5 PCDH12 ARHGEF15 KIAA1671 TIE1 SIPA1L2 CX3CL1

7.29e-061831727e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCAM SLFN5 PCDH12 ARHGEF15 KIAA1671 CLCA1 TIE1

7.55e-061841727fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM SLFN5 PCDH12 ARHGEF15 KIAA1671 CLCA1 TIE1

7.55e-061841727ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCAM SLFN5 PCDH12 ARHGEF15 KIAA1671 CLCA1 TIE1

7.55e-0618417271d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCAM SLFN5 PCDH12 ARHGEF15 KIAA1671 CLCA1 TIE1

7.55e-06184172776caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM SLFN5 PCDH12 ARHGEF15 KIAA1671 CLCA1 TIE1

7.55e-0618417271fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM SLFN5 PCDH12 ARHGEF15 KIAA1671 CLCA1 TIE1

7.55e-0618417272467207aaea307873ab286f89cfc7668a227a694
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKP4 TNFRSF10D PCDH12 ARHGEF15 CPNE6 TIE1 RASAL2

7.82e-0618517270ab1be455f2cd883c9d1522ca78112c37833352e
ToppCellVE-CD4-CD8_2|VE / Condition, Cell_class and T cell subcluster

DCDC2 MAN1C1 ITGA2B ZNF497 SBSPON PRRT3

8.01e-0612217266745035feaf807b6a6b9537ac9d5ee0e000196eb
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG1 EPPK1 SCEL FAT2 ZNF827 SYTL5 PTPRZ1

8.99e-061891727783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ATP8B1 NUP205 PCNX2 EXOC5 USF3 L3MBTL3 ARAP1

8.99e-061891727c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM SLFN5 TNFRSF10B PCDH12 ARHGEF15 CLCA1 TIE1

8.99e-061891727ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

DAB2 MCAM SLFN5 TNFRSF10B PCDH12 ARHGEF15 TIE1

8.99e-0618917279a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 MCAM SLFN5 TNFRSF10B PCDH12 ARHGEF15 TIE1

8.99e-061891727f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM SLFN5 TNFRSF10B PCDH12 ARHGEF15 CLCA1 TIE1

8.99e-061891727e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TNFRSF10B PCDH12 ARHGEF15 KIAA1671 TIE1 SIPA1L2 CX3CL1

8.99e-0618917275d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 MCAM SLFN5 TNFRSF10B PCDH12 ARHGEF15 TIE1

8.99e-061891727e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG1 EPPK1 SCEL FAT2 ZNF827 SYTL5 PTPRZ1

8.99e-06189172788b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCellfacs-Trachea-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCAM SLFN5 TNFRSF10B PCDH12 ARHGEF15 CLCA1 TIE1

8.99e-061891727f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 MCAM SLFN5 TNFRSF10B PCDH12 ARHGEF15 TIE1

8.99e-0618917275559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCAM SLFN5 ARMCX4 ARHGEF15 KIAA1671 TIE1 TRIM47

8.99e-0618917271e1afa66b32ae752c0a42b02b80f10205464569c
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRG1 EPPK1 SCEL FAT2 ZNF827 SYTL5 PTPRZ1

9.31e-06190172747e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRG1 EPPK1 SCEL FAT2 ZNF827 SYTL5 PTPRZ1

9.31e-061901727261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

PCLO EPS8L1 SCEL ERICH5 SBSPON ANXA9 KCNH5

9.31e-061901727d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCDH12 ARHGEF15 KIAA1671 TIE1 TANC1 CX3CL1 RASAL2

9.31e-061901727474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 DCC SLC47A2 KIAA1671 NINL COBL BICC1

9.63e-0619117273c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 DCC SLC47A2 KIAA1671 NINL COBL BICC1

9.63e-0619117271c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FSTL4 PCDH12 ARHGEF15 KIAA1671 TIE1 SIPA1L2 CX3CL1

9.63e-0619117271de0bdfd13bd930691564c2673f2e66393bc0255
ToppCellBasal_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

FAT2 IGFBP6 PTPRZ1 NECTIN1 CX3CL1 AHNAK2 KCNH5

9.63e-061911727a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

PKP4 CDH23 TNFRSF10D ARHGEF15 KIAA1671 TIE1 CX3CL1

9.63e-061911727c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellhuman_hepatoblastoma-Endothelial_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

BOC USP13 MCAM TNFRSF10D ARHGEF15 TIE1 SIPA1L2

9.96e-061921727e09f609fed033a25baacaf4a07bbbae1076da366
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 MCAM PCDH12 ARHGEF15 TIE1 PEAK1 RASAL2

9.96e-0619217272bfac6b3956265205ca47d06888851ed68b65999
ToppCellControl-B_intermediate-10|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

BOC ANK2 ANK3 INPP5F TLN1 KBTBD11 PCDH9

9.96e-061921727224bd958369ba8fa0d7be2126f7dc61c9f6ac19d
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 MCAM PCDH12 ARHGEF15 TIE1 PEAK1 RASAL2

9.96e-061921727d525f7f088a53110912600a7c9f6d33b9270d534
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 MCAM SLFN5 PCDH12 ARHGEF15 CLCA1 TIE1

1.03e-0519317275d42979d811ee13a07dee08a3743a90776017cb4
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 MCAM SLFN5 PCDH12 ARHGEF15 CLCA1 TIE1

1.03e-05193172795e64b9580d30c28702639a043a8b72ce1cadeb6
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 MCAM SLFN5 PCDH12 ARHGEF15 CLCA1 TIE1

1.03e-05193172797c0730aad9135ac681250b3871cc094a28f80a7
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL NWD1 DCDC1 ANK3 DNAH2 PTPRZ1 AHNAK2

1.03e-051931727ea345d34440b25f65358a53dc72831998d1c3620
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 ATP8B1 PCDH12 ARHGEF15 KIAA1671 TIE1 RASAL2

1.03e-051931727af5108260783e69a7d67896c5bf64f862525926d
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-AT1-AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM191C SCEL ZNF497 SYTL5 PRRT3 PALM3

1.05e-051281726082b3dc312b033c9b21cf73499009a1dc049ee2b
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 MCAM PCDH12 ARHGEF15 TIE1 PEAK1 RASAL2

1.07e-051941727c8b9551b93a5aed62154b487db90130604a6125c
ToppCellMesenchymal_cells-Arteriolar_fibro.|World / Lineage and Cell class

BOC ANK2 MYOC IGFBP6 MN1 BICC1 AHNAK2

1.07e-051941727c1e8923a50b4138a1e4c054c0c17b7f7122aa8a9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 SHROOM3 ANK3 PCLO NINL COBL BICC1

1.07e-0519417275eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKP4 ATP8B1 ARHGEF15 KIAA1671 TIE1 SIPA1L2 RASAL2

1.07e-0519417270b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYOC MCAM PCDH12 ARHGEF15 KIAA1671 TIE1 CX3CL1

1.10e-0519517273826bfafe85f8aa9a508202ceb2b02e81b090498
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A MAGED1 PCLO KMT2C ZNF516 HERC1 PCM1

1.10e-0519517273e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A MAGED1 PCLO KMT2C ZNF516 HERC1 PCM1

1.10e-0519517277796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 MCAM ARHGEF15 KIAA1671 CLCA1 TIE1 TANC1

1.14e-051961727b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 MCAM ARHGEF15 KIAA1671 CLCA1 TIE1 TANC1

1.14e-051961727ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 MCAM ARHGEF15 KIAA1671 CLCA1 TIE1 TANC1

1.14e-051961727039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC ARHGEF15 TIE1 STARD9 PEAK1 SIPA1L2 RASAL2

1.14e-051961727ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 ARMCX4 ARHGEF15 TIE1 TANC1 PEAK1 RASAL2

1.18e-051971727deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BOC NRG1 MCAM SMOC1 SBSPON NGF BICC1

1.18e-051971727f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANK3 ZDBF2 KMT2C IL1RL1 LRBA HERC1 PCM1

1.18e-05197172757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 ARMCX4 ARHGEF15 TIE1 TANC1 PEAK1 RASAL2

1.18e-051971727a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BOC MYOC SMOC1 SBSPON MN1 PCDH9 BICC1

1.18e-0519717273fe665c0277d091290b63f0dd24c0c6536a45309
ToppCell(3)_Chondrocytes-(34)_Chondro-progen|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

BOC ANK2 MYOC SMOC1 IGFBP6 MN1 AHNAK2

1.18e-051971727012c49a57f9c2a3dfa988cd3882c8c6b7ef3a5ad
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MATN3 PKP4 ATP8B1 PCDH12 ARHGEF15 MFSD2A TIE1

1.18e-0519717279e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC ARHGEF15 KIAA1671 TIE1 STARD9 PEAK1 RASAL2

1.18e-051971727412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAH2 EPS8L1 TMPRSS11F CLCA1 PTPRZ1 CRNN ANXA9

1.22e-0519817276712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

TDRD9 EPS8L1 SCEL CLCA1 PTPRZ1 CRNN ANXA9

1.22e-051981727e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

TDRD9 EPS8L1 SCEL CLCA1 PTPRZ1 CRNN ANXA9

1.22e-051981727ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

ANK2 DAB2 SMOC1 IGFBP6 TRIM47 MN1 AHNAK2

1.22e-0519817279f9dcf23ffb333105263132d87b90095642294cf
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 ARMCX4 ARHGEF15 TIE1 TANC1 PEAK1 RASAL2

1.22e-051981727f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
DiseaseR-6-hydroxywarfarin measurement

SHROOM3 NWD1 TRPS1 DNAH2 LRBA PCDH9

4.08e-051141626EFO_0803327
Diseasered blood cell density measurement

NRG1 SHROOM3 DCDC1 PKP4 TRPS1 DNAH2 ATP8B1 TUFM NUP205 ZNF827 NGF PALM3 TNFRSF13B L3MBTL3 CNTN2

1.09e-0488016215EFO_0007978
Diseasenon-high density lipoprotein cholesterol measurement

CACNA1A PLXNA3 REPS1 TRPS1 ATP8B1 MIDEAS ARHGEF15 THADA ZNF846 PDS5A ANXA9 L3MBTL3 KPNB1

1.65e-0471316213EFO_0005689
Diseaserenal system measurement

SHROOM3 DCDC1 SCAF8

1.73e-04201623EFO_0004742
DiseaseIntellectual Disability

IQSEC3 FMR1 DCC PCDH12 KMT2C TH MFSD2A RLIM LNPK MN1

1.92e-0444716210C3714756
Diseasesusceptibility to bacterial meningitis measurement

CERKL NRG1 ANK3 NECTIN1

1.93e-04521624EFO_0008411
Diseaseautism spectrum disorder

NWD1 PKP4 DCC RP1L1 ANXA9 PCDH9

2.30e-041561626EFO_0003756
DiseaseAbnormality of the cerebellum

LNPK MN1

2.96e-0451622C1866129
Diseasewithdrawal disorder (biomarker_via_orthology)

FMR1 TH

2.96e-0451622DOID:0060001 (biomarker_via_orthology)
Diseasecyclin-dependent kinase inhibitor 1b measurement

CDKN1B ITIH4

2.96e-0451622EFO_0020298
DiseaseBipolar Disorder

ANKK1 CACNA1A NRG1 ANK3 PCLO TSNAX ITIH4 TH SEC24C STARD9

3.22e-0447716210C0005586
Diseasechronic kidney disease

NRG1 SHROOM3 DCDC1 DAB2 APOL1 CEP89 L3MBTL3

3.33e-042351627EFO_0003884
DiseaseFEV/FEC ratio

BOC SCAF8 TNIP2 TRPS1 CDH23 IL17RC DCC RFC3 THADA SBSPON ZNF516 IL1RL1 HERC1 L3MBTL3 MN1 CNTN2 ARAP1

4.42e-04122816217EFO_0004713
Diseasecreatinine measurement, glomerular filtration rate

SHROOM3 DCDC1 DAB2 THADA ANXA9

4.79e-041171625EFO_0004518, EFO_0005208
Diseaseganglion cell inner plexiform layer thickness measurement

TDRD9 COBL INVS

4.81e-04281623EFO_0600005
Diseaseaspartate aminotransferase measurement

NRG1 SHROOM3 DNAH2 FSTL4 DAB2 ATP8B1 TNFRSF10B INPP5F ZNF827 NGF LRBA ANXA9 L3MBTL3 CNTN2

4.86e-0490416214EFO_0004736
Diseasesystemic lupus erythematosus

CDKN1B SHROOM3 TNIP2 MFSD6 PHRF1 DAB2 CDH23 LYST SIRPD TNFRSF13B CX3CL1 L3MBTL3 AHNAK2

4.90e-0479916213MONDO_0007915
Diseaseserum gamma-glutamyl transferase measurement

REPS1 ATP8B1 TNFRSF10B ARHGEF15 THADA ZNF827 TLN1 RP1L1 PALM3 LRBA ANXA9 SIPA1L2 L3MBTL3 BICC1

5.42e-0491416214EFO_0004532
DiseaseParkinsonian Disorders

LYST TH NGF

5.91e-04301623C0242422
DiseaseHelicobacter Infections

CDKN1B PTPRZ1

6.18e-0471622C0079487
DiseaseEsophageal carcinoma

DCC CRNN

6.18e-0471622C0152018
Diseasetestosterone measurement

SHROOM3 DCDC1 ANK2 ANK3 DLGAP4 TRPS1 DNAH2 TNFRSF10B MIDEAS ARHGEF15 THADA PALM3 TNFRSF13B ANXA9 L3MBTL3 ARAP1 KPNB1

6.74e-04127516217EFO_0004908
Diseaseplatelet crit

CDKN1B FAAP20 MFSD6 MCAM ITGA2B NUP205 SIRPD THADA TLN1 TNFRSF13B POLR1B MN1 RASAL2 ZC3HAV1

8.05e-0495216214EFO_0007985
Diseasesialic acid-binding Ig-like lectin 6 measurement

SIGLEC12 SIGLEC8

8.21e-0481622EFO_0008285
Diseasecreatinine measurement, chronic kidney disease

SHROOM3 DAB2 ANXA9

9.34e-04351623EFO_0003884, EFO_0004518
Diseaseunderweight body mass index status

ANK2 DCC

1.05e-0391622EFO_0005936
DiseaseDisorder of eye

CERKL NR2E3 MYOC CDH23 SMOC1 INVS

1.16e-032121626C0015397
Diseasemembranoproliferative glomerulonephritis (biomarker_via_orthology)

CDKN1B MYOC

1.31e-03101622DOID:2920 (biomarker_via_orthology)
Diseaseinfluenza A (H1N1)

MAN1C1 TRPS1 TMPRSS11F L3MBTL3

1.37e-03871624EFO_1001488
Diseasehematocrit

NRG1 NR2E3 SHROOM3 DCDC1 TRPS1 DNAH2 ATP8B1 ARHGEF15 TH MFSD2A TIE1 TNFRSF13B L3MBTL3 BICC1

1.42e-03101116214EFO_0004348
DiseaseChagas cardiomyopathy

NRG1 TRAV3 SIGLEC8

1.82e-03441623EFO_0005529
DiseaseNeurogenic Inflammation

MCAM NGF

1.91e-03121622C0600467
Diseasepersulfide dioxygenase ETHE1, mitochondrial measurement

NRG1 ITIH4

1.91e-03121622EFO_0008258
Diseasegranulins measurement

CDH23 ITGA2B

1.91e-03121622EFO_0008141
Diseasepapillary thyroid carcinoma

NRG1 PCNX2

1.91e-03121622EFO_0000641
Diseaserhinitis (is_marker_for)

NGF IL1RL1 CX3CL1

2.07e-03461623DOID:4483 (is_marker_for)
Diseasehair colour measurement

NRG1 SHROOM3 DLGAP4 TRPS1 SCEL LYST THADA NINL SIPA1L2 L3MBTL3

2.20e-0361516210EFO_0007822
DiseaseCommon variable immunodeficiency

TNFRSF13B LRBA

2.25e-03131622cv:C0009447
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

ITIH4 PTPRZ1

2.25e-03131622DOID:332 (biomarker_via_orthology)
Diseaseocular hypertension, response to triamcinolone acetonide

CDH23 IL17RC TEX14

2.49e-03491623EFO_0006954, EFO_1001069
Diseasedepressive symptom measurement

ANKK1 CACNA1A PCLO DCC ITIH4 LNPK HERC1 PCDH9

2.53e-034261628EFO_0007006
DiseasePneumoconiosis

CDH23 PTPRZ1

2.61e-03141622C0032273
DiseaseBagassosis

CDH23 PTPRZ1

2.61e-03141622C0004681
DiseaseMental Depression

ANKK1 NRG1 PCLO TH NGF BICC1

2.87e-032541626C0011570
DiseaseInherited oocyte maturation defect

FBXO43 WEE2

3.42e-03161622cv:CN238505
Diseaselower body strength measurement

PCNX2 KIAA1671

3.42e-03161622EFO_0007999
Diseaseblood urea nitrogen measurement

NRG1 DCDC2 SHROOM3 DCDC1 SCAF8 TANC1 LRBA BICC1

3.63e-034521628EFO_0004741
Diseaseplasma beta-amyloid 1-40 measurement

RFC3 PDS5A

3.86e-03171622EFO_0005659
Diseasediabetic neuropathy (biomarker_via_orthology)

NRG1 NGF

3.86e-03171622DOID:9743 (biomarker_via_orthology)
Diseasecopine-1 measurement

DLGAP4 NFS1

3.86e-03171622EFO_0008102
Diseaseurate measurement

NRG1 NR2E3 DCDC1 FAAP20 TEX14 CEP89 ZNF827 PIP5KL1 NINL ANXA9 BICC1 CNTN2

4.00e-0389516212EFO_0004531
DiseaseAbnormality of refraction

ANK3 TDRD9 PCLO PHRF1 MFSD2A ZNF516 COBL PEAK1 PCDH9 BICC1

4.17e-0367316210HP_0000539
Diseaseretinal layer thickness measurement

TDRD9 COBL INVS

4.42e-03601623EFO_0600002
Diseaseosteochondrodysplasia (is_implicated_in)

MATN3 TRPS1

4.82e-03191622DOID:2256 (is_implicated_in)
Diseasecytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant

PCLO CDH23

4.82e-03191622EFO_0007044, EFO_0020106
Diseaseserum IgE measurement

SCAF8 TLN1 SIPA1L2

5.30e-03641623EFO_0004579
DiseaseDepressive disorder

ANKK1 NRG1 PCLO TH NGF BICC1

5.37e-032891626C0011581

Protein segments in the cluster

PeptideGeneStartEntry
NSRAEGQTLVQPSVA

PKP4

191

Q99569
AEPTVDQRLGQQRAE

CACNA1A

841

O00555
EPRIQVTDQQDGVRA

BTNL10

151

A8MVZ5
QGAELDAQQRNLRTP

ANKK1

516

Q8NFD2
RSTEPQREAEQEGGQ

B3GALT4

201

O96024
QARADVNGEREAPLT

ARHGEF15

176

O94989
RANRTEENVSDGSPN

CDKN1B

166

P46527
PGSERAAERAAAAQQ

BICC1

696

Q9H694
RQEAANESNTRVPRV

CCDC140

26

Q96MF4
PGDVASNRRENSVQV

CDH23

2481

Q9H251
ATQQSLGEQSNPRRS

DLGAP4

401

Q9Y2H0
GSAQPQVVANSQRET

ARMCX4

906

Q5H9R4
QVVANSQRETLPGAR

ARMCX4

911

Q5H9R4
QGSAVEPEQNRVNRE

ATP8B1

36

O43520
INRVAEPAQREQSTG

CPNE6

416

O95741
GETNPRSIQNNVREA

ITIH4

391

Q14624
SRQREELVAAAGAPQ

NWD1

1526

Q149M9
AESAEIPNTAGRTQR

NBPF4

621

Q96M43
DAVQNERQPRSTAQV

NR2E3

116

Q9Y5X4
NSELNPSTGNRSREQ

PDS5A

1171

Q29RF7
ERERQQPGEAATPQA

RILP

176

Q96NA2
ETPAQFRQRSQAEDV

KAT2A

271

Q92830
RTNPAGRFSTQEEIQ

NRG1

611

Q02297
LSETVNRDGPRQDTQ

NUP205

1786

Q92621
QSPEGQAQARIRNLE

PALM3

71

A6NDB9
NQGAPAESREVLQDT

PCDH12

831

Q9NPG4
RERENIPRGSVQFAQ

KIAA1107

846

Q9UPP5
GAREEPTVQQAQRRS

L3MBTL3

656

Q96JM7
NGALVDARAREEQTP

ANK2

486

Q01484
TQPAVRTQNGVSERE

DAB2

371

P98082
NPASSRTGNEAEVRI

DCC

216

P43146
IRRQQGPQATDIVVS

DCDC1

1756

M0R2J8
EEVAAPQRAARGQVA

KLHL34

296

Q8N239
RSVQGAQSPEESRAQ

PIP5KL1

306

Q5T9C9
RTNRETAGPSANVIQ

KMT2C

2881

Q8NEZ4
DGRPQDQVNEVAARA

MATN3

196

O15232
TDGRPQDRVAEVAAQ

MATN4

146

O95460
NVEENSSGDQRRAPL

MAGED1

256

Q9Y5V3
RVETQEVNPGASRDQ

KIAA1671

996

Q9BY89
ARQQVASLIGADPRE

NFS1

106

Q9Y697
ARVAGQTRNITVDPR

NGF

61

P01138
RVEQQPSVEGAAALR

FAAP20

131

Q6NZ36
SQDNSPPEDRNQRVV

HSFX4

56

A0A1B0GTS1
RGVVEETSNNAEPGR

KIAA1109

1771

Q2LD37
SQQERRVSTDLPEGQ

HERC1

1421

Q15751
RREEGQLQQPSTSAS

HERC1

1466

Q15751
QGDPERNQLQVESRS

KCNH5

726

Q8NCM2
PTTQGEARREEATRQ

CPSF1

826

Q10570
QSRGRIPIVAQNSEE

PCLO

4346

Q9Y6V0
QRRQGLAETASPVAV

PCM1

851

Q15154
SNTRLAVQIERDPGN

PCNX2

1366

A6NKB5
QGRQQRVPAVRFNSS

PLXNA3

726

P51805
EVRDNRTPQRVAQGL

FAT2

2041

Q9NYQ8
QPVIELSVSENNRRG

PCDH9

471

Q9HC56
TAPQIRGNETNSRET

PEAK1

161

Q9H792
QAARPQETQEGLQRE

MYOC

106

Q99972
GRVQEAARPEEVVSQ

PHRF1

1376

Q9P1Y6
ALVAEPVQNGSRSRQ

RASAL2

906

Q9UJF2
IRRDINVSVGSQQPD

LRBA

961

P50851
VERTQQVARGEPGSA

MIR1-1HG

21

Q9H1L0
QDVQALQRAEGPSRE

ANXA9

201

O76027
DNAPEERARGITINA

TUFM

96

P49411
NRVGPNGESRAQTVT

RIC3

166

Q7Z5B4
IEQPVLVQGNSNRRS

MON2

191

Q7Z3U7
AIVNPGRDSATNQIR

PTPRZ1

441

P23471
RASEIQPLQGTNENR

MFSD6

716

Q6ZSS7
SQDNSPPEDRNQRVV

HSFX3

56

A0A1B0GWH4
AAARAQEPLQDQGQR

IQSEC3

86

Q9UPP2
QPQTREQDRAHQTGE

CRNN

211

Q9UBG3
QEGVREEQRSPFNDR

PCF11

696

O94913
GVREQREPYEAQQSE

MFSD2A

276

Q8NA29
SVQAQARIPGSQREQ

FBXO43

581

Q4G163
QLEGVNTPRQRAVEA

EXOC5

116

O00471
RPGRTNVQQTTDLEI

HECTD1

1781

Q9ULT8
QIDEQLRQIGASSRP

FMR1

436

Q06787
SIPTQERNRVFASGQ

IL1RL1

56

Q01638
RQEQPAAVGQSGVRR

BOC

1021

Q9BWV1
LQDTLTRTGVQDNPR

CEP89

736

Q96ST8
SQEQRARDTEGPRQG

CCDC188

81

H7C350
QTRLQPLQEGDSRQD

FSTL4

156

Q6MZW2
DGERTQATERVNSQP

COBL

656

O75128
EIREARQQAAASQSP

ANK3

1996

Q12955
RAEEAGARVQQNVPS

APOL1

26

O14791
NSSDDVQERRAQGSP

CERKL

396

Q49MI3
VRTNPANIEGNAETA

CNTN2

656

Q02246
LENSREIIPRQGSNT

LYST

221

Q99698
SRVLANPGNSQVARV

KPNB1

41

Q14974
ADESQEPQSQVRAQR

MAN1C1

161

Q9NR34
RSTRIPGTDAQAQAE

MIDEAS

571

Q6PJG2
RQQSAPQVAVNGHRD

EPS8L1

451

Q8TE68
RESTVDGNVQRESRP

ERICH5

46

Q6P6B1
NQRAEAPADQRSQGT

CCDC8

366

Q9H0W5
RERAPAVQGADNQRA

CCDC8

416

Q9H0W5
TRAAVATQEQGNAPA

DNAH2

26

Q9P225
QGIQNSVTDRPETRE

RSC1A1

526

Q92681
QVIEDDRNNRGTEPF

SEC24C

331

P53992
RVENSIPAAGETQNV

SART3

646

Q15020
QRPNVSSNSEILGVR

SCAF8

816

Q9UPN6
NSVQRQSTGERDGRP

INPP5F

186

Q9Y2H2
AAQGAQRERLPVTDD

PRRT3

101

Q5FWE3
EQQARPARVNGGTDE

DCDC2

396

Q9UHG0
DVNRRDQQRNPGTST

IGFBP6

131

P24592
DSGVEEPRNASLQAQ

IL17RC

181

Q8NAC3
PARRQQETLDVGSFQ

FAM166A

186

Q6J272
NPSDAGNSDRVVIQE

RFC3

96

P40938
VSSDLQGTNSRRPNE

INVS

676

Q9Y283
QDPRRQVTLTQAGDV

OTOG

576

Q6ZRI0
SLEPRRVTNQGAVDS

MN1

216

Q10571
VNGTASEQDQDPQRV

MCAM

466

P43121
RSPGAEEVQSQEQTR

SYTL5

146

Q8TDW5
RARQNLSQVPEADSV

TRIM47

316

Q96LD4
DNGDRPAAVVERNTL

THADA

876

Q6YHU6
SDPEQIGSNVTRQRS

REPS1

521

Q96D71
QGRPRESTAQAKATQ

TEX14

866

Q8IWB6
GRQQQQRAESTATRP

SLC47A2

506

Q86VL8
QRGSRAPESRVVAQV

SPATA5L1

311

Q9BVQ7
QAAQPLQGEAREAAR

TMEM191B

106

P0C7N4
QAAQPLQGEAREAAR

TMEM191C

106

A6NGB0
AAREEVQRQDVAPGA

TDRD9

36

Q8NDG6
NLSPVQSTGEREAQR

LINC00869

66

P0C866
EVSTNVRQGRRQSEP

PLEKHG3

436

A1L390
RRTQSSGQDGRPQEE

PIP5K1C

551

O60331
AVQDRLNEQEGVPSV

FAF2

46

Q96CS3
AQAQARAEAEAGSPR

EPPK1

2496

P58107
TNAGVSVLEVPRENQ

SIPA1L2

451

Q9P2F8
TNNPDREVQAETQGR

SIGLEC8

81

Q9NYZ4
SKFEQREQGSQRPSV

SHROOM3

786

Q8TF72
SNANQTVPDRSDRSG

RNF146

316

Q9NTX7
GSISAENQRPREDAV

TANC1

481

Q9C0D5
EQRLVREANNGSSPA

STAT5B

116

P51692
GSLSQPDVARREQNT

STARD9

3696

Q9P2P6
VPVRAEAQVELRGNS

ITGA2B

771

P08514
GPRRRQAQDTEATQS

NINL

876

Q9Y2I6
VATNNPARAVQEETR

SIGLEC12

76

Q96PQ1
PDNVAEVVAGARRLQ

KBTBD11

201

O94819
GQAQETAVAQRKPRA

AHNAK2

426

Q8IVF2
NERAVTPNGEIRASE

ARAP1

786

Q96P48
RAQRNPGEEQSRRND

CIR1

406

Q86X95
VNAARRRVIPQQSGA

CLCA1

681

A8K7I4
SRVPGAEDNARNETL

TNFRSF10D

266

Q9UBN6
QHAQRNVGERSPDQS

TNIP2

176

Q8NFZ5
ERREEAQRAQQAVPG

TSPY9

91

A0A494C1R9
NEEQVNGSPLERRSE

TRPS1

971

Q9UHF7
TQAGRRVAELDPVNS

ZNF516

401

Q92618
RQSALEEAQQNPREG

SMOC1

231

Q9H4F8
ERREEAQRAQQAVPG

TSPY4

91

P0CV99
EVPREAGDGQRQQAT

ZNF497

46

Q6ZNH5
ERSPNGVQLERSNTA

ZNF846

96

Q147U1
VDDGPIQNTLRQARV

TMPRSS11F

336

Q6ZWK6
VRRRSVQQEPQNGGA

SBSPON

96

Q8IVN8
ERNPTAQQLRDVEGQ

RP1L1

121

Q8IWN7
QAATELVQASRGTPQ

TLN1

1251

Q9Y490
QERRENVSSPQARTA

TIE1

591

P35590
VTPERNRTNQGNQDL

SCEL

436

O95171
NEPSARRSSGENVEN

RLIM

156

Q9NVW2
DIGQATNNRSNLVRP

ZDBF2

166

Q9HCK1
AETSQRLVGISQPRN

TROAP

76

Q12815
SGRGTQVFVTEQNPR

SIRPD

131

Q9H106
EVQSSRNNEIGNPVS

USF3

1751

Q68DE3
SSQRPGAEDNVLNEI

TNFRSF10B

261

O14763
SGLRAQSVAQPEDQV

TRAV3

16

A0A0B4J244
NSDNLRPVVIDGSNV

ZC3H12B

186

Q5HYM0
AQSGEPRRLTQAQVA

ZNF839

591

A8K0R7
AAATANGRVESPVNV

ZNF827

136

Q17R98
PELRRQRSGEVENNS

TNFRSF13B

116

O14836
NQRREGKDVNSSSPV

TSNAX

21

Q99598
GFADVSQQIRVRNRP

nan

11

Q6ZR54
TRGENQSVRAAVRSP

LINC01356

126

Q8N9X3
SPRGALEDQQQRAIS

SLC46A2

61

Q9BY10
ERELDEPRQQVSQGT

ZBED9

131

Q6R2W3
QASQRPAVVQTQADG

SNAPC4

761

Q5SXM2
ERELREAQQAQSPQG

WEE2

511

P0C1S8
RIQDAGPASRDVQAT

ZC3HAV1

461

Q7Z2W4
QVRTTGARDRVTNQP

POLR1B

1011

Q9H9Y6
LQVSQVPAGERQTDR

XIRP1

646

Q702N8
EEINRVVRNAGPIAN

SLFN5

706

Q08AF3
QAALQGEATPRAAQE

THAP4

146

Q8WY91
VNLVERNRIGSENPS

USP13

456

Q92995
NQPSSEAAGRSEREQ

THEG

11

Q9P2T0
IQARVREQQPESGEE

ZNF500

106

O60304
VPDAQAATRRQAVGL

CX3CL1

331

P78423
DSPQAVRRSLEGVQD

TH

501

P07101
AAVTARPGQEIRQRT

LNPK

156

Q9C0E8
QEIRNPNGTVTVISR

NECTIN1

196

Q15223