Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.75e-13	28	44	7	GO:0005242
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	GABRB1 KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	3.23e-10	193	44	9	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	GABRB1 KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	3.88e-10	197	44	9	GO:0022834
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	6.84e-10	140	44	8	GO:0099094
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.32e-09	152	44	8	GO:0022843
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.42e-09	102	44	7	GO:0005249
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNN2 KCNN3 KCNJ18 SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.78e-09	167	44	8	GO:0015079
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	5.47e-09	182	44	8	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	5.96e-09	184	44	8	GO:0022832
GeneOntologyMolecularFunction	potassium channel activity	KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.19e-08	128	44	7	GO:0005267
GeneOntologyMolecularFunction	gated channel activity	GABRB1 KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	3.90e-08	334	44	9	GO:0022836
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	KCNN2 KCNN3 KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	5.20e-08	465	44	10	GO:0046873
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 SLC45A3 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	5.66e-08	758	44	12	GO:0015318
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	KCNN2 KCNN3 KCNJ18 SLC12A2 SLC45A3 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	8.01e-08	627	44	11	GO:0022890
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 SLC45A3 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	9.26e-08	793	44	12	GO:0015075
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 SLC45A3 ATP2B1 SVOPL KCNJ4 SLC2A7 KCNJ5 RYR1 KCNJ9 KCNJ12	1.27e-07	1180	44	14	GO:0022857
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	KCNN2 KCNN3 KCNJ18 SLC12A2 SLC45A3 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.43e-07	664	44	11	GO:0008324
GeneOntologyMolecularFunction	channel activity	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.61e-07	525	44	10	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.64e-07	526	44	10	GO:0022803
GeneOntologyMolecularFunction	transporter activity	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 SLC45A3 ATP2B1 SVOPL KCNJ4 SLC2A7 KCNJ5 RYR1 KCNJ9 KCNJ12	3.74e-07	1289	44	14	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRB1 KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	5.75e-07	459	44	9	GO:0005216
GeneOntologyMolecularFunction	monoatomic cation channel activity	KCNN2 KCNN3 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	7.22e-07	343	44	8	GO:0005261
GeneOntologyMolecularFunction	glucosamine-6-phosphate deaminase activity	GNPDA1 GNPDA2	4.75e-06	2	44	2	GO:0004342
GeneOntologyMolecularFunction	PDZ domain binding	KCNJ18 ATP2B1 KCNJ4 KCNJ9 KCNJ12	7.32e-06	123	44	5	GO:0030165
GeneOntologyMolecularFunction	G-protein activated inward rectifier potassium channel activity	KCNJ5 KCNJ9	2.84e-05	4	44	2	GO:0015467
GeneOntologyMolecularFunction	small conductance calcium-activated potassium channel activity	KCNN2 KCNN3	2.84e-05	4	44	2	GO:0016286
GeneOntologyMolecularFunction	calcium-activated potassium channel activity	KCNN2 KCNN3	4.25e-04	14	44	2	GO:0015269
GeneOntologyMolecularFunction	protein domain specific binding	RUFY2 SIGLEC16 KCNN2 KCNJ18 ATP2B1 KCNJ4 KCNJ9 KCNJ12	5.73e-04	875	44	8	GO:0019904
GeneOntologyMolecularFunction	calcium-activated cation channel activity	KCNN2 KCNN3	1.61e-03	27	44	2	GO:0005227
GeneOntologyMolecularFunction	calmodulin binding	KCNN2 KCNN3 ATP2B1 RYR1	1.62e-03	230	44	4	GO:0005516
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC45A3 SLC2A7	1.86e-03	29	44	2	GO:0051119
GeneOntologyMolecularFunction	monoatomic ion-gated channel activity	KCNN2 KCNN3	2.12e-03	31	44	2	GO:0022839
GeneOntologyMolecularFunction	deaminase activity	GNPDA1 GNPDA2	2.55e-03	34	44	2	GO:0019239
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC45A3 SLC2A7	3.86e-03	42	44	2	GO:0015144
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	CAD GNPDA1 GNPDA2	4.07e-03	146	44	3	GO:0016810
GeneOntologyBiologicalProcess	potassium ion import across plasma membrane	KCNJ18 SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.11e-09	51	44	6	GO:1990573
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	KCNN2 KCNN3 KCNJ18 SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.84e-08	232	44	8	GO:0071805
GeneOntologyBiologicalProcess	potassium ion transport	KCNN2 KCNN3 KCNJ18 SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	9.70e-08	272	44	8	GO:0006813
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	KCNJ18 SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	5.45e-07	142	44	6	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	KCNJ18 SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	5.45e-07	142	44	6	GO:0098659
GeneOntologyBiologicalProcess	glucosamine catabolic process	GNPDA1 GNPDA2	4.45e-06	2	44	2	GO:0006043
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	6.79e-06	1017	44	11	GO:0098660
GeneOntologyBiologicalProcess	import across plasma membrane	KCNJ18 SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	8.92e-06	230	44	6	GO:0098739
GeneOntologyBiologicalProcess	N-acetylglucosamine catabolic process	GNPDA1 GNPDA2	1.33e-05	3	44	2	GO:0006046
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.62e-05	1115	44	11	GO:0034220
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	KCNN2 KCNN3 KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.88e-05	922	44	10	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	KCNN2 KCNN3 KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	2.26e-05	942	44	10	GO:0098655
GeneOntologyBiologicalProcess	metal ion transport	KCNN2 KCNN3 KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	3.77e-05	1000	44	10	GO:0030001
GeneOntologyBiologicalProcess	glucosamine metabolic process	GNPDA1 GNPDA2	6.64e-05	6	44	2	GO:0006041
GeneOntologyBiologicalProcess	membrane repolarization during atrial cardiac muscle cell action potential	KCNN2 KCNJ5	9.28e-05	7	44	2	GO:0098914
GeneOntologyBiologicalProcess	N-acetylneuraminate catabolic process	GNPDA1 GNPDA2	9.28e-05	7	44	2	GO:0019262
GeneOntologyBiologicalProcess	monoatomic ion transport	GABRB1 KCNN2 KCNN3 KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.09e-04	1374	44	11	GO:0006811
GeneOntologyBiologicalProcess	monoatomic cation transport	KCNN2 KCNN3 KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.28e-04	1157	44	10	GO:0006812
GeneOntologyBiologicalProcess	glucosamine-containing compound catabolic process	GNPDA1 GNPDA2	1.59e-04	9	44	2	GO:1901072
GeneOntologyBiologicalProcess	UDP-N-acetylglucosamine biosynthetic process	GNPDA1 GNPDA2	1.59e-04	9	44	2	GO:0006048
GeneOntologyBiologicalProcess	regulation of monoatomic ion transport	KCNN2 KCNJ18 ATP2B1 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.02e-04	577	44	7	GO:0043269
GeneOntologyBiologicalProcess	regulation of transmembrane transport	KCNN2 KCNJ18 HK2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.29e-04	589	44	7	GO:0034762
GeneOntologyBiologicalProcess	atrial cardiac muscle cell membrane repolarization	KCNN2 KCNJ5	2.42e-04	11	44	2	GO:0099624
GeneOntologyBiologicalProcess	amino sugar biosynthetic process	GNPDA1 GNPDA2	2.42e-04	11	44	2	GO:0046349
GeneOntologyBiologicalProcess	regulation of monoatomic ion transmembrane transport	KCNN2 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.43e-04	417	44	6	GO:0034765
GeneOntologyBiologicalProcess	N-acetylneuraminate metabolic process	GNPDA1 GNPDA2	3.42e-04	13	44	2	GO:0006054
GeneOntologyBiologicalProcess	UDP-N-acetylglucosamine metabolic process	GNPDA1 GNPDA2	3.98e-04	14	44	2	GO:0006047
GeneOntologyBiologicalProcess	amino sugar catabolic process	GNPDA1 GNPDA2	4.59e-04	15	44	2	GO:0046348
GeneOntologyBiologicalProcess	fructose 6-phosphate metabolic process	GNPDA1 HK2	5.24e-04	16	44	2	GO:0006002
GeneOntologyBiologicalProcess	atrial cardiac muscle cell to AV node cell communication	KCNN2 KCNJ5	7.43e-04	19	44	2	GO:0086066
GeneOntologyBiologicalProcess	atrial cardiac muscle cell to AV node cell signaling	KCNN2 KCNJ5	7.43e-04	19	44	2	GO:0086026
GeneOntologyBiologicalProcess	atrial cardiac muscle cell action potential	KCNN2 KCNJ5	7.43e-04	19	44	2	GO:0086014
GeneOntologyBiologicalProcess	N-acetylglucosamine metabolic process	GNPDA1 GNPDA2	8.25e-04	20	44	2	GO:0006044
GeneOntologyBiologicalProcess	response to caffeine	CAD RYR1	9.10e-04	21	44	2	GO:0031000
GeneOntologyBiologicalProcess	nucleotide-sugar biosynthetic process	GNPDA1 GNPDA2	1.09e-03	23	44	2	GO:0009226
GeneOntologyBiologicalProcess	cardiac conduction	KCNN2 ATP2B1 KCNJ5	1.27e-03	100	44	3	GO:0061337
GeneOntologyBiologicalProcess	membrane repolarization during cardiac muscle cell action potential	KCNN2 KCNJ5	1.51e-03	27	44	2	GO:0086013
GeneOntologyBiologicalProcess	muscle contraction	KCNN2 ATP2B1 KCNJ5 RYR1 KCNJ12	1.56e-03	400	44	5	GO:0006936
GeneOntologyBiologicalProcess	glucosamine-containing compound metabolic process	GNPDA1 GNPDA2	1.74e-03	29	44	2	GO:1901071
GeneOntologyBiologicalProcess	import into cell	RUFY2 KCNJ18 SLC12A2 KCNJ4 KCNJ5 KCNJ9 RABGAP1L KCNJ12	1.75e-03	1074	44	8	GO:0098657
GeneOntologyCellularComponent	T-tubule	KCNN2 KCNJ18 KCNJ5 RYR1 KCNJ12	6.56e-07	79	44	5	GO:0030315
GeneOntologyCellularComponent	monoatomic ion channel complex	GABRB1 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.29e-05	378	44	7	GO:0034702
GeneOntologyCellularComponent	somatodendritic compartment	GABRB1 ZDHHC5 KCNN2 KCNN3 CAD KCNJ18 SLC12A2 ATP2B1 KCNJ4 ARHGAP44 KCNJ12	3.50e-05	1228	44	11	GO:0036477
GeneOntologyCellularComponent	sarcolemma	KCNN2 KCNJ18 KCNJ5 RYR1 KCNJ12	4.79e-05	190	44	5	GO:0042383
GeneOntologyCellularComponent	transmembrane transporter complex	GABRB1 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.01e-04	523	44	7	GO:1902495
GeneOntologyCellularComponent	transporter complex	GABRB1 KCNJ18 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.38e-04	550	44	7	GO:1990351
GeneOntologyCellularComponent	neuronal cell body	KCNN2 KCNN3 CAD KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ12	3.10e-04	835	44	8	GO:0043025
GeneOntologyCellularComponent	dendrite	GABRB1 ZDHHC5 KCNN2 KCNJ18 ATP2B1 KCNJ4 ARHGAP44 KCNJ12	3.71e-04	858	44	8	GO:0030425
GeneOntologyCellularComponent	dendritic tree	GABRB1 ZDHHC5 KCNN2 KCNJ18 ATP2B1 KCNJ4 ARHGAP44 KCNJ12	3.77e-04	860	44	8	GO:0097447
GeneOntologyCellularComponent	cell body	KCNN2 KCNN3 CAD KCNJ18 SLC12A2 ATP2B1 KCNJ4 KCNJ12	6.30e-04	929	44	8	GO:0044297
Domain	K_chnl_inward-rec_Kir_cyto	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.18e-10	16	43	5	IPR013518
Domain	IRK	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.18e-10	16	43	5	PF01007
Domain	-	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.18e-10	16	43	5	2.60.40.1400
Domain	K_chnl_inward-rec_Kir	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.18e-10	16	43	5	IPR016449
Domain	Ig_E-set	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	3.95e-06	104	43	5	IPR014756
Domain	Glucosamine6P_isomerase_CS	GNPDA1 GNPDA2	5.18e-06	2	43	2	IPR018321
Domain	K_chnl_inward-rec_Kir2.2	KCNJ18 KCNJ12	5.18e-06	2	43	2	IPR003272
Domain	Glucosamine6P_isomerase	GNPDA1 GNPDA2	5.18e-06	2	43	2	IPR004547
Domain	GLC_GALNAC_ISOMERASE	GNPDA1 GNPDA2	5.18e-06	2	43	2	PS01161
Domain	K_chnl_inward-rec_Kir_N	KCNJ18 KCNJ12	1.55e-05	3	43	2	IPR013673
Domain	IRK_N	KCNJ18 KCNJ12	1.55e-05	3	43	2	PF08466
Domain	CaM-bd_dom	KCNN2 KCNN3	3.10e-05	4	43	2	IPR004178
Domain	CaMBD	KCNN2 KCNN3	3.10e-05	4	43	2	SM01053
Domain	SK_channel	KCNN2 KCNN3	3.10e-05	4	43	2	PF03530
Domain	CaMBD	KCNN2 KCNN3	3.10e-05	4	43	2	PF02888
Domain	K_chnl_Ca-activ_SK	KCNN2 KCNN3	3.10e-05	4	43	2	IPR015449
Domain	Glc/Gal-6P_isomerase	GNPDA1 GNPDA2	3.10e-05	4	43	2	IPR006148
Domain	Glucosamine_iso	GNPDA1 GNPDA2	3.10e-05	4	43	2	PF01182
Domain	K_chnl_dom	KCNN2 KCNN3	1.06e-03	21	43	2	IPR013099
Domain	Ion_trans_2	KCNN2 KCNN3	1.06e-03	21	43	2	PF07885
Domain	Sugar_tr	SVOPL SLC2A7	3.10e-03	36	43	2	PF00083
Domain	MFS_sugar_transport-like	SVOPL SLC2A7	3.10e-03	36	43	2	IPR005828
Domain	MFS_dom	SLC45A3 SVOPL SLC2A7	3.61e-03	134	43	3	IPR020846
Domain	ARM-type_fold	ARFGEF1 KIFAP3 SMG1 NUP188	7.54e-03	339	43	4	IPR016024
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GABRB1 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	4.66e-09	60	33	6	MM15708
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	7.00e-09	30	33	5	MM14542
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.83e-08	36	33	5	MM14544
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	5.21e-08	44	33	5	MM15709
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNN3 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	9.20e-08	98	33	6	MM14545
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNN2 KCNN3 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.24e-07	103	33	6	M1073
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GABRB1 KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.55e-07	60	33	5	M976
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	GABRB1 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	9.03e-07	144	33	6	MM14501
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.24e-06	35	33	4	M1075
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.88e-06	43	33	4	M954
Pathway	REACTOME_CARDIAC_CONDUCTION	KCNJ18 ATP2B1 KCNJ4 RYR1 KCNJ12	3.81e-06	103	33	5	MM15196
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	GABRB1 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	8.28e-06	211	33	6	MM14502
Pathway	REACTOME_NEURONAL_SYSTEM	GABRB1 KCNN3 KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.01e-05	335	33	7	MM14503
Pathway	REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL	KCNJ18 KCNJ4 KCNJ12	1.10e-05	19	33	3	MM15194
Pathway	REACTOME_MUSCLE_CONTRACTION	KCNJ18 ATP2B1 KCNJ4 RYR1 KCNJ12	3.76e-05	165	33	5	MM15026
Pathway	REACTOME_NEURONAL_SYSTEM	GABRB1 KCNN2 KCNN3 KCNJ4 KCNJ5 KCNJ9 KCNJ12	3.77e-05	411	33	7	M735
Pathway	REACTOME_GLUCOSE_METABOLISM	NUP188 GNPDA1 HK2 GNPDA2	3.83e-05	82	33	4	MM15394
Pathway	REACTOME_GLUCOSE_METABOLISM	NUP188 GNPDA1 HK2 GNPDA2	4.41e-05	85	33	4	M1870
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	GABRB1 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.06e-04	205	33	5	M752
Pathway	KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM	GNPDA1 HK2 GNPDA2	1.45e-04	44	33	3	M8104
Pathway	REACTOME_CA2_ACTIVATED_K_CHANNELS	KCNN2 KCNN3	1.89e-04	9	33	2	M26932
Pathway	REACTOME_CARDIAC_CONDUCTION	ATP2B1 KCNJ4 RYR1 KCNJ12	2.30e-04	130	33	4	M27454
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	GABRB1 KCNJ4 KCNJ5 KCNJ9 KCNJ12	3.80e-04	270	33	5	M15514
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC45A3 SLC2A7	8.86e-04	19	33	2	MM14718
Pathway	REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL	KCNJ4 KCNJ12	8.86e-04	19	33	2	M27452
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC45A3 SLC2A7	1.09e-03	21	33	2	M27058
Pathway	REACTOME_MUSCLE_CONTRACTION	ATP2B1 KCNJ4 RYR1 KCNJ12	1.23e-03	203	33	4	M5485
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	NUP188 GNPDA1 HK2 GNPDA2	3.52e-03	271	33	4	MM15406
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	NUP188 GNPDA1 HK2 GNPDA2	4.38e-03	288	33	4	M16864
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	ATP2B1 KCNJ5 RYR1	4.82e-03	147	33	3	MM15854
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	ATP2B1 KCNJ5 RYR1	5.19e-03	151	33	3	M39329
Pubmed	The inward rectifier potassium channel family.	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.73e-14	6	45	5	7580148
Pubmed	Rare independent mutations in renal salt handling genes contribute to blood pressure variation.	SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	7.47e-11	22	45	5	18391953
Pubmed	Molecular cloning and functional expression of cDNA encoding a second class of inward rectifier potassium channels in the mouse brain.	KCNJ18 KCNJ4 KCNJ12	2.02e-09	3	45	3	8083233
Pubmed	International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels.	KCNJ4 KCNJ5 KCNJ9 KCNJ12	3.30e-09	15	45	4	16382105
Pubmed	Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.	KCNJ18 KCNJ4 KCNJ12	8.09e-09	4	45	3	20798526
Pubmed	Dendritic excitability of mouse frontal cortex pyramidal neurons is shaped by the interaction among HCN, Kir2, and Kleak channels.	KCNJ18 KCNJ4 KCNJ12	2.02e-08	5	45	3	16177047
Pubmed	Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain.	KCNJ4 KCNJ5 KCNJ9	2.02e-08	5	45	3	7926018
Pubmed	Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.	KCNJ4 KCNJ5 KCNJ9 KCNJ12	3.03e-08	25	45	4	17185339
Pubmed	A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.	KCNJ18 KCNJ4 KCNJ12	2.41e-07	10	45	3	14960569
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	GABRB1 RAB23 KIFAP3 SLC12A2 ATP2B1 KCNJ4 KCNJ9	8.55e-07	405	45	7	38187761
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNN2 KCNN3 KCNJ4 KCNJ5 KCNJ9	1.02e-06	139	45	5	16985003
Pubmed	PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis.	KCNJ18 KCNJ4 KCNJ12	1.63e-06	18	45	3	21511879
Pubmed	Nuclear localization and dominant-negative suppression by a mutant SKCa3 N-terminal channel fragment identified in a patient with schizophrenia.	KCNN2 KCNN3	1.64e-06	2	45	2	11395478
Pubmed	A novel isoform of SK2 assembles with other SK subunits in mouse brain.	KCNN2 KCNN3	1.64e-06	2	45	2	15797870
Pubmed	Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.	GNPDA1 GNPDA2	1.64e-06	2	45	2	12965206
Pubmed	Distribution of Ca2+-activated K channels, SK2 and SK3, in the normal and Hirschsprung's disease bowel.	KCNN2 KCNN3	1.64e-06	2	45	2	12778407
Pubmed	Role of SK channel activation in determining the action potential configuration in freshly isolated human atrial myocytes from the SKArF study.	KCNN2 KCNN3	1.64e-06	2	45	2	30922569
Pubmed	Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse.	KCNJ18 KCNJ12	1.64e-06	2	45	2	15705530
Pubmed	Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.	GNPDA1 GNPDA2	1.64e-06	2	45	2	12616532
Pubmed	Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels.	KCNN2 KCNN3	1.64e-06	2	45	2	27874831
Pubmed	Ethanol opens G-protein-activated inwardly rectifying K+ channels.	KCNJ4 KCNJ5	1.64e-06	2	45	2	10570486
Pubmed	SK2 and SK3 expression differentially affect firing frequency and precision in dopamine neurons.	KCNN2 KCNN3	1.64e-06	2	45	2	22554781
Pubmed	Expression of postsynaptic Ca2+-activated K+ (SK) channels at C-bouton synapses in mammalian lumbar -motoneurons.	KCNN2 KCNN3	1.64e-06	2	45	2	23129791
Pubmed	Down-regulation of the small conductance calcium-activated potassium channels in diabetic mouse atria.	KCNN2 KCNN3	1.64e-06	2	45	2	25605734
Pubmed	Respiration and parturition affected by conditional overexpression of the Ca2+-activated K+ channel subunit, SK3.	KCNN2 KCNN3	1.64e-06	2	45	2	10988076
Pubmed	Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function.	KCNN2 KCNN3	1.64e-06	2	45	2	36502918
Pubmed	Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1.	KCNJ4 KCNJ12	4.91e-06	3	45	2	16258766
Pubmed	Comparative immunohistochemical distribution of three small-conductance Ca2+-activated potassium channel subunits, SK1, SK2, and SK3 in mouse brain.	KCNN2 KCNN3	4.91e-06	3	45	2	15234350
Pubmed	Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels.	KCNN2 KCNN3	4.91e-06	3	45	2	20689065
Pubmed	Molecular properties of small-conductance Ca2+-activated K+ channels expressed in murine colonic smooth muscle.	KCNN2 KCNN3	4.91e-06	3	45	2	11557517
Pubmed	Quantitative expression analysis of the small conductance calcium-activated potassium channels, SK1, SK2 and SK3, in human brain.	KCNN2 KCNN3	4.91e-06	3	45	2	11146124
Pubmed	The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.	KCNJ18 KCNJ12	4.91e-06	3	45	2	11410627
Pubmed	Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons.	KCNN2 KCNN3	4.91e-06	3	45	2	24434522
Pubmed	Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes.	KCNN2 KCNN3	4.91e-06	3	45	2	16055520
Pubmed	Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels.	KCNJ18 KCNJ12	4.91e-06	3	45	2	17640933
Pubmed	Small-conductance calcium-activated K(+) channels 3 (SK3) regulate blastocyst hatching by control of intracellular calcium concentration.	KCNN2 KCNN3	4.91e-06	3	45	2	22416006
Pubmed	HDAC2-dependent remodeling of KCa2.2 (KCNN2) and KCa2.3 (KCNN3) K+ channels in atrial fibrillation with concomitant heart failure.	KCNN2 KCNN3	4.91e-06	3	45	2	33310041
Pubmed	Differential polyamine sensitivity in inwardly rectifying Kir2 potassium channels.	KCNJ4 KCNJ12	4.91e-06	3	45	2	16373386
Pubmed	Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation.	KCNJ18 KCNJ12	4.91e-06	3	45	2	10904001
Pubmed	Identification of GIRK2-4 subunits in human esophageal smooth muscle cells.	KCNJ5 KCNJ9	4.91e-06	3	45	2	21637918
Pubmed	Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome.	KCNJ4 KCNJ12	4.91e-06	3	45	2	12032359
Pubmed	Partial apamin sensitivity of human small conductance Ca2+-activated K+ channels stably expressed in Chinese hamster ovary cells.	KCNN2 KCNN3	4.91e-06	3	45	2	12382077
Pubmed	Hyperalgesia and blunted morphine analgesia in G protein-gated potassium channel subunit knockout mice.	KCNJ5 KCNJ9	4.91e-06	3	45	2	12499858
Pubmed	Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currents.	KCNN2 KCNN3	4.91e-06	3	45	2	15190101
Pubmed	Assignment of the murine inward rectifier potassium channel Irk2 (Kir2.2) gene to the central region of mouse chromosome 11.	KCNJ18 KCNJ12	9.81e-06	4	45	2	8921409
Pubmed	Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2.	KCNJ4 KCNJ12	9.81e-06	4	45	2	15958527
Pubmed	Structural characterization of the mouse Girk genes.	KCNJ5 KCNJ9	9.81e-06	4	45	2	11891065
Pubmed	Different conformational switches underlie the calmodulin-dependent modulation of calcium pumps and channels.	ATP2B1 RYR1	9.81e-06	4	45	2	18201104
Pubmed	Co-expression of human Kir3 subunits can yield channels with different functional properties.	KCNJ5 KCNJ9	9.81e-06	4	45	2	10659995
Pubmed	Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum.	KCNJ5 KCNJ9	9.81e-06	4	45	2	18088366
Pubmed	Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses.	KCNN2 KCNN3	9.81e-06	4	45	2	12882916
Pubmed	Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels.	KCNJ5 KCNJ9	9.81e-06	4	45	2	7499385
Pubmed	Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines.	KCNJ5 KCNJ9	9.81e-06	4	45	2	16109170
Pubmed	Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells.	KCNJ5 KCNJ9	9.81e-06	4	45	2	8630252
Pubmed	Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) Increases Small-Conductance Ca2+-Activated K+ Current in Patients with Chronic Atrial Fibrillation.	KCNN2 KCNN3	9.81e-06	4	45	2	29737974
Pubmed	A Soluble Epoxide Hydrolase Inhibitor Upregulated KCNJ12 and KCNIP2 by Downregulating MicroRNA-29 in a Mouse Model of Myocardial Infarction.	KCNJ18 KCNJ12	9.81e-06	4	45	2	32990585
Pubmed	Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.	GNPDA1 GNPDA2	1.63e-05	5	45	2	26887390
Pubmed	Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells.	KCNJ5 KCNJ9	1.63e-05	5	45	2	19558451
Pubmed	Inward Rectifier Potassium Channels (Kir2.x) and Caveolin-3 Domain-Specific Interaction: Implications for Purkinje Cell-Dependent Ventricular Arrhythmias.	KCNJ4 KCNJ12	1.63e-05	5	45	2	29326130
Pubmed	Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97.	KCNJ4 KCNJ12	1.63e-05	5	45	2	11181181
Pubmed	Proteome-wide analysis of phospho-regulated PDZ domain interactions.	ATP2B1 KCNJ4 KCNJ12	2.24e-05	42	45	3	30126976
Pubmed	Complex trait analysis of the hippocampus: mapping and biometric analysis of two novel gene loci with specific effects on hippocampal structure in mice.	GABRB1 KCNJ9	2.45e-05	6	45	2	11331379
Pubmed	Genetic mapping refines DFNB3 to 17p11.2, suggests multiple alleles of DFNB3, and supports homology to the mouse model shaker-2.	KCNJ18 KCNJ12	2.45e-05	6	45	2	9529344
Pubmed	International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels.	KCNN2 KCNN3	4.56e-05	8	45	2	16382103
Pubmed	Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS.	KCNJ18 KCNJ12	4.56e-05	8	45	2	27930290
Pubmed	G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase.	KCNJ5 KCNJ9	5.86e-05	9	45	2	12297500
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	RUFY2 ZDHHC5 RAB23 ARFGEF1 SLC12A2 ATP2B1	8.85e-05	569	45	6	30639242
Pubmed	A physical map of the mouse shaker-2 region contains many of the genes commonly deleted in Smith-Magenis syndrome (del17p11.2p11.2).	KCNJ18 KCNJ12	1.27e-04	13	45	2	10049592
Pubmed	HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation.	KCNN2 KCNN3	1.47e-04	14	45	2	10758170
Pubmed	Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.	KCNJ4 KCNJ12	2.76e-04	19	45	2	15024025
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ZDHHC5 RAB23 SMG1 UROD SLC12A2 ATP2B1	3.13e-04	719	45	6	35337019
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RUFY2 ZDHHC5 DIP2C KIAA0930 GNPDA1	4.29e-04	493	45	5	15368895
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZDHHC5 DIP2C KIAA0930 NUP188 SLC45A3 RYR1 ARHGAP44	5.07e-04	1105	45	7	35748872
Pubmed	Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike.	KCNJ18 KCNJ12	5.63e-04	27	45	2	17273973
Pubmed	Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes.	KCNJ4 KCNJ12	5.63e-04	27	45	2	24550280
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	CAD NUP188 GNPDA1 HK2 ATP2B1	6.17e-04	534	45	5	35032548
Pubmed	Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.	KIFAP3 RYR1	6.96e-04	30	45	2	20080650
Pubmed	Potential genetic modifiers of the cystic fibrosis intestinal inflammatory phenotype on mouse chromosomes 1, 9, and 10.	KCNJ5 KCNJ9	7.43e-04	31	45	2	15921521
Pubmed	Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.	KCNJ18 KCNJ12	7.43e-04	31	45	2	17473172
Pubmed	The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex.	HK2 IFI27 ARHGAP44	8.68e-04	144	45	3	30585266
Pubmed	Ion channel expression in the developing enteric nervous system.	KCNN2 KCNN3	1.06e-03	37	45	2	25798587
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	ATP2B1 RYR1	1.12e-03	38	45	2	30786075
Interaction	SSTR3 interactions	GABRB1 RAB23 KIFAP3 SLC12A2 ATP2B1 KCNJ4 KCNJ9	1.52e-05	393	42	7	int:SSTR3
Interaction	KCNJ18 interactions	KCNJ18 KCNJ5	2.54e-05	4	42	2	int:KCNJ18
Interaction	LIN7B interactions	KCNJ4 RABGAP1L KCNJ12	8.49e-05	41	42	3	int:LIN7B
Cytoband	4p12	GABRB1 GNPDA2	1.77e-04	20	45	2	4p12
Cytoband	Ensembl 112 genes in cytogenetic band chr4p12	GABRB1 GNPDA2	3.01e-04	26	45	2	chr4p12
GeneFamily	Potassium voltage-gated channel subfamily J	KCNJ18 KCNJ4 KCNJ5 KCNJ9 KCNJ12	3.18e-11	16	29	5	276
GeneFamily	Potassium calcium-activated channels	KCNN2 KCNN3	3.71e-05	6	29	2	255
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SIGLEC16 CEACAM20 WFIKKN2	2.14e-03	161	29	3	593
GeneFamily	Solute carriers	SLC12A2 SLC45A3 SLC2A7 SLC25A34	3.46e-03	395	29	4	752
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC45A3 CEACAM20 SVOPL WFIKKN2	1.13e-06	79	44	4	239d34f40c3a96186231f3aabd41c4988af3f372
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC45A3 CEACAM20 SVOPL WFIKKN2	1.13e-06	79	44	4	a60fcbb278ba629af922c53faf58e4d96c537b15
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN3 SLC12A2 SVOPL KCNJ12	1.24e-05	144	44	4	121853910eeea1ea0642b3cc99f9200015480368
ToppCell	Children_(3_yrs)-Immune-mast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DIP2C SLC45A3 CEACAM20 SVOPL	1.31e-05	146	44	4	f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Gfra2_(Zona_Incerta,_ventral_part_(ZIV))\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ECT2L GPR174 SVOPL	1.76e-05	51	44	3	622a588dcf6f70c5e6b7133678c00fc68d70d6b5
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Gfra2_(Zona_Incerta,_ventral_part_(ZIV))-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ECT2L GPR174 SVOPL	1.76e-05	51	44	3	734b7ba494e57a0958999581c805eb90b9bbbd5a
ToppCell	mild-Myeloid-CD14_Monocytes_3\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SIGLEC16 KIAA0930 HK2 IFI27	2.11e-05	165	44	4	a6547bb2c9c40b4878325da19b9def0ef644fa25
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GNPDA1 ATP2B1 KCNJ5 RYR1	2.48e-05	172	44	4	9befd44bce43eb5dc1fe3d2e44608f442cf74a47
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN2 SLC12A2 WFIKKN2 KCNJ12	2.66e-05	175	44	4	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSPAN6 DIP2C SLC45A3 ARHGAP44	2.66e-05	175	44	4	711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN2 SLC12A2 WFIKKN2 KCNJ12	2.66e-05	175	44	4	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB1 KCNN2 KCNN3 SLC25A34	3.74e-05	191	44	4	fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
Drug	sodium	GABRB1 KCNN2 KCNN3 GNPDA1 SLC12A2 ATP2B1 KCNJ4 SLC2A7 KCNJ5 RYR1 KCNJ9 GNPDA2 KCNJ12	1.55e-08	944	44	13	CID000000923
Drug	barium chloride dihydrate	SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.94e-08	43	44	5	CID000025157
Drug	rubidium	SLC12A2 KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.17e-07	61	44	5	CID000105153
Drug	barium	KCNN3 CAD KCNJ4 KCNJ5 KCNJ9 KCNJ12	3.92e-07	148	44	6	CID000104810
Drug	A13108	KCNJ4 KCNJ5 KCNJ12	8.00e-07	10	44	3	CID000062278
Drug	baclofen	GABRB1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.74e-06	191	44	6	CID000002284
Drug	BaCl2	KCNJ4 KCNJ5 KCNJ9 KCNJ12	3.57e-06	54	44	4	CID000025204
Drug	cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine	KCNN2 KCNN3	3.65e-06	2	44	2	ctd:C552889
Drug	verapamil	KCNN2 KCNN3 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	3.90e-06	490	44	8	CID000002520
Drug	CID5255110	KCNJ4 KCNJ5 KCNJ9 KCNJ12	4.45e-06	57	44	4	CID005255110
Drug	diazoxide	KCNN2 KCNN3 KCNJ4 KCNJ5 KCNJ9 KCNJ12	4.73e-06	227	44	6	CID000003019
Drug	AC1Q6RZ6	GNPDA1 HK2 KCNJ4 GNPDA2	5.47e-06	60	44	4	CID000000609
Drug	tetraethylammonium	KCNN2 KCNN3 KCNJ4 KCNJ5 KCNJ9 KCNJ12	5.91e-06	236	44	6	CID000005413
Drug	CsCl	UROD KCNJ4 KCNJ5 RYR1 KCNJ12	6.36e-06	136	44	5	CID000024293
Drug	cyanide	UROD KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	8.99e-06	254	44	6	CID000000768
Drug	4-AP	KCNN2 KCNN3 KCNJ4 KCNJ5 KCNJ9 KCNJ12	9.83e-06	258	44	6	CID000001727
Drug	Thallium	KCNN2 KCNN3 KCNJ4	1.01e-05	22	44	3	ctd:D013793
Drug	Rubidium chromate	SLC12A2 KCNJ4 KCNJ5 KCNJ12	1.26e-05	74	44	4	CID000061605
Drug	2-amino-2-deoxy-D-glucitol 6-phosphate	GNPDA1 GNPDA2	2.18e-05	4	44	2	CID000001554
Drug	Apamin	KCNN2 KCNN3	2.18e-05	4	44	2	ctd:D001030
Drug	pinacidil	KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.40e-05	87	44	4	CID000004826
Drug	cromakalim	KCNJ4 KCNJ5 KCNJ9 KCNJ12	2.51e-05	88	44	4	CID000071191
Drug	1-octen-3-one	PTCHD3 RYR1	7.62e-05	7	44	2	CID000061346
Drug	glibenclamide	KCNN2 KCNN3 KCNJ4 KCNJ5 KCNJ9 KCNJ12	8.83e-05	382	44	6	CID000003488
Drug	AC1Q6RZ4	GNPDA1 HK2 RYR1 GNPDA2	9.32e-05	123	44	4	CID000000719
Drug	K-Cl	UROD SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ12	9.86e-05	567	44	7	CID000004873
Drug	AC1L1G92	UROD RYR1	1.01e-04	8	44	2	CID000003582
Drug	D-glucosamine-6P	GNPDA1 GNPDA2	1.01e-04	8	44	2	CID000121988
Drug	KB-R7943	SLC12A2 ATP2B1 RYR1	1.03e-04	47	44	3	CID004534086
Drug	potassium	KCNN2 KCNN3 SLC12A2 ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.10e-04	1008	44	9	CID000000813
Drug	glucitol-6-phosphate	GNPDA1 HK2 GNPDA2	1.17e-04	49	44	3	CID000000618
Drug	m-7a	UROD RYR1	1.30e-04	9	44	2	CID000029558
Drug	FT T	ARFGEF1 HK2 SLC12A2	1.31e-04	51	44	3	CID000445622
Drug	1 sulfonylurea	KCNJ4 KCNJ5 KCNJ9 KCNJ12	1.67e-04	143	44	4	CID011819083
Drug	clotrimazole	KCNN2 KCNN3 UROD ATP2B1	1.67e-04	143	44	4	CID000002812
Drug	magnesium	KCNN2 CAD HK2 UROD ATP2B1 KCNJ4 KCNJ5 RYR1 KCNJ9 KCNJ12	1.73e-04	1325	44	10	CID000000888
Drug	methanesulfonate	SLC12A2 KCNJ5 RYR1	1.83e-04	57	44	3	CID000006395
Drug	phytochromobilin	UROD PTCHD3	1.99e-04	11	44	2	CID006449958
Drug	chloroquine	UROD KCNJ4 SLC2A7 KCNJ5 KCNJ12	2.27e-04	288	44	5	CID000002719
Drug	ethanedithiol	GNPDA1 GNPDA2	2.38e-04	12	44	2	CID000033645
Drug	bifeprunox	KCNJ5 KCNJ9	2.81e-04	13	44	2	CID000208951
Drug	mildronate	HK2 UROD	2.81e-04	13	44	2	CID000123868
Disease	cesarean section, anxiety	DIP2C OR4L1	6.05e-05	8	44	2	EFO_0005230, EFO_0009636
Disease	uridine diphosphate measurement	KCNN2 PTCHD3	4.06e-04	20	44	2	EFO_0010545
Disease	corpus callosum mid-anterior volume measurement	ZDHHC5 TAAR6	7.45e-04	27	44	2	EFO_0010297
Disease	Paroxysmal atrial fibrillation	KCNN2 KCNN3 KCNJ5	1.64e-03	156	44	3	C0235480
Disease	Persistent atrial fibrillation	KCNN2 KCNN3 KCNJ5	1.64e-03	156	44	3	C2585653
Disease	familial atrial fibrillation	KCNN2 KCNN3 KCNJ5	1.64e-03	156	44	3	C3468561
Disease	Atrial Fibrillation	KCNN2 KCNN3 KCNJ5	1.76e-03	160	44	3	C0004238
Disease	migraine disorder	DIP2C ATP2B1 RABGAP1L TAAR6	1.95e-03	357	44	4	MONDO_0005277
Disease	cardioembolic stroke	KCNN2 KCNN3 KCNJ5	2.09e-03	170	44	3	EFO_1001976

Protein segments in the cluster

Peptide	Gene	Start	Entry
NIVEEMVNIVVGDMG	ARFGEF1	331	Q9Y6D6
MVNIVVGDMGEGTTI	ARFGEF1	336	Q9Y6D6
VASGEVVEVMEGSSM	CEACAM20	171	Q6UY09
EMVMESVKAGVVSVV	ECT2L	301	Q008S8
VMEGSGRMVVTAVGV	ATP2B1	266	P20020
MEVAIKMVVVGNGAV	RAB23	6	Q9ULC3
VIGSGLTMEEMIFEV	EYA3	336	Q99504
EIVVILEGMVEATGM	KCNJ9	271	Q92806
IVVILEGMVEATAMT	KCNJ4	286	P48050
VVVILEGMVEATGMT	KCNJ5	301	P48544
DILVVPQALGMEVTM	UROD	86	P06132
VVIGGVVAMAAVPMV	IFI27	36	P40305
VVILEGMVEATAMTT	KCNJ12	296	Q14500
VPTMALTVGVGTVMD	GNPDA1	181	P46926
LTVGVGTVMDAREVM	GNPDA1	186	P46926
GTVMDAREVMILITG	GNPDA1	191	P46926
GMVGTMTEVFVIVGV	SLC2A7	166	Q6PXP3
FGMFGIVVMVIETEL	KCNN2	141	Q9H2S1
DMTVGEGEMVCVELV	KIAA0930	176	Q6ICG6
IDIVAVVNDTVGTMM	HK2	201	P52789
GMFGIVVMVIETELS	KCNN3	291	Q9UGI6
GATVMGNILIMVTVT	OR4L1	36	Q8NH43
VDVGMRIDVASIDMV	GABRB1	61	P18505
QSVVMMTIGELIGFV	GPR174	181	Q9BXC1
MTVAVDMVVTEVVEP	RABGAP1L	391	Q5R372
EITVMTEGLAVIMTP	OR1L1	246	Q8NH94
LVFVVGKMDGLMVVS	DIP2C	786	Q9Y2E4
VPTMALTVGVGTVMD	GNPDA2	181	Q8TDQ7
LTVGVGTVMDAREVM	GNPDA2	186	Q8TDQ7
GTVMDAREVMILITG	GNPDA2	191	Q8TDQ7
TVMEVMVNVLGGGES	RYR1	2206	P21817
LEVVIMIGTVSMDDS	KIFAP3	566	Q92845
ILGVGVDDMFIMISA	PTCHD3	451	Q3KNS1
VVGGVEMVLLIAMAF	OR4F3;	106	Q6IEY1
VVILEGMVEATAMTT	KCNJ18	296	B7U540
LMMEEEGAVIVGLLV	RUFY2	141	Q8WXA3
VGVTVMPFSMVRTVE	TAAR6	81	Q96RI8
AGGMISSIAVVVVMT	SLC25A34	211	Q6PIV7
GNELEVTIMMVVEAL	SMG1	1066	Q96Q15
RLSEAIVTVIMGMGV	TMEM69	181	Q5SWH9
MDVVVSLVTIMLDTG	PI4KAP2	521	A4QPH2
EMMTTVSLQIVGIIE	ARHGAP44	421	Q17R89
VGVEEKFMTMVLGIG	SLC45A3	46	Q96JT2
FLIMGSTGVVEAMEI	SVOPL	51	Q8N434
STGVVEAMEIMLIAV	SVOPL	56	Q8N434
GIGLSVLVIMMATVV	SLC12A2	316	P55011
TVINIMGIGVDTIDM	NUP188	776	Q5SRE5
VMTIIESEMGVVAGI	TSPAN6	201	O43657
VIMGEEVEPVGLMTG	CAD	1241	P27708
EELSGVRTAVTMAVM	ZDHHC5	176	Q9C0B5
PMTGVVLVAVGEVAM	SIGLEC16	431	A6NMB1
TVSEMPLIIMGEVDG	WFIKKN2	521	Q8TEU8