Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal anchor activity

ANK2 ANK3 MAP1A

5.51e-0524623GO:0008093
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RUNDC3A DENND1B MYCBP2 ARHGEF10 ARFGAP3 TBC1D2 FGD6 SOS1

1.66e-04507628GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RUNDC3A DENND1B MYCBP2 ARHGEF10 ARFGAP3 TBC1D2 FGD6 SOS1

1.66e-04507628GO:0030695
GeneOntologyMolecularFunctionphosphorylation-dependent protein binding

ANK2 ANK3

4.20e-0410622GO:0140031
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF3B RSF1 NAV1 DHX32 SMARCAD1 FANCM ATP2B1

4.22e-04441627GO:0016887
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DENND1B MYCBP2 ARHGEF10 FGD6 SOS1

7.51e-04231625GO:0005085
GeneOntologyMolecularFunctioncaspase binding

RIPK2 BFAR

1.11e-0316622GO:0089720
GeneOntologyBiologicalProcessmicrotubule-based movement

ROPN1L KIF3B ANK3 MAP1A VPS13A CABS1 DNAI4 AGTPBP1 JHY

1.19e-05493609GO:0007018
GeneOntologyBiologicalProcessanterograde axonal transport

KIF3B ANK3 MAP1A AGTPBP1

1.97e-0555604GO:0008089
GeneOntologyBiologicalProcessmicrotubule-based process

ROPN1L KIF3B ANK3 MAP1A ARHGEF10 PPP1R12A VPS13A CABS1 NAV1 DNAI4 AGTPBP1 JHY

4.44e-0510586012GO:0007017
GeneOntologyBiologicalProcessaxonal transport

KIF3B ANK3 MAP1A AGTPBP1

6.74e-0575604GO:0098930
GeneOntologyBiologicalProcessregulation of sprouting of injured axon

PUM2 TNR

8.27e-055602GO:0048686
GeneOntologyBiologicalProcessmicrotubule-based transport

ROPN1L KIF3B ANK3 MAP1A AGTPBP1 JHY

9.23e-05253606GO:0099111
GeneOntologyBiologicalProcesssprouting of injured axon

PUM2 TNR

1.24e-046602GO:0048682
GeneOntologyBiologicalProcessbranchiomotor neuron axon guidance

PLXNA3 MYCBP2

1.73e-047602GO:0021785
GeneOntologyBiologicalProcessaxo-dendritic transport

KIF3B ANK3 MAP1A AGTPBP1

1.91e-0498604GO:0008088
GeneOntologyCellularComponentaxon initial segment

ANK3 MAP1A NAV1

8.59e-0529623GO:0043194
GeneOntologyCellularComponentspectrin-associated cytoskeleton

ANK3 SPTA1

3.07e-049622GO:0014731
GeneOntologyCellularComponentcell body

PITPNM2 PDE1A SNCAIP MAP1A KCNJ6 VPS13A ACTG2 PUM2 ATP2B1 SOS1

3.77e-049296210GO:0044297
DomainZU5

ANK2 ANK3

3.85e-049622SM00218
DomainZU5

ANK2 ANK3

4.80e-0410622PS51145
DomainZU5

ANK2 ANK3

7.00e-0412622PF00791
DomainZU5_dom

ANK2 ANK3

7.00e-0412622IPR000906
DomainRhoGEF

ARHGEF10 FGD6 SOS1

1.50e-0368623SM00325
DomainRhoGEF

ARHGEF10 FGD6 SOS1

1.63e-0370623PF00621
DomainDH_2

ARHGEF10 FGD6 SOS1

1.63e-0370623PS50010
DomainDH-domain

ARHGEF10 FGD6 SOS1

1.70e-0371623IPR000219
Domain-

ARHGEF10 FGD6 SOS1

1.70e-03716231.20.900.10
DomainDEATH

ANK2 ANK3

3.61e-0327622SM00005
Domain-

ANK2 ANK3 RIPK2

3.66e-03936231.10.533.10
Domain-

MYCBP2 SYTL5 RSF1 BFAR FGD6 CNOT4

3.68e-034496263.30.40.10
DomainZnf_RING/FYVE/PHD

MYCBP2 SYTL5 RSF1 BFAR FGD6 CNOT4

4.10e-03459626IPR013083
DomainSpectrin_repeat

SPTA1 EVPL

4.16e-0329622IPR002017
DomainDEATH-like_dom

ANK2 ANK3 RIPK2

4.36e-0399623IPR011029
DomainIg_E-set

PLXNA3 MYCBP2 KCNJ6

5.00e-03104623IPR014756
DomainSpectrin/alpha-actinin

SPTA1 EVPL

5.04e-0332622IPR018159
DomainSPEC

SPTA1 EVPL

5.04e-0332622SM00150
DomainDeath

ANK2 ANK3

5.36e-0333622PF00531
DomainAnk_2

SNCAIP ANK2 ANK3 PPP1R12A

5.66e-03215624PF12796
DomainGPS

ADGRF5 ADGRL3

5.68e-0334622SM00303
DomainGPCR_2_secretin-like_CS

ADGRF5 ADGRL3

5.68e-0334622IPR017983
DomainHELICASE_CTER

DHX32 SMARCAD1 FANCM

5.70e-03109623PS51194
DomainHELICASE_ATP_BIND_1

DHX32 SMARCAD1 FANCM

5.70e-03109623PS51192
DomainHelicase_ATP-bd

DHX32 SMARCAD1 FANCM

5.84e-03110623IPR014001
DomainGPS

ADGRF5 ADGRL3

6.01e-0335622PF01825
DomainGPS

ADGRF5 ADGRL3

6.35e-0336622PS50221
DomainGPS

ADGRF5 ADGRL3

6.70e-0337622IPR000203
DomainAnk

SNCAIP ANK2 ANK3 PPP1R12A

6.94e-03228624PF00023
DomainDeath_domain

ANK2 ANK3

7.06e-0338622IPR000488
DomainZnf_FYVE

SYTL5 FGD6

7.06e-0338622IPR000306
DomainDEATH_DOMAIN

ANK2 ANK3

7.06e-0338622PS50017
DomainGDS_CDC24_CS

ARHGEF10 SOS1

7.42e-0339622IPR001331
DomainG_PROTEIN_RECEP_F2_1

ADGRF5 ADGRL3

7.80e-0340622PS00649
DomainGPCR_2_extracellular_dom

ADGRF5 ADGRL3

7.80e-0340622IPR001879
DomainZF_FYVE

SYTL5 FGD6

7.80e-0340622PS50178
DomainG_PROTEIN_RECEP_F2_3

ADGRF5 ADGRL3

7.80e-0340622PS50227
Domain-

SNCAIP ANK2 ANK3 PPP1R12A

9.27e-032486241.25.40.20
DomainANK

SNCAIP ANK2 ANK3 PPP1R12A

9.66e-03251624SM00248
DomainANK_REPEAT

SNCAIP ANK2 ANK3 PPP1R12A

9.92e-03253624PS50088
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

ANK2 ANK3 SPTA1 SCN7A

2.68e-0631454M877
PathwayWP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS

ANK3 KCNJ6 ATP2B1 EPB41L1

9.28e-0642454M39703
PathwayWP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS

ANK3 KCNJ6 ATP2B1 EPB41L1

9.28e-0642454MM15822
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

WWC2 DENND1B MYCBP2 ARHGEF10 CEP112 PPP1R12A RIPK2 NAV1 FGD6 ATP2B1 CNOT4 EPB41L1

3.41e-08861621236931259
Pubmed

Analysis of erythrocyte and platelet membrane proteins in various forms of beta-thalassemia.

ANK2 SPTA1 GSN

1.07e-07662315310273
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF3B NAV1 PUM2 SMARCAD1 AHCYL2 ADGRL3 EPB41L1 AGTPBP1

6.39e-0740762812693553
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

ANK2 ANK3 SPTA1

6.42e-071062322159418
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

PITPNM2 ANK2 ANK3 MAP1A TNR EPB41L1 GSN

7.02e-0728162728706196
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FAM133B PLXNA3 RUNDC3A ANK2 CEP112 PPP1R12A SPTA1 RSF1 NOC3L VPS13A ACTG2 AHCYL2 ATP2B1

1.27e-061442621335575683
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ANK2 MAP1A MYCBP2 AHCYL2 ADGRL3 EPB41L1 SOS1

2.85e-0634762717114649
Pubmed

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

ANK2 ANK3

3.13e-06262211781319
Pubmed

Unique cerebellar phenotype combining granule and Purkinje cell loss: morphological evidence for weaver* pcd double mutant mice.

KCNJ6 AGTPBP1

3.13e-0626222027034
Pubmed

Structural basis of diverse membrane target recognitions by ankyrins.

ANK2 ANK3

3.13e-06262225383926
Pubmed

Serotonin-immunoreactivity in the cerebellum of two neurological mutant mice and the corresponding wild-type genetic stocks.

KCNJ6 AGTPBP1

3.13e-0626221781951
Pubmed

Modulation of GABA(A) receptor subunit mRNA levels in olivocerebellar neurons of purkinje cell degeneration and weaver mutant mice.

KCNJ6 AGTPBP1

3.13e-06262210800965
Pubmed

Lesion-specific pattern of immunocytochemical distribution of growth-associated protein B-50 (GAP-43) in the cerebellum of Weaver and PCD-mutant mice: lack of B-50 involvement in neuroplasticity of Purkinje cell terminals?

KCNJ6 AGTPBP1

3.13e-0626227932867
Pubmed

Plasticity of GABAergic terminals in Deiters' nucleus of weaver mutant and normal mice: a quantitative light microscopic study.

KCNJ6 AGTPBP1

3.13e-0626221446244
Pubmed

A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption.

ANK3 ARHGEF10

3.13e-06262231372216
Pubmed

The cleavage of host cell proteins by HIV-1 protease.

MAP1A SPTA1 ACTG2

3.60e-06176238997639
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PITPNM2 SERPINB5 ANK2 ANK3 MAP1A MYCBP2 ARFGAP3 NAV1 AHCYL2 ADGRL3 EPB41L1

4.87e-061139621136417873
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 ANK2 ANK3 MAP1A PPP1R12A SPTA1 NAV1 TNR ATP2B1 EPB41L1 GSN AGTPBP1

7.21e-061431621237142655
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF3B ANK2 ANK3 MYCBP2 PPP1R12A RIPK2 NAV1 TNR EPB41L1 GSN

7.38e-06963621028671696
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

ANK2 ANK3 MAP1A AHCYL2 TNR ATP2B1 EPB41L1

7.57e-0640362730562941
Pubmed

Human ankyrins and their contribution to disease biology: An update.

ANK2 ANK3

9.37e-06362233410423
Pubmed

Calbindin D-28k in the lateral vestibular nucleus of mutant mice as a tool to reveal Purkinje cell plasticity.

KCNJ6 AGTPBP1

9.37e-0636228177535
Pubmed

Cbln1 binds to specific postsynaptic sites at parallel fiber-Purkinje cell synapses in the cerebellum.

KCNJ6 AGTPBP1

9.37e-06362219200061
Pubmed

DNA fragmentation and activation of c-Jun in the cerebellum of mutant mice (weaver, Purkinje cell degeneration).

KCNJ6 AGTPBP1

9.37e-0636228541477
Pubmed

Transplantation of cerebellar anlagen to hosts with genetic cerebellocortical atrophy.

KCNJ6 AGTPBP1

9.37e-0636223619071
Pubmed

Pro-thyrotropin-releasing hormone concentrations in the brain of ataxic mice.

KCNJ6 AGTPBP1

9.37e-0636222123001
Pubmed

Vestibular ganglion neurons survive the loss of their cerebellar targets.

KCNJ6 AGTPBP1

9.37e-0636229926858
Pubmed

Expression of c-kit, a proto-oncogene of the murine W locus, in cerebella of normal and neurological mutant mice: immunohistochemical and in situ hybridization analysis.

KCNJ6 AGTPBP1

9.37e-0636221282111
Pubmed

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

ANK2 ANK3

9.37e-06362215611082
Pubmed

Regulation of mitotic spindle formation by the RhoA guanine nucleotide exchange factor ARHGEF10.

KIF3B ARHGEF10

9.37e-06362219635168
Pubmed

Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.

ANK2 ANK3

9.37e-06362234289389
Pubmed

NeuN, a neuronal specific nuclear protein in vertebrates.

KCNJ6 AGTPBP1

1.87e-0546221483388
Pubmed

GABAA/benzodiazepine receptor alpha 6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: expression in developing and mutant mice.

KCNJ6 AGTPBP1

1.87e-0546228132866
Pubmed

EAPII interacts with ETS1 and modulates its transcriptional function.

FLI1 TDP2

1.87e-05462212743594
Pubmed

[Elevated immunoreactive-somatostatin levels in the brain of ataxic mutant mice].

KCNJ6 AGTPBP1

1.87e-0546222901364
Pubmed

Developmental expression and intracellular location of P400 protein characteristic of Purkinje cells in the mouse cerebellum.

KCNJ6 AGTPBP1

1.87e-0546222707487
Pubmed

Ataxia-ameliorating effects of YM-14673, a potent analog of thyrotropin releasing hormone, in ataxic mutant mice.

KCNJ6 AGTPBP1

1.87e-0546228013566
Pubmed

Cellular distribution of the RNA transcripts of a newly discovered gene in the brain of normal, weaver, Purkinje cell degeneration and reeler mutant mice as evidenced by in situ hybridization histochemistry.

KCNJ6 AGTPBP1

1.87e-0546228326827
Pubmed

The Purkinje cell class may extend beyond the cerebellum.

KCNJ6 AGTPBP1

1.87e-0546222077109
Pubmed

CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.

ANK2 ANK3

3.12e-05562225950943
Pubmed

Levels of somatostatin and cholecystokinin in the brain of ataxic mutant mice.

KCNJ6 AGTPBP1

3.12e-0556228100981
Pubmed

Glial ankyrins facilitate paranodal axoglial junction assembly.

ANK2 ANK3

3.12e-05562225362471
Pubmed

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.

ANK2 SPTA1

3.12e-05562229720258
Pubmed

An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.

ANK2 ANK3

3.12e-05562219109891
Pubmed

In vivo assembly of the axon initial segment in motor neurons.

ANK2 ANK3

4.67e-05662223728480
Pubmed

Expression of the metabotropic glutamate receptor mGluR1 alpha and the ionotropic glutamate receptor GluR1 in the brain during the postnatal development of normal mouse and in the cerebellum from mutant mice.

KCNJ6 AGTPBP1

4.67e-0566228230318
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PITPNM2 DENND1B ANK3 MYCBP2 PPP1R12A NAV1 AHCYL2 SPIDR TRRAP ATP2B1 EPB41L1

5.81e-051489621128611215
Pubmed

Vestibular ganglion neurons survive hair cell defects in jerker, shaker, and Varitint-waddler mutants and downregulate calretinin expression.

KCNJ6 AGTPBP1

6.53e-05762217663432
Pubmed

Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.

ANK2 ANK3

6.53e-0576227495297
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

WWC2 MYCBP2 TBC1D2 PUM2 SMARCAD1 TRRAP AGTPBP1 SOS1

6.80e-0577462815302935
Pubmed

Germline gain-of-function mutations in SOS1 cause Noonan syndrome.

PAG1 SOS1

8.69e-05862217143285
Pubmed

Interleukin-1 hyperproduction by in vitro activated peripheral macrophages from cerebellar mutant mice.

KCNJ6 AGTPBP1

8.69e-0586222230805
Pubmed

Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.

ANK2 MAP1A EPB41L1

9.37e-054962320471030
Pubmed

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.

ANK3 NAV1

1.12e-04962226671463
Pubmed

Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.

ANK2 ANK3

1.12e-04962229867141
Pubmed

Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry.

KCNJ6 AGTPBP1

1.12e-04962216499884
Pubmed

Glutamate dehydrogenase in cerebellar mutant mice: gene localization and enzyme activity in different tissues.

KCNJ6 AGTPBP1

1.12e-0496222293612
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

RUNDC3A PPP1R12A SPTA1 TNR ATP2B1 EPB41L1

1.18e-0443062632581705
Pubmed

Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair.

SPIDR FANCM

1.39e-041062223509288
Pubmed

Peripheral macrophage abnormalities in mutant mice with spinocerebellar degeneration.

KCNJ6 AGTPBP1

1.39e-04106221565842
Pubmed

Non-viral cellular substrates for human immunodeficiency virus type 1 protease.

SPTA1 ACTG2

1.39e-04106221991513
Pubmed

Gelsolin activity controls efficient early HIV-1 infection.

ACTG2 GSN

1.39e-041062223575248
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

PDE1A SPTA1 ATP2B1 GSN

1.41e-0414762416959763
Pubmed

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.

ANK2 ADGRF5 ATP2B1

1.72e-046062319075228
Pubmed

The protein interaction landscape of the human CMGC kinase group.

NOC3L NAV1 ZFP14 AHCYL2 TDP2 EPB41L1 JHY

2.34e-0469562723602568
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ANK2 ANK3 MYCBP2 ARHGEF10 NOC3L VPS13A SMARCAD1 ATP2B1 EPB41L1 AGTPBP1

2.80e-041487621033957083
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MAP1A MYCBP2 PPP1R12A PUM2 TDP2 GSN AGTPBP1

3.00e-0472462736232890
Pubmed

Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.

ANK2 ANK3

3.23e-041562230562487
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

MAP1A MYCBP2 TRRAP

3.46e-047662327542412
Pubmed

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.

ANK2 AHCYL2 TNR ATP2B1 EPB41L1

3.60e-0434162529791485
Pubmed

The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue.

MAP1A FGD6 AGTPBP1

3.87e-047962325921334
Pubmed

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism.

NAV1 ATP2B1 TDP2

4.17e-048162332060556
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ANK2 ANK3 MYCBP2 ARHGEF10 KCNJ6 SMARCAD1 TDP2 AGTPBP1 SOS1

4.34e-04128562935914814
Pubmed

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.

ANK2 ANK3

4.70e-041862237321992
Pubmed

Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.

ANK2 ANK3

4.70e-041862231910261
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

ANK2 ANK3 MAP1A SCN7A ATP2B1 EPB41L1

4.77e-0455862635063084
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

PITPNM2 WWC2 DENND1B ARFGAP3 AHCYL2 TRUB1 CNOT4 AGTPBP1

4.97e-04103862826673895
Pubmed

Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation.

PITPNM2 GSN

5.24e-041962221118511
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

WWC2 ANK3 MYCBP2 NOC3L VPS13A ATP2B1 EPB41L1 AGTPBP1

5.33e-04104962827880917
Pubmed

Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.

ACTG2 GSN

7.06e-042262216526095
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MYCBP2 ADGRF5 AHCYL2

7.71e-0410062310048485
Pubmed

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

ANK2 ANK3 PPP1R12A GSN

8.08e-0423362429518331
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

KIF3B ARHGEF10 EPB41L1

8.64e-041046239205841
Pubmed

Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.

PITPNM2 MYCBP2

9.14e-042562212522145
Pubmed

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

SPTA1 SOS1

9.14e-04256228493579
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

PAG1 ANK3 ARHGEF10 ATP2B1 EPB41L1

9.32e-0442162536976175
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ANK3 MAP1A SMARCAD1 ADGRL3 SOS1

1.02e-0343062535044719
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

ANK2 ANK3 EPB41L1 GSN

1.06e-0325162427507650
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRF5 ADGRL3

1.23e-032962215203201
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

PPP1R12A TBC1D2 EVPL

1.24e-0311862330979931
Pubmed

Global landscape of HIV-human protein complexes.

FAM133B PPP1R12A PUM2 AHCYL2 ATP2B1

1.34e-0345762522190034
Pubmed

LZTR1 is a regulator of RAS ubiquitination and signaling.

SPTA1 ATP2B1 EPB41L1

1.54e-0312762330442766
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRF5 ADGRL3

1.59e-033362225713288
Pubmed

HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.

CEP112 TRRAP

1.69e-033462225925205
Pubmed

A human MAP kinase interactome.

ANK3 MAP1A NAV1 EVPL SOS1

1.76e-0348662520936779
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

ARHGEF10 NAV1 TRRAP FGD6 ATP2B1 EPB41L1

1.76e-0371962635337019
InteractionPPP1R9B interactions

ANK2 ANK3 MAP1A MYCBP2 PPP1R12A NOC3L NAV1 AHCYL2 TNR ATP2B1 EPB41L1

2.87e-066266211int:PPP1R9B
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF10 FGD6 SOS1

3.58e-0466383722
GeneFamilyAnkyrin repeat domain containing

SNCAIP ANK2 ANK3 PPP1R12A

1.62e-03242384403
CoexpressionSHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4

ARHGEF10 CEP112 EVPL ADGRF5 AHCYL2 SPIDR EPB41L1

4.22e-07197627M12824
CoexpressionGSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN

PAG1 DENND1B ANK3 FGD6 ATP2B1 NDFIP1

7.03e-06196626M7565
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

MYCBP2 PPP1R12A VPS13A PUM2 TRRAP ATP2B1 CNOT4 SOS1

1.37e-05466628M13522
CoexpressionZHONG_PFC_C5_BCL11B_CALB2_POS_INP

RUNDC3A ANK3 NAV1

1.88e-0522623M39085
CoexpressionCUI_TCF21_TARGETS_2_DN

FLI1 WWC2 PAG1 SNCAIP SCN7A VPS13A PUM2 ADGRF5 ADGRL3 GSN

2.96e-058546210M1533
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

MYCBP2 ARHGEF10 PPP1R12A VPS13A PUM2 SPIDR TRRAP ATP2B1 CNOT4 SOS1

3.02e-058566210M4500
CoexpressionCUI_TCF21_TARGETS_2_DN

FLI1 WWC2 PAG1 SNCAIP SCN7A VPS13A PUM2 ADGRF5 ADGRL3 GSN

4.12e-058886210MM1018
CoexpressionGSE37301_PRO_BCELL_VS_CD4_TCELL_DN

FAM133B PLXNA3 VPS13A RIPK2 TXK

4.51e-05165625M8907
CoexpressionCARRILLOREIXACH_MRS3_VS_LOWER_RISK_HEPATOBLASTOMA_DN

PAG1 ANK3 ARHGEF10 PPP1R12A JHY

4.91e-05168625M45039
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

PLXNA3 PDE1A RUNDC3A ANK2 ANK3 MYCBP2 NAV1 ATP2B1 ADGRL3 EPB41L1 AGTPBP1

5.06e-0511066211M39071
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

PLXNA3 PDE1A RUNDC3A ANK2 ANK3 KCNJ6 NAV1 EPB41L1

6.79e-05584628M39068
CoexpressionGOZGIT_ESR1_TARGETS_DN

PLXNA3 DENND1B ANK3 SYTL5 TBC1D2 AHCYL2 CNOT4 EPB41L1 GSN

9.16e-05786629M10961
CoexpressionGSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP

PAG1 MYCBP2 TRRAP AGTPBP1 TXK

1.12e-04200625M387
CoexpressionBUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP

PLXNA3 CEP112 ARFGAP3 RSF1 RIPK2 FGD6 ATP2B1 CNOT4 SOS1

1.29e-04822629M6782
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 SCN7A NAV1 ADGRF5 ATP2B1 ADGRL3

2.65e-07190626d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellControl-B_memory-3|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FLI1 PAG1 ANK3 FGD6 ATP2B1 GSN

3.08e-07195626135234f068da3e8db7213b53c09ed6d1d0cdc351
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FAM133B PAG1 SNCAIP ANK3 VPS13A TXK

3.27e-0719762657ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2|World / Primary Cells by Cluster

ANK2 ANK3 KCNJ6 TNR ATP2B1 ADGRL3

3.47e-07199626f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV|World / Primary Cells by Cluster

ANK2 ANK3 KCNJ6 TNR ATP2B1 ADGRL3

3.47e-07199626e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

PDE1A SNCAIP SWT1 CEP112 SCN7A

3.51e-061666257286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

PDE1A SNCAIP SWT1 CEP112 SCN7A

3.51e-061666257c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE1A SCN7A NAV1 ADGRL3 GSN

5.50e-06182625fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PDE1A MAP1A SCN7A ACTG2 ADGRL3

5.65e-06183625d04deef7cd4e1738227a6593b84874ce0168c773
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FLI1 ARHGEF10 ADGRF5 ADGRL3

6.78e-06190625474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A ANK2 CEP112 SCN7A GSN

6.78e-0619062596a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PITPNM2 FLI1 ARHGEF10 NAV1 ADGRF5

7.32e-06193625f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PAG1 SNCAIP ANK3 VPS13A TXK

7.32e-061936259337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 SNCAIP NAV1 ADGRF5 GSN

7.32e-061936256a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FLI1 NAV1 ADGRF5 ADGRL3

7.50e-0619462543f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FLI1 NAV1 ADGRF5 ADGRL3

7.50e-061946251d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

ROPN1L ANK3 CEP112 DNAI4 ADGRF5

7.69e-06195625fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NAV1 ADGRF5 GSN AGTPBP1

7.69e-061956256bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

ROPN1L ANK3 CEP112 DNAI4 ADGRF5

7.69e-06195625eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-41|World / Primary Cells by Cluster

PAG1 PDE1A ANK3 KCNJ6 NAV1

7.89e-06196625dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 SNCAIP NAV1 ADGRF5 GSN

7.89e-06196625b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A DENND1B ANK2 ANK3 EPB41L1

7.89e-06196625eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 SNCAIP NAV1 ADGRF5 GSN

7.89e-06196625145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 SNCAIP NAV1 ADGRF5 GSN

7.89e-06196625d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellControl-B_memory-3|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FLI1 PAG1 ANK3 FGD6 GSN

8.08e-06197625b86385c6c1d52ef4e3d855004d77afab61556978
ToppCellMild/Remission-B_memory-3|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PAG1 ANK3 FGD6 ATP2B1 GSN

8.49e-06199625493d043beef70b60338cc199db82592cdc6e635d
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 FLI1 ADGRF5 FGD6 ADGRL3

8.70e-06200625dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellSigmoid-ILC|Sigmoid / Region, Cell class and subclass

PITPNM2 TREH RIPK2 TNR TXK

8.70e-06200625dfb06821f1019833f5d81f9c93808219b5fef407
ToppCellSigmoid-(3)_ILC|Sigmoid / shred on region, Cell_type, and subtype

PITPNM2 TREH RIPK2 TNR TXK

8.70e-06200625a7326c43987a5eb4f4f5b48c4252cf4870432e5d
ToppCellSigmoid-(3)_ILC-(30)_ILC|Sigmoid / shred on region, Cell_type, and subtype

PITPNM2 TREH RIPK2 TNR TXK

8.70e-06200625c39de94623383da7b2b260eb016ddaa5da7f4350
ToppCellSigmoid-ILC-ILC|Sigmoid / Region, Cell class and subclass

PITPNM2 TREH RIPK2 TNR TXK

8.70e-062006254ac1e6d7f358003e2448eb69e545772cd261c55f
ToppCellBronchial-10x5prime-Hematologic-Erythrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RUNDC3A SPTA1 ADGRL3 TXK

2.88e-0512662465c7c0e4cfb5ac58d80b4034d42e9f662116e0d3
ToppCellBronchial-10x5prime-Hematologic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RUNDC3A SPTA1 ADGRL3 TXK

2.88e-05126624b6482ef18e6d9e12ba4810ce7845f9f991cb95bc
ToppCellBronchial-10x5prime-Hematologic-Erythrocyte-Erythrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RUNDC3A SPTA1 ADGRL3 TXK

2.88e-0512662412f3d0f60db462f2a9799b3a06005bc871670760
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PDE1A NOC3L DNAI4 TRUB1

6.15e-051536249f0607a88d5f8a2c128a2ff64dfbc986212f13b2
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SCN7A AHCYL2 TXK

6.31e-0515462437765512dfae557b9f6eb30a29463b93682a4404
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PAG1 PPP1R12A E2F7 ADGRF5

6.63e-051566244877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PAG1 PPP1R12A E2F7 ADGRF5

6.63e-051566241d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

WWC2 ANK3 KCNJ6 ADGRF5

7.14e-051596248680b054622f573a82b1625fb93c2d5db81d1034
ToppCellsevere_influenza-CD8+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

PITPNM2 ARHGEF10 EVPL TXK

7.50e-0516162482196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHX32 BFAR SPIDR FANCM

8.24e-051656247c771f22b58989572c939ed127e637ec28dc0dca
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK2 ANK3 SCN7A ADGRL3

8.84e-0516862488c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINB5 RUNDC3A TREH TRUB1

9.04e-05169624daed9083ee05c220365200328c2c50047fe21efd
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PITPNM2 WWC2 PDE1A ANK3

9.25e-05170624a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NAV1 ADGRF5 TNR

9.90e-05173624afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE1A KCNJ6 ADGRF5 ADGRL3

1.01e-04174624b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE1A KCNJ6 ADGRF5 ADGRL3

1.01e-0417462471730503be3d9c839c4c9e950145e2101d682a1c
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE1A KCNJ6 ADGRF5 ADGRL3

1.01e-04174624ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE1A KCNJ6 ADGRF5 ADGRL3

1.01e-04174624cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

E2F7 DNAI4 ADGRF5 ADGRL3

1.06e-0417662427e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

PDE1A KCNJ6 ACTG2 ADGRL3

1.06e-041766242015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 EVPL FANCM ADGRL3

1.15e-04180624da723df348d7b8449bb1124f23fe6fa706412adb
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PITPNM2 FLI1 NAV1 ADGRF5

1.15e-04180624d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellSevere-B_memory-3|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PAG1 ANK3 ATP2B1 GSN

1.15e-0418062490b812c5450359b1745b413421b71e291c97086a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 ANK3 NDFIP1 TXK

1.15e-04180624f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

ANK3 SCN7A ADGRL3 JHY

1.15e-041806245842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 ANK3 MAP1A TXK

1.15e-04180624d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 EVPL FANCM ADGRL3

1.15e-041806245b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 EVPL FANCM ADGRL3

1.15e-0418062450758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

ANK3 SCN7A ADGRL3 JHY

1.18e-041816247d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 ARHGEF10 ADGRF5 ADGRL3

1.18e-04181624c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 ANK3 NDFIP1 TXK

1.20e-041826249ba85f621a846531a2a7861e9df695d288c9e149
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNCAIP NAV1 ADGRF5 ATP2B1

1.23e-041836243427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDE1A ANK2 ADGRF5 ADGRL3

1.23e-04183624ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 ANK3 NDFIP1 TXK

1.23e-04183624f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 ANK3 NDFIP1 TXK

1.25e-041846245350b58aa9979631228835d11eb45ddf81d08bff
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SCN7A NAV1 ADGRL3 GSN

1.28e-041856248f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

PAG1 PDE1A ADGRF5 ADGRL3

1.28e-04185624ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROPN1L RUNDC3A ADGRF5 JHY

1.28e-041856242a8104f610fa5ce618f8105521616722462a0d42
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITPNM2 RUNDC3A NAV1 ADGRF5

1.28e-04185624bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PDE1A ANK3 ADGRF5 ADGRL3

1.31e-04186624cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

FLI1 ARHGEF10 NAV1 ADGRF5

1.31e-04186624c6075fe84226b370c5139066793844ad33ae2db1
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PAG1 SCN7A ACTG2 ADGRL3

1.31e-04186624cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCelldroplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RUNDC3A SNCAIP ANK2 E2F7

1.34e-041876249c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCellRV-07._Pericyte|World / Chamber and Cluster_Paper

PAG1 SCN7A ADGRF5 EPB41L1

1.34e-04187624dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

FLI1 NAV1 ADGRF5 TNR

1.34e-04187624fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 FLI1 ADGRF5 TNR

1.34e-04187624106f50ad85a92403037214f0e94702230284837f
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RUNDC3A SNCAIP ANK2 E2F7

1.34e-041876249e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PAG1 ANK3 NDFIP1 TXK

1.36e-04188624b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

PDE1A PPP1R12A ACTG2 ADGRL3

1.36e-0418862434e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE1A SCN7A ADGRL3 GSN

1.36e-04188624fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PDE1A TBC1D2 EVPL ADGRF5

1.36e-041886240d86044bc340e3efb90d0022dd299873639d831c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NAV1 ADGRF5 AGTPBP1

1.36e-04188624c2c51c6526defe2600302901159b8abbb58d7595
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

FLI1 ARHGEF10 NAV1 TNR

1.36e-041886243953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 ANK3 NDFIP1 TXK

1.39e-041896249ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGEF10 ADGRF5 TNR ADGRL3

1.39e-04189624b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 ANK3 NDFIP1 TXK

1.39e-041896245a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

PAG1 PPP1R12A ACTG2 ADGRF5

1.39e-041896249c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 ARHGEF10 ADGRF5 ADGRL3

1.42e-04190624812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellPND01-03-samps-Endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FLI1 SCN7A NAV1 ADGRF5

1.42e-041906241357bd4527399d7013ee33272bda7453f472999a
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PLXNA3 ANK3 VPS13A EPB41L1

1.42e-04190624b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FLI1 SCN7A NAV1 ADGRF5

1.42e-041906245130fb325f80f591b9b36beacb8072c4472304f2
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-duct_epithelial_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINB5 ANK3 EVPL FANCM

1.42e-041906245b3f773380aef4773b70f0dbd74992d28e6586c6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ACTG2 ADGRF5 ADGRL3

1.42e-041906245681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RUNDC3A ANK2 KCNJ6 VPS13A

1.42e-04190624b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 DNAI4 NDFIP1 TXK

1.45e-041916249bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANK2 KCNJ6 SCN7A ADGRL3

1.45e-041916245271198116343c07202649889057e5774d7fdde3
ToppCellB_cell_maturation-CD34+_pre-plamsa|B_cell_maturation / Lineage and Cell class

PAG1 SPTA1 NAV1 GSN

1.45e-041916244ee160a863d4fb9c4c9449633b9f337db8871992
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 ANK3 NDFIP1 TXK

1.45e-04191624d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCellControl-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

PPP1R12A ACTG2 ADGRF5 ADGRL3

1.45e-041916242da83c493e60ad0278848957645277d76737a188
Drugtriphosphoinositide

KCNJ6 SCN7A ACTG2 TRRAP EPB41L1 GSN SOS1

9.24e-06273627CID009543520
DrugHaloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A

SNCAIP MAP1A PPP1R12A SPTA1 GSN JHY

1.42e-051936265273_UP
DrugAC1OAGFB

KCNJ6 SPTA1 SCN7A RIPK2 ACTG2 TRRAP EPB41L1 GSN SOS1

1.45e-05539629CID006857345
Drug2-propylpentanoic acid; Up 200; 2000uM; MCF7; HG-U133A

PLXNA3 RUNDC3A ANK2 RIPK2 FGD6 AGTPBP1

1.46e-05194626346_UP
Diseasewhite matter hyperintensity measurement

SNCAIP DENND1B ANK2 EVPL AHCYL2 FGD6

4.15e-05302626EFO_0005665
Diseasecortical surface area measurement

PITPNM2 DENND1B ANK3 MYCBP2 TREH CEP112 NAV1 SMARCAD1 FGD6 CNOT4 SOS1

1.01e-0413456211EFO_0010736
DiseaseCorneal astigmatism

FLI1 TNR NDFIP1

5.78e-0477623EFO_1002040
Diseasecerebral infarction (is_marker_for)

GSN SOS1

7.26e-0419622DOID:3526 (is_marker_for)
Diseasebiological sex

DENND1B ANK3 TNR AGTPBP1

1.41e-03230624PATO_0000047
Diseaselysophosphatidylcholine 20:4 measurement

MYCBP2 KCNJ6

2.07e-0332622EFO_0010363

Protein segments in the cluster

PeptideGeneStartEntry
GTTSVLDTPDYKEDT

CABS1

361

Q96KC9
LDTPDYKEDTSTTET

CABS1

366

Q96KC9
SEDSTIYDLLKDPVS

ARHGEF10

1301

O15013
PEELIYFLDRSSKTS

nan

106

Q9N2K0
PEELIYFLDRSSKTS

nan

106

Q9N2J8
DTETVLKTTGYSDRP

ARFGAP3

386

Q9NP61
PYRTDTLTEYSSKDD

ADGRL3

176

Q9HAR2
YSKKSPVSLDDSDIE

CEP112

191

Q8N8E3
AASSSSLEKSYELPD

ACTG2

231

P63267
SSSEKRYFPESLDSS

DHX32

11

Q7L7V1
EPSESDTARYVTSKI

AGTPBP1

31

Q9UPW5
SSLYEGLEKPESRSS

ATP2B1

1126

P20020
EYVLSSSPADKLDSR

PUM2

96

Q8TB72
RSSSDTSTPEELKIY

KIAA1107

786

Q9UPP5
EEEKLYLQTPTSSER

ANK2

3806

Q01484
KDYSEADGLSERTTP

EPB41L1

66

Q9H4G0
EYLEVTKAPSLDSSL

MAP1A

2216

P78559
SDLEEKSSSLSPYVK

JHY

216

Q6NUN7
ETYETSTPSLSAKEL

KCNJ6

356

P48051
QTDYVDDSTKELSPR

KIAA2026

936

Q5HYC2
SEDSPDILTYSHERK

FANCM

271

Q8IYD8
EYFPTLSSRKLISDE

PLXNA3

176

P51805
IPLIEEASKAETSSY

PDE1A

441

P54750
SSYEKDLTDPISKER

EVPL

1976

Q92817
LPRKRSDSSTYELDT

PITPNM2

661

Q9BZ72
TTLPSYDEAERTKAE

NDFIP1

71

Q9BT67
LTLTEEEFSKTPYTI

BFAR

216

Q9NZS9
YPLSTEKTTISLDEV

E2F7

161

Q96AV8
EDKPLSSESLSESEY

FAM133B

186

Q5BKY9
SSRLSVKEDPSYDSV

FLI1

211

Q01543
ELTAEESLPSYLESS

ANK3

2396

Q12955
EEPSYKRERLTSFTD

DNAI4

201

Q5VTH9
TEALTSAKRYIETDP

GSN

721

P06396
LYESDDSVETRVKTP

DENND1B

546

Q6P3S1
ETKEESYSPSKDRNI

RSF1

466

Q96T23
IKRYSSEVATESPLD

NOC3L

776

Q8WTT2
PKSASSYSDIEEIAT

NAV1

1231

Q8NEY1
TLLEKYTAEPIDDSS

RUNDC3A

41

Q59EK9
TPKTDTGRSYSLDLD

SYTL5

201

Q8TDW5
SYTDSSDDETSPRDK

AHCYL2

161

Q96HN2
RKRKLSSSSEPYEED

SMARCAD1

206

Q9H4L7
DDISYSVTSLKTIPE

SNCAIP

16

Q9Y6H5
SSTKRPYAKELETVD

SERPINB5

106

P36952
RERSKSDSYTLDPDT

MYCBP2

2866

O75592
AETTPLKESYKEEST

SWT1

556

Q5T5J6
RKISYSRIPESETES

SOS1

1061

Q07889
SLSYKSREEDPTLTE

PAG1

296

Q9NWQ8
PETDIDSSCSRYTLK

ADGRF5

416

Q8IZF2
RYDTPIDKPSDSLSI

CNOT4

271

O95628
STKYDPDILKAEIST

WWC2

156

Q6AWC2
SALYTTKETIPEETA

VPS13A

1666

Q96RL7
DVSPLETESYLASLK

ROPN1L

181

Q96C74
PSSIEILEYSSDSEK

SPIDR

176

Q14159
RDEETLELKETYSSL

KIF3B

516

O15066
KEDYELVSTKPTRTS

RIPK2

471

O43353
EELLEKSSYPSSEEK

FGD6

516

Q6ZV73
TVPKDRTSYTLTDLE

TNR

731

Q92752
RPESYSKDVELADTL

TREH

286

O43280
PKTYVDLTNEETTDS

TDP2

81

O95551
ETEPSATSTYLGKDL

SPTA1

811

P02549
SLSTDEELPEKYTQR

TXK

31

P42681
TLDSTGRVTEEKPYD

TRUB1

161

Q8WWH5
DPDRTQYIDSSKLSD

SCN7A

1526

Q01118
ESRYRTNTLSPEKDI

ZFP14

81

Q9HCL3
EPSTSSVASKYEELE

TRRAP

2226

Q9Y4A5
EASSDSIELSPISKY

TBC1D2

546

Q9BYX2
ERKPYSSRLEKDDST

PPP1R12A

916

O14974