Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpattern recognition receptor activity

TLR9 DMBT1

1.95e-0435122GO:0038187
GeneOntologyMolecularFunctioncargo receptor activity

ASGR2 DMBT1

1.15e-0385122GO:0038024
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS12 ADAMTS20

2.27e-03120122GO:0004222
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAMTS12 ADAMTS20

6.17e-03200122GO:0008237
GeneOntologyMolecularFunctioncalcium ion binding

DLK2 UMOD PLA2G5

8.97e-03749123GO:0005509
GeneOntologyMolecularFunctionglycosaminoglycan binding

PLA2G5 DMBT1

1.08e-02268122GO:0005539
GeneOntologyMolecularFunctionsulfur compound binding

PLA2G5 DMBT1

1.55e-02323122GO:1901681
GeneOntologyBiologicalProcessdefense response to Gram-negative bacterium

UMOD TLR9 DMBT1

3.97e-05119123GO:0050829
GeneOntologyBiologicalProcessinnate immune response

UMOD PLA2G5 TLR9 DMBT1 GP2

2.39e-041092125GO:0045087
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

PLXNB3 ADAMTS20 PLA2G5 TLR9 DMBT1

2.93e-041141125GO:0045597
GeneOntologyBiologicalProcessorgan or tissue specific immune response

UMOD GP2

4.37e-0454122GO:0002251
GeneOntologyBiologicalProcessdefense response to symbiont

UMOD PLA2G5 TLR9 DMBT1 GP2

5.12e-041286125GO:0140546
GeneOntologyBiologicalProcessdefense response to other organism

UMOD PLA2G5 TLR9 DMBT1 GP2

7.74e-041407125GO:0098542
GeneOntologyBiologicalProcessresponse to bacterium

RNF5 UMOD TLR9 DMBT1

1.44e-03916124GO:0009617
GeneOntologyBiologicalProcessdefense response to bacterium

UMOD TLR9 DMBT1

1.45e-03405123GO:0042742
GeneOntologyBiologicalProcessERAD pathway

RNF5 UMOD

2.10e-03119122GO:0036503
GeneOntologyBiologicalProcessinflammatory response

ADAMTS12 UMOD PLA2G5 TLR9

2.32e-031043124GO:0006954
GeneOntologyBiologicalProcessneutrophil migration

UMOD GP2

2.50e-03130122GO:1990266
GeneOntologyBiologicalProcesschemokine production

UMOD TLR9

2.69e-03135122GO:0032602
GeneOntologyBiologicalProcessregulation of inflammatory response

ADAMTS12 PLA2G5 TLR9

2.88e-03515123GO:0050727
GeneOntologyBiologicalProcessmacrophage activation

PLA2G5 TLR9

2.89e-03140122GO:0042116
GeneOntologyCellularComponentearly phagosome

PLA2G5 TLR9

2.74e-0514122GO:0032009
GeneOntologyCellularComponentzymogen granule membrane

DMBT1 GP2

5.71e-0520122GO:0042589
GeneOntologyCellularComponentphagocytic vesicle

PLA2G5 TLR9 DMBT1

8.70e-05157123GO:0045335
GeneOntologyCellularComponentzymogen granule

DMBT1 GP2

1.48e-0432122GO:0042588
GeneOntologyCellularComponentcell surface

ASGR2 PLXNB3 UMOD PLA2G5 GP2

2.43e-041111125GO:0009986
GeneOntologyCellularComponentendocytic vesicle

PLA2G5 TLR9 DMBT1

1.20e-03384123GO:0030139
GeneOntologyCellularComponentapical plasma membrane

UMOD TLR9 GP2

2.36e-03487123GO:0016324
GeneOntologyCellularComponentapical part of cell

UMOD TLR9 GP2

4.11e-03592123GO:0045177
GeneOntologyCellularComponentextracellular matrix

ADAMTS12 ADAMTS20 DMBT1

5.48e-03656123GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS12 ADAMTS20 DMBT1

5.52e-03658123GO:0030312
GeneOntologyCellularComponentside of membrane

ASGR2 UMOD GP2

1.21e-02875123GO:0098552
GeneOntologyCellularComponentbasolateral plasma membrane

UMOD TLR9

1.39e-02320122GO:0016323
GeneOntologyCellularComponentsecretory granule membrane

DMBT1 GP2

1.47e-02329122GO:0030667
GeneOntologyCellularComponentbasal plasma membrane

UMOD TLR9

1.69e-02354122GO:0009925
DomainZP_dom_CS

UMOD DMBT1 GP2

2.43e-0810123IPR017977
DomainZP_1

UMOD DMBT1 GP2

7.35e-0814123PS00682
DomainZP_2

UMOD DMBT1 GP2

7.35e-0814123PS51034
DomainZP

UMOD DMBT1 GP2

9.18e-0815123SM00241
DomainZP_dom

UMOD DMBT1 GP2

1.37e-0717123IPR001507
DomainZona_pellucida

UMOD DMBT1 GP2

1.37e-0717123PF00100
DomainADAM_spacer1

ADAMTS12 ADAMTS20

9.50e-0523122IPR010294
DomainADAM_spacer1

ADAMTS12 ADAMTS20

9.50e-0523122PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS12 ADAMTS20

1.04e-0424122IPR013273
DomainPep_M12B_propep

ADAMTS12 ADAMTS20

2.77e-0439122PF01562
DomainPeptidase_M12B_N

ADAMTS12 ADAMTS20

2.77e-0439122IPR002870
DomainDISINTEGRIN_1

ADAMTS12 ADAMTS20

2.91e-0440122PS00427
DomainReprolysin

ADAMTS12 ADAMTS20

2.91e-0440122PF01421
DomainADAM_MEPRO

ADAMTS12 ADAMTS20

2.91e-0440122PS50215
DomainDISINTEGRIN_2

ADAMTS12 ADAMTS20

2.91e-0440122PS50214
DomainPeptidase_M12B

ADAMTS12 ADAMTS20

2.91e-0440122IPR001590
DomainDisintegrin_dom

ADAMTS12 ADAMTS20

3.06e-0441122IPR001762
DomainEGF_3

DLK2 UMOD GP2

3.98e-04235123PS50026
DomainEGF-like_dom

DLK2 UMOD GP2

4.71e-04249123IPR000742
DomainEGF_1

DLK2 UMOD GP2

5.05e-04255123PS00022
DomainEGF-like_CS

DLK2 UMOD GP2

5.41e-04261123IPR013032
DomainEGF_2

DLK2 UMOD GP2

5.65e-04265123PS01186
DomainTSP_1

ADAMTS12 ADAMTS20

7.23e-0463122PF00090
DomainTSP1_rpt

ADAMTS12 ADAMTS20

7.70e-0465122IPR000884
DomainTSP1

ADAMTS12 ADAMTS20

7.70e-0465122PS50092
DomainTSP1

ADAMTS12 ADAMTS20

7.70e-0465122SM00209
Domain-

ADAMTS12 ADAMTS20

1.19e-03811223.40.390.10
DomainMetalloPept_cat_dom

ADAMTS12 ADAMTS20

1.19e-0381122IPR024079
DomainEGF_Ca-bd_CS

DLK2 UMOD

1.70e-0397122IPR018097
DomainZINC_PROTEASE

ADAMTS12 ADAMTS20

1.74e-0398122PS00142
DomainEGF_CA

DLK2 UMOD

1.77e-0399122PS01187
DomainASX_HYDROXYL

DLK2 UMOD

1.81e-03100122PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

DLK2 UMOD

2.03e-03106122IPR000152
DomainEGF_CA

DLK2 UMOD

2.68e-03122122SM00179
DomainEGF-like_Ca-bd_dom

DLK2 UMOD

2.76e-03124122IPR001881
DomainEGF

DLK2 UMOD

2.85e-03126122PF00008
DomainEGF

DLK2 UMOD

9.57e-03235122SM00181
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

RNF5 ASGR2 ADAMTS12 ADAMTS20 UMOD GP2

3.77e-041475116M19806
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 ADAMTS20

4.04e-0439112MM15165
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS12 ADAMTS20

4.04e-0439112M27417
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS12 ADAMTS20

1.23e-0368112M27303
PathwayREACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION

RNF5 ASGR2 UMOD

1.48e-03307113M894
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

ASGR2 ADAMTS12 ADAMTS20 UMOD GP2

2.56e-031389115MM15307
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS12 ADAMTS20

3.11e-03109112MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS12 ADAMTS20

3.23e-03111112M27416
Pubmed

Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.

UMOD GP2

1.09e-07212235273390
Pubmed

GP2/THP gene family of self-binding, GPI-anchored proteins forms a cluster at chromosome 7F1 region in mouse genome.

UMOD GP2

1.09e-07212215325280
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS12 ADAMTS20

7.19e-061212225770910
Pubmed

Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing.

DLK2 PLXNB3

2.07e-052012231291246
Pubmed

A Novel Interacting Protein SERP1 Regulates the N-Linked Glycosylation and Function of GLP-1 Receptor in the Liver.

RNF5 ASGR2

6.45e-053512228597972
Pubmed

New loci associated with kidney function and chronic kidney disease.

UMOD GP2

2.31e-046612220383146
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS12 ADAMTS20

2.99e-047512220637190
InteractionGLP1R interactions

RNF5 ASGR2 GP2

4.69e-05123123int:GLP1R
CytobandEnsembl 112 genes in cytogenetic band chr16p12

UMOD GP2

8.99e-04172122chr16p12
CytobandEnsembl 112 genes in cytogenetic band chr6p21

RNF5 DLK2

7.35e-03503122chr6p21
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS12 ADAMTS20

2.92e-05198250
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 UMOD DMBT1 GP2

7.65e-08161124b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 UMOD DMBT1 GP2

7.65e-08161124f7a89c481f789f624102857be722c95fbeb47595
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 DMBT1 GP2

1.04e-05165123622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD DMBT1 GP2

1.24e-051751237329ebb135fc4311ee9595729b62a5d152c9de8c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD DMBT1 GP2

1.26e-0517612312bccbd56742fcfe19749da802ea1cf62ec9a872
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD DMBT1 GP2

1.35e-0518012372310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UMOD DMBT1 GP2

1.64e-05192123d6ea34391c3f730684b82e912d9cf55e928b3311
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

1.56e-047012226178ee967d647224d93c7a6380f2d15d8fcfb8f
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

1.56e-04701225720505ef03d65c73028616c808420e282823bde
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

2.75e-0493122613c827a643a7b6d70ef932cfa1762e90bc5a338
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

2.75e-0493122d102a0a015a2866e3fe549ac8796b9a0d5923d7e
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

2.75e-04931220967a93dcc72d2d8f12d56de186ec1af55c36001
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

2.75e-04931221a112bd4e5e63826efad0338ce99d7a7ad9c72b9
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

2.75e-04931229c566fc2a8c7630bea28e8e46df55454aa409bc1
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLXNB3 GP2

2.87e-04951220ac6cba7e0ed6083f777287f39a871461fa1bca4
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

2.99e-049712216947da747504c2edb9f2e7ee6f05babda0fae60
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 PLA2G5

3.37e-0410312239d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADAMTS12 PLA2G5

3.37e-0410312201a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

3.57e-041061223aa55c3db4e4abd39c8f2f89f2516927d94ad9d7
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

3.57e-04106122c890c838785dfeda30f3b563194da9cfb49b157a
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

ADAMTS12 UMOD

3.85e-04110122ea90bbf255dccd800293d932c436f41808677bb7
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

4.06e-04113122d5f183263cec9922d23cfd38ce9157eef4e58edb
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

4.06e-041131221df80af2c690dac6bfd3dfd7d0052b66c1ae6ea5
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

4.06e-041131224b5f545dc02364c5d96a02b0acd68faf1ec4192b
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

4.06e-04113122177414e4c859b047a4644664c596a3c22199cdf2
ToppCellHippocampus-Hematopoietic-MACROPHAGE|Hippocampus / BrainAtlas - Mouse McCarroll V32

ASGR2 TLR9

4.06e-04113122927d1071f0719b778f0c3d358c5f96a6ffac6645
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMBT1 TARBP1

4.13e-04114122b350140b389f8762c77a37df473081e1127a8972
ToppCellTCGA-Lung-Recurrent_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

UMOD TLR9

4.28e-0411612278f58c4f4d1c8b72a8111796d8fe5d7a9dfed2b0
ToppCellTCGA-Lung-Recurrent_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype|TCGA-Lung / Sample_Type by Project: Shred V9

UMOD TLR9

4.28e-04116122f1543e140ab2f88dc49e720b80fbcda123785968
ToppCellTCGA-Lung-Recurrent_Tumor-Lung_Carcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

UMOD TLR9

4.28e-04116122dcb56d765ad7531a6cd10a62df3d135a231cacb3
ToppCellTCGA-Lung-Recurrent_Tumor|TCGA-Lung / Sample_Type by Project: Shred V9

UMOD TLR9

4.28e-04116122d9eb0e443899582be06a4f65a1fe46f54adc780e
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PLXNB3 GP2

4.35e-0411712213f068cc4b4a8e9c66bf0e9e5acf9613654bf3f4
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ADAMTS12 ADAMTS20

4.50e-04119122d8fbea9ded96fcc3ebdfb4d28873c563427ce811
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Desmoid_Tumor-7|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ADAMTS12 ADAMTS20

4.50e-041191229e38f13bf98b9ee44b178300e6f80fd08a006296
ToppCellCerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

DLK2 PLXNB3

4.81e-04123122e0eb95f1da12687230b47f0a7367b6138bc7ff1a
ToppCellCerebellum-Macroglia-POLYDENDROCYTE-P1|Cerebellum / BrainAtlas - Mouse McCarroll V32

DLK2 PLXNB3

4.81e-04123122356e2b1b47fdfc2bb2fcd45e44b452fe811f0fd8
ToppCellCerebellum-Macroglia-POLYDENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

DLK2 PLXNB3

4.81e-0412312215f951b4eb2f39888e51e1af18c329953d253f7f
ToppCellCerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

DLK2 PLXNB3

4.81e-04123122b06a38d1081b4485b519853d8c9a2cddfb1e9e75
ToppCellCerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)|Cerebellum / BrainAtlas - Mouse McCarroll V32

DLK2 PLXNB3

4.81e-04123122f60c1dd89da0e204f73772fe0c319eeca82e7e8a
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2_progenitor|E18.5-samps / Age Group, Lineage, Cell class and subclass

PLA2G5 TARBP1

4.96e-04125122b5fed0e0295aa8ad323c318b59bf23cde3e758c8
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADAMTS12 PLA2G5

5.04e-041261226d5075d659dac7b96e6857f8485a7d2c4105d685
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADAMTS12 PLA2G5

5.04e-0412612283f3540683b3b175b10af059ab8898c46eaccc13
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADAMTS12 PLA2G5

5.04e-04126122fd0001a0f3a0a4421f96fd21813c21cf6f01d40e
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADAMTS12 PLA2G5

5.04e-04126122f20424f9baf3c4059cd6b701761e7595400fc47c
ToppCell-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ADAMTS12 TLR9

5.20e-04128122dab10774bc0532a1664fd8ac2b54cffab01be55a
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

5.61e-0413312291e4556658e49f92946d48b194df64c5fc5758fe
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PLXNB3 GP2

5.95e-0413712280f1a6cfb48ccfba1c3545fdcd5fcb3157272aca
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-2|TCGA-Thymus / Sample_Type by Project: Shred V9

RNF5 DLK2

6.13e-041391224747adc5578d2b2371a8593e33f8fc98379aed43
ToppCellControl-Myeloid-Dendritic_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLA2G5 TLR9

6.48e-04143122bb8d4c335682d1a6798bed0de8bb0603054a4944
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLA2G5 TLR9

6.67e-04145122bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ASGR2 PLXNB3

6.76e-04146122a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

ASGR2 PLA2G5

6.76e-041461228b2d104fdb0fdb09410450c6c651e1edb00cae44
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASGR2 TLR9

6.94e-041481227c7c87b57aa16f8b91698489df39ace5a3a53df8
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DMBT1 GP2

7.32e-041521225ce8920aedd39a4daf7082153b5e213707c14227
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

7.42e-0415312239ac25c48e73538f1c10f37bea386e0e88d3e8d0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UMOD GP2

7.42e-041531220307f10e772021ae68a42690634df458672a6df9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_B_(ET)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASGR2 GP2

7.42e-04153122a447ba7cbadfcdb01fcec47e39134c2d836a5535
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_B_(ET)-Glut_ET_L5_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASGR2 GP2

7.42e-04153122f5cbbced865d5c878f8d611ed15866511e85799b
ToppCellGoblet|World / Class top

DMBT1 GP2

7.80e-04157122b352aa37d662629db6a9c6def9ee6d7c49a9071c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_B_(ET)-Glut_ET_L5_FEZF2-Exc_L5_FEZF2_SCN7A|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASGR2 GP2

7.90e-0415812238ff9da2b05235ff8d7812d1ebace9acdf15423d
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

7.90e-04158122e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

7.90e-0415812212661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

7.90e-041581220792c39e6fc0745095af7812de2d50949540d60f
ToppCellGoblet-gob-1|World / Class top

DMBT1 GP2

8.00e-0415912262d4ca2b538382419252e306d7a789b64420fb18
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UMOD GP2

8.00e-04159122c186bf05c61fac348cf41973827cced83fafd58a
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR9 DMBT1

8.00e-04159122f0611a7bf15e2f7dfe828dd247650a30b3d6d44d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UMOD GP2

8.10e-0416012203b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UMOD GP2

8.20e-041611224bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCellTCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue|TCGA-Kidney / Sample_Type by Project: Shred V9

UMOD GP2

8.31e-04162122a0367e9af78e4699b9d89d3e0597589e644f844c
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

8.31e-04162122922ecea81063095b8dd9ac9f9792bf551edbb848
ToppCellTCGA-Kidney-Solid_Tissue_Normal|TCGA-Kidney / Sample_Type by Project: Shred V9

UMOD GP2

8.31e-0416212265549ffdbfe8619693345db78e6ddbdde7b742c9
ToppCellTCGA-Kidney-Solid_Tissue_Normal-Kidney|TCGA-Kidney / Sample_Type by Project: Shred V9

UMOD GP2

8.31e-04162122d007ec42d6458431f6c490df61de7a9caef857f0
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR9 DMBT1

8.41e-041631228509b87748ec460992ae6cedbb155e1c6f6e2e48
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UMOD GP2

8.41e-04163122cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR9 DMBT1

8.41e-04163122e04de78a52cc886623689a913f7852200a77605b
ToppCelldroplet-Pancreas-Exocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

8.61e-04165122c17e00ec9dbe30fcded65a461231dbb13665ddac
ToppCellClub-club-12|World / Class top

DMBT1 GP2

8.61e-041651229b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

8.72e-04166122b7f303203068b205f382788815df487a0ea148ed
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PLA2G5 TLR9

8.72e-041661229fa90d9d484563d44738bb2c6eb0775dffc4d549
ToppCellClub-club-2|World / Class top

ADAMTS12 DMBT1

8.72e-0416612256f11efb6b686b3ee2c34a051f626e3d761b5112
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS12 DMBT1

8.82e-041671223c06894fc6177f3c204094719904da42f08b9af8
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMBT1 GP2

8.82e-041671227cb5b52aaa5b595fe2e97d9e175294ea8d63b165
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASGR2 TLR9

9.14e-041701226ec0cf055ae55e9fac147f7989c47f83ab07270c
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASGR2 TARBP1

9.24e-04171122a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

TLR9 DMBT1

9.24e-04171122f28684ea0e74a22f4c140658496068e28a6d3605
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

TLR9 TARBP1

9.24e-04171122779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

TLR9 TARBP1

9.24e-04171122debbb071d260639b16269c94d172766908325c58
ToppCellClub-club-3|World / Class top

TLR9 DMBT1

9.35e-0417212234fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXNB3 ADAMTS20

9.35e-041721228d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMBT1 GP2

9.46e-04173122b75353fcbc9f8cdb21d4f10ddbc93a83fd797a3c
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

9.46e-04173122f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

9.46e-04173122c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

9.57e-04174122165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

9.57e-041741224289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS20 PLA2G5

9.68e-04175122f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 GP2

9.68e-041751223f1b2e23fec953148fb0711e523c463adb07dca4
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS20 PLA2G5

9.68e-041751227bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UMOD GP2

9.68e-04175122e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS12 PLA2G5

9.68e-04175122b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMBT1 GP2

9.68e-041751220431897d7fcc9cefb516cd36987cf18b7f19a26a
DrugPam(3)CSK(4) peptide

PLA2G5 TLR9

7.59e-0525122ctd:C508075
DrugOleandomycin phosphate [7060-74-4]; Up 200; 5uM; PC3; HG-U133A

ADAMTS12 DLK2 TARBP1

1.27e-041941231935_UP
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; PC3; HT_HG-U133A

DLK2 DMBT1 GP2

1.27e-041941233785_UP
DrugBambuterol hydrochloride [81732-46-9]; Up 200; 10uM; MCF7; HT_HG-U133A

DLK2 PLA2G5 GP2

1.29e-041951233199_UP
DrugTheobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A

DLK2 DMBT1 GP2

1.31e-041961234958_UP
Drugamitriptyline hydrochloride; Down 200; 1uM; MCF7; HG-U133A

DLK2 GP2 TARBP1

1.31e-04196123167_DN
DrugVerteporfin [129497-78-5]; Up 200; 2.8uM; HL60; HT_HG-U133A

ADAMTS12 DLK2 DMBT1

1.31e-041961236133_UP
DrugBenperidol [2062-84-2]; Up 200; 10.4uM; PC3; HT_HG-U133A

ASGR2 DMBT1 GP2

1.35e-041981234196_UP
DrugTropicamide [1508-75-4]; Up 200; 14uM; PC3; HT_HG-U133A

ASGR2 DLK2 DMBT1

1.35e-041981233722_UP
DrugDienestrol [84-17-3]; Up 200; 15uM; PC3; HT_HG-U133A

PLA2G5 DMBT1 GP2

1.35e-041981235727_UP
DrugVincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A

ASGR2 DLK2 PLA2G5

1.35e-041981233976_UP
DrugTrolox [53188-07-1]; Up 200; 16uM; HL60; HG-U133A

ADAMTS12 DLK2 GP2

1.37e-041991231734_UP
DrugTropine [120-29-6]; Up 200; 28.4uM; PC3; HT_HG-U133A

PLA2G5 DMBT1 GP2

1.37e-041991235790_UP
DrugDorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; PC3; HT_HG-U133A

ADAMTS12 PLA2G5 DMBT1

1.37e-041991235785_UP
DrugAconitine [302-27-2]; Up 200; 6.2uM; HL60; HG-U133A

PLA2G5 DMBT1 GP2

1.37e-041991231784_UP
DrugIsometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A

DLK2 DMBT1 GP2

1.39e-042001235502_UP
Drugtegafur

ADAMTS12 ADAMTS20

2.95e-0449122CID000005386
Diseaseuromodulin measurement

ASGR2 UMOD

4.90e-0526122EFO_0021778
Diseaseobesity (implicated_via_orthology)

PLXNB3 ADAMTS20

3.32e-03215122DOID:9970 (implicated_via_orthology)
Diseasetype 1 diabetes mellitus

UMOD GP2

4.19e-03242122MONDO_0005147
Diseasebone density

DMBT1 TARBP1

1.04e-02388122EFO_0003923
Diseasecystatin C measurement

DLK2 UMOD

1.12e-02402122EFO_0004617
Diseasesevere acute respiratory syndrome, COVID-19

ADAMTS12 PLA2G5

1.37e-02447122EFO_0000694, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
CCPVNWVEHQGSCYW

ASGR2

176

P07307
SCNEHLCCHWATGNW

ADAMTS12

1466

P58397
CHGNCVFTRWHYSEW

ADAMTS20

961

P59510
WRCHWCPQSSHCVYG

PLXNB3

641

Q9ULL4
TACAHWSGNCCFWKT

GP2

136

P55259
DWCCWAHDHCYGRLE

PLA2G5

61

P39877
CHQPWQCICHSGWAG

DLK2

71

Q6UY11
WSCPHNGWLTHNCGH

DMBT1

311

Q9UGM3
WSCPHNGWLSHNCGH

DMBT1

571

Q9UGM3
WSCPHNGWLSHNCGH

DMBT1

1586

Q9UGM3
VCGHLYCWPCLHQWL

RNF5

41

Q99942
KACAHWSGHCCLWDA

UMOD

246

P07911
HHLCGWDLWYCFHLC

TLR9

836

Q9NR96
NGCWLFHPSWHMCIY

TARBP1

366

Q13395