Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR5P3 GPR173 OR2W1 OR5K3 OPN1SW F2RL2 GRPR OR6M1 OR8G1 OR9A1P OR10G6 TAS2R3 TAS2R1 ACKR3 AGTR2 HRH4 OR4B1 OR51G1 GPR132 OR51B2 HCRTR1 HRH3	6.84e-07	884	149	22	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	NPC1 OR5P3 ITGA11 GPR173 OR2W1 OR5K3 PTPRU OPN1SW F2RL2 GRPR OR6M1 OR8G1 OR9A1P OR10G6 TAS2R3 TAS2R1 ACKR3 AGTR2 HRH4 OR4B1 OR51G1 IL1R1 IL1RAP GPR132 OR51B2 HCRTR1 HRH3	2.41e-06	1353	149	27	GO:0004888
GeneOntologyMolecularFunction	histone H2AX kinase activity	ATR BAZ1B ATM	4.03e-06	5	149	3	GO:0141003
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	5.53e-05	2	149	2	GO:0120300
GeneOntologyMolecularFunction	aspartate:glutamate, proton antiporter activity	SLC25A12 SLC25A13	5.53e-05	2	149	2	GO:0000515
GeneOntologyMolecularFunction	3-sulfino-L-alanine: proton, glutamate antiporter activity	SLC25A12 SLC25A13	5.53e-05	2	149	2	GO:0000514
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	5.53e-05	2	149	2	GO:0044017
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-CH group of donors	PTGES2 DHCR7 AKR1C3 DECR2 SDHB	9.94e-05	62	149	5	GO:0016627
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	PTGES2 DHCR7 AKR1C3 DECR2	1.16e-04	34	149	4	GO:0016628
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	1.65e-04	3	149	2	GO:0043993
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	ATR ATM	1.65e-04	3	149	2	GO:0035979
GeneOntologyMolecularFunction	steroid dehydrogenase activity	RDH8 AKR1C3 HSD17B11 HSDL1	2.00e-04	39	149	4	GO:0016229
GeneOntologyMolecularFunction	guanine transmembrane transporter activity	SLC43A3 SLC29A2	3.29e-04	4	149	2	GO:0015208
GeneOntologyMolecularFunction	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	RDH8 AKR1C3 HSD17B11	4.23e-04	20	149	3	GO:0004303
GeneOntologyMolecularFunction	adenine transmembrane transporter activity	SLC43A3 SLC29A2	5.45e-04	5	149	2	GO:0015207
GeneOntologyMolecularFunction	glycolipid mannosyltransferase activity	PIGB ALG2	5.45e-04	5	149	2	GO:0004376
GeneOntologyMolecularFunction	amino acid:monoatomic cation antiporter activity	SLC25A12 SLC25A13	5.45e-04	5	149	2	GO:0140848
GeneOntologyMolecularFunction	histamine receptor activity	HRH4 HRH3	8.13e-04	6	149	2	GO:0004969
GeneOntologyMolecularFunction	hexosyltransferase activity	PIGB UGT1A7 UGT1A5 B3GNT3 ALG2 MGAT1 WDFY3	1.05e-03	211	149	7	GO:0016758
GeneOntologyMolecularFunction	G protein-coupled acetylcholine receptor activity	HRH4 HRH3	1.13e-03	7	149	2	GO:0016907
GeneOntologyMolecularFunction	histone kinase activity	ATR BAZ1B ATM	1.16e-03	28	149	3	GO:0035173
GeneOntologyMolecularFunction	glycosyltransferase activity	PIGB UGT1A7 UGT1A5 B3GNT3 ALG2 MGAT1 ST3GAL6 WDFY3	1.47e-03	288	149	8	GO:0016757
GeneOntologyMolecularFunction	interleukin-1 receptor activity	IL1R1 IL1RAP	1.50e-03	8	149	2	GO:0004908
GeneOntologyMolecularFunction	olfactory receptor activity	OR5P3 OR2W1 OR5K3 OR6M1 OR8G1 OR9A1P OR10G6 OR4B1 OR51G1 OR51B2	1.50e-03	431	149	10	GO:0004984
GeneOntologyMolecularFunction	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	RDH8 AKR1C3 HSD17B11	1.89e-03	33	149	3	GO:0033764
GeneOntologyBiologicalProcess	regulation of cellular response to heat	ATR CREBBP ATM EP300	4.69e-06	16	151	4	GO:1900034
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR5P3 GPR173 OR2W1 OR5K3 OPN1SW F2RL2 GRPR OR6M1 OR8G1 OR9A1P OR10G6 TAS2R3 TAS2R1 PIK3CB ACKR3 AGTR2 AKR1C3 HRH4 OR4B1 OR51G1 NOS2 GPR132 OR51B2 HCRTR1 HRH3	2.75e-05	1395	151	25	GO:0007186
GeneOntologyBiologicalProcess	telomerase catalytic core complex assembly	ATR ATM	5.32e-05	2	151	2	GO:1904868
GeneOntologyBiologicalProcess	positive regulation of telomerase catalytic core complex assembly	ATR ATM	5.32e-05	2	151	2	GO:1904884
GeneOntologyBiologicalProcess	regulation of telomerase catalytic core complex assembly	ATR ATM	5.32e-05	2	151	2	GO:1904882
GeneOntologyBiologicalProcess	carboxylic acid metabolic process	NPC1 PTGES2 UGT1A7 UGT1A5 NAIP SHMT1 GPAM CPT1B SLC25A12 SLC25A13 AKR1C3 ELOVL3 DECR2 ACMSD GPT2 NOS2 EP300 FOXK1 SDHB WDTC1	6.90e-05	1035	151	20	GO:0019752
GeneOntologyBiologicalProcess	organophosphate biosynthetic process	PIGB IP6K3 AGPAT4 SHMT1 GPAM CEPT1 SLC25A12 GUCY1B1 PIK3CB SLC25A13 ELOVL3 ATM ACMSD NOS2 SDHB	7.94e-05	644	151	15	GO:0090407
GeneOntologyBiologicalProcess	oxoacid metabolic process	NPC1 PTGES2 UGT1A7 UGT1A5 NAIP SHMT1 GPAM CPT1B SLC25A12 SLC25A13 AKR1C3 ELOVL3 DECR2 ACMSD GPT2 NOS2 EP300 FOXK1 SDHB WDTC1	9.32e-05	1058	151	20	GO:0043436
GeneOntologyBiologicalProcess	organic acid metabolic process	NPC1 PTGES2 UGT1A7 UGT1A5 NAIP SHMT1 GPAM CPT1B SLC25A12 SLC25A13 AKR1C3 ELOVL3 DECR2 ACMSD GPT2 NOS2 EP300 FOXK1 SDHB WDTC1	1.01e-04	1064	151	20	GO:0006082
GeneOntologyBiologicalProcess	tRNA export from nucleus	NOL6 XPOT	1.59e-04	3	151	2	GO:0006409
GeneOntologyBiologicalProcess	establishment of RNA localization to telomere	ATR ATM	1.59e-04	3	151	2	GO:0097694
GeneOntologyBiologicalProcess	establishment of protein-containing complex localization to telomere	ATR ATM	1.59e-04	3	151	2	GO:0097695
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR5P3 OR2W1 OR5K3 OR6M1 OR8G1 OR9A1P OR10G6 TAS2R3 TAS2R1 OR4B1 OR51G1 CFAP69 OR51B2	1.99e-04	547	151	13	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR5P3 OR2W1 OR5K3 OR6M1 OR8G1 OR9A1P OR10G6 TAS2R3 TAS2R1 OR4B1 OR51G1 OR51B2	2.44e-04	485	151	12	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus	OR5P3 PIEZO1 NAIP OR2W1 OR5K3 OPN1SW OR6M1 OR8G1 OR9A1P OR10G6 TAS2R3 TAS2R1 OR4B1 OR51G1 OR51B2	2.76e-04	722	151	15	GO:0051606
GeneOntologyBiologicalProcess	lipid biosynthetic process	RDH8 PTGES2 PIGB IP6K3 AGPAT4 GPAM CEPT1 ST3GAL6 PIK3CB DHCR7 AKR1C3 ELOVL3 DECR2 ATM HSD17B11 WDTC1	3.14e-04	813	151	16	GO:0008610
GeneOntologyBiologicalProcess	guanine transmembrane transport	SLC43A3 SLC29A2	3.16e-04	4	151	2	GO:1903716
GeneOntologyBiologicalProcess	hypoxanthine transport	SLC43A3 SLC29A2	3.16e-04	4	151	2	GO:0035344
GeneOntologyBiologicalProcess	N-terminal peptidyl-lysine acetylation	CREBBP EP300	3.16e-04	4	151	2	GO:0018076
GeneOntologyBiologicalProcess	guanine transport	SLC43A3 SLC29A2	3.16e-04	4	151	2	GO:0015854
HumanPheno	Abnormal forearm bone morphology	ATR DYNC2H1 BAZ1B CREBBP FANCD2 DHCR7 EP300 SLX4 CHST3	4.23e-05	236	38	9	HP:0040072
HumanPheno	Frontal hirsutism	CREBBP SLC25A12 EP300	4.43e-05	10	38	3	HP:0011335
HumanPheno	Pes planus	ATR BAZ1B CREBBP ALG2 SIL1 FANCD2 SLC9A7 EP300 SLX4 VPS13B CHST3	4.53e-05	365	38	11	HP:0001763
HumanPheno	Abnormal forearm morphology	ATR DYNC2H1 BAZ1B CREBBP FANCD2 DHCR7 EP300 SLX4 CHST3	4.68e-05	239	38	9	HP:0002973
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	5.42e-05	2	38	2	HP:0008107
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	5.42e-05	2	38	2	HP:0034227
HumanPheno	High axial triradius	CREBBP EP300	5.42e-05	2	38	2	HP:0001042
HumanPheno	Aplasia/hypoplasia involving forearm bones	ATR DYNC2H1 FANCD2 DHCR7 SLX4 CHST3	8.17e-05	100	38	6	HP:0006503
HumanPheno	Abnormal uterus morphology	DYNC2H1 FANCD2 DHCR7 ATM EP300 SLX4 SDHB	1.36e-04	158	38	7	HP:0031105
HumanPheno	Nasogastric tube feeding in infancy	CREBBP GPT2 EP300 UNC80	1.46e-04	37	38	4	HP:0011470
HumanPheno	Abnormal morphology of the radius	ATR BAZ1B CREBBP FANCD2 DHCR7 EP300 SLX4 CHST3	1.54e-04	217	38	8	HP:0002818
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	1.62e-04	3	38	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	1.62e-04	3	38	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	1.62e-04	3	38	2	HP:0000756
HumanPheno	Humoral immunodeficiency	CREBBP EP300	1.62e-04	3	38	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	1.62e-04	3	38	2	HP:0005322
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP EP300	1.62e-04	3	38	2	HP:0005895
HumanPheno	Preaxial polydactyly	PIGB DYNC2H1 CREBBP FANCD2 EP300 SLX4 TCTN1	1.71e-04	164	38	7	HP:0100258
HumanPheno	Cellular immunodeficiency	CREBBP ATM EP300 SDHB	1.80e-04	39	38	4	HP:0005374
HumanPheno	Abnormal 5th finger morphology	ATR DYNC2H1 BAZ1B CREBBP FANCD2 DHCR7 SLC9A7 EP300 SLX4 TCTN1 VPS13B CHST3	2.07e-04	509	38	12	HP:0004207
HumanPheno	Forearm undergrowth	ATR DYNC2H1 FANCD2 SLX4 CHST3	2.08e-04	75	38	5	HP:0009821
HumanPheno	Abnormal morphology of bones of the upper limbs	ATR DYNC2H1 BAZ1B CREBBP SIL1 FANCD2 DHCR7 EP300 SLX4 VPS13B CHST3	2.28e-04	436	38	11	HP:0040065
HumanPheno	Mitral valve prolapse	VWF BAZ1B CREBBP EP300 VPS13B CHST3	2.57e-04	123	38	6	HP:0001634
HumanPheno	Facial hirsutism	CREBBP SLC25A12 EP300	2.89e-04	18	38	3	HP:0009937
HumanPheno	Trichiasis	CREBBP EP300	3.22e-04	4	38	2	HP:0001128
HumanPheno	Visceral hemangioma	CREBBP EP300	3.22e-04	4	38	2	HP:0410266
HumanPheno	Talon cusp	CREBBP EP300	3.22e-04	4	38	2	HP:0011087
HumanPheno	Widened distal phalanges	CREBBP EP300	3.22e-04	4	38	2	HP:0006200
HumanPheno	Vascular ring	CREBBP EP300	3.22e-04	4	38	2	HP:0010775
HumanPheno	Hepatic hemangioma	CREBBP EP300	3.22e-04	4	38	2	HP:0031207
HumanPheno	Abnormal conjugate eye movement	NPC1 ATR BAZ1B PGM2L1 CREBBP ALG2 HPS3 SIL1 FANCD2 ACKR3 DHCR7 SLC9A7 ATM EP300 SLX4 TCTN1 VPS13B UNC80 CHST3	3.26e-04	1198	38	19	HP:0000549
HumanPheno	Blepharophimosis	ATR BAZ1B CREBBP FANCD2 EP300 SLX4	3.33e-04	129	38	6	HP:0000581
HumanPheno	Abnormal dermatoglyphics	ATR BAZ1B PGM2L1 CREBBP SLC25A12 DHCR7 EP300 VPS13B CHST3	3.80e-04	314	38	9	HP:0007477
HumanPheno	Upper limb undergrowth	ATR DYNC2H1 FANCD2 SLX4 CHST3	3.95e-04	86	38	5	HP:0009824
HumanPheno	Absent earlobe	ATR CREBBP EP300	4.00e-04	20	38	3	HP:0000387
HumanPheno	Lower extremity joint dislocation	ATR BAZ1B CREBBP SIL1 FANCD2 DHCR7 EP300 SLX4 CHST3	4.17e-04	318	38	9	HP:0030311
HumanPheno	Abnormal earlobe morphology	PIGB ATR PGM2L1 CREBBP EP300 VPS13B	4.61e-04	137	38	6	HP:0000363
HumanPheno	Cafe-au-lait spot	CREBBP FANCD2 ATM EP300 SLX4 SDHB	4.61e-04	137	38	6	HP:0000957
HumanPheno	Localized hirsutism	CREBBP SLC25A12 EP300	4.64e-04	21	38	3	HP:0009889
HumanPheno	Slanting of the palpebral fissure	PIGB ATR PGM2L1 CREBBP ALG2 CYFIP2 FANCD2 DHCR7 SLC9A7 EP300 SLX4 VPS13B UNC80 CHST3	5.28e-04	739	38	14	HP:0200006
HumanPheno	Papillary cystadenoma of the epididymis	CREBBP EP300	5.34e-04	5	38	2	HP:0009715
HumanPheno	Supernumerary cusp	CREBBP EP300	5.34e-04	5	38	2	HP:0033777
HumanPheno	Epididymal neoplasm	CREBBP EP300	5.34e-04	5	38	2	HP:0030421
HumanPheno	Abnormal upper limb bone morphology	ATR DYNC2H1 BAZ1B CREBBP SIL1 FANCD2 DHCR7 EP300 SLX4 VPS13B CHST3	5.67e-04	484	38	11	HP:0040070
HumanPheno	Aplasia/Hypoplasia of the earlobes	ATR CREBBP EP300 VPS13B	5.93e-04	53	38	4	HP:0009906
HumanPheno	Abnormal thumb morphology	PIGB DYNC2H1 BAZ1B CREBBP FANCD2 DHCR7 EP300 SLX4 TCTN1 CHST3	5.96e-04	408	38	10	HP:0001172
HumanPheno	Aplasia/hypoplasia involving bones of the upper limbs	PIGB ATR DYNC2H1 CREBBP SIL1 FANCD2 DHCR7 EP300 SLX4 VPS13B UNC80 CHST3	6.16e-04	572	38	12	HP:0006496
HumanPheno	Dislocated radial head	ATR CREBBP EP300 CHST3	6.38e-04	54	38	4	HP:0003083
HumanPheno	Abnormal mitral valve morphology	VWF BAZ1B CREBBP EP300 VPS13B CHST3	6.47e-04	146	38	6	HP:0031477
HumanPheno	Sandal gap	ATR CREBBP EP300 VPS13B CHST3	6.57e-04	96	38	5	HP:0001852
HumanPheno	Hypoplasia of the ulna	DYNC2H1 FANCD2 SLX4 CHST3	6.84e-04	55	38	4	HP:0003022
HumanPheno	Strabismus	ATR BAZ1B PGM2L1 CREBBP ALG2 HPS3 SIL1 FANCD2 ACKR3 DHCR7 SLC9A7 ATM EP300 SLX4 TCTN1 VPS13B UNC80 CHST3	6.97e-04	1159	38	18	HP:0000486
HumanPheno	Downslanted palpebral fissures	ATR PGM2L1 CREBBP ALG2 CYFIP2 DHCR7 SLC9A7 EP300 VPS13B UNC80 CHST3	7.11e-04	497	38	11	HP:0000494
HumanPheno	Abnormal morphology of bones of the lower limbs	ATR DYNC2H1 CREBBP PLEKHM1 SIL1 FANCD2 EP300 SLX4 VPS13B CHST3	7.78e-04	422	38	10	HP:0040066
HumanPheno	Abnormality of the radial head	ATR CREBBP EP300 CHST3	7.84e-04	57	38	4	HP:0003995
HumanPheno	Prominent antitragus	PGM2L1 CHST3	7.98e-04	6	38	2	HP:0008593
HumanPheno	Large foramen magnum	CREBBP EP300	7.98e-04	6	38	2	HP:0002700
HumanPheno	Short long bone	ATR DYNC2H1 SIL1 FANCD2 EP300 SLX4 VPS13B CHST3	8.29e-04	278	38	8	HP:0003026
HumanPheno	Phonophobia	BAZ1B CREBBP EP300	8.85e-04	26	38	3	HP:0002183
HumanPheno	Aplasia/Hypoplasia of the ulna	DYNC2H1 FANCD2 SLX4 CHST3	9.52e-04	60	38	4	HP:0006495
HumanPheno	Abnormality of the palpebral fissures	PIGB ATR BAZ1B PGM2L1 CREBBP ALG2 CYFIP2 FANCD2 DHCR7 SLC9A7 EP300 SLX4 VPS13B UNC80 CHST3	9.65e-04	880	38	15	HP:0008050
HumanPheno	Broad distal phalanx of finger	CREBBP EP300 CHST3	9.90e-04	27	38	3	HP:0009836
HumanPheno	Abnormal incisor morphology	ATR CREBBP EP300 VPS13B	1.08e-03	62	38	4	HP:0011063
HumanPheno	Abnormality of the humeroradial joint	ATR CREBBP EP300 CHST3	1.08e-03	62	38	4	HP:0100744
HumanPheno	Deviated nasal septum	CREBBP EP300	1.11e-03	7	38	2	HP:0004411
HumanPheno	Epicanthus	DYNC2H1 PIEZO1 BAZ1B PGM2L1 CREBBP ALG2 FANCD2 DHCR7 GPT2 EP300 SLX4 UNC80	1.17e-03	614	38	12	HP:0000286
HumanPheno	Multiple cafe-au-lait spots	FANCD2 ATM SLX4 SDHB	1.21e-03	64	38	4	HP:0007565
HumanPheno	Prominent nose	ATR PGM2L1 CREBBP EP300 UNC80	1.22e-03	110	38	5	HP:0000448
Domain	GPCR_Rhodpsn	OR5P3 GPR173 OR2W1 OR5K3 OR3A4P OPN1SW F2RL2 GRPR OR6M1 OR8G1 OR10G6 TAS2R3 ACKR3 AGTR2 HRH4 OR4B1 OR51G1 GPR132 OR51B2 HCRTR1 HRH3	1.64e-07	692	150	21	IPR000276
Domain	7tm_1	OR5P3 GPR173 OR2W1 OR5K3 OR3A4P OPN1SW F2RL2 GRPR OR6M1 OR8G1 OR10G6 ACKR3 AGTR2 HRH4 OR4B1 OR51G1 GPR132 OR51B2 HCRTR1 HRH3	5.08e-07	677	150	20	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR5P3 GPR173 OR2W1 OR5K3 OR3A4P OPN1SW F2RL2 GRPR OR6M1 OR8G1 OR10G6 ACKR3 AGTR2 HRH4 OR4B1 OR51G1 GPR132 OR51B2 HCRTR1 HRH3	6.11e-07	685	150	20	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR5P3 GPR173 OR2W1 OR5K3 OR3A4P OPN1SW F2RL2 GRPR OR6M1 OR8G1 OR10G6 ACKR3 AGTR2 HRH4 OR4B1 OR51G1 GPR132 OR51B2 HCRTR1 HRH3	7.00e-07	691	150	20	PS50262
Domain	GPCR_Rhodpsn_7TM	OR5P3 GPR173 OR2W1 OR5K3 OPN1SW F2RL2 GRPR OR6M1 OR8G1 ACKR3 AGTR2 HRH4 OR4B1 OR51G1 GPR132 OR51B2 HCRTR1 HRH3	7.40e-06	670	150	18	IPR017452
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	6.41e-05	2	150	2	IPR014744
Domain	ZnF_TAZ	CREBBP EP300	6.41e-05	2	150	2	SM00551
Domain	-	CREBBP EP300	6.41e-05	2	150	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	6.41e-05	2	150	2	IPR010303
Domain	-	CREBBP EP300	6.41e-05	2	150	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	6.41e-05	2	150	2	PF09030
Domain	zf-TAZ	CREBBP EP300	6.41e-05	2	150	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	6.41e-05	2	150	2	PS50134
Domain	KAT11	CREBBP EP300	6.41e-05	2	150	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	6.41e-05	2	150	2	IPR000197
Domain	KIX	CREBBP EP300	6.41e-05	2	150	2	PF02172
Domain	HAT_KAT11	CREBBP EP300	6.41e-05	2	150	2	PF08214
Domain	KIX	CREBBP EP300	6.41e-05	2	150	2	PS50952
Domain	CBP_P300_HAT	CREBBP EP300	6.41e-05	2	150	2	IPR031162
Domain	DUF902	CREBBP EP300	6.41e-05	2	150	2	PF06001
Domain	-	CREBBP EP300	6.41e-05	2	150	2	1.10.246.20
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	6.41e-05	2	150	2	IPR013178
Domain	KIX_dom	CREBBP EP300	6.41e-05	2	150	2	IPR003101
Domain	CBP_P300_HAT	CREBBP EP300	6.41e-05	2	150	2	PS51727
Domain	ARM-type_fold	USP34 ZYG11A ATR SIL1 PIK3CB ATM WDFY3 CFAP69 GCN1 TARBP1 XPOT	9.46e-05	339	150	11	IPR016024
Domain	ZnF_TTF	ZNF862 ZMYM1	1.91e-04	3	150	2	SM00597
Domain	Znf_TTF	ZNF862 ZMYM1	1.91e-04	3	150	2	IPR006580
Domain	PI3/4_kinase_CS	ATR PIK3CB ATM	2.15e-04	15	150	3	IPR018936
Domain	-	ATR PIK3CB ATM	2.63e-04	16	150	3	1.10.1070.11
Domain	PI3Kc	ATR PIK3CB ATM	2.63e-04	16	150	3	SM00146
Domain	PI3_PI4_kinase	ATR PIK3CB ATM	3.79e-04	18	150	3	PF00454
Domain	PI3_4_KINASE_1	ATR PIK3CB ATM	3.79e-04	18	150	3	PS00915
Domain	PI3_4_KINASE_2	ATR PIK3CB ATM	3.79e-04	18	150	3	PS00916
Domain	PI3/4_kinase_cat_dom	ATR PIK3CB ATM	3.79e-04	18	150	3	IPR000403
Domain	PI3_4_KINASE_3	ATR PIK3CB ATM	3.79e-04	18	150	3	PS50290
Domain	FATC	ATR ATM	6.31e-04	5	150	2	PF02260
Domain	ADH_SHORT	RDH8 DECR2 HSD17B11 HSDL1	8.62e-04	53	150	4	PS00061
Domain	Nuc_rcpt_coact	CREBBP EP300	9.41e-04	6	150	2	IPR009110
Domain	IL-1_rcpt_I/II-typ	IL1R1 IL1RAP	9.41e-04	6	150	2	IPR004074
Domain	FAT	ATR ATM	9.41e-04	6	150	2	PS51189
Domain	FATC	ATR ATM	9.41e-04	6	150	2	PS51190
Domain	FAT	ATR ATM	9.41e-04	6	150	2	PF02259
Domain	PIK-rel_kinase_FAT	ATR ATM	9.41e-04	6	150	2	IPR003151
Domain	FATC_dom	ATR ATM	9.41e-04	6	150	2	IPR003152
Domain	PIK_FAT	ATR ATM	9.41e-04	6	150	2	IPR014009
Domain	FATC	ATR ATM	9.41e-04	6	150	2	SM01343
Domain	adh_short	RDH8 DECR2 HSD17B11 HSDL1	9.92e-04	55	150	4	PF00106
Domain	SDR_fam	RDH8 DECR2 HSD17B11 HSDL1	1.06e-03	56	150	4	IPR002347
Domain	Bromodomain_CS	BAZ1B CREBBP EP300	1.15e-03	26	150	3	IPR018359
Domain	Olfact_rcpt	OR5P3 OR2W1 OR5K3 OR3A4P OR6M1 OR8G1 OR10G6 OR4B1 OR51G1 OR51B2	1.31e-03	393	150	10	IPR000725
Domain	ARM-like	ZYG11A ATR SIL1 WDFY3 CFAP69 GCN1 TARBP1 XPOT	1.55e-03	270	150	8	IPR011989
Domain	HATC_C_dom	ZNF862 ZMYM1	1.74e-03	8	150	2	IPR008906
Domain	Dimer_Tnp_hAT	ZNF862 ZMYM1	1.74e-03	8	150	2	PF05699
Domain	-	ZYG11A ATR SIL1 WDFY3 CFAP69 GCN1 XPOT	2.14e-03	222	150	7	1.25.10.10
Domain	BROMODOMAIN_1	BAZ1B CREBBP EP300	3.23e-03	37	150	3	PS00633
Domain	IL-1_rcpt_fam	IL1R1 IL1RAP	3.36e-03	11	150	2	IPR015621
Domain	Bromodomain	BAZ1B CREBBP EP300	3.49e-03	38	150	3	PF00439
Domain	BROMODOMAIN_2	BAZ1B CREBBP EP300	4.33e-03	41	150	3	PS50014
Domain	Bromodomain	BAZ1B CREBBP EP300	4.63e-03	42	150	3	IPR001487
Domain	BROMO	BAZ1B CREBBP EP300	4.63e-03	42	150	3	SM00297
Domain	-	BAZ1B CREBBP EP300	4.63e-03	42	150	3	1.20.920.10
Domain	Acyltransferase	AGPAT4 GPAM	7.14e-03	16	150	2	PF01553
Pubmed	p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint.	ATR CREBBP EP300	8.51e-08	3	154	3	17272271
Pubmed	CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity.	NUP98 CREBBP EP300	8.51e-08	3	154	3	9858599
Pubmed	Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance.	ATR FANCD2 ATM	8.51e-08	3	154	3	16943440
Pubmed	FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.	ATR FANCD2 ATM	3.39e-07	4	154	3	18931676
Pubmed	DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM.	ATR CREBBP ATM	8.46e-07	5	154	3	16293623
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 TUT7 NOL6 NUP98 BAZ1B DDX56 UTP18 FAM120A MYH14 SLC25A13 ATM GCN1 USP47 XPOT	1.39e-06	653	154	14	22586326
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NPC1 USP34 PTGES2 RAP1GAP VWF CREBBP FBXL16 FAM120A GUCY1B1 MYH14 AKR1C3 ATM WDFY3 CABIN1 TARBP1 EP300 SLX4 USP47 XPOT	4.46e-06	1285	154	19	35914814
Pubmed	DNA damage repair machinery and HIV escape from innate immune sensing.	ATR ATM SLX4	4.69e-06	8	154	3	24795708
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	PTGES2 FANCD2 CEPT1 SLC25A12 SLC25A13 GCN1 IQGAP3 XPOT	4.91e-06	211	154	8	17314511
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ATR DYNC2H1 MRPL37 NOL6 NUP98 BAZ1B DDX56 CYFIP2 FANCD2 UTP18 FAM120A MYH14 DHCR7 SLC25A13 ATM GCN1 IQGAP3 SDHB XPOT NPAS2	5.32e-06	1425	154	20	30948266
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	DYNC2H1 MRPL37 NOL6 LRRC70 CREBBP EHBP1L1 MRPS24 SUPT7L WDFY3 TARBP1 EP300 CDH17 USP47	5.82e-06	638	154	13	31182584
Pubmed	HIV-1 chromatin, transcription, and the regulatory protein Tat.	NELFCD CREBBP EP300	7.01e-06	9	154	3	24158816
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NPC1 USP34 PIEZO1 DDX56 SLC29A2 PLEKHM1 SIL1 EHBP1L1 MGAT1 SH3TC1 ADAMTS7 WDFY3 CABIN1 GCN1 IQGAP3 EP300 FOXK1	8.84e-06	1105	154	17	35748872
Pubmed	A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.	USP34 ATR ATM	9.99e-06	10	154	3	17478428
Pubmed	The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.	ATR CREBBP EP300	9.99e-06	10	154	3	20347598
Pubmed	Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.	PTGES2 ATR FANCD2 ATM IL1R1 NOS2 EP300	1.14e-05	170	154	7	19064572
Pubmed	Activator-Mediator binding regulates Mediator-cofactor interactions.	ATM GCN1 EP300	1.37e-05	11	154	3	20534441
Pubmed	The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins.	BAZ1B FANCD2 ATM	1.37e-05	11	154	3	24800743
Pubmed	Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.	CREBBP EP300 NPAS2	1.82e-05	12	154	3	14645221
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	1.95e-05	2	154	2	27881875
Pubmed	Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks.	ATR ATM	1.95e-05	2	154	2	19285939
Pubmed	Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment.	FANCD2 SLX4	1.95e-05	2	154	2	27624129
Pubmed	Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.	SLC25A12 SLC25A13	1.95e-05	2	154	2	25410934
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	1.95e-05	2	154	2	34845315
Pubmed	Expression variations of DNA damage response genes ATM and ATR in blood cancer patients.	ATR ATM	1.95e-05	2	154	2	37338595
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	1.95e-05	2	154	2	19729597
Pubmed	DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes.	ATR ATM	1.95e-05	2	154	2	28851706
Pubmed	Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM).	ATR ATM	1.95e-05	2	154	2	34151669
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	1.95e-05	2	154	2	39287984
Pubmed	Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.	ATR ATM	1.95e-05	2	154	2	16213462
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	1.95e-05	2	154	2	20717166
Pubmed	ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.	ATR ATM	1.95e-05	2	154	2	27442013
Pubmed	Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells.	ATR ATM	1.95e-05	2	154	2	24726882
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	1.95e-05	2	154	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	1.95e-05	2	154	2	11559821
Pubmed	rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis.	ATR ATM	1.95e-05	2	154	2	26061708
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	1.95e-05	2	154	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	1.95e-05	2	154	2	19822209
Pubmed	Voltage sensitivities and deactivation kinetics of histamine H₃ and H₄ receptors.	HRH4 HRH3	1.95e-05	2	154	2	22885137
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	1.95e-05	2	154	2	24522976
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	1.95e-05	2	154	2	21847097
Pubmed	Functional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript.	ATR ATM	1.95e-05	2	154	2	20103595
Pubmed	Sodium binding to hH3R and hH 4R--a molecular modeling study.	HRH4 HRH3	1.95e-05	2	154	2	25098339
Pubmed	Interplay between ATM and ATR in the regulation of common fragile site stability.	ATR ATM	1.95e-05	2	154	2	17934520
Pubmed	Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.	ATR ATM	1.95e-05	2	154	2	25483091
Pubmed	ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.	ATR ATM	1.95e-05	2	154	2	23592994
Pubmed	Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex.	IL1R1 IL1RAP	1.95e-05	2	154	2	7775431
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	1.95e-05	2	154	2	34813504
Pubmed	Propolypeptide of von Willebrand factor is a novel ligand for very late antigen-4 integrin.	VWF ITGA4	1.95e-05	2	154	2	9079671
Pubmed	Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway.	ATR ATM	1.95e-05	2	154	2	19527713
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	1.95e-05	2	154	2	20301699
Pubmed	ATM-ROS-iNOS axis regulates nitric oxide mediated cellular senescence.	ATM NOS2	1.95e-05	2	154	2	27845209
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	1.95e-05	2	154	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	1.95e-05	2	154	2	37816914
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	1.95e-05	2	154	2	11438528
Pubmed	Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.	CREBBP EP300	1.95e-05	2	154	2	10918613
Pubmed	ATM and ATR signaling at a glance.	ATR ATM	1.95e-05	2	154	2	26567218
Pubmed	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.	CREBBP EP300	1.95e-05	2	154	2	35502657
Pubmed	p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.	CREBBP EP300	1.95e-05	2	154	2	31898871
Pubmed	Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.	NPC1 RMC1	1.95e-05	2	154	2	9211850
Pubmed	Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.	CREBBP EP300	1.95e-05	2	154	2	30888860
Pubmed	Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.	CREBBP EP300	1.95e-05	2	154	2	27881443
Pubmed	Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.	CREBBP EP300	1.95e-05	2	154	2	19272189
Pubmed	Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.	CREBBP EP300	1.95e-05	2	154	2	32690000
Pubmed	CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.	CREBBP EP300	1.95e-05	2	154	2	30953353
Pubmed	Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.	CREBBP EP300	1.95e-05	2	154	2	21803292
Pubmed	Cancer genome datamining and functional genetic analysis implicate mechanisms of ATM/ATR dysfunction underpinning carcinogenesis.	ATR ATM	1.95e-05	2	154	2	33742106
Pubmed	HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.	CREBBP EP300	1.95e-05	2	154	2	9811832
Pubmed	Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.	CREBBP EP300	1.95e-05	2	154	2	24089570
Pubmed	Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle.	SLC25A12 SLC25A13	1.95e-05	2	154	2	17213189
Pubmed	Roles of ATM and ATR in DNA double strand breaks and replication stress.	ATR ATM	1.95e-05	2	154	2	33887296
Pubmed	Evolutionarily conserved human targets of adenosine to inosine RNA editing.	CYFIP2 BLCAP	1.95e-05	2	154	2	15731336
Pubmed	ATR disruption leads to chromosomal fragmentation and early embryonic lethality.	ATR ATM	1.95e-05	2	154	2	10691732
Pubmed	Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.	CREBBP EP300	1.95e-05	2	154	2	15706485
Pubmed	AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.	CREBBP EP300	1.95e-05	2	154	2	39266679
Pubmed	A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.	CREBBP EP300	1.95e-05	2	154	2	22303793
Pubmed	Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription.	ATR ATM	1.95e-05	2	154	2	31114877
Pubmed	Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.	ATR ATM	1.95e-05	2	154	2	35011623
Pubmed	Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.	CREBBP EP300	1.95e-05	2	154	2	34732714
Pubmed	IL-1 receptor deficiency slows progression to diabetes in the NOD mouse.	IL1R1 IL1RAP	1.95e-05	2	154	2	14693705
Pubmed	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	CREBBP EP300	1.95e-05	2	154	2	34019788
Pubmed	The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo.	ATR ATM	1.95e-05	2	154	2	26517239
Pubmed	Histamine regulates pancreatic carcinoma cell growth through H3 and H4 receptors.	HRH4 HRH3	1.95e-05	2	154	2	18345506
Pubmed	DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress.	ATR ATM	1.95e-05	2	154	2	21593482
Pubmed	A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function.	ATR ATM	1.95e-05	2	154	2	25232030
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	1.95e-05	2	154	2	15860545
Pubmed	ATM acts downstream of ATR in the DNA damage response signaling of bystander cells.	ATR ATM	1.95e-05	2	154	2	18757420
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	1.95e-05	2	154	2	29460469
Pubmed	Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study.	HRH4 HRH3	1.95e-05	2	154	2	22118942
Pubmed	Cellular responses to the DNA strand-scission enediyne C-1027 can be independent of ATM, ATR, and DNA-PK kinases.	ATR ATM	1.95e-05	2	154	2	11927575
Pubmed	In Vivo and In Vitro Effects of ATM/ATR Signaling Pathway on Proliferation, Apoptosis, and Radiosensitivity of Nasopharyngeal Carcinoma Cells.	ATR ATM	1.95e-05	2	154	2	28820634
Pubmed	ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.	ATR ATM	1.95e-05	2	154	2	29279380
Pubmed	ATR regulates fragile site stability.	ATR ATM	1.95e-05	2	154	2	12526805
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	1.95e-05	2	154	2	24551300
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	1.95e-05	2	154	2	33911074
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	1.95e-05	2	154	2	9018065
Pubmed	Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.	CREBBP EP300	1.95e-05	2	154	2	24648406
Pubmed	CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.	CREBBP EP300	1.95e-05	2	154	2	30135524
Pubmed	Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.	CREBBP EP300	1.95e-05	2	154	2	16596650
Pubmed	The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression.	NUP98 FOXK1	1.95e-05	2	154	2	25852164
GeneFamily	Histamine receptors	HRH4 HRH3	1.95e-04	4	104	2	187
GeneFamily	Short chain dehydrogenase/reductase superfamily	RDH8 DECR2 HSD17B11 HSDL1	9.65e-04	76	104	4	743
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASS4 IP6K3 AGPAT4 ITGA4 CREBBP CYFIP2 GVINP1 ADAMDEC1 IQGAP3	5.51e-09	162	154	9	93bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASS4 IP6K3 AGPAT4 ITGA4 CREBBP GVINP1 IQGAP3	1.33e-06	158	154	7	91d265e95156f16459924d3e4dd11c180e164eee
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	ATR NOL6 FAM120A MYH14 PIK3CB GCN1 IQGAP3	1.39e-06	159	154	7	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PGM2L1 OPN1SW PRDM8 ACKR3 ELOVL3 HCRTR1	7.61e-06	135	154	6	641d42a005ff61f21e6cda02bfbd0bd1d4ba2faa
ToppCell	droplet-Liver-LIVER_NPC-30m-Lymphocytic-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASS4 CDR2 PTPRU CLSTN1 ACMSD	1.09e-05	84	154	5	6c8018d65df335c81fe4099a34e0053c8dbcf88d
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ZNF862 CLSTN1 MYH14 AGTR2 ELOVL3 PAQR7	1.61e-05	154	154	6	1c62290a2558fd6401b27de5a867d243b143b00a
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR2 ITGA11 FBXL16 HRH4 ACMSD FAM135A	1.74e-05	156	154	6	5caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR2 ITGA11 FBXL16 HRH4 ACMSD FAM135A	1.74e-05	156	154	6	758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPO PGM2L1 ITGA4 ADAMTS7 SLC9A7 RMC1	3.11e-05	173	154	6	b367b62309389e8b6a65de83c2434dc8ec905985
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZYG11A LRRC70 LRRC55 SH3TC1 HAPLN3 NOS2	3.53e-05	177	154	6	76f5df101c693e5fa61554244d877fc8169ee66f
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	LRRC8C PIGB GPR173 SLC25A12 WDFY3 IL1R1	3.65e-05	178	154	6	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	RAP1GAP TMC7 HAPLN3 SLX4 PAQR7	3.69e-05	108	154	5	ee924deacd14ea404fda80ed633960143fd474c0
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF AGPAT4 SLC43A3 LRRC70 ACKR3 ITPRIP	4.13e-05	182	154	6	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN1 ADAMTS7 GPT2 IL1RAP GCN1 UNC80	4.13e-05	182	154	6	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7\|TCGA-Prostate / Sample_Type by Project: Shred V9	NELFCD TUT7 RIPK2 CENPO ULK3 TARBP1	4.13e-05	182	154	6	af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic-cDC1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	F2RL2 FANCD2 GVINP1 SLC9A7 GPR132 IQGAP3	4.25e-05	183	154	6	ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	F2RL2 FANCD2 GVINP1 SLC9A7 GPR132 IQGAP3	4.25e-05	183	154	6	e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCell	PND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	F2RL2 FANCD2 GVINP1 SLC9A7 GPR132 IQGAP3	4.25e-05	183	154	6	263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF AGPAT4 SLC43A3 LRRC70 ACKR3 ITPRIP	4.39e-05	184	154	6	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	facs-Kidney-nan-18m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPK2 PSMB9 ITGA4 SLC9A7 GPR132 CDH17	4.52e-05	185	154	6	a3b937163346d729115e6335336e33d3e71fccb0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCG CPT1B CYFIP2 MYH14 KLHL30 KBTBD12	4.94e-05	188	154	6	4db566f3f708e66730aa9e16f4d73d91dc534177
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCG CPT1B CYFIP2 MYH14 KLHL30 KBTBD12	4.94e-05	188	154	6	6704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PIGB FAM120A PIK3CB ATM IQGAP3 PAQR7	5.24e-05	190	154	6	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCG CPT1B CYFIP2 MYH14 KLHL30 KBTBD12	5.40e-05	191	154	6	543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell	facs-Heart-LV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCG CPT1B CYFIP2 MYH14 KLHL30 KBTBD12	5.40e-05	191	154	6	9d7d680da3979e256191b534ebd14c5383e0cf93
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	USP34 PGM2L1 CLSTN1 CYFIP2 FBXL16 UNC80	5.88e-05	194	154	6	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F2RL2 ADAMDEC1 ADAMTS7 ACKR3 IL1R1 TCTN1	6.40e-05	197	154	6	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
Drug	NF-058	PTGES2 IL1R1 IL1RAP	1.63e-05	8	153	3	CID000369605
Drug	cyclopropyl ketone	SHMT1 HRH4 HRH3	1.63e-05	8	153	3	CID000070721
Drug	Spiperone [749-02-0]; Down 200; 10.2uM; PC3; HT_HG-U133A	ZNF862 BAZ1B GRPR SEMA4G ST3GAL6 GUCY1B1 TARBP1 TCTN1	3.85e-05	186	153	8	5777_DN
Drug	impentamine	HRH4 HRH3	4.49e-05	2	153	2	CID009793868
Drug	curlone	PTGES2 NOS2	4.49e-05	2	153	2	CID000196216
Drug	bonanzin	PTGES2 NOS2	4.49e-05	2	153	2	CID005379563
Drug	homohistamine	HRH4 HRH3	4.49e-05	2	153	2	CID000170389
Drug	aplysamine	HRH4 HRH3	4.49e-05	2	153	2	CID000362025
Drug	connessine	HRH4 HRH3	4.49e-05	2	153	2	CID000002860
Drug	VUF 8328	HRH4 HRH3	4.49e-05	2	153	2	CID010176414
Drug	SC-359	HRH4 HRH3	4.49e-05	2	153	2	CID000022970
Drug	iodophenpropit	HRH4 HRH3	4.49e-05	2	153	2	CID003035746
Drug	immethridine	HRH4 HRH3	4.49e-05	2	153	2	CID009989505
Drug	Cipralisant [inn]	HRH4 HRH3	4.49e-05	2	153	2	CID006433105
Drug	phenoxytoluene	HRH4 HRH3	4.49e-05	2	153	2	CID000070352
Drug	imbutamine	HRH4 HRH3	4.49e-05	2	153	2	CID013499360
Drug	proxyfan	HRH4 HRH3	4.49e-05	2	153	2	CID006421522
Drug	JNJ7777120	HRH4 HRH3	4.49e-05	2	153	2	CID004908365
Drug	santin	PTGES2 NOS2	4.49e-05	2	153	2	CID005281695
Drug	burimamide	HRH4 HRH3	4.49e-05	2	153	2	CID003032915
Drug	piperidine-1-carbothioamide	HRH4 HRH3	4.49e-05	2	153	2	CID001551232
Drug	methimepip	HRH4 HRH3	4.49e-05	2	153	2	CID011313836
Drug	AC1O46V6	HRH4 HRH3	4.49e-05	2	153	2	CID006400683
Drug	semustine; Up 200; 100uM; PC3; HT_HG-U133A	CENPO B3GNT3 CPT1B ST3GAL6 AKR1C3 IL1RAP TCTN1 WDTC1	5.19e-05	194	153	8	7492_UP
Drug	Benfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A	USP34 ZNF862 BAZ1B SLC43A3 PTPRU CPT1B EHBP1L1 CHST3	5.19e-05	194	153	8	2621_UP
Drug	Esculin Hydrate [531-75-9]; Down 200; 11.8uM; PC3; HT_HG-U133A	PTGES2 ZNF862 CENPO BAZ1B CNIH3 ATM IL1RAP WDTC1	5.38e-05	195	153	8	6310_DN
Drug	Tiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A	SGCG ZNF862 BAZ1B GRPR EHBP1L1 MYH14 WDFY3 WDTC1	5.78e-05	197	153	8	2259_DN
Drug	Gramine [87-52-5]; Down 200; 23uM; MCF7; HT_HG-U133A	ZNF862 BAZ1B PTPRU CPT1B EHBP1L1 MGAT1 ATM WDTC1	5.99e-05	198	153	8	2799_DN
Drug	Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A	USP34 ZNF862 BAZ1B B3GNT3 EHBP1L1 ATM CABIN1 WDTC1	5.99e-05	198	153	8	2251_DN
Drug	Benzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	ZNF862 SEMA4G CNIH3 EHBP1L1 ADAMTS7 MYH14 IL1R1 WDTC1	6.43e-05	200	153	8	6839_UP
Drug	mangrove	NPC1 GPAM CPT1B FANCD2 MGAT1 SLC25A12 GUCY1B1 PIK3CB SLC25A13 DECR2 ACMSD NOS2	7.98e-05	468	153	12	CID000000965
Drug	pterin	SHMT1 FANCD2 AKR1C3 NOS2 EP300 PAQR7	9.09e-05	108	153	6	CID000073000
Drug	tsuwabukinonol	PTGES2 GPAM ITGA4 AGTR2	1.09e-04	37	153	4	CID006440419
Drug	1,5-diphenyl-3-dimethylaminopyrrolidine	HRH4 HRH3	1.34e-04	3	153	2	CID003016476
Drug	imetit	HRH4 HRH3	1.34e-04	3	153	2	ctd:C077430
Drug	Da-4626	HRH4 HRH3	1.34e-04	3	153	2	CID000134179
Drug	DA 4360	HRH4 HRH3	1.34e-04	3	153	2	CID000134176
Drug	Lupitidinum	HRH4 HRH3	1.34e-04	3	153	2	CID000051670
Drug	AHR-9294	HRH4 HRH3	1.34e-04	3	153	2	CID000134395
Drug	AC1L18BD	ATM ACMSD	1.34e-04	3	153	2	CID000000028
Drug	AC1L61GL	HRH4 HRH3	1.34e-04	3	153	2	CID000284703
Drug	2,3,4,5-tetrahydro-1,5-benzothiazepine	HRH4 HRH3	1.34e-04	3	153	2	CID000093962
Drug	bilastine	HRH4 HRH3	1.34e-04	3	153	2	CID000185460
Drug	3-amino-4-methylfurazan	HRH4 HRH3	1.34e-04	3	153	2	CID000028674
Drug	plocamadiene A	HRH4 HRH3	1.34e-04	3	153	2	CID006441110
Drug	6-azidoketanserin	HRH4 HRH3	1.34e-04	3	153	2	CID003035767
Drug	thiaburimamide	HRH4 HRH3	1.34e-04	3	153	2	CID003034473
Drug	2-naphthalenesulfonyl chloride	HRH4 HRH3	1.34e-04	3	153	2	CID000007125
Drug	sapindoside C	PTGES2 NOS2	1.34e-04	3	153	2	CID006325966
Drug	N'(Me),5(Me)histamine	HRH4 HRH3	1.34e-04	3	153	2	CID000104662
Drug	diethyl 2-chloroazulene-1,3-dicarboxylate	PTGES2 NOS2	1.34e-04	3	153	2	CID010244674
Drug	N-methylhistamine	HRH4 HRH3	1.34e-04	3	153	2	ctd:C048140
Drug	SU416	HRH4 HRH3	1.34e-04	3	153	2	CID000012656
Drug	SKF 91486	HRH4 HRH3	1.34e-04	3	153	2	CID000182527
Drug	phenoxymethyl	HRH4 HRH3	1.34e-04	3	153	2	CID000134735
Drug	E-2-P	HRH4 HRH3	1.34e-04	3	153	2	CID000132894
Drug	Salicylic Acid	UGT1A7 PSMB9 AKR1C3 NOS2	1.34e-04	39	153	4	ctd:D020156
Drug	pyruvic acid	VWF SGCG SHMT1 PGM2L1 CPT1B PLEKHM1 FANCD2 SLC25A12 GPT2 NOS2 SDHB	1.44e-04	424	153	11	CID000001060
Drug	thymoquinone	UGT1A7 UGT1A5 GPT2 NOS2	1.48e-04	40	153	4	CID000010281
Disease	ataxia telangiectasia (implicated_via_orthology)	ATR ATM	2.30e-05	2	142	2	DOID:12704 (implicated_via_orthology)
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.30e-05	2	142	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	2.30e-05	2	142	2	cv:C4551859
Disease	common bile duct disease (implicated_via_orthology)	SLC25A12 SLC25A13	2.30e-05	2	142	2	DOID:4137 (implicated_via_orthology)
Disease	Menke-Hennekam syndrome	CREBBP EP300	2.30e-05	2	142	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	2.30e-05	2	142	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	2.30e-05	2	142	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.30e-05	2	142	2	C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	2.30e-05	2	142	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	2.30e-05	2	142	2	C0035934
Disease	citrullinemia (implicated_via_orthology)	SLC25A12 SLC25A13	6.88e-05	3	142	2	DOID:9273 (implicated_via_orthology)
Disease	intrahepatic cholestasis (implicated_via_orthology)	SLC25A12 SLC25A13	1.37e-04	4	142	2	DOID:1852 (implicated_via_orthology)
Disease	pancreatic cancer (is_implicated_in)	ITGA11 ATR UGT1A7 ITGA4 ATM	2.13e-04	112	142	5	DOID:1793 (is_implicated_in)
Disease	vitamin D measurement	SNX4 UGT1A7 UGT1A5 GPAM NPHS2 DHCR7 HSD17B11 NPAS2	2.33e-04	336	142	8	EFO_0004631
Disease	lumbar disc degeneration	DYNC2H1 MYH14 CHST3	3.27e-04	28	142	3	EFO_0004994
Disease	anxiety, smoking behaviour measurement	PRDM8 UNC80	4.75e-04	7	142	2	EFO_0005230, EFO_0005671
Disease	Disorders of Sex Development	DHCR7 AKR1C3	4.75e-04	7	142	2	C0036875
Disease	X-11793--oxidized bilirubin measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0021260
Disease	Succinimide measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0022118
Disease	X-11530 measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0021249
Disease	focal segmental glomerulosclerosis (is_marker_for)	RAP1GAP VWF	6.32e-04	8	142	2	DOID:1312 (is_marker_for)
Disease	sulfate of piperine metabolite C16H19NO3 (2) measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0801034
Disease	cholelithiasis, bilirubin measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0004570, EFO_0004799
Disease	X-11522 measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0800696
Disease	X-10458 measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0800692
Disease	X-24849 measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0800909
Disease	serum N-desmethylclozapine measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0600043
Disease	plasma clozapine measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0600038
Disease	membrane-associated progesterone receptor component 1 measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0802740
Disease	X-16946 measurement	UGT1A7 UGT1A5	6.32e-04	8	142	2	EFO_0800766
Disease	X-11442 measurement	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0021236
Disease	X-11441 measurement	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0021235
Disease	circulating cell free DNA measurement	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0004739
Disease	sulfate of piperine metabolite C18H21NO3 (3) measurement	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0801037
Disease	sulfate of piperine metabolite C18H21NO3 (1) measurement	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0801036
Disease	X-11880 measurement	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0800698
Disease	protein-tyrosine kinase 6 measurement	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0020691
Disease	testis-specific chromodomain protein Y 1 measurement	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0802127
Disease	bilirubin measurement, response to xenobiotic stimulus	UGT1A7 UGT1A5	8.10e-04	9	142	2	EFO_0004570, GO_0009410
Disease	fibrinogen measurement, coronary artery disease	DYNC2H1 AGPAT4 TAS2R1 PRDM8 IL1R1	9.16e-04	154	142	5	EFO_0001645, EFO_0004623
Disease	bilirubin measurement, response to tenofovir	UGT1A7 UGT1A5	1.01e-03	10	142	2	EFO_0004570, EFO_0009279
Disease	X-21448 measurement	UGT1A7 UGT1A5	1.01e-03	10	142	2	EFO_0800816
Disease	UDP-glucuronosyltransferase 1-6 measurement	UGT1A7 UGT1A5	1.01e-03	10	142	2	EFO_0802185
Disease	X-23974 measurement	UGT1A7 UGT1A5	1.01e-03	10	142	2	EFO_0800867
Disease	abdominal aortic calcification measurement	RAP1GAP NOL6	1.01e-03	10	142	2	EFO_0010272
Disease	interleukin 1 receptor-like 1 measurement	IL1R1 NPAS2	1.23e-03	11	142	2	EFO_0008168
Disease	T-cell acute lymphoblastic leukemia (is_implicated_in)	NUP98 AKR1C3	1.23e-03	11	142	2	DOID:5603 (is_implicated_in)
Disease	pregnenetriol sulfate measurement	UGT1A7 UGT1A5	1.23e-03	11	142	2	EFO_0800586
Disease	plasma N-desmethylclozapine measurement	UGT1A7 UGT1A5	1.23e-03	11	142	2	EFO_0600039
Disease	histidine betaine (hercynine) measurement	UGT1A7 UGT1A5	1.23e-03	11	142	2	EFO_0800972
Disease	X-21796 measurement	UGT1A7 UGT1A5	1.23e-03	11	142	2	EFO_0800825
Disease	insomnia, bilirubin measurement	UGT1A7 UGT1A5	1.23e-03	11	142	2	EFO_0004570, EFO_0004698
Disease	aldosterone measurement	UGT1A7 UGT1A5	1.23e-03	11	142	2	EFO_0010219
Disease	p-cresol glucuronide measurement	UGT1A7 UGT1A5	1.47e-03	12	142	2	EFO_0800079
Disease	biliverdin measurement	UGT1A7 UGT1A5	1.47e-03	12	142	2	EFO_0021033
Disease	acute myeloid leukemia (implicated_via_orthology)	NUP98 CREBBP	1.47e-03	12	142	2	DOID:9119 (implicated_via_orthology)
Disease	Leukemia, Myelocytic, Acute	NUP98 CREBBP FANCD2 EP300 SLX4	1.53e-03	173	142	5	C0023467
Disease	metabolite measurement	UGT1A7 UGT1A5 PSMB9 GPAM AKR1C3 DECR2 ZMYM1 ACMSD CABIN1	1.61e-03	560	142	9	EFO_0004725
Disease	pregnenetriol disulfate measurement	UGT1A7 UGT1A5	1.73e-03	13	142	2	EFO_0800587
Disease	retinol dehydrogenase 16 measurement	UGT1A7 UGT1A5	1.73e-03	13	142	2	EFO_0802007
Disease	Fanconi anemia	FANCD2 SLX4	2.01e-03	14	142	2	cv:C0015625
Disease	C-reactive protein measurement	NPC1 USP34 CWF19L2 RAP1GAP SGCG BAZ1B CYFIP2 LRRC55 SLC9A7 RMC1 IL1R1 GCN1 HCRTR1 USP47	2.09e-03	1206	142	14	EFO_0004458
Disease	factor VIII measurement, coronary artery disease	VWF DYNC2H1 AGPAT4 PRDM8	2.21e-03	113	142	4	EFO_0001645, EFO_0004630
Disease	Proteinuria	VWF ADAMTS7	2.32e-03	15	142	2	HP_0000093
Disease	Diffuse Large B-Cell Lymphoma	CREBBP PIK3CB EP300	2.38e-03	55	142	3	C0079744
Disease	non-high density lipoprotein cholesterol measurement	NPC1 USP34 UGT1A7 UGT1A5 AGPAT4 GPAM DDX56 ABCA9 CNIH3 ULK3	2.44e-03	713	142	10	EFO_0005689
Disease	von Willebrand factor measurement, coronary artery disease	VWF DYNC2H1 AGPAT4 PRDM8	2.58e-03	118	142	4	EFO_0001645, EFO_0004629
Disease	diabetic retinopathy (implicated_via_orthology)	ITGA4 EP300	2.64e-03	16	142	2	DOID:8947 (implicated_via_orthology)
Disease	phosphorus measurement	RAP1GAP IP6K3	2.64e-03	16	142	2	EFO_0004861
Disease	Benign neoplasm of stomach	ATR ATM	2.98e-03	17	142	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ATR ATM	2.98e-03	17	142	2	C0496905
Disease	low density lipoprotein cholesterol measurement, body fat percentage	UGT1A7 UGT1A5	2.98e-03	17	142	2	EFO_0004611, EFO_0007800
Disease	Carcinoma in situ of stomach	ATR ATM	2.98e-03	17	142	2	C0154060
Disease	pre-eclampsia (biomarker_via_orthology)	ITGA4 AKR1C3	2.98e-03	17	142	2	DOID:10591 (biomarker_via_orthology)
Disease	X-21441 measurement	UGT1A7 UGT1A5	2.98e-03	17	142	2	EFO_0800814
Disease	angina pectoris	DYNC2H1 PRDM8 EHBP1L1 ADAMTS7	3.18e-03	125	142	4	EFO_0003913
Disease	Adenocarcinoma of lung (disorder)	ATR SHMT1 CREBBP ATM EP300	3.27e-03	206	142	5	C0152013
Disease	serum alanine aminotransferase measurement	NPC1 PTGES2 BTBD8 SGCG SHMT1 BAZ1B GPAM CYFIP2 ADAMTS7 RMC1 IL1R1	3.29e-03	869	142	11	EFO_0004735
Disease	angiopoietin-related protein 1 measurement	UGT1A7 UGT1A5	3.35e-03	18	142	2	EFO_0801382
Disease	Bone marrow hypocellularity	FANCD2 SLX4	3.35e-03	18	142	2	C1855710
Disease	bipolar disorder (is_marker_for)	RAP1GAP VWF	3.73e-03	19	142	2	DOID:3312 (is_marker_for)
Disease	Stomach Carcinoma	ATR ATM	4.55e-03	21	142	2	C0699791
Disease	tissue factor measurement	UGT1A7 UGT1A5	4.55e-03	21	142	2	EFO_0010623

Protein segments in the cluster

Peptide	Gene	Start	Entry
AFPFYNTVCILRKLF	NAIP	601	Q13075
VYSPDCRFHSFKKVL	GPT2	306	Q8TD30
SYLDSVHFFRPKCLR	EP300	1396	Q09472
RLSEHCRLYFGALFK	CASS4	671	Q9NQ75
IFRLLKHAICAAEFY	CXorf58	61	Q96LI9
VECHPYFNRSKLLDF	AKR1C3	191	P42330
AEYGHRCSPLFFLKS	ABCA9	426	Q8IUA7
NKAFHLFCLRPALYE	BAZ1B	1206	Q9UIG0
KFSYIPLASCHFPID	GVINP1	291	Q7Z2Y8
FIATCYFGIRKHLLK	AGTR2	226	P50052
ISYLDSIHFFRPRCL	CREBBP	1431	Q92793
YAAAERLKCSLFVHP	ACMSD	161	Q8TDX5
YVHGCRLIFLFRQDP	CLSTN1	421	O94985
HVSVPFLLAYCSSKF	HSD17B11	176	Q8NBQ5
FQVLLYTSLPDFCHK	DHCR7	106	Q9UBM7
LHCRPANEYFAEKLR	ADAMTS7	631	Q9UKP4
LPNKATLGHFYERCI	ITPRIP	136	Q8IWB1
FLPKYLSSPRCAALH	KLHL30	456	Q0D2K2
LEFYCHLLRGSLNPK	NPAS2	166	Q99743
YPRFCAFAHDIDQKL	NOS2	631	P35228
FDLINHYFCDLLPLL	OR8G1	171	Q15617
TPLRDVCFHLLKLYS	NUP98	1486	P52948
PALLYHKCQVVFFLL	PAQR7	236	Q86WK9
FKACHLTLTLDDYLF	LRRC55	246	Q6ZSA7
LKNPLGTFIFCHAYL	PRAMEF17	291	Q5VTA0
RLHRYDVFCFATALK	HAPLN3	251	Q96S86
RDLFYKLAEAHPDCL	NELFCD	156	Q8IXH7
CLDKLLHYRPSAELF	MGAT1	121	P26572
KCPLFEHFLKFNYST	IL1RAP	46	Q9NPH3
KSLLCHLPRIYQAFL	DDX56	181	Q9NY93
CRDHSDPRQTFLYKL	FAM135A	1391	Q9P2D6
KADLLLEPCSHYRFL	MYH14	316	Q7Z406
PVILRLFSFSYCKSH	OR51B2	156	Q9Y5P1
DRFTAICKPLHYFVV	OR2W1	121	Q9Y3N9
LPFLLKRFQYCHSHV	OR51G1	161	Q8NGK1
PYKACLSELFFFHLL	OR3A4P	96	P47883
YPKFCGTFAILHVRD	PGM2L1	516	Q6PCE3
LYCFDSSQFPKHLIV	CWF19L2	676	Q2TBE0
HCLQEASPRYKSLRF	GHDC	461	Q8N2G8
LHQVPYAVKGCFRFL	NOL6	141	Q9H6R4
AYRHLFCPDLLRDKV	DECR2	16	Q9NUI1
AFCAILHRFYPDKID	EHBP1L1	1071	Q8N3D4
GLFFFLPCLDTYHKV	NPHS2	151	Q9NP85
CAPLLRYLSHSEFKD	GCN1	246	Q92616
YTFCKAFPFHIIFDR	GUCY1B1	211	Q02153
LCNIPYYFSAHALKL	FAM120A	191	Q9NZB2
PLRFHLKYEADVLFT	ITGA11	946	Q9UKX5
HFFCDVLPLYRLSCI	OR5K3	176	A6NET4
FDKLSPLHERIYCAL	PSMB9	51	P28065
RRFDLFDFCYHLLKV	CYFIP2	1196	Q96F07
VTRLPYCRKEINHFF	OR6M1	161	Q8NGM8
FKPETFRKFLALYLH	MRPL37	406	Q9BZE1
LCSEYPENKRHRFLL	IP6K3	186	Q96PC2
PRVVYCIHALSLFLF	IQGAP3	136	Q86VI3
PKAFVQLRHLYFLFL	LRRC70	101	Q7Z2Q7
FRDLYLPASRKLFCS	RDH8	216	Q9NYR8
LLSYPCAKAPHFSRL	PTPRU	181	Q92729
LFCVTLPFKIAYHLN	F2RL2	141	O00254
CLFRFFKNSYSPLLL	NPC1	816	O15118
DKCLQSPIYFFLGHL	OR9A1P	51	Q8NGU1
YAICHPLLFKSTARR	HCRTR1	146	O43613
AIRTIHEKFLYFLPA	DYNC2H1	336	Q8NCM8
DFYRSCYKVLIPHLV	ATM	1246	Q13315
LCHLLQYFLKFVPAG	ATR	346	Q13535
LFEKHPCLYILTFGF	CEPT1	311	Q9Y6K0
FYLLSFLLERKPCTI	BLCAP	31	P62952
FRLCLSRFPQHYKSL	CABIN1	1516	Q9Y6J0
AHFFCQTYIRPKVKA	ELOVL3	251	Q9HB03
PSFACLKELYDLRQH	CDR2	156	Q01850
AHKAVLLARVPDFYF	BTBD8	71	Q5XKL5
CVNPFALYLLSKSFR	GRPR	316	P30550
LVPGALFHLYAACKS	GJE1	86	A6NN92
LSFQEPHFYLRCLGK	FOXK1	151	P85037
IFSILHYIPFTCRLE	ACKR3	276	P25106
SFDPCFYRDLLLVHR	B3GNT3	331	Q9Y2A9
RALHKAPYYFLLDLC	GPR173	51	Q9NS66
LYPLCHHSFRRAFTK	HRH3	411	Q9Y5N1
RLLYCIKADPHCLNF	ITGA4	886	P13612
AYPFLKARFNLDHIL	KNCN	56	A6PVL3
FPFCARLLYKDLTAT	CENPO	231	Q9BU64
ICDFYSLIRLHFIPR	HSDL1	41	Q3SXM5
RLAKDYTGLFFCHPL	CDH17	666	Q12864
DFVTLCIIHRYLDFK	CFAP69	741	A5D8W1
IESRFYKHPFTCFAK	IL1R1	301	P14778
LAHFRDRGKFCLTYE	CPT1B	576	Q92523
LHVCLKYGRLFVEAF	FANCD2	1291	Q9BXW9
YDRFLAICKPLHYAT	OR10G6	141	Q8NH81
KFPCHRLVLAAFSPY	KBTBD12	41	Q3ZCT8
AFLAFERYIVICKPF	OPN1SW	126	P03999
VIDHYFCDLQPLFKL	OR4B1	171	Q8NGF8
RLFHPKLIIAGTSCY	SHMT1	191	P34896
FLVCFAPYHLVLLVK	GPR132	251	Q9UNW8
TPELFKYFSQHLPRC	FBXL16	461	Q8N461
SFVNPLLYPLCHKRF	HRH4	351	Q9H3N8
KELFCELSPLEFRLY	PLEKHM1	551	Q9Y4G2
SHKEFRFIYPVLPFC	PIGB	356	Q92521
TLLSYFYKCPVRLHL	MRPS24	141	Q96EL2
IYLERFPIFKACFSA	UTP18	291	Q9Y5J1
ASHPILCRDKIFYLF	SNX4	166	O95219
SIVCYLSLPHLKFAR	SLC29A2	206	Q14542
LYCLKIASFSHPTFL	TAS2R3	106	Q9NYW6
LLHFFCLPFIVKHAY	TMEM217B	131	A0A494BZU4
EKELLSLFCFFSLPH	HPS3	336	Q969F9
FEFPYVAHLRFRCPK	PRDM8	166	Q9NQV8
FILFCHNIKAPYIAS	GPAM	241	Q9HCL2
PAYFRSLLCSKHPAA	SKIDA1	211	Q1XH10
LECNPTARIYRKHFL	RAP1GAP	81	P47736
HPFLCAADFRKIASL	ST3GAL6	61	Q9Y274
FALCSLLRHFPYAQR	SIL1	291	Q9H173
AEHFYLKALSLCNSP	SH3TC1	1211	Q8TE82
ILLTFFHPFLVYREC	SLC43A3	466	Q8NBI5
PFCSKVRAFLDFHAL	PTGES2	111	Q9H7Z7
AHEYCLKFTKLLRFA	SUPT7L	186	O94864
LKYEPFLDCALSRFL	PIK3CB	646	P42338
YSPLLKLACSHDFTF	OR5P3	181	Q8WZ94
DSFKRLIYPLLCREF	SRBD1	491	Q8N5C6
FLFPLYAKEIHSRVD	SGCG	86	Q13326
LKFNRERITYCHLPF	STXBP5L	151	Q9Y2K9
HKFVLYARCPLLIQY	SLX4	706	Q8IY92
SCRAHFERYLLSQKP	ADAMDEC1	391	O15204
KKILFYCHFPDLLLT	ALG2	131	Q9H553
YCHFPDLLLTKRDSF	ALG2	136	Q9H553
AIYFPVYAHCKLLLA	SLC25A12	496	O75746
AKACFLRDIPFSAIY	SLC25A13	486	Q9UJS0
FLCDLYVLEHFITPL	CHST3	196	Q7LGC8
CFLLRKLVLPEYSIH	CNIH3	61	Q8TBE1
VFYCAKVASVRHPLF	TAS2R1	101	Q9NYW7
HFRLARCLFELKYVA	WDTC1	436	Q8N5D0
KAFYFLNLCLIHERI	ZNF20	206	P17024
FACHQFYILHRKPFV	UNC80	2256	Q8N2C7
STLVKCLYLFFDLPH	WDFY3	151	Q8IZQ1
SFLKARLICHIPLYE	SEMA4G	286	Q9NTN9
PLHDFYCSRLLDLVF	VWF	1266	P04275
LFAECHKVLAPATFY	VWF	2146	P04275
FLQYHVLSDSKPLAC	RMC1	521	Q96DM3
FLFAKHYLFCIAAIL	TMEM247	196	A6NEH6
HKARFSYILPILGIC	RIPK2	71	O43353
FCIHITNYKPALSFI	TCTN1	151	Q2MV58
CDARKGLRFLHFPYL	USP47	371	Q96K76
TDPFHLCAAVLAKYL	UGT1A5	151	P35504
CHFLLDFLSIYRPLS	ZNF862	841	O60290
ADFVYKHIVPACFLA	XPOT	866	O43592
DPLLYKCSFRTRLHF	VPS13B	226	Q7Z7G8
LLACILQLHYFHRPF	PIEZO1	691	Q92508
ATFHPLKDYCLETIF	TARBP1	1346	Q13395
YAHFLDLSIIRFCKE	ZMYM1	746	Q5SVZ6
PEKYFFLIHCEGTRF	AGPAT4	166	Q9NRZ5
CSRYIHDLFPSLIKN	USP34	421	Q70CQ2
TKLHCFPLLETALFF	SLC9A7	351	Q96T83
LAKLQDPFSLYRCHT	SDHB	231	P21912
VFQHKLPDCSLRLYG	TUT7	326	Q5VYS8
LCFLYHEPSKLYQIF	TBC1D19	376	Q8N5T2
VTCLLFKALKNFPHY	ZYG11A	426	Q6WRX3
EHLFCPYFFKNVLEI	UGT1A7	216	Q9HAW7
LFVDFPRKLLVTYCS	TMC7	511	Q7Z402
LYCKALDFFVPALHY	ULK3	306	Q6PHR2
PSHLFLCNKIRYLDL	LRRC8C	676	Q8TDW0