Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A18 SLC25A16 SLC5A3 SLC2A10 SLC8A3 SLC25A12 SLC12A9 SLC17A9 SLC20A2 SLC25A13 SLC25A10 SLC16A11 SLC35A5	1.31e-06	296	167	13	GO:0015291
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	TPTE INPP5E TPTE2	5.68e-06	5	167	3	GO:0016314
GeneOntologyMolecularFunction	aspartate:glutamate, proton antiporter activity	SLC25A12 SLC25A13	6.95e-05	2	167	2	GO:0000515
GeneOntologyMolecularFunction	3-sulfino-L-alanine: proton, glutamate antiporter activity	SLC25A12 SLC25A13	6.95e-05	2	167	2	GO:0000514
GeneOntologyMolecularFunction	transporter activity	SLC6A18 ATP8B3 CACNA1E TPTE SLC25A33 TPTE2 ATG2B SLC7A7 SLC25A16 KCNIP2 SLC5A3 SLC2A10 SLC8A3 PIEZO2 SLC25A12 SLC12A9 SLC17A9 SLC20A2 CLN3 SLC25A13 SLC25A10 KCNJ16 SLC16A11 SLC38A11 SLC35A5	7.11e-05	1289	167	25	GO:0005215
GeneOntologyMolecularFunction	olfactory receptor activity	OR10H5 OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 OR8G2P OR10G6 OR4S1 OR10J5 OR2V2 OR4C5	7.12e-05	431	167	13	GO:0004984
GeneOntologyMolecularFunction	phosphatidylinositol trisphosphate phosphatase activity	TPTE INPP5E TPTE2	9.02e-05	11	167	3	GO:0034594
GeneOntologyMolecularFunction	phosphatidylinositol phosphate phosphatase activity	TPTE INPP5E TPTE2 MTMR3	1.09e-04	30	167	4	GO:0052866
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A18 SLC25A16 SLC5A3 SLC2A10 SLC8A3 SLC25A12 SLC12A9 SLC17A9 SLC20A2 SLC25A13 SLC25A10 SLC16A11 SLC35A5	1.95e-04	477	167	13	GO:0022804
GeneOntologyMolecularFunction	C4-dicarboxylate transmembrane transporter activity	SLC25A12 SLC25A13 SLC25A10	2.43e-04	15	167	3	GO:0015556
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A18 CACNA1E TPTE SLC25A33 TPTE2 SLC7A7 SLC25A16 KCNIP2 SLC5A3 SLC2A10 SLC8A3 PIEZO2 SLC25A12 SLC12A9 SLC17A9 SLC20A2 SLC25A13 SLC25A10 KCNJ16 SLC16A11 SLC38A11 SLC35A5	3.48e-04	1180	167	22	GO:0022857
GeneOntologyMolecularFunction	amino acid:monoatomic cation antiporter activity	SLC25A12 SLC25A13	6.84e-04	5	167	2	GO:0140848
GeneOntologyMolecularFunction	phosphatase activity	TPTE EYA4 PLPP5 INPP5E DUSP1 TPTE2 HDDC2 MTMR3 TNS3	7.15e-04	287	167	9	GO:0016791
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC7A7 SLC25A16 SLC2A10 SLC25A12 SLC17A9 SLC25A13 SLC25A10 SLC16A11 SLC38A11	8.28e-04	293	167	9	GO:0008514
GeneOntologyMolecularFunction	antiporter activity	SLC25A16 SLC8A3 SLC25A12 SLC25A13 SLC25A10 SLC35A5	1.08e-03	138	167	6	GO:0015297
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	TPTE EYA4 GALNS PLPP5 INPP5E IARS1 DUSP1 TPTE2 HDDC2 PLA2G4D ZRANB3 PLA2G4C PXDNL MTMR3 CNOT1 TNS3	1.24e-03	807	167	16	GO:0016788
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate phosphatase activity	INPP5E TPTE2 MTMR3	1.45e-03	27	167	3	GO:0034593
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	SLC25A33 SLC25A16 SLC17A9 SLC35A5	1.50e-03	59	167	4	GO:0015932
GeneOntologyMolecularFunction	calcium ion binding	TPO CACNA1E NID2 COMP PCDHB3 CUBN PLA2G4D KCNIP2 BMP1 TGM2 THBS3 SLC25A12 PLA2G4C TLL2 SLC25A13	1.59e-03	749	167	15	GO:0005509
GeneOntologyMolecularFunction	symporter activity	SLC6A18 SLC5A3 SLC2A10 SLC12A9 SLC20A2 SLC16A11	1.66e-03	150	167	6	GO:0015293
GeneOntologyMolecularFunction	protein tyrosine phosphatase activity	TPTE EYA4 DUSP1 TPTE2 MTMR3	1.74e-03	103	167	5	GO:0004725
GeneOntologyMolecularFunction	chemorepellent activity	SEMA3F DPP4 SEMA3E	1.79e-03	29	167	3	GO:0045499
GeneOntologyBiologicalProcess	gluconeogenesis	RGPD4 HIF1A GAPDH PPP4R3B SLC25A12 SLC25A13 RGPD3 SLC25A10	3.11e-06	111	165	8	GO:0006094
GeneOntologyBiologicalProcess	hexose biosynthetic process	RGPD4 HIF1A GAPDH PPP4R3B SLC25A12 SLC25A13 RGPD3 SLC25A10	4.05e-06	115	165	8	GO:0019319
GeneOntologyBiologicalProcess	monosaccharide biosynthetic process	RGPD4 HIF1A GAPDH PPP4R3B SLC25A12 SLC25A13 RGPD3 SLC25A10	5.92e-06	121	165	8	GO:0046364
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR10H5 OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 OR8G2P OR10G6 OR4S1 OR10J5 OR2V2 OR4C5	4.65e-05	432	165	13	GO:0050911
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR10H5 OR5M1 OR6N2 OR5B2 OR11H7 DISC1 OR2V1 OR2J1 OR8G2P OR10G6 OR4S1 PIEZO2 OR10J5 OR2V2 OR4C5	7.07e-05	582	165	15	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR10H5 OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 KCNIP2 OR8G2P OR10G6 OR4S1 OR10J5 OR2V2 OR4C5	8.50e-05	524	165	14	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of smell	OR10H5 OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 OR8G2P OR10G6 OR4S1 OR10J5 OR2V2 OR4C5	9.77e-05	465	165	13	GO:0007608
GeneOntologyBiologicalProcess	hexose metabolic process	RGPD4 HIF1A GAPDH GDF2 PPP4R3B SLC25A12 SLC25A13 RGPD3 SLC25A10 POFUT2	1.00e-04	284	165	10	GO:0019318
GeneOntologyBiologicalProcess	negative regulation of mesenchymal cell apoptotic process	HIF1A SYNE1 WT1	1.36e-04	13	165	3	GO:2001054
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR10H5 OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 OR8G2P OR10G6 OR4S1 OR10J5 OR2V2 OR4C5	1.48e-04	485	165	13	GO:0050907
GeneOntologyBiologicalProcess	glucose metabolic process	RGPD4 HIF1A GAPDH GDF2 PPP4R3B SLC25A12 SLC25A13 RGPD3 SLC25A10	1.58e-04	244	165	9	GO:0006006
GeneOntologyBiologicalProcess	nucleobase-containing compound transport	RGPD4 SLC25A33 SLC25A16 SLC17A9 MCM3AP RGPD3 AGFG1 DDX39A SLC35A5	1.84e-04	249	165	9	GO:0015931
GeneOntologyBiologicalProcess	embryo development	TANC2 TPO SEMA3F EPOR HIF1A EYA4 DUSP1 MAP3K20 WT1 CUBN TBL1XR1 SLC2A10 ALX1 NDEL1 SEC24B CNTNAP2 KDM2B DHX35 DMBT1 ZNF281 TMEM100 POFUT2 CNOT1 SMAD1 SMAD5	1.94e-04	1437	165	25	GO:0009790
GeneOntologyBiologicalProcess	monosaccharide metabolic process	RGPD4 HIF1A GAPDH GDF2 PPP4R3B SLC25A12 SLC25A13 RGPD3 SLC25A10 POFUT2	2.04e-04	310	165	10	GO:0005996
GeneOntologyBiologicalProcess	mitochondrial transmembrane transport	HIF1A SLC25A33 SLC25A16 SLC8A3 SLC25A12 SLC25A13	2.11e-04	106	165	6	GO:1990542
GeneOntologyBiologicalProcess	detection of stimulus	OR10H5 OR5M1 OR6N2 OR5B2 OR11H7 DISC1 OR2V1 OR2J1 KCNIP2 OR8G2P OR10G6 OR4S1 PIEZO2 OR10J5 OR2V2 OR4C5	2.31e-04	722	165	16	GO:0051606
Domain	EGF_CA	TPO NID2 COMP CUBN BMP1 THBS3 TLL2	1.06e-05	86	164	7	PF07645
Domain	EGF_Ca-bd_CS	TPO NID2 COMP CUBN BMP1 THBS3 TLL2	2.34e-05	97	164	7	IPR018097
Domain	EGF_CA	TPO NID2 COMP CUBN BMP1 THBS3 TLL2	2.68e-05	99	164	7	PS01187
Domain	PTEN_C2	TPTE TPTE2 TNS3	3.60e-05	8	164	3	PF10409
Domain	PTEN_C2	TPTE TPTE2 TNS3	3.60e-05	8	164	3	SM01326
Domain	C2_TENSIN	TPTE TPTE2 TNS3	3.60e-05	8	164	3	PS51182
Domain	Tensin_lipid_phosphatase_dom	TPTE TPTE2 TNS3	3.60e-05	8	164	3	IPR029023
Domain	Tensin_C2-dom	TPTE TPTE2 TNS3	3.60e-05	8	164	3	IPR014020
Domain	LisH	TBL1Y TBL1XR1 TBL1X	5.37e-05	9	164	3	PF08513
Domain	PPASE_TENSIN	TPTE TPTE2 TNS3	5.37e-05	9	164	3	PS51181
Domain	CUB	CUBN CSMD3 BMP1 TLL2 DMBT1	6.85e-05	49	164	5	PF00431
Domain	CUB	CUBN CSMD3 BMP1 TLL2 DMBT1	7.56e-05	50	164	5	SM00042
Domain	-	CUBN CSMD3 BMP1 TLL2 DMBT1	9.14e-05	52	164	5	2.60.120.290
Domain	-	SLC25A33 SLC25A16 SLC25A12 SLC25A13 SLC25A10	1.00e-04	53	164	5	1.50.40.10
Domain	CUB	CUBN CSMD3 BMP1 TLL2 DMBT1	1.00e-04	53	164	5	PS01180
Domain	Mito_carr	SLC25A33 SLC25A16 SLC25A12 SLC25A13 SLC25A10	1.00e-04	53	164	5	PF00153
Domain	SOLCAR	SLC25A33 SLC25A16 SLC25A12 SLC25A13 SLC25A10	1.00e-04	53	164	5	PS50920
Domain	Mitochondrial_sb/sol_carrier	SLC25A33 SLC25A16 SLC25A12 SLC25A13 SLC25A10	1.00e-04	53	164	5	IPR018108
Domain	Mt_carrier_dom	SLC25A33 SLC25A16 SLC25A12 SLC25A13 SLC25A10	1.00e-04	53	164	5	IPR023395
Domain	EGF_CA	TPO NID2 COMP CUBN BMP1 THBS3 TLL2	1.02e-04	122	164	7	SM00179
Domain	EGF-like_Ca-bd_dom	TPO NID2 COMP CUBN BMP1 THBS3 TLL2	1.13e-04	124	164	7	IPR001881
Domain	CUB_dom	CUBN CSMD3 BMP1 TLL2 DMBT1	1.42e-04	57	164	5	IPR000859
Domain	Olfact_rcpt	OR10H5 OR5M1 OR6N2 OR5B2 OR2V1 OR2J1 OR8G2P OR10G6 OR4S1 OR10J5 OR2V2 OR4C5	1.89e-04	393	164	12	IPR000725
Domain	COMP	COMP THBS3	2.29e-04	3	164	2	PF11598
Domain	BMP_1/tolloid-like	BMP1 TLL2	2.29e-04	3	164	2	IPR015446
Domain	Thbs/COMP_coiled-coil	COMP THBS3	2.29e-04	3	164	2	IPR024665
Domain	EGF	TPO NID2 COMP CUBN BMP1 THBS3 TLL2 CNTNAP2 TENM1	2.37e-04	235	164	9	SM00181
Domain	EGF_3	TPO NID2 COMP CUBN BMP1 THBS3 TLL2 CNTNAP2 TENM1	2.37e-04	235	164	9	PS50026
Domain	EGF-like_dom	TPO NID2 COMP CUBN BMP1 THBS3 TLL2 CNTNAP2 TENM1	3.63e-04	249	164	9	IPR000742
Domain	EGF-like_CS	TPO NID2 COMP CUBN BMP1 THBS3 TLL2 CNTNAP2 TENM1	5.10e-04	261	164	9	IPR013032
Domain	EGF_2	TPO NID2 COMP CUBN BMP1 THBS3 TLL2 CNTNAP2 TENM1	5.69e-04	265	164	9	PS01186
Domain	WD40_repeat_CS	TBL1Y TBL1XR1 WDR38 LLGL1 GNB4 HERC1 TBL1X	6.22e-04	164	164	7	IPR019775
Domain	TSP_3	COMP THBS3	7.53e-04	5	164	2	PF02412
Domain	TSP3	COMP THBS3	7.53e-04	5	164	2	PS51234
Domain	TSP_CTER	COMP THBS3	7.53e-04	5	164	2	PS51236
Domain	Thrombospondin_3_rpt	COMP THBS3	7.53e-04	5	164	2	IPR017897
Domain	YD	NID2 TENM1	7.53e-04	5	164	2	IPR006530
Domain	TSP_type-3_rpt	COMP THBS3	7.53e-04	5	164	2	IPR028974
Domain	-	COMP THBS3	7.53e-04	5	164	2	4.10.1080.10
Domain	Thrombospondin_C	COMP THBS3	7.53e-04	5	164	2	IPR008859
Domain	TSP_C	COMP THBS3	7.53e-04	5	164	2	PF05735
Domain	Thrombospondin_3-like_rpt	COMP THBS3	7.53e-04	5	164	2	IPR003367
Domain	WD40/YVTN_repeat-like_dom	SEMA3F TBL1Y TBL1XR1 WDR38 SF3B3 LLGL1 GNB4 HERC1 TBL1X SEMA3E	7.73e-04	335	164	10	IPR015943
Domain	G-protein_beta_WD-40_rep	TBL1Y TBL1XR1 WDR38 GNB4 TBL1X	9.15e-04	85	164	5	IPR020472
Domain	Sec23/24_helical_dom	SEC24A SEC24B	1.12e-03	6	164	2	IPR006900
Domain	Sec23_24_beta_S	SEC24A SEC24B	1.12e-03	6	164	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24A SEC24B	1.12e-03	6	164	2	PF04810
Domain	Sec23_trunk	SEC24A SEC24B	1.12e-03	6	164	2	PF04811
Domain	Sec23_helical	SEC24A SEC24B	1.12e-03	6	164	2	PF04815
Domain	PEROXIDASE_1	TPO PXDNL	1.12e-03	6	164	2	PS00435
Domain	Peptidase_M12A	BMP1 TLL2	1.12e-03	6	164	2	IPR001506
Domain	Sec23_BS	SEC24A SEC24B	1.12e-03	6	164	2	PF08033
Domain	Astacin	BMP1 TLL2	1.12e-03	6	164	2	PF01400
Domain	Sec23/24_trunk_dom	SEC24A SEC24B	1.12e-03	6	164	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24A SEC24B	1.12e-03	6	164	2	IPR006895
Domain	-	TPTE DUSP1 TPTE2 MTMR3 TNS3	1.31e-03	92	164	5	3.90.190.10
Domain	PLA2_B	PLA2G4D PLA2G4C	1.56e-03	7	164	2	PF01735
Domain	PLA2C	PLA2G4D PLA2G4C	1.56e-03	7	164	2	PS51210
Domain	Rab_bind	RGPD4 RGPD3	1.56e-03	7	164	2	PF16704
Domain	LysoPLipase_cat_dom	PLA2G4D PLA2G4C	1.56e-03	7	164	2	IPR002642
Domain	GCC2_Rab_bind	RGPD4 RGPD3	1.56e-03	7	164	2	IPR032023
Domain	PLAc	PLA2G4D PLA2G4C	1.56e-03	7	164	2	SM00022
Domain	Prot-tyrosine_phosphatase-like	TPTE DUSP1 TPTE2 MTMR3 TNS3	1.81e-03	99	164	5	IPR029021
Domain	LisH	TBL1Y TBL1XR1 TBL1X	1.85e-03	28	164	3	IPR006594
Domain	LisH	TBL1Y TBL1XR1 TBL1X	1.85e-03	28	164	3	SM00667
Domain	LISH	TBL1Y TBL1XR1 TBL1X	1.85e-03	28	164	3	PS50896
Domain	EGF_1	TPO COMP CUBN BMP1 THBS3 TLL2 CNTNAP2 TENM1	1.90e-03	255	164	8	PS00022
Domain	DWB	SMAD1 SMAD5	2.07e-03	8	164	2	SM00524
Domain	MH2	SMAD1 SMAD5	2.07e-03	8	164	2	PS51076
Domain	MH1	SMAD1 SMAD5	2.07e-03	8	164	2	PS51075
Domain	-	SMAD1 SMAD5	2.07e-03	8	164	2	3.90.520.10
Domain	MAD_homology_MH1	SMAD1 SMAD5	2.07e-03	8	164	2	IPR013019
Domain	Dwarfin	SMAD1 SMAD5	2.07e-03	8	164	2	IPR013790
Domain	MH2	SMAD1 SMAD5	2.07e-03	8	164	2	PF03166
Domain	SMAD_dom_Dwarfin-type	SMAD1 SMAD5	2.07e-03	8	164	2	IPR001132
Domain	EGF-type_Asp/Asn_hydroxyl_site	TPO NID2 CUBN BMP1 TLL2	2.44e-03	106	164	5	IPR000152
Domain	Mit_carrier	SLC25A16 SLC25A12 SLC25A13	2.73e-03	32	164	3	IPR002067
Domain	-	SEMA3F TBL1Y TBL1XR1 WDR38 LLGL1 GNB4 HERC1 TBL1X SEMA3E	2.77e-03	333	164	9	2.130.10.10
Domain	An_peroxidase	TPO PXDNL	3.29e-03	10	164	2	PF03098
Domain	Haem_peroxidase_animal	TPO PXDNL	3.29e-03	10	164	2	IPR019791
Domain	Haem_peroxidase	TPO PXDNL	3.29e-03	10	164	2	IPR010255
Domain	PEROXIDASE_3	TPO PXDNL	3.29e-03	10	164	2	PS50292
Domain	-	TPO PXDNL	3.29e-03	10	164	2	1.10.640.10
Domain	-	RGPD4 RGPD3	3.29e-03	10	164	2	1.10.220.60
Domain	Tyr_Pase_AS	TPTE DUSP1 TPTE2 MTMR3	3.90e-03	73	164	4	IPR016130
Domain	Grip	RGPD4 RGPD3	4.00e-03	11	164	2	SM00755
Domain	GRIP	RGPD4 RGPD3	4.00e-03	11	164	2	PF01465
Domain	Ran_BP1	RGPD4 RGPD3	4.77e-03	12	164	2	PF00638
Domain	MAD_homology1_Dwarfin-type	SMAD1 SMAD5	4.77e-03	12	164	2	IPR003619
Domain	DWA	SMAD1 SMAD5	4.77e-03	12	164	2	SM00523
Domain	EGF_dom	NID2 CUBN	4.77e-03	12	164	2	IPR024731
Domain	RANBD1	RGPD4 RGPD3	4.77e-03	12	164	2	PS50196
Domain	EGF_3	NID2 CUBN	4.77e-03	12	164	2	PF12947
Domain	GRIP_dom	RGPD4 RGPD3	4.77e-03	12	164	2	IPR000237
Domain	GRIP	RGPD4 RGPD3	4.77e-03	12	164	2	PS50913
Domain	MH1	SMAD1 SMAD5	4.77e-03	12	164	2	PF03165
Domain	WD40_repeat_dom	TBL1Y TBL1XR1 WDR38 SF3B3 LLGL1 GNB4 HERC1 TBL1X	4.80e-03	297	164	8	IPR017986
Domain	EGF	NID2 CUBN BMP1 TLL2 CNTNAP2	5.11e-03	126	164	5	PF00008
Domain	Dual-sp_phosphatase_cat-dom	TPTE DUSP1 TPTE2	5.55e-03	41	164	3	IPR000340
Domain	DSPc	TPTE DUSP1 TPTE2	5.55e-03	41	164	3	PF00782
Pubmed	BMP9 promotes cutaneous wound healing by activating Smad1/5 signaling pathways and cytoskeleton remodeling.	GDF2 SMAD1 SMAD5	1.11e-07	3	168	3	33463047
Pubmed	Interaction of TGFβ and BMP signaling pathways during chondrogenesis.	BMP1 SMAD1 SMAD5	4.41e-07	4	168	3	21297990
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RGPD4 TBL1Y TBL1XR1 KMT2C RGPD3 ZNF281 CNOT1 TBL1X	6.00e-07	146	168	8	23892456
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 OR8G2P OR10G6 OR10J5 OR2V2 OR4C5	9.15e-07	340	168	11	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 OR8G2P OR10G6 OR10J5 OR2V2 OR4C5	9.15e-07	340	168	11	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 OR8G2P OR10G6 OR10J5 OR2V2 OR4C5	9.96e-07	343	168	11	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5M1 OR6N2 OR5B2 OR11H7 OR2V1 OR2J1 OR8G2P OR10G6 OR10J5 OR2V2 OR4C5	1.08e-06	346	168	11	14611657
Pubmed	Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.	TBL1Y TBL1XR1 TBL1X	1.10e-06	5	168	3	21459324
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 EYA4 ZNF148 GAPDH TBL1XR1 KMT2C MCM3AP KDM2B ZNF281 ZMYM3 TBL1X	1.25e-06	351	168	11	38297188
Pubmed	Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors.	WT1 BMP1 SMAD1 SMAD5	1.52e-06	18	168	4	19914233
Pubmed	Human transcription factor protein interaction networks.	TRERF1 EYA4 ZNF148 TBL1Y IARS1 RBM10 SEC24A TBL1XR1 NPM3 KMT2C SLC25A13 SEC24B SLC25A10 KDM2B MLLT1 GNB4 HERC1 ZNF281 CNOT1 ZMYM3 SMAD5 TBL1X	1.67e-06	1429	168	22	35140242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP104 INPP5E TIAM2 PPP4R3B KMT2C KLHL9 SF3B3 AP5Z1 CNTNAP2 KDM2B EIF2AK4 CNOT1 SEMA3E	2.00e-06	529	168	13	14621295
Pubmed	Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.	TBL1Y TBL1XR1 TBL1X	2.19e-06	6	168	3	28348241
Pubmed	Hypoxia and Reactive Oxygen Species Homeostasis in Mesenchymal Progenitor Cells Define a Molecular Mechanism for Fracture Nonunion.	HIF1A SMAD1 SMAD5	2.19e-06	6	168	3	27250101
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TANC2 SEC24A MAP3K20 TBL1XR1 CNTROB HIF1AN TRAK1 CDC42EP1 MCM3AP SEC24B AGFG1 GNB4 DHX35 CNOT1 SMAD1 TNS3 SMAD5 TBL1X	3.14e-06	1038	168	18	26673895
Pubmed	Fibroblast growth factor 2 inhibits bone morphogenetic protein 9-induced osteogenic differentiation of mesenchymal stem cells by repressing Smads signaling and subsequently reducing Smads dependent up-regulation of ALK1 and ALK2.	GDF2 SMAD1 SMAD5	3.82e-06	7	168	3	23680673
Pubmed	The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.	TBL1Y TBL1XR1 TBL1X	3.82e-06	7	168	3	15695367
Pubmed	Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.	TBL1Y TBL1XR1 TBL1X	3.82e-06	7	168	3	27646874
Pubmed	The mitochondrial transporter family SLC25: identification, properties and physiopathology.	SLC25A33 SLC25A16 SLC25A12 SLC25A13 SLC25A10	5.89e-06	53	168	5	23266187
Pubmed	A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.	TBL1Y TBL1XR1 TBL1X	6.09e-06	8	168	3	16127449
Pubmed	Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.	TBL1Y TBL1XR1 TBL1X	6.09e-06	8	168	3	23770565
Pubmed	Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability.	BMP1 SMAD1 SMAD5	9.10e-06	9	168	3	16087734
Pubmed	A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.	TBL1Y TBL1XR1 TBL1X	1.30e-05	10	168	3	14980219
Pubmed	The human olfactory receptor gene family.	OR10H5 OR5M1 OR6N2 OR5B2 OR11H7 OR2J1 OR8G2P OR10G6 OR4S1 OR10J5 OR2V2 OR4C5	1.40e-05	541	168	12	14983052
Pubmed	Endofin acts as a Smad anchor for receptor activation in BMP signaling.	ZFYVE9 SMAD1 SMAD5	1.78e-05	11	168	3	17356069
Pubmed	Msx1 deficiency interacts with hypoxia and induces a morphogenetic regulation during mouse lip development.	HIF1A SMAD1 SMAD5	1.78e-05	11	168	3	32467233
Pubmed	Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.	SLC25A12 SLC25A13	2.32e-05	2	168	2	25410934
Pubmed	Application of a global proteomic approach to archival precursor lesions: deleted in malignant brain tumors 1 and tissue transglutaminase 2 are upregulated in pancreatic cancer precursors.	TGM2 DMBT1	2.32e-05	2	168	2	18849643
Pubmed	Diagnostic role of markers dipeptidyl peptidase IV and thyroid peroxidase in thyroid tumors.	TPO DPP4	2.32e-05	2	168	2	12820316
Pubmed	Suppression of the dual-specificity phosphatase MKP-1 enhances HIF-1 trans-activation and increases expression of EPO.	HIF1A DUSP1	2.32e-05	2	168	2	14680833
Pubmed	Two new cases of interstitial 7q35q36.1 deletion including CNTNAP2 and KMT2C.	KMT2C CNTNAP2	2.32e-05	2	168	2	34582124
Pubmed	TBL1X: At the crossroads of transcriptional and posttranscriptional regulation.	TBL1XR1 TBL1X	2.32e-05	2	168	2	36206873
Pubmed	BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells.	SMAD1 SMAD5	2.32e-05	2	168	2	26711875
Pubmed	MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity.	KMT2C TNS3	2.32e-05	2	168	2	33824309
Pubmed	The transcriptional role of Smads and FAST (FoxH1) in TGFbeta and activin signalling.	SMAD1 SMAD5	2.32e-05	2	168	2	11451566
Pubmed	Factor inhibiting HIF (FIH) recognizes distinct molecular features within hypoxia-inducible factor-α (HIF-α) versus ankyrin repeat substrates.	HIF1A HIF1AN	2.32e-05	2	168	2	22270367
Pubmed	DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis.	DISC1 NDEL1	2.32e-05	2	168	2	29103808
Pubmed	Featured Article: Hypoxia-inducible factor-1α dependent nuclear entry of factor inhibiting HIF-1.	HIF1A HIF1AN	2.32e-05	2	168	2	25687434
Pubmed	NDEL1 was decreased in the CA3 region but increased in the hippocampal blood vessel network during the spontaneous seizure period after pilocarpine-induced status epilepticus.	DISC1 NDEL1	2.32e-05	2	168	2	24680936
Pubmed	Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).	HIF1A HIF1AN	2.32e-05	2	168	2	19401150
Pubmed	Erythropoietin receptors in endometrial carcinoma as related to HIF1{alpha} and VEGF expression.	EPOR HIF1A	2.32e-05	2	168	2	19779103
Pubmed	FIH-1-modulated HIF-1α C-TAD promotes acute kidney injury to chronic kidney disease progression via regulating KLF5 signaling.	HIF1A HIF1AN	2.32e-05	2	168	2	33658705
Pubmed	Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain.	DISC1 NDEL1	2.32e-05	2	168	2	17825401
Pubmed	Infantile hemangioma-derived stem cells and endothelial cells are inhibited by class 3 semaphorins.	SEMA3F SEMA3E	2.32e-05	2	168	2	26086095
Pubmed	Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression.	HIF1A HIF1AN	2.32e-05	2	168	2	21732131
Pubmed	X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats.	TBL1Y TBL1X	2.32e-05	2	168	2	10330347
Pubmed	Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly.	DISC1 NDEL1	2.32e-05	2	168	2	21998303
Pubmed	Expanded phenotypes and outcomes among 256 LGI1/CASPR2-IgG-positive patients.	LLGL1 CNTNAP2	2.32e-05	2	168	2	28628235
Pubmed	Transglutaminase 2-dependent deamidation of glyceraldehyde-3-phosphate dehydrogenase promotes trophoblastic cell fusion.	GAPDH TGM2	2.32e-05	2	168	2	24375405
Pubmed	BMP-SMAD1/5 Signaling Regulates Retinal Vascular Development.	SMAD1 SMAD5	2.32e-05	2	168	2	32210087
Pubmed	Polarized PtdIns(4,5)P2 distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility.	TPTE TPTE2	2.32e-05	2	168	2	31776261
Pubmed	Zfp281 and Zfp148 control CD4+ T cell thymic development and TH2 functions.	ZNF148 ZNF281	2.32e-05	2	168	2	37948511
Pubmed	Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase.	GAPDH BMP1	2.32e-05	2	168	2	8174772
Pubmed	BMP receptor-integrin interaction mediates responses of vascular endothelial Smad1/5 and proliferation to disturbed flow.	SMAD1 SMAD5	2.32e-05	2	168	2	23387849
Pubmed	Ca2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttle.	SLC25A12 SLC25A13	2.32e-05	2	168	2	17213189
Pubmed	Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.	SMAD1 SMAD5	2.32e-05	2	168	2	8799132
Pubmed	Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease.	DISC1 NDEL1	2.32e-05	2	168	2	18400883
Pubmed	DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.	DISC1 NDEL1	2.32e-05	2	168	2	17035248
Pubmed	BMP signaling dynamics in embryonic orofacial tissue.	SMAD1 SMAD5	2.32e-05	2	168	2	18446813
Pubmed	Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization.	SMAD1 SMAD5	2.32e-05	2	168	2	21723296
Pubmed	Regulation of the levels of Smad1 and Smad5 in MC3T3-E1 cells by Icariine in vitro.	SMAD1 SMAD5	2.32e-05	2	168	2	24297369
Pubmed	The Combination of Natural Molecules Naringenin, Hesperetin, Curcumin, Polydatin and Quercetin Synergistically Decreases SEMA3E Expression Levels and DPPIV Activity in In Vitro Models of Insulin Resistance.	DPP4 SEMA3E	2.32e-05	2	168	2	37175783
Pubmed	Presynaptic Excitation via GABAB Receptors in Habenula Cholinergic Neurons Regulates Fear Memory Expression.	CACNA1E GABBR1	2.32e-05	2	168	2	27426949
Pubmed	Mechanical stress affects the osteogenic differentiation of human ligamentum flavum cells via the BMP‑Smad1 signaling pathway.	BMP1 SMAD1	2.32e-05	2	168	2	28944874
Pubmed	Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1.	DISC1 NDEL1	2.32e-05	2	168	2	15728732
Pubmed	SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth.	TBL1XR1 TBL1X	2.32e-05	2	168	2	27129164
Pubmed	Effects of representative point mutations on dynamic behavior of the DISC1-Ndel1 complex: a molecular dynamics study.	DISC1 NDEL1	2.32e-05	2	168	2	36858606
Pubmed	Exogenous aralar/slc25a12 can replace citrin/slc25a13 as malate aspartate shuttle component in liver.	SLC25A12 SLC25A13	2.32e-05	2	168	2	36967723
Pubmed	Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor.	HIF1A HIF1AN	2.32e-05	2	168	2	14734545
Pubmed	AGC1/2, the mitochondrial aspartate-glutamate carriers.	SLC25A12 SLC25A13	2.32e-05	2	168	2	27132995
Pubmed	Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates.	HIF1A HIF1AN	2.32e-05	2	168	2	17135241
Pubmed	Expression of the aspartate/glutamate mitochondrial carriers aralar1 and citrin during development and in adult rat tissues.	SLC25A12 SLC25A13	2.32e-05	2	168	2	12084073
Pubmed	Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.	HIF1A HIF1AN	2.32e-05	2	168	2	12432100
Pubmed	Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha.	HIF1A HIF1AN	2.32e-05	2	168	2	12446723
Pubmed	The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein.	SLC25A12 SLC25A13	2.32e-05	2	168	2	10369257
Pubmed	Transducin β-like 1, X-linked and nuclear receptor co-repressor cooperatively augment the ligand-independent stimulation of TRH and TSHβ gene promoters by thyroid hormone receptors.	TBL1Y TBL1X	2.32e-05	2	168	2	29794369
Pubmed	The role of factor inhibiting HIF (FIH-1) in inhibiting HIF-1 transcriptional activity in glioblastoma multiforme.	HIF1A HIF1AN	2.32e-05	2	168	2	24465898
Pubmed	A novel human TPIP splice-variant (TPIP-C2) mRNA, expressed in human and mouse tissues, strongly inhibits cell growth in HeLa cells.	TPTE TPTE2	2.32e-05	2	168	2	22164291
Pubmed	Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis.	WT1 SMAD1 SMAD5	2.36e-05	12	168	3	32698004
Pubmed	Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.	WT1 SMAD1 SMAD5	2.36e-05	12	168	3	17460146
Pubmed	Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.	GDF2 TMEM100 SMAD1 SMAD5	3.41e-05	38	168	4	22783020
Pubmed	Bmp in podocytes is essential for normal glomerular capillary formation.	WT1 SMAD1 SMAD5	3.88e-05	14	168	3	18272846
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	CEP104 TPTE DPP4 EYA4 RBM10 DUSP1 TPTE2 MTMR3 HERC1 TNS3	4.10e-05	420	168	10	28065597
Pubmed	WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors.	WT1 SMAD1 SMAD5	4.83e-05	15	168	3	25031030
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	TRERF1 TPTE DISC1 WT1 ZRANB3 NPM3 AEBP1 AGFG1 SMAD1 SLC35A5	4.99e-05	430	168	10	35044719
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TPTE EYA4 SEC24A DUSP1 TPTE2 CNTROB CDC42EP1 PPP4R3B ZFYVE9 SEC24B MTMR3 GNB4 EIF2AK4 HERC1 CNOT1 TNS3	5.34e-05	1049	168	16	27880917
Pubmed	Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos.	TMEM100 SMAD1 SMAD5	5.92e-05	16	168	3	25318679
Pubmed	Spatial and temporal expression of molecular markers and cell signals during normal development of the mouse patellar tendon.	COMP SMAD1 SMAD5	5.92e-05	16	168	3	21939397
Pubmed	Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney.	WT1 SMAD1 SMAD5	5.92e-05	16	168	3	35877077
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	RGPD4 TPTE IARS1 TPTE2 GPATCH1 SF3B3 CNOT1	6.03e-05	202	168	7	24639526
Pubmed	EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.	ZNF148 KDM2B MLLT1 ZNF281	6.13e-05	44	168	4	27505670
Pubmed	Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.	TRERF1 TBL1XR1 ZMYM3 TBL1X	6.71e-05	45	168	4	21258344
Pubmed	Role of class 3 semaphorins in the development and maturation of the septohippocampal pathway.	SEMA3F SEMA3E	6.94e-05	3	168	2	15386596
Pubmed	Lysyl oxidase inhibits BMP9-induced osteoblastic differentiation through reducing Wnt/β-catenin via HIF-1a repression in 3T3-L1 cells.	HIF1A GDF2	6.94e-05	3	168	2	38031108
Pubmed	Study on the role of Hsa-miR-31-5p in hypertrophic scar formation and the mechanism.	HIF1A HIF1AN	6.94e-05	3	168	2	29056521
Pubmed	Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha.	HIF1A HIF1AN	6.94e-05	3	168	2	11959990
Pubmed	Non-canonical cyclic AMP SMAD1/5/8 signalling in human granulosa cells.	SMAD1 SMAD5	6.94e-05	3	168	2	30953749
Pubmed	Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation.	SMAD1 SMAD5	6.94e-05	3	168	2	32720893
Pubmed	Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively.	HIF1A HIF1AN	6.94e-05	3	168	2	30333145
Pubmed	Tbl1 promotes Wnt-β-catenin signaling-induced degradation of the Tcf7l1 protein in mouse embryonic stem cells.	TBL1Y TBL1X	6.94e-05	3	168	2	38639717
GeneFamily	Solute carriers	SLC6A18 SLC25A33 SLC7A7 SLC25A16 SLC35F4 SLC5A3 SLC2A10 SLC8A3 SLC25A12 SLC12A9 SLC17A9 SLC20A2 SLC25A13 SLC25A10 SLC16A11 SLC38A11 SLC35A5	1.71e-09	395	124	17	752
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	TPTE TPTE2 TNS3	1.72e-05	8	124	3	837
GeneFamily	Immunoglobulin like domain containing\|Adhesion G protein-coupled receptors, subfamily A	ADGRA1 ADGRA3	1.39e-04	3	124	2	911
GeneFamily	C2 tensin-type domain containing\|PTEN protein phosphatases\|Phosphoinositide phosphatases	TPTE TPTE2	4.60e-04	5	124	2	902
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP1 TLL2	6.87e-04	6	124	2	894
GeneFamily	SMAD family	SMAD1 SMAD5	1.27e-03	8	124	2	750
GeneFamily	WD repeat domain containing	TBL1Y TBL1XR1 WDR38 LLGL1 GNB4 HERC1 TBL1X	2.21e-03	262	124	7	362
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	DPP4 ATG2B CUBN CD160 SLC25A10 PTCD2 LY75	4.00e-06	172	167	7	1215f61f115b042f84721b64c2ed1f48081535f1
ToppCell	facs-Kidney-nan-24m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM158 WT1 THBS3 AEBP1 PPIP5K1 ADGRA1 TMEM100	5.39e-06	180	167	7	f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 SYNE1 DUSP1 WT1 SLC35F4 TLL2 UNC5C	5.59e-06	181	167	7	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 SYNE1 DUSP1 WT1 SLC35F4 TLL2 UNC5C	5.59e-06	181	167	7	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 SYNE1 WT1 SLC35F4 AEBP1 TLL2 UNC5C	6.45e-06	185	167	7	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 SYNE1 WT1 SLC35F4 AEBP1 TLL2 UNC5C	6.45e-06	185	167	7	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 SYNE1 WT1 SLC35F4 AEBP1 UNC5C	2.74e-05	156	167	6	dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 SYNE1 WT1 SLC35F4 AEBP1 UNC5C	2.74e-05	156	167	6	abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OR5B2 SEC24A TPTE2 SLC17A9 EIF2AK4 FCRL5	3.39e-05	162	167	6	8ed9149ff53b285591354057055d072b203a47c8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OR5B2 SEC24A TPTE2 SLC17A9 EIF2AK4 FCRL5	3.39e-05	162	167	6	7a05b05a33e1309fb5c0a8171db105ae68491815
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANKRD29 EYA4 MAP3K20 KCNIP2 HHATL ADGRA3	3.51e-05	163	167	6	db6b7ce6f7221bb73c5e650ac51cdd5d7ef00675
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1E CATSPERD CUBN SLC7A7 CSMD3 CNTNAP2	4.02e-05	167	167	6	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPO CUBN CSMD3 PLA2G4C AEBP1 CNTNAP2	4.29e-05	169	167	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	NEU4 SLC7A7 SLC12A9 GNB4 SLC16A11 EIF2AK4	4.89e-05	173	167	6	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPO ANKRD29 CUBN CSMD3 PLA2G4C AEBP1	4.89e-05	173	167	6	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPO ANKRD29 CUBN CSMD3 PLA2G4C AEBP1	4.89e-05	173	167	6	649b08a409095592cccf31883be69c754411280d
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Nnat_(iSPN)\|Striatum / BrainAtlas - Mouse McCarroll V32	TPO CATSPERD CD163L1 BTNL9	5.01e-05	54	167	4	d21611ae38d34d62f855fa3797eb37a5d287a4a5
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Nnat_(iSPN)-\|Striatum / BrainAtlas - Mouse McCarroll V32	TPO CATSPERD CD163L1 BTNL9	5.01e-05	54	167	4	20309afadc500f1485e86c62d8d38168c9253539
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 SYNE1 WT1 PCDHB3 PIEZO2 UNC5C	5.21e-05	175	167	6	12f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell	facs-Skin-nan-24m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNIP2 PIEZO2 PLA2G4C UNC5C GNB4 TNS3	5.21e-05	175	167	6	f1166b567bca80dac3abe90c3dc544c831006640
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	TPO SEMA3F SYNE1 PLA2G4C BTNL9 TMEM100	6.28e-05	181	167	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	Cerebellum-Macroglia\|Cerebellum / BrainAtlas - Mouse McCarroll V32	IGSF11 HHATL THBS3 KCNJ16 PLP1 TNS3	6.88e-05	184	167	6	91b047a01d2cad231308279ca37fa699630f7864
ToppCell	droplet-Kidney-nan-18m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP1 IGSF11 CUBN SLC7A7 TGM2 KCNJ16	6.88e-05	184	167	6	e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EYA4 MAP3K20 PXDNL CNTNAP2 PLP1 SEMA3E	7.30e-05	186	167	6	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 NID2 HIF1A TENM1 SLC38A11 TNS3	7.52e-05	187	167	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAPDH IGSF11 SLC7A7 UNC5C SLC25A10 PLP1	7.75e-05	188	167	6	b483b4629695764568bcbd1d527d614824147783
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAPDH IGSF11 SLC7A7 UNC5C SLC25A10 PLP1	7.75e-05	188	167	6	c1f64311ff05093b2f4f672e33f5f75e3bc8a8db
ToppCell	Non-neuronal-Non-dividing-OPC-OPC\|World / Primary Cells by Cluster	NEU4 DISC1 KCNJ16 TMEM100 PLP1 TNS3	7.98e-05	189	167	6	ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PLPP5 DRAM2 CNTNAP2 GNB4 SLC38A11 FCRL5	7.98e-05	189	167	6	e2bb5900d210386b7b74938e7a3636d0c7ba1bcf
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DPP4 NID2 TRAK1 CDC42EP1 TGM2 PXDNL	7.98e-05	189	167	6	9c2492c38f27e4c699b40680652e4c64911cce52
ToppCell	Non-neuronal-Non-dividing-OPC\|World / Primary Cells by Cluster	NEU4 DISC1 KCNJ16 TMEM100 PLP1 TNS3	7.98e-05	189	167	6	13848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 WT1 TGM2 ALX1 AEBP1 UNC5C	7.98e-05	189	167	6	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	Non-neuronal-Non-dividing-OPC-OPC-30\|World / Primary Cells by Cluster	NEU4 DISC1 KCNJ16 TMEM100 PLP1 TNS3	7.98e-05	189	167	6	313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 WT1 PIEZO2 ALX1 AEBP1 UNC5C	8.45e-05	191	167	6	1caf726bd07fdca389e678fc16304a6ef1790423
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLPP5 DRAM2 CNTNAP2 SLC38A11 FCRL5 BTNL9	8.45e-05	191	167	6	07b03739db24c7d834300de63ef1847724cba684
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 WT1 PIEZO2 ALX1 AEBP1 UNC5C	8.45e-05	191	167	6	3d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 WT1 PIEZO2 ALX1 AEBP1 UNC5C	8.70e-05	192	167	6	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 WT1 PIEZO2 ALX1 AEBP1 UNC5C	8.70e-05	192	167	6	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLPP5 DRAM2 CNTNAP2 SLC38A11 FCRL5 BTNL9	8.70e-05	192	167	6	ee309564ac6136c1dc314d5cd3603687ee2266f2
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP4 BMP1 THBS3 AEBP1 TMEM100 SEMA3E	9.21e-05	194	167	6	7b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NID2 PIEZO2 PLA2G4C AEBP1 UNC5C	9.21e-05	194	167	6	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NID2 PIEZO2 PLA2G4C AEBP1 UNC5C	9.21e-05	194	167	6	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 TMEM158 THBS3 AEBP1 TMEM100 SEMA3E	9.21e-05	194	167	6	0e315c63407fa00643722a7d6138b1502f79b10d
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 TMEM158 THBS3 AEBP1 TMEM100 SEMA3E	9.21e-05	194	167	6	c2990d6eda3954dc01913bf3910df79f06e0010a
ToppCell	control-immature_Neutrophil\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRERF1 TANC2 TRIM34 TLR5 TNS3 TBL1X	9.74e-05	196	167	6	e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	TPO SEMA3F SYNE1 PLA2G4C BTNL9 TMEM100	9.74e-05	196	167	6	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 EYA4 SYNE1 MAP3K20 AEBP1 TNS3	1.00e-04	197	167	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 EYA4 SYNE1 MAP3K20 AEBP1 TNS3	1.00e-04	197	167	6	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 HIF1A COMP TIAM2 TGM2 UNC5C	1.00e-04	197	167	6	8786125b669d5d0b15e12df0ade6b319f09f7333
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CEP104 SLC7A7 ADPRH CLN3 KCNJ16 GNB4	1.03e-04	198	167	6	9a77038e5db0ea757fd7ebcab294785b166ddc12
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID2 HIF1A COMP TIAM2 TGM2 UNC5C	1.03e-04	198	167	6	3575620db5aeaeb0bdcd7a8ff65c43abd3fa13e4
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KCNIP2 HHATL SLC35F4 PIEZO2 CNTNAP2 TENM1	1.09e-04	200	167	6	4a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COMP SYNE1 PIEZO2 ALX1 UNC5C ADGRA3	1.09e-04	200	167	6	b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COMP SYNE1 PIEZO2 ALX1 UNC5C ADGRA3	1.09e-04	200	167	6	f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KCNIP2 HHATL SLC35F4 PIEZO2 CNTNAP2 TENM1	1.09e-04	200	167	6	fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	KCNIP2 HHATL SLC35F4 PIEZO2 CNTNAP2 TENM1	1.09e-04	200	167	6	c6eda342ea0cb37d71d89dbb8d11e819e0745172
Drug	Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; HL60; HT_HG-U133A	KANSL1L RHBDF1 DUSP1 HIF1AN BMP1 SLC20A2 CLN3 AGFG1 SMAD1 TBL1X	1.75e-06	196	165	10	2424_DN
Drug	Trolox [53188-07-1]; Down 200; 16uM; PC3; HT_HG-U133A	SEMA3F EPOR WT1 HIF1AN PPP4R3B TGM2 THBS3 ZFYVE9 SLC12A9 AP5Z1	1.91e-06	198	165	10	7304_DN
Drug	5-methoxypsoralen	UGT1A1 SMAD1 SMAD5	1.28e-05	7	165	3	ctd:C022909
Drug	Tracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; PC3; HT_HG-U133A	SYNE1 MAP3K20 ACOX2 PPP4R3B BMP1 THBS3 RAB28 SF3B3 SLC12A9	1.36e-05	196	165	9	6619_DN
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	DPP4 GPATCH1 MAP3K20 TGOLN2 SLC2A10 THBS3 RAB28 DHX35 DMBT1	1.42e-05	197	165	9	2075_UP
Drug	Halofantrine hydrochloride [36167-63-2]; Down 200; 7.4uM; MCF7; HT_HG-U133A	EPOR DISC1 TRAK1 THBS3 RAB28 KLHL9 SF3B3 SLC12A9 KLHL36	1.42e-05	197	165	9	6509_DN
Drug	Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SEMA3F EPOR TBL1Y DISC1 TRAK1 BMP1 THBS3 DHX35 SMAD1	1.48e-05	198	165	9	2815_DN
Drug	Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A	SEMA3F KANSL1L DPP4 NPM3 TRAK1 THBS3 LLGL1 SLC12A9 AP5Z1	1.54e-05	199	165	9	3345_DN
Drug	Thiocolchicoside [602-41-5]; Down 200; 7uM; PC3; HT_HG-U133A	EPOR EYA4 GPATCH1 MAP3K20 HIF1AN TRAK1 PPP4R3B RAB28 AGFG1	1.54e-05	199	165	9	5095_DN
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A	SEMA3F MAP3K20 TRAK1 BMP1 THBS3 KLHL36 SLC20A2 CNTNAP2 MTMR3	1.54e-05	199	165	9	4543_DN
Drug	LDN 193189	GDF2 SMAD1 SMAD5	2.04e-05	8	165	3	ctd:C554430
Disease	sensory system disease (implicated_via_orthology)	TBL1Y TBL1XR1 TBL1X	1.56e-07	3	160	3	DOID:0050155 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	TRERF1 ANKRD29 EPOR TPTE NID2 HIF1A SYNE1 WT1 CUBN SLC7A7 TMEM25 SLC2A10 BMP1 TGM2 THBS3 SLC8A3 LLGL1 MTMR3 TENM1 FCRL5 ZNF281	3.95e-07	1074	160	21	C0006142
Disease	common bile duct disease (implicated_via_orthology)	SLC25A12 SLC25A13	2.92e-05	2	160	2	DOID:4137 (implicated_via_orthology)
Disease	Asperger syndrome (is_implicated_in)	DISC1 SLC25A12	2.92e-05	2	160	2	DOID:0050432 (is_implicated_in)
Disease	2-oxo-hept-3-ene-1,7-dioate hydratase activity	GDF2 EIF2AK4 SMAD1	5.45e-05	14	160	3	C1150929
Disease	citrullinemia (implicated_via_orthology)	SLC25A12 SLC25A13	8.73e-05	3	160	2	DOID:9273 (implicated_via_orthology)
Disease	Familial primary pulmonary hypertension	GDF2 EIF2AK4 SMAD1	1.01e-04	17	160	3	C0340543
Disease	Colorectal Carcinoma	EYA4 GALNS GAPDH SYNE1 RBM10 CUBN CSMD3 TGM2 KMT2C FCN2 MCM3AP TENM1 GNB4	1.25e-04	702	160	13	C0009402
Disease	urinary microalbumin measurement	CUBN SLC25A16 CNTNAP2	1.67e-04	20	160	3	EFO_0010967
Disease	intrahepatic cholestasis (implicated_via_orthology)	SLC25A12 SLC25A13	1.74e-04	4	160	2	DOID:1852 (implicated_via_orthology)
Disease	protein s100-a9 measurement	OR10J5 MPTX1	2.89e-04	5	160	2	EFO_0020687
Disease	palmitoleic acid measurement	HIF1AN MLLT1	6.03e-04	7	160	2	EFO_0007973
Disease	Hyperkinesia	DISC1 CNTNAP2 GABBR1	6.91e-04	32	160	3	C3887506
Disease	Hyperkinesia, Generalized	DISC1 CNTNAP2 GABBR1	6.91e-04	32	160	3	C0751217
Disease	visual epilepsy (implicated_via_orthology)	CNTNAP2 PLP1 GABBR1	8.28e-04	34	160	3	DOID:11832 (implicated_via_orthology)
Disease	Erythrocytosis familial, 1	EPOR HIF1A	1.03e-03	9	160	2	C4551637
Disease	Idiopathic pulmonary hypertension	EIF2AK4 SMAD1	1.03e-03	9	160	2	C0152171
Disease	Tendinopathy	CACNA1E CNTNAP2	1.03e-03	9	160	2	EFO_1001434
Disease	Pulmonary Hypertension	HIF1A GDF2 EIF2AK4	1.33e-03	40	160	3	C0020542
Disease	autistic disorder (is_implicated_in)	DISC1 SLC25A12 CNTNAP2	1.54e-03	42	160	3	DOID:12849 (is_implicated_in)
Disease	Amino Acid Metabolism, Inherited Disorders	SLC7A7 EIF2AK4	2.19e-03	13	160	2	C0750905
Disease	juvenile polyposis syndrome (implicated_via_orthology)	SMAD1 SMAD5	2.19e-03	13	160	2	DOID:0050787 (implicated_via_orthology)
Disease	Amino Acid Metabolism, Inborn Errors	SLC7A7 EIF2AK4	2.19e-03	13	160	2	C0002514
Disease	Mammary Carcinoma, Human	TRERF1 EPOR HIF1A SYNE1 WT1 TMEM25 SLC2A10 TGM2 LLGL1	2.35e-03	525	160	9	C4704874
Disease	Mammary Neoplasms, Human	TRERF1 EPOR HIF1A SYNE1 WT1 TMEM25 SLC2A10 TGM2 LLGL1	2.35e-03	525	160	9	C1257931
Disease	Mammary Neoplasms	TRERF1 EPOR HIF1A SYNE1 WT1 TMEM25 SLC2A10 TGM2 LLGL1	2.42e-03	527	160	9	C1458155
Disease	Breast Carcinoma	TRERF1 EPOR HIF1A SYNE1 WT1 TMEM25 SLC2A10 TGM2 LLGL1	2.77e-03	538	160	9	C0678222
Disease	hepatic encephalopathy (biomarker_via_orthology)	EPOR HIF1A	2.93e-03	15	160	2	DOID:13413 (biomarker_via_orthology)
Disease	Autistic Disorder	DISC1 CSMD3 TBL1XR1 SLC25A12 CNTNAP2 GABBR1	3.09e-03	261	160	6	C0004352
Disease	Idiopathic pulmonary arterial hypertension	EIF2AK4 SMAD1	3.34e-03	16	160	2	C3203102
Disease	major depressive disorder (is_marker_for)	DISC1 DUSP1	3.77e-03	17	160	2	DOID:1470 (is_marker_for)
Disease	major depressive disorder (is_implicated_in)	DISC1 CNTNAP2	3.77e-03	17	160	2	DOID:1470 (is_implicated_in)
Disease	Bipolar Disorder	TPO HIF1A DISC1 SYNE1 SLC5A3 TGM2 TLL2 CNTNAP2	4.64e-03	477	160	8	C0005586
Disease	type 1 diabetes mellitus (biomarker_via_orthology)	DUSP1 UGT1A1	4.70e-03	19	160	2	DOID:9744 (biomarker_via_orthology)
Disease	Alzheimer disease, polygenic risk score	SEMA3F CACNA1E MAP3K20 SF3B3 CNTNAP2 MTMR3 PTCD2 LY75 GABBR1	4.83e-03	586	160	9	EFO_0030082, MONDO_0004975
Disease	Cocaine Abuse	PLP1 GABBR1 SMAD1 SMAD5	5.13e-03	127	160	4	C0009171
Disease	diet measurement, body mass index	TBL1XR1 CNTNAP2	5.21e-03	20	160	2	EFO_0004340, EFO_0008111
Disease	Sarcomatoid Renal Cell Carcinoma	CSMD3 SLC5A3 TGM2 UNC5C	5.28e-03	128	160	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	CSMD3 SLC5A3 TGM2 UNC5C	5.28e-03	128	160	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	CSMD3 SLC5A3 TGM2 UNC5C	5.28e-03	128	160	4	C1266044
Disease	Papillary Renal Cell Carcinoma	CSMD3 SLC5A3 TGM2 UNC5C	5.28e-03	128	160	4	C1306837
Disease	Renal Cell Carcinoma	CSMD3 SLC5A3 TGM2 UNC5C	5.28e-03	128	160	4	C0007134

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSQGFFFLKEHSSGV	nan	6	Q6ZS49
FTDSLLTGATNGHAF	ALX1	281	Q15699
TNSGDFLHDAFLSGA	ACOX2	586	Q99424
EAGELSFFNVSDGSH	BTNL9	456	Q6UXG8
SDGSHIFTFHDTFSG	BTNL9	466	Q6UXG8
GSLGGIFHFFSLSQV	CATSPERD	196	Q86XM0
SHDNGSQFFFTLGRA	CWC27	106	Q6UX04
RYGHDFSIGSTVSFS	CSMD3	1021	Q7Z407
GFGVHLQFVNFSTET	CSMD3	2146	Q7Z407
FHSSFNCFDFGVTVG	CACNA1E	536	Q15878
FSNASGLFEIHGATV	EIF2AK4	1516	Q9P2K8
IHDDFVTTFFVGFSN	AEBP1	466	Q8IUX7
FSHNEGTLSSGFLQE	CD160	151	O95971
GSYVSIHSSGFRDFL	DDX39A	36	O00148
FGATSLSFSAFFVVH	ADGRA3	1031	Q8IWK6
AFNGVDFEGTFHVNT	COMP	576	P49747
FHAALTFTVFAGGIN	ADGRA1	61	Q86SQ6
HNDVVRFLFGFGAST	ANKRD29	91	Q8N6D5
ELSSSQTLSHDGGFF	GKAP1	196	Q5VSY0
GAVATDFFTVLSSGH	AP5Z1	216	O43299
GVHGSSVAAESFFVF	ATP8B3	416	O60423
VAFNATVSAHFGEGS	CD163L1	1081	Q9NR16
SDNIFTHFVASFIAG	SLC25A10	196	Q9UBX3
THFVASFIAGGCATF	SLC25A10	201	Q9UBX3
QVSEGFHVGLTFQSF	BMP1	466	P13497
GSHSAFTSSFSFIRL	DISC1	201	Q9NRI5
FFHVSSGVDGDTTSS	ATG2B	826	Q96BY7
SFFTFGTLKSVGLSH	SLC25A16	206	P16260
SSGQSRGFAFVEFSH	RBM10	166	P98175
NGFSSHFVSAKTGDS	RAB28	151	P51157
LPFFVVFSNDHSSGT	GDF2	251	Q9UK05
SHILAVAVFFGSAAF	OR8G2P	256	Q6IF36
SLVAFGTSHGFGLFD	LLGL1	611	Q15334
HTSVSEFILVGFSAF	OR10H5	6	Q8NGA6
VSGFTTSALHSSFTF	OR2J1	151	Q9GZK6
ERSSTAFHGEIFGTS	KANSL1L	941	A0AUZ9
FIDGFILNHFGTLSF	KLHL36	166	Q8N4N3
SLGFVFSAFASDLLH	SLC16A11	116	Q8NCK7
AAGAGTFQDFSHIFL	KMT2C	311	Q8NEZ4
FHGGSSFTVLRCTSF	HHATL	176	Q9HCP6
TSFLFITSHFTSGDG	INPP5E	416	Q9NRR6
SFFFGCELSGHTRSF	NPM3	36	O75607
GNGDFSVYSASTHKF	HIF1AN	86	Q9NWT6
TSFPHESTFGVGNFN	GPBP1	236	Q86WP2
TIFSSVGFHGGSSAV	SLC2A10	256	O95528
SSFEGVSGHVVFDAS	GABBR1	516	Q9UBS5
GLTQFELTGHSVFDF	HIF1A	121	Q16665
KTQSQIASGFFTFSH	MCM3AP	166	O60318
SDGHTLAFTTEGEVF	HERC1	466	Q15751
ALFGTSGEHFNLFSG	GPATCH1	246	Q9BRR8
SVGRVSFSFSLTEGH	FCRL5	521	Q96RD9
DGFFLLGIFSHSQTD	OR2V1	11	Q8NHB1
DGFFLLGIFSHSTAD	OR2V2	11	Q96R30
SAHFFGGTEIFLLTA	OR4S1	101	Q8NGB4
FLNASFHIGGIFSLS	OR5B2	151	Q96R09
VSNVFSTAAFRFGHA	TPO	481	P07202
TLFAAHVSGAVLTFG	DRAM2	116	Q6UX65
TFLFNAFDTNHDGSV	KCNIP2	146	Q9NS61
HDGSVSFEDFVAGLS	KCNIP2	156	Q9NS61
FFTSNTHSSVVLQGF	KLHL9	26	Q9P2J3
ASNHSFLATITSFVG	LY75	841	O60449
SSVFLENSTFDEFGH	DPP4	86	P27487
SFTGHVSDINAVSFF	GNB4	221	Q9HAV0
GFKFTFSHSASAANG	PPP4R3B	771	Q5MIZ7
HDAGTGTVFLFFIAV	NEU4	91	Q8WWR8
IFHEGSNGTFIVTFD	ITGAD	866	Q13349
SENGFSLAGAAFTHD	NID2	601	Q14112
GFSALGAFVSITHFG	PLA2G4C	201	Q9UP65
HSSLAEFVFLGFASV	OR6N2	6	Q8NGY6
NSFATAAFRFGHTLI	PXDNL	1046	A1KZ92
NLFHFDESTTGSNFS	RGPD3	1281	A6NKT7
FVSDSSISAGGFHTT	CUBN	1716	O60494
TESFSSTGNSLTFHF	CUBN	1931	O60494
HVADNTFVFFTSDNG	GALNS	276	P34059
GFVVVSSSGHEDGFS	CEP104	6	O60308
FATDGFHAAASSANL	EYA4	451	O95677
SHFSDLGQSFSFHSG	IGSF11	336	Q5DX21
GCFTDFHIDFGGTSV	KDM2B	236	Q8NHM5
SFAHFTAGVFNVTLS	BPIFC	291	Q8NFQ6
SFFAFNAGHIAGSVN	DUSP1	31	P28562
FVEGSAGDSLTFHNN	FCN2	226	Q15485
VSGFFANAARFHSTG	DHX35	611	Q9H5Z1
DVFGDTSFLSNHGGS	CDC42EP1	56	Q00587
ILGSPFFSHFDGQDS	MAP3K20	596	Q9NYL2
GFLGTTTEVFHIASQ	ACOD1	41	A6NK06
SEFEGLFTTHKGNFQ	EPOR	291	P19235
VSSDHLFLFGGFTTD	KLHDC2	276	Q9Y2U9
SATFSGHGARSLLQF	HDDC2	6	Q7Z4H3
HFSTFQGETSADISF	CNTNAP2	811	Q9UHC6
GHFNVTNTTFDFDLF	MLLT1	526	Q03111
TIHFRSDISFQNTGF	DMBT1	1856	Q9UGM3
TFHGNFFVRSTDLLS	SEC24B	936	O95487
ISNGTFGFDGHTRSD	SLC20A2	326	Q08357
FFGGNLSSVFHIVVT	SLC38A11	271	Q08AI6
TSSTAGAFSALGAFH	CNTROB	661	Q8N137
LTSSLHFNGDFGDEV	MTMR3	1061	Q13615
QHLRGFFSDSTSFNI	PTCD2	156	Q8WV60
GCFTQFHFFFSLGTT	OR11H7	96	Q8NGC8
LGGTIHSLFQTSFVF	OR10G6	171	Q8NH81
TGSFGTISYAFFHAS	PCDHB3	271	Q9Y5E6
TQTSFLGTASAFRFH	PLA2G4D	196	Q86XP0
EFIFLGFSSFGKHQI	OR10J5	11	Q8NHC4
TDTHVFGLFVAANSG	OR4C5	211	Q8NGB2
NLFHFGESTTGSNFS	RGPD4	1281	Q7Z3J3
AGIVSFFNVTSHGSL	TRIM34	441	Q9BYJ4
ATGTAHFFNFLLNTT	SEMA3F	41	Q13275
LFQTGSSHERFLSFS	SYNE1	1356	Q8NF91
FDAGSTGTRVHVFQF	ENTPD6	106	O75354
AHARFFIGTSVSTFS	POFUT2	376	Q9Y2G5
TFHGNFFVRSTDLLS	SEC24A	761	O95486
GFSQSLLTFHLSFCG	OR5M1	156	Q8NGP8
FNSDTHSSTFDAGAG	GAPDH	286	P04406
YGVSGFQTTEHFLTA	GNL3L	351	Q9NVN8
RGHFSSTTGLFYSAE	PRKY	141	O43930
AHISGFISGLFLSFA	RHBDF1	771	Q96CC6
IGASLFVSNIGSEHF	SLC5A3	51	P53794
FASASIGLQTFNHSG	SLC17A9	341	Q9BYT1
GSHQVFDFRSSSSVG	TANC2	1461	Q9HCD6
FLFKHGSGSSAIFSA	TENM1	261	Q9UKZ4
SFGGHFDENQSFVGV	MPTX1	76	A8MV57
FDQATGGTAQFEAHS	IARS1	951	P41252
TATGAADNGFLSHNF	TNS3	1056	Q68CZ2
SANFGEAAHFVSTLG	SLC35F4	356	A4IF30
LQESGFSHSAFTFGI	TBL1XR1	16	Q9BZK7
NSNIVHIFSAGSAAF	SLC25A33	126	Q9BSK2
HIFSAGSAAFITNSL	SLC25A33	131	Q9BSK2
SLAFGGHIAFASYNS	SLC6A18	266	Q96N87
AFHASSTSVLVDGFT	SMAD5	286	Q99717
AFHASSTSVLVDGFT	SMAD1	286	Q15797
AFFHGGDSDSTAAIA	ADPRH	296	P54922
TGGSAASVNANFAHF	AGFG1	271	P52594
AGSFVLVAFSHSVGT	CLN3	136	Q13286
AGGSISHQVSFSYFN	SLC25A12	206	O75746
AAGGTTSHQVSFSYF	SLC25A13	206	Q9UJS0
FAFLSADGVHSSRGF	CLEC2A	146	Q6UVW9
LFSHVDFSGDGKSSG	CNOT1	51	A5YKK6
SLGTHSRFSEFTGFS	TRAK1	546	Q9UPV9
GLQTVFTDHSLFGFA	PIGA	146	P37287
ASTGYQGSSFVLGHF	TGM2	121	P21980
YLQESGFSHSAFTFG	TBL1X	66	O60907
GNGSAESSHFFAYLV	TGOLN2	376	O43493
HSIVSSFAFGLFGVF	TPTE	86	P56180
ISAAFSTENGFHSVG	TIAM2	106	Q8IVF5
GHSAFSVALIFVTAF	SLC35A5	301	Q9BS91
LLFSTNAHGRAFFAA	TMEM158	101	Q8WZ71
STHFENSFEGSSFAV	SLC7A7	211	Q9UM01
FGHFTGFNSSTLKDN	SLC12A9	236	Q9BXP2
HSFTGAFLFSLETQT	KCNJ16	116	Q9NPI9
GHSSFAFAGLAFASF	PLPP5	151	Q8NEB5
SFEHLSFGSQDDSAG	PIEZO2	1836	Q9H5I5
SFVSLGHNVFENDSF	UGT1A1	91	P22309
AFTVHFSGQFTGTAG	WT1	91	P19544
VSEGFHVGLTFQAFE	TLL2	496	Q9Y6L7
FEKSTNASFTLGHGF	ZNF281	676	Q9Y2X9
NASFTLGHGFQFVSL	ZNF281	681	Q9Y2X9
LQESGFSHSAFTFGI	TBL1Y	16	Q9BQ87
AFNGVDFEGTFHVNT	THBS3	771	P49746
ATGISFAIHGNFSGT	SF3B3	11	Q15393
YSFNSHGSIISIFGL	TMEM100	76	Q9NV29
FFGQHGGEVNSSAFS	WDR38	16	Q5JTN6
KTFFSTGQGNTEAFH	ZNF28	56	P17035
FGLFNTTSNIFRGHA	SEMA3E	326	O15041
IVHSIVSSFAFGIFG	TPTE2	66	Q6XPS3
FGLIVGDSQHSFPFS	ZNF148	676	Q9UQR1
SGFSGSHLESQYFER	TMEM217	186	Q8N7C4
SHGFVFSLNSRVFET	TLR5	296	O60602
TAFGSFNSLGGHLIV	UNC5C	531	O95185
AFSGGTSTFTVTAHR	TMEM25	86	Q86YD3
ASEGESTTAHFFLGA	PPIP5K1	6	Q6PFW1
STTAHFFLGAGDEGL	PPIP5K1	11	Q6PFW1
SVVAQTGSGGSFHEF	ZMYM3	366	Q14202
VVSNLGHSFFSQSFL	ZFYVE9	1011	O95405
GQGLTFTAASHVVFA	ZRANB3	401	Q5FWF4
GGTNSEFALHSLFEA	TRERF1	841	Q96PN7
GQEFHVSAGTLAFSV	SLC8A3	851	P57103
TFHLFIAAFVGAAAT	PLP1	236	P60201
SGHTSFFDKGAVNGF	NDEL1	306	Q9GZM8