Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionX11-like protein binding

CLSTN2 CLSTN1

1.30e-0431322GO:0042988
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH3 DDX60 CFTR WRN RNF213 RECQL DNAH7 MLH3 SLFN13 ATF7IP DNAH11

1.70e-0444113211GO:0016887
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH7 DNAH11

2.14e-04181323GO:0008569
GeneOntologyMolecularFunctionpyrophosphatase activity

DNAH3 DDX60 CFTR TRPM2 WRN RNF213 DNAJC27 RECQL DNAH7 RHOA RHOC MLH3 SLFN13 ATF7IP DNAH11

4.39e-0483913215GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DNAH3 DDX60 CFTR TRPM2 WRN RNF213 DNAJC27 RECQL DNAH7 RHOA RHOC MLH3 SLFN13 ATF7IP DNAH11

4.45e-0484013215GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DNAH3 DDX60 CFTR TRPM2 WRN RNF213 DNAJC27 RECQL DNAH7 RHOA RHOC MLH3 SLFN13 ATF7IP DNAH11

4.45e-0484013215GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DNAH3 DDX60 CFTR WRN RNF213 DNAJC27 RECQL DNAH7 RHOA RHOC MLH3 SLFN13 ATF7IP DNAH11

6.21e-0477513214GO:0017111
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

6.39e-0461322GO:0034647
GeneOntologyMolecularFunctionfour-way junction helicase activity

WRN RECQL

6.39e-0461322GO:0009378
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 DDX60 CFTR WRN RNF213 RECQL DNAH7 MLH3 SLFN13 ATF7IP TOP2A DNAH11

7.82e-0461413212GO:0140657
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH7 DNAH11

8.20e-04281323GO:0051959
GeneOntologyMolecularFunctionMutLalpha complex binding

ATR WRN

8.91e-0471322GO:0032405
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

1.18e-0381322GO:0032453
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

VPS11 UBR4 RNF213 BIRC7 TRIP12 MED24 FBXO24 KLHL9 HACE1 MIB1

1.20e-0347313210GO:0004842
GeneOntologyCellularComponentintegrin complex

ITGA1 TSPAN32 ITGAV ITGB2

5.35e-05321364GO:0008305
GeneOntologyCellularComponentspecific granule membrane

UBR4 TRPM2 ITGAV ITGB2 OLR1

3.22e-04911365GO:0035579
GeneOntologyCellularComponentXY body

ATR SCML2 MAEL

4.34e-04231363GO:0001741
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGA1 TSPAN32 ITGAV ITGB2

5.91e-04591364GO:0098636
GeneOntologyCellularComponentficolin-1-rich granule membrane

UBR4 TRPM2 ITGB2 RHOA

6.71e-04611364GO:0101003
DomainZINC_FINGER_C2H2_2

ZNF280A TRERF1 ZNF695 ZSCAN31 ZNF337 ZNF570 POGZ ZNF181 BNC1 ZNF547 ZNF532 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF512 ZNF292

1.02e-0777513121PS50157
DomainZINC_FINGER_C2H2_1

ZNF280A TRERF1 ZNF695 ZSCAN31 ZNF337 ZNF570 POGZ ZNF181 BNC1 ZNF547 ZNF532 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF512 ZNF292

1.06e-0777713121PS00028
DomainZnf_C2H2-like

ZNF280A TRERF1 ZNF695 ZSCAN31 ZNF337 ZNF570 POGZ ZNF181 BNC1 ZNF547 ZNF532 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF512 ZNF292

1.59e-0779613121IPR015880
DomainZnf_C2H2

ZNF280A TRERF1 ZNF695 ZSCAN31 ZNF337 ZNF570 POGZ ZNF181 BNC1 ZNF547 ZNF532 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF512 ZNF292

1.92e-0780513121IPR007087
DomainZnF_C2H2

ZNF280A TRERF1 ZNF695 ZSCAN31 ZNF337 ZNF570 POGZ ZNF181 BNC1 ZNF547 ZNF532 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF512 ZNF292

2.04e-0780813121SM00355
Domainzf-C2H2

TRERF1 ZNF695 ZSCAN31 ZNF337 ZNF570 POGZ ZNF181 BNC1 ZNF547 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF512 ZNF292

3.70e-0769313119PF00096
Domain-

ZNF280A TRERF1 ZNF695 ZSCAN31 ZNF337 ZNF570 ZNF181 ZNF547 ZNF532 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF292

1.25e-06679131183.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF280A TRERF1 ZNF695 ZSCAN31 ZNF337 ZNF570 ZNF181 ZNF547 ZNF532 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF292

1.71e-0669413118IPR013087
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH7 DNAH11

1.16e-04141313IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH7 DNAH11

1.16e-04141313IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH7 DNAH11

1.16e-04141313IPR013602
DomainDHC_N2

DNAH3 DNAH7 DNAH11

1.16e-04141313PF08393
DomainMT

DNAH3 DNAH7 DNAH11

1.16e-04141313PF12777
DomainAAA_8

DNAH3 DNAH7 DNAH11

1.16e-04141313PF12780
DomainARM-type_fold

VPS11 ATR STAG1 UBR4 FRYL HSPBP1 TRIP12 CLHC1 NF1 ULK4

1.41e-0433913110IPR016024
DomainDHC_fam

DNAH3 DNAH7 DNAH11

1.44e-04151313IPR026983
DomainDynein_heavy

DNAH3 DNAH7 DNAH11

1.44e-04151313PF03028
DomainDynein_heavy_dom

DNAH3 DNAH7 DNAH11

1.44e-04151313IPR004273
DomainCalsyntenin

CLSTN2 CLSTN1

1.46e-0431312IPR026914
DomainRQC_domain

WRN RECQL

1.46e-0431312IPR018982
DomainRQC

WRN RECQL

1.46e-0431312PF09382
DomainKRAB

ZNF695 ZNF337 ZNF570 ZNF181 ZNF547 ZNF41 ZNF611 ZNF420 ZNF81 ZNF565

2.19e-0435813110PS50805
DomainKRAB

ZNF695 ZNF337 ZNF570 ZNF181 ZNF547 ZNF41 ZNF611 ZNF420 ZNF81 ZNF565

2.19e-0435813110PF01352
DomainBTB-kelch_protein

KLHL28 KLHL9 KLHL15 KLHL12

2.31e-04431314IPR017096
DomainKRAB

ZNF695 ZNF337 ZNF570 ZNF181 ZNF547 ZNF41 ZNF611 ZNF420 ZNF81 ZNF565

2.78e-0436913110SM00349
DomainKRAB

ZNF695 ZNF337 ZNF570 ZNF181 ZNF547 ZNF41 ZNF611 ZNF420 ZNF81 ZNF565

2.84e-0437013110IPR001909
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

2.90e-0441312IPR013637
DomainRecQ_Zn_bind

WRN RECQL

2.90e-0441312PF16124
DomainRecQ_Zn-bd

WRN RECQL

2.90e-0441312IPR032284
DomainPLU-1

KDM5C KDM5D

2.90e-0441312PF08429
Domainzf-C2H2_6

TRERF1 ZNF695 ZSCAN31 ZNF570 ZNF181 ZNF532 ZNF611 ZNF420 ZBTB11

3.76e-043141319PF13912
DomainDNA_helicase_ATP-dep_RecQ

WRN RECQL

4.82e-0451312IPR004589
Domainzf-C5HC2

KDM5C KDM5D

4.82e-0451312PF02928
DomainZnf_C5HC2

KDM5C KDM5D

4.82e-0451312IPR004198
DomainIntegrin_dom

ITGA1 ITGAV ITGB2

6.93e-04251313IPR032695
DomainKelch

KLHL28 KLHL9 KLHL15 KLHL12

7.32e-04581314SM00612
DomainBACK

KLHL28 KLHL9 KLHL15 KLHL12

8.32e-04601314SM00875
Domain-

KLHL28 KLHL9 KLHL12

8.72e-042713132.130.10.80
DomainBACK

KLHL28 KLHL9 KLHL15 KLHL12

8.85e-04611314IPR011705
DomainBACK

KLHL28 KLHL9 KLHL15 KLHL12

8.85e-04611314PF07707
DomainClathrin

VPS11 WDR19

1.00e-0371312PF00637
DomainClathrin_H-chain/VPS_repeat

VPS11 WDR19

1.33e-0381312IPR000547
DomainKelch_1

KLHL28 KLHL9 KLHL15 KLHL12

1.48e-03701314PF01344
DomainKelch_1

KLHL28 KLHL9 KLHL15 KLHL12

1.48e-03701314IPR006652
DomainDUF1220

NBPF11 NBPF1

1.70e-0391312SM01148
DomainGal_Oxidase_b-propeller

KLHL28 KLHL9 KLHL12

1.72e-03341313IPR015916
DomainJmjN

KDM5C KDM5D

2.12e-03101312SM00545
DomainJmjN

KDM5C KDM5D

2.12e-03101312PF02375
DomainJMJN

KDM5C KDM5D

2.12e-03101312PS51183
DomainJmjN

KDM5C KDM5D

2.12e-03101312IPR003349
DomainBTB

KLHL28 KLHL9 KLHL15 KLHL12 ZBTB11

2.31e-031311315PF00651
DomainDUF1220

NBPF11 NBPF1

2.58e-03111312PF06758
DomainNBPF_dom

NBPF11 NBPF1

2.58e-03111312IPR010630
DomainNBPF

NBPF11 NBPF1

2.58e-03111312PS51316
DomainVWFA

COL6A1 ITGA1 ITGB2 PARP4

2.65e-03821314PS50234
DomainVWA

COL6A1 ITGA1 ITGB2 PARP4

2.89e-03841314SM00327
DomainARM-like

ATR STAG1 FRYL HSPBP1 TRIP12 NF1 ULK4

2.98e-032701317IPR011989
DomainAAA

DNAH3 CFTR RNF213 DNAH7 DNAH11

3.48e-031441315SM00382
DomainAAA+_ATPase

DNAH3 CFTR RNF213 DNAH7 DNAH11

3.48e-031441315IPR003593
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH11

4.20e-03141312IPR011704
DomainAAA_5

DNAH3 DNAH11

4.20e-03141312PF07728
Domain-

ATR FRYL HSPBP1 TRIP12 NF1 ULK4

4.81e-0322213161.25.10.10
Domain-

KDM5C KDM5D

4.83e-031513121.10.150.60
DomainBRIGHT

KDM5C KDM5D

4.83e-03151312SM00501
DomainARID_dom

KDM5C KDM5D

4.83e-03151312IPR001606
DomainARID

KDM5C KDM5D

4.83e-03151312PS51011
DomainARID

KDM5C KDM5D

4.83e-03151312PF01388
DomainVWF_A

COL6A1 ITGA1 ITGB2 PARP4

5.21e-03991314IPR002035
DomainBTB

KLHL28 KLHL9 KLHL15 KLHL12 ZBTB11

5.43e-031601315PS50097
DomainIntegrin_alpha_C_CS

ITGA1 ITGAV

5.49e-03161312IPR018184
Domain-

DNAH3 DDX60 CFTR WRN RNF213 DNAJC27 RECQL DNAH7 RHOA RHOC SLFN13 DNAH11

6.26e-03746131123.40.50.300
DomainIntegrin_alpha-2

ITGA1 ITGAV

6.94e-03181312IPR013649
DomainINTEGRIN_ALPHA

ITGA1 ITGAV

6.94e-03181312PS00242
DomainHATPase_c

MLH3 TOP2A

6.94e-03181312SM00387
DomainIntegrin_alpha2

ITGA1 ITGAV

6.94e-03181312PF08441
DomainIntegrin_alpha

ITGA1 ITGAV

6.94e-03181312IPR000413
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TRERF1 COL6A1 HAUS6 UBR4 POGZ GREB1L ZNF532 ATF7IP ZFHX3 ZBTB11 CNOT1

8.42e-074181361134709266
Pubmed

Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells.

ITGAV ITGB2 RHOA

1.16e-066136319346499
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

UBR4 ETFA DNAH7 ADCY2 WDR19 RHOA PARP4 NF1 MIB1 C5 ZNF512 CNOT1 DNAH11

1.45e-066381361331182584
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

HAUS6 RNF213 ZSWIM6 WDR19 ZNF532 SLMAP

2.99e-06101136610997877
Pubmed

Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.

ITGB2 RHOA VAV1

3.23e-068136315249579
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

STAG1 ZNF570 WRN RECQL POGZ TRIP12 SCML2 FANCI ZBTB11 ZNF512 TOP2A ZNF292

5.19e-066081361236089195
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B DCAF8 STAG1 UBR4 RAP1GAP2 POGZ TRIP12 USP16 OLR1 ZNF181 WDR19 ZNF532 SNX6 MIB1 ZNF565 ZBTB11 ZNF292

1.17e-0512851361735914814
Pubmed

Global landscape of HIV-human protein complexes.

DCAF8 CANX UBR4 RNF213 RECQL ITGB2 RHOC PARP4 OSBPL6 TOP2A

1.35e-054571361022190034
Pubmed

Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator.

CANX CFTR

1.52e-05213627513695
Pubmed

Classification of early age facial growth pattern and identification of the genetic basis in two Korean populations.

ZSWIM6 TRIM29

1.52e-052136235970861
Pubmed

RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts.

RHOA RHOC

1.52e-052136221454503
Pubmed

Calnexin Delta 185-520 partially reverses the misprocessing of the Delta F508 cystic fibrosis transmembrane conductance regulator.

CANX CFTR

1.52e-052136212208510
Pubmed

Activation of a bacterial virulence protein by the GTPase RhoA.

RHOA RHOC

1.52e-052136219887681
Pubmed

Cellular deficiency of Werner syndrome protein or RECQ1 promotes genotoxic potential of hydroquinone and benzo[a]pyrene exposure.

WRN RECQL

1.52e-052136225228686
Pubmed

Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle.

ATR WRN

1.52e-052136212629512
Pubmed

Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma.

RHOA RHOC

1.52e-052136212808121
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

1.52e-052136210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

1.52e-052136216416087
Pubmed

Vav1 phosphorylation is induced by beta2 integrin engagement on natural killer cells upstream of actin cytoskeleton and lipid raft reorganization.

ITGB2 VAV1

1.52e-052136212885870
Pubmed

Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects.

CANX CFTR

1.52e-052136215105504
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

1.52e-052136232081420
Pubmed

Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers.

RHOA RHOC

1.52e-052136220503409
Pubmed

Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.

RHOA RHOC

1.52e-05213627989340
Pubmed

Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer.

RHOA RHOC

1.52e-052136233825439
Pubmed

Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo.

RHOA RHOC

1.52e-052136220828398
Pubmed

Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

RHOA RHOC

1.52e-052136215668138
Pubmed

Clinical and prognostic significance of RhoA and RhoC gene expression in esophageal squamous cell carcinoma.

RHOA RHOC

1.52e-052136217896152
Pubmed

Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin.

CANX CFTR

1.52e-052136215923638
Pubmed

Sequence of rho small GTP-binding protein cDNAs from human retina and identification of novel 5' end cloning artifacts.

RHOA RHOC

1.52e-05213627835413
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

1.52e-05213627524912
Pubmed

Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.

NBPF11 NBPF1

1.52e-05213627700633
Pubmed

Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and DeltaF508 CFTR.

CANX CFTR

1.52e-052136218457676
Pubmed

Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells.

PRKCQ VAV1

1.52e-052136210725744
Pubmed

Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat.

CANX CFTR

1.52e-052136216546175
Pubmed

Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells.

PDE8A CFTR

1.52e-052136234936285
Pubmed

Activation of RHOA-VAV1 signaling in angioimmunoblastic T-cell lymphoma.

RHOA VAV1

1.52e-052136228832024
Pubmed

ABCs of RhoGTPases indicating potential role as oncotargets.

RHOA RHOC

1.52e-052136228508825
Pubmed

Expression of RhoA and RhoC in colorectal carcinoma and its relations with clinicopathological parameters.

RHOA RHOC

1.52e-052136219499974
Pubmed

RhoA G17E/Vav1 Signaling Induces Cancer Invasion via Matrix Metalloproteinase-9 in Gastric Cancer.

RHOA VAV1

1.52e-052136236617975
Pubmed

MIB1-mediated degradation of WRN promotes cellular senescence in response to camptothecin treatment.

WRN MIB1

1.52e-052136232652764
Pubmed

Identification of functional segments within the beta2I-domain of integrin alphaMbeta2.

ITGAV ITGB2

1.52e-052136212324470
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

1.52e-05213629060413
Pubmed

Ovarian clear cell carcinomas: RHO GTPases may contribute to explain their singular biologic behavior.

RHOA RHOC

1.52e-052136221208644
Pubmed

Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity.

RHOA RHOC

1.52e-052136219642867
Pubmed

Interaction of microglia and amyloid-beta through beta2-integrin is regulated by RhoA.

ITGB2 RHOA

1.52e-052136218981818
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

ATR DDX60 WRN FRYL TRIP12 PARP4 CNOT1

1.56e-05202136733005030
Pubmed

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels.

ITGA1 ITGAV ITGB2

1.63e-0513136320563599
Pubmed

Update on the Kelch-like (KLHL) gene family.

KLHL28 KLHL9 KLHL15 KLHL12

2.02e-0541136423676014
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH7 DNAH11

2.06e-051413639373155
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

DCAF8 UBR4 TRIP12 USP16 FANCI SLMAP TOP2A

2.13e-05212136733853758
Pubmed

Functional proteomics mapping of a human signaling pathway.

DGCR2 DSTN STAG1 CANX UBR4 TRIM29 TRIP12 ZNF41 ATF7IP PLAGL1 ZBTB11

2.23e-055911361115231748
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

VPS11 UBR4 RNF213 TRIP12 HACE1

3.71e-0595136529643511
Pubmed

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.

MED24 ULK4 DNAH11

3.82e-0517136323502783
Pubmed

Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study.

ATR TOP2A

4.54e-053136225846551
Pubmed

RhoA, RhoB and RhoC have different roles in cancer cell migration.

RHOA RHOC

4.54e-053136223488932
Pubmed

WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes.

ATR WRN

4.54e-053136222159421
Pubmed

A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.

RHOA RHOC

4.54e-053136212939257
Pubmed

Targeted disruption of protein kinase C epsilon reduces cell invasion and motility through inactivation of RhoA and RhoC GTPases in head and neck squamous cell carcinoma.

RHOA RHOC

4.54e-053136217018591
Pubmed

RhoA and RhoC differentially modulate estrogen receptor α recruitment, transcriptional activities, and expression in breast cancer cells (MCF-7).

RHOA RHOC

4.54e-053136224096540
Pubmed

Structural and mechanistic insights into the interaction between Rho and mammalian Dia.

RHOA RHOC

4.54e-053136215864301
Pubmed

Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets.

ITGAV RHOC

4.54e-053136218211678
Pubmed

The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns.

CLSTN2 CLSTN1

4.54e-053136212498782
Pubmed

Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases.

RHOA RHOC

4.54e-053136229500478
Pubmed

RhoA, RhoB and RhoC differentially regulate endothelial barrier function.

RHOA RHOC

4.54e-053136228949796
Pubmed

MicroRNA 10b promotes abnormal expression of the proto-oncogene c-Jun in metastatic breast cancer cells.

RHOC NF1

4.54e-053136227494896
Pubmed

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.

PRKCQ VAV1

4.54e-053136211956228
Pubmed

A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding.

ITGA1 ITGB2

4.54e-053136229079572
Pubmed

Assembly and misassembly of cystic fibrosis transmembrane conductance regulator: folding defects caused by deletion of F508 occur before and after the calnexin-dependent association of membrane spanning domain (MSD) 1 and MSD2.

CANX CFTR

4.54e-053136218716059
Pubmed

A p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.

RHOA RHOC

4.54e-053136221087931
Pubmed

RhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication.

RHOA RHOC

4.54e-053136220697357
Pubmed

Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases.

RHOA RHOC

4.54e-053136224447566
Pubmed

Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature.

ITGB2 VAV1

4.54e-053136219454683
Pubmed

Rho isoforms have distinct and specific functions in the process of epithelial to mesenchymal transition in renal proximal tubular cells.

RHOA RHOC

4.54e-053136219477269
Pubmed

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk.

ULK4 DNAH11

4.54e-053136222120009
Pubmed

RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis.

RHOA RHOC

4.54e-053136221757538
Pubmed

OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling.

OLR1 RHOA

4.54e-053136221130456
Pubmed

RhoA and RhoC are involved in stromal cell-derived factor-1-induced cell migration by regulating F-actin redistribution and assembly.

RHOA RHOC

4.54e-053136228536953
Pubmed

An interstitial telomere array proximal to the distal telomere of mouse chromosome 13.

ETFA ITGA1

4.54e-05313629166585
Pubmed

Divergence of Rho residue 43 impacts GEF activity.

RHOA RHOC

4.54e-053136222673745
Pubmed

The Role of RhoA, RhoB and RhoC GTPases in Cell Morphology, Proliferation and Migration in Human Cytomegalovirus (HCMV) Infected Glioblastoma Cells.

RHOA RHOC

4.54e-053136226741994
Pubmed

Clustered organization of Krüppel zinc-finger genes at Xp11.23, flanking a translocation breakpoint at OATL1: a physical map with locus assignments for ZNF21, ZNF41, ZNF81, and ELK1.

ZNF41 ZNF81

4.54e-05313628088786
Pubmed

Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC.

RHOA RHOC

4.54e-053136219421144
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5C KDM5D

4.54e-05313627544442
Pubmed

Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination.

ATR FANCI

4.54e-053136234828369
Pubmed

Prenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.

RHOA RHOC

4.54e-053136215642170
Pubmed

Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells.

RHOA RHOC

4.54e-053136227147504
Pubmed

Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes.

IL12RB2 TRPM2

4.54e-053136221709234
Pubmed

SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.

RHOA RHOC

4.54e-053136221242305
Pubmed

CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1.

PRKCQ VAV1

4.54e-053136214673152
Pubmed

Overexpression of Pin1 and rho signaling partners correlates with metastatic behavior and poor recurrence-free survival of hepatocellular carcinoma patients.

RHOA RHOC

4.54e-053136231324164
Pubmed

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton.

RHOA RHOC

4.54e-05313628816443
Pubmed

RhoA/C inhibits proliferation by inducing the synthesis of GPRC5A.

RHOA RHOC

4.54e-053136232719397
Pubmed

Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3.

SLC22A14 DLEC1

4.54e-053136210213508
Pubmed

Modulation of Both Intrinsic and Extrinsic Factors Additively Promotes Rewiring of Corticospinal Circuits after Spinal Cord Injury.

RHOA RHOC

4.54e-053136234759029
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DGCR2 KDM5C SPIRE1 POGZ WDR19 KLHL9 ZNF532 MIB1 SLMAP CNOT1

4.68e-055291361014621295
Pubmed

A Proteomic Variant Approach (ProVarA) for Personalized Medicine of Inherited and Somatic Disease.

DSTN CANX CFTR

5.41e-0519136329924966
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CANX UBR4 RECQL FRYL POGZ TRIP12 NF1 FANCI ZBTB11 ZNF512 CNOT1

5.50e-056531361122586326
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

STAG1 UBR4 RNF213 POGZ DERA MED24 SCML2 FANCI

6.24e-05341136832971831
Pubmed

Characterization of the zinc-induced Shank3 interactome of mouse synaptosome.

COL6A1 CANX ETFA PHYHIP ZFHX3

7.16e-05109136529111324
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF8 NBPF11 NBPF1

7.39e-0521136316079250
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF695 ZSCAN31 ZNF337 ZNF570 ZNF181 BNC1 ZNF547 ZNF532 ZNF41 ZNF611 PLAGL1 ZFHX3 ZNF420 ZNF81 ZNF565 ZBTB11 ZNF512 ZNF292

9.69e-087181021828
GeneFamilyKelch like|BTB domain containing

KLHL28 KLHL9 KLHL15 KLHL12

9.06e-05421024617
GeneFamilyDyneins, axonemal

DNAH3 DNAH7 DNAH11

1.12e-04171023536
GeneFamilyNeuroblastoma breakpoint family

NBPF8 NBPF11 NBPF1

2.84e-04231023662
GeneFamilyRecQ like helicases

WRN RECQL

3.12e-04510221049
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL28 KLHL9 KLHL15 KLHL12 ZBTB11

9.73e-041341025861
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

3.15e-03151022418
GeneFamilyX-linked mental retardation|Angiotensin receptors

KDM5C ZNF41 ZNF81

3.33e-03531023103
GeneFamilyCadherin related

CLSTN2 CLSTN1

4.06e-0317102224
GeneFamilyCD molecules|Integrin alpha subunits

ITGA1 ITGAV

4.55e-031810221160
GeneFamilyRho family GTPases

RHOA RHOC

5.60e-03201022390
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_500

TDRD5 USP26 SCML2 MAEL ZNF420

3.03e-06381275gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k3_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

TDRD5 USP26 SCML2 MAEL ZNF420 FGGY

1.21e-05851276gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k1_1000
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#5_top-relative-expression-ranked_500

DOCK4 RNF213 GREB1L BNC1 SCML2 MIB1

1.79e-05911276gudmap_developingGonad_e12.5_ovary_k5_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_200

USP26 SCML2 MAEL

7.25e-05141273gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_200
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CLSTN2 SLC9C2 DNAH7 CFAP54 OSBPL6 ULK4 DLEC1 DNAH11

9.57e-09197135974a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNAH3 GPR87 TRIM29 DNAH7 ADCY2 ADAM28 CFAP54 DLEC1

1.81e-072001358cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNAH3 GPR87 TRIM29 DNAH7 ADCY2 ADAM28 CFAP54 DLEC1

1.81e-072001358a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 SLC9C2 DNAH7 ADCY2 CFAP54 DLEC1 DNAH11

4.81e-0715513575f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 SLC9C2 DNAH7 ADCY2 CFAP54 DLEC1 DNAH11

4.81e-0715513570944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 PHYHIP DNAH7 CFAP54 FANCI DLEC1 DNAH11

5.25e-071571357410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERVV-2 CFTR GPR87 TRIM29 ADCY2 ADAM28 DNAH11

7.33e-0716513571a114eacaab598f755a173a3fed842ba91f689dd
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERVV-2 CFTR GPR87 TRIM29 ADCY2 ADAM28 DNAH11

7.33e-0716513579cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

DNAH3 DNAH7 CFAP54 OSBPL6 GJB7 DISP1 DNAH11

7.95e-07167135726cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A1 PHYHIP CLSTN2 BIRC7 SLC35F4 KLHL15 PLD5

1.58e-0618513579faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH7 CFAP54 SLFN13 OSBPL6 DLEC1 DNAH11

1.58e-061851357f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 SLFN13 DLEC1 DNAH11

1.58e-06185135730f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 DNAJC27 PARP4 SLC22A14 MIB1 VPS13B DNAH11

1.63e-06186135777bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 DNAJC27 PARP4 SLC22A14 MIB1 VPS13B DNAH11

1.63e-06186135713bc41c60fd628af31899a5e8b480e06cc4781be
ToppCellfacs-Thymus-Flowthrough-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TDRD5 TSPAN32 ITGB2 CCNG2 LIMD2 KLHL9 VAV1

2.02e-0619213577a0ef1702d6538e5611cfdc633d8558f9523845c
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TDRD5 TSPAN32 ITGB2 CCNG2 LIMD2 KLHL9 VAV1

2.02e-06192135705043fb75319b64f5ed7aee6a232309dcae891b8
ToppCellbackground-NK_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

TRERF1 IL12RB2 GPR18 TSPAN32 ITGB2 SLFN13 PRKCQ

2.09e-061931357f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B CFTR RAP1GAP2 DNAH7 ADCY2 GREB1L CFAP54

2.16e-061941357f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH7 CFAP54 SLFN13 ULK4 DLEC1 DNAH11

2.16e-0619413574a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH7 FBXO24 CFAP54 DLEC1 GJB7 TOP2A DNAH11

2.39e-0619713576e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERVV-2 GPR87 DNAH7 ADCY2 ADAM28 CFAP54 DLEC1

2.56e-06199135760919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERVV-2 GPR87 DNAH7 ADCY2 ADAM28 CFAP54 DLEC1

2.56e-0619913576aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAH3 GPR87 SLC9C2 DNAH7 ADCY2 CFAP54 DLEC1

2.64e-062001357da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAH3 GPR87 SLC9C2 DNAH7 ADCY2 CFAP54 DLEC1

2.64e-06200135772c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 GPR87 DNAH7 CFAP54 DLEC1 DNAH11

6.06e-061481356d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 GPR87 DNAH7 CFAP54 DLEC1 DNAH11

6.06e-061481356c8e93b87212f55774223caa385859c566fa1981f
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RECQL TSPAN32 MAEL PRKCQ GJB7 TOP2A

6.30e-0614913561328ce0104d40215ee68abfdbf74eb47b87a7b5b
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH7 CFAP54 DLEC1 GJB7 DNAH11

7.61e-0615413564e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH7 ADCY2 CFAP54 DLEC1 DNAH11

7.61e-0615413569ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH7 CFAP54 DLEC1 GJB7 DNAH11

7.61e-0615413567556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH7 ADCY2 CFAP54 DLEC1 DNAH11

7.61e-06154135658072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS-IL1RA-Epithelial_airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR87 TRIM29 ADCY2 ADAM28 DLEC1 DNAH11

9.82e-061611356472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PHYHIP CLSTN2 ZNF181 SLMAP OSBPL6 DNAH11

1.05e-0516313561e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 GPR87 ADCY2 ADAM28 CFAP54 DNAH11

1.09e-051641356e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellLPS_only-Epithelial_airway-Club_cells-Airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERVV-2 DSG3 GPR87 ADCY2 ADAM28 PLD5

1.09e-051641356b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCellLPS_only-Epithelial_airway-Club_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERVV-2 DSG3 GPR87 ADCY2 ADAM28 PLD5

1.09e-051641356c5b2001280a43da855017361a3f6071a0e492848
ToppCellLPS_only-Epithelial_airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERVV-2 DSG3 GPR87 ADCY2 ADAM28 PLD5

1.09e-05164135656e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL12RB2 GPR18 WRN SLC35F4 ZNF547 DLEC1

1.17e-051661356ceb0a48c0d853448fd45ac31dde046df9a178571
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH7 CFAP54 OSBPL6 ULK4 DNAH11

1.29e-051691356fba841664939c771881ba97f14ef1df6635c04ff
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH7 CFAP54 OSBPL6 GJB7 DNAH11

1.68e-051771356c38138fb5ad9766c2d240811210c854338cd612e
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-mature_NK_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 IL12RB2 GPR18 ITGB2 LIMD2 PRKCQ

1.74e-051781356291ffc52b824e4f59078147eb640ef34e24fb450
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

1.74e-051781356de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SLC9C2 DNAH7 SLFN13 DLEC1 DNAH11

1.74e-0517813563b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH7 CLHC1 CFAP54 DLEC1 DNAH11

1.79e-0517913565e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_bright-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IL12RB2 RNF213 TRIM29 ITGB2 RHOC SLFN13

1.91e-0518113569c4f9abb9335da2b07644bca8faff1baa1bb9f5b
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

1.91e-051811356dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

1.97e-0518213567ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

1.97e-051821356fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR18 ITGB2 LIMD2 CFAP54 PRKCQ VAV1

2.03e-0518313562e36bbc241682e47e880be21c1503abd7d0c3082
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.09e-0518413565daff849625f2f41d56615569c0ed59cd733b34c
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.16e-05185135618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

STAG1 ITGA1 PARP4 ZNF41 SLMAP VPS13B

2.22e-05186135603db813598b67b1e08f759758a1c2023396921fa
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.29e-0518713569e10ed56090d82589bc457788282f664b70ace4b
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.36e-05188135661a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.36e-05188135634b11f72ca73153d02edcd09b38983ad1a504659
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 TRIM29 DNAH7 SLFN13 DLEC1 DNAH11

2.36e-051881356606907c865bd2f11bb6474932716550f7723d858
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.36e-0518813562b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.43e-051891356a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.43e-05189135668a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR18 TSPAN32 ITGB2 LIMD2 PRKCQ VAV1

2.43e-051891356224d8304cc87b8573a4a78cf88a49d41564f7a47
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.43e-051891356b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.43e-05189135627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH7 CFAP54 SLFN13 DLEC1 DNAH11

2.51e-0519013567031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellSevere-Lymphoid-T-NK|Severe / Condition, Lineage, Cell class and cell subclass

IL12RB2 ITGA1 TSPAN32 LIMD2 FANCI TOP2A

2.51e-05190135660642de433f84fa2cecd796c3a1a4aab9219d3db
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH7 CFAP54 SLFN13 DLEC1 DNAH11

2.51e-051901356426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFTR RAP1GAP2 DNAH7 ADCY2 GREB1L CFAP54

2.58e-05191135660ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.58e-051911356e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.58e-0519113569d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 SLC9C2 DNAH7 CFAP54 DLEC1 DNAH11

2.58e-0519113561c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRERF1 IL12RB2 RAP1GAP2 TSPAN32 SLFN13 PRKCQ

2.74e-0519313561cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCellCOVID-19-lung-NK/NKT|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 IL12RB2 RAP1GAP2 TSPAN32 ITGB2 PRKCQ

2.74e-051931356c24b44fcc92fff42ebba6f1aff91c7aaea179e56
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAH3 DNAH7 CFAP54 OSBPL6 DLEC1 DNAH11

2.82e-051941356756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFTR RAP1GAP2 DNAH7 ADCY2 GREB1L CFAP54

2.82e-0519413566b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellT/NK_cells-CD56bright_NK_cell|T/NK_cells / Lineage and Cell class

IL12RB2 ITGB2 ADAM28 RHOC CCNG2 SLFN13

2.90e-051951356d2c8f5c114b1864b509fad449aa4492dfc61113c
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DNAH7 CFAP54 SLFN13 DLEC1 DNAH11

2.90e-0519513563486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH3 DNAH7 ADCY2 CFAP54 OSBPL6 DLEC1

2.90e-05195135660067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid-Microglia|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RNF213 RECQL ITGB2 ADAM28 FBXO24 ULK4

2.98e-05196135689a0ccd0684777927d99d5fc5b7c498f3f124250
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RNF213 RECQL ITGB2 ADAM28 FBXO24 ULK4

2.98e-05196135691a8c4798572d6c1f03cef5e8e5464ed0046c7cf
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-T_reg|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB2 GPR18 ITGB2 LIMD2 PRKCQ TOP2A

2.98e-0519613566362fb0b5dc923f19a76b605d7289a16f89220e3
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CANX ITGB2 RHOA ZFHX3 VAV1 SLC35A5

3.07e-051971356e73ca8c8f42cbcc56eaa5fe3d69abd1ce7b7bbca
ToppCellfacs-Brain_Myeloid-Cortex_|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CANX ITGB2 RHOA ZFHX3 VAV1 SLC35A5

3.07e-05197135681379fe6bd14a1ba26f4a159497262adcb600b18
ToppCellfacs-Brain_Myeloid-Cortex_-18m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CANX ITGB2 RHOA ZFHX3 VAV1 SLC35A5

3.07e-051971356271c75f491d03bd248c7ec037ef02e39456f3ac0
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CANX ITGB2 RHOA ZFHX3 VAV1 SLC35A5

3.07e-0519713569db329c6fea532dd1afb624f4c29c92407f45568
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH3 GPR87 DNAH7 ADAM28 CFAP54 DLEC1

3.16e-051981356e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B DOCK4 STAG1 ZSWIM6 NF1 VPS13B

3.16e-0519813561996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH3 GPR87 DNAH7 ADAM28 CFAP54 DLEC1

3.16e-051981356e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

TDRD5 DNAH3 ERVV-2 GPR87 DNAH7 CFAP54

3.16e-051981356e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

TDRD5 DNAH3 ERVV-2 GPR87 DNAH7 CFAP54

3.16e-051981356ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNF213 FRYL SLFN13 ATF7IP VPS13B ZNF292

3.25e-051991356f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Airway-Club|LPS_only / Treatment groups by lineage, cell group, cell type

TDRD5 ERVV-2 GPR87 ADAM28 CFAP54 PLD5

3.25e-051991356165ac94b2d56072ad43358b5127d77555221e2d8
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAH3 GPR87 DNAH7 ADCY2 CFAP54 DLEC1

3.25e-05199135615f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellproximal-Epithelial-Ciliated|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAH3 DNAH7 CFAP54 OSBPL6 DLEC1 DNAH11

3.25e-0519913569700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP2 TSPAN32 ITGB2 SLFN13 PRKCQ VAV1

3.25e-0519913567d69785717073491b5fb81bf24db0175f86cd0b0
ToppCellproximal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAH3 DNAH7 CFAP54 OSBPL6 DLEC1 DNAH11

3.25e-0519913561188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 RAP1GAP2 RNF213 TSPAN32 ITGB2 PRKCQ

3.25e-051991356eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCellproximal-Epithelial-Ciliated-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAH3 DNAH7 CFAP54 OSBPL6 DLEC1 DNAH11

3.25e-0519913562e8ace105c4e2405baa06d953e52888b54e2d055
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

DNAH3 DNAH7 CFAP54 OSBPL6 DLEC1 DNAH11

3.34e-0520013569ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAH3 SLC9C2 DNAH7 ADCY2 CFAP54 DLEC1

3.34e-05200135696701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL12RB2 RAP1GAP2 TSPAN32 ITGB2 LIMD2 PRKCQ

3.34e-0520013560b65855617fb7730de48facf411e2a8980f9f780
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DNAH3 DNAH7 CFAP54 OSBPL6 DLEC1 DNAH11

3.34e-052001356bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
Diseaseintellectual disability (implicated_via_orthology)

ZNF280A KDM5C UBR4 POGZ KDM5D ITGAV ATF7IP

4.02e-08751297DOID:1059 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

1.13e-0441292DOID:0060809 (implicated_via_orthology)
Disease1-myristoyl-2-docosahexaenoyl-GPC (14:0/22:6) measurement

GREB1L MIB1

1.88e-0451292EFO_0800454
Diseaseeosinophil count

TRERF1 DNAH3 PDE8A ZSCAN31 ATR RAP1GAP2 DNAJC27 TSPAN32 CLSTN1 DNAH7 MED24 ATF7IP PLAGL1 ZNF420 GJB7 SLC35A5 ZNF292

2.70e-04148812917EFO_0004842
DiseaseNeural crest tumor

HACE1 TOP2A

3.93e-0471292C2931189
Diseaseulcerative colitis (implicated_via_orthology)

RHOA RHOC

3.93e-0471292DOID:8577 (implicated_via_orthology)
Diseaseperoxisomal biogenesis disorder (implicated_via_orthology)

RHOA RHOC

5.22e-0481292DOID:0080377 (implicated_via_orthology)
Diseaseglycylvaline measurement

PRKCQ DNAH11

5.22e-0481292EFO_0021129
DiseaseGlioma

ATR TRIM29 NF1 TOP2A

5.86e-04871294C0017638
DiseaseColorectal Carcinoma

UNC13B DNAH3 DSTN CFTR WRN GPR87 CLSTN2 MLH3 NF1 ZNF292

1.06e-0370212910C0009402
DiseaseAL amyloidosis

ULK4 DNAH11

1.22e-03121292MONDO_0019438
Diseasebreast cancer (is_marker_for)

KDM5C ITGA1 RHOA RHOC ZFHX3

1.35e-031851295DOID:1612 (is_marker_for)
DiseaseGastrointestinal Stromal Tumors

RHOA ZBTB11 DISP1

1.38e-03501293C0238198
DiseaseX-12063 measurement

PDE8A TRPM2 NF1 OTOGL SLMAP

1.38e-031861295EFO_0021283
Diseasemultiple myeloma, monoclonal gammopathy

ULK4 DNAH11

1.67e-03141292EFO_0000203, EFO_0001378
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

2.19e-03161292DOID:0050888 (implicated_via_orthology)
Diseasecolon cancer (is_marker_for)

KDM5C CCNG2 NF1

2.22e-03591293DOID:219 (is_marker_for)
DiseaseMoyamoya Disease

RNF213 NF1

2.47e-03171292C0026654
Diseasebreast carcinoma (is_marker_for)

ADAM28 FZD1 ZFHX3

3.06e-03661293DOID:3459 (is_marker_for)
Diseasepulse pressure measurement

COL6A1 HAUS6 PDE8A ETFA RNF213 FRYL POGZ ITGA1 ULK4 ZFHX3 DLEC1 CNOT1 FGGY KLB

3.14e-03139212914EFO_0005763
DiseaseIntellectual Disability

STAG1 KDM5C POGZ NF1 KLHL15 ZBTB11 ZNF292

3.59e-034471297C3714756
DiseaseMalignant Glioma

TRIM29 NF1 TOP2A

3.61e-03701293C0555198
Diseasemixed gliomas

TRIM29 NF1 TOP2A

3.61e-03701293C0259783
Diseasestroke

RAP1GAP2 TRIM29 ULK4 ZFHX3

3.74e-031441294EFO_0000712
DiseaseTesticular Germ Cell Tumor

PDE8A CLSTN1 ATF7IP

4.06e-03731293EFO_1000566
DiseaseGranulomatous Slack Skin

RHOA PRKCQ

4.14e-03221292C0376407
DiseaseBronchiectasis

CFTR DNAH11

4.14e-03221292C0006267
Diseaselung cancer (is_implicated_in)

ATR CFTR RECQL

4.22e-03741293DOID:1324 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
IGIVQKSSLRFLKCC

TDRD5

566

Q8NAT2
IACKACGQVILKTEL

USP26

446

Q9BXU7
TTFKCLSCVKVLKNI

ZNF280A

296

P59817
FIKSLNVEKKTDCCI

CFAP54

2006

Q96N23
RTLKQAFADCTVILC

CFTR

1386

P13569
NICCDAKTCKIKATF

ADAM28

431

Q9UKQ2
ELKNTCKAVLACVGV

GPR18

131

Q14330
QCDICKKTFKNACSV

BNC1

721

Q01954
EAQLKACNCRLIFSK

CCNG2

186

Q16589
CSKEQEFKSILFSLC

DNAH11

4071

Q96DT5
TCKVCLDRAVSIVFV

BIRC7

251

Q96CA5
CFFNLLIKCVSSRIK

ERVV-2

476

B6SEH9
LKITSTIKCFNEATC

CLSTN1

621

O94985
VIFCLSADKKCIIVE

DSTN

36

P60981
LKVSSKVQCFGEDVC

CLSTN2

601

Q9H4D0
VACQKCHKVLFAISE

DISP1

686

Q96F81
GLSTQCECNIKVKDV

DSG3

246

P32926
SKICKENSREDALFC

FANCI

1011

Q9NVI1
ADFSICCKLKIIEID

DEFB131A

51

P59861
CIDKVIAKCTGSAIN

PRKCQ

201

Q04759
LAVCKKIAYCISNSL

MAEL

296

Q96JY0
SLRAQVKETCAACQK

LIMD2

31

Q9BT23
NIIFVVCANKIDCTK

DNAJC27

126

Q9NZQ0
TTLFVCKLACINSDE

IL12RB2

96

Q99665
QCIKCKTTCFLSALA

KDM5D

696

Q9BY66
FLKSCKSSCVKLQVE

DDX60

626

Q8IY21
RKDSKLCSVLTQDFC

MLH3

906

Q9UHC1
KCTVTKEAQAVLACF

PDE8A

106

O60658
ELSATQCCKNTKRVA

DCAF8

266

Q5TAQ9
FCKETASRIAKVCAE

FRYL

2121

O94915
SCEVVSKANCAKLKQ

HACE1

566

Q8IYU2
CKVFLISGVSLDNCV

KLHL9

141

Q9P2J3
EAAFKCCAAAIIVLT

PKLR

461

P30613
VLQDSCFLQIKCDTK

PARP4

1531

Q9UKK3
VCINATVCFDVKLKS

ITGA1

696

P56199
CILAAFSICQKKANL

OLR1

256

P78380
KFLKGATLCVICQDR

GREB1L

1866

Q9C091
KEKCFVTQLACFLAN

NBPF1

581

Q3BBV0
SSVCICKLTFVKVNY

OSBPL6

756

Q9BZF3
KEITLFLSACNVCLD

GPR87

296

Q9BY21
CVVCSDKKAAVLFQP

MIB1

866

Q86YT6
LFFCEVVQVIKLACS

OR7G1

176

Q8NGA0
SLGCVLSQECTKFKV

ITGB2

16

P05107
LSQECTKFKVSSCRE

ITGB2

21

P05107
LVKVQCSAELKFFLC

FZD1

156

Q9UP38
FAQAKACKVLVEKCT

GUCD1

116

Q96NT3
QDTCNCIKSRIKLEF

ADCY2

221

Q08462
KKICEVICSLLFLFK

ATR

121

Q13535
KGVKQACCEFLESQL

KLHL12

116

Q53G59
VVKFCCSFLLAKICL

KLHL15

116

Q96M94
QIKLVLKECCAFLES

KLHL28

116

Q9NXS3
CARILSNVFCLIKKN

DOCK4

851

Q8N1I0
FLKNVTAQICIDKKC

COL6A1

801

P12109
DLAKALAKQCVVFNC

DNAH3

1441

Q8TD57
ACCVVTKKVVQGIDL

FGGY

61

Q96C11
KAFTECCVVASQLRA

C5

726

P01031
TSNIKIQKVCEGAAC

C5

1511

P01031
TALKVSCFNVRFCLK

ITGAV

496

P06756
ITAIILKDFNVCKCQ

TMEM63B

371

Q5T3F8
LAKAVAKQCVVFNCS

DNAH7

1341

Q8WXX0
LQLFTEECLKFCASK

REXO1L1P

301

Q8IX06
FLVILFCCSGKKQTS

CANX

496

P27824
KLCALQCAVFDKTLA

ATF7IP

606

Q6VMQ6
SSFLCKRSQTCVDIK

DGCR2

261

P98153
ASFVKLQVKVPLCAC

FBXO24

451

O75426
VICKQDLECLAFTKL

HAUS6

691

Q7Z4H7
ENTECTVCLFLVQKK

KLB

981

Q86Z14
IELSFLVLKCFIKCC

GJB7

196

Q6PEY0
CSKLTFSCEKRSVQK

DLEC1

231

Q9Y238
VCDAVKALKAAGCNI

DERA

106

Q9Y315
ASVLDFCKNRQLCKV

SLC22A14

366

Q9Y267
LCVIKVKAFCCVVFS

SLFN13

311

Q68D06
ADFSICCKLKIIQID

DEFB131B

51

A0A096LNP1
DATEFACLKCIVTFK

NR2E1

281

Q9Y466
KCFDNDIVCSKSVLI

OTOGL

991

Q3ZCN5
TLNFTLVNCSKKCDV

OTOGL

2156

Q3ZCN5
CGKTCLLIVFSKDQF

RHOC

16

P08134
TSKKVCVQLVCGAFS

OR10J6P

136

Q8NGY7
FTCEILAVLKLACTS

OR2K2

176

Q8NGT1
CDTVRVKALFAISCL

HSPBP1

201

Q9NZL4
CGKTCLLIVFSKDQF

RHOA

16

P61586
QKAVKSCLVCQASFC

TRIM29

181

Q14134
CQLCGKTFLTLEKFT

PLAGL1

6

Q9UM63
FLLTKLTNAENACCK

RAP1GAP2

431

Q684P5
AICTEIANCSLKVKF

PLD5

401

Q8N7P1
FRSLKEKCFVTQVAC

NBPF8

271

Q3BBV2
EKCFVTQVACFLAKQ

NBPF8

276

Q3BBV2
FRSLKEKCFVTQVAC

NBPF11

306

Q86T75
EKCFVTQVACFLAKQ

NBPF11

311

Q86T75
VSCLVAGTKCDKVAQ

ETFA

51

P13804
KKLRVVLFALCCNTE

POGZ

976

Q7Z3K3
TDNIKGKVCSLAVCA

MED24

606

O75448
LLDIACNKFLTCSVE

PHYHIP

256

Q92561
TLNKVATCGDNCIKI

WDR19

286

Q8NEZ3
KVALIQLCVSESKCY

WRN

96

Q14191
QTVKLPVDKTTSCCF

RGN

236

Q15493
KKLTATDVSALFCCN

SLC35F4

271

A4IF30
KAKCLALAQIVYSEC

CLHC1

416

Q8NHS4
ELACCFIQKTAVEKA

CNOT1

1501

A5YKK6
VLTDAQKILCIEKCF

RECQL

261

P46063
QKILCIEKCFTFTAS

RECQL

266

P46063
QCEAVSKFIGECKIL

RNF213

4396

Q63HN8
CKVCAKTFETEAALN

ZNF532

1266

Q9HCE3
QFQCELCVKSFVTKR

ZBTB11

706

O95625
CKECGKAFIRVSQLT

ZNF565

461

Q8N9K5
EECGKAFNLCSVLTK

ZNF695

271

Q8IW36
KVCGKAFLLSSCLVQ

ZSCAN31

326

Q96LW9
IFQKTKCSICNSALE

VPS11

816

Q9H270
CTLKCKNVAEENTRV

USP16

726

Q9Y5T5
RCVSCNVSVDKEQKL

MIS18A

111

Q9NYP9
CVLVSFCVIKKDHQS

SLC35A5

66

Q9BS91
VQACVDCALETKTVF

SCML2

396

Q9UQR0
LAAIQDVFLCCGKKS

TSPAN32

146

Q96QS1
VCVDCKKFISEIISS

SPIRE1

701

Q08AE8
QDCIAAALACSKILK

TRPM2

646

O94759
CTFIHQFIECQKKLI

SLMAP

406

Q14BN4
CLKNIRTFLSTCCEK

VAV1

71

P15498
KQTLKEFRCQVSDCS

ZNF292

2166

O60281
KCDVCQKAFRFLSSL

ZNF840P

236

A6NDX5
AIACVKLCKASTYIN

NF1

321

P21359
RKTVKSFLAVCQQCL

STAG1

766

Q8WVM7
ASQVVKDCVKACLNS

UNC13B

916

O14795
LCCQKFEKISESAKQ

SNX6

346

Q9UNH7
TCQLSEKFIKAAIGC

TOP2A

391

P11388
CNVAISFDRCKITSV

ZSWIM6

246

Q9HCJ5
CTQCGKVFTLKSNLI

ZNF41

371

P51814
CNECGKFFSLKSVLI

ZNF547

326

Q8IVP9
KLLKCNDCEKVFSQS

ZNF570

216

Q96NI8
KVINFSDCTVCLDKR

VPS13B

201

Q7Z7G8
CFIKLCITLNEGKSI

VPS13B

3501

Q7Z7G8
CKECRKVFTQLSQLI

ZNF420

281

Q8TAQ5
KCTICDKAFVRNSLL

ZNF611

651

Q8N823
KQIAVCESIYQKLCE

SLC9C2

761

Q5TAH2
LVQEATTEALKLCFC

TTC37

1466

Q6PGP7
KKSVESTCLCFARLV

TRIP12

616

Q14669
SLCNKLCTFTITQKE

UBR4

1656

Q5T4S7
KCLLCQKEFVSESGV

ZNF512

441

Q96ME7
ECNKCLKVFSSLSFL

ZNF181

406

Q2M3W8
ICTKCGKAFIQNSEL

ZNF81

331

P51508
TINFVAILCTDKCKR

ULK4

26

Q96C45
CKQCEKSFSLKANLL

ZNF337

546

Q9Y3M9
KCTVCKESFTQKNIL

ZFHX3

1546

Q15911
FDAKNKLTCSICLKE

TRERF1

506

Q96PN7
QCIKCKTTCFLSALA

KDM5C

706

P41229