Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	4.32e-06	2	42	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	4.32e-06	2	42	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	4.32e-06	2	42	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	4.32e-06	2	42	2	GO:0004354
GeneOntologyMolecularFunction	L-leucine binding	GLUD1 GLUD2	9.01e-05	7	42	2	GO:0070728
GeneOntologyMolecularFunction	store-operated calcium channel activity	TRPC7 TRPC6	2.81e-04	12	42	2	GO:0015279
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	UGT3A2 GALNT7 UGGT1 UGT3A1	2.96e-04	153	42	4	GO:0008194
GeneOntologyMolecularFunction	inositol 1,4,5 trisphosphate binding	TRPC7 TRPC6	3.87e-04	14	42	2	GO:0070679
GeneOntologyMolecularFunction	channel activity	BAX SLC9C1 TRPC7 TRPC6 SCN7A PKD2	7.54e-04	525	42	6	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	BAX SLC9C1 TRPC7 TRPC6 SCN7A PKD2	7.61e-04	526	42	6	GO:0022803
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors	GLUD1 GLUD2	8.01e-04	20	42	2	GO:0016638
GeneOntologyMolecularFunction	NAD+ binding	GLUD1 GLUD2	8.01e-04	20	42	2	GO:0070403
GeneOntologyMolecularFunction	hexosyltransferase activity	UGT3A2 GALNT7 UGGT1 UGT3A1	9.90e-04	211	42	4	GO:0016758
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN7A PKD2	1.36e-03	26	42	2	GO:0005248
GeneOntologyMolecularFunction	protein homodimerization activity	BAX HMGCS1 RRM2 TRPC6 GLUD1 GLUD2 PKD2	1.42e-03	815	42	7	GO:0042803
GeneOntologyMolecularFunction	glucuronosyltransferase activity	UGT3A2 UGT3A1	2.46e-03	35	42	2	GO:0015020
GeneOntologyMolecularFunction	calcium channel activity	TRPC7 TRPC6 PKD2	2.52e-03	129	42	3	GO:0005262
GeneOntologyMolecularFunction	transcription regulator inhibitor activity	PURA PKD2	2.60e-03	36	42	2	GO:0140416
GeneOntologyMolecularFunction	monoatomic ion channel activity	SLC9C1 TRPC7 TRPC6 SCN7A PKD2	2.65e-03	459	42	5	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC9C1 TRPC7 TRPC6 SCN7A PKD2	2.80e-03	465	42	5	GO:0046873
GeneOntologyMolecularFunction	glycosyltransferase activity	UGT3A2 GALNT7 UGGT1 UGT3A1	3.08e-03	288	42	4	GO:0016757
GeneOntologyMolecularFunction	actinin binding	TRPC6 PKD2	3.69e-03	43	42	2	GO:0042805
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPC7 TRPC6 PKD2	3.92e-03	151	42	3	GO:0015085
GeneOntologyMolecularFunction	ADP binding	GLUD1 GLUD2	4.58e-03	48	42	2	GO:0043531
GeneOntologyMolecularFunction	sodium channel activity	SCN7A PKD2	5.36e-03	52	42	2	GO:0005272
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC9C1 SCN7A PKD2	5.55e-03	171	42	3	GO:0015081
GeneOntologyMolecularFunction	monoatomic cation channel activity	TRPC7 TRPC6 SCN7A PKD2	5.73e-03	343	42	4	GO:0005261
GeneOntologyBiologicalProcess	cellular response to hydroxyisoflavone	UGT3A2 UGT3A1	4.05e-06	2	42	2	GO:0071413
GeneOntologyBiologicalProcess	cellular response to genistein	UGT3A2 UGT3A1	4.05e-06	2	42	2	GO:0071412
GeneOntologyBiologicalProcess	cellular response to phenylpropanoid	UGT3A2 UGT3A1	4.05e-06	2	42	2	GO:1905546
GeneOntologyBiologicalProcess	response to genistein	UGT3A2 UGT3A1	1.21e-05	3	42	2	GO:0033595
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	BAX SLC9C1 TRPC7 GRID2IP TRPC6 SCN7A PLCE1 PKD2	2.75e-05	611	42	8	GO:0030003
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	BAX SLC9C1 TRPC7 GRID2IP TRPC6 SCN7A PLCE1 PKD2	3.12e-05	622	42	8	GO:0006873
GeneOntologyBiologicalProcess	response to hydroxyisoflavone	UGT3A2 UGT3A1	4.03e-05	5	42	2	GO:0033594
GeneOntologyBiologicalProcess	glutamate biosynthetic process	GLUD1 GLUD2	4.03e-05	5	42	2	GO:0006537
GeneOntologyBiologicalProcess	response to phenylpropanoid	UGT3A2 UGT3A1	6.04e-05	6	42	2	GO:0080184
GeneOntologyBiologicalProcess	response to aluminum ion	GLUD1 GLUD2	6.04e-05	6	42	2	GO:0010044
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	BAX SLC9C1 TRPC7 GRID2IP TRPC6 SCN7A PLCE1 PKD2	7.55e-05	705	42	8	GO:0055080
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	BAX TRPC7 GRID2IP TRPC6 PLCE1 PKD2	8.24e-05	359	42	6	GO:0006874
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	BAX SLC9C1 TRPC7 GRID2IP TRPC6 SCN7A PLCE1 PKD2	8.49e-05	717	42	8	GO:0050801
GeneOntologyBiologicalProcess	glutamate catabolic process	GLUD1 GLUD2	1.12e-04	8	42	2	GO:0006538
GeneOntologyBiologicalProcess	calcium ion homeostasis	BAX TRPC7 GRID2IP TRPC6 PLCE1 PKD2	1.28e-04	389	42	6	GO:0055074
GeneOntologyBiologicalProcess	inorganic ion homeostasis	BAX TRPC7 GRID2IP TRPC6 SCN7A PLCE1 PKD2	2.36e-04	622	42	7	GO:0098771
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	BAX SLC9C1 TRPC7 GRID2IP TRPC6 SCN7A PLCE1 PKD2	3.10e-04	866	42	8	GO:0055082
GeneOntologyBiologicalProcess	dicarboxylic acid biosynthetic process	GLUD1 GLUD2	4.77e-04	16	42	2	GO:0043650
GeneOntologyBiologicalProcess	protein heterotetramerization	RRM2 PKD2	4.77e-04	16	42	2	GO:0051290
GeneOntologyBiologicalProcess	tricarboxylic acid metabolic process	GLUD1 GLUD2	6.07e-04	18	42	2	GO:0072350
GeneOntologyBiologicalProcess	glutamine family amino acid biosynthetic process	GLUD1 GLUD2	6.07e-04	18	42	2	GO:0009084
GeneOntologyBiologicalProcess	regulation of cytosolic calcium ion concentration	TRPC7 GRID2IP TRPC6	6.67e-04	84	42	3	GO:0051480
GeneOntologyBiologicalProcess	cellular homeostasis	BAX SLC9C1 TRPC7 GRID2IP TRPC6 SCN7A PLCE1 PKD2	7.10e-04	981	42	8	GO:0019725
GeneOntologyBiologicalProcess	dicarboxylic acid catabolic process	GLUD1 GLUD2	7.51e-04	20	42	2	GO:0043649
GeneOntologyCellularComponent	UDP-N-acetylglucosamine transferase complex	UGT3A2 UGT3A1	2.25e-05	4	41	2	GO:0043541
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	4.70e-06	2	41	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	4.70e-06	2	41	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	4.70e-06	2	41	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	4.70e-06	2	41	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	4.70e-06	2	41	2	PF00208
Domain	ELFV_dehydrog	GLUD1 GLUD2	4.70e-06	2	41	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	4.70e-06	2	41	2	IPR033524
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	4.70e-06	2	41	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	4.70e-06	2	41	2	PS00074
Domain	SAA	SAA1 SAA2	2.81e-05	4	41	2	PS00992
Domain	SAA	SAA1 SAA2	2.81e-05	4	41	2	PF00277
Domain	SAA	SAA1 SAA2	2.81e-05	4	41	2	SM00197
Domain	Serum_amyloid_A	SAA1 SAA2	4.68e-05	5	41	2	IPR000096
Domain	TRP_dom	TRPC7 TRPC6	7.01e-05	6	41	2	IPR013555
Domain	TRP_2	TRPC7 TRPC6	7.01e-05	6	41	2	PF08344
Domain	TRPC_channel	TRPC7 TRPC6	9.81e-05	7	41	2	IPR002153
Domain	Ion_trans_dom	SLC9C1 TRPC7 TRPC6 SCN7A	1.12e-04	114	41	4	IPR005821
Domain	Ion_trans	SLC9C1 TRPC7 TRPC6 SCN7A	1.12e-04	114	41	4	PF00520
Domain	TRP_channel	TRPC7 TRPC6	2.55e-04	11	41	2	IPR004729
Domain	-	GALNT7 UAP1L1 UGGT1	7.44e-04	81	41	3	3.90.550.10
Domain	Nucleotide-diphossugar_trans	GALNT7 UAP1L1 UGGT1	9.47e-04	88	41	3	IPR029044
Domain	UDPGT	UGT3A2 UGT3A1	9.62e-04	21	41	2	PF00201
Domain	UDPGT	UGT3A2 UGT3A1	9.62e-04	21	41	2	PS00375
Domain	UDP_glucos_trans	UGT3A2 UGT3A1	9.62e-04	21	41	2	IPR002213
Domain	PDZ	DVL3 PTPN13 GRID2IP	3.64e-03	141	41	3	PF00595
Domain	PDZ	DVL3 PTPN13 GRID2IP	4.17e-03	148	41	3	SM00228
Domain	-	ASCC3 OTOF PLCE1	4.17e-03	148	41	3	2.60.40.150
Domain	-	DVL3 PTPN13 GRID2IP	4.33e-03	150	41	3	2.30.42.10
Domain	PDZ	DVL3 PTPN13 GRID2IP	4.41e-03	151	41	3	PS50106
Domain	PDZ	DVL3 PTPN13 GRID2IP	4.49e-03	152	41	3	IPR001478
Domain	C2_dom	ASCC3 OTOF PLCE1	5.55e-03	164	41	3	IPR000008
Domain	Channel_four-helix_dom	SCN7A PKD2	6.95e-03	57	41	2	IPR027359
Domain	-	SCN7A PKD2	6.95e-03	57	41	2	1.20.120.350
Domain	Ubiquitin-rel_dom	DVL3 PTPN13 PLCE1	7.62e-03	184	41	3	IPR029071
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	BAX TRPC7 TRPC6 PKD2	2.41e-07	44	42	4	19322198
Pubmed	Polymorphisms in the SAA1/2 gene are associated with carotid intima media thickness in healthy Han Chinese subjects: the Cardiovascular Risk Survey.	SAA1 SAA2	1.42e-06	2	42	2	21103356
Pubmed	The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis.	SAA1 SAA2	1.42e-06	2	42	2	26300108
Pubmed	DNA sequence evidence for polymorphic forms of human serum amyloid A (SAA).	SAA1 SAA2	1.42e-06	2	42	2	3800865
Pubmed	Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.42e-06	2	42	2	15750346
Pubmed	Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.	GLUD1 GLUD2	1.42e-06	2	42	2	1711373
Pubmed	Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.	GLUD1 GLUD2	1.42e-06	2	42	2	34173171
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	1.42e-06	2	42	2	28621566
Pubmed	Serum Amyloid A Promotes Inflammation-Associated Damage and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer.	SAA1 SAA2	1.42e-06	2	42	2	34217896
Pubmed	Serum amyloid A, an acute phase protein, inhibits platelet activation.	SAA1 SAA2	1.42e-06	2	42	2	1697614
Pubmed	Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.	SAA1 SAA2	1.42e-06	2	42	2	26937641
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	1.42e-06	2	42	2	32078638
Pubmed	Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.	GLUD1 GLUD2	1.42e-06	2	42	2	20529287
Pubmed	Serum amyloid A facilitates the binding of high-density lipoprotein from mice injected with lipopolysaccharide to vascular proteoglycans.	SAA1 SAA2	1.42e-06	2	42	2	21474830
Pubmed	Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.	GLUD1 GLUD2	1.42e-06	2	42	2	23595828
Pubmed	Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry).	GLUD1 GLUD2	1.42e-06	2	42	2	25124006
Pubmed	Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells.	SAA1 SAA2	1.42e-06	2	42	2	2890635
Pubmed	Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase.	GLUD1 GLUD2	1.42e-06	2	42	2	23673664
Pubmed	Influence of Serum Amyloid A (SAA1) and SAA2 gene polymorphisms on renal amyloidosis, and on SAA/C-reactive protein values in patients with familial mediterranean fever in the Turkish population.	SAA1 SAA2	1.42e-06	2	42	2	15170927
Pubmed	Acute-phase, but not constitutive serum amyloid A (SAA) is chemotactic for cultured human aortic smooth muscle cells.	SAA1 SAA2	1.42e-06	2	42	2	12557751
Pubmed	Serum amyloid alpha 1-2 are not required for liver inflammation in the 4T1 murine breast cancer model.	SAA1 SAA2	1.42e-06	2	42	2	36817472
Pubmed	Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.	SAA1 SAA2	1.42e-06	2	42	2	19729864
Pubmed	Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications.	SAA1 SAA2	1.42e-06	2	42	2	16737350
Pubmed	Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.	GLUD1 GLUD2	1.42e-06	2	42	2	21621574
Pubmed	Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.	GLUD1 GLUD2	1.42e-06	2	42	2	39052831
Pubmed	Murine apolipoprotein serum amyloid A in solution forms a hexamer containing a central channel.	SAA1 SAA2	1.42e-06	2	42	2	12456883
Pubmed	The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A.	SAA1 SAA2	1.42e-06	2	42	2	23431457
Pubmed	Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.	GLUD1 GLUD2	1.42e-06	2	42	2	24442550
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	1.42e-06	2	42	2	28911206
Pubmed	Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes.	UGT3A2 UGT3A1	1.42e-06	2	42	2	22621930
Pubmed	The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.	GLUD1 GLUD2	1.42e-06	2	42	2	27137930
Pubmed	Large-scale isotype-specific quantification of Serum amyloid A 1/2 by multiple reaction monitoring in crude sera.	SAA1 SAA2	1.42e-06	2	42	2	22300576
Pubmed	Extracellular matrix-anchored serum amyloid A preferentially induces mast cell adhesion.	SAA1 SAA2	1.42e-06	2	42	2	9252455
Pubmed	No evidence for a role of adipose tissue-derived serum amyloid a in the development of insulin resistance or obesity-related inflammation in hSAA1(+/-) transgenic mice.	SAA1 SAA2	1.42e-06	2	42	2	23967285
Pubmed	GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.	GLUD1 GLUD2	1.42e-06	2	42	2	26440896
Pubmed	Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity.	SAA1 SAA2	1.42e-06	2	42	2	25995210
Pubmed	Diversity and complexity of the mouse Saa1 and Saa2 genes.	SAA1 SAA2	1.42e-06	2	42	2	24521869
Pubmed	Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.	GLUD1 GLUD2	1.42e-06	2	42	2	22875990
Pubmed	Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.	GLUD1 GLUD2	1.42e-06	2	42	2	12742085
Pubmed	Linkage of protection against amyloid fibril formation in the mouse to a single, autosomal dominant gene.	SAA1 SAA2	1.42e-06	2	42	2	7760010
Pubmed	Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection.	SAA1 SAA2	1.42e-06	2	42	2	31819008
Pubmed	SAA does not induce cytokine production in physiological conditions.	SAA1 SAA2	1.42e-06	2	42	2	23165195
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	1.42e-06	2	42	2	15578726
Pubmed	Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis.	SAA1 SAA2	1.42e-06	2	42	2	1971508
Pubmed	Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.42e-06	2	42	2	15044002
Pubmed	Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.	SAA1 SAA2	1.42e-06	2	42	2	7561109
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	1.42e-06	2	42	2	22138648
Pubmed	Human serum amyloid A. Three hepatic mRNAs and the corresponding proteins in one person.	SAA1 SAA2	1.42e-06	2	42	2	3183061
Pubmed	Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.	GLUD1 GLUD2	1.42e-06	2	42	2	34220417
Pubmed	Complete primary structures of two major murine serum amyloid A proteins deduced from cDNA sequences.	SAA1 SAA2	1.42e-06	2	42	2	3857624
Pubmed	Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.	GLUD1 GLUD2	1.42e-06	2	42	2	26241911
Pubmed	A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells.	SAA1 SAA2	1.42e-06	2	42	2	9892621
Pubmed	Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.	GLUD1 GLUD2	1.42e-06	2	42	2	21446915
Pubmed	Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection.	GLUD1 GLUD2	1.42e-06	2	42	2	18688271
Pubmed	Impact of serum amyloid A on high density lipoprotein composition and levels.	SAA1 SAA2	1.42e-06	2	42	2	20667817
Pubmed	The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.	GLUD1 GLUD2	1.42e-06	2	42	2	22658952
Pubmed	Serum amyloid A protein induces production of matrix metalloproteinases by human synovial fibroblasts.	SAA1 SAA2	1.42e-06	2	42	2	9605178
Pubmed	Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2.	SAA1 SAA2	1.42e-06	2	42	2	23223242
Pubmed	GluD1 binds GABA and controls inhibitory plasticity.	GLUD1 GLUD2	1.42e-06	2	42	2	38060673
Pubmed	Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.	GLUD1 GLUD2	1.42e-06	2	42	2	24593767
Pubmed	Intestinal epithelial serum amyloid A modulates bacterial growth in vitro and pro-inflammatory responses in mouse experimental colitis.	SAA1 SAA2	1.42e-06	2	42	2	21067563
Pubmed	The human acute-phase serum amyloid A gene family: structure, evolution and expression in hepatoma cells.	SAA1 SAA2	1.42e-06	2	42	2	1656519
Pubmed	Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport.	GLUD1 GLUD2	1.42e-06	2	42	2	38124277
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	1.42e-06	2	42	2	37154294
Pubmed	Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.	GLUD1 GLUD2	1.42e-06	2	42	2	19015267
Pubmed	Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity.	SAA1 SAA2	1.42e-06	2	42	2	32572240
Pubmed	Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.	GLUD1 GLUD2	1.42e-06	2	42	2	22924626
Pubmed	Effect of serum amyloid A on selected in vitro functions of isolated human neutrophils.	SAA1 SAA2	1.42e-06	2	42	2	9823935
Pubmed	AA amyloidosis-resistant CE/J mice have Saa1 and Saa2 genes that encode an identical SAA isoform.	SAA1 SAA2	1.42e-06	2	42	2	24228751
Pubmed	The frequencies of the serum amyloid A2 alleles in healthy (Turkish, Azerbaijan and Kazakh) populations.	SAA1 SAA2	1.42e-06	2	42	2	16152805
Pubmed	Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.	GLUD1 GLUD2	1.42e-06	2	42	2	19448744
Pubmed	Differential glucocorticoid enhancement of the cytokine-driven transcriptional activation of the human acute phase serum amyloid A genes, SAA1 and SAA2.	SAA1 SAA2	1.42e-06	2	42	2	12077270
Pubmed	A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion.	SAA1 SAA2	1.42e-06	2	42	2	7636186
Pubmed	Regulation of the human acute phase serum amyloid A genes by tumour necrosis factor-alpha, interleukin-6 and glucocorticoids in hepatic and epithelial cell lines.	SAA1 SAA2	1.42e-06	2	42	2	14871291
Pubmed	Defining lipid-binding regions of human serum amyloid A using its fragment peptides.	SAA1 SAA2	1.42e-06	2	42	2	19665458
Pubmed	Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.	GLUD1 GLUD2	1.42e-06	2	42	2	11032875
Pubmed	Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.	TRPC7 TRPC6	1.42e-06	2	42	2	23529130
Pubmed	Isolation and purification of two major serum amyloid A isotypes SAA1 and SAA2 from the acute phase plasma of mice.	SAA1 SAA2	1.42e-06	2	42	2	9518179
Pubmed	Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.	GLUD1 GLUD2	1.42e-06	2	42	2	11950837
Pubmed	Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.	GLUD1 GLUD2	1.42e-06	2	42	2	29943084
Pubmed	Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes.	TRPC6 PLCE1	1.42e-06	2	42	2	25521631
Pubmed	Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes.	SAA1 SAA2	1.42e-06	2	42	2	7516407
Pubmed	Structural prerequisites for serum amyloid A fibril formation.	SAA1 SAA2	1.42e-06	2	42	2	8376413
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	1.42e-06	2	42	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	1.42e-06	2	42	2	15378063
Pubmed	Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.	GLUD1 GLUD2	1.42e-06	2	42	2	27422263
Pubmed	PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels.	TRPC7 TRPC6	1.42e-06	2	42	2	24470487
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	VAV3 HMGCS1 SEC23B UGGT1 GLUD1 GLUD2	3.48e-06	344	42	6	30333137
Pubmed	The human serum amyloid A protein (SAA) superfamily gene cluster: mapping to chromosome 11p15.1 by physical and genetic linkage analysis.	SAA1 SAA2	4.27e-06	3	42	2	8188252
Pubmed	Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.	GLUD1 GLUD2	4.27e-06	3	42	2	29784783
Pubmed	SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.	SAA1 SAA2	4.27e-06	3	42	2	34597680
Pubmed	Serum amyloid A3 is a high density lipoprotein-associated acute-phase protein.	SAA1 SAA2	4.27e-06	3	42	2	29247043
Pubmed	Diverse gene expression for isotypes of murine serum amyloid A protein during acute phase reaction.	SAA1 SAA2	4.27e-06	3	42	2	3456645
Pubmed	Structure of the murine serum amyloid A gene family. Gene conversion.	SAA1 SAA2	4.27e-06	3	42	2	3013853
Pubmed	High-density lipoprotein inhibits serum amyloid A-mediated reactive oxygen species generation and NLRP3 inflammasome activation.	SAA1 SAA2	4.27e-06	3	42	2	29976759
Pubmed	Serum Amyloid A Is an Exchangeable Apolipoprotein.	SAA1 SAA2	4.27e-06	3	42	2	29976766
Pubmed	The structure of apo human glutamate dehydrogenase details subunit communication and allostery.	GLUD1 GLUD2	4.27e-06	3	42	2	12054821
Pubmed	Serum amyloid A stimulates lipoprotein-associated phospholipase A2 expression in vitro and in vivo.	SAA1 SAA2	4.27e-06	3	42	2	23623642
Pubmed	Impact of individual acute phase serum amyloid A isoforms on HDL metabolism in mice.	SAA1 SAA2	4.27e-06	3	42	2	27018443
Pubmed	Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I.	SAA1 SAA2	4.27e-06	3	42	2	16120612
Cytoband	5p13.2	UGT3A2 UGT3A1	3.74e-04	31	42	2	5p13.2
GeneFamily	Transient receptor potential cation channels	TRPC7 TRPC6 PKD2	9.49e-06	28	27	3	249
GeneFamily	UDP glucuronosyltransferases	UGT3A2 UGT3A1	1.04e-03	32	27	2	363
GeneFamily	PDZ domain containing	DVL3 PTPN13 GRID2IP	1.47e-03	152	27	3	1220
GeneFamily	PHD finger proteins	TRIM28 CHD5	7.93e-03	90	27	2	88
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HMGCS1 PTPN13 VCAN TRPC6 SCN7A	8.83e-07	187	42	5	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 TRPC6 PKD2	1.27e-05	152	42	4	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 TRPC6 PKD2	1.27e-05	152	42	4	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VAV3 TRPC6 SCN7A PLCE1	2.52e-05	181	42	4	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_1\|COVID-19_Severe / Disease condition and Cell class	HACD4 OTOF VCAN GLUD2	2.52e-05	181	42	4	0d07a67e8ee3bca687b378afbc4044434e63556d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VAV3 GALNT7 SCN7A PLCE1	2.63e-05	183	42	4	121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VAV3 GALNT7 SCN7A PLCE1	2.92e-05	188	42	4	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	facs-Skin-Anagen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DVL3 HMGCS1 TRIM28 PURA	3.04e-05	190	42	4	888ded899f0513d41bf655896d59ae8ef74e0978
ToppCell	facs-Skin-Anagen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DVL3 HMGCS1 TRIM28 PURA	3.04e-05	190	42	4	3466cebab16964e94da130d0673fa32e7d90b5ed
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	ZDHHC20 VAV3 OTOF VCAN	3.50e-05	197	42	4	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VCAN TRPC6 SCN7A PKD2	3.72e-05	200	42	4	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-LGR5--L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	VAV3 TRPC6 SCN7A PLCE1	3.72e-05	200	42	4	8c1d4fffa5abe89ee2ff84fed2dfa97c779bde04
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-LGR5-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	VAV3 TRPC6 SCN7A PLCE1	3.72e-05	200	42	4	1026b4ede4ea61d01ea942164b37a08c8c8234ff
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VCAN TRPC6 SCN7A PKD2	3.72e-05	200	42	4	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SAA1 SAA2 GALNT7 PYROXD1	3.72e-05	200	42	4	68b0f987c4fb8078675475f4f1e71302f832ef69
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SAA1 SAA2 GALNT7 PYROXD1	3.72e-05	200	42	4	1b527bebbca1ef8c52449e40beb9358e37494e04
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-LGR5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	VAV3 TRPC6 SCN7A PLCE1	3.72e-05	200	42	4	72c9cd872074b60f62685a95eab83c41e609eb6e
ToppCell	LPS_only-Unknown\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9C1 TRPC6 PLCE1	1.74e-04	115	42	3	7a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCell	LPS_only-Unknown-Endothelial-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9C1 TRPC6 PLCE1	1.74e-04	115	42	3	c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCell	LPS_only-Unknown-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9C1 TRPC6 PLCE1	1.74e-04	115	42	3	ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCell	TCGA-Brain-Recurrent_Tumor-Glioblastoma\|TCGA-Brain / Sample_Type by Project: Shred V9	SAA1 SAA2 RAB27A	2.97e-04	138	42	3	142e4692d7f97ce157ed70fcb2e4a63febfbb6e4
ToppCell	TCGA-Brain-Recurrent_Tumor-Glioblastoma-Primary_GBM\|TCGA-Brain / Sample_Type by Project: Shred V9	SAA1 SAA2 RAB27A	2.97e-04	138	42	3	728e0576526c4525ba2038921425ab3e7d321ce2
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 VAV3	3.50e-04	146	42	3	74009a2921359a8352afbaea8c325a3743622543
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 VAV3	3.50e-04	146	42	3	cb19f2bb6832d11fe69b670df49eac096a378a9d
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 RAB27A	3.64e-04	148	42	3	f58804d24fe524b42b5090c8658050ea4b14793e
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 RAB27A	3.64e-04	148	42	3	941bad657064b3d37cae8b66df99c1aa1098c088
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GRID2IP SCN7A PLCE1	3.72e-04	149	42	3	98ae408d2d0347865875ff8bbd89d359decea526
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	CENPP VCAN SCN7A	3.72e-04	149	42	3	3904f8ce9078de238600ceceee0116af52256a1c
ToppCell	droplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	3.86e-04	151	42	3	cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRM2 SLC22A14 UGT3A1	4.09e-04	154	42	3	46155f36d3983f637b55d7525b675c8828f6ab2e
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRM2 SLC22A14 UGT3A1	4.09e-04	154	42	3	71ffc23a2e02e27cabbdbeaa622e59e9f4a4cd9d
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SAA1 SAA2 PLCE1	4.17e-04	155	42	3	d8b5145258f075b15080f8739f537f48dd22225e
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SAA1 SAA2 PLCE1	4.17e-04	155	42	3	ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SAA1 SAA2 PLCE1	4.17e-04	155	42	3	0f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 RAB27A	4.49e-04	159	42	3	c9e093d7c1dca83f6546adaf3d874929e2cea612
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SAA2 RAB27A PKD2	4.58e-04	160	42	3	8bb873704895c3b35bba8af78fedbabf7df42e71
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SLC9C1 UGT3A2	4.66e-04	161	42	3	b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SLC9C1 UGT3A2	4.66e-04	161	42	3	f7a89c481f789f624102857be722c95fbeb47595
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT3A2 SLC22A14 UGT3A1	4.75e-04	162	42	3	de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SAA1 SAA2 GRID2IP	4.92e-04	164	42	3	76b0ac220b7ca22fbea28a507f01f96ae9f53932
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SAA1 SAA2 GRID2IP	4.92e-04	164	42	3	911081739174ec68bc0893c804e4276b206bea7d
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SAA1 SAA2 GRID2IP	4.92e-04	164	42	3	c5bfae7e9497185548c243d6f9ebadbcef48ba7f
ToppCell	facs-Marrow-T_cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HACD4 SAA1 SAA2	5.09e-04	166	42	3	fab4da2537904ad114218f720e18a600f14a00a1
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	VAV3 UAP1L1 RAB27A	5.18e-04	167	42	3	ded4d6cccd3660662f12cf5a512de31d26325f1b
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HACD4 OTOF VCAN	5.27e-04	168	42	3	f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC6 SCN7A PLCE1	5.27e-04	168	42	3	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC6 SCN7A PLCE1	5.27e-04	168	42	3	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	facs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	5.37e-04	169	42	3	922086f218135b734b7d370b871923e50141edce
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	PTPN13 SCN7A PLCE1	5.37e-04	169	42	3	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPP RRM2 VCAN	5.37e-04	169	42	3	563c267edaade0e5df192ad953801ef9768d4270
ToppCell	facs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	5.37e-04	169	42	3	ee27bcfe3f9a295ec5fb0a375d77d1050e5cbaad
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC7 TRPC6 PLCE1	5.46e-04	170	42	3	45584bd9953257dd28c06ffbbfe4395ce7b1b88d
ToppCell	droplet-Kidney-nan-3m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	5.46e-04	170	42	3	dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SAA2 RAB27A TRPC6	5.55e-04	171	42	3	a6ed4d5b9d552017dd0958face45167e93cf3e8c
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC9C1 TRPC6 OXGR1	5.55e-04	171	42	3	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	droplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	5.55e-04	171	42	3	05fcc72df50a380a913821b5781d9621df37d328
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	5.55e-04	171	42	3	48fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HACD4 SAA1 SAA2	5.74e-04	173	42	3	0f9784b30c81a4a4940e0623cec60d596e9985d2
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HACD4 SAA1 SAA2	5.74e-04	173	42	3	60f79e0698a7cf7516690fb20f1b82ee46547699
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SAA1 SAA2 TRPC6	5.84e-04	174	42	3	e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC6 SCN7A PLCE1	5.84e-04	174	42	3	cc4c7f00a25a7814b52d4599166615daa140cc31
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 RAB27A	5.84e-04	174	42	3	d927504d27b07bbc580bf57c60b383bd28624652
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal-GABAergic_neurons\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SAA2 VAV3 OXGR1	5.94e-04	175	42	3	d4ff1f197ad4086286e86817cbff24fa718293fc
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_1\|Classical_Monocyte / Disease condition and Cell class	HACD4 OTOF GLUD2	5.94e-04	175	42	3	35ea2ed93538e6bf803029fcf7d9243f93e7733d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VAV3 TRPC7 OXGR1	5.94e-04	175	42	3	576d472f078486ee8403ca93b43a26bda88b1b8a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VAV3 SCN7A PLCE1	5.94e-04	175	42	3	29a4197ad4b2382257d7cc9ff237726bb60bc06d
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HACD4 VCAN GLUD1	6.04e-04	176	42	3	1bf8fed48bd224f09efe90a38233b1f01d7311fe
ToppCell	facs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A14 TRPC6 PLCE1	6.14e-04	177	42	3	1b153fbfe1323dc589de4af73a52149ea5ce6763
ToppCell	ASK428-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	SAA1 SAA2 VAV3	6.14e-04	177	42	3	66074a288501c136b4e83b883db5f0d8269ee326
ToppCell	facs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A14 TRPC6 PLCE1	6.14e-04	177	42	3	32fecefba1a55e1f418c9a055236fa11175c692d
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RRM2 CHD5 TMEM135	6.14e-04	177	42	3	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRM2 CLEC16A OXGR1	6.24e-04	178	42	3	de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HACD4 SLC22A14 PLCE1	6.24e-04	178	42	3	1e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 GALNT7 RAB27A	6.24e-04	178	42	3	07d6d5275a4d17f8024fde74e92ab2505b4adfbf
ToppCell	Dividing_Macrophages-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	HACD4 SAA1 RRM2	6.24e-04	178	42	3	6557688c6790a5bcc3b9aea5b8789cf9506b3c54
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HACD4 VCAN GLUD1	6.34e-04	179	42	3	fa58fa0901eadb170e3d2facb2a3d8c5e624329a
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HACD4 VCAN GLUD1	6.34e-04	179	42	3	66afd54428e6dcadc3e341faecfde42be4fb5905
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD5 SCN7A PLCE1	6.34e-04	179	42	3	c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VAV3 SCN7A PLCE1	6.34e-04	179	42	3	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	VAV3 RRM2 SCN7A	6.34e-04	179	42	3	d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PYROXD1 UAP1L1 TMEM135	6.45e-04	180	42	3	be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 CHD5 SCN7A	6.45e-04	180	42	3	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAA1 SAA2 RAB27A	6.45e-04	180	42	3	a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PYROXD1 UAP1L1 TMEM135	6.45e-04	180	42	3	3b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HACD4 SLC22A14 PLCE1	6.45e-04	180	42	3	2ccc77d769d3ffd77ab3af45e4f192785b6db79c
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 CHD5 SCN7A	6.45e-04	180	42	3	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	Mesenchymal_cells-Stromal_fibro.\|Mesenchymal_cells / Lineage and Cell class	SAA1 SAA2 SCN7A	6.55e-04	181	42	3	f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCell	droplet-Kidney-KIDNEY\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	6.55e-04	181	42	3	3a8c2bc0199b8fe2235ada14672bd31153d5a682
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRPC6 SCN7A PLCE1	6.55e-04	181	42	3	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 GALNT7 UGT3A1	6.55e-04	181	42	3	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC9C1 ASCC3 CLEC16A	6.55e-04	181	42	3	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	RA-16._Neuronal\|World / Chamber and Cluster_Paper	PTPN13 SCN7A PLCE1	6.55e-04	181	42	3	7d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPP RRM2 UGGT1	6.66e-04	182	42	3	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	6.66e-04	182	42	3	bdeebbfffc1308a29b721a5f8fed23a28d7a2f2f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC6 SCN7A PLCE1	6.66e-04	182	42	3	d4cb23b5a974c096a0ce84b47fe351eef44894d7
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCS1 UGT3A2 UGT3A1	6.66e-04	182	42	3	be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VAV3 SCN7A PLCE1	6.66e-04	182	42	3	a3c5c0eff527c8d3848acda14af8f9e99c69b0de
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VCAN SCN7A PKD2	6.66e-04	182	42	3	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 CHD5 SCN7A	6.66e-04	182	42	3	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 CHD5 SCN7A	6.66e-04	182	42	3	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
Drug	UDP-N-acetylglucosamine	GALNT7 UAP1L1 UGGT1 UGT3A1 GLUD1 GLUD2	1.62e-06	203	41	6	CID000001167
Drug	silver nitrate	SAA1 SAA2 GLUD1 GLUD2	1.81e-06	49	41	4	CID000024470
Drug	phenyltriethoxysilane	GLUD1 GLUD2	3.16e-06	2	41	2	CID000013075
Drug	methylmercuric bromide	GLUD1 GLUD2	3.16e-06	2	41	2	CID000068175
Drug	5-methylisophthalate	GLUD1 GLUD2	3.16e-06	2	41	2	CID000068137
Drug	G-3SH	GLUD1 GLUD2	3.16e-06	2	41	2	CID000174237
Drug	x 1 s	GLUD1 GLUD2	3.16e-06	2	41	2	CID000409694
Drug	iodoacetyldiethylstilbestrol	GLUD1 GLUD2	3.16e-06	2	41	2	CID006455327
Drug	ML 9	BAX TRPC7 TRPC6	5.15e-06	19	41	3	ctd:C056218
Drug	methoxyethylmercury	GLUD1 GLUD2	9.48e-06	3	41	2	CID000115155
Drug	4-methylumbelliferyl laurate	GLUD1 GLUD2	9.48e-06	3	41	2	CID000600674
Drug	methylmercuric iodide	GLUD1 GLUD2	9.48e-06	3	41	2	CID000067347
Drug	lenthionine	GLUD1 GLUD2	9.48e-06	3	41	2	CID000067521
Drug	mildiomycin	GLUD1 GLUD2	9.48e-06	3	41	2	CID000125665
Drug	methyl benzoquate	GLUD1 GLUD2	1.89e-05	4	41	2	CID000026383
Drug	8-BDB-TADP	GLUD1 GLUD2	1.89e-05	4	41	2	CID000130791
Drug	cadina-3,9-diene	GLUD1 GLUD2	1.89e-05	4	41	2	CID000010657
Drug	AC1L9CUQ	GLUD1 GLUD2	1.89e-05	4	41	2	CID000442451
Drug	pentenoic acid	GLUD1 GLUD2	1.89e-05	4	41	2	CID000012299
Drug	alpha-ketoglutaramate	GLUD1 GLUD2	1.89e-05	4	41	2	CID000000048
Drug	luxabendazole	GLUD1 GLUD2	1.89e-05	4	41	2	CID000072019
Drug	ureidoglycine	GLUD1 GLUD2	1.89e-05	4	41	2	CID000439649
Drug	N-butylmaleimide	GLUD1 GLUD2	1.89e-05	4	41	2	CID000239780
Drug	Ivin	GLUD1 GLUD2	1.89e-05	4	41	2	CID000014083
Drug	alpha-methylglutamate	GLUD1 GLUD2	1.89e-05	4	41	2	CID000095440
Drug	2b E2	GLUD1 GLUD2	1.89e-05	4	41	2	CID005327076
Drug	benzamide riboside	BAX GLUD1 GLUD2	2.35e-05	31	41	3	CID000122749
Drug	1-pheg	GLUD1 GLUD2	3.15e-05	5	41	2	CID000152041
Drug	5'-FSBAzA	GLUD1 GLUD2	3.15e-05	5	41	2	CID000130430
Drug	adenine N1-oxide	GLUD1 GLUD2	3.15e-05	5	41	2	CID000093557
Drug	bathocuproine	GLUD1 GLUD2	3.15e-05	5	41	2	CID000065149
Drug	choline sulfate	GLUD1 GLUD2	3.15e-05	5	41	2	CID000000485
Drug	l-413	GLUD1 GLUD2	3.15e-05	5	41	2	CID000012475
Drug	AC1NRA4I	GLUD1 GLUD2	3.15e-05	5	41	2	CID005287695
Drug	isosteviol lactone	GLUD1 GLUD2	3.15e-05	5	41	2	CID000401559
Drug	3-aminopicolinate	GLUD1 GLUD2	3.15e-05	5	41	2	CID000073836
Drug	Zeranol	BAX TRPC6 PKD2	3.41e-05	35	41	3	ctd:D015029
Drug	Paclitaxel	BAX PTPN13 RRM2 GALNT7 VCAN TMEM135 PLCE1 PKD2	3.65e-05	720	41	8	ctd:D017239
Drug	alpha-monofluoromethylputrescine	GLUD1 GLUD2	4.72e-05	6	41	2	CID000134201
Drug	dadAB	GLUD1 GLUD2	4.72e-05	6	41	2	CID000022626
Drug	N-methylhydantoin	GLUD1 GLUD2	4.72e-05	6	41	2	CID000069217
Drug	diazonium-1-H-tetrazole	GLUD1 GLUD2	4.72e-05	6	41	2	CID000188312
Drug	AC1L448Y	GLUD1 GLUD2	4.72e-05	6	41	2	CID000200389
Drug	2-BDB-TAMP	GLUD1 GLUD2	4.72e-05	6	41	2	CID000127220
Drug	Emid	GLUD1 GLUD2	4.72e-05	6	41	2	CID000074798
Drug	dimethylmalonate	GLUD1 GLUD2	4.72e-05	6	41	2	CID000007943
Drug	AC1L8SA5	GLUD1 GLUD2	4.72e-05	6	41	2	CID000407285
Drug	2-methyl-1,2,3,4-tetrahydroisoquinoline	GLUD1 GLUD2	4.72e-05	6	41	2	CID000015362
Drug	lanosol	GLUD1 GLUD2	4.72e-05	6	41	2	CID000078659
Drug	isodiazinon	GLUD1 GLUD2	4.72e-05	6	41	2	CID000133913
Drug	AC1Q5V97	PURA GLUD1 GLUD2	6.36e-05	43	41	3	CID000000195
Drug	carbophenothion	GLUD1 GLUD2	6.61e-05	7	41	2	CID000013081
Drug	37474A	GLUD1 GLUD2	6.61e-05	7	41	2	CID004330138
Drug	AC1L1B5W	GLUD1 GLUD2	6.61e-05	7	41	2	CID000001296
Drug	baricitinib	SAA1 SAA2	6.61e-05	7	41	2	ctd:C000596027
Drug	2-oxoglutaconic acid	GLUD1 GLUD2	6.61e-05	7	41	2	CID006443759
Drug	d-serine methyl ester hydrochloride	GLUD1 GLUD2	6.61e-05	7	41	2	CID000090387
Drug	6-chloroquinoxaline-2,3-diol	GLUD1 GLUD2	8.80e-05	8	41	2	CID000081143
Drug	2-heptanol	GLUD1 GLUD2	8.80e-05	8	41	2	CID000010976
Drug	2'(3')-O-(2,4,6-trinitrophenyl)-ADP	GLUD1 GLUD2	8.80e-05	8	41	2	CID000644359
Drug	Nessler's reagent	GLUD1 GLUD2	8.80e-05	8	41	2	CID000024542
Drug	iminoglutarate	GLUD1 GLUD2	8.80e-05	8	41	2	CID000152649
Drug	bidisomide	GLUD1 GLUD2	8.80e-05	8	41	2	CID000059798
Drug	Pheg	GLUD1 GLUD2	8.80e-05	8	41	2	CID003080746
Drug	AC1MQ2IK	GLUD1 GLUD2	8.80e-05	8	41	2	CID003394958
Drug	AC1N690Y	GLUD1 GLUD2	8.80e-05	8	41	2	CID004256264
Drug	trimethyllead chloride	GLUD1 GLUD2	8.80e-05	8	41	2	CID000223969
Drug	doxifluridine	PTPN13 PLCE1 PKD2	1.00e-04	50	41	3	ctd:C025034
Drug	NHS-ASA	GLUD1 GLUD2	1.13e-04	9	41	2	CID003035647
Drug	dimethyl L-glutamate	GLUD1 GLUD2	1.13e-04	9	41	2	CID000093032
Drug	AC1L1GWH	GLUD1 GLUD2	1.13e-04	9	41	2	CID000003872
Drug	AC1N4HBY	GLUD1 GLUD2	1.13e-04	9	41	2	CID004128835
Drug	DCQX	GLUD1 GLUD2	1.13e-04	9	41	2	CID000001845
Drug	adipamide	GLUD1 GLUD2	1.13e-04	9	41	2	CID000012364
Drug	temelastine	GLUD1 GLUD2	1.13e-04	9	41	2	CID000055482
Drug	Asparagusate	GLUD1 GLUD2	1.13e-04	9	41	2	CID000016682
Drug	tripterine	BAX HMGCS1 RRM2 PURA	1.13e-04	139	41	4	ctd:C050414
Drug	isovaleryl-CoA	HMGCS1 GLUD1 GLUD2	1.19e-04	53	41	3	CID000000810
Drug	1,2-dioleoyloxy-3-(trimethylammonium)propane	SAA1 SAA2 OTOF	1.26e-04	54	41	3	ctd:C070046
Drug	AC1O592B	RRM2 RAB27A	1.41e-04	10	41	2	CID006480203
Drug	bis-NAD	GLUD1 GLUD2	1.41e-04	10	41	2	CID003081557
Drug	NmiQ	GLUD1 GLUD2	1.41e-04	10	41	2	CID000019850
Drug	S884	GLUD1 GLUD2	1.41e-04	10	41	2	CID004685067
Drug	diglycerol	GLUD1 GLUD2	1.41e-04	10	41	2	CID000042953
Drug	Capecitabine	PTPN13 PLCE1 PKD2	1.48e-04	57	41	3	ctd:D000069287
Drug	mono-(2-ethylhexyl)phthalate	BAX HMGCS1 ASCC3 GALNT7 UAP1L1 RAB27A CHD5	1.56e-04	658	41	7	ctd:C016599
Drug	sulfoacetic acid	GLUD1 GLUD2	1.72e-04	11	41	2	CID000031257
Drug	ADP-ribosylcysteine	GLUD1 GLUD2	1.72e-04	11	41	2	CID003035804
Drug	5-ethylphenazin-5-ium	GLUD1 GLUD2	1.72e-04	11	41	2	CID000082689
Drug	kievitone	GLUD1 GLUD2	1.72e-04	11	41	2	CID000119269
Drug	AC1O3MP2	GLUD1 GLUD2	1.72e-04	11	41	2	CID006332324
Drug	o-diazoacetyl-L-serine	VCAN GLUD1 GLUD2	1.90e-04	62	41	3	CID000000830
Drug	Manganese	BAX SAA1 TRPC6 GLUD1 SCN7A PLCE1	2.05e-04	480	41	6	ctd:D008345
Drug	anisylamine	BAX VCAN	2.06e-04	12	41	2	CID000075452
Drug	Methylthioacetylaminoethanol	GLUD1 GLUD2	2.06e-04	12	41	2	CID000155653
Drug	2-aminoethyl diphenylborinate	BAX TRPC6	2.06e-04	12	41	2	ctd:C538758
Drug	nitroparacetamol	GLUD1 GLUD2	2.06e-04	12	41	2	CID006918532
Drug	5'-deoxypyridoxal	GLUD1 GLUD2	2.06e-04	12	41	2	CID000164889
Drug	AC1O3Q5W	GLUD1 GLUD2	2.06e-04	12	41	2	CID006334250
Drug	gabapentin	GLUD1 GLUD2 SCN7A PKD2	2.39e-04	169	41	4	CID000003446
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	5.65e-06	3	41	2	DOID:885 (biomarker_via_orthology)
Disease	X-24544 measurement	UGT3A2 UGT3A1	1.13e-05	4	41	2	EFO_0800892
Disease	nephrotic syndrome type 2 (is_implicated_in)	TRPC6 PLCE1	1.13e-05	4	41	2	DOID:0080379 (is_implicated_in)
Disease	serum amyloid A protein measurement	SAA1 SAA2	2.82e-05	6	41	2	EFO_0004728
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	2.82e-05	6	41	2	DOID:1825 (biomarker_via_orthology)
Disease	intracranial aneurysm (is_implicated_in)	VCAN PKD2	1.23e-04	12	41	2	DOID:10941 (is_implicated_in)
Disease	nicotine dependence (implicated_via_orthology)	TRPC7 TRPC6	1.23e-04	12	41	2	DOID:0050742 (implicated_via_orthology)
Disease	hepatic encephalopathy (biomarker_via_orthology)	GLUD1 GLUD2	1.96e-04	15	41	2	DOID:13413 (biomarker_via_orthology)
Disease	functional brain measurement	VCAN TRPC6 PLCE1	2.04e-04	82	41	3	EFO_0007849
Disease	serum amyloid A-1 protein measurement	SAA1 SAA2	2.84e-04	18	41	2	EFO_0008282
Disease	Renal glomerular disease	TRPC6 PLCE1	4.68e-04	23	41	2	C0268731
Disease	Glomerulopathy Assessment	TRPC6 PLCE1	4.68e-04	23	41	2	C4521256
Disease	Lewy body dementia, Lewy body dementia measurement	SAA1 SAA2	5.99e-04	26	41	2	EFO_0006792, EFO_0006799
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	TRPC6 PLCE1	7.99e-04	30	41	2	C1868672
Disease	temporal lobe epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	8.54e-04	31	41	2	DOID:3328 (biomarker_via_orthology)
Disease	asthma, seasonal allergic rhinitis	VAV3 CLEC16A	9.10e-04	32	41	2	EFO_0003956, MONDO_0004979
Disease	Facial wrinkling	HACD4 VAV3	1.22e-03	37	41	2	HP_0009762
Disease	biliary liver cirrhosis	CLEC16A UGT3A1	1.72e-03	44	41	2	EFO_0004267
Disease	Familial thoracic aortic aneurysm and aortic dissection	VCAN PKD2	2.48e-03	53	41	2	C4707243

Protein segments in the cluster

Peptide	Gene	Start	Entry
FLARAYGFEMAKEFV	VCAN	2401	P13611
FKFMFNIADGGFTEL	CHD5	1701	Q8TDI0
SYKFFFKSMDDDFGV	DVL3	41	Q92997
KDLFMFFRSLHFFVE	CENPP	161	Q6IPU0
KDFTLNDFGFMIFHS	HMGCS1	251	Q01581
TAFFRDAMGFLLLFD	RAB27A	86	P51159
RFFSFGKDSMVDTFY	HACD4	41	Q5VWC8
FVLMPFAFFFLESEG	LMBR1	121	Q8WVP7
FGDFMCKFIRFSFHF	OXGR1	101	Q96P68
FFGIFAEFMSKFERA	GRID2IP	1176	A4D2P6
FFKMVEGFFDRGASI	GLUD1	66	P00367
AMAGGLFAIEREFFF	GALNT7	386	Q86SF2
VFFRVAADMFSDGNF	BAX	91	Q07812
AFFMFADHFVFTAQK	SLC22A14	81	Q9Y267
FFKMVEGFFDRGASI	GLUD2	66	P49448
KMEEFFLFGAFLEAS	OTOF	606	Q9HC10
TVNFTLFFRIKFFMD	PTPN13	651	Q12923
FMAVTEFTFEGFSIF	OR10J4	6	P0C629
FFLMFGDLDSFFLAA	OR1N1	101	Q8NGS0
FFSFLGEAFDGARDM	SAA2	21	P0DJI9
MAGIFKEFFFSTEDL	SLC9C1	1	Q4G0N8
SFEGFARFLMDKENF	PLCE1	1366	Q9P212
AAVFFNMGIDFRSLF	SLF2	856	Q8IX21
IFTKDFNGDFRMAFG	SEC23B	391	Q15437
FFSFLGEAFDGARDM	SAA1	21	P0DJI8
VFFGKNLAFSFDMHD	ASCC3	161	Q8N3C0
SSVFDFFLEKNMFVF	CLEC16A	66	Q2KHT3
DFWGRVKNFLMFFSF	UGT3A1	196	Q6NUS8
AKFHVLFLFFVSAMF	ZDHHC20	206	Q5W0Z9
MDFSFELFAHVTKFF	PYROXD1	401	Q8WU10
GFSKVFRVENPFDFM	RRM2	336	P31350
MFFFRCKDGLKGFTF	TMEM135	166	Q86UB9
MEKFVFDVFRFAKNF	UAP1L1	381	Q3KQV9
SRCAKDLFGFAIMFF	PKD2	591	Q13563
TFIFFSAAFGMKLFG	SCN7A	636	Q01118
FGMLAIFAASFIARF	TRPC6	531	Q9Y210
DFWGRVKNFLMFFSF	UGT3A2	196	Q3SY77
FFFDVGSNKYGVFMR	PURA	231	Q00577
FSVGGMDFSLFKEVF	UGGT1	851	Q9NYU2
FFETRMNEAFGDTKF	TRIM28	791	Q13263
IFVASFTARFMAFLK	TRPC7	481	Q9HCX4
FGMRKSELFEAFDLF	VAV3	86	Q9UKW4