Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmesenchyme migration

ACTA1 ACTA2 ACTC1 ACTG2

5.80e-0951224GO:0090131
GeneOntologyBiologicalProcesstissue morphogenesis

VEGFC FAT4 RARG ACTA1 ACTA2 FIGNL2 SOX17 PDX1 DAG1 ACTC1 ACTG2 IRX3 ITGA5 STAT5A PGR HOXB2 LLGL2 BRSK1 TCTN1

8.72e-0875012219GO:0048729
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

VEGFC FAT4 RARG FIGNL2 SOX17 PDX1 DAG1 IRX3 ITGA5 STAT5A PGR HOXB2 LLGL2 BRSK1 TCTN1

3.87e-0661912215GO:0002009
GeneOntologyBiologicalProcessanimal organ morphogenesis

VEGFC FAT4 RARG UNCX ACTA1 NACA ACTA2 SOX17 PDX1 DAG1 ACTC1 ACTG2 TMEM119 IRX3 PPP1R13L MMP20 STAT5A PGR HOXB2 THBS1 ACP4

1.64e-05126912221GO:0009887
GeneOntologyCellularComponentfilopodium

ACTA1 ACTA2 DAG1 ACTC1 ACTG2 ADGRA2

1.02e-041231266GO:0030175
GeneOntologyCellularComponentactin-based cell projection

AMN ACTA1 ACTA2 DAG1 ACTC1 ACTG2 ADGRA2 FMN2

2.87e-042781268GO:0098858
DomainActin_CS

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

3.98e-08161195IPR004001
DomainACTINS_2

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

5.62e-08171195PS00432
DomainActin/actin-like_CS

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

7.74e-08181195IPR020902
DomainACTINS_ACT_LIKE

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

1.04e-07191195PS01132
DomainACTINS_1

ACTA1 ACTA2 ACTC1 ACTG2

1.08e-0781194PS00406
DomainActin

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

1.44e-06311195IPR004000
DomainActin

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

1.44e-06311195PF00022
DomainACTIN

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

1.44e-06311195SM00268
DomainLLGL

STXBP5 LLGL2

2.40e-0441192PF08366
DomainLethal2_giant

STXBP5 LLGL2

2.40e-0441192IPR000664
DomainLLGL2

STXBP5 LLGL2

2.40e-0441192IPR013577
DomainSTAT_TF_DNA-bd_sub

STAT5A STAT5B

8.28e-0471192IPR012345
DomainSTAT

STAT5A STAT5B

8.28e-0471192IPR001217
DomainSTAT_int

STAT5A STAT5B

8.28e-0471192SM00964
DomainSTAT_TF_DNA-bd

STAT5A STAT5B

8.28e-0471192IPR013801
DomainSTAT_bind

STAT5A STAT5B

8.28e-0471192PF02864
DomainSTAT_int

STAT5A STAT5B

8.28e-0471192PF02865
Domain-

STAT5A STAT5B

8.28e-04711921.10.532.10
DomainSTAT_alpha

STAT5A STAT5B

8.28e-0471192PF01017
Domain-

STAT5A STAT5B

8.28e-04711921.20.1050.20
DomainSTAT_TF_prot_interaction

STAT5A STAT5B

8.28e-0471192IPR013799
DomainSTAT_TF_coiled-coil

STAT5A STAT5B

8.28e-0471192IPR015988
Domain-

STAT5A STAT5B

8.28e-04711922.60.40.630
DomainSki_Sno

DACH2 SKOR1

8.28e-0471192PF02437
Domain-

DACH2 SKOR1

8.28e-04711923.10.260.20
DomainTransform_Ski

DACH2 SKOR1

8.28e-0471192IPR003380
DomainCadherin-like

FAT4 PCDHGA4 DAG1 CDH22 PCDH10

8.81e-041161195IPR015919
DomainSTAT_TF_alpha

STAT5A STAT5B

1.10e-0381192IPR013800
DomainDNA-bd_dom_put

DACH2 SKOR1

2.13e-03111192IPR009061
DomainLink_dom

HAPLN2 STAB1

3.00e-03131192IPR000538
DomainXlink

HAPLN2 STAB1

3.00e-03131192PF00193
DomainLINK_2

HAPLN2 STAB1

3.00e-03131192PS50963
DomainLINK

HAPLN2 STAB1

3.00e-03131192SM00445
DomainLINK_1

HAPLN2 STAB1

3.00e-03131192PS01241
DomainUBA

NACA TNRC6C BRSK1

3.33e-03471193PS50030
DomainRRM_dom

SETD1A SRSF1 SRSF7 TNRC6C SYNJ2 NONO

3.35e-032271196IPR000504
DomainRRM

SETD1A SRSF1 SRSF7 TNRC6C SYNJ2 NONO

3.57e-032301196PS50102
Domainp53-like_TF_DNA-bd

STAT5A STAT5B MGA

4.69e-03531193IPR008967
Domain-

SETD1A SRSF1 SRSF7 TNRC6C SYNJ2 NONO

4.76e-0324411963.30.70.330
DomainCadherin_CS

FAT4 PCDHGA4 CDH22 PCDH10

5.21e-031091194IPR020894
DomainIntegrin_alpha-2

ITGA10 ITGA5

5.76e-03181192IPR013649
DomainPept_M10A_stromelysin-type

MMP28 MMP20

5.76e-03181192IPR016293
DomainINTEGRIN_ALPHA

ITGA10 ITGA5

5.76e-03181192PS00242
DomainIntegrin_alpha2

ITGA10 ITGA5

5.76e-03181192PF08441
DomainIntegrin_alpha

ITGA10 ITGA5

5.76e-03181192IPR000413
DomainHA2

TDRD9 DHX37

5.76e-03181192SM00847
DomainHA2

TDRD9 DHX37

5.76e-03181192PF04408
DomainHelicase-assoc_dom

TDRD9 DHX37

5.76e-03181192IPR007502
DomainCADHERIN_1

FAT4 PCDHGA4 CDH22 PCDH10

5.92e-031131194PS00232
DomainCadherin

FAT4 PCDHGA4 CDH22 PCDH10

5.92e-031131194PF00028
DomainCADHERIN_2

FAT4 PCDHGA4 CDH22 PCDH10

6.10e-031141194PS50268
Domain-

FAT4 PCDHGA4 CDH22 PCDH10

6.10e-0311411942.60.40.60
DomainNucleotide-bd_a/b_plait

SETD1A SRSF1 SRSF7 TNRC6C SYNJ2 NONO

6.21e-032581196IPR012677
DomainCA

FAT4 PCDHGA4 CDH22 PCDH10

6.29e-031151194SM00112
PathwayREACTOME_ERYTHROPOIETIN_ACTIVATES_STAT5

STAT5A STAT5B IRS2

8.36e-067893M27907
PathwayREACTOME_SIGNALING_BY_LEPTIN

STAT5A STAT5B IRS2

3.87e-0511893M27195
PathwayREACTOME_INTERLEUKIN_7_SIGNALING

STAT5A STAT5B IRS2

1.05e-0415893MM14536
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

ACTA1 ACTA2 ACTC1 ACTG2

2.15e-0447894M39829
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

3.89e-045892M48987
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

3.89e-045892M48986
PathwayKEGG_MEDICUS_REFERENCE_PRL_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

3.89e-045892M49006
PathwayWP_ROLES_OF_CERAMIDES_IN_DEVELOPMENT_OF_INSULIN_RESISTANCE

TRAF1 PDX1 IRS2

3.93e-0423893M45533
PathwayREACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING

STAT5A STAT5B IRS2

4.47e-0424893M519
PathwayREACTOME_SIGNALING_BY_ERYTHROPOIETIN

STAT5A STAT5B IRS2

5.06e-0425893M27865
PathwayWP_EPO_RECEPTOR_SIGNALING

STAT5A STAT5B IRS2

5.69e-0426893M39687
PathwayWP_EPO_RECEPTOR_SIGNALING

STAT5A STAT5B IRS2

5.69e-0426893MM15896
PathwayREACTOME_INTERLEUKIN_9_SIGNALING

STAT5A STAT5B

5.82e-046892MM15581
PathwayREACTOME_INTERLEUKIN_21_SIGNALING

STAT5A STAT5B

5.82e-046892MM15621
Pubmed

Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.

DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

1.40e-1712129810433963
Pubmed

Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.

DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

3.64e-1713129817668377
Pubmed

The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

6.53e-178129717588759
Pubmed

DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

9.74e-1610129717984056
Pubmed

Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

1.38e-141312977739628
Pubmed

Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

1.54e-1317129711245978
Pubmed

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.

RARG ACTA1 ACTA2 ACTC1 ACTG2

1.27e-0914129521923909
Pubmed

Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-09612949971772
Pubmed

Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129410074138
Pubmed

Virus assembly and plasma membrane domains: which came first?

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129422989508
Pubmed

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-09612941540415
Pubmed

HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129411709093
Pubmed

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129410049817
Pubmed

Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129412009869
Pubmed

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129423811015
Pubmed

Retroviral assembly and budding occur through an actin-driven mechanism.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129419883584
Pubmed

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129421917091
Pubmed

HIV-1 Gag protein associates with F-actin present in microfilaments.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-09612948661406
Pubmed

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129423017337
Pubmed

Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-096129423875777
Pubmed

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.

ACTA1 ACTA2 ACTC1 ACTG2

2.69e-09612949841925
Pubmed

The cleavage of host cell proteins by HIV-1 protease.

MAP1A ACTA1 ACTA2 ACTC1 ACTG2

3.88e-091712958997639
Pubmed

The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.

ACTA1 ACTA2 ACTC1 ACTG2

6.27e-097129422535526
Pubmed

Selective targeting of ITK blocks multiple steps of HIV replication.

ACTA1 ACTA2 ACTC1 ACTG2

6.27e-097129418443296
Pubmed

The trinity of the cortical actin in the initiation of HIV-1 infection.

ACTA1 ACTA2 ACTC1 ACTG2

6.27e-097129422640593
Pubmed

The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.

PTCRA DUX4L9 DUX4L2 DUX4L4

6.27e-097129430765463
Pubmed

HIV-1 replication from after cell entry to the nuclear periphery.

ACTA1 ACTA2 ACTC1 ACTG2

6.27e-097129417504171
Pubmed

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

ACTA1 ACTA2 ACTC1 ACTG2

6.27e-097129422465675
Pubmed

Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

ACTA1 ACTA2 ACTC1 ACTG2

1.25e-088129414694110
Pubmed

Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.

ACTA1 ACTA2 ACTC1 ACTG2

1.25e-088129420147394
Pubmed

Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.

ACTA1 ACTA2 ACTC1 ACTG2

1.25e-088129423260110
Pubmed

Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.

ACTA1 ACTA2 ACTC1 ACTG2

2.24e-089129410556093
Pubmed

Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.

ACTA1 ACTA2 ACTC1 ACTG2

2.24e-08912948892894
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

ACTA1 ACTA2 ACTC1 ACTG2

2.24e-089129418775311
Pubmed

Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.

ACTA1 ACTA2 ACTC1 ACTG2

3.73e-081012941907279
Pubmed

Non-viral cellular substrates for human immunodeficiency virus type 1 protease.

ACTA1 ACTA2 ACTC1 ACTG2

3.73e-081012941991513
Pubmed

Gelsolin activity controls efficient early HIV-1 infection.

ACTA1 ACTA2 ACTC1 ACTG2

3.73e-0810129423575248
Pubmed

Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.

ACTA1 ACTA2 ACTC1

4.99e-08312937780165
Pubmed

CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.

ACTA1 ACTA2 ACTC1 ACTG2

5.84e-0811129430962377
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

ACTA1 ACTA2 ACTC1 ACTG2

5.84e-0811129423294842
Pubmed

Quantitative proteomic analysis of lentiviral vectors using 2-DE.

ACTA1 ACTA2 ACTC1 ACTG2

5.84e-0811129419639585
Pubmed

HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.

ACTA1 ACTA2 ACTC1 ACTG2

8.74e-0812129423071112
Pubmed

The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.

ACTA1 ACTA2 ACTC1 ACTG2 IRX3

1.21e-0732129523369715
Pubmed

Regulating the functions of the HIV-1 matrix protein.

ACTA1 ACTA2 ACTC1 ACTG2

1.76e-0714129417411366
Pubmed

Interaction between FGFR-2, STAT5, and progesterone receptors in breast cancer.

STAT5A STAT5B PGR

1.99e-074129321464042
Pubmed

Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.

DUX4L9 DUX4L2 DUX4L4

1.99e-074129317911620
Pubmed

The homeobox transcription factor DUXBL controls exit from totipotency.

DUX4L9 DUX4L2 DUX4L4

1.99e-074129338509386
Pubmed

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.

ACTA1 ACTA2 DAG1 ACTC1

2.39e-0715129424598388
Pubmed

Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.

ACTA1 ACTA2 ACTC1 ACTG2

4.14e-0717129417360745
Pubmed

Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.

DUX4L9 DUX4L2 DUX4L4

4.96e-075129320063414
Pubmed

Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladder.

ACTA2 SOX17 PDX1

4.96e-075129329023691
Pubmed

Alternative exon usage creates novel transcript variants of tumor suppressor SHREW-1 gene with differential tissue expression profile.

ACTA2 STAT5A STAT5B

9.89e-076129327870635
Pubmed

Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.

ACTA1 ACTA2 ACTC1 ACTG2

1.25e-0622129416526095
Pubmed

Essential and supporting host cell factors for HIV-1 budding.

ACTA1 ACTA2 ACTC1 ACTG2

1.51e-0623129422004035
Pubmed

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.

BIVM ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

1.63e-0696129623580065
Pubmed

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.

ACTA1 ACTA2 ACTC1

1.73e-06712939384381
Pubmed

A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.

ACTA1 ACTA2 ACTC1

1.73e-067129330289203
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

ACTA1 ACTA2 ACTC1 ACTG2

2.53e-0626129424742657
Pubmed

FXR1 can bind with the CFIm25/CFIm68 complex and promote the progression of urothelial carcinoma of the bladder by stabilizing TRAF1 mRNA.

TRAF1 SRSF1 SRSF7

2.75e-068129335194031
Pubmed

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation.

ACTA2 STAT5A STAT5B

2.75e-068129317187062
Pubmed

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.

ACTA1 ACTA2 ACTC1

2.75e-068129320096780
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1A MAN2A2 RARG RPS6KA2 TNRC6C ITGA5 ADGRA2 REXO1 FAM83H EPS15L1 LLGL2 MDN1 EPOP IRS2 RASAL1 AGTRAP

3.58e-0611051291635748872
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

FAT4 SRSF1 FRMPD4 ABCA13 COPRS ACTA1 ACTA2 ACTC1 ACTG2 THBS1 NONO

3.60e-065131291125798074
Pubmed

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

ACTA1 ACTA2 ACTC1

4.12e-069129312297046
Pubmed

Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.

ACTA1 ACTA2 ACTC1

5.87e-0610129321749862
Pubmed

A brain-specific homeobox gene, Bsx, is essential for proper postnatal growth and nursing.

ACTA2 STAT5A STAT5B

5.87e-0610129317485440
Pubmed

FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.

ACTA1 ACTA2 ACTC1

8.05e-0611129322207710
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

EPM2A SRSF7 ABCA13 DIDO1 ITGA5 PPP1R13L SLC13A2 CYP46A1 IRS2

8.69e-06361129926167880
Pubmed

SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.

ACTA1 ACTA2 ACTC1

1.07e-0512129331042497
Pubmed

Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.

STAT5A STAT5B

1.37e-052129223151802
Pubmed

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.

STAT5A STAT5B

1.37e-052129226999798
Pubmed

Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function.

SOX17 PGR

1.37e-052129227102016
Pubmed

Influence of TRAF1/C5 and STAT4 genes polymorphisms on susceptibility and severity of rheumatoid arthritis in Egyptian population.

TRAF1 STAT5A

1.37e-052129222196377
Pubmed

A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.

STAT5A STAT5B

1.37e-052129231443474
Pubmed

Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.

STAT5A STAT5B

1.37e-052129212377952
Pubmed

Sox17 regulates insulin secretion in the normal and pathologic mouse β cell.

SOX17 PDX1

1.37e-052129225144761
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

1.37e-052129232660355
Pubmed

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.

STAT5A STAT5B

1.37e-052129221127177
Pubmed

The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.

STAT5A STAT5B

1.37e-052129216289657
Pubmed

Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.

STAT5A STAT5B

1.37e-052129225552366
Pubmed

Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.

STAT5A STAT5B

1.37e-052129225470773
Pubmed

Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.

ACTA1 ACTC1

1.37e-052129220706863
Pubmed

Constitutively active Stat5A and Stat5B promote adipogenesis.

STAT5A STAT5B

1.37e-052129221431790
Pubmed

Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.

STAT5A STAT5B

1.37e-052129228500076
Pubmed

STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.

STAT5A STAT5B

1.37e-052129221826656
Pubmed

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

STAT5A STAT5B

1.37e-05212927720707
Pubmed

STAT5A and STAT5B have opposite correlations with drug response gene expression.

STAT5A STAT5B

1.37e-052129227264955
Pubmed

Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.

STAT5A STAT5B

1.37e-052129222159083
Pubmed

STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.

STAT5A STAT5B

1.37e-052129220008792
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

1.37e-05212921909870
Pubmed

STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.

STAT5A STAT5B

1.37e-052129233199496
Pubmed

Pdx1 restores beta cell function in Irs2 knockout mice.

PDX1 IRS2

1.37e-052129211994408
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

1.37e-052129224121496
Pubmed

A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.

ACTA1 ACTC1

1.37e-05212923023046
Pubmed

The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.

STAT5A STAT5B

1.37e-052129216502315
Pubmed

Stat5: an essential regulator of mast cell biology.

STAT5A STAT5B

1.37e-052129212217382
Pubmed

Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.

STAT5A STAT5B

1.37e-052129231599926
Pubmed

DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.

STAT5A STAT5B

1.37e-052129210594041
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

1.37e-052129224267955
Pubmed

Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.

STAT5A STAT5B

1.37e-052129221036145
InteractionPOTEE interactions

CHST14 ACTA1 ACTA2 FSTL4 ACTC1 ACTG2 POTEJ NONO

1.58e-061341228int:POTEE
InteractionACTG2 interactions

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

1.15e-05491225int:ACTG2
InteractionPOTEJ interactions

ACTA1 ACTA2 ACTC1 ACTG2 POTEJ

1.55e-05521225int:POTEJ
InteractionPFN3 interactions

ACTA2 ACTC1 POTEJ

2.52e-05101223int:PFN3
CytobandEnsembl 112 genes in cytogenetic band chr4q35

DUX4L9 DUX4L2 DUX4 STOX2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

5.64e-111171309chr4q35
Cytoband4q35.2

DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

1.29e-102713064q35.2
Cytoband17q11.2

COPRS STAT5A STAT5B RAB11FIP4

2.81e-04110130417q11.2
Cytoband4q13

UGT2B15 UGT2B17

8.16e-041513024q13
Cytoband16q24

APRT ZNF469

1.05e-0317130216q24
GeneFamilyPRD class homeoboxes and pseudogenes

UNCX DUX4L9 TPRX2 DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

6.98e-1092899521
GeneFamilyActins

ACTA1 ACTA2 ACTC1 ACTG2

8.17e-096894929
GeneFamilyRNA binding motif containing|Serine and arginine rich splicing factors

SRSF1 SRSF7

1.53e-0312892737
CoexpressionDESCARTES_FETAL_STOMACH_STROMAL_CELLS

ACTA2 ACTG2 TMEM119 EMILIN1 PLAC9

4.56e-06501285M40304
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_1000

TRAF1 AMN UNCX CYP4A11 MFSD6L CBARP IRX3 ALDH1L1 SLC13A2 C2orf72 CDH22 MYO15B LLGL2 UGT2B15 UGT2B17 AGTRAP

7.93e-0678411916gudmap_developingKidney_e15.5_early proxim tubul_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_100

ACTA1 ACTA2 ACTC1 ACTG2

1.27e-05261194gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#1_top-relative-expression-ranked_1000

ACTA1 ACTA2 ACTC1 ACTG2 ADGRA2 STOX2

1.31e-05921196gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k1
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#1_top-relative-expression-ranked_500

TRAF1 AMN UNCX CYP4A11 ALDH1L1 MYO15B

1.58e-05951196gudmap_developingKidney_e15.5_early proxim tubul_500_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#3_top-relative-expression-ranked_100

ACTA1 ACTA2 ACTC1 ACTG2

1.73e-05281194gudmap_developingLowerUrinaryTract_P1_bladder_B_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#4_top-relative-expression-ranked_200

ACTA1 ACTA2 ACTG2 PLAC9

2.62e-05311194gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_200_k4
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#3_top-relative-expression-ranked_1000

TRAF1 UNCX CYP4A11 CBARP IRX3 CDH22 AGTRAP

3.34e-051601197gudmap_developingKidney_e15.5_early proxim tubul_1000_k3
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3

VEGFC ZCCHC24 FAT4 UNCX MAP1A ACTG2 TMEM119 CBARP F2RL2 ADGRA2 DNAH7 EMILIN1 C2orf72 HOXB2 ZNF469 DACH2 FMN2 PCDH10

3.78e-05109411918ratio_EB_vs_SC_2500_K3
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000

VEGFC FAT4 UNCX MMP28 ACTA2 SOX17 ACTG2 TMEM119 IRX3 F2RL2 ADGRA2 DNAH7 EMILIN1 C2orf72 HOXB2 DACH2 PCDH10

3.93e-0599411917PCBC_ratio_EB_vs_SC_1000
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#5_top-relative-expression-ranked_200

AMN CYP4A11 ALDH1L1 UGT2B15

7.33e-05401194gudmap_developingKidney_e15.5_early proxim tubul_200_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#3_top-relative-expression-ranked_100

ACTA2 ACTC1 ACTG2

7.43e-05151193gudmap_developingLowerUrinaryTract_P1_ureter_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500

FAT4 ACTA1 ACTA2 ACTC1 ACTG2 TNRC6C STAT5A DACH2 FMN2 PCDH10

9.96e-0540711910gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_CardiacMyocyte_top-relative-expression-ranked_1000

VEGFC ZCCHC24 MAP1A PCDHGA4 RPS6KA2 ACTA2 ITGA10 DGKG TMEM119 F2RL2 EMILIN1 THBS1 ZNF469 SYNJ2 FMN2 PLAC9

1.10e-0497511916PCBC_ctl_CardiacMyocyte_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#5_top-relative-expression-ranked_200

ACTA1 ACTC1 ACTG2

1.10e-04171193gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_200_k5
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#3_top-relative-expression-ranked_100

ACTC1 ACTG2 DACH2

1.32e-04181193gudmap_developingKidney_e15.5_Podocyte cells_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_500

ACTA1 ACTA2 ACTC1 ACTG2

1.51e-04481194gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_100

ACTA1 ACTA2 ACTG2

1.56e-04191193gudmap_developingLowerUrinaryTract_adult_bladder_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

FAT4 DHX37 ACTA1 ACTA2 ACTC1 ACTG2 TNRC6C ADGRA2 STAT5A STAT5B STOX2 DACH2 FMN2 PCDH10

1.70e-0480611914gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_200

ACTA1 ACTA2 ACTC1 ACTG2

1.77e-04501194gudmap_developingLowerUrinaryTract_P1_bladder_B_200_k2
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#3_top-relative-expression-ranked_100

AMN CYP4A11 UGT2B15

3.61e-04251193gudmap_developingKidney_e14.5 whole kidney - wildtype_100_k3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1A ACTA1 ACTA2 HAPLN2 ACTC1 ACTG2 EMILIN1 EPOP PLAC9

1.35e-091731239ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1A ACTA1 ACTA2 HAPLN2 ACTC1 ACTG2 EMILIN1 EPOP PLAC9

1.35e-091731239b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZCCHC24 FRMPD4 MAP1A TDRD9 ACTA2 ACTC1 ACTG2 ITGA5 EMILIN1

2.93e-09189123963449d9f1e78ff2bc8786eb88a0d177fe30c7f4d
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TDRD9 ACTA2 ACTC1 ACTG2 DGKG TRDN PGR THBS1 PLAC9

4.60e-0919912398ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

ZCCHC24 ACTA2 ACTG2 ITGA5 ADGRA2 EMILIN1 THBS1 ZNF469

3.58e-081781238142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

MAP1A ACTA1 ACTA2 ACTC1 ACTG2 EMILIN1 PGR PLAC9

4.44e-081831238d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA1 ACTA2 HAPLN2 ACTC1 ACTG2 DGKG EMILIN1 PLAC9

7.54e-081961238ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA1 ACTA2 HAPLN2 ACTC1 ACTG2 DGKG EMILIN1 PLAC9

7.54e-08196123870b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

ACTA2 ITGA5 ADGRA2 EMILIN1 STAB1 THBS1 ZNF469

4.41e-071681237aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC FAT4 SOX17 DAG1 BCDIN3D STOX2 PLAC9

4.77e-07170123750c6c571591aa4b218caefe5778c570c809f567e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC FAT4 SOX17 DAG1 BCDIN3D STOX2 PLAC9

4.77e-0717012378fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC FAT4 SOX17 DAG1 BCDIN3D STOX2 PLAC9

4.77e-0717012373232db50b1a40f861e981a1b9c9073b81af9f832
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VEGFC FAT4 MMP28 RPS6KA2 SOX17 ITGA5 SYNJ2

6.51e-0717812375f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCellCOPD-Stromal-SMC|World / Disease state, Lineage and Cell class

ACTA2 HAPLN2 ACTC1 ACTG2 DGKG PGR PLAC9

6.76e-071791237b2709537ec1b46457ab85261f4cdd354e60a8b29
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A ACTA2 ACTC1 ACTG2 HOXB2 THBS1 BRSK1

7.01e-071801237d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FRMPD4 MMP28 SOX17 F2RL2 STAB1 SCARF1 SYNJ2

7.01e-0718012375861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A ACTA2 ACTC1 ACTG2 HOXB2 THBS1 BRSK1

7.01e-071801237573308d43425d9fba20787abdb7f8efefc48efb5
ToppCellPericytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MAP1A ACTA2 ACTG2 DGKG ADGRA2 EMILIN1 PLAC9

7.84e-0718312374617b18da8d699a44e4c47980197b1e7eb951470
ToppCellPericytes-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ACTA2 ACTC1 ACTG2 DGKG ADGRA2 EMILIN1 PLAC9

9.06e-07187123735f25780d113f60bf4c13749013c09612ee4ff41
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZCCHC24 FRMPD4 ACTA2 ACTC1 ACTG2 ITGA5 EMILIN1

9.72e-071891237f7e2ee5047792ab9ef6472fa88e2d193cdea6fa0
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VEGFC MMP28 SOX17 ITGA5 TRDN SYNJ2 PCDH10

1.01e-061901237aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

ACTA2 ACTC1 DGKG ITGA5 ADGRA2 EMILIN1 THBS1

1.04e-061911237fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ZCCHC24 MAP1A ACTA1 ACTC1 TMEM119 EMILIN1 ZNF469

1.16e-06194123755b97095a7a17a312c616703d291738a0f806339
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ITGA10 ACTG2 ADGRA2 EMILIN1 ALG9 PLAC9

1.24e-06196123740e6900a0d56088a40d37ec312f53207ea952602
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ITGA10 ACTG2 ADGRA2 EMILIN1 ALG9 PLAC9

1.24e-0619612377acd782a587b7d331517f60daa8b5c2177bedfc7
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA2 HAPLN2 ACTC1 ACTG2 DGKG EMILIN1 PLAC9

1.24e-061961237208ddedd29e1b9ca89cbb9b527c2e193a44cada2
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ITGA10 ACTG2 ADGRA2 EMILIN1 ALG9 PLAC9

1.24e-0619612370b247cf981981ae61aca5de82ef687e8d783c9ef
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ITGA10 ACTG2 F2RL2 ADGRA2 EMILIN1 PLAC9

1.28e-061971237983502a99e6d59bb36225b0246a9990604de1a01
ToppCellFibroblast|World / shred by cell class for bronchial biopsy

ACTA2 ACTC1 ACTG2 ADGRA2 EMILIN1 THBS1 PLAC9

1.28e-0619712378bf9846228b6b6721b10375fe54a2fb389ff64a6
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 MAP1A TMEM119 ADGRA2 EMILIN1 ZNF469 PLAC9

1.37e-06199123721335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA2 HAPLN2 ACTG2 DGKG ADGRA2 C2orf72 PLAC9

1.42e-06200123712326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ZCCHC24 ACTA2 TMEM119 F2RL2 ADGRA2 EMILIN1 PLAC9

1.42e-0620012374f7e26b27bd51c32420ed8c2f52d070aee542159
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

VEGFC FAT4 MMP28 RPS6KA2 TRDN SYNJ2 PCDH10

1.42e-062001237ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Cerebellum / BrainAtlas - Mouse McCarroll V32

ACTA2 ITGA10 ACTG2 ZBP1 ZNF469 LLGL2

1.99e-0613412368a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)|Cerebellum / BrainAtlas - Mouse McCarroll V32

ACTA2 ITGA10 ACTG2 ZBP1 ZNF469 LLGL2

1.99e-0613412361fa13185a4dfb4563473184c0c4f449011d88631
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

ACTA2 ITGA10 ACTG2 ZBP1 ZNF469 LLGL2

1.99e-0613412361ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

FRMPD4 FIGNL2 GRIN2B SKOR1 ACP4 EIF4G3

3.68e-0614912366e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACTA2 ITGA10 HAPLN2 ACTG2 DGKG BRSK1

6.17e-0616312368f24cef152f5965727bbeee116bd26c75cbba82a
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 ACTA2 ACTG2 EMILIN1 DACH2 PCDH10

6.39e-061641236e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

FRMPD4 FSTL4 PGR FAM83H SKOR1 EIF4G3

7.09e-0616712369efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AMN ACTA2 ITGA10 ACTC1 ACTG2 TRDN

7.09e-06167123691b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

FRMPD4 FSTL4 PGR FAM83H SKOR1 EIF4G3

7.09e-061671236904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

ACTA2 ITGA10 ACTG2 DGKG CBARP BRSK1

7.09e-061671236c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO6 ACTA2 HAPLN2 ACTC1 ACTG2 EMILIN1

8.68e-0617312363001dd39244ef0a5a475d569a78f4ae427a55db6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO6 ACTA2 HAPLN2 ACTC1 ACTG2 EMILIN1

8.68e-061731236c88883fb2a33e21d4201aa393674aa3f2ad780c9
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ACTA2 ACTC1 ACTG2 EMILIN1 PGR PLAC9

9.27e-061751236fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 ACTA2 ITGA10 ACTG2 DACH2 PCDH10

9.89e-061771236b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACTA2 ACTC1 ACTG2 F2RL2 EMILIN1 PLAC9

1.02e-051781236c661246269ce26c4fc62e12f86c5f90a2dcfdce0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACTA2 ACTC1 ACTG2 F2RL2 EMILIN1 PLAC9

1.02e-051781236e5e5f5b4a27e120a1076b1cb250fa25d0c336956
ToppCellControl-Stromal-SMC|Control / Disease state, Lineage and Cell class

ACTA2 HAPLN2 ACTC1 ACTG2 EMILIN1 PLAC9

1.05e-0517912361378051bc62009eec2dbecf3d5d89baedbeb84eb
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ACTA2 ACTG2 DGKG EMILIN1 HOXB2 PLAC9

1.09e-0518012367085a851807e6a833965e1366946db0bbc5174e2
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A ACTA2 PPP1R13L STAB1 SCARF1 MAJIN

1.09e-05180123679c5725f02e038d0187f4a1e1591f2492538aa57
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTA2 ACTC1 ACTG2 DGKG GRIN2B TRDN

1.19e-0518312366f5dbac2748f50105f0f548d189c42ef14287019
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRMPD4 ABCA13 GRIN2B TRDN PCDH10

1.23e-0518412362cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRMPD4 ABCA13 GRIN2B TRDN PCDH10

1.23e-051841236ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRMPD4 ABCA13 GRIN2B TRDN PCDH10

1.23e-0518412362b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellControl-Stromal-SMC|World / Disease state, Lineage and Cell class

ACTA2 HAPLN2 ACTC1 ACTG2 EMILIN1 PLAC9

1.23e-05184123688b1a4c9a96a99fc3a39f7a2c3d0838739606f3e
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4|TCGA-Bladder / Sample_Type by Project: Shred V9

ZCCHC24 ACTA2 ACTG2 TMEM119 ADGRA2 EMILIN1

1.27e-051851236e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACTA2 HAPLN2 ACTC1 ACTG2 DGKG PLAC9

1.31e-051861236c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IRF2BP2 GRIN2B STAB1 THBS1 DACH2 IRS2

1.31e-05186123623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VEGFC FRMPD4 MMP28 GRIN2B STOX2 PCDH10

1.31e-05186123692092f11ecce22c14f244e42c499af0822977e6f
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FRMPD4 MMP28 SOX17 F2RL2 STAB1 SCARF1

1.35e-05187123603de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC ACTA2 SOX17 PGR PLAC9 BRSK1

1.39e-051881236ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACTA2 HAPLN2 DGKG ADGRA2 DACH2 PLAC9

1.43e-051891236fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VEGFC SOX17 ITGA5 TRDN SYNJ2 PCDH10

1.43e-051891236b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 IRX3 DNAH7 THBS1 STOX2 RASAL1

1.43e-051891236bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 ACTA2 ACTG2 TMEM119 EMILIN1 PLAC9

1.48e-051901236c01a8bfb9fbc0e6f37d7e9be25512eda63acabbc
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MMP28 RPS6KA2 SOX17 STAB1 SCARF1 SYNJ2

1.52e-051911236e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VEGFC MMP28 RPS6KA2 SOX17 ITGA5 SYNJ2

1.57e-051921236bacbaef1f230051335f4433e55db07a161b96b4c
ToppCellFibroblast-D_(Pericyte)|World / shred on cell class and cell subclass (v4)

ACTA2 ITGA10 ACTC1 ACTG2 HOXB2 PLAC9

1.57e-0519212368c13c351fcc3d88e8c2ffa017e71ff6272cc6fac
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP1A ACTA2 ACTC1 ACTG2 TRDN PLAC9

1.57e-0519212362cc712186e37fb21a964c032765c36a8b4a852cf
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 ADGRA2 STAB1 SCARF1 THBS1 PLAC9

1.57e-051921236a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ZCCHC24 RARG ACTG2 TMEM119 TRDN PLAC9

1.62e-051931236e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ZCCHC24 RARG ACTG2 TMEM119 TRDN PLAC9

1.62e-051931236b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VEGFC ZCCHC24 MAP1A SYNJ2 RAB11FIP4 PCDH10

1.62e-051931236947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VEGFC MMP28 RPS6KA2 SOX17 ITGA5 SYNJ2

1.62e-0519312366a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VEGFC MMP28 GRIN2B ITGA5 STAB1 DACH2

1.62e-0519312367261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|metastatic_Brain / Location, Cell class and cell subclass

MAP1A ACTA2 ACTG2 ADGRA2 EMILIN1 PLAC9

1.66e-051941236d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VEGFC MMP28 SOX17 IER3 SYNJ2 PLAC9

1.66e-051941236582db7f7fa9aa08027ae18ed607945b5d1dc908a
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ACTG2 F2RL2 ADGRA2 EMILIN1 PLAC9

1.66e-051941236a7731378f44ca1a229311686caf5740c742d21ba
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACTA2 HAPLN2 ACTC1 ADGRA2 EMILIN1 PLAC9

1.66e-0519412365099e6ad7c19e5f8b73449d904aaefd97f1b1959
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACTA2 HAPLN2 ACTC1 ADGRA2 EMILIN1 PLAC9

1.66e-05194123671734ef7b34ab33b349595368176fa0e1175d4d0
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VEGFC MMP28 SOX17 IER3 SYNJ2 PLAC9

1.66e-051941236bda89111386398a072b70e8153b2a762298a047a
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARG SOX17 EMILIN1 STAB1 SCARF1 STOX2

1.71e-051951236f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARG SOX17 EMILIN1 STAB1 SCARF1 STOX2

1.71e-051951236ea1b00805391dca8be0883b635768b296369919a
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARG SOX17 EMILIN1 STAB1 SCARF1 STOX2

1.71e-05195123685df110f753f58ab017018c54ee454edb4428e29
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

TMEM119 F2RL2 ADGRA2 EMILIN1 PGR PLAC9

1.71e-0519512365870b2956d50d6550a3174a220a6cc70c5538d70
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA2 HAPLN2 ACTG2 DGKG EMILIN1 PLAC9

1.76e-051961236cda3681f032f740cb09c64c62b9153cb62dbb5d2
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ACTG2 F2RL2 ADGRA2 ALG9 PLAC9

1.76e-0519612369a420a4eb46cb554bec641726fea5398ff60f630
ToppCellBronchial_Biopsy-Mesenchymal|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

TMEM119 F2RL2 ADGRA2 EMILIN1 PGR PLAC9

1.76e-051961236d37d821229dce716a05c2a5865415e10f79032de
ToppCell(5)_Fibroblast-K_(Pericytes)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ACTA1 ACTA2 ACTC1 ACTG2 DGKG PLAC9

1.76e-051961236e3c89c5bd674289738d5590ebfd30c605f5156a5
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA2 HAPLN2 ACTG2 DGKG TMEM119 PLAC9

1.76e-051961236f78951b460913866d092ba92af70ea76a2afa73e
ToppCell15-Distal-Mesenchymal|Distal / Age, Tissue, Lineage and Cell class

ACTA2 ACTG2 TMEM119 EMILIN1 HOXB2 PLAC9

1.76e-051961236b8d95b5f4780e73d16dcc528e70a5496f0314373
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ACTG2 F2RL2 ADGRA2 ALG9 PLAC9

1.76e-051961236cb5860f580b477bfa52b22cdc21b808e1371e6e0
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA2 HAPLN2 ACTG2 DGKG EMILIN1 PLAC9

1.76e-051961236b55aa507429ddce89ad4f42ab6daeca2f34fd676
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA2 HAPLN2 ACTG2 DGKG TMEM119 PLAC9

1.76e-05196123669ad90a429af4dad5a45556544224001ebcb1607
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACTA2 HAPLN2 ACTG2 DGKG TMEM119 PLAC9

1.76e-0519612364da96672a9c72268cfcc82d61eb3caae6e02d4c4
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ITGA10 ADGRA2 EMILIN1 ALG9 PLAC9

1.76e-05196123673f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACTA2 ACTG2 DGKG ITGA5 ADGRA2 PGR

1.81e-051971236bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACTA2 ACTG2 F2RL2 ADGRA2 ALG9 PLAC9

1.81e-05197123612370ee857fddf1cf26196b23c21b68dcea48eb3
ComputationalMuscle genes.

ACTA1 ACTA2 ACTC1 ACTG2

1.03e-0437724MODULE_512
ComputationalGenes in the cancer module 387.

ACTA1 ACTA2 ACTC1 ACTG2

3.12e-0449724MODULE_387
ComputationalGenes in the cancer module 329.

ACTA1 ACTA2 ACTC1 ACTG2

3.65e-0451724MODULE_329
DrugNsc687160

ACTA1 ACTA2 ACTC1 ACTG2

2.74e-06181284CID005459290
Drugtolytoxin

ACTA1 ACTA2 ACTC1 ACTG2

3.46e-06191284CID006440827
Drugm2-19

ACTA1 ACTA2 ACTC1 ACTG2

3.46e-06191284CID000079129
DrugNSC312786

ACTA1 ACTA2 ACTC1 ACTG2

5.30e-06211284CID000329495
DrugAC1L8NVR

ACTA1 ACTA2 ACTC1 ACTG2

5.30e-06211284CID000384633
Druglosartan

CYP4A11 MMP28 ACTA1 ACTA2 ITGA10 ACTC1 ACTG2 ITGA5 MMP20 THBS1 AGTRAP

9.81e-0637812811CID000003961
DrugCID5288653

ACTA1 ACTA2 ACTC1 ACTG2

1.76e-05281284CID005288653
Drugsulphoxide

ACTA1 ACTA2 ACTC1 ACTG2 GRIN2B KYAT1

2.30e-051011286CID000008442
Drugazaspiracid

ACTA1 ACTA2 ACTC1 ACTG2

2.33e-05301284CID006451158
DrugAC1L1HS4

ACTA1 ACTA2 ACTC1 ACTG2

3.03e-05321284CID000004267
DrugN,N'-p-phenylenedimaleimide

ACTA1 ACTA2 ACTC1 ACTG2

3.88e-05341284CID000076765
Drug1,N6-ethenoadenosine 5'-diphosphate

ACTA1 ACTA2 ACTC1 ACTG2

3.88e-05341284CID000001312
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTA1 ACTA2 ACTC1 ACTG2

1.86e-0881214DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTA1 ACTA2 ACTC1 ACTG2

1.86e-0881214DOID:0081112 (implicated_via_orthology)
DiseaseMoyamoya disease (implicated_via_orthology)

ACTA1 ACTA2 ACTC1 ACTG2

1.86e-0881214DOID:13099 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTA1 ACTA2 ACTC1 ACTG2

1.86e-0881214DOID:14004 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTA1 ACTA2 ACTC1 ACTG2

5.54e-08101214DOID:10486 (implicated_via_orthology)
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTA1 ACTA2 ACTC1 ACTG2

5.54e-08101214DOID:13832 (implicated_via_orthology)
DiseaseAmelogenesis imperfecta

MMP20 FAM83H ACP4

4.39e-05171213cv:C0002452
DiseaseJoint laxity

CHST14 ZNF469

4.99e-0531212C0086437
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

4.99e-0531212EFO_0800574
DiseaseJoint Instability

CHST14 ZNF469

4.99e-0531212C0022410
DiseaseX-25937 measurement

UGT2B15 UGT2B17

9.95e-0541212EFO_0800937
DiseaseMammary Carcinoma, Human

VEGFC RCCD1 ACTA2 APRT STAT5A PGR THBS1 LLGL2 SYNJ2

3.24e-045251219C4704874
DiseaseMammary Neoplasms, Human

VEGFC RCCD1 ACTA2 APRT STAT5A PGR THBS1 LLGL2 SYNJ2

3.24e-045251219C1257931
DiseaseMammary Neoplasms

VEGFC RCCD1 ACTA2 APRT STAT5A PGR THBS1 LLGL2 SYNJ2

3.33e-045271219C1458155
Diseaseandrosterone sulfate measurement

TPRX2 UGT2B15 UGT2B17

3.35e-04331213EFO_0021117
DiseaseX-24574 measurement

UGT2B15 UGT2B17

3.46e-0471212EFO_0800897
Disease21-hydroxypregnenolone disulfate measurement

CYP4A11 TPRX2

3.46e-0471212EFO_0800281
DiseaseBreast Carcinoma

VEGFC RCCD1 ACTA2 APRT STAT5A PGR THBS1 LLGL2 SYNJ2

3.87e-045381219C0678222
Diseaseaortic dissection (is_marker_for)

ACTA1 NONO

4.59e-0481212DOID:0080685 (is_marker_for)
Diseaseplacental insufficiency (biomarker_via_orthology)

PDX1 GRIN2B

4.59e-0481212DOID:3891 (biomarker_via_orthology)
Diseasedeoxycholic acid glucuronide measurement

UGT2B15 UGT2B17

4.59e-0481212EFO_0800575
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

7.35e-04101212EFO_0022090
DiseaseDNA repair protein RAD51 homolog 4 measurement

UGT2B15 UGT2B17

8.95e-04111212EFO_0801531
DiseaseCystic Kidney Diseases

FAT4 ALG9

8.95e-04111212C1691228
DiseasePrecursor B-Cell Lymphoblastic Leukemia-Lymphoma

DUX4 MGA

1.07e-03121212C0023485
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

UGT2B15 UGT2B17

1.07e-03121212EFO_0800291
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

UGT2B15 UGT2B17

1.26e-03131212EFO_0800293
DiseaseX-19141 measurement

UGT2B15 UGT2B17

1.26e-03131212EFO_0800799
DiseaseCarcinoma, Granular Cell

FAT4 STAT5A PGR UGT2B17

1.35e-031161214C0205644
DiseaseAdenocarcinoma, Tubular

FAT4 STAT5A PGR UGT2B17

1.35e-031161214C0205645
DiseaseAdenocarcinoma, Oxyphilic

FAT4 STAT5A PGR UGT2B17

1.35e-031161214C0205642
DiseaseCarcinoma, Cribriform

FAT4 STAT5A PGR UGT2B17

1.35e-031161214C0205643
DiseaseAdenocarcinoma, Basal Cell

FAT4 STAT5A PGR UGT2B17

1.35e-031161214C0205641
DiseaseAdenocarcinoma

FAT4 STAT5A PGR UGT2B17

1.35e-031161214C0001418
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

UGT2B15 UGT2B17

1.47e-03141212EFO_0800283
DiseaseMalignant neoplasm of breast

VEGFC SRSF1 RARG RCCD1 ACTA2 DGKG APRT STAT5A PGR THBS1 LLGL2 SYNJ2

1.56e-03107412112C0006142
DiseaseT-Cell Lymphoma

STAT5B MGA

1.93e-03161212C0079772
Diseasemetabolite measurement

SETD1A FOXO6 CYP4A11 ALDH1L1 KYAT1 STAB1 UGT2B15 UGT2B17

2.21e-035601218EFO_0004725
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

UGT2B15 UGT2B17

2.44e-03181212EFO_0800288
Diseasekeratoconus

GRIN2B ZNF469 RAB11FIP4

2.55e-03661213MONDO_0015486
Diseaseetiocholanolone glucuronide measurement

UGT2B15 UGT2B17

2.72e-03191212EFO_0800362
Diseaseandrosterone glucuronide measurement

UGT2B15 UGT2B17

3.02e-03201212EFO_0800317
Diseasewellbeing measurement, alcohol consumption measurement

STXBP5 MMP20 PCDH10

3.53e-03741213EFO_0007869, EFO_0007878
DiseaseSplenomegaly

STAT5B EIF2AK1

3.65e-03221212C0038002
DiseaseX-24947 measurement

UGT2B15 UGT2B17

3.65e-03221212EFO_0800910
Diseaseprogression free survival, ovarian serous carcinoma

ABCA13 MGA

3.65e-03221212EFO_0004920, EFO_1001516

Protein segments in the cluster

PeptideGeneStartEntry
ARAGDAVAFPHPRPF

CBARP

361

Q8N350
DPFGGDPFKESDPFR

EPS15L1

656

Q9UBC2
DFPEAPDPFQPLGAD

EPS15L1

806

Q9UBC2
PFAGPLAARPRAADG

EPM2A

286

B3EWF7
AFPGRAFPPGADGAE

CCDC117

26

Q8IWD4
DFARAVFPPEPGAAK

C2orf72

51

A6NCS6
FSPGPAFPFVKALEA

NT5C1A

91

Q9BXI3
AGFAGDDAPRAVFPS

ACTA1

21

P68133
PRALPAAAEDGSPVF

ADGRA2

1096

Q96PE1
RGDFAYAAPAPPDGA

DUX4L4

236

P0CJ87
SRVLAPGAAPFGNFP

BCDIN3D

21

Q7Z5W3
PSEFRGQLPKPFAEG

ALG9

491

Q9H6U8
RDFNDNPPSFPPGDI

FAT4

1411

Q6V0I7
AGFAGDDAPRAVFPS

ACTA2

21

P62736
PNPEVFDPFRFAPGS

CYP4A11

426

Q02928
PNGRFSEKEVFLPPG

ABCA13

506

Q86UQ4
PPFEDIRFGPFTGNT

BIVM

251

Q86UB2
GFAGDDAPRAVFPSI

ACTG2

21

P63267
AAAPAGAPLGFRNPV

AMN

396

Q9BXJ7
RGDFAYAAPAPPDGA

DUX4L6

236

P0CJ89
QALPAGFPGPFIFAD

DACH2

436

Q96NX9
FPDFPTPGVVFRDIS

APRT

16

P07741
DEAGVPARALFPPSA

RASAL1

551

O95294
AEDGAPAPFIAVQPF

RCCD1

276

A6NED2
NSVSDFPPPAGREFI

RAB3GAP1

926

Q15042
PFAFPGALRGSPPFE

RARG

26

P13631
FADGELIPREPGFFP

RAB11FIP4

121

Q86YS3
NENPGARFPLPEAFD

PCDHGA4

176

Q9Y5G9
ARFPLPEAFDPDVGV

PCDHGA4

181

Q9Y5G9
PAPGFRAFFSAPPSA

PATL1

311

Q86TB9
AFFAGDLPPPLQAGA

PTCRA

266

Q6ISU1
EQPDFLPRPTDGAAS

MDN1

3996

Q9NU22
PPAFNRAAPGAEFAP

NONO

451

Q15233
FTFDPLPEPAAAPAG

IER3

36

P46695
PARPSLDFPASAFGF

MAP1A

2156

P78559
PPPKERAATGFFGFL

MAJIN

146

Q3KP22
RGDFAYAAPAPPDGA

DUX4

236

Q9UBX2
ARSGPVRFEPGFQPF

LLGL2

566

Q6P1M3
DPGVRSFGFPRPQQA

HAPLN2

316

Q9GZV7
TGTNPASPDAGFPFV

MGA

766

Q8IWI9
GKPRPAFSNALEPDF

DAG1

686

Q14118
RGDFAYAAPAPPDGA

DUX4L3

236

P0CJ86
PGFRNPPGESDRETF

MFSD6L

151

Q8IWD5
DPCAFQRGPAPEFSA

PDX1

16

P52945
AAAGPLGAAPDRFPA

FOXO6

421

A8MYZ6
RGAPPSPEAGFATAD

COPRS

26

Q9NQ92
AVAFPFAPPAAAAEP

MICB

11

Q29980
AFIQEAAAFAGPPDP

TEPSIN

96

Q96N21
PPNPTAVAADFDNRG

PTPDC1

346

A2A3K4
TPGTRFPLESAFDPD

PCDH10

136

Q9P2E7
FARPDVTTEPFGPDN

ARHGAP32

1476

A7KAX9
RGAPPNSFEEFPFSA

F2RL2

41

O00254
PEDVFSGRQDSPFLP

HOXB2

291

P14652
DFGAPKVGVAAPPFL

PYGO2

81

Q9BRQ0
GLFPADIVQPAAAPD

MYO15B

1471

Q96JP2
VAGANPAAFPDFPLG

PGR

406

P06401
AGLFPEAAPGSPEAR

ACP4

121

Q9BZG2
PPRVGGFNLDAEAPA

ITGA5

36

P08648
AEAPAVLSGPPGSFF

ITGA5

46

P08648
GRAAAGDAPPAAAPA

IRS2

146

Q9Y4H2
NIDFGEPGARLSPPA

IRS2

921

Q9Y4H2
GPTPGLNFFRDTPDF

DGKG

471

P49619
SVPGAGAPFRPLFND

CDK2AP2

36

O75956
GAPFRPLFNDFGPPS

CDK2AP2

41

O75956
EDPLTFNPDRFGPGA

CYP46A1

406

Q9Y6A2
DGAGAVAAPPAIDFP

EIF2AK1

16

Q9BQI3
SPAPAAPGDLRQEHF

EPOP

231

A6NHQ4
AIAAPPPGFRDSSDE

FRMPD4

806

Q14CM0
RGDFAYAAPAPPDGA

DUX4L9

236

Q6RFH8
IRTPFAGVDDFFIPP

FSTL4

586

Q6MZW2
GRAFIEPPPFDLAKA

DNAH7

3406

Q8WXX0
FPEENIASNDGPRGP

DIDO1

1781

Q9BTC0
RGDFAYAAPAPPDGA

DUX4L7

236

P0CJ90
PVFSFSPEPGAGDEA

BRSK1

451

Q8TDC3
ARPPGFPVLSGDFFS

MAN2A2

481

P49641
PEPPQDARFGFAMGA

ITGA10

541

O75578
GPPSPEPDFSVFRDF

CDH22

736

Q9UJ99
EGAPAAPVPQVAFSA

EMILIN1

861

Q9Y6C2
EKFPERAPAPRGGFA

FIGNL2

346

A6NMB9
RGDFAYAAPAPPDGA

DUX4L5

236

P0CJ88
PDDFTLGAGPRFPEL

FAM83H

486

Q6ZRV2
TAFPFPEAGPGEEAA

FMN2

321

Q9NZ56
SAVFGDFEQFPPPEI

DHX37

686

Q8IY37
PVATPPNAIVFSFGD

SLC13A2

516

Q13183
GSPLAEGPQAFFPER

PPP1R13L

186

Q8WUF5
FPEGRSPPGAAASAA

IRF2BP2

66

Q7Z5L9
LPRGPDFTPAFADFG

EIF4G3

671

O43432
AAAAAFARPAEPEGG

IRX3

446

P78415
PFDGPRGTLAHAFAP

MMP20

181

O60882
AGGLPRHPDAALFFP

MMP28

411

Q9H239
PTVGPDEDAFPLAFD

REXO1

136

Q8N1G1
PPAGRPAFGDLAAED

SKOR1

726

P84550
PLDGVDPDPAFFAAP

SOX17

226

Q9H6I2
PPVAFGRAGAPVAAS

TNRC6C

851

Q9HCJ0
PPAAGTVFPQGDFLS

SYNJ2

1371

O15056
LGAPPAFPAGAAREE

TDRD9

26

Q8NDG6
GFPDFPPPDFAVEAF

KYAT1

36

Q16773
KAGFAGDDAPRAVFP

POTEJ

681

P0CG39
FEIPTFPPGAQADDG

RNF126

91

Q9BV68
FPPGAQADDGRDPES

RNF126

96

Q9BV68
DVFLAFAQGPSPPRG

SMIM40

11

Q5STR5
NAFAEPGRVPFAVPD

STAT5B

486

P51692
PVETPEAPNRGFFKG

STXBP5

1036

Q5T5C0
EPPGAPFAENTAERF

SETD1A

391

O15047
FGEAFLPFPPPQEAA

SETD1A

711

O15047
AGAFPPPEDASTPFA

SCARF1

561

Q14162
NAFAEPGRVPFAVPD

STAT5A

486

P42229
AGFAGDDAPRAVFPS

ACTC1

21

P68032
GNQVPRPGFFFEPTV

ALDH1L1

776

O75891
PSPAGDDVTFPEFLR

CHST14

251

Q8NCH0
APADPFAVPEGRSQD

AGTRAP

141

Q6RW13
DPAAGAAPFRFVARP

ZNF511

26

Q8NB15
GPDPSSPAFRIEDAN

THBS1

51

P07996
GPREAPAAAAAFESG

VEGFC

21

P49767
AAGPEASFEARIPSP

ZBP1

296

Q9H171
AAAEPFSPPRGDSAQ

PLAC9

21

Q5JTB6
GAGPAFNFRASAEPP

STOX2

891

Q9P2F5
NPAFGFVSSEPGDPE

SOGA1

956

O94964
PPGFAFVEFEDPRDA

SRSF7

46

Q16629
FEASNPPFDVGRPFD

TMEM131

1156

Q92545
SAPAEAGFRAPPAIN

TCTN1

561

Q2MV58
GSSPRPAPDENEFPF

TRAF1

6

Q13077
DGPGPFTVFAPSNEA

STAB1

536

Q9NY15
GSPRGVSFQFPFPAL

ZNF469

266

Q96JG9
GFQFPFTPADRPGES

TRDN

701

Q13061
RGGPPFAFVEFEDPR

SRSF1

51

Q07955
EFPRPFLPNVDFVGG

UGT2B15

266

P54855
GPSPPTNFLDGIVDF

TMEM119

76

Q4V9L6
IPFDSLGRDAPFSEP

WWC3

416

Q9ULE0
EFPRPFLPNVDFVGG

UGT2B17

266

O75795
LVPVAAASFPGGPEF

TPRX2

101

P0DV77
PGGAPDSAFARRSPD

UNCX

431

A6NJT0
AFDAFRPEPTAGAAP

ZCCHC24

36

Q8N2G6
RGDFAYAAPAPPDGA

DUX4L2

236

P0CJ85
PEEAFFSVASPEPAG

KIAA1522

731

Q9P206
AGFTPFANGPDDTPE

RPS6KA2

606

Q15349
AAFPLESADPAGVAP

NACA

646

E9PAV3
FFDKGAVNGFDPAPP

NDEL1

311

Q9GZM8
DFSPPFRFGTVPNGS

GRIN2B

676

Q13224