Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of postsynaptic actin cytoskeleton

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

2.82e-13111447GO:0098973
GeneOntologyMolecularFunctionstructural constituent of postsynapse

RAPSN POTEF ACTBL2 SPTBN2 ACTB ACTG1 POTEKP POTEE POTEI

9.98e-13321449GO:0099186
GeneOntologyMolecularFunctionstructural constituent of synapse

RAPSN POTEF ACTBL2 SPTBN2 ACTB ACTG1 POTEKP POTEE POTEI

1.49e-11421449GO:0098918
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

POTEF ACTBL2 SPTBN2 ACTB ACTG1 POTEKP EPB41L3 POTEE POTEI

4.31e-071301449GO:0005200
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2

1.54e-0431442GO:0005220
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

RAPSN SYNE1 EPB41L3 SYNE2

3.07e-04451444GO:0043495
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

5.09e-0451442GO:0140444
GeneOntologyBiologicalProcesspostsynaptic actin cytoskeleton organization

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

1.67e-09311457GO:0098974
GeneOntologyBiologicalProcesspostsynaptic cytoskeleton organization

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

4.18e-09351457GO:0099188
GeneOntologyBiologicalProcesspostsynapse organization

RAPSN POTEF ACTBL2 SPTBN2 ACTB CKAP5 ACTG1 POTEKP LRRC4 POTEE MFN2 POTEI

2.26e-0631314512GO:0099173
GeneOntologyBiologicalProcessinner cell mass cell differentiation

LATS1 TET1 NLE1

1.86e-0581453GO:0001826
GeneOntologyBiologicalProcesssynapse organization

RAPSN LRRN1 SEMA7A POTEF ACTBL2 SPTBN2 ACTB CKAP5 ACTG1 POTEKP LRRC4 LRIT3 POTEE TENM4 MFN2 POTEI

2.66e-0568514516GO:0050808
GeneOntologyBiologicalProcesssynaptic vesicle endocytosis

ACTB ACTG1 FCHO2 SYNJ2 AP3D1 CXADR

6.00e-05961456GO:0048488
GeneOntologyBiologicalProcesspresynaptic endocytosis

ACTB ACTG1 FCHO2 SYNJ2 AP3D1 CXADR

8.42e-051021456GO:0140238
GeneOntologyBiologicalProcesssynaptic vesicle recycling

ACTB ACTG1 FCHO2 SYNJ2 AP3D1 CXADR

1.34e-041111456GO:0036465
GeneOntologyBiologicalProcesstransepithelial transport

ACTB ACTG1 ITPR1 CXADR

1.44e-04381454GO:0070633
GeneOntologyBiologicalProcesscell junction organization

RAPSN LRRN1 SEMA7A POTEF ACTBL2 SPTBN2 ACTB CKAP5 ACTG1 POTEKP EPB41L3 LRRC4 LRIT3 POTEE TENM4 MFN2 POTEI CXADR

1.69e-0497414518GO:0034330
GeneOntologyCellularComponentNuA4 histone acetyltransferase complex

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

1.85e-09321447GO:0035267
GeneOntologyCellularComponentH4/H2A histone acetyltransferase complex

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

1.85e-09321447GO:0043189
GeneOntologyCellularComponentH4 histone acetyltransferase complex

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

2.32e-08451447GO:1902562
GeneOntologyCellularComponenthistone acetyltransferase complex

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

3.95e-06941447GO:0000123
GeneOntologyCellularComponentblood microparticle

POTEF ACTB ACTG1 ACTG2 POTEE PZP EIF2A HBE1

7.13e-061441448GO:0072562
GeneOntologyCellularComponentprotein acetyltransferase complex

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

7.74e-061041447GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

1.05e-051091447GO:1902493
GeneOntologyCellularComponentsupramolecular fiber

POTEF SYNE1 ACTBL2 ACTB TOGARAM2 CKAP5 RIBC1 ACTG1 ACTG2 POTEKP DNAH1 POTEE KIF2B SYNJ2 UNC45B SYNE2 KIF14 POTEI SPAG17 DNAH6 DCTN3

5.86e-05117914421GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

POTEF SYNE1 ACTBL2 ACTB TOGARAM2 CKAP5 RIBC1 ACTG1 ACTG2 POTEKP DNAH1 POTEE KIF2B SYNJ2 UNC45B SYNE2 KIF14 POTEI SPAG17 DNAH6 DCTN3

6.45e-05118714421GO:0099081
GeneOntologyCellularComponentactin filament

POTEF ACTBL2 ACTB ACTG1 POTEKP POTEE POTEI

6.95e-051461447GO:0005884
GeneOntologyCellularComponenttransferase complex

DCAF1 METTL3 RBBP4 POTEF ACTBL2 ACTB ACTG1 CUL9 POTEKP MAGT1 FBXL5 PIK3R4 POTEE TRMT10C FBXO39 POTEI BECN1 TAF1L

1.14e-0496314418GO:1990234
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

POTEF ACTBL2 ACTB TOGARAM2 CKAP5 RIBC1 ACTG1 POTEKP DNAH1 POTEE KIF2B SYNJ2 KIF14 POTEI SPAG17 DNAH6 DCTN3

1.56e-0489914417GO:0099513
GeneOntologyCellularComponentactin cytoskeleton

ACACA POTEF ACTBL2 SPTBN2 ACTB ACTG1 ACTG2 POTEKP POTEE TTC17 POTEI SEPTIN12 DCTN3

1.80e-0457614413GO:0015629
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III, type II

PIK3R4 BECN1

2.80e-0441442GO:0034272
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III, type I

PIK3R4 BECN1

2.80e-0441442GO:0034271
GeneOntologyCellularComponentpostsynaptic cytoskeleton

SPTBN2 ACTB ACTG1

7.41e-04261443GO:0099571
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III

PIK3R4 BECN1

9.67e-0471442GO:0035032
GeneOntologyCellularComponentdense body

ACTB ACTG1

9.67e-0471442GO:0097433
GeneOntologyCellularComponentintracellular protein-containing complex

DCAF1 POTEF ACTBL2 ACTB ACTG1 CUL9 POTEKP ECPAS ELMO1 FBXL5 ITPR1 POTEE TRMT10C FBXO39 POTEI TAF1L

1.10e-0397214416GO:0140535
GeneOntologyCellularComponentchromatin

SOX6 MNX1 RBBP4 POTEF ACTBL2 PARG ACTB YY2 ACTG1 POTEKP RFX8 FANCC POTEE HOXB3 TET1 EHF SUPT16H ANKRD17 POTEI TAF1L TOP2B

1.24e-03148014421GO:0000785
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2

1.64e-0391442GO:0031095
GeneOntologyCellularComponentcalyx of Held

ACTB ACTG1 KCNK2

1.94e-03361443GO:0044305
GeneOntologyCellularComponentinner dynein arm

DNAH1 DNAH6

2.05e-03101442GO:0036156
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

2.49e-03111442GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

2.49e-03111442GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

2.49e-03111442GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

2.49e-03111442GO:0034993
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2

2.49e-03111442GO:0031094
GeneOntologyCellularComponentnuclear outer membrane

SYNE1 SYNE2 UGT2B4

2.62e-03401443GO:0005640
GeneOntologyCellularComponentaxon

TRPM7 POTEF ACTBL2 ACTB ACTG1 POTEKP EPB41L3 ITPR2 POTEE SYNJ2 KCNK2 POTEI AP3D1 CXADR

3.43e-0389114414GO:0030424
DomainActin_CS

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

1.44e-11161437IPR004001
DomainACTINS_2

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

2.43e-11171437PS00432
DomainActin/actin-like_CS

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

3.95e-11181437IPR020902
DomainACTINS_ACT_LIKE

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

6.21e-11191437PS01132
DomainActin

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

3.00e-09311437IPR004000
DomainActin

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

3.00e-09311437PF00022
DomainACTIN

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

3.00e-09311437SM00268
DomainACTINS_1

ACTBL2 ACTB ACTG1 ACTG2

2.25e-0781434PS00406
DomainARM-type_fold

DCAF1 TOGARAM2 CKAP5 CUL9 ECPAS ELMO1 ITPR1 ITPR2 PIK3R4 UNC45B STKLD1 TARBP1 AP3D1 KPNA2

3.48e-0733914314IPR016024
DomainARM-like

DCAF1 TOGARAM2 CKAP5 CUL9 ECPAS ELMO1 PIK3R4 UNC45B STKLD1 TARBP1 AP3D1 KPNA2

1.16e-0627014312IPR011989
Domain-

DCAF1 TOGARAM2 CKAP5 CUL9 ECPAS ELMO1 PIK3R4 UNC45B AP3D1 KPNA2

8.29e-06222143101.25.10.10
DomainInsP3_rcpt-bd

ITPR1 ITPR2

1.74e-0431432IPR000493
DomainKASH

SYNE1 SYNE2

3.46e-0441432IPR012315
DomainKASH

SYNE1 SYNE2

3.46e-0441432PS51049
DomainCLASP_N

TOGARAM2 CKAP5

3.46e-0441432PF12348
DomainCLASP_N_dom

TOGARAM2 CKAP5

3.46e-0441432IPR024395
DomainKASH

SYNE1 SYNE2

3.46e-0441432SM01249
DomainKASH

SYNE1 SYNE2

3.46e-0441432PF10541
DomainG-protein_beta_WD-40_rep

RBBP4 WDR88 SMU1 NLE1 WDR49

4.92e-04851435IPR020472
DomainTPR_repeat

P4HA2 RAPSN TTC3 UNC45B TTC17 TTC13

5.60e-041331436IPR019734
DomainCPSASE_1

ACACA CPS1

5.73e-0451432PS00866
DomainTPR_2

P4HA2 TTC3 TTC17 TTC13

5.77e-04501434PF07719
DomainTPR_2

P4HA2 TTC3 TTC17 TTC13

5.77e-04501434IPR013105
DomainTPR_1

RAPSN TTC3 UNC45B TTC17 TTC13

6.40e-04901435IPR001440
DomainTPR_1

RAPSN TTC3 UNC45B TTC17 TTC13

6.40e-04901435PF00515
DomainSpectrin

SYNE1 SPTBN2 SYNE2

6.96e-04231433PF00435
DomainACTININ_2

SYNE1 SPTBN2 SYNE2

6.96e-04231433PS00020
DomainACTININ_1

SYNE1 SPTBN2 SYNE2

6.96e-04231433PS00019
DomainActinin_actin-bd_CS

SYNE1 SPTBN2 SYNE2

6.96e-04231433IPR001589
DomainRIH_assoc-dom

ITPR1 ITPR2

8.56e-0461432IPR013662
DomainIns145_P3_rec

ITPR1 ITPR2

8.56e-0461432PF08709
DomainRIH_assoc

ITPR1 ITPR2

8.56e-0461432PF08454
DomainRIH_dom

ITPR1 ITPR2

8.56e-0461432IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2

8.56e-0461432IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2

8.56e-0461432IPR015925
DomainCPSASE_2

ACACA CPS1

8.56e-0461432PS00867
Domain-

ITPR1 ITPR2

8.56e-04614321.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2

8.56e-0461432PF01365
DomainTPR-contain_dom

P4HA2 RAPSN TTC3 UNC45B TTC17 TTC13

1.05e-031501436IPR013026
Domain-

DCAF1 SEMA7A RBBP4 WDR88 PIK3R4 SMU1 NLE1 EIF2A WDR49

1.08e-0333314392.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF1 SEMA7A RBBP4 WDR88 PIK3R4 SMU1 NLE1 EIF2A WDR49

1.12e-033351439IPR015943
DomainCbamoylP_synth_lsu-like_ATP-bd

ACACA CPS1

1.19e-0371432IPR005479
DomainBC-like_N

ACACA CPS1

1.19e-0371432IPR005481
DomainCPSase_L_D2

ACACA CPS1

1.19e-0371432PF02786
DomainBiotin_carb_N

ACACA CPS1

1.19e-0371432PF00289
DomainWD_REPEATS_1

DCAF1 RBBP4 WDR88 PIK3R4 SMU1 NLE1 EIF2A WDR49

1.37e-032781438PS00678
DomainSpectrin_repeat

SYNE1 SPTBN2 SYNE2

1.39e-03291433IPR002017
DomainWD_REPEATS_2

DCAF1 RBBP4 WDR88 PIK3R4 SMU1 NLE1 EIF2A WDR49

1.40e-032791438PS50082
DomainWD_REPEATS_REGION

DCAF1 RBBP4 WDR88 PIK3R4 SMU1 NLE1 EIF2A WDR49

1.40e-032791438PS50294
DomainWD40_repeat_CS

RBBP4 WDR88 PIK3R4 SMU1 NLE1 WDR49

1.66e-031641436IPR019775
DomainTPR_REGION

P4HA2 RAPSN TTC3 UNC45B TTC17 TTC13

1.71e-031651436PS50293
DomainTPR

P4HA2 RAPSN TTC3 UNC45B TTC17 TTC13

1.71e-031651436PS50005
DomainSPEC

SYNE1 SPTBN2 SYNE2

1.85e-03321433SM00150
DomainSpectrin/alpha-actinin

SYNE1 SPTBN2 SYNE2

1.85e-03321433IPR018159
DomainHEAT_REPEAT

CKAP5 ECPAS PIK3R4 AP3D1

2.04e-03701434PS50077
DomainWD40_repeat_dom

DCAF1 RBBP4 WDR88 PIK3R4 SMU1 NLE1 EIF2A WDR49

2.08e-032971438IPR017986
DomainCH

SYNE1 SPEF2 SPTBN2 SYNE2

2.38e-03731434PS50021
DomainMIR

ITPR1 ITPR2

2.52e-03101432PF02815
DomainMIR_motif

ITPR1 ITPR2

2.52e-03101432IPR016093
DomainMIR

ITPR1 ITPR2

2.52e-03101432PS50919
DomainMIR

ITPR1 ITPR2

2.52e-03101432SM00472
DomainCH-domain

SYNE1 SPEF2 SPTBN2 SYNE2

2.63e-03751434IPR001715
DomainTPR

RAPSN TTC3 UNC45B TTC17 TTC13

3.16e-031291435SM00028
Domain-

ACACA CPS1

4.30e-031314323.40.50.20
DomainDynein_heavy_chain_D4_dom

DNAH1 DNAH6

4.99e-03141432IPR024317
DomainDynein_HC_stalk

DNAH1 DNAH6

4.99e-03141432IPR024743
DomainDynein_heavy_dom-2

DNAH1 DNAH6

4.99e-03141432IPR013602
DomainDHC_N2

DNAH1 DNAH6

4.99e-03141432PF08393
DomainATPase_dyneun-rel_AAA

DNAH1 DNAH6

4.99e-03141432IPR011704
DomainATP_GRASP

ACACA CPS1

4.99e-03141432PS50975
DomainATP-grasp

ACACA CPS1

4.99e-03141432IPR011761
DomainPreATP-grasp_dom

ACACA CPS1

4.99e-03141432IPR016185
DomainMT

DNAH1 DNAH6

4.99e-03141432PF12777
DomainAAA_8

DNAH1 DNAH6

4.99e-03141432PF12780
DomainAAA_5

DNAH1 DNAH6

4.99e-03141432PF07728
Domain-

P4HA2 RAPSN TTC3 UNC45B TTC17 TTC13

5.25e-0320714361.25.40.10
DomainDHC_fam

DNAH1 DNAH6

5.73e-03151432IPR026983
DomainDynein_heavy

DNAH1 DNAH6

5.73e-03151432PF03028
DomainDynein_heavy_dom

DNAH1 DNAH6

5.73e-03151432IPR004273
Domain-

ACACA CPS1

5.73e-031514323.30.1490.20
DomainHEAT

CKAP5 ECPAS PIK3R4

5.91e-03481433PF02985
DomainVWF_type-D

MUC19 VWDE

6.51e-03161432IPR001846
DomainVWFD

MUC19 VWDE

6.51e-03161432PS51233
DomainVWD

MUC19 VWDE

6.51e-03161432SM00216
DomainVWD

MUC19 VWDE

6.51e-03161432PF00094
DomainCarboxyPept-like_regulatory

CPXM2 TENM4

7.34e-03171432IPR008969
DomainHEAT_type_2

CKAP5 PIK3R4

7.34e-03171432IPR021133
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

SPTBN2 ITPR1 ITPR2

3.02e-0510913M47661
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTBN2 ACTB ACTG1

3.02e-0510913MM15112
Pubmed

Identification of a novel actin isoform in hepatocellular carcinoma.

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEKP POTEE POTEI

5.27e-1615147816824795
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCAF1 NUP107 TRPM7 RBBP4 SYNE1 SPTBN2 MAGT1 RRM1 EPB41L3 TTC3 NDUFS1 LACTB ITPR1 ITPR2 TRMT10C PRCC TRABD SYNE2 SUPT16H SMU1 NLE1 TTC17 TTC13 EIF2A AP3D1 TOP2B CXADR HERC5

2.71e-1114871472833957083
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DCAF1 ACACA NUP107 ACTB CKAP5 ECPAS SUPT16H XRN1 ANKRD17 TTC17 AP3D1 TOP2B

7.17e-112021471233005030
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ACACA NUP107 RBBP4 SPTBN2 CKAP5 CUL9 MCM6 ECPAS EPB41L3 TTF1 NDUFS1 SYNE2 XRN1 SMU1 KIF14 ANKRD17 NLE1 HERC5

3.82e-106531471822586326
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

ACACA NUP107 RBBP4 COG7 ACTB CKAP5 MCM6 RRM1 ECPAS NDUFS1 SUPT16H SMU1 AP3D1 TOP2B KPNA2

9.68e-086381471533239621
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TTF2 ACACA VPS13C KIAA0232 SPTBN2 CKAP5 RIBC1 ACTG1 FCHO2 ECPAS LATS1 SYNJ2 XRN1 KIF14 TTC17 EIF2A DCTN3

1.38e-078531471728718761
Pubmed

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.

POTEF RPS6KA1 ACTBL2 ACTB ACTG1 ACTG2 POTEKP FCHO2 POTEE HBE1

1.54e-072561471024189400
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ACACA TRPM7 POTEF KIAA0232 CKAP5 EPB41L3 PIK3R4 LATS1 SYNJ2 SYNE2 TET1 XRN1 KIF14 ANKRD17 PLEKHA2 BECN1 BICC1

1.57e-078611471736931259
Pubmed

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.

POTEF ACTB ACTG1 ACTG2 FRMD4B POTEE POTEI

1.82e-0796147723580065
Pubmed

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.

POTEF ACTB ACTG1 ACTG2 POTEE PZP EIF2A HBE1

1.85e-07143147822516433
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

POTEF SYNE1 SPEF2 ACTBL2 SPTBN2 ACTB ACTG1 ACTG2 EPB41L3 TTC3 NDUFS1 POTEE LATS1 SYNE2 SUPT16H XRN1 NLE1 POTEI SPAG17 DNAH6 AP3D1 TOP2B

1.89e-0714421472235575683
Pubmed

Regulating the functions of the HIV-1 matrix protein.

ACTB ACTG1 ACTG2 KPNA2

2.97e-0714147417411366
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

TTF2 NUP107 TRPM7 VPS13C SYNE1 ACTBL2 TACC2 MAGT1 TTC3 GTPBP10 NDUFS1 LACTB ITPR1 ITPR2 POTEE TRMT10C TRABD SYNE2 SUPT16H MFN2 TTC17 TTC13

3.53e-0714961472232877691
Pubmed

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ.

ACTBL2 ACTB ACTG1 PKD1L3 AP3D1

7.36e-0740147527197753
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DCAF1 TTF2 ACACA NUP107 RBBP4 ACTB CKAP5 MCM6 RRM1 EPB41L3 NDUFS1 PIK3R4 SUPT16H XRN1 SMU1 ANKRD17 NLE1 EIF2A AP3D1 TOP2B

1.18e-0613531472029467282
Pubmed

Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.

ACTB ACTG1 ACTG2

1.47e-06614739971772
Pubmed

Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.

ACTB ACTG1 ACTG2

1.47e-066147310074138
Pubmed

Virus assembly and plasma membrane domains: which came first?

ACTB ACTG1 ACTG2

1.47e-066147322989508
Pubmed

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.

ACTB ACTG1 ACTG2

1.47e-06614731540415
Pubmed

HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.

ACTB ACTG1 ACTG2

1.47e-066147311709093
Pubmed

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.

ACTB ACTG1 ACTG2

1.47e-066147310049817
Pubmed

Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.

ACTB ACTG1 ACTG2

1.47e-066147312009869
Pubmed

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

ACTB ACTG1 ACTG2

1.47e-066147323811015
Pubmed

Retroviral assembly and budding occur through an actin-driven mechanism.

ACTB ACTG1 ACTG2

1.47e-066147319883584
Pubmed

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

ACTB ACTG1 ACTG2

1.47e-066147321917091
Pubmed

HIV-1 Gag protein associates with F-actin present in microfilaments.

ACTB ACTG1 ACTG2

1.47e-06614738661406
Pubmed

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

ACTB ACTG1 ACTG2

1.47e-066147323017337
Pubmed

Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.

ACTB ACTG1 ACTG2

1.47e-066147323875777
Pubmed

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.

ACTB ACTG1 ACTG2

1.47e-06614739841925
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NUP107 RBBP4 SYNE1 ACTBL2 SPTBN2 CKAP5 ACTG1 MCM6 ITPR2 SYNE2 SUPT16H SMU1 KIF14 NLE1 TOP2B CXADR KPNA2

1.71e-0610241471724711643
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

TTF2 CTNNAL1 CKAP5 MAGT1 FCHO2 RRM1 ECPAS EPB41L3 LATS1 XRN1 ANKRD17 EIF2A AP3D1 KPNA2

2.04e-067081471439231216
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

RBBP4 POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEKP NDUFS1 POTEE TBC1D12 XRN1 SPAG17

2.07e-065131471225798074
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

ACACA RBBP4 CKAP5 ACTG1 MAGT1 CPS1 RRM1 EPB41L3 VWDE NDUFS1 FBXL5 TTC17 TTC13

2.25e-066131471322268729
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEKP POTEE POTEI TOP2B

2.50e-06271147932433965
Pubmed

Essential and supporting host cell factors for HIV-1 budding.

ACTB ACTG1 ACTG2 AP3D1

2.55e-0623147422004035
Pubmed

The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.

ACTB ACTG1 ACTG2

2.56e-067147322535526
Pubmed

Selective targeting of ITK blocks multiple steps of HIV replication.

ACTB ACTG1 ACTG2

2.56e-067147318443296
Pubmed

The trinity of the cortical actin in the initiation of HIV-1 infection.

ACTB ACTG1 ACTG2

2.56e-067147322640593
Pubmed

HIV-1 replication from after cell entry to the nuclear periphery.

ACTB ACTG1 ACTG2

2.56e-067147317504171
Pubmed

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

ACTB ACTG1 ACTG2

2.56e-067147322465675
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

RBBP4 COG7 ACTBL2 SPTBN2 FCHO2 RRM1 ECPAS GTPBP10 NDUFS1 ITPR1 ITPR2 TRMT10C SYNE2 SUPT16H SMU1 KIF14 AP3D1 TOP2B HERC5 KPNA2

3.02e-0614401472030833792
Pubmed

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

POTEF ACTBL2 SPTBN2 ACTB POTEE POTEI EIF2A

3.55e-06149147722664934
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

TTF2 NUP107 PARG CKAP5 CUL9 MCM6 MAGT1 CPS1 ECPAS TTF1 LACTB ANKRD17 TOP2B HERC5 KPNA2

3.85e-068571471525609649
Pubmed

Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

ACTB ACTG1 ACTG2

4.08e-068147314694110
Pubmed

Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.

ACTB ACTG1 ACTG2

4.08e-068147320147394
Pubmed

Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.

ACTB ACTG1 ACTG2

4.08e-068147323260110
Pubmed

The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma.

POTEF ACTB ACTG1 POTEKP POTEE SERPINB5

4.42e-06100147621800051
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RBBP4 CKAP5 TACC2 TTF1 GTPBP10 PIK3R4 SUPT16H XRN1 NLE1 BECN1 AP3D1 TOP2B HERC5 KPNA2

4.54e-067591471435915203
Pubmed

Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.

ACTB ACTG1 ACTG2

6.10e-069147310556093
Pubmed

Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.

POTEKP POTEE POTEI

6.10e-069147316364570
Pubmed

Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.

ACTB ACTG1 ACTG2

6.10e-06914738892894
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

ACTB ACTG1 ACTG2

6.10e-069147318775311
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TTF2 METTL3 EPS8L2 NUP107 RBBP4 DTYMK ACTB CKAP5 EPB41L3 PIK3R4 PRCC KPNA2

7.45e-065821471220467437
Pubmed

Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.

ACTB ACTG1 ACTG2

8.69e-061014731907279
Pubmed

Non-viral cellular substrates for human immunodeficiency virus type 1 protease.

ACTB ACTG1 ACTG2

8.69e-061014731991513
Pubmed

Gelsolin activity controls efficient early HIV-1 infection.

ACTB ACTG1 ACTG2

8.69e-0610147323575248
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

ACACA ACTBL2 ACTB CKAP5 ACTG1 MCM6 TACC2 CPS1 RRM1 GTPBP10 TRMT10C SYNE2 SUPT16H SMU1 EIF2A TARBP1 AP3D1 TOP2B KPNA2

8.81e-0614151471928515276
Pubmed

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.

ACACA ACTBL2 ACTB CKAP5 SUPT16H KIF14 EIF2A AP3D1 TOP2B

8.88e-06317147930997501
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ACACA NUP107 RBBP4 VPS13C SYNE1 CKAP5 ACTG1 MCM6 ECPAS EPB41L3 TTC3 NDUFS1 PIK3R4 TRMT10C SUPT16H SMU1 KIF14 TOP2B KPNA2

9.72e-0614251471930948266
Pubmed

EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3.

ACACA ACTBL2 ACTB CKAP5 ACTG1 POTEE KPNA2

9.83e-06174147735031058
Pubmed

CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.

ACTB ACTG1 ACTG2

1.19e-0511147330962377
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

ACTB ACTG1 ACTG2

1.19e-0511147323294842
Pubmed

Quantitative proteomic analysis of lentiviral vectors using 2-DE.

ACTB ACTG1 ACTG2

1.19e-0511147319639585
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ACACA NUP107 CKAP5 ECPAS EPB41L3 TET1 XRN1 KIF14 ANKRD17 PLEKHA2

1.24e-054181471034709266
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

TTF2 ACACA MCM6 NDUFS1 SUPT16H XRN1 MFN2

1.32e-05182147732239614
Pubmed

Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.

ACACA NUP107 CKAP5 MCM6 KPNA2

1.40e-0572147536376293
Pubmed

HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.

ACTB ACTG1 ACTG2

1.58e-0512147323071112
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ACACA VPS13C NEXMIF SPTBN2 CKAP5 MUC19 ECPAS ITPR2 SLC6A6 POTEE TBC1D14 CCDC87 ARHGAP20

1.59e-057361471329676528
Pubmed

Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.

ACTB ACTG1

1.77e-052147221778137
Pubmed

De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.

ACTB ACTG1

1.77e-052147222366783
Pubmed

The simultaneous downregulation of TRPM7 and MagT1 in human mesenchymal stem cells in vitro: Effects on growth and osteogenic differentiation.

TRPM7 MAGT1

1.77e-052147230952425
Pubmed

Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.

ACTB ACTG1

1.77e-052147232588558
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

1.77e-052147211792814
Pubmed

Baraitser-Winter cerebrofrontofacial syndrome.

ACTB ACTG1

1.77e-052147227625340
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

1.77e-052147224931616
Pubmed

TRPM7 and MagT1 in the osteogenic differentiation of human mesenchymal stem cells in vitro.

TRPM7 MAGT1

1.77e-052147230385806
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

1.77e-052147215201137
Pubmed

Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1.

BECN1 HERC5

1.77e-052147232093773
Pubmed

A primate-specific POTE-actin fusion protein plays a role in apoptosis.

POTEF POTEE

1.77e-052147219669888
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

1.77e-052147223582047
Pubmed

Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.

ACTB ACTG1

1.77e-05214723221869
Pubmed

The Mg2+ transporter MagT1 partially rescues cell growth and Mg2+ uptake in cells lacking the channel-kinase TRPM7.

TRPM7 MAGT1

1.77e-052147221627970
Pubmed

TRPM7 and MagT1 regulate the proliferation of osteoblast-like SaOS-2 cells through different mechanisms.

TRPM7 MAGT1

1.77e-052147232633723
Pubmed

Identification and developmental expression of a smooth-muscle gamma-actin in postmeiotic male germ cells of mice.

ACTG1 ACTG2

1.77e-05214722747639
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

1.77e-052147219120126
Pubmed

Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.

ACTB ACTG1

1.77e-052147221502360
Pubmed

The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.

ACTB ACTG1

1.77e-05214726686106
Pubmed

Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.

ACTB ACTG1

1.77e-0521472213279
Pubmed

The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.

ACTB ACTG1

1.77e-052147233334799
Pubmed

β-Actin specifically controls cell growth, migration, and the G-actin pool.

ACTB ACTG1

1.77e-052147221900491
Pubmed

METTL3 confers protection against mitochondrial dysfunction and cognitive impairment in an Alzheimer disease mouse model by upregulating Mfn2 via N6-methyladenosine modification.

METTL3 MFN2

1.77e-052147238408379
Pubmed

Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.

ACTB ACTG1

1.77e-052147219638415
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

1.77e-052147222768332
Pubmed

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

ITPR1 BECN1

1.77e-052147219325567
Pubmed

Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.

ACTB ACTG1

1.77e-05214723335520
Pubmed

Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.

ACTB ACTG1

1.77e-05214729288906
Pubmed

High level expression of transfected beta- and gamma-actin genes differentially impacts on myoblast cytoarchitecture.

ACTB ACTG1

1.77e-05214721577857
Pubmed

Baraitser-Winter Cerebrofrontofacial Syndrome

ACTB ACTG1

1.77e-052147226583190
Pubmed

Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation.

ACTB ACTG1

1.77e-052147232326615
Pubmed

Interaction of the Coxsackie and adenovirus receptor (CAR) with the cytoskeleton: binding to actin.

ACTB CXADR

1.77e-052147217531226
InteractionPOTEJ interactions

ACTBL2 ACTB ACTG1 ACTG2 CUL9 POTEE KIF14 POTEI

3.05e-09521438int:POTEJ
InteractionLRRC31 interactions

DCAF1 ACACA NUP107 ACTB CKAP5 ECPAS SUPT16H XRN1 ANKRD17 TTC17 AP3D1 TOP2B

2.63e-0820514312int:LRRC31
InteractionACTG2 interactions

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

5.23e-08491437int:ACTG2
InteractionSIRT7 interactions

DCAF1 ACACA NUP107 RBBP4 SPTBN2 CKAP5 CUL9 MCM6 ECPAS EPB41L3 TTF1 NDUFS1 SYNE2 XRN1 SMU1 KIF14 ANKRD17 NLE1 HERC5

1.37e-0674414319int:SIRT7
InteractionSCIN interactions

POTEF ACTBL2 ACTB CKAP5 ACTG1 POTEI

3.43e-06581436int:SCIN
InteractionFBXO32 interactions

METTL3 ACACA NUP107 ACTBL2 ACTB CKAP5 ACTG1 GTPBP10 LACTB SERPINB5 SMU1 EIF2A HERC5

3.86e-0638614313int:FBXO32
InteractionPOTEE interactions

ACTBL2 ACTB ACTG1 ACTG2 POTEE KIF14 POTEI CXADR

5.18e-061341438int:POTEE
InteractionCDC42 interactions

CTNNAL1 ACACA TRPM7 SYNE1 SPTBN2 ACTB MCM6 MAGT1 FCHO2 RRM1 ECPAS EPB41L3 NDUFS1 ITPR1 ITPR2 SLC6A6 TRMT10C TRABD SYNE2 KIF14 ARHGAP20 AP3D1 TOP2B CXADR KPNA2

6.26e-06132314325int:CDC42
InteractionACTBL2 interactions

NUP107 POTEF ACTBL2 ACTB ACTG1 ACTG2 FBXL5 POTEE MFN2 POTEI DCTN3

8.84e-0629614311int:ACTBL2
InteractionERRFI1 interactions

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEKP POTEE

1.13e-051071437int:ERRFI1
InteractionDCTN1 interactions

TTF2 SPTBN2 ACTB CKAP5 ACTG1 MCM6 ECPAS FBXL5 SYNJ2 SUPT16H KIF14 EIF2A DCTN3 KPNA2

1.25e-0549714314int:DCTN1
InteractionACTA1 interactions

EPS8L2 POTEF ACTBL2 SPTBN2 ACTB ACTG1 ACTG2 ITPR1 POTEE LATS1 POTEI DNAH6

1.39e-0537114312int:ACTA1
InteractionDEFA6 interactions

ACTBL2 ACTB POTEE PZP

1.94e-05231434int:DEFA6
InteractionRNF217 interactions

ACTBL2 POTEKP ECPAS

2.85e-0591433int:RNF217
InteractionACTC1 interactions

METTL3 POTEF SYNE1 ACTBL2 ACTB ACTG1 ACTG2 CUL9 POTEE PRCC SYNE2 SMU1 KIF14 TTC17 POTEI KPNA2

3.46e-0569414316int:ACTC1
InteractionHDAC1 interactions

SOX6 DCAF1 METTL3 ACACA NUP107 TRPM7 RBBP4 PLEKHG7 ACTB CKAP5 ECPAS EPB41L3 SERPINB5 SYNE2 TET1 XRN1 KIF14 ANKRD17 TOP2B HERC5 KPNA2

3.64e-05110814321int:HDAC1
InteractionPHACTR2 interactions

ACTBL2 ACTB ACTG1 POTEI

5.03e-05291434int:PHACTR2
InteractionWASH8P interactions

ACTBL2 ACTB POTEKP

5.54e-05111433int:WASH8P
InteractionDMD interactions

CTNNAL1 SYNE1 FCHO2 LPAR6 SYNE2 KIF14 PLEKHA2

6.69e-051411437int:DMD
InteractionDCTN4 interactions

ACACA RBBP4 ACTB ACTG1 ECPAS DCTN3 KPNA2

7.31e-051431437int:DCTN4
InteractionGC interactions

POTEF ACTBL2 ACTB POTEKP POTEI

7.84e-05621435int:GC
InteractionTWF2 interactions

POTEF ACTBL2 ACTB ACTG1 CCDC87 KIF14

7.92e-051001436int:TWF2
InteractionPDCL3 interactions

POTEF ACTBL2 ACTB ACTG1 KIF14 POTEI

7.92e-051001436int:PDCL3
InteractionRHOF interactions

TRPM7 SPTBN2 ACTB MAGT1 FCHO2 ECPAS EPB41L3 SLC6A6 POTEE TRMT10C TRABD SUPT16H KIF14 TOP2B CXADR

8.99e-0567314315int:RHOF
InteractionITSN1 interactions

TRPM7 RBBP4 SYNE1 ACTBL2 ACTB ACTG1 FCHO2 SYNJ2 BECN1

9.93e-052591439int:ITSN1
InteractionRHOT2 interactions

NUP107 TRPM7 VPS13C SYNE1 TACC2 NDUFS1 TRABD MFN2 KIF14 TTC17

1.01e-0432114310int:RHOT2
InteractionPOTEI interactions

ACTBL2 ACTB ACTG1 ACTG2 POTEE POTEI

1.04e-041051436int:POTEI
InteractionCAP2 interactions

POTEF ACTBL2 ACTB ACTG1 POTEI

1.06e-04661435int:CAP2
InteractionABRA interactions

ACTBL2 SPTBN2 ACTB POTEI

1.20e-04361434int:ABRA
InteractionRNASE3 interactions

ACTBL2 ACTB POTEI

1.20e-04141433int:RNASE3
InteractionNAA80 interactions

ACTBL2 ACTB POTEKP

1.50e-04151433int:NAA80
InteractionHSP90AB1 interactions

DCAF1 TTF2 METTL3 NUP107 RPS6KA1 SPEF2 ACTB CKAP5 ACTG1 SNRK MCM6 CPS1 SERPINB5 LATS1 UNC45B KIF14 SPAG17 KPNA2

1.58e-0496014318int:HSP90AB1
InteractionKIF20A interactions

P4HA2 RBBP4 SYNE1 SPTBN2 POTEKP CPS1 LACTB TRIM7 ITPR1 ITPR2 PCNX2 POTEE SYNE2 SUPT16H XRN1 SMU1 KIF14 TOP2B KPNA2

1.66e-04105214319int:KIF20A
InteractionC3orf18 interactions

CKAP5 MAGT1 ECPAS MFN2 KIF14 TARBP1

1.71e-041151436int:C3orf18
InteractionIFI16 interactions

NUP107 RBBP4 SYNE1 ACTB CKAP5 MCM6 GTPBP10 SUPT16H XRN1 SMU1 KIF14 NLE1 TOP2B HERC5 KPNA2

1.72e-0471414315int:IFI16
InteractionRHOBTB2 interactions

ACTG1 MCM6 NDUFS1 TRMT10C SUPT16H KIF14 TOP2B

1.79e-041651437int:RHOBTB2
InteractionPRC1 interactions

EPS8L2 NUP107 RBBP4 SYNE1 SPTBN2 MCM6 TACC2 POTEKP CPS1 NDUFS1 LACTB ITPR2 SUPT16H SMU1 KIF14 FBXO39 TOP2B KPNA2

1.86e-0497314318int:PRC1
InteractionPXK interactions

ACACA ACTBL2 ACTB ACTG1

2.01e-04411434int:PXK
InteractionEED interactions

DCAF1 P4HA2 EPS8L2 ACACA NUP107 RBBP4 VPS13C DTYMK RPS6KA1 ACTBL2 ACTB CKAP5 ACTG1 MCM6 MAGT1 RRM1 NDUFS1 UNC45B SUPT16H SMU1 HBE1 AP3D1 KPNA2

2.12e-04144514323int:EED
InteractionRCOR1 interactions

SOX6 ACACA NUP107 RBBP4 ACTB CKAP5 ECPAS EPB41L3 TET1 XRN1 ANKRD17 KPNA2

2.14e-0449414312int:RCOR1
InteractionACTA2 interactions

POTEF ACTBL2 ACTB ACTG1 ACTG2 POTEKP POTEE SERPINB5 POTEI DCTN3

2.28e-0435514310int:ACTA2
InteractionOBSL1 interactions

NUP107 RBBP4 SYNE1 ACTBL2 SPTBN2 CUL9 MCM6 PFKFB4 DNAH1 POTEE SYNE2 SUPT16H SMU1 KIF14 NLE1 TOP2B KPNA2

2.28e-0490214317int:OBSL1
InteractionCOBL interactions

ACTBL2 ACTB ACTG1 POTEKP KIF14

2.34e-04781435int:COBL
InteractionACTB interactions

TTF2 METTL3 RBBP4 COG7 POTEF ACTBL2 SPTBN2 ACTB ACTG1 ACTG2 POTEKP NDUFS1 FBXL5 POTEE KIF14 POTEI DNAH6 TOP2B HERC5

2.40e-04108314319int:ACTB
InteractionRNF123 interactions

ACACA PLEKHG7 VPS13C NEXMIF SPTBN2 CKAP5 MUC19 ACTG1 ECPAS ITPR2 SLC6A6 POTEE TBC1D14 CCDC87 ARHGAP20 HERC5

2.53e-0482414316int:RNF123
InteractionRHOG interactions

CTNNAL1 ACACA TRPM7 SPTBN2 MAGT1 FCHO2 EPB41L3 GTPBP10 NDUFS1 ELMO1 ITPR1 SLC6A6 TRMT10C TENM4 SYNE2 KIF14 CXADR

2.53e-0491014317int:RHOG
InteractionVDAC2 interactions

P4HA2 ACACA POTEF ACTB CUL9 MAGT1 NDUFS1 LATS1 KIF14 PLEKHA2 PZP

2.65e-0443214311int:VDAC2
InteractionPOU5F1 interactions

DCAF1 TTF2 DTYMK CKAP5 ACTG1 ECPAS TRMT10C TET1 SUPT16H ANKRD17 AP3D1 TOP2B KPNA2

2.73e-0458414313int:POU5F1
InteractionYAP1 interactions

TTF2 ACACA RBBP4 POTEF ACTBL2 SPTBN2 ACTB CKAP5 ACTG1 POTEKP POTEE LATS1 TET1 SUPT16H CCDC87 SMU1 KIF14 POTEI KPNA2

2.75e-04109514319int:YAP1
InteractionSTIP1 interactions

METTL3 ACACA NUP107 RBBP4 COG7 ACTB CKAP5 MCM6 RRM1 ECPAS NDUFS1 PIK3R4 SUPT16H SMU1 MFN2 AP3D1 TOP2B KPNA2

2.79e-04100614318int:STIP1
InteractionCEP152 interactions

TTF2 RRM1 ECPAS EPB41L3 LATS1 XRN1 KIF14

2.94e-041791437int:CEP152
InteractionRND2 interactions

TRPM7 MCM6 MAGT1 NDUFS1 ITPR1 TRMT10C SYNE2 SUPT16H KIF14 TOP2B CXADR

3.10e-0444014311int:RND2
InteractionCD274 interactions

DCAF1 ACACA NUP107 COG7 CKAP5 MCM6 MAGT1 RRM1 KIF14 KPNA2

3.10e-0436914310int:CD274
InteractionLRRC20 interactions

ACTBL2 ACTB POTEI

3.12e-04191433int:LRRC20
InteractionRAC2 interactions

CTNNAL1 TRPM7 ACTB MAGT1 FCHO2 NDUFS1 ITPR1 SLC6A6 POTEE TRMT10C SYNE2 KIF14 PLEKHA2 CXADR

3.20e-0467414314int:RAC2
Cytoband2q21.1

POTEF POTEKP POTEE POTEI

3.64e-055814642q21.1
CytobandEnsembl 112 genes in cytogenetic band chr2q21

POTEF MCM6 POTEKP POTEE POTEI

1.28e-041511465chr2q21
Cytoband11p11.2

RAPSN CKAP5 TTC17 OR4C5

1.48e-0483146411p11.2
Cytoband20p11.1

FAM182B FAM182A

6.49e-0412146220p11.1
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEF POTEKP POTEE POTEI

5.14e-0713964685
GeneFamilyActins

ACTB ACTG1 ACTG2

2.87e-066963929
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2

8.34e-053962297
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

1.66e-0449621252
GeneFamilySPOUT methyltranferase domain containing

TRMT10C TARBP1

7.65e-0489621294
GeneFamilyWD repeat domain containing

RBBP4 WDR88 PIK3R4 SMU1 NLE1 WDR49

2.73e-03262966362
GeneFamilyDyneins, axonemal

DNAH1 DNAH6

3.60e-0317962536
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

SOX6 TTF2 SEMA7A TRPM7 RBBP4 COG7 NEXMIF MAGT1 FRMD4B SLC6A6 TENM4 SYNE2 TET1 ANKRD17 ARHGAP20 HBE1 BICC1

2.14e-0580613917gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000

TRPM7 RBBP4 MAGT1 FRMD4B SLC6A6 TENM4 SYNE2 TET1 ARHGAP20

5.37e-052591399gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000

TRPM7 RBBP4 COG7 MAGT1 FRMD4B SLC6A6 TENM4 SYNE2 TET1 ARHGAP20

5.44e-0532313910gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500

TRPM7 RBBP4 FRMD4B SLC6A6 TENM4 SYNE2 TET1

5.98e-051501397gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000

P4HA2 TRPM7 RBBP4 ACTG2 RRM1 ECPAS EPB41L3 SERPINB5 LATS1 EHF TBC1D14 SUPT16H KCNK2 HBE1 BICC1 TOP2B

8.36e-0581113916gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000

TRPM7 RBBP4 MAGT1 FRMD4B SLC6A6 TENM4 SYNE2 TET1 ARHGAP20

8.98e-052771399gudmap_developingGonad_e12.5_ovary_k3_1000
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM7 VPS13C PARG CKAP5 FCHO2 SUPT16H XRN1 TOP2B

1.24e-071761468749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|(1)_Control_(PBS) / Stress and Cell class

CTNNAL1 SNRK ATP8B1 FCHO2 F8 UNC45B LPAR6 CXADR

2.42e-071921468e16e49b302019474232ef4cc0ff217d33afe34cf
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

CTNNAL1 SNRK ATP8B1 FCHO2 F8 UNC45B LPAR6 CXADR

2.73e-0719514686b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 SPEF2 TOGARAM2 LRRC4 SYNE2 SPAG17 DNAH6 WDR49

2.95e-07197146874a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

SPEF2 TACC2 SERPINB5 EHF SPAG17 DNAH6 WDR49

6.85e-0715114678216462e723fec2797387929dde095370947e10a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG7 SPEF2 TOGARAM2 SPAG17 PZP DNAH6 WDR49

1.46e-06169146714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEXMIF FCHO2 EPB41L3 PKD1L3 SERPINB5 EHF BICC1

1.84e-061751467f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DTYMK ACTB CKAP5 FBXL5 KIF14 DCTN3 KPNA2

2.14e-0617914676718cadcc2d3b64717ed84244ef1242d392662dc
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SOX6 SYNE1 USP29 RIBC1 SYNE2 POTEI

2.57e-0611814665f72022f4be3fb7ccec86dc05d37572833028886
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SOX6 SYNE1 USP29 RIBC1 SYNE2 POTEI

2.57e-061181466053c0986051e36fdc4c48b8067c137b6299b2f1b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DTYMK ACTB CKAP5 ACTG1 KIF14 DCTN3 KPNA2

2.66e-0618514676aeae77a087d695b1e58c5f63265e7113aa2e343
ToppCellControl-Lymphoid_T/NK-NK_activated|Control / Disease group, lineage and cell class

SOX6 SYNE1 USP29 RIBC1 SYNE2 POTEI

2.70e-061191466a258d91ac90d4174b6f203d7f96ba6e57c6003e7
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOX6 SYNE1 USP29 RIBC1 SYNE2 POTEI

2.70e-06119146628d6b0e9dda2fe4ca94ae9b95b7261618d0d9877
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOX6 SYNE1 USP29 RIBC1 SYNE2 POTEI

2.70e-0611914660fdd5b093ac20a4bda0f7b623808eb3ad0bf68e2
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

TTF2 SEMA7A TRPM7 VPS13C ITPR2 KIF14 TTC17

2.75e-0618614678571956890fc9894d766ba294a28e376b4aba428
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

DTYMK CKAP5 ACTG1 MCM6 RRM1 KIF14 KPNA2

3.28e-061911467210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX6 ACTB ACTG1 LXN FRMD4B HOXB3 ARHGAP20

3.76e-061951467c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 EPS8L2 TACC2 HOXB3 EHF BICC1 CXADR

3.89e-061961467c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CPXM2 TRIM7 SLC6A6 TENM4 ACOT11 EHF WDR49

4.44e-0620014678827653738a931e4a4545e0c7d75be12bed40740
ToppCellASK440-Epithelial|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

EPS8L2 SYNE1 TACC2 SYNE2 EHF SPAG17 CXADR

4.44e-062001467cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCellEndothelial-Endothelial-H_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

CKAP5 HOXB3 KIF14 DNAH6 SEPTIN12 KPNA2

6.36e-061381466a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

SYNE1 TOGARAM2 POTEE SYNE2 ARHGAP20 PARP15

1.28e-051561466afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PLEKHG7 SPEF2 TOGARAM2 SPAG17 PZP DNAH6

1.70e-0516414660e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG7 DNAH1 POTEI SPAG17 DNAH6 WDR49

1.95e-0516814669a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX6 MNX1 SPTBN2 SERPINB5 EHF KPNA2

1.95e-051681466f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEXMIF FCHO2 EPB41L3 PKD1L3 EHF BICC1

2.09e-051701466a121e10099faaeb60251eec162f38caf7c4238c2
ToppCelldroplet-Lung-LUNG-30m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 EHF STKLD1 SPAG17 PZP CXADR

2.62e-0517714667ac99ff16df94b4e08d361e3d98a7b3af8d6ee3b
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 EHF STKLD1 SPAG17 PZP CXADR

2.62e-051771466092a345cb802f183322aa5542341ba2d96d4f06a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C SYNE1 FCHO2 SYNE2 XRN1 HERC6

2.70e-05178146601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

TOGARAM2 RIBC1 LRRC4 SPAG17 PZP DNAH6

2.79e-0517914660e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 NEXMIF SPTBN2 MUC19 ITPR1 PLEKHA2

2.79e-051791466d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DTYMK CKAP5 FBXL5 KIF14 DCTN3 KPNA2

2.88e-051801466ed4966765a6b25456f68185cf0648c4a3a21d7fe
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLCXD2 SYNE1 ACTG1 SYNE2 TET1 PZP

2.97e-05181146612ff56fa2949c8d53360cdf2cacfd326e65b54aa
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTF2 DTYMK CKAP5 KCNK2 KIF14 KPNA2

3.16e-05183146629b62dd542bc3f8df843998f577724f3818d4271
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

TTF2 SEMA7A TRPM7 VPS13C KIF14 TTC17

3.35e-051851466a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

PLEKHG7 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

3.35e-05185146630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellfacs-Heart-LV-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8L2 SEMA7A ACTB SNRK SLC6A6 UNC45B

3.56e-0518714661bc338c22d645a854f8d8eb8a064c441121fb673
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

PLEKHG7 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

3.67e-05188146634b11f72ca73153d02edcd09b38983ad1a504659
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

NEXMIF SPTBN2 HOXB3 EHF SPAG17 BICC1

3.67e-0518814668f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SPEF2 TOGARAM2 RIBC1 SPAG17 DNAH6 WDR49

3.67e-0518814665ba5cbb403518026e9040379fb5d99339ea977d8
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG7 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

3.78e-051891466a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

ATP8B1 F8 FRMD4B ELMO1 ITPR1 ITPR2

3.78e-051891466c81787a8c662db5d7814c583dd64562857629e81
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

PLEKHG7 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

3.78e-051891466b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

PLEKHG7 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

3.78e-05189146627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L3 FRMD4B ELMO1 ITPR2 LPAR6 TBC1D14

3.89e-051901466f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

CTNNAL1 SNRK FCHO2 F8 UNC45B CXADR

3.89e-051901466ff083168d609957d00888f31b3488d6d56c902b4
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN ACTB ACTG1 TACC2 TTC3 LPAR6

3.89e-05190146684265be128170cbb08d76e824aa108e07da9c3e5
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C PARG ITPR2 SYNE2 ARHGAP20 TOP2B

4.01e-05191146660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRN1 ATP8B1 EPB41L3 SLC24A2 ACOT11 KPNA2

4.01e-051911466f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C PARG ITPR2 SYNE2 ARHGAP20 TOP2B

4.01e-051911466973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRN1 ATP8B1 EPB41L3 SLC24A2 ACOT11 KPNA2

4.13e-0519214665b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellASK452-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SYNE1 GTPBP10 CEACAM19 FKTN SYNE2 PARP15

4.13e-051921466f04ee5aaa54c39b7493098fb3d2f78168d6b8060
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49 BICC1

4.25e-0519314660e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

FCHO2 EPB41L3 FRMD4B ELMO1 ITPR2 TBC1D14

4.25e-051931466a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SYNE1 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

4.25e-051931466ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 SPEF2 TOGARAM2 TACC2 SPAG17 DNAH6

4.25e-051931466bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

RAPSN SEMA7A FAM78B TENM4 KCNK2 BICC1

4.25e-051931466035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPEF2 TOGARAM2 RIBC1 SPAG17 DNAH6 WDR49

4.37e-0519414661ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

4.37e-0519414664a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE1 SPEF2 TACC2 SYNE2 SPAG17 DNAH6

4.50e-051951466fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

FCHO2 EPB41L3 LRRC4 FRMD4B LPAR6 TBC1D12

4.50e-05195146610fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell18-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

SPEF2 TOGARAM2 RIBC1 SPAG17 DNAH6 WDR49

4.50e-0519514663441381759cd00d125752401dc99b78be1c78f88
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE1 SPEF2 TACC2 SYNE2 SPAG17 DNAH6

4.50e-051951466eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

4.50e-0519514663486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C EPB41L3 TTC3 SLC6A6 SLC24A2 XRN1

4.50e-0519514667796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

4.63e-051961466d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA7A PLEKHG7 ELMO1 ITPR1 PLEKHA2 PARP15

4.76e-051971466da61afba697ec49ca86e062d35a825280da558ac
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-Treg|ICU-SEP / Disease, condition lineage and cell class

PARG LXN LPAR6 SYNE2 TET1 HERC5

4.76e-051971466c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCellsystemic_lupus_erythematosus-treated|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 ACTB ACTG1 SYNE2 XRN1 HERC6

4.90e-0519814668165ff735095c52994fb5057d89be93cc378b7da
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ACTB ACTG1 EPB41L3 FRMD4B TENM4 SYNE2

4.90e-0519814666d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell(4)_B_cells-(4)_B_Hypermutation|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

4.90e-0519814668be724a49b4c911d68c3e82fb75e96722d0eaa03
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYNE1 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

4.90e-051981466ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPEF2 TOGARAM2 RIBC1 TRIM7 SPAG17 DNAH6

4.90e-0519814661847ce8c344c8a3e50f3cbbf758a38aba69f85b0
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ACTB ACTG1 EPB41L3 FRMD4B TENM4 SYNE2

4.90e-0519814667943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ|B_lymphocytes / Location, Cell class and cell subclass

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

4.90e-05198146641e4bc7964a4895dd05bc62f0ef632ce9c89e34f
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SOX6 EPS8L2 CPS1 EPB41L3 SYNE2 CXADR

4.90e-051981466b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DTYMK CKAP5 FBXL5 KIF14 DCTN3 KPNA2

4.90e-051981466c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

PLEKHG7 VPS13C TTC3 SYNE2 SPAG17 AP3D1

5.03e-05199146661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellLeuk-UTI-Lymphocyte-T_NK-T_NK_proliferative|Leuk-UTI / Disease, Lineage and Cell Type

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

5.03e-05199146687113d398585076ece86b9098781e817f8ca241b
ToppCell(4)_Endothelial_cells-(4)_Blood_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CPXM2 ACTG1 ATP8B1 LXN EPB41L3 LPAR6

5.03e-051991466e24d70e79f25cdd3300bf5e2322713355264d4c5
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Cycling_T|lymph-node_spleen / Manually curated celltypes from each tissue

DTYMK ACTB ACTG1 MCM6 RRM1 KIF14

5.03e-05199146628fc342d2d178ce33203a78eb9eedae54fa9c916
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

P4HA2 RBBP4 RRM1 TRABD SYNE2 TOP2B

5.03e-051991466fe3b7d540a644dfc6beea171c809b4d1ba4e188f
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CTNNAL1 SYNE1 MCM6 RRM1 SYNE2 KIF14

5.03e-051991466101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DTYMK ACTB ACTG1 MCM6 RRM1 KPNA2

5.03e-0519914660cae9c80c15542fd86a82d7b6d6a3ad690cee410
ToppCellproximal-Epithelial-Ciliated|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPEF2 TOGARAM2 RIBC1 SPAG17 PZP DNAH6

5.03e-0519914669700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CTNNAL1 SYNE1 MCM6 RRM1 SYNE2 KIF14

5.03e-051991466e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCellMild/Remission-Developping_Plasmablast|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

5.03e-05199146658c772ec763109a4009f52424fbb214fc23d0c09
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SOX6 EPS8L2 VPS13C EPB41L3 SYNE2 CXADR

5.03e-051991466a270630626df614f8605abddb7dee7c4d74f6149
ToppCellproximal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPEF2 TOGARAM2 RIBC1 SPAG17 PZP DNAH6

5.03e-0519914661188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCellCOVID-19_Convalescent-T/NK_proliferative|COVID-19_Convalescent / Disease condition and Cell class

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

5.03e-051991466c608d953b852b67a4e36bd63d45f0deec3eefbd9
ToppCellproximal-Epithelial-Ciliated-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPEF2 TOGARAM2 RIBC1 SPAG17 PZP DNAH6

5.03e-0519914662e8ace105c4e2405baa06d953e52888b54e2d055
ToppCell10x3'2.3-week_12-13-Lymphocytic_B|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

P4HA2 RBBP4 RRM1 TRABD SYNE2 TOP2B

5.03e-051991466cdee798e3586e4e7a15de598239090a85752ea1e
ToppCellMild/Remission-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

5.03e-0519914661dda6116de639140c2d6f5012b7ab9ad0f737ae1
ToppCellnormal_Lymph_Node-T/NK_cells-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

5.03e-051991466cefcfe639a3396bccf2354ca605a1e18b964fbf2
ToppCell(10)_Ciliated|World / shred by cell type by condition

SYNE1 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

5.18e-0520014661b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPEF2 RIBC1 DNAH1 SPAG17 PZP DNAH6

5.18e-05200146631d75c26055177d656df1fbb10b764cebd61e122
ToppCellSevere-Developping_Plasmablast|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

5.18e-0520014666d0cd00e52568d23597cc2a4059bd967d7d2dab5
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-T/NK_proliferative|ICU-NoSEP / Disease, condition lineage and cell class

CTNNAL1 DTYMK MCM6 RRM1 KIF14 KPNA2

5.18e-052001466f70cc9198339eab7fbc68f5d9b75dfb28c9afc89
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

SYNE1 SPEF2 TOGARAM2 SPAG17 DNAH6 WDR49

5.18e-0520014663305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPEF2 RIBC1 DNAH1 SPAG17 PZP DNAH6

5.18e-052001466e1dce91c6c531bb212002a14705e496d77ad3490
Drugplakin

SYNE1 ACTBL2 SPTBN2 ACTB ACTG1 ACTG2 SYNE2

9.37e-07821457CID000018752
DrugNsc687160

ACTBL2 ACTB ACTG1 ACTG2

4.51e-06181454CID005459290
Drugtolytoxin

ACTBL2 ACTB ACTG1 ACTG2

5.68e-06191454CID006440827
DrugNSC312786

ACTBL2 ACTB ACTG1 ACTG2

8.68e-06211454CID000329495
DrugAC1L8NVR

ACTBL2 ACTB ACTG1 ACTG2

8.68e-06211454CID000384633
DrugAC1L1GXW

ACTBL2 ACTB ACTG1 ACTG2 F8 SLC6A6

3.09e-05941456CID000003891
Drugmanidipine

ACTBL2 ACTB ACTG1 ACTG2 PKD1L3 ITPR1

3.28e-05951456CID000004008
Drugazaspiracid

ACTBL2 ACTB ACTG1 ACTG2

3.80e-05301454CID006451158
Drugbistheonellide A

ACTBL2 ACTB ACTG1

4.02e-05111453CID006441172
DrugViroisin

ACTBL2 ACTB ACTG1

4.02e-05111453CID000119538
DrugAC1NSWD2

SYNE1 TOP2B

4.03e-0521452CID005318091
Drugdiethyl acetylenedicarboxylate

SYNE1 SPAG17

4.03e-0521452CID000069803
DrugAC1L1HS4

ACTBL2 ACTB ACTG1 ACTG2

4.94e-05321454CID000004267
Drugberyllium fluoride

ACTBL2 ACTB ACTG1 ACTG2 FANCC SPAG17

5.18e-051031456CID000024589
DrugBFDGE

ACTBL2 ACTB ACTG1

5.34e-05121453CID000091511
DrugAids016406

ACACA FANCC TOP2B

5.34e-05121453CID011979621
DiseaseMoyamoya disease (implicated_via_orthology)

ACTBL2 ACTB ACTG1 ACTG2 POTEKP

1.19e-1081395DOID:13099 (implicated_via_orthology)
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTBL2 ACTB ACTG1 ACTG2 POTEKP

1.19e-1081395DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTBL2 ACTB ACTG1 ACTG2 POTEKP

1.19e-1081395DOID:0081112 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTBL2 ACTB ACTG1 ACTG2 POTEKP

1.19e-1081395DOID:14004 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTBL2 ACTB ACTG1 ACTG2 POTEKP

5.34e-10101395DOID:10486 (implicated_via_orthology)
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTBL2 ACTB ACTG1 ACTG2 POTEKP

5.34e-10101395DOID:13832 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome

ACTB ACTG1

2.20e-0521392cv:C1853623
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

2.20e-0521392C1140716
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

2.20e-0521392C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

2.20e-0521392C1527348
DiseaseIris Coloboma with Ptosis, Hypertelorism, and Mental Retardation

ACTB ACTG1

2.20e-0521392C1855722
DiseaseAnoxia of brain

ITPR1 ITPR2

2.20e-0521392C0995195
DiseaseFryns-Aftimos Syndrome

ACTB ACTG1

2.20e-0521392C1853623
Diseaseserum gamma-glutamyl transferase measurement

TRPM7 ACTG1 ATP8B1 CPS1 ITPR1 TRMT10C TENM4 SYNJ2 SLC24A2 EHF TBC1D12 UGT2B4 STKLD1 BICC1 KPNA2

2.84e-0591413915EFO_0004532
Diseasecholelithiasis

RAPSN ATP8B1 FCHO2 CPS1 SYNJ2

6.18e-05881395EFO_0004799
DiseaseSphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1) measurement

RAPSN SYNE2

1.31e-0441392EFO_0022116
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.31e-0441392cv:CN293514
Diseaselevel of Sphingomyelin (d40:2) in blood serum

RAPSN SYNE2 ANKRD17

1.69e-04231393OBA_2045181
DiseaseMalignant neoplasm of breast

WDR88 SYNE1 YY2 TACC2 ATP8B1 PFKFB4 EPB41L3 TTC3 PIK3R4 SERPINB5 SYNJ2 FKTN UNC45B SYNE2 NLE1

1.72e-04107413915C0006142
Diseaselymphocyte count

TTF2 P4HA2 RAPSN ACACA POTEF KIAA0232 RPS6KA1 SPEF2 ACTB CPS1 RRM1 ELMO1 ITPR1 ITPR2 TENM4 LPAR6 TBC1D14 AP3D1

1.85e-04146413918EFO_0004587
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

2.18e-0451392C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

2.18e-0451392C0410190
Diseasebreast size

VPS13C ELMO1 SPAG17 PZP

3.22e-04691394EFO_0004884
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

3.26e-0461392cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

3.26e-0461392C0410189
Diseasemetabolite measurement

P4HA2 RAPSN MCM6 CPS1 LACTB FBXL5 ITPR2 SYNE2 UGT2B4 FBXO39

3.35e-0456013910EFO_0004725
Diseaseneuropsychological test

PLCXD2 SLC6A6 ZNF20 TENM4 SLC24A2 TARBP1

3.53e-041971396EFO_0003926
Diseaselevel of Sphingomyelin (d36:2) in blood serum

RAPSN ANKRD17

4.56e-0471392OBA_2045177
DiseaseUveoretinal Coloboma

ACTB ACTG1

4.56e-0471392C4554007
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

4.56e-0471392C0751337
Diseasecitrate measurement

RAPSN CPS1 ACOT11 FBXO39

5.39e-04791394EFO_0010114
DiseaseChromosomal Instability

CKAP5 LXN

6.06e-0481392C1257806
Diseaseplatelet measurement

P4HA2 RAPSN KIAA0232 CPS1 ELMO1 TBC1D14 MFN2

7.59e-043151397EFO_0005036
DiseaseTodd Paralysis

TRPM7 UNC45B

7.76e-0491392C0234544
DiseaseParalysed

TRPM7 UNC45B

7.76e-0491392C0522224
DiseaseCongenital ocular coloboma (disorder)

ACTB ACTG1

7.76e-0491392C0009363
DiseaseCongenital neurologic anomalies

ACTB ACTG1

9.67e-04101392C0497552
DiseaseCranioschisis

ACTB ACTG1

9.67e-04101392C0265541
Diseaselevel of Sphingomyelin (d34:0) in blood serum

RAPSN SYNE2

1.18e-03111392OBA_2045176
Diseasehomocysteine measurement

CPS1 GTPBP10 MFN2

1.34e-03461393EFO_0004578
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2

1.41e-03121392DOID:1441 (implicated_via_orthology)
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

1.41e-03121392DOID:11726 (implicated_via_orthology)
Diseasemetabolite measurement, body weight gain

RAPSN TACC2

1.41e-03121392EFO_0004566, EFO_0004725
Diseaselevel of Sphingomyelin (d34:2) in blood serum

RAPSN ANKRD17

1.66e-03131392OBA_2045174
Diseaseskin aging measurement

P4HA2 RAPSN PKD1L3 SLC24A2 SYNE2

1.70e-031811395EFO_0008006
Diseasegallstones

RAPSN ATP8B1 CPS1 SYNJ2

1.73e-031081394EFO_0004210
Diseasefibrinogen measurement

CPS1 PKD1L3 ITPR1 TTC17

1.79e-031091394EFO_0004623
Diseaseresponse to simvastatin, total cholesterol change measurement, response to fenofibrate

COG7 MCM6 BICC1

1.81e-03511393EFO_0007806, GO_1901557, GO_1903491
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

LATS1 BICC1

1.93e-03141392DOID:898 (implicated_via_orthology)
Diseasetrimethylamine-N-oxide measurement

ITPR2 TTC13

1.93e-03141392EFO_0010541
Diseasereceptive language perception, parental genotype effect measurement

MUC19 ACTG2

1.93e-03141392EFO_0005686, EFO_0005939
Diseasephosphatidylcholine 36:3 measurement

RAPSN KIF2B

2.22e-03151392EFO_0010381
Diseasepulse pressure measurement

SOX6 P4HA2 RAPSN TRPM7 CKAP5 PKD1L3 GTPBP10 LACTB PIK3R4 HOXB3 TENM4 TET1 TBC1D12 AP3D1 BICC1

2.41e-03139213915EFO_0005763
DiseaseBlood Platelet Disorders

ACTB AP3D1

2.53e-03161392C0005818
Diseasefibrinogen measurement, factor VII measurement

CPS1 PKD1L3 TTC17

2.61e-03581393EFO_0004619, EFO_0004623
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 FKTN

2.86e-03171392DOID:9884 (is_implicated_in)
DiseaseAdenocarcinoma of lung (disorder)

RRM1 TTF1 LATS1 TAF1L KPNA2

2.98e-032061395C0152013
Diseasehematocrit

SOX6 RAPSN ACACA ATP8B1 ITPR1 ITPR2 FANCC ANKRD17 TTC13 HBE1 AP3D1 BICC1

3.05e-03101113912EFO_0004348
Diseaseborna disease (biomarker_via_orthology)

PARG EIF2A

3.21e-03181392DOID:5154 (biomarker_via_orthology)
Diseasecortical thickness change measurement

FRMD4B MMADHC

3.21e-03181392EFO_0021501
Diseasephosphatidylcholine 36:4 measurement

RAPSN UGT2B4

3.21e-03181392EFO_0010382
Diseasemean platelet volume

RAPSN KIAA0232 PFKFB4 FCHO2 CPS1 ELMO1 SLC6A6 TRABD SYNE2 TBC1D14 TTC13 WDR49

3.28e-03102013912EFO_0004584
Diseasegamma-aminoisobutyric acid measurement

TACC2 AP3D1

3.57e-03191392EFO_0010482
Diseaselevel of Sphingomyelin (d38:2) in blood serum

RAPSN ANKRD17

3.57e-03191392OBA_2045179
Diseaseinferior parietal cortex volume measurement

CPXM2 HBE1

3.57e-03191392EFO_0010307
Diseaseacetate measurement

MCM6 FAM182A

3.96e-03201392EFO_0010112
Diseasemacrophage inflammatory protein 1b measurement

DCAF1 ACACA SNRK UNC45B

3.98e-031361394EFO_0008219
Diseasebipolar I disorder

RAPSN SYNE1 TENM4 WDR49

4.52e-031411394EFO_0009963
Diseaseobsolete_red blood cell distribution width

SOX6 P4HA2 RAPSN KIAA0232 MCM6 FCHO2 CPS1 RRM1 F8 SYNE2 TBC1D14 TBC1D12 STKLD1 HBE1

4.61e-03134713914EFO_0005192
Diseasemitochondrial DNA measurement

ACTG2 RRM1 TRABD KCNK2 MFN2 BICC1

4.71e-033281396EFO_0006312

Protein segments in the cluster

PeptideGeneStartEntry
AIQMQNSTKKWTQVF

TBC1D12

741

O60347
NSTKKWTQVFASVMK

TBC1D12

746

O60347
QCKSKWTEILTKRMT

TTF1

736

Q15361
QLLNKTWKEMRATSE

ELMO1

461

Q92556
KQQLLLISKMDSWNT

COG7

591

P83436
ILASLSTFQQMWISK

ACTBL2

346

Q562R1
LASLSTFQQMWISKQ

POTEKP

346

Q9BYX7
LASLSTFQQMWISKQ

ACTB

346

P60709
LASLSTFQQMWISKQ

ACTG1

346

P63261
TWLVAMNTTTKEKII

FAM78B

171

Q5VT40
QMKAFWKLSSISEKS

FCHO2

731

Q0JRZ9
RQSLIKLWESMSTQA

ACACA

1606

Q13085
NVSSLKMLVAKDNWV

ACOT11

391

Q8WXI4
ILASLSTFQQMWISK

ACTG2

346

P63267
WNSLIKMVSSSTENN

ANKRD17

2566

O75179
KASLMNSWKTTLSVD

CCDC87

581

Q9NVE4
MEETNTQIAWPSKLK

BICC1

81

Q9H694
LSMTIWPSESDKIQK

ATP8B1

1166

O43520
FKLMTSSTNNWVLIK

AP3D1

226

O14617
KVMVSNDSHTWVTVK

CPXM2

226

Q8N436
SATNIVKWIMKQQNA

PZP

1236

P20742
LQVWTKVLEKSSDLM

RAPSN

26

Q13702
KFSKTASMLWLLQQE

NUP107

201

P57740
AVNCNTSWKITLFMK

ITPR2

211

Q14571
TTIMSNKVCNWLVIS

OR6C65

131

A6NJZ3
MQQANKVSLKATWTD

ANKRD53

36

Q8N9V6
LTVTQKTKNDMTVWS

MMADHC

176

Q9H3L0
LASLSTFQQMWISKQ

POTEF

1046

A5A3E0
KSSEHTLAKMWNVVQ

DCAF1

716

Q9Y4B6
TAESIKNQMTVKEWE

MCM6

321

Q14566
DKTFTVQTTWSSMKL

KIF14

1076

Q15058
AETSWQIMANIIKKC

PARP15

176

Q460N3
VLSEKVSQLMEWTNK

MAGT1

36

Q9H0U3
MFTIQKKILVSWSSP

ERVS71-1

221

P61550
SVNCNTSWKIVLFMK

ITPR1

211

Q14643
AEEKAAVTSLWSKMN

HBE1

6

P02100
LETQMKVINWQTSLH

LATS1

956

O95835
TSLMLTETQVKIWFQ

MNX1

276

P50219
SASQLMVKLLVWQKS

FAM182A

106

Q5T1J6
SKSLTMVALAKLWEA

LACTB

166

P83111
DTTINVMKWKTVSTI

KCNK2

51

O95069
SEEQWTKALKFMLTN

BECN1

421

Q14457
KLSTWKVQLGVLQSM

ECPAS

1726

Q5VYK3
MVTSPKLLSWIKNES

PCNX2

1541

A6NKB5
KDIWTKMADTNSVAT

KIAA0232

826

Q92628
ILTLMWDKNNKLSLT

MUC19

581

Q7Z5P9
SLVFKQKTITSWMDT

PARG

71

Q86W56
QKTITSWMDTKGIKT

PARG

76

Q86W56
DLKVWTSQMKRTIQT

PFKFB4

296

Q16877
LQEWLTEVMKSNKGI

FAM151B

86

Q6UXP7
MSWAKLARQATNLKV

FBXO39

271

Q8N4B4
KLTKKEWISSMITTC

HERC6

446

Q8IVU3
LSSLKKLWVMNSQVS

LRRC4

241

Q9HBW1
IVDDTSTQWSKNMKH

F8

1351

P00451
DTIQNSIKMKNWSVR

LPAR6

296

P43657
TKESVTLTWNMINTT

LRIT3

496

Q3SXY7
LSSKEKIWTQEMLLQ

EPS8L2

81

Q9H6S3
SNGKSTVINAMLWDK

MFN2

106

O95140
MSDTWSSIQAHKKQL

METTL3

1

Q86U44
KLMIWDTRSNNTSKP

RBBP4

251

Q09028
ASQLMVKLLVWQKSV

FAM182B

51

Q5T319
SEANMKVWLLKLLSQ

MTERF2

201

Q49AM1
SKIKSWANKMEALTS

P4HA2

56

O15460
TQKDWITNMITTCLK

HERC5

456

Q9UII4
WATLQESTFSKLVQM

HERC5

531

Q9UII4
NPKTNIQKEATWTMS

KPNA2

346

P52292
LASLSTFQQMWISKQ

POTEE

1046

Q6S8J3
KTTMLLSKQFVQWDE

DCTN3

156

O75935
SLIKSIWVMAISQHQ

FRMD4B

341

Q9Y2L6
SQVQMFLKDSWISSL

DNAH1

551

Q9P2D7
LKTQMSSCVAKWLQD

CKAP5

1196

Q14008
MTNQILVEKSVTGWK

CPS1

616

P31327
TWMKGISKKLTEETQ

DNAH6

1911

Q9C0G6
TWMFITKKQTDQTTL

CD101

261

Q93033
RSVVMSTKNKQQVVW

CD101

411

Q93033
KKQLLNLWISDTMSS

GTPBP10

356

A4D1E9
LKKLQMENNGWVSVT

CTNNAL1

711

Q9UBT7
KTEQTEPSIMNTWKD

EHF

131

Q9NZC4
QKLSDSQKMPTSWLA

CXADR

176

P78310
MQKLSVWDQASTLET

FANCC

16

Q00597
TNSTLTKQIFPWMKE

HOXB3

121

P14651
QVAITINSEWTMKAK

CEACAM19

121

Q7Z692
INSEWTMKAKTEVQV

CEACAM19

126

Q7Z692
DSTQWRAVKKFIMLT

FKTN

51

O75072
VSTVQMWLLLKFNQT

CUL9

1771

Q8IWT3
ITSTAWKNKDITMQS

FBXL5

426

Q9UKA1
ADKVTMLWNKKATAV

EIF2A

221

Q9BY44
MLWNKKATAVLVIAS

EIF2A

226

Q9BY44
TSTSQSWVQKMETKT

EPB41L3

816

Q9Y2J2
TATKWVAMIPQKNQT

KIF2B

111

Q8N4N8
VSWKVNSNVMTSNLK

LRRN1

541

Q6UXK5
TSNLKWSSATMKIDN

LRRN1

551

Q6UXK5
TLRNTEVKNAMKQLW

OR4C5

301

Q8NGB2
NSTEDTWYKMVKIQT

LXN

151

Q9BS40
KNKIKLTDMWTASCV

ARHGAP20

126

Q9P2F6
MKDWVEALNQASKIT

PLEKHA2

101

Q9HB19
STLKVWDVKAQKLAM

NLE1

436

Q9NVX2
KLVMDTWQQASLAVS

SPEF2

1251

Q9C093
MRKNKSVWITISSTN

SLC6A6

176

P31641
ILNMSLWSLTKEKVE

TOP2B

1146

Q02880
GAQQWMTKSLTEEKT

PRCC

421

Q92733
TETLTNTLKEVNMRW

SYNE1

7206

Q8NF91
WIKEIKESLMVLNSS

SYNE2

2056

Q8WXH0
NQLKTSMQSVLQEWK

SYNE2

5266

Q8WXH0
IVNASTTNKKMWGEQ

SYNJ2

596

O15056
SSDWQMKEKGLVSIQ

TOGARAM2

501

Q6ZUX3
MDLQQSTTITSLEKW

SLC24A2

1

Q9UI40
VMKGWNILTNSEKSK

NDUFS1

96

P28331
MLQNKKTSSQLSREW

TAF1L

1126

Q8IZX4
KIKWDCSTLSRQVQM

NEXMIF

1111

Q5QGS0
LQMSKKGCVWSIISQ

PKD1L3

1456

Q7Z443
SQWTNPSTMANAKVK

SERPINB5

256

P36952
LASLSTFQQMWISKQ

POTEI

1046

P0CG38
GVQSLNWTKIMKTIV

SUPT16H

896

Q9Y5B9
SVKVQEKSTWKMCIS

SNRK

676

Q9NRH2
IKKTQQRSLMDWSFT

SPAG17

771

Q6Q759
ISKILGSRWKSMSNQ

SOX6

651

P35712
SMTGIEVEKWTQNKK

TET1

701

Q8NFU7
MWTSNLSKVRQSLKN

CCDC54

16

Q8NEL0
FISTGMQSWTKSQKN

CLEC4C

96

Q8WTT0
TVKIWNSQKMEGKTT

PIK3R4

1016

Q99570
ASIATIQMQSRNKKW

TBC1D14

656

Q9P2M4
KKLCLKMTQVTTQWL

UNC45B

836

Q8IWX7
FMWKTDLLTTQQITV

VWDE

1146

Q8N2E2
FSKVAKSWMNLKSIS

TTC13

811

Q8NBP0
MQETFKNLTSVGKTW

ZNF20

36

P17024
TTVSSEMKNKVWNVS

TRIM7

301

Q9C029
VMDVAISNNKKWILS

WDR88

366

Q6ZMY6
QAEKTLDTEWKSQTM

RIBC1

301

Q8N443
GTVKIWNMKTTECSN

SMU1

371

Q2TAY7
QAWMREKTKVIESTQ

SPTBN2

971

O15020
KTVWEISQKTVLKMA

RRM1

681

P23921
MSMKWTSALLLIQLS

UGT2B4

1

P06133
MKKWSVTQNLTFREQ

PLCXD2

91

Q0VAA5
LSSNVLMTDKAKWNI

STKLD1

176

Q8NE28
KNWSTDLNIQEIMTV

TRABD

306

Q9H4I3
LLTSFWKSLQQDTVM

RFX8

196

Q6ZV50
SSSLGTRKWEQKQMQ

YY2

161

O15391
TVSFWMIDTGQKIKQ

WDR49

171

Q8IV35
GKSTMVNTLFKSKVW

SEPTIN12

61

Q8IYM1
VNMKISTDKSWQGVT

XRN1

151

Q8IZH2
QIWSQKTGMTKLKEA

USP29

11

Q9HBJ7
QNTAMLLKELLSWKV

TTC3

836

P53804
TQMKTQEWDNSKSIL

TENM4

2506

Q6N022
LSVSKWNTFLKAMLV

SEMA7A

276

O75326
TSKEMENLWGIKSIN

VPS13C

2231

Q709C8
EEKLAVTNQKWTCMT

TACC2

2471

O95359
KVLEKNQTSWVLSSM

TTC17

1006

Q96AE7
QTENIKKTWMAQITT

PLEKHG7

651

Q6ZR37
DMAWKIISSLSNTQL

TARBP1

971

Q13395
LELDKWKTTMKSSVQ

TRMT10C

61

Q7L0Y3
MSQKSWIESTLTKRE

TRPM7

1

Q96QT4
KSVIVSQWTNMLKVV

TTF2

1011

Q9UNY4
TTLNWKMVDASKSIE

DTYMK

171

P23919
WNTVSETAKDLVSKM

RPS6KA1

641

Q15418