Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR51A7 OR2K2 ADRA2A OR4S2 OR6C3 ADGRG1 OR2M3 TAS2R19 PTGDR LGR5 ADGRG4 PGR OR5AL1	6.87e-05	884	83	13	GO:0004930
GeneOntologyMolecularFunction	ribonuclease A activity	RNASE2 RNASE3	1.69e-04	5	83	2	GO:0004522
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR51A7 OR2K2 ADRA2A CSF1R OR4S2 SCN7A OR6C3 ADGRG1 OR2M3 TAS2R19 PTGDR LGR5 ADGRG4 PGR OR5AL1	4.15e-04	1353	83	15	GO:0004888
GeneOntologyMolecularFunction	receptor ligand activity	IFNB1 NPPC CCL4L1 CMTM2 CCL2 CCL7 IFNA5 TFF1 PNOC	4.42e-04	547	83	9	GO:0048018
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 3'-phosphomonoesters	RNASE2 RNASE3	4.70e-04	8	83	2	GO:0016892
GeneOntologyMolecularFunction	CCR2 chemokine receptor binding	CCL2 CCL7	4.70e-04	8	83	2	GO:0031727
GeneOntologyMolecularFunction	signaling receptor activator activity	IFNB1 NPPC CCL4L1 CMTM2 CCL2 CCL7 IFNA5 TFF1 PNOC	4.84e-04	554	83	9	GO:0030546
GeneOntologyMolecularFunction	cytokine activity	IFNB1 CCL4L1 CMTM2 CCL2 CCL7 IFNA5	6.12e-04	250	83	6	GO:0005125
GeneOntologyMolecularFunction	signaling receptor regulator activity	IFNB1 NPPC CCL4L1 CMTM2 CCL2 CCL7 IFNA5 TFF1 PNOC	1.03e-03	616	83	9	GO:0030545
GeneOntologyMolecularFunction	lipopolysaccharide binding	RNASE2 RNASE3 BPIFC	1.05e-03	48	83	3	GO:0001530
GeneOntologyMolecularFunction	CCR1 chemokine receptor binding	CCL4L1 CCL7	1.10e-03	12	83	2	GO:0031726
GeneOntologyMolecularFunction	chemokine activity	CCL4L1 CCL2 CCL7	1.25e-03	51	83	3	GO:0008009
GeneOntologyMolecularFunction	CCR chemokine receptor binding	CCL4L1 CCL2 CCL7	1.64e-03	56	83	3	GO:0048020
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR51A7 OR2K2 CCL4L1 ADRA2A OR4S2 GUCY2F OR6C3 ADGRG1 CCL2 CCL7 OR2M3 TAS2R19 PTGDR LGR5 ADGRG4 PNOC PGR OR5AL1 ITPR3	1.71e-06	1395	82	19	GO:0007186
GeneOntologyBiologicalProcess	sensory perception	OR51A7 OR2K2 CACNA1F ADRA2A OR4S2 GUCY2F SLC26A5 OR6C3 CCL2 OR2M3 TAS2R19 SLC38A8 PNOC OR5AL1 ITPR3	1.86e-05	1072	82	15	GO:0007600
Domain	SMALL_CYTOKINES_CC	CCL4L1 CCL2 CCL7	2.12e-04	26	84	3	PS00472
Domain	Chemokine_CC_CS	CCL4L1 CCL2 CCL7	2.12e-04	26	84	3	IPR000827
Domain	HEAT_REPEAT	SMG1 HEATR4 UTP20 TANGO6	2.78e-04	70	84	4	PS50077
Domain	RNaseA_AS	RNASE2 RNASE3	5.50e-04	8	84	2	IPR023411
Domain	RNASE_PANCREATIC	RNASE2 RNASE3	5.50e-04	8	84	2	PS00127
Domain	ARM-type_fold	SMG1 HEATR4 UBR4 UTP20 NUP188 UNC79 TANGO6	8.35e-04	339	84	7	IPR016024
Domain	SCY	CCL4L1 CCL2 CCL7	8.88e-04	42	84	3	SM00199
Domain	Chemokine_IL8-like_dom	CCL4L1 CCL2 CCL7	1.02e-03	44	84	3	IPR001811
Domain	IL8	CCL4L1 CCL2 CCL7	1.02e-03	44	84	3	PF00048
Domain	RNAse_Pc	RNASE2 RNASE3	1.07e-03	11	84	2	SM00092
Domain	RNaseA	RNASE2 RNASE3	1.51e-03	13	84	2	PD000535
Domain	RNaseA	RNASE2 RNASE3	2.02e-03	15	84	2	IPR001427
Domain	RNaseA_domain	RNASE2 RNASE3	2.02e-03	15	84	2	IPR023412
Domain	RnaseA	RNASE2 RNASE3	2.02e-03	15	84	2	PF00074
Domain	-	RNASE2 RNASE3	2.02e-03	15	84	2	3.10.130.10
Domain	Channel_four-helix_dom	CACNA1F SCN7A SLC9C2	2.16e-03	57	84	3	IPR027359
Domain	-	CACNA1F SCN7A SLC9C2	2.16e-03	57	84	3	1.20.120.350
Domain	Interferon_alpha/beta/delta	IFNB1 IFNA5	2.60e-03	17	84	2	IPR000471
Domain	Interferon	IFNB1 IFNA5	2.60e-03	17	84	2	PF00143
Domain	IFabd	IFNB1 IFNA5	2.60e-03	17	84	2	SM00076
Domain	INTERFERON_A_B_D	IFNB1 IFNA5	2.60e-03	17	84	2	PS00252
Domain	MARVEL	CMTM2 MARVELD3	6.52e-03	27	84	2	PF01284
Domain	Marvel	CMTM2 MARVELD3	7.00e-03	28	84	2	IPR008253
Domain	MARVEL	CMTM2 MARVELD3	7.00e-03	28	84	2	PS51225
Domain	CYCLINS	CCND3 CCNI	7.00e-03	28	84	2	PS00292
Domain	ARM-like	SMG1 HEATR4 UTP20 RIPOR3 TANGO6	7.43e-03	270	84	5	IPR011989
Domain	Cyclin_N	CCND3 CCNI	9.64e-03	33	84	2	IPR006671
Domain	Cyclin_N	CCND3 CCNI	9.64e-03	33	84	2	PF00134
Pubmed	Signaling lymphocyte activation molecule regulates development of colitis in mice.	CCL4L1 CCL2 CCL7	5.03e-06	14	85	3	22960654
Pubmed	Proteinase-activated receptor-1, CCL2, and CCL7 regulate acute neutrophilic lung inflammation.	CCL2 CCL7	5.90e-06	2	85	2	23972264
Pubmed	Ovarian LGR5 is critical for successful pregnancy.	LGR5 PGR	5.90e-06	2	85	2	24469993
Pubmed	The past as the key to the present: resurrection of ancient proteins from eosinophils.	RNASE2 RNASE3	5.90e-06	2	85	2	11959927
Pubmed	Mouse eosinophil associated ribonucleases: Mechanism of cytotoxic, antibacterial and antiparasitic activities.	RNASE2 RNASE3	5.90e-06	2	85	2	27765572
Pubmed	Characterization of the divergent eosinophil ribonuclease, mEar 6, and its expression in response to Schistosoma mansoni infection in vivo.	RNASE2 RNASE3	5.90e-06	2	85	2	15526002
Pubmed	Eosinophil cationic protein cDNA. Comparison with other toxic cationic proteins and ribonucleases.	RNASE2 RNASE3	5.90e-06	2	85	2	2745977
Pubmed	Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1.	RNASE2 RNASE3	5.90e-06	2	85	2	22677423
Pubmed	Eosinophil-associated ribonuclease 11 is a macrophage chemoattractant.	RNASE2 RNASE3	5.90e-06	2	85	2	25713137
Pubmed	Eosinophil granule proteins in peripheral blood granulocytes.	RNASE2 RNASE3	5.90e-06	2	85	2	1464733
Pubmed	Production and function of monocyte chemoattractant protein-1 and other beta-chemokines in murine glial cells.	CCL2 CCL7	5.90e-06	2	85	2	7642742
Pubmed	Towards the rational design of antimicrobial proteins: single point mutations can switch on bactericidal and agglutinating activities on the RNase A superfamily lineage.	RNASE2 RNASE3	5.90e-06	2	85	2	23992292
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	5.90e-06	2	85	2	31400758
Pubmed	Biochemical and functional similarities between human eosinophil-derived neurotoxin and eosinophil cationic protein: homology with ribonuclease.	RNASE2 RNASE3	5.90e-06	2	85	2	3458170
Pubmed	Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesis.	RNASE2 RNASE3	5.90e-06	2	85	2	11331942
Pubmed	Gene structure and enzymatic activity of mouse eosinophil-associated ribonuclease 2.	RNASE2 RNASE3	5.90e-06	2	85	2	11311552
Pubmed	Genetic polymorphisms of eosinophil-derived neurotoxin and eosinophil cationic protein in tropical pulmonary eosinophilia.	RNASE2 RNASE3	5.90e-06	2	85	2	16014847
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	5.90e-06	2	85	2	37450367
Pubmed	Group-2 innate lymphoid cell-dependent regulation of tissue neutrophil migration by alternatively activated macrophage-secreted Ear11.	RNASE2 RNASE3	5.90e-06	2	85	2	32457448
Pubmed	Structure and chromosome localization of the human eosinophil-derived neurotoxin and eosinophil cationic protein genes: evidence for intronless coding sequences in the ribonuclease gene superfamily.	RNASE2 RNASE3	5.90e-06	2	85	2	2387583
Pubmed	Rapid evolution of the ribonuclease A superfamily: adaptive expansion of independent gene clusters in rats and mice.	RNASE2 RNASE3	5.90e-06	2	85	2	10594173
Pubmed	Chemokines CCL2 and CCL7, but not CCL12, play a significant role in the development of pain-related behavior and opioid-induced analgesia.	CCL2 CCL7	5.90e-06	2	85	2	31003094
Pubmed	Progesterone receptor directly inhibits β-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications.	CSN2 PGR	5.90e-06	2	85	2	21527503
Pubmed	Diminished expression of an antiviral ribonuclease in response to pneumovirus infection in vivo.	RNASE2 RNASE3	5.90e-06	2	85	2	12927308
Pubmed	Two highly homologous ribonuclease genes expressed in mouse eosinophils identify a larger subgroup of the mammalian ribonuclease superfamily.	RNASE2 RNASE3	5.90e-06	2	85	2	8901588
Pubmed	Blood eosinophil cationic protein and eosinophil-derived neurotoxin are associated with different asthma expression and evolution in adults.	RNASE2 RNASE3	5.90e-06	2	85	2	34615736
Pubmed	Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells.	RNASE2 RNASE3	5.90e-06	2	85	2	12855582
Pubmed	The product of a novel growth factor-activated gene, fic, is a biologically active "C-C"-type cytokine.	CCL2 CCL7	5.90e-06	2	85	2	8455595
Pubmed	Eosinophil ribonucleases and their cutaneous lesion-forming activity.	RNASE2 RNASE3	5.90e-06	2	85	2	19717523
Pubmed	Sequence variation at two eosinophil-associated ribonuclease loci in humans.	RNASE2 RNASE3	5.90e-06	2	85	2	11102386
Pubmed	Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+/CX3CR1+ M-MDSCs into the tumor microenvironment in a redundant manner.	CCL2 CCL7	5.90e-06	2	85	2	36685592
Pubmed	Multiple glycosaminoglycan-binding epitopes of monocyte chemoattractant protein-3/CCL7 enable it to function as a non-oligomerizing chemokine.	CCL2 CCL7	5.90e-06	2	85	2	24727473
Pubmed	Comparative mapping between humans and pigs: localization of 58 anchorage markers (TOASTs) by use of porcine somatic cell and radiation hybrid panels.	IFNB1 CSN2 CCL2 PGR	8.88e-06	53	85	4	11130978
Pubmed	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	RNASE2 CCL2 CCL7	9.35e-06	17	85	3	20570966
Pubmed	Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.	CCL4L1 CCL2 CCL7	1.33e-05	19	85	3	10438970
Pubmed	A 2-Mb YAC/BAC-based physical map of the ovum mutant (Om) locus region on mouse chromosome 11.	CCL4L1 CCL2 CCL7	1.56e-05	20	85	3	10995569
Pubmed	A unique anti-CD115 monoclonal antibody which inhibits osteolysis and skews human monocyte differentiation from M2-polarized macrophages toward dendritic cells.	CSF1R CCL2	1.77e-05	3	85	2	23924795
Pubmed	Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal Clues to Broad Binding Specificity.	CCL2 CCL7	1.77e-05	3	85	2	26095031
Pubmed	Impacts of macrophage colony-stimulating factor (M-CSF) on the expression of natriuretic peptide precursor type C (NPPC) and regulation of meiotic resumption.	NPPC CSF1R	1.77e-05	3	85	2	30767584
Pubmed	Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome.	RNASE2 RNASE3	1.77e-05	3	85	2	24005575
Pubmed	Ear2 deletion causes early memory and learning deficits in APP/PS1 mice.	RNASE2 RNASE3	1.77e-05	3	85	2	24966384
Pubmed	Differential Roles of Chemokines CCL2 and CCL7 in Monocytosis and Leukocyte Migration during West Nile Virus Infection.	CCL2 CCL7	1.77e-05	3	85	2	26401006
Pubmed	The human glucocorticoid receptor as an RNA-binding protein: global analysis of glucocorticoid receptor-associated transcripts and identification of a target RNA motif.	CCL2 CCL7	1.77e-05	3	85	2	21148795
Pubmed	Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the ribonuclease A gene family.	RNASE2 RNASE3	1.77e-05	3	85	2	9336452
Pubmed	STAT4 is required for IFN-β-induced MCP-1 mRNA expression in murine mast cells.	IFNB1 CCL2	1.77e-05	3	85	2	21646799
Pubmed	Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection.	CCL2 CCL7	1.77e-05	3	85	2	18453605
Pubmed	Localization of the human eosinophil Charcot-Leyden crystal protein (lysophospholipase) gene (CLC) to chromosome 19 and the human ribonuclease 2 (eosinophil-derived neurotoxin) and ribonuclease 3 (eosinophil cationic protein) genes (RNS2 and RNS3) to chromosome 14.	RNASE2 RNASE3	1.77e-05	3	85	2	1577491
Pubmed	Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene.	RNASE2 RNASE3	1.77e-05	3	85	2	15058383
Pubmed	Synergistic effect of PGD2 via prostanoid DP receptor on TNF-alpha-induced production of MCP-1 and IL-8 in human monocytic THP-1 cells.	CCL2 PTGDR	1.77e-05	3	85	2	17307163
Pubmed	MCP-1-MCP-3-Eotaxin gene cluster influences HIV-1 transmission.	CCL2 CCL7	1.77e-05	3	85	2	14571188
Pubmed	Deficiency in CCR2 increases susceptibility of mice to infection with an intracellular pathogen, Francisella tularensis LVS, but does not impair development of protective immunity.	CCL2 CCL7	1.77e-05	3	85	2	33760886
Pubmed	Structural characterization of a monomeric chemokine: monocyte chemoattractant protein-3.	CCL2 CCL7	1.77e-05	3	85	2	8898111
Pubmed	Monocyte chemoattractant protein-1 (MCP-1), not MCP-3, is the primary chemokine required for monocyte recruitment in mouse peritonitis induced with thioglycollate or zymosan A.	CCL2 CCL7	1.77e-05	3	85	2	19641140
Pubmed	Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC.	CCL2 CCL7	1.77e-05	3	85	2	8662823
Pubmed	Eosinophil cationic protein enhances stabilization of β-catenin during cardiomyocyte differentiation in P19CL6 embryonal carcinoma cells.	RNASE2 RNASE3	1.77e-05	3	85	2	23271121
Pubmed	IFNβ autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages.	IFNB1 CCL2	1.77e-05	3	85	2	23542035
Pubmed	IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: a distinct control of the response induced by different IL-2 concentrations.	CCL4L1 CCL2 CCL7	2.10e-05	22	85	3	9177770
Pubmed	Cloning, expression, and chromosomal mapping of a novel human CC-chemokine receptor (CCR10) that displays high-affinity binding for MCP-1 and MCP-3.	CCL2 CCL7	3.53e-05	4	85	2	9364936
Pubmed	HIV-1 Tat protein mimicry of chemokines.	CCL2 CCL7	3.53e-05	4	85	2	9789057
Pubmed	Nucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway.	CCL2 CCL7	3.53e-05	4	85	2	38316963
Pubmed	TLR3 increases disease morbidity and mortality from vaccinia infection.	IFNB1 CCL2	3.53e-05	4	85	2	18097050
Pubmed	Control of regional decidualization in implantation: Role of FoxM1 downstream of Hoxa10 and cyclin D3.	CCND3 PGR	3.53e-05	4	85	2	26350477
Pubmed	Cross talk between progesterone receptors and retinoic acid receptors in regulation of cytokeratin 5-positive breast cancer cells.	RARG PGR	3.53e-05	4	85	2	28692043
Pubmed	The CCL2/CCL7/CCL12/CCR2 pathway is substantially and persistently upregulated in mice after traumatic brain injury, and CCL2 modulates the complement system in microglia.	CCL2 CCL7	3.53e-05	4	85	2	33160071
Pubmed	Intelectin is required for IL-13-induced monocyte chemotactic protein-1 and -3 expression in lung epithelial cells and promotes allergic airway inflammation.	CCL2 CCL7	3.53e-05	4	85	2	19965981
Pubmed	Toll-like receptor 3 activation induces antiviral immune responses in mouse sertoli cells.	IFNB1 CCL2	3.53e-05	4	85	2	18596219
Pubmed	Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice.	CCL2 CCL7	3.53e-05	4	85	2	23033370
Pubmed	Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events.	CCL2 CCL7	3.53e-05	4	85	2	18469140
Pubmed	CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice.	CCL2 CCL7	3.53e-05	4	85	2	20234092
Pubmed	Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells.	CSN2 PGR	3.53e-05	4	85	2	16973758
Pubmed	The role of CCL2, CCL7, ICAM-1, and VCAM-1 in interaction of endothelial cells and natural killer cells.	CCL2 CCL7	3.53e-05	4	85	2	36274485
Pubmed	The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.	CCL2 CCL7	3.53e-05	4	85	2	19587014
Pubmed	Expression levels of eosinophil granule protein mRNAs in induced sputum reflect airway hyperresponsiveness and airflow limitation.	RNASE2 RNASE3	3.53e-05	4	85	2	24814827
Pubmed	Chemokine expression by small sputum macrophages in COPD.	CCL2 CCL7	3.53e-05	4	85	2	21327296
Pubmed	Transcriptional regulation of human eosinophil RNases by an evolutionary- conserved sequence motif in primate genome.	RNASE2 RNASE3	3.53e-05	4	85	2	17927842
Pubmed	Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle.	CCL2 CCL7	3.53e-05	4	85	2	10770925
Pubmed	Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites.	CCL2 CCL7	3.53e-05	4	85	2	17364026
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	CCND3 MSH6 CSF1R BARD1 APOA2 TFF1 PGR	3.78e-05	374	85	7	19625176
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	CCND3 MSH6 CSF1R BARD1 APOA2 TFF1 PGR	4.25e-05	381	85	7	18676680
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	CCND3 MSH6 CSF1R BARD1 APOA2 TFF1 PGR	4.32e-05	382	85	7	19170196
Pubmed	Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis.	IFNB1 CCL2 IFNA5	4.42e-05	28	85	3	15481145
Pubmed	Variation in genes encoding eosinophil granule proteins in atopic dermatitis patients from Germany.	RNASE2 RNASE3	5.87e-05	5	85	2	19014520
Pubmed	The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions.	CCL2 CCL7	5.87e-05	5	85	2	27044744
Pubmed	FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.	FBXW10B FBXW10	5.87e-05	5	85	2	37277019
Pubmed	Identification of new regulatory sequences far upstream of the mouse monocyte chemoattractant protein-1 gene.	CCL2 CCL7	5.87e-05	5	85	2	11735217
Pubmed	Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression.	CCL2 CCL7	5.87e-05	5	85	2	28951461
Pubmed	Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.	CCL2 CCL7	5.87e-05	5	85	2	33300045
Pubmed	Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo.	SLC26A5 LGR5	5.87e-05	5	85	2	24496619
Pubmed	Cloning, expression, and characterization of the human eosinophil eotaxin receptor.	CCL2 CCL7	5.87e-05	5	85	2	8642344
Pubmed	In pursuit of leucine-rich repeat-containing G protein-coupled receptor-5 regulation and function in the uterus.	LGR5 PGR	5.87e-05	5	85	2	19797400
Pubmed	Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx.	CCL2 CCL7	5.87e-05	5	85	2	18660381
Pubmed	Atypical E2F repressors and activators coordinate placental development.	CSF1R BARD1 CDC6	7.29e-05	33	85	3	22516201
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	CCND3 MSH6 CSF1R BARD1 APOA2 TFF1 PGR	7.94e-05	421	85	7	19692168
Pubmed	Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1.	MSH6 BARD1	8.80e-05	6	85	2	11498787
Pubmed	CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines.	CCL2 CCL7	8.80e-05	6	85	2	10734104
Pubmed	Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3.	CCL2 CCL7	8.80e-05	6	85	2	7545673
Pubmed	Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment.	CCL2 CCL7	8.80e-05	6	85	2	20107187
Pubmed	Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1.	CCL2 CCL7	8.80e-05	6	85	2	8996246
Pubmed	Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways.	CCL2 CCL7	8.80e-05	6	85	2	10072545
Pubmed	Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta.	TFF1 PGR	8.80e-05	6	85	2	15694343
Cytoband	14q24-q31	RNASE2 RNASE3	3.39e-06	2	85	2	14q24-q31
Cytoband	17q11.2-q12	CCL2 CCL7	7.07e-05	7	85	2	17q11.2-q12
Cytoband	Xq22	COL4A6 GUCY2F	7.64e-04	22	85	2	Xq22
GeneFamily	Adhesion G protein-coupled receptors, subfamily G	ADGRG1 ADGRG4	2.18e-04	7	59	2	917
GeneFamily	Chemokine ligands\|Endogenous ligands	CCL4L1 CCL2 CCL7	4.25e-04	45	59	3	483
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10	5.65e-04	11	59	2	559
GeneFamily	Ribonuclease A family	RNASE2 RNASE3	7.98e-04	13	59	2	723
GeneFamily	Solute carriers	SLC7A4 SLC39A12 SLC34A1 SLC26A5 SLC9C2 SLC38A8	1.78e-03	395	59	6	752
GeneFamily	Cyclins	CCND3 CCNI	3.75e-03	28	59	2	473
GeneFamily	Interferons	IFNB1 IFNA5	4.88e-03	32	59	2	598
GeneFamily	Endogenous ligands	NPPC CCL2 CCL7 PNOC	7.46e-03	237	59	4	542
Coexpression	BURTON_ADIPOGENESIS_PEAK_AT_16HR	MSH6 RNASE2 RNASE3 CDC6	1.10e-05	43	84	4	MM1208
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 CCL7 PTGDR FGFBP1	5.49e-08	107	84	6	7dda60d30c12d9ee15cda5fcbc75c317ca2d026f
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 CCL7 PTGDR FGFBP1	5.49e-08	107	84	6	5356499561a62a80ecd7d9a260aea87bc70543fd
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 CCL7 PTGDR FGFBP1	5.49e-08	107	84	6	8bdfb603ee0e8ca667847be016a9ee5f4f1712f8
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 APOA2 CDC6 PTGDR FGFBP1	2.09e-07	134	84	6	d29ac8152dc581c0da2430d06cd259ac0eded808
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 APOA2 CDC6 PTGDR FGFBP1	2.09e-07	134	84	6	459c39df15d3cf9144ce7827e8d14830d31353bb
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 APOA2 CDC6 PTGDR FGFBP1	2.09e-07	134	84	6	d065449ca3679e4818b74fb7302cc7f1ce62f691
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 APOA2 CDC6 PTGDR FGFBP1	2.09e-07	134	84	6	0be389f416818a22e80098dd809fdf45b14171e8
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KNTC1 CACNA1F CSF1R CCL2 CCL7 CDC6	5.74e-07	159	84	6	c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCell	critical-Epithelial-Secretory-diff\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RNASE2 CSF1R CMTM2 CCL2 CCL7 TFF1	1.88e-06	195	84	6	7889818d0f8b8e5c966fbff74b95a28e3fbcc4d2
ToppCell	Striatum-Endothelial-ENDOTHELIAL_TIP\|Striatum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR TFF1 FGFBP1	2.02e-06	109	84	5	a84a4a3ac19692e5595b9820d49e12ae336f4bbf
ToppCell	Striatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Striatum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR TFF1 FGFBP1	2.02e-06	109	84	5	f7d7b67f7585f2ae0ac905bcf3980264cf9234b8
ToppCell	Striatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Striatum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR TFF1 FGFBP1	2.02e-06	109	84	5	f007fa3dc92d6c8543585e47ccec218263b3266e
ToppCell	Striatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Striatum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR TFF1 FGFBP1	2.02e-06	109	84	5	f4b9fe5335cabe48a5fae7ec51bab0d7bdb17321
ToppCell	Striatum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Striatum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR TFF1 FGFBP1	2.02e-06	109	84	5	8460683529759585bd363d10a16ee13af2bd4e28
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Dcn-Endothelial_Tip.Dcn.Nenf_(Nenf)\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 PTGDR FGFBP1	2.52e-06	114	84	5	7be16e7f7b9c9dbd68933ace3b7f8f661bed41a7
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Dcn\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 PTGDR FGFBP1	2.52e-06	114	84	5	f4bdfc47418d22a49e0c4a6c3bd0663e15fb53bb
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RIPOR3 CCL7 PTGDR FGFBP1 ITPR3	5.76e-06	135	84	5	7e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RIPOR3 CCL7 PTGDR FGFBP1 ITPR3	5.76e-06	135	84	5	4cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RIPOR3 CCL7 PTGDR FGFBP1 ITPR3	5.76e-06	135	84	5	6bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RIPOR3 CCL7 PTGDR FGFBP1 ITPR3	5.76e-06	135	84	5	97989546826bf3739e1b86a10832a457fd37c5d2
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 CDC6 PTGDR FGFBP1	9.31e-06	149	84	5	3980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 PTGDR FGFBP1	1.06e-05	153	84	5	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 PTGDR FGFBP1	1.06e-05	153	84	5	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 PTGDR FGFBP1	1.06e-05	153	84	5	2513edfae62a44e51d3556675a096723194c966c
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 PTGDR FGFBP1	1.53e-05	165	84	5	570483b43ccb5831feec9337b4664814431d40b1
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 PTGDR FGFBP1	1.53e-05	165	84	5	2026a9a07f4d314cc05c167e491312b373468e46
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 CCL7 PTGDR FGFBP1	1.66e-05	168	84	5	26aa96b2b547d11941cb803995ea3d302ee0518c
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l12-45\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IFNB1 SLC39A12 CSF1R CCL2 CCL7	1.76e-05	170	84	5	e028e22ad051c2628248b212b5d28b891e0ee782
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ANO2 GUCY2F NEB UNC79	2.57e-05	184	84	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ANO2 GUCY2F NEB UNC79	2.57e-05	184	84	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ANO2 GUCY2F NEB UNC79	2.57e-05	184	84	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RNASE2 RNASE3 CSF1R CCL2 CCL7	2.71e-05	186	84	5	0859737021747518731aa67fe181d4ca4fdc0721
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCL4L1 RNASE2 CSF1R CCL2 CCL7	2.78e-05	187	84	5	d56664da336a580e9da2ea52622b5ce36fdafb1c
ToppCell	NS-critical-d_16-33-Myeloid-Non-resident_Macrophage\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCL4L1 RNASE2 CSF1R CCL2 CCL7	3.00e-05	190	84	5	4fe9654a9b449ef49ca10b973ac4378dab34cb53
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Monocytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCL4L1 RNASE2 RNASE3 CSF1R CCL7	3.40e-05	195	84	5	aa3914e277918299dc7d2995c0c72288462ad43d
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCL4L1 RNASE2 RNASE3 CSF1R CCL2	3.57e-05	197	84	5	0a22686d586c0334a2fd872a28e26b75693234cf
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL4A6 GUCY2F RIPOR3 FGFBP1	4.34e-05	103	84	4	39d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL4A6 GUCY2F RIPOR3 FGFBP1	4.34e-05	103	84	4	01a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	83f3540683b3b175b10af059ab8898c46eaccc13
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	6d5075d659dac7b96e6857f8485a7d2c4105d685
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	fd0001a0f3a0a4421f96fd21813c21cf6f01d40e
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	3d507f829882d043f633db2612b76936e2042445
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	f20424f9baf3c4059cd6b701761e7595400fc47c
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	9.51e-05	126	84	4	2de551d7a8765afec1da8852727c79fec90f45f8
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 CDC6 FGFBP1	1.14e-04	132	84	4	560e836764ed7806fb18282dfebe434d30112a9a
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL4A6 CCL2 RIPOR3 FGFBP1	1.14e-04	132	84	4	893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2-Inhibitory_Neuron.Gad1Gad2.Gad2-Kcnc3_(GABAergic,_K/Na_Channel_State)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	BPIFC HEATR4 SUN5	1.37e-04	53	84	3	a58b0b1c9991cfebf20e206a129b79f494785138
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2-Inhibitory_Neuron.Gad1Gad2.Gad2-Kcnc3_(GABAergic,_K/Na_Channel_State)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	BPIFC HEATR4 SUN5	1.37e-04	53	84	3	e90685a7c6ef223783b1c1a6b1896fd566449422
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	BPIFC HEATR4 SUN5	1.37e-04	53	84	3	5ad1a5c5c9a1dc66dd7e6de6edbee0176678966c
ToppCell	Control-Fibroblasts-Mesothelial_FB\|Control / group, cell type (main and fine annotations)	NPPC ADRA2A B4GALNT4 LGR5	1.39e-04	139	84	4	e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL4A6 RIPOR3 CCL7 FGFBP1	1.51e-04	142	84	4	f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCell	ASK454-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	RARG UBR4 BARD1 UTP20	1.59e-04	144	84	4	8e693b50bd6c69ce68f44ca6e51f6d0c7f80d82c
ToppCell	Healthy-B_cell\|World / disease group, cell group and cell class	SPATC1 DIP2C ADGRG1 NEB	1.68e-04	146	84	4	588359d3df6ad7090b7fa6c7f8d29cc1717e7f4f
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE2 RNASE3 CCL2 CCL7	2.01e-04	153	84	4	5fbb90b8477f9fdabf3be19efd3068fbf70abee6
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RNASE2 RNASE3 CCL2 CCL7	2.01e-04	153	84	4	2c46183481e6d5a7fa190a743062509465f88e56
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNASE2 RNASE3 CCL2 CCL7	2.01e-04	153	84	4	decc4f3098a9374a6b65c015a9d36380986290bf
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNASE2 RNASE3 CCL2 CCL7	2.01e-04	153	84	4	36a28805c0545c2f410c74a6ca0a70d840e75715
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_4\|367C / Donor, Lineage, Cell class and subclass (all cells)	RNASE2 CSF1R CCL2 TAS2R19	2.01e-04	153	84	4	3570dd844d6479425bf6f62129f88efa45553775
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	COL4A6 RIPOR3 PTGDR FGFBP1	2.06e-04	154	84	4	65dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSF1R BPIFC CCL2 CCL7	2.11e-04	155	84	4	93bfcf5c12cbb61a1e0444312afd2aa411a8bf50
ToppCell	droplet-Bladder-Unstain-18m-Hematologic-leukocyte\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFNB1 CSF1R CCL2 CCL7	2.33e-04	159	84	4	89b5e895e95cdd654edd471bde9b6887939b3503
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	FBXW10B NUP188 CDC6 ITPR3	2.33e-04	159	84	4	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	droplet-Bladder-Unstain-18m-Hematologic\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFNB1 CSF1R CCL2 CCL7	2.33e-04	159	84	4	a80b4637a74bcc6f213d584aba2c727a983eedb3
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSF1R CCL2 CCL7 CDC6	2.44e-04	161	84	4	8937f6b92cb2a93ea8c4780d9200a518c3112e53
ToppCell	Mild_COVID-19-Myeloid-MoAM2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	RNASE2 RNASE3 CCL2 CCL7	2.50e-04	162	84	4	e5fc80ab19d513af6a7e677a5e67bfebca2e963b
ToppCell	TCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS-5\|TCGA-Testes / Sample_Type by Project: Shred V9	CMTR1 TMEM60 MAGEC3 INTS8	2.56e-04	163	84	4	80bc3732afd8501938753120b8403098c7c5e928
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	COL4A6 SLC7A4 RNASE3 CMTM2	2.56e-04	163	84	4	f21951e63188eb0c04675a8f81a0da495c26c007
ToppCell	TCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS\|TCGA-Testes / Sample_Type by Project: Shred V9	CMTR1 TMEM60 MAGEC3 INTS8	2.56e-04	163	84	4	67551fefe22bd5b8178fa248fed2a6c17b19fb0f
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCL4L1 RARG CMTM2 NEB	2.56e-04	163	84	4	4be3158f2a0ab460cfea8080a7370922910b5da9
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 RNASE2 RNASE3 CSF1R	2.62e-04	164	84	4	ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell	droplet-Liver-LIVER-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F CSF1R CCL2 CCL7	2.62e-04	164	84	4	939d4e3911fce185b986639c815de0a0389f6cfd
ToppCell	droplet-Liver-LIVER-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F CSF1R CCL2 CCL7	2.62e-04	164	84	4	3281f2452cc6b11f3e030a3942002b9457dde6fe
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F CSF1R CCL2 CCL7	2.74e-04	166	84	4	03a47b8687f54955e84df1edcb230db332c4ca8f
ToppCell	facs-BAT-Fat-24m-Myeloid\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMTM2 APOA2 NEB TFF1	2.74e-04	166	84	4	001a31aaa4ab4d5606b894faf6fcaad524405064
ToppCell	ICU-SEP-Lymphocyte-B-Plasmablast\|ICU-SEP / Disease, Lineage and Cell Type	NPPC SSPN CDC6 PNOC	2.74e-04	166	84	4	98ce43e14133418f676f1c88c001add9e28259a7
ToppCell	facs-BAT-Fat-24m-Myeloid-myeloid_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMTM2 APOA2 NEB TFF1	2.74e-04	166	84	4	31ed1290b4a977eabfc29674a5c593985bff6a74
ToppCell	facs-BAT-Fat-24m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CMTM2 APOA2 NEB TFF1	2.74e-04	166	84	4	c71ad3fc6a14507609d17756431d3deff9fda418
ToppCell	droplet-Liver-LIVER\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F CSF1R CCL2 CCL7	2.80e-04	167	84	4	90125bfdc34b0f9a471cefe6e8a637d5e5e00790
ToppCell	droplet-Liver-LIVER-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F CSF1R CCL2 CCL7	2.80e-04	167	84	4	4bbc59cc50a68b957125fb11a3b308fe1d542ce9
ToppCell	droplet-Liver-LIVER-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F CSF1R CCL2 CCL7	2.80e-04	167	84	4	a038c522e4783cb62802f613d00bd5f3e3797199
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F CSF1R CCL2 CCL7	2.87e-04	168	84	4	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Resp18_(Bed_nucleus_of_the_stria_terminalis_(BNST))-\|Striatum / BrainAtlas - Mouse McCarroll V32	BPIFC SUN5 C3orf20	2.88e-04	68	84	3	ea33633d93a3a7f82c9abf11472fcfb55b0c4878
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Resp18_(Bed_nucleus_of_the_stria_terminalis_(BNST))--\|Striatum / BrainAtlas - Mouse McCarroll V32	BPIFC SUN5 C3orf20	2.88e-04	68	84	3	5058dcaf02cc893cfd16032e0034dd9fa097c0b8
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Resp18_(Bed_nucleus_of_the_stria_terminalis_(BNST))\|Striatum / BrainAtlas - Mouse McCarroll V32	BPIFC SUN5 C3orf20	2.88e-04	68	84	3	41a697c4628acc8a0f5df2f463c1fdc6ee9b7942
ToppCell	facs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPPC SLC34A1 LGR5 FGFBP1	2.93e-04	169	84	4	daed9083ee05c220365200328c2c50047fe21efd
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1F CSF1R CCL2 CCL7	2.93e-04	169	84	4	a1efc20e34a81ae32f8d278a5486811ade03ef24
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCND3 CCL4L1 ADGRG1 PTGDR	2.93e-04	169	84	4	a3234904d7ff8f451ca894e93badd61d75e3cd2a
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 FBXW10 NUP188 DCUN1D4	3.00e-04	170	84	4	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN7A SUN5 PTGDR PNOC	3.00e-04	170	84	4	667443062882642211ad116043775ef8eda38859
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL4A6 RIPOR3 PTGDR FGFBP1	3.07e-04	171	84	4	2e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL4A6 RIPOR3 PTGDR FGFBP1	3.07e-04	171	84	4	e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCell	11.5-Airway-Epithelial-Basal_cell\|Airway / Age, Tissue, Lineage and Cell class	NUDT18 NPPC ADGRG1 LGR5	3.14e-04	172	84	4	9d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RARG SCN7A ADGRG1 PTGDR	3.14e-04	172	84	4	a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA2A B4GALNT4 NEB TFF1	3.21e-04	173	84	4	82fa5ff6a00216a21a37fafeaf3e21e964c61d47
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA2A B4GALNT4 NEB TFF1	3.21e-04	173	84	4	13f67f61edb734ff846da92d41e81ec4670a2b66
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPPC CCL2 CCL7 UNC79	3.21e-04	173	84	4	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPPC CCL2 CCL7 UNC79	3.21e-04	173	84	4	649b08a409095592cccf31883be69c754411280d
Drug	He-O	MSH6 RNASE3 CSF1R TFF1 PGR	1.02e-06	49	84	5	CID006323367
Drug	poly rI:rC	IFNB1 CCL2 CCL7 IFNA5	4.39e-06	30	84	4	CID011979660
Drug	Ethionamide [536-33-4]; Up 200; 24uM; HL60; HT_HG-U133A	NUDT18 SSPN RNASE3 GUCY2F NUP188 FGFBP1 ITPR3	8.70e-06	198	84	7	2495_UP
Drug	isobavachin	TFF1 PGR	1.35e-05	2	84	2	ctd:C468753
Drug	desmethylicaritin	TFF1 PGR	1.35e-05	2	84	2	ctd:C499404
Disease	Malignant neoplasm of breast	IFNB1 MSH6 SLC39A12 RARG CSF1R GUCY2F UBR4 BARD1 DIP2C UTP20 DTX3L PGR	5.14e-05	1074	84	12	C0006142
Disease	crescentic glomerulonephritis (implicated_via_orthology)	CSF1R CCL2	1.19e-04	6	84	2	DOID:13139 (implicated_via_orthology)
Disease	eosinophil cationic protein measurement	RNASE2 RNASE3	2.22e-04	8	84	2	EFO_0010913
Disease	asparaginase-induced acute pancreatitis	NEB C3orf20	2.85e-04	9	84	2	EFO_1001507
Disease	Cardiotoxicity	RARG CCL2	6.12e-04	13	84	2	C0876994
Disease	Endometrial Neoplasms	MSH6 CCL2 PGR	6.13e-04	58	84	3	C0014170
Disease	anti-basement membrane glomerulonephritis (implicated_via_orthology)	CSF1R CCL2	7.13e-04	14	84	2	DOID:4780 (implicated_via_orthology)
Disease	sclerosing cholangitis	TGFBRAP1 CLEC16A TANGO6	8.95e-04	66	84	3	EFO_0004268
Disease	Endometrial Carcinoma	MSH6 CCL2 PGR	1.15e-03	72	84	3	C0476089
Disease	multiple sclerosis (is_implicated_in)	CCL2 CCL7 CLEC16A	1.20e-03	73	84	3	DOID:2377 (is_implicated_in)
Disease	toxic shock syndrome (is_marker_for)	NPPC CCL2	1.33e-03	19	84	2	DOID:14115 (is_marker_for)
Disease	Nephritis, Tubulointerstitial	CCL2 CCL7	1.62e-03	21	84	2	C0041349
Disease	Nephritis, Interstitial	CCL2 CCL7	2.12e-03	24	84	2	C0027707
Disease	Ureteral obstruction	NPPC CCL2	2.12e-03	24	84	2	C0041956
Disease	breast cancer (implicated_via_orthology)	MSH6 BARD1	2.30e-03	25	84	2	DOID:1612 (implicated_via_orthology)
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	MSH6 BARD1	2.49e-03	26	84	2	C0009405
Disease	Bone Diseases, Developmental	NPPC SLC34A1	2.68e-03	27	84	2	C0005941
Disease	Hereditary non-polyposis colorectal cancer syndrome	MSH6 BARD1	2.68e-03	27	84	2	C1112155

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLDINTAKCMLGLLL	DCUN1D4	211	Q92564
MLINKLWLLLVTLCL	COL4A6	1	Q14031
MKLLAATVLLLTICS	APOA2	1	P02652
KAQLQLLGAVCMLLA	CCND3	96	P30281
LDSMIQLCSKLRNLL	BARD1	101	Q99728
PAKILINLCTALLML	ADGRG4	2776	Q8IZF6
INLCTALLMLNLVFL	ADGRG4	2781	Q8IZF6
YTLLLLQMCNPKLLL	FBXW10	136	Q5XX13
MKICSLTLLSFLLLA	FGFBP1	1	Q14512
LTKQLLHCMACNQLL	CCNI	181	Q14094
LSIVLNICLMLKLSY	SLC7A4	551	O43246
ELCIQLSIIMLGKQL	ANO2	676	Q9NQ90
MHLSQLLACALLLTL	NPPC	1	P23582
KMCFLNKLLLLAVLG	CDAN1	736	Q8IWY9
MLIRQLLAKCGLVLS	RBM25	101	P49756
LMALLVLATVLCNLG	PTGDR	206	Q13258
TLLKAACLDILMLRI	RARG	261	P13631
PVLNMLLNELLCISK	INTS8	106	Q75QN2
LCIKVLRTLQQMLLK	ITPR3	1661	Q14573
YTLLLLQMCNPKLLL	FBXW10B	136	O95170
KVLLCLFTVEMLLKL	CACNA1F	566	O60840
NCLLILILSMIFIKG	MAGEC3	546	Q8TD91
KMAVLRLLQECLTLH	NUDT18	231	Q6ZVK8
VEMLLEKLQLCFLSQ	FSIP2	2921	Q5CZC0
LLLSQLSLMDLMLIC	OR2M3	61	Q8NG83
LLAIMGNCTILFIIK	OR51A7	36	Q8NH64
ILLGNLLIMLTVCLS	OR4S2	36	Q8NH73
LLIMLTVCLSNLFKS	OR4S2	41	Q8NH73
MVPKLFTSQICLLLL	RNASE3	1	P12724
VLLMALVVLNCKSIC	IFNA5	6	P01569
KLLFLTCQKLCQMLA	KNTC1	1101	P50748
LKKCLIDQELLSMAN	MSH6	691	P52701
MKVLLCDLLLLSLFS	PNOC	1	Q13519
LLCTCLILLVKMLNS	SLC34A1	361	Q06495
EEFLCMKVLLLLNTI	PGR	816	P06401
MLVLNCSTKLLILEK	GLYATL3	1	Q5SZD4
ACMSIMALLLLLLLL	CSF1R	521	P07333
ILKNLNEMLCPIIAS	BPIFC	191	Q8NFQ6
MKLCVTVLSLLVLVA	CCL4L1	1	Q8NHW4
CQLMREVLLLKSLGK	DTX3L	446	Q8TDB6
MKVSAALLCLLLIAA	CCL2	1	P13500
LLARISKLLMICQNA	C3orf20	21	Q8ND61
MVCLTLLIALLSING	GUCY2F	471	P51841
LQIRDKMVLECLLNL	HEATR4	756	Q86WZ0
MTNKCLLQIALLLCF	IFNB1	1	P01574
MKVLILACLVALALA	CSN2	1	P05814
LSLVAALMLAKCLQL	DPY19L4	321	Q7Z388
SACLMTTQLICKLLR	DIP2C	1081	Q9Y2E4
MCELKRDLQLLSQFL	ADGRG1	176	Q9Y653
QKILVCSLMLLIRQL	CDC6	461	Q99741
CSLMLLIRQLKIKEV	CDC6	466	Q99741
CQMLEVLLNLLILAC	MARVELD3	201	Q96A59
MKASAALLCLLLTAA	CCL7	1	P80098
ALGILSLILNIMCAA	SEC22C	186	Q9BRL7
NRKCKAISLLAIMIL	SLC39A12	531	Q504Y0
QEILSKQLLLCQFLM	CMTR1	376	Q8N1G2
KQLLLCQFLMALSIV	CMTR1	381	Q8N1G2
LKVIILLCALLALTM	LGR5	681	O75473
LAVLKLACTSSLLMN	OR2K2	181	Q8NGT1
QSKLVLLLCQTVAIM	TAS2R19	256	P59542
LPKILQILLCMTATV	UTP20	1116	O75691
CLMSIIKKLAALNVT	UTP20	1496	O75691
QLAGCLASLMILLVI	SLC26A5	411	P58743
KELMLLIIAGFNTLC	OR5AL1	211	P0C617
KLILGEMTCALNNLL	SMG1	566	Q96Q15
QMLSCLKTSLNILAI	PRAMEF20	286	Q5VT98
FKLFLLIQMILNLVC	SSPN	191	Q14714
MKLSVCLLLVTLALC	SCGB1D2	1	O95969
GKLCEACFLLNLLMI	SLC38A8	101	A6NNN8
SIMNRKLCTLLVLCA	OR6C3	131	Q9NZP0
MVPKLFTSQICLLLL	RNASE2	1	P10153
NKVICALVLVSMLAL	TFF1	6	P04155
KQMKLLLLLLLLSCA	B4GALNT4	11	Q76KP1
QVTLTLVCLAGLLML	ADRA2A	46	P08913
KIRSLGCLIAAMILL	CMTM2	91	Q8TAZ6
TLELSCLLLKQQVLM	CLEC16A	561	Q2KHT3
LLVLCDNSISLVNML	TGFBRAP1	91	Q8WUH2
LLCQKLMEKTGILLL	SUN5	96	Q8TC36
LIAMLLKLAFCLALC	TMEM60	81	Q9H2L4
LLMVHLQVCKALLQK	RIPOR3	621	Q96MK2
MLADALLLLSCLSQL	SPATC1	566	Q76KD6
SQTLLLLLCLKETMI	TANGO6	96	Q9C0B7
LLLCLKETMIRLAAN	TANGO6	101	Q9C0B7
NCLRLGSMKCTLLLI	NUP188	1151	Q5SRE5
LVLLLSLCVVTSLMK	PIGN	626	O95427
LIELCLANVAGMALL	SCN7A	581	Q01118
KLDLCVLSLPRQMIL	SLC9C2	431	Q5TAH2
SSLLRLALLALKVCM	TTC37	1441	Q6PGP7
LALLALKVCMANISN	TTC37	1446	Q6PGP7
NITLMCLRILQKLIK	UBR4	4011	Q5T4S7
LTLDQMIRILLCLKN	TRMT10C	351	Q7L0Y3
ILFNMLNCLKILCLH	UNC79	971	Q9P2D8
MLSILLAKKCQTLVT	NEB	3821	P20929