Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein decrotonylase activity	HDAC3 HDAC8 HDAC1	6.39e-07	5	81	3	GO:0160008
GeneOntologyMolecularFunction	histone decrotonylase activity	HDAC3 HDAC8 HDAC1	6.39e-07	5	81	3	GO:0160009
GeneOntologyMolecularFunction	histone deacetylase activity	HDAC3 HDAC8 HDAC1	1.22e-04	24	81	3	GO:0004407
GeneOntologyMolecularFunction	protein lysine deacetylase activity	HDAC3 HDAC8 HDAC1	1.39e-04	25	81	3	GO:0033558
GeneOntologyMolecularFunction	deacetylase activity	HDAC3 HDAC8 HDAC1	5.70e-04	40	81	3	GO:0019213
GeneOntologyBiologicalProcess	protein ubiquitination	TRAF3IP2 HDAC3 PARP10 AMER1 UBR5 KLHDC3 FANCI KCTD10 HDAC8 USP7 EIPR1 DCAF4 VCP	1.77e-05	811	82	13	GO:0016567
GeneOntologyBiologicalProcess	regulation of TOR signaling	HDAC3 RELN ITFG2 USP7 MAPKAPK5 F7	3.98e-05	158	82	6	GO:0032006
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	TRAF3IP2 HDAC3 PARP10 AMER1 UBR5 KLHDC3 FANCI KCTD10 HDAC8 USP7 EIPR1 DCAF4 VCP	4.82e-05	893	82	13	GO:0032446
GeneOntologyBiologicalProcess	DNA repair	DPF1 HINFP PARP10 LIG1 SETD2 MEIOC UBR5 FANCI USP7 POLQ VCP	5.00e-05	648	82	11	GO:0006281
GeneOntologyBiologicalProcess	intracellular transport	TRAF3IP2 HDAC3 SETD2 MDN1 MIA2 UBR5 ENTR1 USP7 IPO13 HRC SCRIB EIPR1 ANKRD50 BBS12 VCP PCNT KPNB1	6.83e-05	1496	82	17	GO:0046907
GeneOntologyBiologicalProcess	DNA metabolic process	DPF1 HINFP PARP10 LIG1 SETD2 MEIOC UBR5 KLHDC3 FANCI HDAC8 USP7 POLQ MAPKAPK5 VCP	8.46e-05	1081	82	14	GO:0006259
GeneOntologyBiologicalProcess	TOR signaling	HDAC3 RELN ITFG2 USP7 MAPKAPK5 F7	8.47e-05	181	82	6	GO:0031929
GeneOntologyBiologicalProcess	translesion synthesis	PARP10 POLQ VCP	1.47e-04	26	82	3	GO:0019985
GeneOntologyBiologicalProcess	cell cycle process	DPF1 HINFP HDAC3 LIG1 TMEM67 SETD2 MYBBP1A KIF2B MEIOC KLHDC3 ENTR1 HDAC8 NCAPH VCP PCNT KPNB1	1.52e-04	1441	82	16	GO:0022402
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	TRAF3IP2 HDAC3 PARP10 AMER1 UBR5 KLHDC3 FANCI KCTD10 HDAC8 USP7 EIPR1 DCAF4 VCP	1.64e-04	1009	82	13	GO:0070647
GeneOntologyBiologicalProcess	growth plate cartilage chondrocyte proliferation	CER1 DSPP	2.32e-04	6	82	2	GO:0003419
GeneOntologyBiologicalProcess	regulation of intracellular transport	HDAC3 SETD2 UBR5 USP7 HRC EIPR1 PCNT	2.54e-04	314	82	7	GO:0032386
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	TMEM67 SETD2 DSPP MMRN2 GBX2 SCRIB COQ7 RYR2	2.69e-04	421	82	8	GO:0060562
Domain	DUF3377	MMP24 MMP15 MMP16	3.13e-07	4	81	3	PF11857
Domain	His_deacetylse_1	HDAC3 HDAC8 HDAC1	3.13e-07	4	81	3	IPR003084
Domain	Pept_M10A_metallopeptidase_C	MMP24 MMP15 MMP16	3.13e-07	4	81	3	IPR021805
Domain	Hist_deacetyl	HDAC3 HDAC8 HDAC1	1.26e-05	11	81	3	PF00850
Domain	His_deacetylse_dom	HDAC3 HDAC8 HDAC1	1.26e-05	11	81	3	IPR023801
Domain	-	HDAC3 HDAC8 HDAC1	1.26e-05	11	81	3	3.40.800.20
Domain	His_deacetylse	HDAC3 HDAC8 HDAC1	1.26e-05	11	81	3	IPR000286
Domain	Hemopexin_CS	MMP24 MMP15 MMP16	5.11e-05	17	81	3	IPR018486
Domain	Pept_M10A_stromelysin-type	MMP24 MMP15 MMP16	6.12e-05	18	81	3	IPR016293
Domain	PG_binding_1	MMP24 MMP15 MMP16	8.49e-05	20	81	3	PF01471
Domain	Peptidoglycan-bd-like	MMP24 MMP15 MMP16	8.49e-05	20	81	3	IPR002477
Domain	Hemopexin-like_dom	MMP24 MMP15 MMP16	1.31e-04	23	81	3	IPR000585
Domain	Hemopexin-like_repeat	MMP24 MMP15 MMP16	1.31e-04	23	81	3	IPR018487
Domain	M10A_MMP	MMP24 MMP15 MMP16	1.31e-04	23	81	3	IPR033739
Domain	Hemopexin	MMP24 MMP15 MMP16	1.31e-04	23	81	3	PF00045
Domain	HEMOPEXIN	MMP24 MMP15 MMP16	1.31e-04	23	81	3	PS00024
Domain	-	MMP24 MMP15 MMP16	1.31e-04	23	81	3	2.110.10.10
Domain	HEMOPEXIN_2	MMP24 MMP15 MMP16	1.31e-04	23	81	3	PS51642
Domain	HX	MMP24 MMP15 MMP16	1.31e-04	23	81	3	SM00120
Domain	Pept_M10A	MMP24 MMP15 MMP16	1.31e-04	23	81	3	IPR021190
Domain	Peptidase_M10	MMP24 MMP15 MMP16	1.49e-04	24	81	3	PF00413
Domain	ZnMc	MMP24 MMP15 MMP16	2.65e-04	29	81	3	SM00235
Domain	Peptidase_Metallo	MMP24 MMP15 MMP16	2.65e-04	29	81	3	IPR006026
Domain	CYSTEINE_SWITCH	MMP24 MMP15 MMP16	7.44e-04	41	81	3	PS00546
Domain	Pept_M10_metallopeptidase	MMP24 MMP15 MMP16	8.56e-04	43	81	3	IPR001818
Domain	IMPORTIN_B_NT	IPO13 KPNB1	1.63e-03	14	81	2	PS50166
Domain	Ferritin-like_SF	SETD2 COQ7	1.63e-03	14	81	2	IPR009078
Domain	Pept_M10A_Zn_BS	MMP15 MMP16	1.88e-03	15	81	2	IPR021158
Domain	IBN_N	IPO13 KPNB1	1.88e-03	15	81	2	PF03810
Domain	IBN_N	IPO13 KPNB1	2.14e-03	16	81	2	SM00913
Domain	Importin-beta_N	IPO13 KPNB1	2.42e-03	17	81	2	IPR001494
Domain	MetalloPept_cat_dom	MMP24 MMP15 MMP16	5.26e-03	81	81	3	IPR024079
Domain	-	MMP24 MMP15 MMP16	5.26e-03	81	81	3	3.40.390.10
Pubmed	Class I HDAC activity is required for renal protection and regeneration after acute kidney injury.	HDAC3 HDAC8 HDAC1	5.23e-08	4	83	3	24808536
Pubmed	Expression profile of class I histone deacetylases in human cancer tissues.	HDAC3 HDAC8 HDAC1	5.23e-08	4	83	3	17786334
Pubmed	Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC).	MMP24 MMP15 MMP16	5.23e-08	4	83	3	35062057
Pubmed	Class I histone deacetylase activity is required for proliferation of renal epithelial cells.	HDAC3 HDAC8 HDAC1	5.23e-08	4	83	3	23698124
Pubmed	Expression of class I histone deacetylases during chick and mouse development.	HDAC3 HDAC8 HDAC1	5.23e-08	4	83	3	20979029
Pubmed	Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription.	HDAC3 HDAC8 HDAC1	1.31e-07	5	83	3	28497810
Pubmed	Class I HDACs specifically regulate E-cadherin expression in human renal epithelial cells.	HDAC3 HDAC8 HDAC1	1.31e-07	5	83	3	27420561
Pubmed	HDAC3 Deficiency Promotes Liver Cancer through a Defect in H3K9ac/H3K9me3 Transition.	HDAC3 HDAC8 HDAC1	1.31e-07	5	83	3	31097476
Pubmed	mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue.	MMP24 MMP15 MMP16	1.31e-07	5	83	3	12661033
Pubmed	MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding.	MMP24 MMP15 MMP16	1.31e-07	5	83	3	29196321
Pubmed	HIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages.	HDAC3 HDAC8 HDAC1	2.61e-07	6	83	3	26679995
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	MYBBP1A MDN1 AARS2 PRPF4 FANCI CANX USP7 SCRIB VCP HDAC1 KPNB1	3.55e-07	638	83	11	33239621
Pubmed	Class I histone deacetylases in retinal progenitors and differentiating ganglion cells.	HDAC3 HDAC8 HDAC1	4.56e-07	7	83	3	30179675
Pubmed	Membrane-type matrix metalloproteinases: Their functions and regulations.	MMP24 MMP15 MMP16	4.56e-07	7	83	3	25794647
Pubmed	ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain.	HDAC3 HDAC8 HDAC1	7.28e-07	8	83	3	11533236
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	POLR1F HDAC3 SETD2 MYBBP1A MDN1 UBR5 PRPF4 FANCI USP7 NCAPH MED13 VCP HDAC1	8.17e-07	1014	83	13	32416067
Pubmed	Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development.	HDAC3 HDAC8 HDAC1	1.09e-06	9	83	3	15367668
Pubmed	Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2.	HDAC3 HDAC8 HDAC1	1.09e-06	9	83	3	26221039
Pubmed	Class II histone deacetylases: versatile regulators.	HDAC3 HDAC8 HDAC1	1.55e-06	10	83	3	12711221
Pubmed	Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing.	HDAC3 HDAC1 KPNB1	1.55e-06	10	83	3	17172643
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DPF1 SETD2 UBR5 PRPF4 ENTR1 APBA2 ADNP2 USP7 SCRIB ABCA7 SLC39A7 VCP HDAC1	2.35e-06	1116	83	13	31753913
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYBBP1A MDN1 UBR5 FANCI CANX BYSL USP7 VCP PCNT KPNB1	3.61e-06	653	83	10	22586326
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	POLR1F UBR5 PRPF4 FANCI KCTD10 APBA2 USP7 SCRIB F7 DCAF4 SLC39A7 VCP	4.67e-06	1005	83	12	19615732
Pubmed	Histone deacetylase expression patterns in developing murine optic nerve.	HDAC3 HDAC8 HDAC1	4.68e-06	14	83	3	25011550
Pubmed	Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis.	HDAC3 HDAC8 HDAC1	4.68e-06	14	83	3	15537544
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	POLR1F MDN1 MIA2 UBR5 USP7 NCAPH SLC39A7 HDAC1	5.21e-06	399	83	8	37536630
Pubmed	Alcohol-induced serotonergic modulation: the role of histone deacetylases.	HDAC3 HDAC1	5.63e-06	2	83	2	22796363
Pubmed	Histone deacetylases and the immunological network: implications in cancer and inflammation.	HDAC3 HDAC1	5.63e-06	2	83	2	19855430
Pubmed	HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin.	HDAC3 HDAC1	5.63e-06	2	83	2	27550312
Pubmed	Characterization of interaction and ubiquitination of phosphoenolpyruvate carboxykinase by E3 ligase UBR5.	UBR5 PCK1	5.63e-06	2	83	2	30552140
Pubmed	The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+).	HRC RYR2	5.63e-06	2	83	2	24805197
Pubmed	Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family.	MMP15 MMP16	5.63e-06	2	83	2	7559440
Pubmed	Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.	HDAC3 HDAC1	5.63e-06	2	83	2	27109927
Pubmed	Histone deacetylase-1 (HDAC1) is a molecular switch between neuronal survival and death.	HDAC3 HDAC1	5.63e-06	2	83	2	22918830
Pubmed	Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively.	MMP15 MMP16	5.63e-06	2	83	2	9070935
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	MDN1 UBR5 FANCI CANX ENTR1 NCAPH VCP	6.02e-06	288	83	7	23383273
Pubmed	Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10.	HDAC3 HDAC8 HDAC1	7.18e-06	16	83	3	16873063
Pubmed	Matrix metalloproteinases in tumor invasion.	MMP24 MMP15 MMP16	7.18e-06	16	83	3	10949577
Pubmed	HDAC family: What are the cancer relevant targets?	HDAC3 HDAC8 HDAC1	1.04e-05	18	83	3	18824292
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	HDAC3 MYBBP1A UBR5 ITFG2 KLHDC3 FANCI MRPS24 ENTR1 USP7 EIPR1 POLQ SLC39A7 VCP	1.07e-05	1284	83	13	17353931
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CNTN4 RELN MIA2 NECAB1 CNST APBA2 ADNP2 USP7 SCRIB MED13 VCP PCNT KPNB1	1.08e-05	1285	83	13	35914814
Pubmed	The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.	MYBBP1A PRPF4 MRPS24 MAFA BYSL USP7	1.51e-05	220	83	6	31822558
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	MYBBP1A AMER1 UBR5 PRPF4 CANX MRPS24 ENTR1 APBA2 BYSL USP7 VCP HDAC1 KPNB1	1.61e-05	1335	83	13	29229926
Pubmed	Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo.	HDAC3 HDAC1	1.69e-05	3	83	2	30279482
Pubmed	HDAC1/2 and HDAC3 play distinct roles in controlling adult Meibomian gland homeostasis.	HDAC3 HDAC1	1.69e-05	3	83	2	38679196
Pubmed	Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2.	UBR5 PAIP2	1.69e-05	3	83	2	16601676
Pubmed	USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork.	USP7 VCP	1.69e-05	3	83	2	34644576
Pubmed	CCN5, a novel transcriptional repressor of the transforming growth factor β signaling pathway.	HDAC3 HDAC1	1.69e-05	3	83	2	21262769
Pubmed	Regulation of the HIF-1alpha stability by histone deacetylases.	HDAC3 HDAC1	1.69e-05	3	83	2	17273746
Pubmed	STAT3 repressed USP7 expression is crucial for colon cancer development.	USP7 HDAC1	1.69e-05	3	83	2	22750444
Pubmed	Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer.	HDAC3 HDAC1	1.69e-05	3	83	2	19099586
Pubmed	Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy.	HDAC3 HDAC1	1.69e-05	3	83	2	18212746
Pubmed	Histone deacetylase 1 and 3 regulate the mesodermal lineage commitment of mouse embryonic stem cells.	HDAC3 HDAC1	1.69e-05	3	83	2	25412078
Pubmed	Expression and subcellular distribution of imp13 are regulated in brain development.	IPO13 KPNB1	1.69e-05	3	83	2	23605716
Pubmed	HDAC1/HDAC3 modulates PPARG2 transcription through the sumoylated CEBPD in hepatic lipogenesis.	HDAC3 HDAC1	1.69e-05	3	83	2	18619497
Pubmed	Role of the LXCXE binding site in Rb function.	HDAC3 HDAC1	1.69e-05	3	83	2	10958676
Pubmed	The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications.	HDAC3 HDAC1	1.69e-05	3	83	2	18854353
Pubmed	Combination of polymorphisms within the HDAC1 and HDAC3 gene predict tumor recurrence in hepatocellular carcinoma patients that have undergone transplant therapy.	HDAC3 HDAC1	1.69e-05	3	83	2	20731616
Pubmed	Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2.	HINFP HDAC1	1.69e-05	3	83	2	11553631
Pubmed	Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells.	HDAC8 HDAC1	1.69e-05	3	83	2	15590418
Pubmed	Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.	HDAC3 HDAC1	1.69e-05	3	83	2	33637599
Pubmed	Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo.	HDAC3 HDAC1	1.69e-05	3	83	2	18347167
Pubmed	The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.	HDAC3 HDAC1	1.69e-05	3	83	2	23087373
Pubmed	Nuclear Smad7 Overexpressed in Mesenchymal Cells Acts as a Transcriptional Corepressor by Interacting with HDAC-1 and E2F to Regulate Cell Cycle.	HDAC3 HDAC1	1.69e-05	3	83	2	23213415
Pubmed	Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells.	HDAC3 HDAC1	1.69e-05	3	83	2	20484017
Pubmed	Expression patterns of histone deacetylases in bovine oocytes and early embryos, and the effect of their inhibition on embryo development.	HDAC3 HDAC1	1.69e-05	3	83	2	11358320
Pubmed	Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression.	HDAC3 HDAC1	1.69e-05	3	83	2	15711539
Pubmed	Type-specific roles of histone deacetylase (HDAC) overexpression in ovarian carcinoma: HDAC1 enhances cell proliferation and HDAC3 stimulates cell migration with downregulation of E-cadherin.	HDAC3 HDAC1	1.69e-05	3	83	2	20049841
Pubmed	A cancer cell metalloprotease triad regulates the basement membrane transmigration program.	MMP15 MMP16	1.69e-05	3	83	2	16983145
Pubmed	Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells.	HDAC3 HDAC1	1.69e-05	3	83	2	24821725
Pubmed	Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization.	MMP15 MMP16	1.69e-05	3	83	2	9119382
Pubmed	Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos.	HDAC3 HDAC1	1.69e-05	3	83	2	18501342
Pubmed	Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.	HDAC3 HDAC1	1.69e-05	3	83	2	18789002
Pubmed	Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines.	HDAC8 HDAC1	1.69e-05	3	83	2	32591593
Pubmed	HDAC inhibition activates the apoptosome via Apaf1 upregulation in hepatocellular carcinoma.	HDAC3 HDAC1	1.69e-05	3	83	2	27342975
Pubmed	Comprehensive characterization of migration profiles of murine cerebral cortical neurons during development using FlashTag labeling.	RELN GBX2	1.69e-05	3	83	2	33851097
Pubmed	Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation.	HDAC3 HDAC1	1.69e-05	3	83	2	23475113
Pubmed	Class I histone deacetylases 1, 2 and 3 are highly expressed in classical Hodgkin's lymphoma.	HDAC3 HDAC1	1.69e-05	3	83	2	20415600
Pubmed	Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation.	HDAC3 PCK1	1.69e-05	3	83	2	21406501
Pubmed	Expression of histone deacetylases 1, 2 and 3 in histological subtypes of testicular germ cell tumours.	HDAC3 HDAC1	1.69e-05	3	83	2	21972094
Pubmed	Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells.	HDAC3 HDAC1	1.69e-05	3	83	2	33670166
Pubmed	Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.	HDAC3 HDAC1	1.69e-05	3	83	2	11006275
Pubmed	Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT.	HRC RYR2	1.69e-05	3	83	2	26410369
Pubmed	Structure of the human UBR5 E3 ubiquitin ligase.	UBR5 PCK1	1.69e-05	3	83	2	37040767
Pubmed	Molecular determinants of PAM2 recognition by the MLLE domain of poly(A)-binding protein.	UBR5 PAIP2	1.69e-05	3	83	2	20096703
Pubmed	Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells.	HDAC3 HDAC1	1.69e-05	3	83	2	21179472
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	POLR1F MYBBP1A MDN1 UBR5 MAP4K3 FANCI BYSL ADNP2 USP7 SCRIB NCAPH VCP KPNB1	1.85e-05	1353	83	13	29467282
Pubmed	Functional interactions between matrix metalloproteinases and glycosaminoglycans.	MMP24 MMP15 MMP16	1.95e-05	22	83	3	23421805
Pubmed	Matrix metalloproteinases.	MMP24 MMP15 MMP16	1.95e-05	22	83	3	10419448
Pubmed	Defining the membrane proteome of NK cells.	MYBBP1A MDN1 MIA2 UBR5 CNST FANCI CANX BYSL NCAPH MED13 PCNT KPNB1	2.09e-05	1168	83	12	19946888
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	AMER1 UBR5 PRPF4 FANCI MRPS24 ENTR1 F7 VCP HDAC1	2.21e-05	639	83	9	23443559
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	ARHGAP32 SETD2 MYBBP1A PRPF4 CANX MRPS24 BYSL POLQ	2.50e-05	496	83	8	31343991
Pubmed	Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.	MMP24 MMP15 MMP16	2.56e-05	24	83	3	15734845
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	HINFP ARHGAP32 MYBBP1A CCNYL1 MDN1 FANCI DCAF4	2.68e-05	363	83	7	14691545
Pubmed	Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression.	HDAC3 HDAC8 HDAC1	3.27e-05	26	83	3	23506836
Pubmed	Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappaB activation and transformation in resistant JB6 cells.	HDAC3 HDAC1	3.37e-05	4	83	2	15192014
Pubmed	Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3.	HDAC3 HDAC1	3.37e-05	4	83	2	21059642
Pubmed	Inactivation of CREB mediated gene transcription by HDAC8 bound protein phosphatase.	HDAC8 HDAC1	3.37e-05	4	83	2	19070599
Pubmed	The splicing regulator SLU7 is required to preserve DNMT1 protein stability and DNA methylation.	USP7 HDAC1	3.37e-05	4	83	2	34331453
Pubmed	Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family.	HDAC3 HDAC1	3.37e-05	4	83	2	9346952
Interaction	FOXL1 interactions	HDAC3 MDN1 MID1IP1 AARS2 CANX USP7 SCRIB NCAPH	1.47e-06	196	83	8	int:FOXL1
Cytoband	6p21.1	AARS2 KLHDC3 BYSL DNPH1	1.41e-05	80	83	4	6p21.1
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	HDAC3 HDAC8 HDAC1	1.19e-07	4	57	3	989
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP24 MMP15 MMP16	5.74e-05	24	57	3	891
GeneFamily	Armadillo repeat containing\|Importins	IPO13 KPNB1	1.45e-03	18	57	2	596
Coexpression	TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C	DENND5B LIG1 ARHGAP32 SETD2 MDN1 ITFG2 MANEAL HDAC8 KPNB1	1.37e-05	454	83	9	M19927
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	MDN1 CNST KLHDC3 HDAC8 APBA2 USP7	3.09e-05	189	83	6	M3112
Coexpression	GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP	MDN1 CNST DSPP MRPS24 MAPKAPK5 ABCA7	3.90e-05	197	83	6	M6512
Coexpression	GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN	TRAF3IP2 KCTD10 ENTR1 RIMOC1 ABCA7 HDAC1	4.12e-05	199	83	6	M4142
Coexpression	GSE17580_TREG_VS_TEFF_UP	LIG1 MDN1 KLHDC3 DNPH1 DCAF4 VCP	4.24e-05	200	83	6	M3670
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_200	CNTN4 IGFBP2 COL6A5 RYR2	1.62e-05	40	81	4	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	CANX ENTR1 USP7 DNPH1 MED13 RYR2 VCP KPNB1	1.10e-04	385	81	8	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	CANX USP7 MMP16 ZC3H6 MED13 RYR2 VCP KPNB1	1.36e-04	397	81	8	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#5_top-relative-expression-ranked_200	MED13 RYR2 VCP KPNB1	1.41e-04	69	81	4	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500	CANX ENTR1 MED13 RYR2 VCP KPNB1	1.49e-04	209	81	6	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_500	CNTN4 IGFBP2 COL6A5 RYR2	1.94e-04	75	81	4	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500	CNTN4 CANX MMP16 MED13 RYR2 KPNB1	2.55e-04	231	81	6	gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	DPF1 SETD2 UBR5 MANEAL PCNT KPNB1	2.55e-04	231	81	6	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	CANX USP7 MMP16 MED13 RYR2 VCP KPNB1	2.67e-04	330	81	7	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LIG1 FANCI POLQ NCAPH F7	1.61e-05	169	83	5	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LIG1 FANCI OMD POLQ NCAPH	1.61e-05	169	83	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LIG1 FANCI OMD POLQ NCAPH	1.61e-05	169	83	5	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPF1 LIG1 CCNYL1 FANCI DNPH1	1.76e-05	172	83	5	2b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell	systemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DPF1 MMP24 IGFBP2 NECAB1 ZSCAN23	2.56e-05	186	83	5	ffd4510b4435d9bf94c2ef14c629f73ab78c5d93
ToppCell	systemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DPF1 MMP24 IGFBP2 NECAB1 ZSCAN23	2.69e-05	188	83	5	c613c6c7b6de8ed514253c9f9b8622c56fcc1452
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	LIG1 FANCI POLQ NCAPH KPNB1	2.76e-05	189	83	5	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTN4 IGFBP2 NECAB1 HRC RYR2	2.98e-05	192	83	5	5000440dc1ed17e7474d340921bdff945646f27e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DPF1 LIG1 FANCI POLQ NCAPH	3.05e-05	193	83	5	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	3'_v3-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	LIG1 IGFBP2 FANCI POLQ NCAPH	3.13e-05	194	83	5	bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DPF1 LIG1 FANCI POLQ NCAPH	3.21e-05	195	83	5	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	LIG1 FANCI POLQ NCAPH PCNT	3.21e-05	195	83	5	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AARS2 FANCI MANEAL BYSL POLQ	3.21e-05	195	83	5	5812b1615676f3b77eb4769216b98b360c417c0d
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LIG1 FANCI OMD POLQ NCAPH	3.45e-05	198	83	5	f088badb90c6c2d916195f5649eda102119c9ac6
ToppCell	mLN-T_cell-cycling_gd_T\|mLN / Region, Cell class and subclass	MMP24 IGFBP2 FANCI POLQ NCAPH	3.62e-05	200	83	5	4efeef51f885ee8f6dd3911a536cc49e3c14da98
ToppCell	mLN-(1)_T_cell-(18)_cycling_gd_T\|mLN / shred on region, Cell_type, and subtype	MMP24 IGFBP2 FANCI POLQ NCAPH	3.62e-05	200	83	5	e8a0a88a8344e80783931115bbe6cd5b62a4c1f7
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	CNTN4 MIA2 FANCI POLQ NCAPH	3.62e-05	200	83	5	0bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	CNTN4 MIA2 FANCI POLQ NCAPH	3.62e-05	200	83	5	c9479452ab8c51139522383f745f02171ebbd7e2
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LIG1 FANCI POLQ NCAPH PCNT	3.62e-05	200	83	5	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Pvalb_(Layer_5a)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KIF2B F7 PCK1	1.18e-04	51	83	3	28d6b12c44ad308560931d275e0dd0243a555bf3
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	HINFP APBA2 BYSL RBBP8NL	1.82e-04	151	83	4	8ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN IGFBP2 NECAB1 CPS1	1.87e-04	152	83	4	8ff5a178a8f3550d89a003c0858820aab3773386
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HINFP DOK1 MDN1 APBA2	1.97e-04	154	83	4	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 COL6A5 CPS1 RYR2	2.27e-04	160	83	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTN4 COL6A5 CPS1 RYR2	2.27e-04	160	83	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AARS2 FANCI POLQ NCAPH	2.27e-04	160	83	4	8a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	MMP24 MORN1 MMRN2 NCAPH	2.39e-04	162	83	4	a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOK1 CNTN4 OMD NCAPH	2.56e-04	165	83	4	4f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGFBP2 MANEAL GBX2 NCAPH	2.56e-04	165	83	4	c042cde64b61ae195e1054f7b560151dabbfdf0d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOK1 CNTN4 OMD NCAPH	2.56e-04	165	83	4	cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MMP24 FANCI MMRN2 NCAPH	2.56e-04	165	83	4	a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 MID1IP1 DNPH1 RBBP8NL	2.62e-04	166	83	4	575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LIG1 FANCI POLQ NCAPH	2.68e-04	167	83	4	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LIG1 FANCI OMD POLQ	2.68e-04	167	83	4	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 MID1IP1 FANCI PCNT	2.87e-04	170	83	4	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTN4 ARHGAP32 ANKRD50 RYR2	2.87e-04	170	83	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPF1 FANCI POLQ NCAPH	2.93e-04	171	83	4	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPF1 FANCI POLQ NCAPH	2.93e-04	171	83	4	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	LIG1 APBA2 POLQ NCAPH	2.93e-04	171	83	4	4ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell	facs-Heart-RV-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN IGFBP2 COL6A5 DCAF4	3.00e-04	172	83	4	a26a73c41e5a05c9dd47a99f3320295f684c5e54
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	LIG1 FANCI POLQ NCAPH	3.00e-04	172	83	4	8d20eda599abf1e9e3e3b90f314acddee6a465a4
ToppCell	10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK\|bone_marrow / Manually curated celltypes from each tissue	LIG1 FANCI POLQ NCAPH	3.06e-04	173	83	4	8a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP32 MMRN2 SCRIB NCAPH	3.06e-04	173	83	4	12f779b8dce79431b2d1002ba524dd3f9566aeb0
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNYL1 MMRN2 GBX2 SLC39A7	3.06e-04	173	83	4	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTN4 IGFBP2 NECAB1 MMP16	3.13e-04	174	83	4	bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell	ASK452-Immune-NK_cell\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	MIA2 APBA2 NCAPH HDAC1	3.13e-04	174	83	4	b84e6dc1c003a677234ce3a818650ff58a45dd09
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	DNPH1 NCAPH BBS12 RYR2	3.13e-04	174	83	4	e324320b52c904496e26fcecfa179b3431729ec0
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN AARS2 NECAB1 APBA2	3.20e-04	175	83	4	9d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DENND5B FANCI POLQ NCAPH	3.20e-04	175	83	4	89bf89466191da14896ed8928027f5b911436c22
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOK1 OMD POLQ NCAPH	3.20e-04	175	83	4	f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN AARS2 NECAB1 APBA2	3.20e-04	175	83	4	f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCell	10x3'2.3-week_17-19-Neuro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CNTN4 GAL3ST1 MANEAL MMP15	3.20e-04	175	83	4	bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCell	10x3'2.3-week_17-19-Neuro-stroma-schwann_cells\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CNTN4 GAL3ST1 MANEAL MMP15	3.20e-04	175	83	4	8b010220cdfb680ec839572f4933adfb85045ea6
ToppCell	10x3'2.3-week_17-19-Neuro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CNTN4 GAL3ST1 MANEAL MMP15	3.20e-04	175	83	4	0b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	PRPF4 FANCI POLQ NCAPH	3.34e-04	177	83	4	ba701d3c90722d8bff70d0fa651899305cdad257
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND5B MMRN2 POLQ MMP15	3.41e-04	178	83	4	ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIG1 ARHGAP32 CCNYL1 NCAPH	3.48e-04	179	83	4	9dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIF2B FANCI POLQ NCAPH	3.48e-04	179	83	4	e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	IGFBP2 FANCI POLQ NCAPH	3.63e-04	181	83	4	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA2 CPS1 MMP15 F7	3.71e-04	182	83	4	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	LIG1 FANCI POLQ NCAPH	3.71e-04	182	83	4	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA2 CPS1 MMP15 F7	3.71e-04	182	83	4	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA2 CPS1 MMP15 F7	3.71e-04	182	83	4	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BYSL ADNP2 DCAF4 MED13	3.79e-04	183	83	4	3ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LIG1 FANCI POLQ NCAPH	3.95e-04	185	83	4	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	DPF1 FANCI POLQ NCAPH	3.95e-04	185	83	4	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGFBP2 NECAB1 MMRN2 MMP16	4.03e-04	186	83	4	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LIG1 FANCI POLQ NCAPH	4.03e-04	186	83	4	993c58ef4445bf81bbc9b489635883848b5b4c8e
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRAF3IP2 MRPS24 DNPH1 NCAPH	4.03e-04	186	83	4	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LIG1 FANCI POLQ NCAPH	4.11e-04	187	83	4	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIG1 FANCI POLQ NCAPH	4.19e-04	188	83	4	61ae7405ab56570409bf35382dc0a038e4137c15
ToppCell	NS-critical-d_0-4-Lymphoid-NKT-proliferating\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LIG1 FANCI POLQ NCAPH	4.28e-04	189	83	4	d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIG1 FANCI POLQ NCAPH	4.28e-04	189	83	4	fd8834d1feb7f63911c5fa51efb1f679a8baddeb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP32 NECAB1 MMP16 RYR2	4.28e-04	189	83	4	a75226616340045b581d08429d2e123e041dee55
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGFBP2 NECAB1 MMRN2 MMP16	4.28e-04	189	83	4	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP32 NECAB1 MMP16 RYR2	4.36e-04	190	83	4	d594da827e3c16644952b9589cc12b947ce36279
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PRPF4 MAP4K3 KLHDC3 MAPKAPK5	4.36e-04	190	83	4	651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCell	PBMC-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	LIG1 FANCI NCAPH KPNB1	4.36e-04	190	83	4	84ee185939bdefb10705b621a70da27701eadcee
ToppCell	Severe-Lymphoid-T-NK\|Severe / Condition, Lineage, Cell class and cell subclass	FANCI APBA2 OMD POLQ	4.36e-04	190	83	4	60642de433f84fa2cecd796c3a1a4aab9219d3db
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LIG1 TMEM67 FANCI PCNT	4.36e-04	190	83	4	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LIG1 FANCI POLQ NCAPH	4.36e-04	190	83	4	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP32 NECAB1 MMP16 RYR2	4.36e-04	190	83	4	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LIG1 FANCI POLQ NCAPH	4.45e-04	191	83	4	15dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCell	wk_20-22-Hematologic_Lymphocytic-NK-Cycling_NK\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LIG1 FANCI POLQ NCAPH	4.45e-04	191	83	4	5d4fed25bd318472a17228b12ade4c331865bda5
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LIG1 FANCI POLQ NCAPH	4.45e-04	191	83	4	45c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGFBP2 NECAB1 MMRN2 MMP16	4.45e-04	191	83	4	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Undetermined\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	LIG1 FANCI NCAPH HDAC1	4.54e-04	192	83	4	3856c4d611224cd6c2558631147cd5333bc0ccb7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CANX DNPH1 SLC39A7 VCP	4.63e-04	193	83	4	43ffa8ecc72bebcd204279db2bde98ae48d97f90
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LIG1 FANCI POLQ NCAPH	4.63e-04	193	83	4	bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LIG1 FANCI POLQ NCAPH	4.63e-04	193	83	4	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	FANCI ADNP2 USP7 KPNB1	4.63e-04	193	83	4	c2673d86f7d7b849788036032a93a6d136a70040
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LIG1 FANCI POLQ NCAPH	4.63e-04	193	83	4	cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-Cycling_T\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LIG1 FANCI POLQ NCAPH	4.63e-04	193	83	4	81e6240cffb094b2aa3684fd0889b6497f47c4f0
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RELN USP7 ABCA7 PCNT	4.63e-04	193	83	4	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	control-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LIG1 FANCI POLQ NCAPH	4.63e-04	193	83	4	ecb4018a47d9a82bb999e0bc8b3dceabd97d1f0d
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LIG1 FANCI NCAPH PCNT	4.63e-04	193	83	4	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LIG1 FANCI POLQ NCAPH	4.72e-04	194	83	4	f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FANCI POLQ NCAPH VCP	4.72e-04	194	83	4	17af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LIG1 FANCI POLQ NCAPH	4.72e-04	194	83	4	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FANCI POLQ NCAPH VCP	4.72e-04	194	83	4	3c385d93c5fe1a7817813c492f79fdb94d887357
Drug	Rodeo	HDAC3 KLHDC3 HDAC8 HDAC1	3.77e-07	17	83	4	CID000038078
Drug	Vorinostat	HDAC3 HDAC8 HDAC1	4.65e-07	5	83	3	DB02546
Drug	AC1MQZ6I	MMP24 PAIP2 MMP15 MMP16 PCK1 HDAC1 KPNB1	6.13e-06	190	83	7	CID003509873
Drug	Miconazole [22916-47-8]; Down 200; 9.6uM; PC3; HT_HG-U133A	ARHGAP32 ITFG2 DSPP USP7 CPS1 DNPH1 COQ7	7.52e-06	196	83	7	6615_DN
Drug	Pimelic Acids	HDAC3 HDAC1	1.31e-05	2	83	2	ctd:D010867
Drug	AC1NV99J	HDAC3 HDAC8 HDAC1	2.53e-05	16	83	3	CID005474719
Drug	MMI270	MMP24 MMP15 MMP16	3.66e-05	18	83	3	CID000446504
Drug	AC1L1EXH	HDAC3 HDAC8 HDAC1	3.66e-05	18	83	3	CID000002992
Drug	trapoxin B	HDAC3 HDAC1	3.93e-05	3	83	2	ctd:C067071
Drug	5,6-dimethyl-1,10-phenanthroline	DSPP CANX	3.93e-05	3	83	2	CID000076357
Disease	susceptibility to mononucleosis measurement	MDN1 ANKRD50 RYR2	9.50e-04	69	82	3	EFO_0008403
Disease	colorectal cancer (is_marker_for)	HDAC3 SETD2 AMER1 HDAC1	9.77e-04	157	82	4	DOID:9256 (is_marker_for)
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	SETD2 MED13	1.01e-03	17	82	2	DOID:0060307 (is_implicated_in)
Disease	type 1 diabetes mellitus (is_marker_for)	HDAC3 F7 HDAC1	1.07e-03	72	82	3	DOID:9744 (is_marker_for)
Disease	Bardet-Biedl syndrome	TMEM67 BBS12	1.13e-03	18	82	2	cv:C0752166
Disease	diabetes mellitus (biomarker_via_orthology)	MAFA F7	1.27e-03	19	82	2	DOID:9351 (biomarker_via_orthology)
Disease	hypothyroidism (biomarker_via_orthology)	RELN IGFBP2 F7	1.46e-03	80	82	3	DOID:1459 (biomarker_via_orthology)
Disease	quinolinic acid measurement	CNTN4 CPS1	1.55e-03	21	82	2	EFO_0010528
Disease	Down syndrome (is_marker_for)	RELN PCNT	1.70e-03	22	82	2	DOID:14250 (is_marker_for)
Disease	prostate cancer, disease progression measurement	RBBP8NL F7	2.02e-03	24	82	2	EFO_0008336, MONDO_0008315

Protein segments in the cluster

Peptide	Gene	Start	Entry
HVHEEEGILVAVGQD	DCAF4	421	Q8WV16
GGAAGRSHHLDEDEE	KCTD10	276	Q9H3F6
GEEAAGGDRLIHEQD	DNPH1	66	O43598
HTHLAEEEGEENAER	DPF1	216	Q92782
NGHLIDFDRDGDHFE	CNTN4	536	Q8IWV2
HDGLSEAAHGPEDVV	AMER1	96	Q5JTC6
EGQDHGKEDDHDSSI	DSPP	281	Q9NZW4
EPSVLEAHDQEEDGH	APBA2	171	Q99767
LLDHGAEVNHEDVDG	ANKRD50	696	Q9ULJ7
GHIDVVQVLLEHGAD	ANKRD50	1056	Q9ULJ7
EHEDGHILHAGSQDS	CER1	246	O95813
NDLVELAVGLSHGDH	BBS12	266	Q6ZW61
GEGEGHHLQHISDRE	CCNYL1	56	Q8N7R7
FGELAVHGAEHGVED	ABCA7	2071	Q8IZY2
PDGHLGAEDQRHGEE	ADNP2	981	Q6IQ32
EDVIINGHSHEDDNP	PAIP2	16	Q9BPZ3
DHIHICDGSEEENGR	PCK1	41	P35558
DLELHLGALHGQEDT	MORN1	326	Q5T089
QDIHGHLGDIDQDVE	FANCI	1051	Q9NVI1
HDGNDLFLVAVHELG	MMP24	271	Q9Y5R2
RGHVAHLEDDEGDDD	MAP4K3	406	Q8IVH8
ADDQDGDAAQHPEEH	MDN1	4961	Q9NU22
EDAVEALIGSGHHGA	MAFA	136	Q8NHW3
GHLEGADAGEEDLEQ	MID1IP1	131	Q9NPA3
IHDHENGAEDSNVAL	MAPKAPK5	376	Q8IW41
LYIDIDIHHGDGVEE	HDAC1	171	Q13547
EHLEPSHDAGREEAA	MMRN2	676	Q9H8L6
GLGVAAEDAEVHAEN	MMP15	41	P51511
DDHSEGGLVENHVDS	IGFBP2	151	P18065
HDNESEEEGGLLHIP	ARHGAP32	756	A7KAX9
EDEAGLHQSQAVHGL	PCNT	231	O95613
GHLVDDDDISDQEDH	EIPR1	311	Q53HC9
YIDIDIHHGDGVQEA	HDAC3	166	O15379
LDASGHHETLIGEEQ	ITFG2	101	Q969R8
HDLGERAGALHAQVE	MYBBP1A	891	Q9BQG0
THHGELEGDGEQGEV	RELN	41	P78509
HEEAEEDHQGVGLRG	RBBP8NL	166	Q8NC74
IDGGHAVDAAAIQDE	GAL3ST1	346	Q99999
AISEHVEDAGVHSGD	CPS1	1191	P31327
QAAHKEEDPGHALEE	GBX2	216	P52951
GHDVLRADSHEGEVA	DOK1	261	Q99704
HGTHFGDDRFEDLEE	ENTR1	91	Q96C92
PVLDEHHQGDQDGGD	POLQ	1596	O75417
HHQGDQDGGDQDERA	POLQ	1601	O75417
GESHDHDQLNDTALE	COL6A5	926	A8TX70
DEELEHHDIGLDHDA	COQ7	176	Q99807
AIVEAHDGHDDDVID	CANX	16	P27824
GHEAVELGHGEANIT	DENND5B	756	Q6ZUT9
IDHIAGDEDHTDGVV	KPNB1	801	Q14974
VEEGHTHDILAAGFD	MANEAL	306	Q5VSG8
GLGDEFDLIDHSDLH	KLHDC3	316	Q9BQ90
DLDLHHGDGVEDAFS	HDAC8	176	Q9BY41
QQHLHGSGEEEEEEE	HINFP	41	Q9BQA5
LGTGFSDEELEEHHQ	LIG1	796	P18858
HIGQHQFGEDLILED	RYR2	3111	Q92736
LDISHHEDDHEGPEL	IPO13	651	O94829
AAGHHAEVVVDPEDE	BYSL	116	Q13895
SDENENQLDGDGHEH	CNST	36	Q6PJW8
ENIQERAGGVHHDID	KIF2B	621	Q8N4N8
DAERVLAQADHELHG	PARP10	61	Q53GL7
ESPEQEGAEGHFDLH	OMD	401	Q99983
KNEEDGGADEHEHPL	MIA2	401	Q96PC5
GGADEHEHPLTSELD	MIA2	406	Q96PC5
DHGEAHVQTDIALGV	TMEM67	516	Q5HYA8
LHTGNLDGEDHAAER	MRPS24	71	Q96EL2
DELHHGFTGLDLEEQ	MEIOC	221	A2RUB1
AHIQQLSEAAGEDDH	RIMOC1	21	A6NDU8
DLEAQEEILHQEGHS	PRPF4	351	O43172
AVLGEHDLSEHDGDE	F7	266	P08709
LEVNGVALQGAEHHE	SCRIB	781	Q14160
HRHQGHGIEEDEDVS	HRC	271	P23327
EKGTHHGSRDQEDEE	HRC	506	P23327
FADLIHHDLSEEEDG	MED13	91	Q9UHV7
AGGHHNDLEDVGRDL	AARS2	111	Q5JTZ9
GAESQLDEDEHGLHT	TRAF3IP2	481	O43734
NDEPDHTAVGDHEEF	NCAPH	376	Q15003
HAGHDREDGELEDGE	ZC3H6	6	P61129
DGNDLFLVAVHELGH	MMP16	236	P51512
LEQVANETHGHVGAD	VCP	396	P55072
AGLGGHDDLHDDLQE	SLC39A7	26	Q92504
GAGVTLHEALEAADH	TKTL2	511	Q9H0I9
ELGDIYDDQGHIHLN	POLR1F	101	Q3B726
LDERGEGGHVHTSDD	SETD2	981	Q9BYW2
EEAIEHNYGGHDDDL	USP7	491	Q93009
EGVAGEEDHHDEQEE	UBR5	1576	O95071
HGEENAEAEGQHDEH	UBR5	1591	O95071
DDPGEQVLSHAHEQE	ZSCAN23	131	Q3MJ62
ADGVLSGEELHELFH	NECAB1	56	Q8N987