Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription corepressor binding

PER3 PER2 PER1 EHMT1

7.92e-0559774GO:0001222
GeneOntologyMolecularFunctionextracellular matrix structural constituent

SLIT2 THBS3 THBS4 FBN2 HMCN2 LAMC1

8.76e-05188776GO:0005201
GeneOntologyMolecularFunctioncargo receptor activity

INSR LRP1 CUBN LDLR

3.27e-0485774GO:0038024
GeneOntologyMolecularFunctionlaminin-1 binding

SLIT2 THBS4

4.05e-048772GO:0043237
GeneOntologyMolecularFunctionhistone H3K9 monomethyltransferase activity

SETDB1 EHMT1

4.05e-048772GO:0140948
GeneOntologyMolecularFunctioncalcium ion binding

SLIT2 THBS3 THBS4 FBN2 HMCN2 FAT3 LRP1 EML1 CUBN LDLR

5.88e-047497710GO:0005509
GeneOntologyMolecularFunctionhistone H3K9me2 methyltransferase activity

SETDB1 EHMT1

6.47e-0410772GO:0140947
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN2 LAMC1

9.45e-0412772GO:0030023
GeneOntologyMolecularFunctionclathrin heavy chain binding

LRP1 LDLR

9.45e-0412772GO:0032050
GeneOntologyMolecularFunctionhistone H3K9 methyltransferase activity

SETDB1 EHMT1

1.11e-0313772GO:0046974
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN2 LAMC1

1.30e-0314772GO:0097493
GeneOntologyBiologicalProcessprotein-DNA complex organization

SETDB1 ASXL1 KAT5 PER2 ERCC6L ATAD2B BCORL1 PER1 EHMT1 KDM3B SENP6 LAMC1 USP15 BAHCC1

1.48e-059997614GO:0071824
GeneOntologyBiologicalProcesschromatin organization

SETDB1 ASXL1 KAT5 PER2 ERCC6L ATAD2B BCORL1 PER1 EHMT1 KDM3B LAMC1 USP15 BAHCC1

2.17e-058967613GO:0006325
GeneOntologyBiologicalProcesscircadian regulation of translation

PER2 PER1

8.00e-054762GO:0097167
GeneOntologyBiologicalProcessentrainment of circadian clock by photoperiod

PER3 PER2 PER1

1.04e-0425763GO:0043153
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LDLR

1.33e-045762GO:1905167
GeneOntologyBiologicalProcessregulation of circadian rhythm

ADRB1 KAT5 PER3 PER2 PER1

1.42e-04135765GO:0042752
GeneOntologyBiologicalProcessphotoperiodism

PER3 PER2 PER1

1.47e-0428763GO:0009648
GeneOntologyBiologicalProcessnegative regulation of transforming growth factor beta receptor signaling pathway

MTMR4 FBN2 WFIKKN2 LRP1 USP15

1.57e-04138765GO:0030512
GeneOntologyBiologicalProcessregulation of lipopolysaccharide-mediated signaling pathway

TUT4 SASH1 CARD8

1.82e-0430763GO:0031664
GeneOntologyBiologicalProcessentrainment of circadian clock

PER3 PER2 PER1

1.82e-0430763GO:0009649
MousePhenoabnormal ocular fundus morphology

DDIT4 IQSEC3 THBS4 FBN2 SASH1 PER2 GUCY1A1 FAT3 BACH2 TMCC2 BCORL1 PEPD BBS1 LAMC1 PCARE EML1 MFRP CNGA1 LDLR MEIS1

7.93e-0712626620MP:0002864
MousePhenoabnormal retina morphology

DDIT4 IQSEC3 THBS4 SASH1 PER2 GUCY1A1 FAT3 TMCC2 BCORL1 PEPD BBS1 LAMC1 PCARE EML1 MFRP CNGA1 LDLR MEIS1

9.81e-0612276618MP:0001325
MousePhenoabnormal circadian sleep/wake cycle

PER2 PER1 MEIS1

2.15e-0512663MP:0020478
MousePhenoabnormal photoreceptor outer segment morphology

BBS1 PCARE EML1 MFRP CNGA1 LDLR

5.23e-05141666MP:0003729
MousePhenoabnormal circulating unsaturated transferrin level

BACH2 PEPD LDLR

1.08e-0420663MP:0011895
MousePhenoabnormal circulating transferrin level

BACH2 PEPD LDLR

1.45e-0422663MP:0011892
MousePhenoabnormal retina neuronal layer morphology

IQSEC3 GUCY1A1 FAT3 BBS1 PCARE EML1 MFRP CNGA1 LDLR

2.14e-04441669MP:0006069
MousePhenoabnormal sleep pattern

PER3 PER2 PER1 MEIS1

2.33e-0464664MP:0001501
MousePhenoshortened circadian behavior period

PER3 PER2 PER1

2.42e-0426663MP:0020470
MousePhenophotoreceptor outer segment degeneration

PCARE CNGA1 LDLR

2.71e-0427663MP:0008584
MousePhenodecreased a-wave amplitude

PCARE EML1 MFRP CNGA1

2.78e-0467664MP:0012143
MousePhenoabnormal photoreceptor inner segment morphology

BBS1 PCARE MFRP CNGA1

2.94e-0468664MP:0003730
MousePhenoabnormal a-wave amplitude

PCARE EML1 MFRP CNGA1

3.11e-0469664MP:0012030
MousePhenoabnormal a-wave shape

PCARE EML1 MFRP CNGA1

3.29e-0470664MP:0012034
MousePhenoabnormal retina photoreceptor morphology

BBS1 PCARE EML1 MFRP CNGA1 LDLR

4.15e-04206666MP:0001004
MousePhenoincreased memory-marker CD4-negative NK T cell number

BACH2 PEPD

4.54e-047662MP:0013514
MousePhenoabnormal retina photoreceptor layer morphology

BBS1 PCARE EML1 MFRP CNGA1 LDLR

5.20e-04215666MP:0003728
MousePhenoabnormal retina layer morphology

IQSEC3 GUCY1A1 FAT3 BBS1 PCARE EML1 MFRP CNGA1 LDLR

5.69e-04504669MP:0003727
MousePhenodecreased skeletal muscle size

ZNF106 WFIKKN2 INSR LAMC1

5.74e-0481664MP:0010240
MousePhenodecreased b-wave amplitude

PCARE EML1 MFRP CNGA1

6.01e-0482664MP:0012144
MousePhenoabnormal circadian behavior period

PER3 PER2 PER1

6.42e-0436663MP:0020468
MousePhenoretina cone cell degeneration

PCARE MFRP CNGA1

6.42e-0436663MP:0008444
MousePhenodisorganized photoreceptor outer segment

BBS1 PCARE MFRP

6.42e-0436663MP:0008586
MousePhenoabnormal circadian behavior

PER3 PER2 PER1 MEIS1

6.59e-0484664MP:0020467
MousePhenoabnormal skeletal muscle mass

ZNF106 FBN2 WFIKKN2 INSR LAMC1

6.82e-04149665MP:0004817
MousePhenoabnormal b-wave shape

PCARE EML1 MFRP CNGA1

6.89e-0485664MP:0012035
MousePhenoabnormal b-wave amplitude

PCARE EML1 MFRP CNGA1

6.89e-0485664MP:0012031
MousePhenoabnormal eye vasculature morphology

DDIT4 THBS4 SASH1 PER2 TMCC2 BCORL1 CNGA1 LDLR

7.18e-04415668MP:0031346
MousePhenoretina degeneration

BBS1 PCARE MFRP CNGA1

7.52e-0487664MP:0001326
MousePhenoarrhythmic circadian behavior persistence

PER2 PER1

7.74e-049662MP:0020472
MousePhenoincreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number

BACH2 PEPD

7.74e-049662MP:0013430
MousePhenoincreased memory-marker NK cell number

BACH2 PEPD

7.74e-049662MP:0013427
MousePhenoabnormal somatic nervous system morphology

ZNF106 FBN2 CLCA1 GUCY1A1 FAT3 BACH2 PEPD BBS1 PCARE EML1 MFRP CNGA1 LDLR

8.72e-0410256613MP:0002752
DomainEGF_Ca-bd_CS

SLIT2 THBS3 THBS4 FBN2 HMCN2 FAT3 LRP1 CUBN LDLR

1.39e-1097739IPR018097
DomainEGF_CA

SLIT2 THBS3 THBS4 FBN2 HMCN2 FAT3 LRP1 CUBN LDLR

1.67e-1099739PS01187
DomainEGF_CA

SLIT2 THBS3 THBS4 FBN2 HMCN2 FAT3 LRP1 CUBN LDLR

1.10e-09122739SM00179
DomainEGF-like_Ca-bd_dom

SLIT2 THBS3 THBS4 FBN2 HMCN2 FAT3 LRP1 CUBN LDLR

1.27e-09124739IPR001881
DomainEGF_CA

THBS3 THBS4 FBN2 HMCN2 FAT3 LRP1 CUBN LDLR

1.53e-0986738PF07645
DomainEGF-like_dom

SLIT2 THBS3 THBS4 FBN2 MALRD1 HMCN2 FAT3 LRP1 LAMC1 CUBN LDLR

3.26e-092497311IPR000742
DomainEGF_1

SLIT2 THBS3 THBS4 FBN2 MALRD1 HMCN2 FAT3 LRP1 LAMC1 CUBN LDLR

4.18e-092557311PS00022
DomainEGF-like_CS

SLIT2 THBS3 THBS4 FBN2 MALRD1 HMCN2 FAT3 LRP1 LAMC1 CUBN LDLR

5.32e-092617311IPR013032
DomainEGF_2

SLIT2 THBS3 THBS4 FBN2 MALRD1 HMCN2 FAT3 LRP1 LAMC1 CUBN LDLR

6.24e-092657311PS01186
DomainGrowth_fac_rcpt_

THBS3 THBS4 FBN2 HMCN2 INSR LRP1 LAMC1 CUBN LDLR

9.65e-09156739IPR009030
DomainEGF_3

SLIT2 THBS3 THBS4 FBN2 MALRD1 HMCN2 FAT3 LRP1 CUBN LDLR

2.55e-082357310PS50026
DomainEGF

SLIT2 THBS3 THBS4 FBN2 MALRD1 FAT3 LRP1 LAMC1 CUBN LDLR

2.55e-082357310SM00181
DomainPeriod_circadian-like_C

PER3 PER2 PER1

5.73e-083733IPR022728
DomainPeriod_C

PER3 PER2 PER1

5.73e-083733PF12114
DomainASX_HYDROXYL

SLIT2 FBN2 HMCN2 FAT3 LRP1 CUBN LDLR

1.24e-07100737PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SLIT2 FBN2 HMCN2 FAT3 LRP1 CUBN LDLR

1.86e-07106737IPR000152
DomainLDLR_class-A_CS

MALRD1 LRP1 MFRP LDLR

1.76e-0540734IPR023415
DomainLdl_recept_a

MALRD1 LRP1 MFRP LDLR

2.83e-0545734PF00057
Domain-

MALRD1 LRP1 MFRP LDLR

3.10e-05467344.10.400.10
DomainLDLRA_1

MALRD1 LRP1 MFRP LDLR

3.67e-0548734PS01209
DomainLDLRA_2

MALRD1 LRP1 MFRP LDLR

3.98e-0549734PS50068
DomainLDrepeatLR_classA_rpt

MALRD1 LRP1 MFRP LDLR

3.98e-0549734IPR002172
DomainLDLa

MALRD1 LRP1 MFRP LDLR

3.98e-0549734SM00192
DomainThbs/COMP_coiled-coil

THBS3 THBS4

4.51e-053732IPR024665
DomainCOMP

THBS3 THBS4

4.51e-053732PF11598
DomainLaminin_G

SLIT2 THBS3 THBS4 FAT3

7.77e-0558734IPR001791
DomainPAS_fold_3

PER3 PER2 PER1

9.59e-0523733IPR013655
DomainPAS_3

PER3 PER2 PER1

9.59e-0523733PF08447
DomainPAS-assoc_C

PER3 PER2 PER1

1.09e-0424733IPR000700
DomainEGF

SLIT2 THBS4 MALRD1 LRP1 CUBN

1.34e-04126735PF00008
DomainPAC

PER3 PER2 PER1

1.40e-0426733IPR001610
DomainPAC

PER3 PER2 PER1

1.40e-0426733SM00086
DomainPAC

PER3 PER2 PER1

1.40e-0426733PS50113
DomainTSP_3

THBS3 THBS4

1.50e-045732PF02412
DomainPKNOX/Meis_N

MEIS3 MEIS1

1.50e-045732IPR032453
DomainTSP3

THBS3 THBS4

1.50e-045732PS51234
DomainTSP_CTER

THBS3 THBS4

1.50e-045732PS51236
Domain-

THBS3 THBS4

1.50e-0457324.10.1080.10
DomainThrombospondin_C

THBS3 THBS4

1.50e-045732IPR008859
DomainTSP_C

THBS3 THBS4

1.50e-045732PF05735
DomainThrombospondin_3_rpt

THBS3 THBS4

1.50e-045732IPR017897
DomainMeis_PKNOX_N

MEIS3 MEIS1

1.50e-045732PF16493
DomainThrombospondin_3-like_rpt

THBS3 THBS4

1.50e-045732IPR003367
DomainTSP_type-3_rpt

THBS3 THBS4

1.50e-045732IPR028974
DomainPAS

PER3 PER2 PER1

2.62e-0432733SM00091
DomainPreSET

SETDB1 EHMT1

3.12e-047732SM00468
DomainPre-SET

SETDB1 EHMT1

3.12e-047732PF05033
DomainPre-SET_dom

SETDB1 EHMT1

3.12e-047732IPR007728
DomainPRE_SET

SETDB1 EHMT1

3.12e-047732PS50867
DomainPAS

PER3 PER2 PER1

3.14e-0434733IPR000014
DomainPAS

PER3 PER2 PER1

3.14e-0434733PS50112
Domain-

SLIT2 THBS3 THBS4 FAT3

5.23e-04957342.60.120.200
DomainLdl_recept_b

LRP1 LDLR

1.33e-0314732PF00058
DomainLDLRB

LRP1 LDLR

1.33e-0314732PS51120
DomainLY

LRP1 LDLR

1.53e-0315732SM00135
DomainLDLR_classB_rpt

LRP1 LDLR

1.53e-0315732IPR000033
DomainConA-like_dom

SLIT2 THBS3 THBS4 MALRD1 FAT3

1.67e-03219735IPR013320
DomainSec7

ARFGEF3 IQSEC3

1.75e-0316732SM00222
DomainSEC7

ARFGEF3 IQSEC3

1.75e-0316732PS50190
DomainSec7_dom

ARFGEF3 IQSEC3

1.75e-0316732IPR000904
DomainHomeobox_KN

MEIS3 MEIS1

1.97e-0317732PF05920
DomainHomeobox_KN_domain

MEIS3 MEIS1

1.97e-0317732IPR008422
DomainTSPN

THBS3 THBS4

3.61e-0323732SM00210
DomaincEGF

FBN2 LRP1

4.61e-0326732IPR026823
DomaincEGF

FBN2 LRP1

4.61e-0326732PF12662
DomainhEGF

SLIT2 FBN2

5.33e-0328732PF12661
PathwayWP_MELATONIN_METABOLISM_AND_EFFECTS

ADRB1 PER3 PER2 PER1

1.24e-0537554M39418
PathwayKEGG_CIRCADIAN_RHYTHM_MAMMAL

PER3 PER2 PER1

1.56e-0513553M18009
Pubmed

Expression profiles of PERIOD1, 2, and 3 in peripheral blood mononuclear cells from older subjects.

PER3 PER2 PER1

1.09e-08378319013183
Pubmed

A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light.

PER3 PER2 PER1

1.09e-0837839428527
Pubmed

Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice.

PER3 PER2 PER1

1.09e-08378326781276
Pubmed

Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.

PER3 PER2 PER1

1.09e-0837839427249
Pubmed

Association between polymorphisms in period genes and bone density in postmenopausal Korean women.

PER3 PER2 PER1

1.09e-08378324678593
Pubmed

Photic entrainment of period mutant mice is predicted from their phase response curves.

PER3 PER2 PER1

1.09e-08378320826680
Pubmed

Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock.

PER3 PER2 PER1

1.09e-08378311395012
Pubmed

mPeriod2 Brdm1 and other single Period mutant mice have normal food anticipatory activity.

PER3 PER2 PER1

1.09e-08378329138421
Pubmed

A time memory engram embedded in a light-entrainable circadian clock.

PER3 PER2 PER1

1.09e-08378337951213
Pubmed

Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity.

PER3 PER2 PER1

1.09e-08378312032351
Pubmed

Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers.

PER3 PER2 PER1

1.09e-08378315790588
Pubmed

Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function.

PER3 PER2 PER1

1.09e-08378322331899
Pubmed

Aberrant expression of Per1, Per2 and Per3 and their prognostic relevance in non-small cell lung cancer.

PER3 PER2 PER1

1.09e-08378325550826
Pubmed

A light-independent oscillatory gene mPer3 in mouse SCN and OVLT.

PER3 PER2 PER1

1.09e-0837839707434
Pubmed

Intracellular calcium mobilization induces period genes via MAP kinase pathways in NIH3T3 cells.

PER3 PER2 PER1

1.09e-08378311959112
Pubmed

Comparing expression levels of PERIOD genes PER1, PER2 and PER3 in chronic insomnia patients and medical staff working in the night shift.

PER3 PER2 PER1

1.09e-08378332805476
Pubmed

Sleep rhythmicity and homeostasis in mice with targeted disruption of mPeriod genes.

PER3 PER2 PER1

1.09e-08378315031135
Pubmed

Nuclear export of mammalian PERIOD proteins.

PER3 PER2 PER1

1.09e-08378311591712
Pubmed

Period determination in the food-entrainable and methamphetamine-sensitive circadian oscillator(s).

PER3 PER2 PER1

1.09e-08378322891330
Pubmed

The role of phosphorylation and degradation of hPER protein oscillation in normal human fibroblasts.

PER3 PER2 PER1

1.09e-08378314712925
Pubmed

Period Family of Clock Genes as Novel Predictors of Survival in Human Cancer: A Systematic Review and Meta-Analysis.

PER3 PER2 PER1

1.09e-08378332849922
Pubmed

Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway.

PER3 PER2 PER1

1.09e-08378329269828
Pubmed

The complex relationship between the light-entrainable and methamphetamine-sensitive circadian oscillators: evidence from behavioral studies of Period-mutant mice.

PER3 PER2 PER1

1.09e-08378323869717
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SLIT2 SETDB1 TUT4 FBN2 KAT5 HMCN2 FAT3 BACH2 PER1 LRP1 EHMT1 C11orf16 LDLR AKAP8L BAHCC1

2.36e-081116781531753913
Pubmed

An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.

PER3 PER2 PER1

4.33e-08478311232563
Pubmed

Molecular analysis of mammalian timeless.

PER3 PER2 PER1

4.33e-0847839856466
Pubmed

Endotoxin Disrupts Circadian Rhythms in Macrophages via Reactive Oxygen Species.

PER3 PER2 PER1

4.33e-08478327168152
Pubmed

Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome.

PER3 PER2 PER1

4.33e-08478315800623
Pubmed

Regulation of clock genes.

PER3 PER2 PER1

4.33e-08478310487202
Pubmed

Cloning and characterization of rat casein kinase 1epsilon.

PER3 PER2 PER1

4.33e-08478310899319
Pubmed

The circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice.

PER3 PER2 PER1

4.33e-08478319587447
Pubmed

Expression of basic helix-loop-helix/PAS genes in the mouse suprachiasmatic nucleus.

PER3 PER2 PER1

4.33e-08478310077321
Pubmed

Comparison of β-adrenergic and glucocorticoid signaling on clock gene and osteoblast-related gene expressions in human osteoblast.

PER3 PER2 PER1

4.33e-08478322217103
Pubmed

Identification of a conserved family of Meis1-related homeobox genes.

MEIS3 MEIS1 MEIS3P1

4.33e-0847839049632
Pubmed

The ins and outs of circadian timekeeping.

PER3 PER2 PER1

4.33e-08478310508692
Pubmed

Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription.

PER3 PER2 PER1

1.08e-0757839856465
Pubmed

Disturbance of circadian gene expression in hepatocellular carcinoma.

PER3 PER2 PER1

1.08e-07578318444243
Pubmed

Intercellular coupling confers robustness against mutations in the SCN circadian clock network.

PER3 PER2 PER1

1.08e-07578317482552
Pubmed

Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells.

PER3 PER2 PER1

1.08e-07578311865049
Pubmed

Dimerization and nuclear entry of mPER proteins in mammalian cells.

PER3 PER2 PER1

1.08e-07578310837028
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NHSL1 PLEKHG1 TLNRD1 DACT1 SYNRG PER2 TMCC2 PER1 EHMT1 KDM3B ICE1 LDLR REXO1 BAHCC1

1.52e-071105781435748872
Pubmed

A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock.

PER3 PER2 PER1

2.16e-0767839989497
Pubmed

Molecular bases for circadian clocks.

PER3 PER2 PER1

2.16e-0767839988221
Pubmed

Macromolecular Assemblies of the Mammalian Circadian Clock.

PER3 PER2 PER1

2.16e-07678328886335
Pubmed

Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight, and type 2 diabetic.

PER3 PER2 PER1

2.16e-07678321411511
Pubmed

The role of polymorphisms in circadian pathway genes in breast tumorigenesis.

PER3 PER2 PER1

2.16e-07678320978934
Pubmed

Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts.

PER3 PER2 PER1

2.16e-07678314750904
Pubmed

Matrix metalloproteinase 2 and 9 dysfunction underlie vascular stiffness in circadian clock mutant mice.

PER3 PER2 PER1

2.16e-07678320829506
Pubmed

mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop.

PER3 PER2 PER1

2.16e-07678310428031
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PLEKHH1 ARFGEF3 PLEKHG1 SETDB1 ASXL1 IQSEC3 TCF20 PER2 USP15

3.37e-0740778912693553
Pubmed

Analysis of the molecular pathophysiology of sleep disorders relevant to a disturbed biological clock.

PER3 PER2 PER1

3.77e-07778323546644
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARFGEF3 NHSL1 PLEKHG1 SYNRG ZNF106 MTMR4 TCF20 SASH1 ERCC6L KDM3B LAMC1 CARD8

4.77e-07861781236931259
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ZNF106 SETDB1 RIOK1 MTMR4 TUT4 TCF20 ERCC6L KDM3B SRPRA ICE1 USP15

7.30e-07733781134672954
Pubmed

Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock.

PER3 PER2 PER1

9.03e-07978314701732
Pubmed

Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.

PER3 PER2 PER1

9.03e-07978331875550
Pubmed

Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder.

PER3 PER2 PER1

1.29e-061078316528748
Pubmed

Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study.

PER3 PER2 PER1

1.29e-061078319934327
Pubmed

Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus.

PER3 PER2 PER1

4.84e-061578312024206
Pubmed

Dopamine adjusts the circadian gene expression of Per2 and Per3 in human dermal fibroblasts from ADHD patients.

PER3 PER2

4.97e-06278234275001
Pubmed

Circadian rhythm disruption impairs tissue homeostasis and exacerbates chronic inflammation in the intestine.

PER2 PER1

4.97e-06278228710114
Pubmed

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

INSR LDLR

4.97e-06278219273907
Pubmed

Cardiac Per2 functions as novel link between fatty acid metabolism and myocardial inflammation during ischemia and reperfusion injury of the heart.

PER2 PER1

4.97e-06278223977055
Pubmed

De novo synthesis of PERIOD initiates circadian oscillation in cultured mouse suprachiasmatic nucleus after prolonged inhibition of protein synthesis by cycloheximide.

PER2 PER1

4.97e-06278222236088
Pubmed

Expression of circadian Per1 and Per2 genes in the liver and breast tumor tissues of HER2/neu transgenic mice of different age.

PER2 PER1

4.97e-06278222238756
Pubmed

Masking responses to light in period mutant mice.

PER2 PER1

4.97e-06278221793695
Pubmed

Alterations in the expression of Per1 and Per2 induced by Aβ31-35 in the suprachiasmatic nucleus, hippocampus, and heart of C57BL/6 mouse.

PER2 PER1

4.97e-06278227021954
Pubmed

Prognostic relevance of Period1 (Per1) and Period2 (Per2) expression in human gastric cancer.

PER2 PER1

4.97e-06278224551282
Pubmed

PERIOD1 (PER1) has anti-apoptotic effects, and PER3 has pro-apoptotic effects during cisplatin (CDDP) treatment in human gingival cancer CA9-22 cells.

PER3 PER1

4.97e-06278221459569
Pubmed

LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.

LRP1 LDLR

4.97e-06278217505534
Pubmed

Low density lipoprotein receptor-related protein polymorphisms are not risk factors for venous thromboembolism.

LRP1 LDLR

4.97e-06278217889283
Pubmed

Constant darkness is a circadian metabolic signal in mammals.

PER2 PER1

4.97e-06278216421573
Pubmed

Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.

PER2 PER1

4.97e-06278211389837
Pubmed

Circadian regulation of central ethanol sensitivity by the mPer2 gene.

PER2 PER1

4.97e-06278219523042
Pubmed

Cocaine sensitization and reward are under the influence of circadian genes and rhythm.

PER2 PER1

4.97e-06278212084940
Pubmed

Differential daily expression of Per1 and Per2 mRNA in the suprachiasmatic nucleus of fetal and early postnatal mice.

PER2 PER1

4.97e-06278211207804
Pubmed

Resetting the brain clock: time course and localization of mPER1 and mPER2 protein expression in suprachiasmatic nuclei during phase shifts.

PER2 PER1

4.97e-06278215009158
Pubmed

Insights into structure and activity relationship of clinically mutated PER1 and PER2 class A β-lactamase enzymes.

PER2 PER1

4.97e-06278235475497
Pubmed

Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver.

PER2 PER1

4.97e-06278220370466
Pubmed

cAMP-dependent signaling as a core component of the mammalian circadian pacemaker.

PER2 PER1

4.97e-06278218487196
Pubmed

174delG mutation in mouse MFRP causes photoreceptor degeneration and RPE atrophy.

PER3 MFRP

4.97e-06278221810984
Pubmed

Decoupling PER phosphorylation, stability and rhythmic expression from circadian clock function by abolishing PER-CK1 interaction.

PER2 PER1

4.97e-06278235810166
Pubmed

Cardiac atrial circadian rhythms in PERIOD2::LUCIFERASE and per1:luc mice: amplitude and phase responses to glucocorticoid signaling and medium treatment.

PER2 PER1

4.97e-06278223110090
Pubmed

Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice.

LRP1 LDLR

4.97e-06278211971949
Pubmed

Circadian Modulation of Neurons and Astrocytes Controls Synaptic Plasticity in Hippocampal Area CA1.

PER2 PER1

4.97e-06278233053337
Pubmed

Possible Association of PER2/PER3 Variable Number Tandem Repeat Polymorphism Variants with Susceptibility and Clinical Characteristics in Pancreatic Cancer.

PER3 PER2

4.97e-06278233393850
Pubmed

Presence of multiple peripheral circadian oscillators in the tissues controlling voiding function in mice.

PER2 PER1

4.97e-06278224603368
Pubmed

The circadian clock protects against ionizing radiation-induced cardiotoxicity.

PER2 PER1

4.97e-06278231919902
Pubmed

Period gene expression in mouse endocrine tissues.

PER2 PER1

4.97e-06278212775559
Pubmed

Circadian time-dependent tumor suppressor function of period genes.

PER2 PER1

4.97e-06278219926612
Pubmed

Forebrain oscillators ticking with different clock hands.

PER2 PER1

4.97e-06278217996461
Pubmed

Circadian gene expression is resilient to large fluctuations in overall transcription rates.

PER2 PER1

4.97e-06278219078963
Pubmed

Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.

INSR LDLR

4.97e-06278216581003
Pubmed

The circadian clock and tumor suppression by mammalian period genes.

PER2 PER1

4.97e-06278215817328
Pubmed

Low reproductive success in Per1 and Per2 mutant mouse females due to accelerated ageing?

PER2 PER1

4.97e-06278218367514
Pubmed

Temporal expression profiles of ceramide and ceramide-related genes in wild-type and mPer1/mPer2 double knockout mice.

PER2 PER1

4.97e-06278221773940
Pubmed

Homeostatic sleep regulation is preserved in mPer1 and mPer2 mutant mice.

PER2 PER1

4.97e-06278212383239
Pubmed

Segregation of expression of mPeriod gene homologs in neurons and glia: possible divergent roles of mPeriod1 and mPeriod2 in the brain.

PER2 PER1

4.97e-06278219477955
Pubmed

Mice lacking Period 1 and Period 2 circadian clock genes exhibit blue cone photoreceptor defects.

PER2 PER1

4.97e-06278223351077
Pubmed

Circadian clock genes Per1 and Per2 regulate the response of metabolism-associated transcripts to sleep disruption.

PER2 PER1

4.97e-06278223285241
Pubmed

Core circadian clock genes Per1 and Per2 regulate the rhythm in photoreceptor outer segment phagocytosis.

PER2 PER1

4.97e-06278234160105
InteractionPER3 interactions

PER3 PER2 FAT3 PER1

1.87e-0624764int:PER3
InteractionCOL20A1 interactions

FAT3 REL MEIS1 USP47

3.07e-0627764int:COL20A1
Cytoband11p15.3

C11orf16 USP47

5.86e-042178211p15.3
Cytoband10p12.31

MALRD1 CUBN

6.44e-042278210p12.31
Cytoband6q23.3

ARFGEF3 NHSL1

1.05e-03287826q23.3
GeneFamilyTALE class homeoboxes and pseudogenes

MEIS3P2 MEIS3 MEIS1 MEIS3P1

4.81e-0726454526
GeneFamilyLow density lipoprotein receptors

LRP1 LDLR

4.64e-0413452634
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETDB1 EHMT1

3.23e-0334452487
CoexpressionNABA_ECM_GLYCOPROTEINS

SLIT2 THBS3 THBS4 FBN2 HMCN2 LAMC1

2.30e-05191786MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

SLIT2 THBS3 THBS4 FBN2 HMCN2 LAMC1

2.66e-05196786M3008
CoexpressionGSE13306_TREG_VS_TCONV_SPLEEN_UP

ARFGEF3 ASXL1 THBS4 PER3 BACH2 LAMC1

2.98e-05200786M3224
CoexpressionGSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_DN

SYNRG FOXQ1 PER1 LRP1 REL C11orf16

2.98e-05200786M9067
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SLIT2 SETDB1 ASXL1 TUT4 SASH1 ATAD2B ARHGAP12 KDM3B LAMC1 USP15 LDLR

4.47e-058567811M4500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200

SLIT2 DACT1 CLCA1 GUCY1A1 FAT3 LRP1

4.85e-0782766gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

SLIT2 DACT1 FBN2 CLCA1 GUCY1A1 FAT3 LRP1 MEIS1

7.61e-07207768gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000

SLIT2 DACT1 TUT4 FBN2 CLCA1 GUCY1A1 FAT3 LRP1 MEIS1

4.79e-06354769gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

SLIT2 FBN2 CLCA1 GUCY1A1 LRP1 MEIS1

5.00e-06122766gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_200

FBN2 CLCA1 GUCY1A1 MEIS1

5.73e-0633764gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

SLIT2 DACT1 CLCA1 GUCY1A1 FAT3 LRP1

1.40e-05146766gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500

SLIT2 FBN2 CLCA1 GUCY1A1 LRP1 MEIS1

1.40e-05146766gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

SLIT2 DACT1 FBN2 CLCA1 GUCY1A1 FAT3 LRP1 MEIS1

1.50e-05310768gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

SLIT2 DACT1 FBN2 CLCA1 GUCY1A1 FAT3 LRP1 CNGA1 MEIS1

1.81e-05418769gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

SLIT2 DACT1 CLCA1 GUCY1A1 FAT3 LRP1

2.04e-05156766gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

SLIT2 DACT1 FBN2 CLCA1 GUCY1A1 FAT3 LRP1 MEIS1

2.73e-05337768gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

SLIT2 DACT1 CLCA1 GUCY1A1 FAT3 LRP1

2.80e-05165766gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

SLIT2 DACT1 FBN2 CLCA1 GUCY1A1 FAT3 LRP1 MEIS1

4.03e-05356768gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500

CLCA1 GUCY1A1 FAT3 LRP1

4.18e-0554764gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k2_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

SLIT2 FBN2 CLCA1 GUCY1A1 FAT3 LRP1 MEIS1

4.57e-05265767gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

SLIT2 DACT1 CLCA1 GUCY1A1 FAT3 LRP1 CNGA1 MEIS1

4.72e-05364768gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

SLIT2 DACT1 CLCA1 GUCY1A1 FAT3 LRP1

4.85e-05182766gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500

DACT1 DDIT4 THBS3 FBN2 CSRNP3 MEIS1

5.81e-05188766gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_200

DACT1 CLCA1 GUCY1A1 FAT3

5.94e-0559764gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

SLIT2 CLCA1 GUCY1A1 FAT3 LRP1

8.63e-05125765gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

SLIT2 DACT1 TUT4 FBN2 CLCA1 ERCC6L GUCY1A1 FAT3 LRP1 CNGA1 MEIS1

8.66e-057687611gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

DACT1 CLCA1 GUCY1A1 FAT3 LRP1

1.04e-04130765gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasMESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst-Confounder_removed-fold2.0_adjp0.05

PLEKHG1 SETDB1 MTMR4 TUT4 PER3 FAT3 PER1 BBS1 ZNF770 EML1 AKAP8L MEIS1 CARD8 BAHCC1

1.19e-0412457614PCBC_ratio_MESO-30 amniotic fluid MSC_vs_MESO-30 blastocyst_cfr-2X-p05
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500

SLIT2 SETDB1 DDIT4 CLCA1 ERCC6L INSR LAMC1 ZNF770

1.30e-04421768gudmap_developingLowerUrinaryTract_e14.5_ bladder_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500

SLIT2 DACT1 FBN2 CLCA1 GUCY1A1 FAT3 LRP1 MEIS1

1.34e-04423768gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

SLIT2 DACT1 FBN2 CLCA1 CSRNP3 ERCC6L GUCY1A1 FAT3 LRP1 CNGA1 MEIS1

1.66e-048277611gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

SLIT2 DACT1 THBS3 THBS4 SASH1 LRP1 LAMC1 MEIS1

1.67e-04437768GSM777046_500
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#2

GUCY1A1 SUCNR1 MEIS1 BAHCC1

1.77e-0478764ratio_EB_vs_SC_500_K2
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

SLIT2 DACT1 CLCA1 GUCY1A1 FAT3 LRP1 MEIS1

3.10e-04361767gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100

CLCA1 GUCY1A1 FAT3

3.14e-0437763gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

SLIT2 CLCA1 GUCY1A1 FAT3 LRP1

3.43e-04168765gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_500

SLIT2 FAT3 BCORL1 LRP1 MEIS1

4.13e-04175765gudmap_developingGonad_e14.5_ epididymis_500_k4
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_200

CLCA1 GUCY1A1 LRP1

4.58e-0442763gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#2_top-relative-expression-ranked_200

CLCA1 GUCY1A1 MEIS1

4.58e-0442763gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k2_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

DACT1 SETDB1 THBS4 CLCA1 FOXQ1 GUCY1A1 FAT3 BACH2 INSR LAMC1

5.81e-048067610gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500

SETDB1 CLCA1 FOXQ1 CSRNP3 GUCY1A1 FAT3 INSR

6.42e-04408767DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

SLIT2 DACT1 TUT4 FBN2 CLCA1 CSRNP3 GUCY1A1 FAT3 LRP1 MEIS1

7.36e-048317610gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_100

CLCA1 GUCY1A1

8.15e-0412762gudmap_dev gonad_e11.5_F_GonMes_Sma_k1_100
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

SLIT2 DACT1 CLCA1 GUCY1A1 LRP1 MEIS1

8.70e-04311766gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000

SETDB1 GUCY1A1 FAT3 BACH2 INSR LAMC1

8.85e-04312766gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
ToppCellCOPD-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

PLEKHG1 ADRB1 SASH1 EML1 CLEC4M MEIS1

7.88e-0718178661608123959483ff60f07d8467996853c4371b6a
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 THBS4 GUCY1A1 LRP1 LAMC1 MEIS1

8.14e-071827863dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 DACT1 ZNF106 FBN2 HMCN2 GUCY1A1

1.25e-06196786308fa54385ca34e9e590967d4553b84aad96c92f
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PLEKHG1 SASH1 INSR EML1 CLEC4M MEIS1

1.25e-06196786e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 SASH1 EML1 CLEC4M MEIS1

1.29e-0619778681718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 DACT1 ZNF106 FBN2 HMCN2 GUCY1A1

1.37e-06199786eeb7d370d4dfacf705306c72ccc4919ddefacff1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 IQSEC3 INSR PEPD CUBN

1.26e-05171785f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

1.26e-05171785bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 FAT3 INSR LDLR BAHCC1

1.41e-05175785dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHH1 PER2 ATP10B LDLR MEIS1

1.57e-051797856e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 IQSEC3 INSR PEPD CUBN

1.62e-051807851363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

1.80e-051847855f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

1.84e-05185785a28187c2fd23564314b35759479ff2ca21f61485
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

SLIT2 HMCN2 BACH2 LRP1 LAMC1

1.94e-051877854ea486991f66c29728d127171a07b81404ec0b78
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

PLEKHG1 SASH1 BACH2 EML1 MEIS1

1.94e-05187785f3548817f2fded5978137bb252cb628ac199e4f6
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

1.94e-0518778554d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

1.99e-05188785e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D122|Adult / Lineage, Cell type, age group and donor

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

1.99e-0518878502a62888e9db29d20133eeca1686d302545a39c9
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.04e-05189785b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 DACT1 LRP1 LAMC1 MEIS3

2.04e-05189785d531399749409d614adca13d181830c6e3287508
ToppCellIPF-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.04e-05189785ea3aa3ef38f1d405bb527ae383cd12c551a3dd6f
ToppCellIPF-Endothelial-VE_Capillary_A|IPF / Disease state, Lineage and Cell class

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.10e-05190785b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.15e-05191785c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellControl-Endothelial-VE_Capillary_B|Control / Disease state, Lineage and Cell class

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.15e-05191785322237793a1278bafb14e63cab688b353e352dcc
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ADRB1 SASH1 GUCY1A1 EML1

2.20e-05192785c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.20e-051927851e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DACT1 THBS3 HMCN2 LRP1 LAMC1

2.20e-0519278529bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DACT1 THBS3 HMCN2 LRP1 LAMC1

2.20e-05192785cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 DACT1 HMCN2 GUCY1A1 MEIS1

2.20e-0519278520ede290e01ad574afd122d72b59dbc52c595fad
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.26e-05193785f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 DACT1 HMCN2 GUCY1A1 MEIS1

2.26e-051937857cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ASXL1 PER2 PER1 REL LDLR

2.26e-05193785dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)|Adult / Lineage, Cell type, age group and donor

PLEKHG1 SASH1 EML1 CLEC4M MEIS1

2.26e-0519378539c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCellLA|World / Chamber and Cluster_Paper

SLIT2 HMCN2 BACH2 LRP1 LAMC1

2.26e-05193785d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ADRB1 SASH1 GUCY1A1 EML1

2.26e-05193785a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

SLIT2 FAT3 BACH2 LAMC1 MEIS1

2.26e-05193785acad568621ed677031797b8c2e34dafea798d681
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.26e-05193785ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

DDIT4 TUT4 PER1 REL USP15

2.26e-051937857256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLIT2 HMCN2 PER1 MEIS3 MEIS1

2.37e-05195785ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

SLIT2 HMCN2 BACH2 LRP1 LAMC1

2.37e-05195785a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

SLIT2 FAT3 BACH2 LAMC1 MEIS1

2.37e-0519578561c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

SLIT2 GUCY1A1 FAT3 LAMC1 MEIS1

2.37e-05195785603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCelldroplet-Limb_Muscle-MUSCLE-1m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 PER3 PER2 PER1 LAMC1

2.37e-05195785fee9d13f48149cd5f921cfe4b8b3053cf6a6dbd2
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

SLIT2 FAT3 BACH2 LAMC1 MEIS1

2.37e-05195785aa0add081881d349099d12efca5cdee098038d4e
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.43e-0519678549cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.43e-051967854ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PLEKHG1 DDIT4 BACH2 PER1 REL

2.49e-05197785fd5fdc5289d681d59ff22d72e4de6e74c6c7aac6
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLIT2 GUCY1A1 FAT3 LRP1 MEIS1

2.49e-0519778573a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLIT2 FAT3 LRP1 LAMC1 MEIS1

2.55e-051987853ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

PER1 LRP1 REL USP15 LDLR

2.55e-0519878561ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.55e-05198785a1ccbf0e653b2dd665c2254920eb9b37243cc0bd
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 DACT1 HMCN2 GUCY1A1 MEIS1

2.55e-0519878512cd9f0bbad8dce5199ebfed1c4a8080710ca055
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.61e-05199785dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLIT2 LRP1 MEIS3 LDLR MEIS1

2.61e-051997858b86c69aaf60feff53aa782559cfece7342a23de
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLEKHG1 INSR LAMC1 CUBN LDLR

2.61e-0519978563c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

ARFGEF3 CSRNP3 FAT3 BACH2 EML1

2.61e-05199785058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellmLN-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

DDIT4 PER1 LRP1 SRPRA USP15

2.68e-05200785e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN2 GUCY1A1 LRP1 LAMC1 MEIS1

2.68e-052007853dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLIT2 FAT3 BACH2 LRP1 MEIS1

2.68e-05200785cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLIT2 FAT3 BACH2 LRP1 MEIS1

2.68e-05200785311fab076f2ceb258e3970eb21e39344b894042a
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLIT2 FAT3 BACH2 LRP1 MEIS1

2.68e-0520078534f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 SASH1 EML1 MEIS1

2.68e-05200785105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital|World / Primary Cells by Cluster

ARFGEF3 NHSL1 DACT1 FAT3 EML1

2.68e-052007856bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19|World / Primary Cells by Cluster

ARFGEF3 NHSL1 DACT1 FAT3 EML1

2.68e-05200785c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 PCARE ATP10B CNGA1

1.10e-04141784091b5b72811db5fca2314f4a79d467566920e257
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TUT4 TCF20 BACH2 ICE1

1.75e-041597842881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellHealthy_Control-Lymphoid-B-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PLEKHH1 HMCN2 BACH2 SGO1

1.92e-04163784d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCellHealthy_Control-Lymphoid-B|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PLEKHH1 HMCN2 BACH2 SGO1

1.92e-041637840f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

DACT1 FBN2 HMCN2 BACH2

2.01e-041657843d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

MALRD1 FAT3 MEIS1 BAHCC1

2.01e-041657847b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SLIT2 MALRD1 FAT3 LRP1

2.06e-0416678465dafed953b01a9830b54309af75c7a561e88336
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6L BACH2 KDM3B REL

2.06e-041667846a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6L BACH2 KDM3B REL

2.06e-041667848d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

ZNF106 ADRB1 TMCC2 MEIS1

2.06e-041667844b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

PLEKHG1 SASH1 EML1 MEIS1

2.11e-041677845af9127bae05768a5164d5708a4ad37edca99324
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

GUCY1A1 FAT3 MEIS1 BAHCC1

2.11e-04167784cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDIT4 PEPD REL SUCNR1

2.16e-041687842c996d09b6a8ccd3c708146eca310b02eafff425
ToppCelldroplet-Lung-nan-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDIT4 FOXQ1 WFIKKN2 CNGA1

2.21e-04169784da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCelldroplet-Lung-nan-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDIT4 FOXQ1 WFIKKN2 CNGA1

2.21e-04169784a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXQ1 CSRNP3 FAT3 CUBN

2.21e-0416978412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXQ1 ERCC6L FAT3 C11orf16

2.36e-04172784c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 LRP1 LAMC1 MEIS3

2.36e-04172784e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TUT4 BACH2 ATAD2B REL

2.41e-04173784694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IQSEC3 GUCY1A1 ATP10B MEIS1

2.41e-0417378434357f0e22c4b6d84582492c82c1ea733ca8477d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CSRNP3 LRP1 MEIS3 MEIS1

2.58e-041767849bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL1 ADRB1 SASH1 ZNF770

2.58e-041767847292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CSRNP3 LRP1 MEIS3 MEIS1

2.58e-041767843f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLIT2 FBN2 SASH1 CNGA1

2.58e-04176784d09e28606e2a6ed1f660898316765ca215085c18
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL1 ADRB1 SASH1 ZNF770

2.58e-0417678488ca2f83d8301633232735f39b0683efe49d0b86
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 SASH1 EML1 MEIS1

2.81e-04180784b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLEKHG1 TLNRD1 ADRB1 SASH1

2.81e-04180784d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

R3HCC1L TCF20 SASH1 SENP6

2.87e-04181784b193f3606554adc55c5906219d114288bb1f978a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DACT1 FAT3 LRP1 MEIS3

2.87e-04181784c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PLEKHG1 ADRB1 SASH1 EML1

2.87e-04181784c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN2 SASH1 FAT3 ATP10B

2.87e-041817846956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLIT2 FAT3 LAMC1 MEIS1

2.87e-041817849ede19228ba5c0668a9c06c915510b95585216ef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DACT1 FAT3 LRP1 MEIS3

2.87e-04181784c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DACT1 FBN2 FOXQ1 MEIS1

2.93e-04182784812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

ADRB1 SASH1 EML1 MEIS1

2.93e-041827848b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF106 TUT4 BACH2 REL

2.93e-04182784eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
Drugcobalt(II) chloride hexahydrate; Up 200; 100uM; MCF7; HG-U133A

SLIT2 DDIT4 THBS4 TUT4 CLCA1 SASH1 LDLR BAHCC1

3.35e-07199768454_UP
DrugTolazamide [1156-19-0]; Up 200; 12.8uM; PC3; HT_HG-U133A

SETDB1 THBS3 KAT5 PER3 PER2 CSRNP3 C11orf16

4.03e-061957674003_UP
DrugOrlistat, 5

DDIT4 PER2 PER1 EHMT1 LDLR

1.02e-0586765CID000004599
Diseaserestless legs syndrome (implicated_via_orthology)

MEIS3P2 MEIS3 MEIS1 MEIS3P1

2.82e-098764DOID:0050425 (implicated_via_orthology)
Diseaseleukemia (implicated_via_orthology)

MEIS3P2 MEIS3 MEIS1 MEIS3P1

1.53e-0719764DOID:1240 (implicated_via_orthology)
Diseasecortical thickness

NHSL1 PLEKHG1 SLIT2 DACT1 ZNF106 THBS3 FBN2 MALRD1 FAT3 ARHGAP12 LRP1 LAMC1 EML1 USP15

8.43e-0711137614EFO_0004840
DiseaseMyeloid Leukemia, Chronic

ASXL1 PER3 PER2 PER1

9.19e-0729764C0023473
DiseaseAgents acting on the renin-angiotensin system use measurement

PLEKHG1 ADRB1 FBN2 KAT5 GUCY1A1 INSR LDLR REXO1

2.45e-06335768EFO_0009931
Diseasemean arterial pressure

PLEKHG1 THBS3 ADRB1 FBN2 TCF20 GUCY1A1 INSR REXO1 BAHCC1

5.49e-06499769EFO_0006340
Diseasemean arterial pressure, alcohol drinking

PLEKHG1 ADRB1 GUCY1A1 INSR ICE1

5.59e-0698765EFO_0004329, EFO_0006340
DiseaseBeta blocking agent use measurement

PLEKHG1 ADRB1 FBN2 GUCY1A1 INSR

1.17e-05114765EFO_0009929
Diseasediastolic blood pressure, alcohol drinking

PLEKHG1 ADRB1 KAT5 GUCY1A1 INSR

1.38e-05118765EFO_0004329, EFO_0006336
DiseaseCalcium channel blocker use measurement

PLEKHG1 THBS3 ADRB1 FBN2 GUCY1A1 INSR

1.89e-05213766EFO_0009930
DiseaseAdvanced Sleep-Phase Syndrome, Familial

PER3 PER2

1.96e-053762C1858496
Diseasesystolic blood pressure, alcohol drinking

PLEKHG1 ADRB1 KAT5 GUCY1A1 INSR

2.05e-05128765EFO_0004329, EFO_0006335
Diseasecardiovascular disease

PLEKHG1 ADRB1 FBN2 GUCY1A1 INSR LDLR REXO1 BAHCC1

2.34e-05457768EFO_0000319
Diseaseadvanced sleep phase syndrome (is_implicated_in)

PER3 PER2

3.92e-054762DOID:0050628 (is_implicated_in)
Diseasepulse pressure measurement

PLEKHG1 FBN2 MALRD1 GUCY1A1 FAT3 ATAD2B ARHGAP12 INSR PEPD LRP1 EML1 SRFBP1 MEIS1

5.17e-0513927613EFO_0005763
Diseasesmoking status measurement, systolic blood pressure

PLEKHG1 ADRB1 KAT5 GUCY1A1 INSR

5.29e-05156765EFO_0006335, EFO_0006527
Diseasesmoking status measurement, diastolic blood pressure

PLEKHG1 ADRB1 KAT5 GUCY1A1 INSR

5.79e-05159765EFO_0006336, EFO_0006527
DiseaseDiuretic use measurement

PLEKHG1 ADRB1 FBN2 GUCY1A1 INSR

7.73e-05169765EFO_0009928
Diseasecolorectal cancer, hormone replacement therapy

TUT4 SASH1 INSR USP47

8.04e-0588764EFO_0003961, MONDO_0005575
Diseasebrain measurement, neuroimaging measurement

NHSL1 SLIT2 DACT1 FBN2 FAT3 LAMC1 EML1 BAHCC1

8.59e-05550768EFO_0004346, EFO_0004464
Diseaseneuroimaging measurement

NHSL1 PLEKHG1 SLIT2 DACT1 ZNF106 FBN2 FAT3 ARHGAP12 LAMC1 EML1 BAHCC1

8.90e-0510697611EFO_0004346
Diseasebreast cancer (is_marker_for)

TUT4 KAT5 INSR KDM3B REL

1.18e-04185765DOID:1612 (is_marker_for)
Diseasespontaneous preterm birth

NHSL1 SLIT2 GUCY1A1 MEIS1

1.37e-04101764EFO_0006917
Diseasemyocardial infarction

PLEKHG1 SASH1 GUCY1A1 LAMC1 SRFBP1 LDLR

2.90e-04350766EFO_0000612
Diseasemean arterial pressure, alcohol consumption measurement

PLEKHG1 ADRB1 GUCY1A1

3.31e-0452763EFO_0006340, EFO_0007878
Diseasediastolic blood pressure, alcohol consumption measurement

PLEKHG1 ADRB1 GUCY1A1

3.71e-0454763EFO_0006336, EFO_0007878
Diseaseessential hypertension, age at diagnosis

GUCY1A1 REXO1 BAHCC1

4.13e-0456763EFO_0004918, MONDO_0001134
DiseaseWithdrawal Symptoms

PER3 PER2 PER1

4.58e-0458763C0087169
DiseaseDrug Withdrawal Symptoms

PER3 PER2 PER1

4.58e-0458763C0086189
DiseaseSubstance Withdrawal Syndrome

PER3 PER2 PER1

4.58e-0458763C0038587
Diseasebrain connectivity measurement

NHSL1 PLEKHG1 SLIT2 DACT1 FAT3 EML1

5.88e-04400766EFO_0005210
Diseasecortical surface area measurement

NHSL1 PLEKHG1 SLIT2 DACT1 ZNF106 FBN2 FAT3 ATAD2B ARHGAP12 LAMC1 EML1

6.38e-0413457611EFO_0010736
DiseaseAbnormal behavior

BCORL1 KDM3B

7.67e-0416762C0233514
Diseasecoronary artery disease

PLEKHG1 FBN2 MALRD1 R3HCC1L GUCY1A1 LRP1 LAMC1 EML1 SRFBP1 LDLR

9.57e-0411947610EFO_0001645
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

ADRB1 KAT5 INSR PEPD LDLR

1.19e-03307765EFO_0004612, EFO_0020946
Diseasenose morphology measurement, mouth morphology measurement

MEIS3 MEIS3P1

1.33e-0321762EFO_0007843, EFO_0007955
DiseaseMalignant neoplasm of breast

THBS3 FOXQ1 PER3 PER2 BCORL1 PER1 EHMT1 CUBN MEIS1

1.74e-031074769C0006142
Diseasediabetes mellitus (implicated_via_orthology)

INSR LRP1

2.04e-0326762DOID:9351 (implicated_via_orthology)
Diseasehypertension, COVID-19

PLEKHG1 GUCY1A1

2.20e-0327762EFO_0000537, MONDO_0100096
Diseasecholesteryl ester 14:0 measurement

LDLR CARD8

2.20e-0327762EFO_0010340
DiseaseColorectal Carcinoma

DACT1 FBN2 CSRNP3 PER1 LRP1 LAMC1 CUBN

2.21e-03702767C0009402
DiseaseDisorder of eye

BBS1 PCARE MFRP CNGA1

2.22e-03212764C0015397
Diseaseobsolete_red blood cell distribution width

PLEKHG1 ASXL1 FBN2 KAT5 ATAD2B TMCC2 INSR PEPD REXO1 USP47

2.34e-0313477610EFO_0005192
Diseaseanterior thigh muscle fat infiltration measurement

HMCN2 PEPD

2.37e-0328762EFO_0020936
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

ZNF106 TCF20 LDLR

2.41e-03103763EFO_0008595, EFO_0020944
DiseaseRetinitis Pigmentosa

BBS1 PCARE CNGA1

2.48e-03104763C0035334
Diseasehormone measurement, thyroid stimulating hormone measurement

SASH1 INSR

2.54e-0329762EFO_0004730, EFO_0004748
DiseaseBilateral Wilms Tumor

ASXL1 BCORL1

2.54e-0329762C2930471

Protein segments in the cluster

PeptideGeneStartEntry
CNGGAAADSDSSLDE

ADRB1

451

P08588
CEQSYGTNSSDESGS

BACH2

581

Q9BYV9
ASQEAGSGYDSEDCE

BAHCC1

1646

Q9P281
EESTTGDCQHFGSQE

BCORL1

36

Q5H9F3
CGSNEASTVSGENDV

ASXL1

111

Q8IXJ9
DSCSGDSSAQLSSGE

ATP10B

1411

O94823
CSDNSDSDNDEGTEG

AKAP8L

296

Q9ULX6
GNDTEDFSNPSACSD

R3HCC1L

431

Q7Z5L2
NTDSGSVCREASFDG

PEPD

151

P12955
VAGGDVCSSESFNED

MEIS1

106

O00470
GFANCADGSDETNCS

MFRP

281

Q9BY79
ADGSDETNCSAKFSG

MFRP

286

Q9BY79
DSGDYECQATNEVGS

HMCN2

1316

Q8NDA2
GDNDCGNSEDESNAT

LRP1

916

Q07954
NCLNGEASTDSFEGI

ATAD2B

1266

Q9ULI0
NCLGTDEDSQDSSDG

KAT5

191

Q92993
EEDGSSFCSGVTDSS

CSRNP3

346

Q8WYN3
ETNAAGSSSEACDFL

NHSL1

1326

Q5SYE7
CEEAQGGAKASSSQD

PER1

1251

O15534
NCSTGRDSQGSDCDD

PER2

46

O15055
NEDSADGAATSCGQV

PER3

1181

P56645
SFGCSSAQEAQKDTD

KDM3B

506

Q7LBC6
GGDVCSSDSFNEDIA

MEIS3

96

Q99687
NVTEFDGQDACGSNS

INSR

541

P06213
EDSCAEAAASGAADG

IQSEC3

551

Q9UPP2
SLSTGNNDTSEACDA

MTMR4

271

Q9NYA4
TSFSQEQSCDSAGEG

ARHGAP12

191

Q8IWW6
GGDVCSSDSFNEDNT

MEIS3P2

96

A8K0S8
DNCGDNTDENECGSS

MALRD1

1506

Q5VYJ5
DSENANLAGTFCGST

CUBN

3226

O60494
SEAFSCSEGSEQQDA

ICE1

1111

Q9Y2F5
TNCFGDSESSVSEGE

DACT1

751

Q9NYF0
SSDCESLDSSNSGFG

DDIT4

51

Q9NX09
DFGNQGSTVESLCDD

ARFGEF3

191

Q5TH69
GTSSSDVSANCGFDD

FAT3

4511

Q8TDW7
EQESSEGQDSGDICS

CARD8

121

Q9Y2G2
VCSSSDTGLFTNDEG

GPATCH2L

226

Q9NWQ4
TGGDEQQALCTDEFS

LAMC1

196

P11047
SNGGTNLCAVDDSND

EML1

336

O00423
NEGFQSSSSGTECLD

FBN2

2366

P35556
SSDSDACGAESNEAN

BBS1

6

Q8NFJ9
SSLGFESESGESEGC

C4orf54

301

D6RIA3
DGETNGSCENSDASS

EHMT1

51

Q9H9B1
AEQGDDEFTDVCNSG

ERCC6L

71

Q2NKX8
GDDSLGSDGDCAANS

FOXQ1

36

Q9C009
CSEDSGIGADNESVQ

PCARE

346

A6NGG8
RGGDVCSSDSFNEDN

MEIS3P1

11

A6NDR6
IGSSECSDTDSEEQG

RIOK1

501

Q9BRS2
DNVDGHSSSEDAGAC

REXO1

1191

Q8N1G1
DDECSSASASSAGAG

TMCC2

476

O75069
GASQETPNECSDDFG

SYNRG

1011

Q9UMZ2
NNESEVSLCESSGSG

SGO1

361

Q5FBB7
SCNSVSEGGFADSDS

SETDB1

986

Q15047
NNSGNEDCAEFSGSG

CLEC4M

361

Q9H2X3
TDGEDNTISGCFNEV

CLCA1

411

A8K7I4
ENGACSSFSEDDDSA

CNGA1

31

P29973
SSSSSSCEQDGVEND

C11orf16

336

Q9NQ32
VGDSCDTNQDSDGDG

THBS4

621

P35443
QEDSNSDGVGDICES

THBS4

691

P35443
SSLSGNSDGGEEFCE

SRFBP1

241

Q8NEF9
SNDFSNDDGVDEGIC

USP47

451

Q96K76
GDNDSENGLCTEDTC

USP15

686

Q9Y4E8
ASSGAGAESFEQCRD

TLNRD1

66

Q9H1K6
FDGSSNCNSREQSDD

SASH1

236

O94885
DGFLADDNCSSEIGQ

SENP6

946

Q9GZR1
SGGQLQDLDCSSSDD

SRPRA

286

P08240
AIQDFTCDDGNDDNS

SLIT2

706

O94813
VSQSDAFEGSDFSCA

REL

556

Q04864
DAEETANQTCGGTDS

RRN3P2

241

A6NIE6
AESLDGGCSSSSEDQ

TCF20

516

Q9UGU0
DQQNSDTDSFGDACD

THBS3

526

P49746
CDTNEDSDGDGHQDT

THBS3

621

P49746
ESSGSDDDCSSQASF

PLEKHH1

491

Q9ULM0
TDNGTTCNDFASSGD

SUCNR1

166

Q9BXA5
SICGSSGEEFFNNCE

ZNF770

441

Q6IQ21
FVDADFSDNVCSGNT

PLEKHG1

1306

Q9ULL1
QTCTDNTGDSDDSAS

TUT4

216

Q5TAX3
QESNGEGNCLSSSAS

ZNF106

971

Q9H2Y7
AATDSSCTSGAEQND

ZNF106

996

Q9H2Y7
GNGNNFESREACEES

WFIKKN2

421

Q8TEU8
PNESSEEAAGSSESC

GUCY1A1

26

Q02108
CDGSAECQDGSDESQ

LDLR

46

P01130