Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

8.84e-09101655GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

8.84e-09101655GO:0005391
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.61e-08111655GO:0008556
GeneOntologyMolecularFunctionATP-dependent activity

MYO1A TDRD9 ABCA13 KIF26B DDX60 CFTR DHX57 MLH3 DDX50 DNAH17 SHOC1 ATP6V0D2 ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 DNAH5 DNAH8

8.16e-0761416519GO:0140657
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA13 CFTR ATP6V0D2 ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

3.43e-061091658GO:0042626
GeneOntologyMolecularFunctionATP hydrolysis activity

TDRD9 ABCA13 DDX60 CFTR DHX57 MLH3 DDX50 SHOC1 ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 DNAH5 DNAH8

4.05e-0644116515GO:0016887
GeneOntologyMolecularFunctionsodium ion binding

SCN2A SCN9A ATP1A1 ATP1A2

4.22e-06141654GO:0031402
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.11e-05361655GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.11e-05361655GO:0015662
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP6V0D2 ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.22e-05621656GO:0019829
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.28e-051711659GO:0015081
GeneOntologyMolecularFunctionsteroid hormone binding

ATP1A1 ATP1A2 ATP1A3

1.89e-0571653GO:1990239
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MTG1 TDRD9 ABCA13 DDX60 CFTR DHX57 RGS7 TUBB1 MLH3 DDX50 SHOC1 ATP1A1 ATP1A2 ATP1A3 ATP12A DNM1 ATP1A4 DNAH5 DNAH8

2.31e-0577516519GO:0017111
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN2A SCN4A SCN5A SCN9A

5.83e-05261654GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

SCN2A SCN9A ATP1A1 ATP1A2

5.83e-05261654GO:0031420
GeneOntologyMolecularFunctionpyrophosphatase activity

MTG1 TDRD9 ABCA13 DDX60 CFTR DHX57 RGS7 TUBB1 MLH3 DDX50 SHOC1 ATP1A1 ATP1A2 ATP1A3 ATP12A DNM1 ATP1A4 DNAH5 DNAH8

6.72e-0583916519GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

MTG1 TDRD9 ABCA13 DDX60 CFTR DHX57 RGS7 TUBB1 MLH3 DDX50 SHOC1 ATP1A1 ATP1A2 ATP1A3 ATP12A DNM1 ATP1A4 DNAH5 DNAH8

6.83e-0584016519GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

MTG1 TDRD9 ABCA13 DDX60 CFTR DHX57 RGS7 TUBB1 MLH3 DDX50 SHOC1 ATP1A1 ATP1A2 ATP1A3 ATP12A DNM1 ATP1A4 DNAH5 DNAH8

6.83e-0584016519GO:0016818
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA13 CFTR ATP6V0D2 ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.19e-041781658GO:0015399
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH17 DYNLT5 DNAH5 DNAH8

2.40e-04371654GO:0045505
GeneOntologyMolecularFunctionprotein-folding chaperone binding

FNIP2 CFTR TSC1 PPEF2 ATP1A1 ATP1A2 ATP1A3

3.89e-041611657GO:0051087
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH5 DNAH8

4.13e-04181653GO:0008569
GeneOntologyMolecularFunctionsodium channel activity

SCN2A SCN4A SCN5A SCN9A

8.94e-04521654GO:0005272
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

RAG1 TDRD9 DDX60 RPP38 DHX57 HMCES POLR3C MLH3 DDX50 POLK EXOSC7 CNOT1 NIPBL DNMT1

9.56e-0464516514GO:0140640
GeneOntologyMolecularFunctioncytoskeletal anchor activity

SORBS2 NCK1 NCK2

9.87e-04241653GO:0008093
GeneOntologyMolecularFunctionATPase inhibitor activity

FNIP2 TSC1

9.96e-0461652GO:0042030
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor activity

FLT1 KDR

1.39e-0371652GO:0005021
GeneOntologyMolecularFunctioncentromeric DNA binding

MLH3 ZW10

1.39e-0371652GO:0019237
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH17 DNAH5 DNAH8

1.56e-03281653GO:0051959
GeneOntologyMolecularFunctionclathrin binding

LDLRAP1 SYT6 SYT10 CLTB

1.83e-03631654GO:0030276
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF26B DNAH17 DNAH5 DNAH8

2.70e-03701654GO:0003777
GeneOntologyMolecularFunctionphosphatase activity

CAMK2G PTPRU PPEF2 SSH1 PTPRQ SSH2 ATP1A1 ATP1A2

2.72e-032871658GO:0016791
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1A KIF26B DNAH17 DNAH5 DNAH8

3.00e-031181655GO:0003774
GeneOntologyBiologicalProcessestablishment or maintenance of transmembrane electrochemical gradient

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.37e-08111655GO:0010248
GeneOntologyBiologicalProcessintracellular potassium ion homeostasis

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.77e-07171655GO:0030007
GeneOntologyBiologicalProcesssodium ion export across plasma membrane

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.77e-07171655GO:0036376
GeneOntologyBiologicalProcesssodium ion transmembrane transport

CFTR SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 WNK2

9.55e-0720816511GO:0035725
GeneOntologyBiologicalProcesssodium ion transport

CFTR TGFB1 SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 WNK2

2.30e-0627516512GO:0006814
GeneOntologyBiologicalProcesspotassium ion import across plasma membrane

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 WNK2

3.20e-06511656GO:1990573
GeneOntologyBiologicalProcessintracellular sodium ion homeostasis

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

3.74e-06301655GO:0006883
GeneOntologyBiologicalProcessresponse to glycoside

ATP1A1 ATP1A2 ATP1A3

4.97e-0651653GO:1903416
GeneOntologyBiologicalProcessmembrane depolarization

CFTR SCN2A SCN4A SCN5A SCN9A KDR ATP1A2 ATP1A3

5.92e-061211658GO:0051899
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN2A SCN4A SCN5A SCN9A ATP1A2

9.51e-06361655GO:0086010
GeneOntologyBiologicalProcesspotassium ion homeostasis

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.09e-05371655GO:0055075
GeneOntologyBiologicalProcesssodium ion homeostasis

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

5.38e-05511655GO:0055078
GeneOntologyBiologicalProcesscardiac muscle contraction

PSEN2 SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3

6.10e-051671658GO:0060048
GeneOntologyBiologicalProcessblood circulation

IL18 PSEN2 CFTR ARHGEF12 PPARA TGFB1 DOCK5 MYLK3 SCN2A SCN4A SCN5A SCN9A KDR ATP1A1 ATP1A2 ATP1A3

6.68e-0564816516GO:0008015
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2

7.08e-05871656GO:0086001
GeneOntologyBiologicalProcessresponse to abiotic stimulus

RAG1 FLT1 IL18 PSEN2 MAP1B HUS1 CAMK2G FBXL17 TSC1 PPARA BBS10 TGFB1 PJVK SCN2A PTPRQ SCN9A KDR PLAU SPIDR ATP1A1 ATP1A2 ATP1A3 POLK NIPBL GPR151

8.28e-05136116525GO:0009628
GeneOntologyBiologicalProcesscirculatory system process

IL18 PSEN2 CFTR ARHGEF12 PPARA TGFB1 DOCK5 MYLK3 SCN2A SCN4A SCN5A SCN9A KDR ATP1A1 ATP1A2 ATP1A3 ATP1A4

8.46e-0573316517GO:0003013
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2

1.03e-04931656GO:0086003
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

IL18 MYO1A WFS1 AQP4 OTOGL PJVK PTPRQ SCN9A NIPBL

1.31e-042381659GO:0050954
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN2A SCN4A SCN5A SCN9A ATP1A1

1.38e-04621655GO:0086002
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SCN5A ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 WNK2

1.48e-041421657GO:0098659
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SCN5A ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 WNK2

1.48e-041421657GO:0099587
GeneOntologyBiologicalProcessDNA recombination

RAG1 RNF169 HUS1 NBN HMCES TGFB1 MLH3 ARID2 SHOC1 SPIDR NIPBL

1.91e-0436816511GO:0006310
GeneOntologyBiologicalProcessprotein dephosphorylation

TSC1 NCK1 PTPRU PPEF2 TGFB1 SSH1 PTPRQ SSH2 NCK2

2.26e-042561659GO:0006470
GeneOntologyBiologicalProcessactin filament-based movement

MYO1A SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2

2.35e-041531657GO:0030048
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN2A SCN4A SCN5A SCN9A ATP1A2 ATP1A3

2.84e-041121656GO:0019226
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DRC1 DNAH17 DNAH5 DNAH8

3.17e-04411654GO:0070286
GeneOntologyBiologicalProcesspotassium ion transport

TSC1 RGS7 SCN4A ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 WNK2

3.53e-042721659GO:0006813
GeneOntologyBiologicalProcessstriated muscle contraction

PSEN2 SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3

3.69e-042171658GO:0006941
GeneOntologyBiologicalProcessnegative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

NCK1 NCK2

3.78e-0441652GO:1903912
GeneOntologyCellularComponentsodium:potassium-exchanging ATPase complex

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.72e-06121644GO:0005890
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP6V0D2 ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

2.25e-06491646GO:0090533
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP6V0D2 ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

4.49e-06551646GO:0098533
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN2A SCN4A SCN5A SCN9A

8.03e-06171644GO:0001518
GeneOntologyCellularComponentaxonemal dynein complex

DRC1 DNAH17 DNAH5 DNAH8

4.06e-05251644GO:0005858
GeneOntologyCellularComponentdynein complex

DRC1 DNAH17 DYNLT5 DNAH5 DNAH8

6.48e-05541645GO:0030286
GeneOntologyCellularComponentsodium channel complex

SCN2A SCN4A SCN5A SCN9A

7.44e-05291644GO:0034706
GeneOntologyCellularComponentouter dynein arm

DNAH17 DNAH5 DNAH8

9.90e-05121643GO:0036157
GeneOntologyCellularComponentaxon

LDLRAP1 DIP2B MYO1A MAP1B MYCBP2 CYP19A1 LRRC4B TSC1 GRM3 TGFB1 SSH1 SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A3 DNM1

2.28e-0489116418GO:0030424
GeneOntologyCellularComponentpresynaptic membrane

PSEN2 LRRC4B GRM3 RGS7 SCN2A CLTB ATP1A3 DNM1 GPR151

3.50e-042771649GO:0042734
GeneOntologyCellularComponentphotoreceptor inner segment membrane

ATP1A1 ATP1A3

3.63e-0441642GO:0060342
GeneOntologyCellularComponentphotoreceptor inner segment

USP45 PPEF2 ATP1A1 ATP1A3 DNM1

3.72e-04781645GO:0001917
GeneOntologyCellularComponentT-tubule

AQP4 SCN2A SCN5A ATP1A1 ATP1A2

3.95e-04791645GO:0030315
GeneOntologyCellularComponentglutamatergic synapse

PSEN2 HTR4 MAP1B SYT6 LRRC4B LRRC4C GRM3 LRRC4 SYT10 RGS7 ELMO1 DIP2A IL1RAPL2 SCN2A RNF216 DNM1

7.18e-0481716416GO:0098978
GeneOntologyCellularComponentpostsynapse

HTR4 MAP1B CAMK2G CYP19A1 LRRC4B TSC1 LRRC4C GRM3 LRRC4 RGS7 ELMO1 DIP2A CLTB RNF216 ATP1A1 ATP1A2 ATP1A3 NCK2

1.09e-03101816418GO:0098794
GeneOntologyCellularComponentstereocilium base

PJVK PTPRQ

1.66e-0381642GO:0120044
GeneOntologyCellularComponentmicrotubule associated complex

MAP1B DRC1 DNAH17 DYNLT5 DNAH5 DNAH8

1.72e-031611646GO:0005875
GeneOntologyCellularComponentintercalated disc

SCN2A SCN5A ATP1A1 ATP1A2

2.01e-03681644GO:0014704
GeneOntologyCellularComponentsynaptic membrane

PSEN2 SYT6 LRRC4B LRRC4C GRM3 LRRC4 RGS7 SCN2A CLTB ATP1A3 DNM1 GPR151

2.22e-0358316412GO:0097060
DomainP-type_ATPase_IIC

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

2.50e-1061595IPR005775
DomainATPase_P-typ_TM_dom

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.70e-07161595IPR023298
Domain-

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.70e-071615951.20.1110.10
DomainATPase_P-typ_cation-transptr_C

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

2.39e-07171595IPR006068
DomainCation_ATPase_C

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

2.39e-07171595PF00689
DomainCation_ATPase_N

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

3.29e-07181595PF00690
DomainCation_ATPase_N

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

3.29e-07181595SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

4.43e-07191595IPR004014
DomainNa_channel_asu

SCN2A SCN4A SCN5A SCN9A

1.02e-06101594IPR001696
DomainNa_trans_assoc

SCN2A SCN4A SCN5A SCN9A

1.02e-06101594IPR010526
DomainNa_trans_assoc

SCN2A SCN4A SCN5A SCN9A

1.02e-06101594PF06512
DomainARM-like

IPO5 MROH2A WDFY4 ELMO1 SF3B1 AP1G1 ARID2 RRP12 CEP70 ASPM MROH7 NIPBL

3.54e-0627015912IPR011989
DomainIQ

MYO1A PPEF2 SCN2A SCN4A SCN5A SCN9A ASPM

5.82e-06811597SM00015
DomainDMAP_binding

DIP2B DIP2A DNMT1

5.98e-0651593PF06464
Domain-

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

7.02e-063215953.40.1110.10
Domain-

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

7.02e-063215952.70.150.10
DomainATPase_P-typ_cyto_domN

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.11e-05351595IPR023299
DomainIQ_motif_EF-hand-BS

MYO1A PPEF2 SCN2A SCN4A SCN5A SCN9A ASPM

1.17e-05901597IPR000048
DomainNa_trans_cytopl

SCN2A SCN5A SCN9A

1.19e-0561593PF11933
DomainDMAP1-bd

DIP2B DIP2A DNMT1

1.19e-0561593IPR010506
DomainNa_trans_cytopl

SCN2A SCN5A SCN9A

1.19e-0561593IPR024583
DomainDMAP_binding

DIP2B DIP2A DNMT1

1.19e-0561593SM01137
DomainATPase_P-typ_P_site

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.28e-05361595IPR018303
DomainP_typ_ATPase

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.28e-05361595IPR001757
DomainATPASE_E1_E2

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.28e-05361595PS00154
DomainIQ

MYO1A PPEF2 SCN2A SCN4A SCN5A SCN9A ASPM

1.46e-05931597PS50096
DomainATPase_P-typ_transduc_dom_A

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.47e-05371595IPR008250
DomainE1-E2_ATPase

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.47e-05371595PF00122
DomainARM-type_fold

IPO5 MROH2A WDFY4 ELMO1 DOCK5 SF3B1 AP1G1 ARID2 RRP12 ASPM MROH7 NIPBL

3.45e-0533915912IPR016024
DomainNCK

NCK1 NCK2

7.20e-0521592IPR017304
Domain-

IPO5 WDFY4 ELMO1 SF3B1 AP1G1 RRP12 ASPM MROH7 NIPBL

1.23e-0422215991.25.10.10
DomainHEAT_REPEAT

IPO5 MROH2A SF3B1 MROH7 NIPBL

3.25e-04701595PS50077
DomainIQ

MYO1A PPEF2 SCN4A SCN9A ASPM

3.48e-04711595PF00612
DomainDEAD/DEAH_box_helicase_dom

TDRD9 DDX60 DHX57 CMSS1 DDX50

3.96e-04731595IPR011545
DomainDEAD

TDRD9 DDX60 DHX57 CMSS1 DDX50

3.96e-04731595PF00270
DomainDEK_C

SSH1 SSH2

4.27e-0441592PF08766
DomainDEK_C

SSH1 SSH2

4.27e-0441592IPR014876
DomainPLAC

ADAMTS19 ADAMTSL1 ADAMTS12

5.31e-04191593PS50900
DomainPLAC

ADAMTS19 ADAMTSL1 ADAMTS12

5.31e-04191593IPR010909
DomainHAD-like_dom

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

5.70e-04791595IPR023214
DomainP-loop_NTPase

MTG1 MYO1A TDRD9 ABCA13 KIF26B DDX60 CFTR DHX57 CMSS1 SAMD9L CTPS2 DDX50 ASPM DNM1 DNAH5 DNAH8 NLRP5

9.21e-0484815917IPR027417
DomainPeptidase_M12B_ADAM-TS

ADAMTS19 ADAMTSL1 ADAMTS12

1.07e-03241593IPR013273
DomainIg_I-set

FLT1 ADAMTSL1 AXL LRRC4B LRRC4C LRRC4 KDR

1.23e-031901597IPR013098
DomainI-set

FLT1 ADAMTSL1 AXL LRRC4B LRRC4C LRRC4 KDR

1.23e-031901597PF07679
DomainChannel_four-helix_dom

SCN2A SCN4A SCN5A SCN9A

1.41e-03571594IPR027359
Domain-

SCN2A SCN4A SCN5A SCN9A

1.41e-035715941.20.120.350
DomainTyr_kinase_rcpt_3_CS

FLT1 KDR

1.95e-0381592IPR001824
DomainDHC_N1

DNAH5 DNAH8

1.95e-0381592PF08385
DomainRECEPTOR_TYR_KIN_III

FLT1 KDR

1.95e-0381592PS00240
DomainDynein_heavy_dom-1

DNAH5 DNAH8

1.95e-0381592IPR013594
PathwayKEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION

GLS2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.50e-06231255M4361
PathwayREACTOME_CARDIAC_CONDUCTION

CAMK2G SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3 ATP1A4

2.27e-061301259M27454
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

CAMK2G SCN2A SCN4A SCN5A SCN9A

8.41e-06321255M27455
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

CAMK2G ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

8.75e-06551256M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

CAMK2G ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.08e-05571256MM15643
PathwayREACTOME_MUSCLE_CONTRACTION

CAMK2G SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3 ATP1A4

8.07e-052031259M5485
PathwayREACTOME_L1CAM_INTERACTIONS

RPS6KA5 TUBB1 SCN2A SCN4A SCN5A SCN9A DNM1

9.96e-051211257M872
PathwayREACTOME_ION_HOMEOSTASIS

CAMK2G ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.13e-04541255M27460
PathwayREACTOME_ION_HOMEOSTASIS

CAMK2G ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.13e-04541255MM15202
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN2A SCN4A SCN5A SCN9A

1.54e-04311254M877
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CAMK2G ATP6V0D2 ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 WNK2

2.24e-041831258M997
PathwayREACTOME_SIGNALING_BY_VEGF

FLT1 AXL NCK1 ELMO1 KDR NCK2

3.05e-041031256MM14752
PathwayREACTOME_SIGNALING_BY_VEGF

FLT1 AXL NCK1 ELMO1 KDR NCK2

3.57e-041061256M27077
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SORBS2 GLS2 HTR4 TCN1 TSC1 GRM3 SCN2A SCN4A SCN5A SCN9A DNMT1

4.20e-0436712511M48346
Pubmed

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

2.55e-12516953035563
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.53e-11616953036582
Pubmed

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.

ATP1A1 ATP1A2 ATP1A3 ATP1A4

5.38e-104169421849490
Pubmed

Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.86e-087169410837135
Pubmed

Molecular genetics of Na,K-ATPase.

ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.86e-08716942158121
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN2A SCN4A SCN5A SCN9A

6.65e-089169416382098
Pubmed

Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.

ATP1A1 ATP1A2 ATP1A3

1.13e-073169330819023
Pubmed

Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.

ATP1A1 ATP1A2 ATP1A3

1.13e-073169319058785
Pubmed

Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.

ATP1A1 ATP1A2 ATP1A3

1.13e-07316938203495
Pubmed

Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.

ATP1A1 ATP1A2 ATP1A3

1.13e-073169325994790
Pubmed

Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.

ATP1A1 ATP1A2 ATP1A3

1.13e-07316932822726
Pubmed

Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.

ATP1A1 ATP1A3 ATP1A4

1.13e-073169326373354
Pubmed

Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.

ATP1A1 ATP1A2 ATP1A3

1.13e-073169317947306
Pubmed

Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.

ATP1A1 ATP1A2 ATP1A3

1.13e-073169328465228
Pubmed

Na,K-ATPase and the role of alpha isoforms in behavior.

ATP1A1 ATP1A2 ATP1A3

1.13e-073169318044013
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN5A SCN9A

1.13e-073169320038812
Pubmed

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.

ATP1A1 ATP1A2 ATP1A3

1.13e-073169326911348
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

IPO5 SORBS2 MAP1B WFS1 CAMK2G ARHGEF12 DHX57 TSC1 GRM3 ELP3 AQP4 GRAMD1B DIP2A SF3B1 AP1G1 SCN2A SSH2 ATP1A1 ATP1A2 ATP1A3 DNM1 CNOT1 WNK2 NCK2

1.28e-0714311692437142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

GGNBP2 GLS2 MYO1A MAP1B CAMK2G DHX57 TSC1 PPARA PGK2 ADAMTS12 SF3B1 DDX50 KIAA0825 SCN4A SCN9A ASPM KDR ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4 DNAH8 NIPBL

1.47e-0714421692435575683
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

2.76e-0729169515071553
Pubmed

Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes.

TGFB1 ATP1A1 ATP1A2 ATP1A3 ATP12A

3.30e-073016952842249
Pubmed

Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.

FLT1 KDR PLAU

4.49e-074169327151212
Pubmed

Immunolocalizations of VEGF, its receptors flt-1, KDR and TGF-beta's in epithelial ovarian tumors.

FLT1 TGFB1 KDR

4.49e-074169316835828
Pubmed

Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.

ATP1A1 ATP1A2 ATP1A3

4.49e-074169319751721
Pubmed

Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.

ATP1A1 ATP1A2 ATP1A3

4.49e-074169319376779
Pubmed

Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.

ATP1A1 ATP1A2 ATP1A3

4.49e-074169317234593
Pubmed

Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.

ATP1A1 ATP1A3 ATP1A4

4.49e-07416932887455
Pubmed

Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.

ATP1A1 ATP1A2 ATP1A3

4.49e-074169321731499
Pubmed

The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.

ATP1A1 ATP1A2 ATP1A3

4.49e-074169312458206
Pubmed

Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.

ATP1A1 ATP1A2 ATP1A3

4.49e-074169317446412
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

IPO5 DDX60 DHX57 DOCK5 RRP12 MROH7 ATP1A1 CNOT1 DNMT1

7.05e-07202169933005030
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN4A SCN5A

1.12e-065169317724025
Pubmed

Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.

ATP1A1 ATP1A2 ATP12A

1.12e-065169316870707
Pubmed

PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.

PPARA ATP1A1 ATP1A2 ATP1A3

1.22e-0617169436230906
Pubmed

Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.

ATP1A1 ATP1A2 ATP1A3

2.23e-066169310636900
Pubmed

Expression and distribution of Na, K-ATPase isoforms in the human uterus.

ATP1A1 ATP1A2 ATP1A3

3.89e-067169320065300
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH5 DNAH8

3.89e-067169331178125
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

IPO5 MAP1B CNOT10 RPP38 LENG8 ZNF106 DDX50 AP1G1 ZW10 EXOSC7 NIPBL

5.84e-064101691126949251
Pubmed

Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.

NCK1 KDR NCK2

6.20e-068169326659946
Pubmed

Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.

ATP1A1 ATP1A2 ATP1A3

6.20e-068169319683723
Pubmed

Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.

ATP1A1 ATP1A2 ATP1A3

6.20e-06816932885848
Pubmed

Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.

ATP1A1 ATP1A2 ATP1A3

6.20e-068169323652595
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

GGNBP2 MROH2A DHX57 CMSS1 PCGF5 TGFB1 DOCK5 DDX50 FAM222A RRP12 MROH7 EXOSC7

6.24e-064961691231343991
Pubmed

The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.

ATP1A1 ATP1A2 ATP1A3

9.27e-069169315253893
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN2A SCN4A SCN5A

9.27e-069169315746173
Pubmed

The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals.

NCK1 DNM1 NCK2

9.27e-069169311557983
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

RPS6KA5 CAMK2G PTPRU PCGF5 ADAMTS12 SSH1 DNAH17 SSH2 ATP1A1 ATP1A2 ATP1A3 DNM1 DNAH5 WNK2

1.46e-057301691434857952
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

FLT1 AXL LRRC4B LRRC4C PTPRU LRRC4 KDR

1.53e-05162169725826454
Pubmed

Flt1/VEGFR1 heterozygosity causes transient embryonic edema.

FLT1 LYVE1 KDR

1.81e-0511169327251772
Pubmed

Deciphering epiblast lumenogenesis reveals proamniotic cavity control of embryo growth and patterning.

CFTR AQP4 ATP1A1

1.81e-0511169333692105
Pubmed

Expression of vascular endothelial growth factor receptors in the endometrium of septate uterus.

FLT1 KDR

2.35e-052169219200976
Pubmed

Production of VEGF receptor 1 and 2 mRNA and protein during endochondral bone repair is differential and healing phase specific.

FLT1 KDR

2.35e-052169220947709
Pubmed

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.

SCN4A SCN9A

2.35e-052169218079277
Pubmed

TGF-beta 1 downregulates CFTR expression and function in nasal polyps of non-CF patients.

CFTR TGFB1

2.35e-052169215361357
Pubmed

VEGFR1 and VEGFR2 in lip carcinogenesis and its association with microvessel density.

FLT1 KDR

2.35e-052169225895461
Pubmed

VEGFR1 and VEGFR2 in Alzheimer's Disease.

FLT1 KDR

2.35e-052169229226875
Pubmed

Expression of VEGF receptors on endothelial cells in mouse skeletal muscle.

FLT1 KDR

2.35e-052169222984559
Pubmed

Molecular cloning of the mouse ouabain-resistance gene.

ATP1A1 ATP1A2

2.35e-05216926324196
Pubmed

Effect of TGFβ on Na+/K+ ATPase activity in megakaryocytes.

TGFB1 ATP1A1

2.35e-052169225168590
Pubmed

Quantitative assessment and clinical relevance of VEGFRs-positive tumor cells in refractory brain tumors.

FLT1 KDR

2.35e-052169232088190
Pubmed

Expression of vascular endothelial growth factor receptors during male germ cell differentiation in the mouse.

FLT1 KDR

2.35e-052169212773425
Pubmed

[Changes of plasma uPA and TGF-beta1 in patients with preeclampsia].

TGFB1 PLAU

2.35e-052169220369484
Pubmed

Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.

FLT1 KDR

2.35e-052169215611243
Pubmed

TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis.

RAG1 TGFB1

2.35e-052169218669656
Pubmed

Inhibition of prostate cancer osteoblastic progression with VEGF121/rGel, a single agent targeting osteoblasts, osteoclasts, and tumor neovasculature.

FLT1 KDR

2.35e-052169221343372
Pubmed

Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.

NCK1 NCK2

2.35e-052169219596797
Pubmed

Involvement of VEGFR-2 (kdr/flk-1) but not VEGFR-1 (flt-1) in VEGF-A and VEGF-C-induced tube formation by human microvascular endothelial cells in fibrin matrices in vitro.

FLT1 KDR

2.35e-052169211824379
Pubmed

NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors.

LRRC4B LRRC4C

2.35e-052169231166939
Pubmed

Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades.

FLT1 KDR

2.35e-052169220103598
Pubmed

Role of TGF Beta and PPAR Alpha Signaling Pathways in Radiation Response of Locally Exposed Heart: Integrated Global Transcriptomics and Proteomics Analysis.

PPARA TGFB1

2.35e-052169227805817
Pubmed

Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

ATP1A1 ATP1A3

2.35e-052169224391932
Pubmed

Endothelial progenitor cells induce transplant arteriosclerosis via VEGFR-1/2 activity.

FLT1 KDR

2.35e-052169225437886
Pubmed

Interleukin 8 secretion from monocytes of subjects heterozygous for the deltaF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered.

IL18 CFTR

2.35e-052169215358638
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

2.35e-052169211834499
Pubmed

PPARα Is Necessary for Radiation-Induced Activation of Noncanonical TGFβ Signaling in the Heart.

PPARA TGFB1

2.35e-052169229560722
Pubmed

Endothelial cell-by-cell profiling reveals the temporal dynamics of VEGFR1 and VEGFR2 membrane localization after murine hindlimb ischemia.

FLT1 KDR

2.35e-052169223376830
Pubmed

Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.

ATP1A1 ATP1A3

2.35e-052169223761886
Pubmed

Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire.

NCK1 NCK2

2.35e-052169220709959
Pubmed

Hypoxia differentially regulates VEGFR1 and VEGFR2 levels and alters intracellular signaling and cell migration in endothelial cells.

FLT1 KDR

2.35e-052169221168388
Pubmed

Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction.

FLT1 KDR

2.35e-052169229158084
Pubmed

Mice expressing ouabain-sensitive α1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy.

ATP1A1 ATP1A2

2.35e-052169220952666
Pubmed

The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.

ATP1A1 ATP1A3

2.35e-05216923030810
Pubmed

Randomized Phase II Study of Ramucirumab or Icrucumab in Combination with Capecitabine in Patients with Previously Treated Locally Advanced or Metastatic Breast Cancer.

FLT1 KDR

2.35e-052169228220020
Pubmed

Comparative study of human colonic tumor-derived endothelial cells (HCTEC) and normal colonic microvascular endothelial cells (HCMEC): Hypoxia-induced sVEGFR-1 and sVEGFR-2 levels.

FLT1 KDR

2.35e-052169219287991
Pubmed

Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development.

NCK1 NCK2

2.35e-052169237479911
Pubmed

Immunohistochemical expression of vascular endothelial growth factor A (VEGF), and its receptors (VEGFR1, 2) in normal and pathologic conditions of the human thymus.

FLT1 KDR

2.35e-052169218356031
Pubmed

Comparative structure-function analysis of VEGFR-1 and VEGFR-2: What have we learned from chimeric systems?

FLT1 KDR

2.35e-052169212814952
Pubmed

Characteristic genetic spectrum of primary ciliary dyskinesia in Japanese patients and global ethnic heterogeneity: population-based genomic variation database analysis.

DRC1 DNAH5

2.35e-052169236864285
Pubmed

Aquaporin-4 deficiency reduces TGF-β1 in mouse midbrains and exacerbates pathology in experimental Parkinson's disease.

AQP4 TGFB1

2.35e-052169230680924
Pubmed

Absence of mutations in the activation loop and juxtamembrane domains of VEGFR-1 and VEGFR-2 gene in chronic myelomonocytic leukemia (CMML).

FLT1 KDR

2.35e-052169222153185
Pubmed

Apoptosis of pulmonary microvascular endothelial cells stimulates vascular smooth muscle cell growth.

TGFB1 KDR

2.35e-052169216617095
Pubmed

Angiogenesis in systemic sclerosis: impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions.

FLT1 KDR

2.35e-052169218975312
Pubmed

Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.

ATP1A1 ATP1A3

2.35e-052169221498719
Pubmed

Non-compensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration.

NCK1 NCK2

2.35e-052169219242519
Pubmed

Expression of vascular endothelial growth factor receptors is closely related to the histological grade of hepatocellular carcinoma.

FLT1 KDR

2.35e-052169216786116
Pubmed

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.

ATP1A1 ATP1A2

2.35e-052169219376809
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

2.35e-052169226861708
Pubmed

A cyclic peptide reproducing the α1 helix of VEGF-B binds to VEGFR-1 and VEGFR-2 and inhibits angiogenesis and tumor growth.

FLT1 KDR

2.35e-052169230700502
Pubmed

A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase.

ATP1A1 ATP1A2

2.35e-052169235446892
Pubmed

New molecular determinants controlling the accessibility of ouabain to its binding site in human Na,K-ATPase alpha isoforms.

ATP1A1 ATP1A2

2.35e-052169214742675
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A1 ATP1A2 ATP1A3 ATP1A4

5.17e-08711441208
GeneFamilySodium voltage-gated channel alpha subunits

SCN2A SCN4A SCN5A SCN9A

1.84e-07911441203
GeneFamilySlingshot protein phosphatases

SSH1 SSH2

1.18e-0431142898
GeneFamilyDyneins, axonemal

DNAH17 DNAH5 DNAH8

1.56e-04171143536
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FLT1 ADAMTSL1 LRRC4B LRRC4C LRRC4 KDR

5.49e-041611146593
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT1 AXL KDR

2.04e-03401143321
GeneFamilyMaestro heat like repeat containing

MROH2A MROH7

2.09e-03111142636
GeneFamilyCCR4-NOT transcription complex

CNOT10 CNOT1

2.09e-031111421023
CoexpressionGSE36078_UNTREATED_VS_AD5_INF_IL1R_KO_MOUSE_LUNG_DC_UP

CYP4V2 MAP1B MYCBP2 VPS13C FBXL17 NBN DECR1 ZNF106 DYNLT5

5.80e-062001679M9301
CoexpressionGSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_UP

AXL SYT6 TSC1 GRM3 DOCK5 SAMD9L DNAH17 ATP12A DNAH8

5.80e-062001679M7478
CoexpressionGSE11386_NAIVE_VS_MEMORY_BCELL_DN

USP45 MYCBP2 FBXL17 NBN TRIM39 DECR1 GRAMD1B NIPBL

8.21e-061581678M372
CoexpressionGSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN

RNF169 PSEN2 RPS6KA5 ZBTB8A DOCK5 DIP2A CLTB OSBPL1A

2.12e-051801678M8906
CoexpressionGSE32986_UNSTIM_VS_GMCSF_STIM_DC_UP

LDLRAP1 TCEA3 DIP2B DDX60 LINS1 RNF216 ATP1A1 NCK2

4.33e-051991678M8609
CoexpressionGSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_UP

MYCBP2 DRC1 HMCES SAMD9L MEIOC KDR ATP1A2 DNMT1

4.33e-051991678M6412
CoexpressionHALLMARK_MITOTIC_SPINDLE

SORBS2 ARHGEF12 TSC1 NCK1 PCGF5 CEP72 SSH2 NCK2

4.33e-051991678M5893
CoexpressionGSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_DN

DIP2B GGNBP2 TDRD9 MYCBP2 KIF26B FBXL17 MCCC1

5.37e-051511677M369
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 KIF26B MROH2A CFTR LRRC4C OTOGL SCN2A PTPRQ SCN9A ATP1A4 DNAH5

1.31e-10184169112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 KIF26B MROH2A CFTR LRRC4C OTOGL SCN2A PTPRQ SCN9A ATP1A4 DNAH5

1.31e-1018416911ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 KIF26B MROH2A CFTR LRRC4C OTOGL SCN2A PTPRQ SCN9A ATP1A4 DNAH5

1.31e-10184169112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 HTR4 CFTR SYT10 ST8SIA6 SHOC1 ATP6V0D2 EXOSC7

1.52e-0917616910c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 CFTR SYT10 ST8SIA6 SHOC1 ATP6V0D2 EXOSC7

9.44e-091571699c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 SYT10 ST8SIA6 HTD2 SCN2A SHOC1 ATP6V0D2 EXOSC7

1.11e-08160169986fde32f096eaf9ea3677f57169cdcc0a57bb8dd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 CFTR SYT10 ST8SIA6 SCN2A SHOC1 ATP6V0D2 EXOSC7

1.46e-0816516999bd332e5ede759a00a47728ea5558c215efdd77a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 CFTR SYT10 ST8SIA6 SHOC1 ATP6V0D2 EXOSC7

2.31e-0817416995f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 CFTR SYT10 ST8SIA6 SHOC1 ATP6V0D2 EXOSC7

2.43e-08175169977c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 CFTR SYT10 ST8SIA6 SHOC1 ATP6V0D2 EXOSC7

2.55e-08176169925ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 CFTR SYT10 ST8SIA6 MEIOC SHOC1 ATP6V0D2 EXOSC7

4.30e-0818716997b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

SYT6 LRRC4C SYT10 ELMO1 SCN2A SCN9A ATP1A1 ATP1A3 DNM1

4.93e-0819016996e92c78799f34b31d098854503c796edb0dc7f80
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ADAMTSL1 GALNT18 ELMO1 LYVE1 SSH1 ST6GALNAC3 DYNLT5 KDR

6.16e-081951699818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 HTR4 ELP3 SYT10 SHOC1 ATP6V0D2 EXOSC7

2.80e-0716916984b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 HTR4 ELP3 SYT10 SHOC1 ATP6V0D2 EXOSC7

2.80e-071691698a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 CFTR SYT10 ST8SIA6 SHOC1 ATP6V0D2 EXOSC7

3.66e-07175169898947a226b5a2ac7091ff9d34243ea7736add973
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTSL1 IL18 DPY19L2 CFTR SYT10 SCN2A ATP6V0D2 EXOSC7

3.82e-07176169845028197364c64e93e3ffe86aff773d47a477d49
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 CFTR SYT10 MEIOC SHOC1 ATP6V0D2 EXOSC7

3.99e-0717716988e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTSL1 IL18 DPY19L2 CFTR SYT10 SHOC1 ATP6V0D2 EXOSC7

5.13e-0718316985c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 MAP1B PTGDS DOCK5 MYLK3 ST6GALNAC3 PTPRQ VSIG8

7.38e-071921698ef0aba777072429a6ab7dcfcc305673975946580
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 MAP1B PTGDS DOCK5 MYLK3 ST6GALNAC3 PTPRQ VSIG8

7.67e-0719316983eaa0461618582a1754400624350d269d24e750a
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLT1 KIF26B ARHGEF12 GALNT18 ST8SIA6 ST6GALNAC3 DYNLT5 KDR

7.67e-071931698ad2df9b77999780860141be6ec366afc0172a331
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DPY19L2 CFTR AQP4 RGS7 FAM222A SCN9A MROH7 ATP6V0D2

8.62e-07196169850aaca81b593ff71790bb75403b2e4c3ab03a6d2
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DPY19L2 CFTR PPEF2 RGS7 ST8SIA6 IL1RAPL2 SCN9A WNK2

8.95e-0719716988f009a15f154b3bb184b489da4722b7c27de7e11
ToppCellCOVID-19-COVID-19_Severe-Others-HSPC|COVID-19_Severe / Disease, condition lineage and cell class

IL18 DPY19L2 ZBTB8A ST8SIA6 OSBPL1A SCN9A CEP70 DYNLT5

9.66e-07199169825de67b6c9c8d6bb9a538e071a40ef865906c95d
ToppCellCOVID-19-COVID-19_Mild-Others-HSPC|COVID-19_Mild / Disease, condition lineage and cell class

IL18 DPY19L2 TCN1 ERMP1 ST8SIA6 SCN9A CEP70 DYNLT5

9.66e-0719916980230103c37ae3aff58240739b89f2c36b1e39a69
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYP4V2 WFS1 CAMK2G GRM3 PTGDS AQP4 MROH7 ATP1A2

1.00e-0620016987a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR4 ABCA13 OTOGL PTPRQ SCN9A ATP12A WNK2

1.39e-06145169796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 OTOGL PTPRQ SCN9A ATP6V0D2 ATP12A WNK2

2.91e-061621697bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 HTR4 ELP3 SCN2A ATP6V0D2 EXOSC7

3.16e-061641697d847d509bb1791638032ade6755d8164586b5bd5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 HTR4 ELP3 SCN2A ATP6V0D2 EXOSC7

3.42e-0616616976fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 CFTR SCN2A SHOC1 ATP6V0D2

3.56e-061671697edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 MAP1B PTGDS MYLK3 ST6GALNAC3 PTPRQ VSIG8

4.00e-06170169760bbd738c12e64e483485586c30057304884f5a6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 HTR4 SYT10 SHOC1 ATP6V0D2 EXOSC7

4.49e-0617316970bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 LRRC4 SYT10 FAM222A SCN9A ATP1A2 ATP1A4

4.67e-061741697667035a11b68745fa8446d6c68214713be42710f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS19 ADAMTSL1 SYT6 PTPRU DIP2A CLEC2L NCK2

4.67e-06174169799eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 ELP3 SYT10 ST8SIA6 ATP6V0D2 EXOSC7

5.03e-061761697cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 CFTR SYT10 SHOC1 ATP6V0D2 EXOSC7

5.62e-061791697e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 PSEN2 CFTR RGS7 ATP6V0D2

5.83e-061801697cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 CFTR SYT10 SHOC1 ATP6V0D2

6.04e-06181169730729f0364f719c044712a51453e22dc2c1a232b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 CFTR SYT10 SHOC1 ATP6V0D2 EXOSC7

6.73e-061841697282118f8221fa383ffb81dfb5798a0b7f065f911
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac|normal_Pleural_Fluid / Location, Cell class and cell subclass

FNIP2 CYP4V2 FLT1 PSEN2 AXL ST6GALNAC3 DYNLT5

7.22e-0618616973314def702fe6a5056d0dadbb3a587c5d1a16412
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 MAP1B PTGDS MYLK3 ST6GALNAC3 PTPRQ VSIG8

7.22e-0618616971094c7140131454b2583200e1c01e81ccab3db23
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 CFTR SYT10 ST8SIA6 SHOC1 ATP6V0D2

7.22e-061861697a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 SORBS2 LBP PTPRU LYVE1 ST6GALNAC3 KDR

7.48e-0618716973827fa80e558b642f3e0036f5ee1a8b69f437e30
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 SORBS2 LBP PTPRU LYVE1 ST6GALNAC3 KDR

7.48e-0618716971bf696eb03422ea507d3efe58dda1d442a65225d
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 SORBS2 LBP PTPRU LYVE1 ST6GALNAC3 KDR

7.48e-061871697ebe4d1216cc0d4c079b413d5a5460cfd3a4af922
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 MAP1B PTGDS DOCK5 ST6GALNAC3 PTPRQ VSIG8

7.48e-06187169724c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

SORBS2 DPY19L2 GRAMD1B MYLK3 SCN5A ATP1A2 WNK2

7.48e-06187169778cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellControl-B_naive-9|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CTU2 DENND4C GRAMD1B FAM222A ZW10 DNMT1

7.59e-06123169636d509eae874733f1a4f8189ad3000136ff6425e
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAP1B KIF26B GALNT18 DOCK5 LYVE1 ST6GALNAC3 KDR

7.75e-061881697c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 MAP1B PTGDS MYLK3 ST6GALNAC3 PTPRQ VSIG8

7.75e-0618816979db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MAP1B MYCBP2 KIF26B PTPRU IL1RAPL2 SCN2A SCN9A

7.75e-061881697b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 MAP1B PTGDS MYLK3 ST6GALNAC3 PTPRQ VSIG8

7.75e-061881697047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellCOVID-19_Severe-HSPC|COVID-19_Severe / disease group, cell group and cell class

IL18 DPY19L2 ZBTB8A ST8SIA6 OSBPL1A CEP70 DYNLT5

8.02e-06189169796015439971e2e5b8d6294ca5a6b873c7774e925
ToppCellControl-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

FNIP2 SORBS2 LRRC4C PTGDS ST8SIA6 SSH1 EXOSC7

8.30e-0619016974e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 DPY19L2 RGS7 SCN2A SHOC1 ATP6V0D2

8.30e-061901697223587b5df037794a2cee234babf87d12bf48ac8
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

FLT1 MAP1B GALNT18 ADAMTS12 ST8SIA6 ST6GALNAC3 KDR

8.30e-061901697a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 MAP1B LRRC4C SYT10 OTOGL SCN9A ATP1A2

8.89e-061921697ac507fd7cf3b3e521a15ef03bb4e81eb23807985
ToppCellMS-Treg-exh_CD4|MS / Condition, Cell_class and T cell subcluster

DIP2B HUS1 ARHGEF12 TSC1 NCK1 ELP3 VSIG8

8.89e-061921697c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCell3'-Child09-12-SmallIntestine-Neuronal|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 MAP1B LRRC4C SYT10 OTOGL SCN9A ATP1A2

8.89e-06192169724f40dadec04f4f99c31000fa9f09d07148fa190
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 MAP1B LRRC4C SYT10 OTOGL SCN9A ATP1A2

8.89e-06192169771e04e197825856c6d4278fc76c58ab17ffa2387
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RAG1 MYO1A CFTR TUBB1 SCN5A

9.21e-067416950d705c42e7741b861ba5a9f1af83b2c5c6f23fb6
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RAG1 MYO1A CFTR TUBB1 SCN5A

9.21e-06741695c49bda52aa4ead9483c2f27d63458034e75699bd
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 LRRC4C SYT10 DOCK5 OTOGL SCN9A ATP1A2

9.51e-061941697d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 LRRC4C SYT10 DOCK5 OTOGL SCN9A ATP1A2

9.51e-061941697bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 LRRC4C SYT10 DOCK5 OTOGL SCN9A ATP1A2

9.51e-061941697408dfc7060095972a54ae37ae8105521df6fbbee
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 SORBS2 PTGDS TGFB1 LYVE1 DYNLT5 KDR

9.83e-0619516979ad4981c4d157edc752de206ab0d754aa14beab8
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

FLT1 GALNT18 ELMO1 ST8SIA6 ST6GALNAC3 DYNLT5 KDR

9.83e-06195169750a193475db1bb1e05b8590225a553688c372c14
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 CFTR SYT10 SHOC1 ATP6V0D2 EXOSC7

9.83e-061951697f7d9adadd37209ce1a38e5d621607b9c9270fed8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 GALNT18 ELMO1 LYVE1 SSH1 ST6GALNAC3 KDR

1.02e-0519616977cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DPY19L2 KIF26B CFTR RGS7 ST8SIA6 SCN9A ATP6V0D2

1.02e-051961697ef650ff106a76c1e926e13c7f002fbc452cc48ae
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SORBS2 ABCA13 ARHGEF12 CCDC80 GALNT18 ASPM DNAH5

1.02e-051961697af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

SORBS2 ABCA13 ARHGEF12 CCDC80 GALNT18 ASPM DNAH5

1.02e-0519616976d02d494196e3f857d53eea46d9419690d43beca
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FLT1 PTGDS HES2 LYVE1 ST8SIA6 DYNLT5 KDR

1.02e-05196169785b697db1c925eff8bbef9d74565c82be5a0ddcc
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1B LRRC4C SYT10 IL1RAPL2 OTOGL SCN9A ATP1A2

1.05e-0519716975c88a97e8e23a5cd61885acbe1ef339ae6a1e35a
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL1 HTR4 MAP1B SYT6 RGS7 SCN2A SCN5A

1.05e-0519716975593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCell3'-Adult-LargeIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 TDRD9 MAP1B AXL LRRC4C PTGDS SYT10

1.09e-0519816972488ea95003f218afb25ecc873805b825e6cc409
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO1A WDFY4 LYVE1 LPAR6 SCN9A PLAU DNM1

1.09e-051981697c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DPY19L2 CFTR PPEF2 SYT10 RGS7 IL1RAPL2 SCN9A

1.09e-0519816972591e08e3fbee86ac40f11becd8147d6d39fded6
ToppCell3'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 TDRD9 MAP1B AXL LRRC4C PTGDS SYT10

1.09e-051981697991db02a76f7506848827601e927cf997cb520d3
ToppCell3'-Adult-LargeIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 TDRD9 MAP1B AXL LRRC4C PTGDS SYT10

1.09e-05198169798ab27335d126fa7817a46953948e524d91248f8
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1B WFS1 CCDC80 LYVE1 ST6GALNAC3 SCN9A KDR

1.12e-0519916971587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1B WFS1 CCDC80 LYVE1 ST6GALNAC3 SCN9A KDR

1.12e-051991697a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS19 AXL CCDC80 LRRC4B PTGDS ADAMTS12 DNM1

1.16e-052001697747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1B WFS1 DOCK5 LYVE1 ST6GALNAC3 SCN9A KDR

1.16e-05200169776e90231aa94afc12e618da8ae314c51644acab4
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1B WFS1 DOCK5 LYVE1 ST6GALNAC3 SCN9A KDR

1.16e-052001697e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

SORBS2 MAP1B MYCBP2 RGS7 SCN2A ATP1A3 DNM1

1.16e-05200169748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

WWC3 DDX60 ARHGEF12 GALNT18 SAMD9L SCN9A KDR

1.16e-05200169789821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WFS1 CAMK2G GRM3 PTGDS AQP4 MROH7 ATP1A2

1.16e-052001697d0812817ef99608994193787a62d39adeb2070ca
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYCBP2 VPS13C DDX60 SAMD9L SF3B1 ZNF644 NIPBL

1.16e-05200169712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS19 AXL CCDC80 LRRC4B PTGDS ADAMTS12 DNM1

1.16e-052001697de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WFS1 CAMK2G GRM3 PTGDS AQP4 MROH7 ATP1A2

1.16e-052001697cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPY19L2 SYT10 MEIOC SCN2A SHOC1 ATP6V0D2

1.41e-05137169681cdb216e6c81acf9c2072f9d39e1a42612e1258
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

FLT1 LRRC4C GRM3 RGS7 ST8SIA6 TMEM132D

1.53e-05139169664c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A RFX4 OTOGL ST6GALNAC3 PTPRQ ATP12A

1.72e-051421696759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellSevere-B_intermediate-14|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DIP2B DDX60 ZBTB8A PTGDS DOCK5 MYLK3

1.72e-0514216969c7d5783302974b883bd887f997d094eb5925ec2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 HTR4 SYT10 ATP6V0D2 EXOSC7

1.87e-051441696cc11cce43d1af8ac63140d05faf215ae9a10cde1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 DPY19L2 CFTR SCN2A SHOC1 ATP6V0D2

1.94e-0514516969964d6d3769be2f35d86268fe044cecd1d5a1616
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 IL18 CFTR GRAMD1B SCN9A ATP6V0D2

2.02e-051461696ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
Drugouabagenin

ATP1A1 ATP1A2 ATP1A3 ATP12A

8.44e-07111654CID000010497
Drug22,23-dihydrobufalin

ATP1A1 ATP1A2 ATP1A3

3.70e-0651653CID000195392
Drugthevetin A

ATP1A1 ATP1A2 ATP1A3

3.70e-0651653CID000441873
Drug3-acetylstrophanthin

ATP1A1 ATP1A2 ATP1A3

3.70e-0651653CID003082282
DrugZonisamide

SCN2A SCN4A SCN5A SCN9A

5.88e-06171654DB00909
DrugAC1NE3N8

SORBS2 GLS2 HTR4 CFTR GUCY2C SCN4A SCN9A ATP1A2 ATP1A3

6.27e-061781659CID004636050
DrugETH157

ATP1A1 ATP1A2 ATP1A3

7.36e-0661653CID000563154
DrugScorpion Venoms

CFTR SCN2A SCN4A SCN9A

7.52e-06181654ctd:D012604
Drugdihydrodigitoxigenin

ATP1A1 ATP1A2 ATP1A3

1.28e-0571653CID000107549
Drugdeferoxamine mesylate salt; Down 200; 100uM; PC3; HG-U133A

MTG1 HTR4 HUS1 VPS13C CAMK2G NBN PTGDS ASPM PLAU

1.42e-051971659460_DN
Drugsenecioate

CFTR NBN MCCC1

2.04e-0581653CID000010931
Drugepsilon-rhodomycinone

DECR1 DNM1 DNMT1

3.04e-0591653CID000099207
Drugaldosterone

EVC2 IL18 HTR4 CYP19A1 CFTR PPARA SCN4A SCN9A PLAU ATP1A1 ATP1A2 ATP1A3

3.44e-0539716512CID000005839
Drugzopolrestat

NBN TGFB1 DECR1 LYVE1

4.10e-05271654CID000001613
DrugZK 114.043

CYP19A1 DECR1

5.22e-0521652CID006439372
DrugRanolazine

SCN5A SCN9A

5.22e-0521652DB00243
DrugSCH 10015

CYP19A1 DECR1

5.22e-0521652CID000014703
DrugAC1L4QG7

CYP19A1 DECR1

5.22e-0521652CID000161972
DrugFlecainide

SCN4A SCN5A

5.22e-0521652DB01195
Drug3-(5-methyl-2-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)propionic acid

FLT1 KDR

5.22e-0521652ctd:C477639
Drug7-batdo

CYP19A1 DECR1

5.22e-0521652CID000125502
Drug7-peatdo

CYP19A1 DECR1

5.22e-0521652CID000125503
Drugmu-conotoxin KIIIA, Conus kinoshitai

SCN2A SCN4A

5.22e-0521652ctd:C502265
Drugandrost-4-ene-3,6-dione

CYP19A1 DECR1

5.22e-0521652CID000585173
DrugProcainamide

SCN5A DNMT1

5.22e-0521652DB01035
Drug7-patdo

CYP19A1 DECR1

5.22e-0521652CID000131426
DrugNSC7524

TGFB1 SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3

5.64e-051821658CID000005657
Drugmesyl chloride

FLT1 NBN PPARA

5.91e-05111653CID000031297
Drugoxcarbazepine

PTPRU SCN4A SCN5A SCN9A

6.29e-05301654CID000034312
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

1.04e-1071645DOID:0060178 (implicated_via_orthology)
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

3.83e-09121645DOID:863 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN2A SCN4A SCN5A SCN9A

1.88e-07101644DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN2A SCN4A SCN5A SCN9A

1.88e-07101644DOID:0080422 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN2A SCN4A SCN5A SCN9A ATP1A1 ATP1A2 ATP1A3 ATP12A ATP1A4

3.50e-071631649DOID:1826 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN2A SCN4A SCN5A SCN9A

4.40e-07121644DOID:0060170 (implicated_via_orthology)
DiseaseBipolar Disorder

PSEN2 HTR4 ABCA13 WFS1 GRM3 PTGDS RFX4 TGFB1 SCN2A ATP1A1 ATP1A2 ATP1A3 DNAH8 DNMT1

5.00e-0747716414C0005586
Diseaseabdominal adipose tissue measurement

ZC3H11B SCN4A ATP1A1 ATP1A3 ATP1A4

1.15e-05531645EFO_0803316
Diseaserefractive error, age at onset, Myopia

FLT1 ADAMTSL1 TDRD9 ZC3H11B LRRC4C GRM3 GALNT18 ARID2

1.32e-051931648EFO_0004847, HP_0000545, MONDO_0004892
DiseaseALTERNATING HEMIPLEGIA OF CHILDHOOD 1

ATP1A2 ATP1A3

3.07e-0521642C3549447
Diseasealternating hemiplegia of childhood (is_implicated_in)

ATP1A2 ATP1A3

3.07e-0521642DOID:0050635 (is_implicated_in)
DiseaseNeoplasm Metastasis

FLT1 CTU2 IL18 AXL CYP19A1 ELP3 TGFB1 PLAU

3.07e-052171648C0027627
DiseaseCiliopathies

EVC2 CFTR TSC1 BBS10 DNAH5 DNAH8

3.58e-051101646C4277690
DiseaseNodular glomerulosclerosis

AXL ELMO1 TGFB1 KDR

7.94e-05411644C0017667
DiseaseCYSTIC FIBROSIS

CFTR TGFB1

9.18e-0531642219700
DiseaseCystic fibrosis

CFTR TGFB1

9.18e-0531642cv:C0010674
Diseasecerebral cavernous malformation (is_marker_for)

FLT1 KDR

9.18e-0531642DOID:0060669 (is_marker_for)
Diseaseallergic contact dermatitis (is_marker_for)

FLT1 KDR

9.18e-0531642DOID:3042 (is_marker_for)
Diseasearteriovenous malformations of the brain (is_marker_for)

FLT1 KDR

9.18e-0531642DOID:0060688 (is_marker_for)
Diseasechronic obstructive pulmonary disease (implicated_via_orthology)

TGFB1 PLAU

9.18e-0531642DOID:3083 (implicated_via_orthology)
DiseaseProteinuria

NCK1 PPARA TGFB1 NCK2

9.59e-05431644C0033687
DiseaseDiabetic Nephropathy

AXL ELMO1 TGFB1 KDR

1.05e-04441644C0011881
Diseasepsoriasis (is_marker_for)

FLT1 IL18 TGFB1 KDR

1.05e-04441644DOID:8893 (is_marker_for)
DiseaseUremia

FLT1 TGFB1 KDR

1.08e-04171643C0041948
Diseasealcohol use disorder (implicated_via_orthology)

SSH1 ARID2 SSH2 ATP1A1 ATP1A2 ATP1A3 ATP1A4

1.15e-041951647DOID:1574 (implicated_via_orthology)
DiseaseAlternating hemiplegia of childhood

ATP1A2 ATP1A3

1.83e-0441642C0338488
DiseaseHypokalemic periodic paralysis

SCN4A ATP1A2

1.83e-0441642C0238358
Diseasestatus epilepticus (implicated_via_orthology)

IL18 AQP4 PLAU

2.08e-04211643DOID:1824 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease (is_marker_for)

FLT1 IL18 TGFB1 KDR PLAU

2.13e-04971645DOID:3083 (is_marker_for)
DiseaseAcute Cerebrovascular Accidents

HTR4 RGS7 TGFB1 PLAU

2.34e-04541644C0751956
Diseaselung disease (is_implicated_in)

IL18 CFTR TGFB1

2.40e-04221643DOID:850 (is_implicated_in)
DiseaseHereditary Sensory Autonomic Neuropathy, Type 2

SCN9A DNMT1

3.04e-0451642C0020072
DiseaseEpilepsy

TSC1 TGFB1 SCN2A SCN9A DNM1

3.66e-041091645C0014544
DiseaseCerebrovascular accident

HTR4 RGS7 TGFB1 PLAU

3.99e-04621644C0038454
Diseasecystic fibrosis (is_marker_for)

IL18 CFTR PPARA TGFB1

3.99e-04621644DOID:1485 (is_marker_for)
DiseaseNephrotic Syndrome

NCK1 TGFB1 NCK2

4.47e-04271643C0027726
DiseaseEncephalopathies

TSC1 TGFB1 ATP1A2

4.47e-04271643C0085584
Diseasehydrocephalus (biomarker_via_orthology)

PPARA AQP4

4.54e-0461642DOID:10908 (biomarker_via_orthology)
DiseaseSensory Neuropathy, Hereditary

SCN9A DNMT1

4.54e-0461642C0699739
DiseaseFamilial benign neonatal epilepsy

SCN2A ATP1A2

4.54e-0461642C0220669
DiseaseCarcinoma, Granular Cell

CYP19A1 TGFB1 KDR PLAU DNMT1

4.87e-041161645C0205644
DiseaseAdenocarcinoma, Tubular

CYP19A1 TGFB1 KDR PLAU DNMT1

4.87e-041161645C0205645
DiseaseAdenocarcinoma, Oxyphilic

CYP19A1 TGFB1 KDR PLAU DNMT1

4.87e-041161645C0205642
DiseaseCarcinoma, Cribriform

CYP19A1 TGFB1 KDR PLAU DNMT1

4.87e-041161645C0205643
DiseaseAdenocarcinoma, Basal Cell

CYP19A1 TGFB1 KDR PLAU DNMT1

4.87e-041161645C0205641
DiseaseAdenocarcinoma

CYP19A1 TGFB1 KDR PLAU DNMT1

4.87e-041161645C0001418
DiseaseCerebral Hemorrhage

FLT1 KDR PLAU

4.99e-04281643C2937358
DiseaseColorectal Carcinoma

EVC2 MAP1B ABCA13 CFTR PTPRU LRRC4 TGFB1 MLH3 MYLK3 GUCY2C KDR DNAH8

5.86e-0470216412C0009402
DiseaseNeoplasm Invasiveness

CTU2 AXL ELP3 TGFB1 PLAU DNMT1

5.92e-041841646C0027626
Diseasebreast cancer (is_marker_for)

IL18 NBN TSC1 TGFB1 KDR PLAU

6.09e-041851646DOID:1612 (is_marker_for)
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN9A DNMT1

6.33e-0471642C0020075
DiseaseEarly-onset autosomal dominant Alzheimer disease

PSEN2 PLAU

6.33e-0471642cv:CN043596
DiseaseProstatic Neoplasms

RAG1 IL18 CYP19A1 NBN PPARA TGFB1 SF3B1 ARID2 PLAU POLK DNMT1

6.95e-0461616411C0033578
DiseaseMalignant neoplasm of prostate

RAG1 IL18 CYP19A1 NBN PPARA TGFB1 SF3B1 ARID2 PLAU POLK DNMT1

6.95e-0461616411C0376358
DiseaseSarcoidosis

IL18 TGFB1

8.41e-0481642C0036202
DiseaseAlzheimer disease

PSEN2 PLAU

8.41e-0481642cv:C0002395
DiseaseX-linked infantile spasms

CAMK2G DNM1

8.41e-0481642C4552072
Diseasesensorineural hearing loss (biomarker_via_orthology)

PTGDS ATP1A1

8.41e-0481642DOID:10003 (biomarker_via_orthology)
Diseaseliver cirrhosis (biomarker_via_orthology)

FLT1 LBP DNMT1

8.89e-04341643DOID:5082 (biomarker_via_orthology)
Diseaseaxial length measurement

ZC3H11B LRRC4C CMSS1 ZNF469

9.08e-04771644EFO_0005318
Diseasecorneal resistance factor

ADAMTS19 ARHGEF12 FBXL17 ZC3H11B CCDC80 ZNF106 ZNF469 ST6GALNAC3 SLC25A15

9.90e-044511649EFO_0010067
DiseaseAsthma

TGFB1 PLAU DNAH5 DNMT1

1.05e-03801644C0004096
Diseasepulmonary sarcoidosis (is_implicated_in)

CFTR TGFB1

1.08e-0391642DOID:13406 (is_implicated_in)
DiseasePulmonary Cystic Fibrosis

CFTR TGFB1

1.08e-0391642C0392164
DiseaseFibrocystic Disease of Pancreas

CFTR TGFB1

1.08e-0391642C1527396
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN2A SCN9A

1.08e-0391642C3502809
Diseaseotosclerosis

ZC3H11B TGFB1 KDR DNMT1

1.10e-03811644EFO_0004213
Diseasevisceral heterotaxy (implicated_via_orthology)

DRC1 OSBPL1A DNAH5

1.14e-03371643DOID:0050545 (implicated_via_orthology)
DiseaseEpilepsy, Cryptogenic

TSC1 TGFB1 SCN2A DNM1

1.15e-03821644C0086237
DiseaseAwakening Epilepsy

TSC1 TGFB1 SCN2A DNM1

1.15e-03821644C0751111
DiseaseAura

TSC1 TGFB1 SCN2A DNM1

1.15e-03821644C0236018
DiseaseSchizophrenia

IPO5 IL18 PSEN2 HTR4 ABCA13 PPARA GRM3 AQP4 TGFB1 ADAMTS12 KDR DNM1 DNMT1

1.37e-0388316413C0036341
Diseasecups of coffee per day measurement

ATP1A1 ATP1A3 ATP1A4

1.43e-03401643EFO_0006782
Diseaseamino acid measurement

IPO5 PIGN ADAMTS19 GLS2 CAMK2G MCCC1 SYT10 GUCY2C SCN4A DNM1 WNK2

1.50e-0367816411EFO_0005134
Diseasebreast cancer (is_implicated_in)

IL18 PSEN2 CYP19A1 NBN TGFB1

1.54e-031501645DOID:1612 (is_implicated_in)
DiseasePR domain zinc finger protein 1 measurement

MED16 LBP

1.63e-03111642EFO_0801904
DiseaseAshkenazi Jewish disorders

CFTR TGFB1

1.63e-03111642cv:CN118946
DiseaseCystic Fibrosis

CFTR TGFB1

1.63e-03111642C0010674
Diseasehigh grade glioma (is_marker_for)

ASPM KDR PLAU

1.65e-03421643DOID:3070 (is_marker_for)
Diseasehypertension (biomarker_via_orthology)

CYP19A1 PPARA AQP4 TGFB1 KDR ATP1A2

1.74e-032271646DOID:10763 (biomarker_via_orthology)
DiseaseIschemic stroke, coronary artery disease

SORBS2 HTR4 TMEM132D NLRP5

1.76e-03921644EFO_0001645, HP_0002140
Diseasecentral corneal thickness

ADAMTS19 FBXL17 ZC3H11B CCDC80 ZNF106 ZNF469 ST6GALNAC3

1.77e-033091647EFO_0005213
Diseasepulmonary fibrosis (implicated_via_orthology)

TGFB1 PLAU

1.95e-03121642DOID:3770 (implicated_via_orthology)
Diseaseretinopathy of prematurity (biomarker_via_orthology)

FLT1 KDR

1.95e-03121642DOID:13025 (biomarker_via_orthology)
Diseasehyperhomocysteinemia (biomarker_via_orthology)

ATP1A1 ATP1A2

1.95e-03121642DOID:9279 (biomarker_via_orthology)
DiseaseSudden infant death syndrome

AQP4 SCN5A

1.95e-03121642C0038644
Diseasethyroid gland carcinoma (is_marker_for)

FLT1 KDR

1.95e-03121642DOID:3963 (is_marker_for)
Diseasemacular retinal edema (is_marker_for)

FLT1 KDR

1.95e-03121642DOID:4449 (is_marker_for)
Diseaseresponse to hydrochlorothiazide, fasting blood glucose measurement

CYP19A1 ZNF106 OTOGL

2.15e-03461643EFO_0004465, EFO_0005202
Diseasehearing impairment

MYO1A WFS1 PJVK DNMT1

2.21e-03981644C1384666
Diseasemyocardial infarction (is_implicated_in)

PPARA TGFB1 KDR PLAU

2.30e-03991644DOID:5844 (is_implicated_in)
DiseaseInfantile Severe Myoclonic Epilepsy

SCN2A SCN9A

2.30e-03131642C0751122
Diseaseautoimmune thrombocytopenic purpura (is_marker_for)

IL18 TGFB1

2.30e-03131642DOID:8924 (is_marker_for)
Diseaseaplastic anemia (is_implicated_in)

NBN TGFB1

2.30e-03131642DOID:12449 (is_implicated_in)
Diseaseillegal drug consumption

SYT6 TMEM132D

2.30e-03131642EFO_0005431
Diseaseesophageal adenocarcinoma, Barrett's esophagus, sex interaction measurement

CFTR CEP72

2.30e-03131642EFO_0000280, EFO_0000478, EFO_0008343
DiseasePancreatic Neoplasm

AXL TGFB1 KDR PLAU

2.38e-031001644C0030297
Diseaseserum metabolite measurement

ADAMTSL1 SORBS2 GLS2 PSEN2 KIF26B SYT6 ERMP1 MCCC1 PGK2 ST6GALNAC3 FAM222A DNAH17 DNMT1

2.48e-0394516413EFO_0005653
DiseaseMood Disorders

HTR4 WFS1 GRM3 TGFB1 DNMT1

2.53e-031681645C0525045
DiseaseMalignant neoplasm of pancreas

AXL TGFB1 KDR PLAU

2.56e-031021644C0346647

Protein segments in the cluster

PeptideGeneStartEntry
TVAMVCTRKISIAKS

AQP4

101

P55087
KSLELRKCEAVASAM

FAM222A

21

Q5U5X8
SSIELTKMLCEILKV

ELMO1

416

Q92556
VCKLMANKTRILVTS

CFTR

591

P13569
EIKLCMLAKARESAS

DNMT1

1591

P26358
ELCRQMTKTISEVIK

DYNLT5

101

Q8N7M0
VILKCNVKDSSMLIS

GRM3

726

Q14832
IAKVEKSIDMLVCLV

ARID2

436

Q68CP9
SEKKSVLMLIICSSA

CMSS1

151

Q9BQ75
ESSRMEITRKVVCII

ABCA13

1876

Q86UQ4
RAKCTEALAKQSLVM

CEP72

176

Q9P209
RMIVDCVSSHLKKTG

BBS10

66

Q8TAM1
KSTKKTMLTLTLVCA

ERMP1

646

Q7Z2K6
IQKAFCRMVTRKLET

ASPM

2821

Q8IZT6
VRLKDICSMTKEKTA

GRAMD1B

151

Q3KR37
TLKAMKKCSVPTVRA

ADAMTS12

1551

P58397
LESFCKMATRKISVI

CCDC80

646

Q76M96
LICRMAASVKEQSTK

ARHGEF12

1126

Q9NZN5
VVKVVKTLLLRMGCS

MROH7

906

Q68CQ1
MDEIVKATSKGCITV

PGK2

356

P07205
FARKLMTKETVDAVC

RAG1

856

P15918
LDTMVDRCVVKVAAK

RFX4

401

Q33E94
RKTTVSCTKIMSKNI

ADAMTS19

936

Q8TE59
KSTNCVVDSRMVVKI

GUCY2C

616

P25092
LAKSMIISVSECKIQ

OR5H8

86

P0DN80
FLCTKRKMAQAVTLT

LDLRAP1

146

Q5SW96
MKLSTRFTCTVNRIK

AP1G1

531

O43747
LISEKKAISMTGCIL

OR6K3

101

Q8NGY3
MKKFIRCSTRVTVGT

PCGF5

161

Q86SE9
KVLESRICEMIQKSV

LBP

191

P18428
IKVMTTRILSVKTEF

LINS1

96

Q8NG48
NIKMKRSIEEACFTL

MAP1B

371

P46821
RKKLICVTEVFMETS

LYVE1

196

Q9Y5Y7
KARKLSTECAFMTIE

KIAA0825

1091

Q8IV33
SLIKGTKVIVMEKCS

NCK1

126

P16333
SLVKGSRVTVMEKCS

NCK2

131

O43639
VLSVTRSCMTDAKKL

GGNBP2

121

Q9H3C7
ALCSRTMETAKEKVV

MYO1A

316

Q9UBC5
CSKLEKADVLEMTVR

HES2

51

Q9Y543
KCVDMVISELISTVR

DNM1

426

Q05193
DAVTKCRSAGIKVIM

ATP12A

616

P54707
TVCLTLTAKRMARKN

ATP1A1

341

P05023
VKVMLRICSTLARDT

KIF26B

451

Q2KJY2
STVRPVAVLKKSLCM

LENG8

571

Q96PV6
KSSCVKLQVEMVGLT

DDX60

631

Q8IY21
EGTQTRSAICRKMLK

ADAMTSL1

806

Q8N6G6
RSAICRKMLKTGLST

ADAMTSL1

811

Q8N6G6
AVSCSVIESKKTVME

HTD2

141

P86397
KMQSSLKLVDCIIEV

MTG1

41

Q9BT17
MIKCLSVEVQAKLRS

MLH3

1

Q9UHC1
FVSRLLVKEKSCRMS

MYLK3

746

Q32MK0
CKRLEKITEMITVVQ

DNAH8

366

Q96JB1
MERVTKSADACLTTI

NIPBL

1301

Q6KC79
IAVRTKAMKCLSEVV

NIPBL

1786

Q6KC79
VRMIVDVSKAACILT

DIP2B

1091

Q9P265
MVALTAECDLETRKK

EVC2

451

Q86UK5
ASCSRVSKVMILVKA

MYCLP1

306

P12525
EVMKTTKIIIGCFVA

LRRC4

521

Q9HBW1
AIVVSSLIKMDCNKA

GLS2

271

Q9UI32
DRSLTCTSAVEIMKK

RPS6KA5

626

O75582
EVMKTTKIIIGCFVA

LRRC4C

521

Q9HCJ2
VTCSSMVLKTLTKPV

LPAR6

201

P43657
SILTERAMKTLCAKL

NLRP5

791

P59047
VMVITCFIFKKTVRD

DPY19L2

501

Q6NUT2
TQSSMRKKVCDIAAE

IPO5

101

O00410
SILRKCIGMELSKIT

OSBPL1A

551

Q9BXW6
LLVSVTSKGVVTCMR

EXOSC7

226

Q15024
CMAAKSLTIVVVAKV

GPR151

121

Q8TDV0
QISEKTTKRILMLLC

DRC1

486

Q96MC2
VLSTRILAMKASLCK

MED16

521

Q9Y2X0
TRAKTLVMLTQCFEK

PTPRQ

2126

Q9UMZ3
CSSIVMITKLVEVGR

PTPRU

981

Q92729
MITKLVEVGRVKCSR

PTPRU

986

Q92729
CVIASRKMDVLKATA

DECR1

86

Q16698
ATVTVCLTLTAKRMA

ATP1A2

336

P50993
KLNCMTKIVESTLFR

DOCK5

856

Q9H7D0
TIASLQMEVCRLKKE

CEP70

171

Q8NHQ1
GLVRMVTVCAESLKT

CYP19A1

156

P11511
CLSVEVTKKNREDMT

DNAH17

4351

Q9UFH2
IEKAMISCRKIAESS

FNIP2

351

Q9P278
KIKTSRVFIRDCSMV

DHX57

1286

Q6P158
ETVMEIVKRCKNLSS

FBXL17

556

Q9UF56
MVCTRKTKTLVSTCV

GALNT18

1

Q6P9A2
RAIIFCETKKNVTEM

DDX50

391

Q9BQ39
RELITKTKMQTEEVC

DENND4C

941

Q5VZ89
MRTETKAAKTLCIIM

HTR4

251

Q13639
KFAVMEEKTILSCIL

CYP4V2

471

Q6ZWL3
IRTASGIAVVAVMCK

ELP3

81

Q9H9T3
ACRVMRTAKKLGVQT

MCCC1

61

Q96RQ3
TVCLTLTAKRMARKN

ATP1A3

331

P13637
TVKMIVEVSKSACVL

DIP2A

1086

Q14689
MAVTISVKCEKISTL

IL18

96

Q14116
KVMTGDSCTRLAIKL

CTU2

261

Q2VPK5
NCRSDTVMEKRSFKV

HMCES

96

Q96FZ2
CSSAMRKQEIIKITE

CAMK2G

421

Q13555
IINSTKKEVITSMDC

DNAH5

1126

Q8TE73
VMKTTKIIIGCFVAI

LRRC4B

571

Q9NT99
VIIKSVIRKQDCMSQ

OTOGL

2271

Q3ZCN5
KIERSKIVSTMRCKT

PPEF2

306

O14830
KIVSTMRCKTRQKSE

PPEF2

311

O14830
MSVVKLSCASIKVNV

OR52N5

191

Q8NH56
TLCMAEKTLVAKLVA

PPARA

246

Q07869
RKTLASVIIMEKATT

MROH2A

61

A6NES4
KRSADSELKALVCMA

RUNDC1

531

Q96C34
TVIKCRNLKAMDITG

SYT6

381

Q5T7P8
SAIKEMCVATRKTRT

MEIOC

886

A2RUB1
CVNTTEVDIKKSSRM

RGS7

206

P49802
INRCEKVKTMEVTSV

TRIM39

296

Q9HCM9
QLKMTVVKLISHREC

PLAU

331

P00749
LVLVCKSVKPAMITS

RPP38

131

P78345
SVKKLSDVMILTVFC

SCN4A

246

P35499
LVKVEMVISESCQKS

TMEM132D

766

Q14C87
MVISESCQKSKRKSV

TMEM132D

771

Q14C87
VKVVLMSATISCKEF

TDRD9

281

Q8NDG6
VMVSVKVTIKTICAL

NBN

151

O60934
TLAKMRVHISSCLKV

RNF166

106

Q96A37
EIAEIMLSKKVSRCF

SAMD9L

1286

Q8IVG5
VCSVVSTNLKMVSKR

IL1RAPL2

11

Q9NP60
NMIAKLAKTCTLRIS

HUS1

21

O60921
REKKAALSMCKSVVA

PTGDS

56

P41222
SVKKLADVMVLTVFC

SCN5A

246

Q14524
SVKKLSDVMILTVFC

SCN9A

241

Q15858
MACILKRKSVIAVSF

ST6GALNAC3

1

Q8NDV1
EKKTITRMVTQINCE

SHOC1

21

Q5VXU9
MITSVAVELCKNVKL

ST8SIA6

326

P61647
LTVACIFRGKMSTKE

TUBB1

311

Q9H4B7
VMCLKDLTSIVDIKT

MYCBP2

3736

O75592
TSIEEKMTAARIRKC

RNF216

661

Q9NWF9
KTCISRAMKITTVNS

RNF169

561

Q8NCN4
DCIKSRIQVLSMSGK

SLC25A15

231

Q9Y619
STDQEMSKCKISIRR

SYT14P1

96

Q58G82
RKDLMNSEVICSVKS

SORBS2

461

O94875
GLVKSCSETLLRVMT

RRP12

321

Q5JTH9
SKESKSCTIGMVLRL

SSH1

131

Q8WYL5
TCNAMSRKLDKLTVL

ARNTL

101

O00327
ATVTVCLTLTAKRMA

ATP1A4

346

Q13733
ILVVMSILASKGCIK

CLEC2L

81

P0C7M8
SKQCKDVSRLRSVLM

CLTB

206

P09497
SLKACKREIKSVMNT

CNOT10

231

Q9H9A5
RSIKIAMTTCEQIVR

CNOT1

1411

A5YKK6
CRSSTPIEMAVKEKI

CTPS2

216

Q9NRF8
LLKCLKMDTDVVVLT

TSC1

116

Q92574
CRVKKTTMATRKVIV

VSIG8

126

P0DPA2
QMTDVISVCKTFIKS

ZBTB8A

106

Q96BR9
KTQTSAFSRIMKLCE

USP45

156

Q70EL2
LTMSAVVKKVADRLT

POLR3C

116

Q9BUI4
SRKAVLCVVMESIRT

PJVK

151

Q0ZLH3
LRKVNMEKSVTVLCT

SSH2

1041

Q76I76
SCSLVGMKVLQKVTR

SPIDR

546

Q14159
AADLISRTAVVMKTC

SF3B1

951

O75533
SRTAVVMKTCQEEKL

SF3B1

956

O75533
STCKTIDMELVKRKR

TGFB1

31

P01137
TEKMLKALGIITCTE

POLK

361

Q9UBT6
KKLSDVMILTVFCLS

SCN2A

246

Q99250
DTGAMAVLALTCVKK

TCN1

186

P20061
AVVVTKEMKRHCTVS

WDFY4

1166

Q6ZS81
VKTMKIAICTRSELE

AXL

566

P30530
TLCMIVVVATIKSVR

PSEN2

96

P49810
ITKTGKRIMLECSQT

TRBV24-1

31

A0A075B6N3
SKKTILMVTNRRVLC

VPS13C

3641

Q709C8
SVRDKCVEMLSAALK

TCEA3

186

O75764
SLCVVTSLMKRKDSF

PIGN

631

O95427
TLTVIKCRNLKAMDI

SYT10

381

Q6XYQ8
ITKIQVKRCEIMRET

ZC3H11B

551

A0A1B0GTU1
VLLEKCKGSRAAMSL

ZNF469

2006

Q96JG9
VVKCPMVTSDIAQRK

ZNF644

551

Q9H582
IDKTATCRTVAVKML

KDR

856

P35968
TCRTVAVKMLKEGAT

KDR

861

P35968
IGCMQTRASVKLVKT

TMEM129

286

A0AVI4
KGKRCIVLVTELMTS

WNK2

266

Q9Y3S1
KSPTCRTVAVKMLKE

FLT1

851

P17948
SKISRDSEFRMTVKC

ZP2

451

Q05996
KTILCMKVVNDLVFS

ZNF106

1701

Q9H2Y7
IMSELRTIKKAICTG

WWC3

146

Q9ULE0
TCRISESVKKLMELA

ZW10

476

O43264
TVSKIDTEMRKRLCG

ATP6V0D2

66

Q8N8Y2
SMVICTLKVFQDSKA

WFS1

356

O76024