Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	mandibular cyst	ENAM PTCH1	2.84e-05	2	75	2	MP:0030220
MousePheno	jaw cyst	ENAM PTCH1	2.84e-05	2	75	2	MP:0030219
Domain	HMGI/Y_DNA-bd_CS	PRR12 PRB1 PRB3 PRB2 PLEKHA4	3.38e-07	31	89	5	IPR000637
Domain	Collagen	COL4A5 COL12A1 COL17A1 COL26A1	7.27e-04	85	89	4	IPR008160
Domain	Collagen	COL4A5 COL12A1 COL17A1 COL26A1	7.27e-04	85	89	4	PF01391
Domain	Inhibin_asu	BMP8B BMP8A	1.69e-03	13	89	2	IPR002405
Domain	WH2	WIPF1 WIPF2	1.97e-03	14	89	2	SM00246
Domain	WH2	WIPF1 WIPF2	2.58e-03	16	89	2	PF02205
Domain	RRM	RBM33 CPSF6 SCAF8 GRSF1 CSTF2T	3.81e-03	217	89	5	SM00360
Domain	WH2_dom	WIPF1 WIPF2	4.45e-03	21	89	2	IPR003124
Domain	RRM_dom	RBM33 CPSF6 SCAF8 GRSF1 CSTF2T	4.61e-03	227	89	5	IPR000504
Domain	PH	SPTBN4 ACAP1 PLEKHA4 PHLPP1 DNM2	4.78e-03	229	89	5	PF00169
Domain	RRM	RBM33 CPSF6 SCAF8 GRSF1 CSTF2T	4.87e-03	230	89	5	PS50102
Domain	EPHD	KMT2D TCF20	4.87e-03	22	89	2	PS51805
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A5 COL12A1 COL17A1 COL26A1	5.20e-05	41	71	4	MM15538
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A5 COL12A1 COL17A1 COL26A1	6.89e-05	44	71	4	M27812
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A5 COL12A1 COL17A1 COL26A1	2.48e-04	61	71	4	MM14637
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A5 COL12A1 COL17A1 COL26A1	2.99e-04	64	71	4	M26953
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A5 COL12A1 COL17A1 COL26A1	3.56e-04	67	71	4	M26999
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PRR12 ATXN2L TTF2 KMT2D WIZ TCF20 WIPF1 RBM33 CPSF6 BAG1 ZNF207 TAF4 EDC4 RFX5 CSTF2T PRRC2B DNM2 FOSL1	3.33e-10	1103	89	18	34189442
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PRR12 KMT2D WIZ PYGO2 TCF20 RBM33 CPSF6 MEPCE RFX5 PRRC2B	1.86e-09	268	89	10	33640491
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TAOK2 SEMA6C UNC119 KCTD12 PRR12 COL4A5 BMP8B KMT2D WIZ CELSR2 ZNF500 RELB EDC4 PTCH1 RASSF7 PRRC2B RAB11FIP3	2.67e-09	1105	89	17	35748872
Pubmed	The involvement of proline-rich protein Mus musculus predicted gene 4736 in ocular surface functions.	PRB1 PRB3 PRB2	6.47e-08	4	89	3	27588265
Pubmed	Length polymorphisms in human proline-rich protein genes generated by intragenic unequal crossing over.	PRB1 PRB3 PRB2	6.47e-08	4	89	3	2851479
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	PRR12 ATXN2L TROAP RBM33 CPSF6 CCDC120 PRRC2B	1.35e-07	152	89	7	38360978
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	KCTD12 PRR12 WIZ TCF20 RBM33 PCLO ZNF207 TAF4 RFX5 CSTF2T	1.44e-07	425	89	10	24999758
Pubmed	Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.	PRB1 PRB3 PRB2	3.22e-07	6	89	3	2993301
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TAOK2 SPTBN4 KCTD12 KIF13B WIZ TCF20 CELSR2 TAF4 EDC4 VIRMA SHANK3 PRRC2B DNM2	1.05e-06	963	89	13	28671696
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	PRR12 KMT2D PYGO2 TCF20 RBM33 CPSF6 SCAF8 ZNF207 PRRC2B	2.71e-06	457	89	9	32344865
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	TAOK2 KIF13B ATXN2L KMT2D WIZ TCF20 CPSF6 EDC4	2.79e-06	341	89	8	32971831
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	WIPF1 CPSF6 ZNF207 WIPF2 VIRMA DNM2	2.93e-06	154	89	6	16055720
Pubmed	Interaction network of human early embryonic transcription factors.	PRR12 KMT2D WIZ PYGO2 TCF20 TPRX1 TAF4 PRRC2B	3.45e-06	351	89	8	38297188
Pubmed	Rearrangement of the COL12A1 and COL4A5 genes in subungual exostosis: molecular cytogenetic delineation of the tumor-specific translocation t(X;6)(q13-14;q22).	COL4A5 COL12A1	6.48e-06	2	89	2	16284948
Pubmed	Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.	BMP8B BMP8A	6.48e-06	2	89	2	31940275
Pubmed	Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.	BMP8B BMP8A	6.48e-06	2	89	2	9463357
Pubmed	The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.	BMP8B BMP8A	6.48e-06	2	89	2	8682296
Pubmed	WIP and WICH/WIRE co-ordinately control invadopodium formation and maturation in human breast cancer cell invasion.	WIPF1 WIPF2	6.48e-06	2	89	2	27009365
Pubmed	Fractionation and characterization of basic proline-rich peptides of human parotid saliva and the amino acid sequence of proline-rich peptide P-E.	PRB1 PRB2	6.48e-06	2	89	2	7118863
Pubmed	Basic proline-rich proteins from human parotid saliva: complete covalent structure of protein IB-9 and partial structure of protein IB-6, members of a polymorphic pair.	PRB1 PRB2	6.48e-06	2	89	2	6924859
Pubmed	The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells.	BMP8B BMP8A	6.48e-06	2	89	2	21277400
Pubmed	Whole exome sequencing implicates PTCH1 and COL17A1 genes in ossification of the posterior longitudinal ligament of the cervical spine in Chinese patients.	COL17A1 PTCH1	6.48e-06	2	89	2	24668667
Pubmed	Clones from the human gene complex coding for salivary proline-rich proteins.	PRB1 PRB2	6.48e-06	2	89	2	6089212
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PRR12 TCF20 RBM33 CPSF6 SCAF8 CCDC120	7.20e-06	180	89	6	35198878
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	PRR12 ERFE KMT2D CPSF6 SCAF8 RFX5	8.16e-06	184	89	6	32908313
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ATXN2L TTF2 KMT2D WIZ TCF20 TAF4 EDC4 CSTF2T PRRC2B	1.18e-05	549	89	9	38280479
Pubmed	Molecular genetics of human salivary proteins and their polymorphisms.	PRB1 PRB3	1.94e-05	3	89	2	3055850
Pubmed	Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.	BMP8B BMP8A	1.94e-05	3	89	2	9076678
Pubmed	Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).	BMP8B BMP8A	1.94e-05	3	89	2	12925636
Pubmed	The structure and evolution of the human salivary proline-rich protein gene family.	PRB1 PRB2	1.94e-05	3	89	2	8422499
Pubmed	Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.	KMT2D PYGO2	1.94e-05	3	89	2	26902498
Pubmed	PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.	PAK4 RELB	1.94e-05	3	89	2	31399573
Pubmed	Alternative NF-κB signaling promotes colorectal tumorigenesis through transcriptionally upregulating Bcl-3.	RELB BCL3	1.94e-05	3	89	2	29973688
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	KMT2D PTCH1	1.94e-05	3	89	2	22183980
Pubmed	Requirement of Bmp8b for the generation of primordial germ cells in the mouse.	BMP8B BMP8A	1.94e-05	3	89	2	10894154
Pubmed	BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions.	BMP8B BMP8A	1.94e-05	3	89	2	22579288
Pubmed	Mutation in Bmp7 exacerbates the phenotype of Bmp8a mutants in spermatogenesis and epididymis.	BMP8B BMP8A	1.94e-05	3	89	2	11784057
Pubmed	Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a.	BMP8B BMP8A	1.94e-05	3	89	2	25451979
Pubmed	Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy.	KMT2D FAM174A SYN2 ZNF207 EDC4	2.81e-05	137	89	5	30862715
Pubmed	Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation.	RELB BCL3	3.87e-05	4	89	2	16081776
Pubmed	cDNA clones for mouse parotid proline-rich proteins. mRNA regulation by isoprenaline and the nucleotide sequence of proline-rich protein cDNA MP5.	PRB1 PRB3	3.87e-05	4	89	2	1339347
Pubmed	Characterization and chromosomal localization of PTPRO, a novel receptor protein tyrosine phosphatase, expressed in hematopoietic stem cells.	BMP8B BMP8A	3.87e-05	4	89	2	9434160
Pubmed	Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development.	BMP8B BMP8A	3.87e-05	4	89	2	8843393
Pubmed	FBP17 Mediates a Common Molecular Step in the Formation of Podosomes and Phagocytic Cups in Macrophages.	WIPF1 DNM2	3.87e-05	4	89	2	19155218
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	KCTD12 ATXN2L RBM33 CPSF6 MEPCE ZNF207 VIRMA GRSF1 CSTF2T PRRC2B	4.17e-05	807	89	10	22681889
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	PRR12 KMT2D WIZ TCF20	6.31e-05	83	89	4	28794006
Pubmed	Activation of nuclear factor-kappaB p50 homodimer/Bcl-3 complexes in nasopharyngeal carcinoma.	RELB BCL3	6.44e-05	5	89	2	14678988
Pubmed	Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice.	HJV ERFE	6.44e-05	5	89	2	29073189
Pubmed	Enteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assembly.	WIPF1 WIPF2	6.44e-05	5	89	2	22966049
Pubmed	Identification of erythroferrone as an erythroid regulator of iron metabolism.	HJV ERFE	6.44e-05	5	89	2	24880340
Pubmed	The intriguing heterogeneity of human salivary proline-rich proteins: Short title: Salivary proline-rich protein species.	PRB3 PRB2	6.44e-05	5	89	2	26375204
Pubmed	Despite inhibition of nuclear localization of NF-kappa B p65, c-Rel, and RelB, 17-beta estradiol up-regulates NF-kappa B signaling in mouse splenocytes: the potential role of Bcl-3.	RELB BCL3	6.44e-05	5	89	2	17641044
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	UNC119 TNK1 KIF13B ATXN2L TCF20 PAK4 MEPCE EDC4 VIRMA RASSF7	7.15e-05	861	89	10	36931259
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	PRR12 TTF2 KMT2D WIZ TCF20 PCLO ADNP2	7.50e-05	398	89	7	35016035
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PCLO ADNP2 PHLPP1 RAB11FIP3	7.58e-05	87	89	4	12465718
Pubmed	Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation.	BMP8B BMP8A	9.65e-05	6	89	2	9878243
Pubmed	Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development.	BMP8B BMP8A	9.65e-05	6	89	2	7605753
Pubmed	Trophoblast giant cells express NF-kappa B2 during early mouse development.	RELB BCL3	9.65e-05	6	89	2	10402669
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TAOK2 PRR12 WIZ RBM33 CPSF6 SCAF8 MED25 ZNF207 TAF4 EDC4 VIRMA GRSF1 CSTF2T	1.10e-04	1497	89	13	31527615
Pubmed	USP1 deubiquitinates Akt to inhibit PI3K-Akt-FoxO signaling in muscle during prolonged starvation.	OTUD5 PHLPP1 PROB1	1.18e-04	37	89	3	32133736
Pubmed	Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.	KMT2D RELB	1.35e-04	7	89	2	19219072
Pubmed	The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4.	BMP8B BMP8A	1.35e-04	7	89	2	9070944
Pubmed	Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat.	BMP8B BMP8A	1.35e-04	7	89	2	12107726
Pubmed	Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.	CELSR2 EDC4 DNM2	1.38e-04	39	89	3	21347282
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	KCTD12 ATXN2L TTF2 WIZ CPSF6 PAK4 MEPCE EDC4 PRRC2B DNM2	1.39e-04	934	89	10	33916271
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	CELSR2 TROAP SCAF8 MEPCE CCDC120 PRRC2B	1.42e-04	307	89	6	37499664
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TAOK2 KCTD12 ATXN2L CELSR2 WFS1 CPSF6 PCLO SYN2 PLPPR3 EDC4 SHANK3	1.57e-04	1139	89	11	36417873
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PCLO ZNF500 PHLPP1 PRRC2B	1.57e-04	105	89	4	9628581
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	PRR12 TCF20 OTUD5 CPSF6 MED25 ZNF207 PPP1R13L	1.67e-04	453	89	7	29656893
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	WIPF1 CPSF6 WIPF2 DNM2	1.95e-04	111	89	4	22558309
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	CBX6 SCAF8 PAK4 PLEKHA4 ZNF207 PRRC2B	2.06e-04	329	89	6	34316702
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	ACAP1 BMP8B WIPF1 CELSR2 SHANK3 DNM2	2.06e-04	329	89	6	17474147
Pubmed	Gene structure and evolution of testicular haploid germ cell-specific genes, Oxct2a and Oxct2b.	BMP8B BMP8A	2.30e-04	9	89	2	15028287
Pubmed	Collagen XXVII organises the pericellular matrix in the growth plate.	COL17A1 PTCH1	2.30e-04	9	89	2	22206015
Pubmed	Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis.	BMP8B BMP8A	2.30e-04	9	89	2	1460021
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	OTUD5 ADNP2 TAF4 PRRC2B	2.31e-04	116	89	4	30804394
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	PCLO PLPPR3 PPP1R13L NYAP1 PRRC2B	2.50e-04	218	89	5	33378226
Pubmed	Human transcription factor protein interaction networks.	PRR12 KMT2D WIZ PYGO2 TCF20 RBM33 SCAF8 RELB TAF4 EDC4 RFX5 PRRC2B	2.82e-04	1429	89	12	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SPTBN4 KCTD12 ATXN2L SNPH WFS1 PCLO SYN2 EDC4 VIRMA SHANK3 PRRC2B DNM2	2.86e-04	1431	89	12	37142655
Pubmed	Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies.	TCF20 WFS1	2.88e-04	10	89	2	19082521
Pubmed	Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.	TCF20 WFS1	2.88e-04	10	89	2	20509872
Pubmed	Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.	KMT2D PYGO2	2.88e-04	10	89	2	20937768
Pubmed	CCND2, CTNNB1, DDX3X, GLI2, SMARCA4, MYC, MYCN, PTCH1, TP53, and MLL2 gene variants and risk of childhood medulloblastoma.	KMT2D PTCH1	2.88e-04	10	89	2	26290144
Pubmed	Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.	RELB EDC4	3.51e-04	11	89	2	23583643
Pubmed	Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.	BMP8B BMP8A	3.51e-04	11	89	2	10721728
Pubmed	PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion.	DMRT2 PRB1 PAK4 DNM2	3.56e-04	130	89	4	26598620
Pubmed	Common type 2 diabetes risk gene variants associate with gestational diabetes.	TCF20 WFS1	4.96e-04	13	89	2	18984664
Pubmed	PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum.	SYN2 GRIN2C	4.96e-04	13	89	2	29056747
Pubmed	Bmp7 regulates germ cell proliferation in mouse fetal gonads.	BMP8B BMP8A	4.96e-04	13	89	2	18391523
Pubmed	Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.	COL4A5 ADAM19 COL17A1	5.49e-04	62	89	3	28344315
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	KCTD12 RBM33 PAK4 ZNF207 PPP1R13L WIPF2 VIRMA GRSF1 DNM2	5.68e-04	916	89	9	32203420
Pubmed	New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.	BMP8B BMP8A	5.78e-04	14	89	2	11526197
Pubmed	Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.	XYLT1 PTCH1	5.78e-04	14	89	2	19666503
Pubmed	Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.	OTUD5 CCDC120	5.78e-04	14	89	2	11138001
Pubmed	A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.	ENAM PYGO2	5.78e-04	14	89	2	28174279
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SPTBN4 ATXN2L PLEKHA4 EDC4 PPP1R13L SHANK3 DNM2	5.96e-04	560	89	7	21653829
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	ATXN2L TCF20 SCAF8 MEPCE PPP1R13L PRRC2B	6.03e-04	403	89	6	35253629
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CAMKK2 SNPH TCF20 SCAF8 VIRMA PRRC2B	6.35e-04	407	89	6	12693553
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TTF2 WIZ CPSF6 SCAF8 PAK4 EDC4 DNM2	7.48e-04	582	89	7	20467437
Pubmed	Deletion of Lrp4 increases the incidence of microphthalmia.	BMP8B BMP8A PTCH1	7.51e-04	69	89	3	30352686
Interaction	ALG13 interactions	PRR12 KMT2D TCF20 RBM33 CPSF6 SCAF8 GRSF1 PRRC2B	1.37e-06	183	88	8	int:ALG13
Interaction	BAG2 interactions	KIF13B TTF2 WIZ TCF20 RBM33 OTUD5 PLEKHA4 PHLPP1 BCL3 EDC4 PPP1R13L VIRMA CSTF2T	2.92e-06	622	88	13	int:BAG2
Interaction	TOP3B interactions	TAOK2 SEMA6C UNC119 KCTD12 PRR12 COL4A5 BMP8B KMT2D WIZ CELSR2 RBM33 PLEKHA4 ZNF500 RELB EDC4 PTCH1 RASSF7 GRSF1 PRRC2B RAB11FIP3	4.05e-06	1470	88	20	int:TOP3B
Interaction	NCKAP1 interactions	TAOK2 PLEKHA4 ADNP2 SYN2 NYAP1 WIPF2 VIRMA SHANK3	5.04e-06	218	88	8	int:NCKAP1
Interaction	TLE3 interactions	SPTBN4 PRR12 KMT2D PYGO2 HOXC13 TCF20 SCAF8 ZNF207 TAF4 VIRMA	5.62e-06	376	88	10	int:TLE3
Interaction	CEBPA interactions	PRR12 ATXN2L TTF2 KMT2D WIZ TCF20 WIPF1 RBM33 CPSF6 BAG1 ZNF207 TAF4 EDC4 RFX5 CSTF2T PRRC2B DNM2 FOSL1	5.89e-06	1245	88	18	int:CEBPA
Interaction	JUN interactions	ATXN2L TCF20 WIPF1 BAG1 MEPCE TAF4 BCL3 EDC4 PPP1R13L VIRMA FOSL1	6.28e-06	470	88	11	int:JUN
Interaction	CSTF2T interactions	COL17A1 CPSF6 PLEKHA4 RFX5 VIRMA CSTF2T	6.64e-06	105	88	6	int:CSTF2T
Interaction	EYA4 interactions	KCTD12 PRR12 ATXN2L TROAP RBM33 CPSF6 CCDC120 PRRC2B	1.12e-05	243	88	8	int:EYA4
Interaction	NUP35 interactions	PRR12 KMT2D PYGO2 TCF20 RBM33 CPSF6 SCAF8 PLEKHA4 ZNF207 PRRC2B	1.60e-05	424	88	10	int:NUP35
Interaction	SOX7 interactions	PRR12 KMT2D WIZ TCF20 ADNP2	2.96e-05	82	88	5	int:SOX7
Interaction	FEV interactions	PRR12 KMT2D WIZ TCF20 TAF4 RFX5 PRRC2B	3.02e-05	203	88	7	int:FEV
Interaction	CBX4 interactions	ATXN2L WIZ CBX6 PCLO PLEKHA4 MEPCE VIRMA	3.22e-05	205	88	7	int:CBX4
Interaction	IRF4 interactions	PRR12 KMT2D PYGO2 TCF20 PRRC2B	3.53e-05	85	88	5	int:IRF4
Interaction	EWSR1 interactions	KCTD12 PRR12 WIZ TCF20 RBM33 CPSF6 PCLO PLEKHA4 MEPCE ZNF207 TAF4 RFX5 VIRMA CSTF2T	3.61e-05	906	88	14	int:EWSR1
Interaction	PCDHGB2 interactions	CBX6 PPP1R13L VIRMA DNM2	4.03e-05	44	88	4	int:PCDHGB2
Interaction	PLOD1 interactions	TAOK2 COL4A5 ATXN2L COL12A1 CPSF6 PLEKHA4 PRRC2B DNM2	4.16e-05	292	88	8	int:PLOD1
Interaction	PPP1R13L interactions	CBX6 PLEKHA4 PPP1R13L SHANK3 PRRC2B	4.17e-05	88	88	5	int:PPP1R13L
Interaction	HCFC1 interactions	KMT2D CPSF6 PLEKHA4 MED25 PHLPP1 TAF4 NYAP1 VIRMA	4.26e-05	293	88	8	int:HCFC1
Interaction	UBAP2L interactions	TAOK2 ATXN2L DMRT2 CPSF6 PLEKHA4 PHLPP1 VIRMA PRRC2B	4.80e-05	298	88	8	int:UBAP2L
Interaction	SP7 interactions	PRR12 KMT2D WIZ PYGO2 TCF20 RBM33 SCAF8 PRRC2B	5.52e-05	304	88	8	int:SP7
Interaction	ACTG1P20 interactions	PLEKHA4 VIRMA	5.64e-05	3	88	2	int:ACTG1P20
Interaction	ACAT1 interactions	TTF2 BAG1 PLEKHA4 MEPCE VIRMA GRSF1 SHANK3	7.04e-05	232	88	7	int:ACAT1
Interaction	ACAP1 interactions	ACAP1 MEPCE RAB11FIP3	7.41e-05	19	88	3	int:ACAP1
Interaction	SMG7 interactions	PRR12 KMT2D TCF20 RBM33 CPSF6 SCAF8 PLEKHA4 PRRC2B	7.73e-05	319	88	8	int:SMG7
Interaction	NUFIP2 interactions	KCTD12 ATXN2L CBX6 CPSF6 PLEKHA4 MEPCE PHLPP1 CSTF2T DNM2	8.61e-05	417	88	9	int:NUFIP2
Interaction	KLHL12 interactions	TAOK2 TBC1D10C CPSF6 PLEKHA4 MED25	9.27e-05	104	88	5	int:KLHL12
Interaction	BCR interactions	TAOK2 UNC119 CPSF6 PLEKHA4 EDC4 VIRMA SHANK3	9.65e-05	244	88	7	int:BCR
Interaction	SH3RF1 interactions	ACAP1 WIPF1 PRB3 VIRMA DNM2	1.11e-04	108	88	5	int:SH3RF1
Interaction	PDAP1 interactions	BAG1 PLEKHA4 PHLPP1 VIRMA SHANK3	1.11e-04	108	88	5	int:PDAP1
Interaction	PIK3C2G interactions	BAG1 VIRMA	1.12e-04	4	88	2	int:PIK3C2G
Interaction	SNRPEP2 interactions	PLEKHA4 MEPCE	1.12e-04	4	88	2	int:SNRPEP2
Interaction	CLTC interactions	TNK1 TROAP CPSF6 BAG1 PLEKHA4 MEPCE PHLPP1 EDC4 PTCH1 VIRMA DNM2	1.30e-04	655	88	11	int:CLTC
Interaction	KIF3B interactions	WIZ PLEKHA4 VIRMA SHANK3	1.37e-04	60	88	4	int:KIF3B
Interaction	THUMPD1 interactions	BAG1 PLEKHA4 MEPCE GRSF1	1.77e-04	64	88	4	int:THUMPD1
Interaction	PROB1 interactions	PHLPP1 PROB1	1.87e-04	5	88	2	int:PROB1
Interaction	GRB2 interactions	ACAP1 WIPF1 RBM33 OTUD5 CPSF6 PAK4 PLEKHA4 SIT1 WIPF2 SHANK3 CSTF2T DNM2	1.94e-04	806	88	12	int:GRB2
Interaction	EIF5A interactions	ATXN2L MAPK15 CPSF6 BAG1 PLEKHA4 MEPCE VIRMA	2.41e-04	283	88	7	int:EIF5A
Cytoband	22q13.3	TCF20 SHANK3	5.55e-05	6	89	2	22q13.3
Cytoband	12p13.2	PRB1 PRB3 PRB2	9.42e-05	45	89	3	12p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	SPTBN4 PRR12 PAK4 PLEKHA4 MED25 TPRX1 RELB BCL3 PPP1R13L SLC7A10	1.07e-04	1192	89	10	chr19q13
Cytoband	19q13.33	PRR12 PLEKHA4 TPRX1	1.18e-03	106	89	3	19q13.33
Cytoband	7q22.1	COL26A1 MEPCE NYAP1	1.41e-03	113	89	3	7q22.1
Cytoband	12q13.12	KMT2D TROAP	2.50e-03	38	89	2	12q13.12
GeneFamily	Proline rich proteins	PRB1 PRB3 PRB2	6.56e-07	6	59	3	972
GeneFamily	Collagens	COL4A5 COL12A1 COL17A1 COL26A1	1.51e-05	46	59	4	490
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN4 ACAP1 PLEKHA4 PHLPP1 DNM2	5.56e-04	206	59	5	682
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP8B BMP8A	5.65e-04	11	59	2	455
GeneFamily	RNA binding motif containing	RBM33 CPSF6 SCAF8 GRSF1 CSTF2T	6.47e-04	213	59	5	725
Coexpression	NABA_COLLAGENS	COL4A5 COL12A1 COL17A1 COL26A1	1.39e-05	43	89	4	MM17060
Coexpression	NABA_COLLAGENS	COL4A5 COL12A1 COL17A1 COL26A1	1.52e-05	44	89	4	M3005
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATXN2L CELSR2 CBX6 BCL3 RASSF7 FOSL1	2.01e-06	186	89	6	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATXN2L CELSR2 CBX6 BCL3 RASSF7 FOSL1	2.21e-06	189	89	6	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 ZC3H12D SIT1	2.57e-06	194	89	6	906fe1689906d1498acf6fd26a215c7e5a854a38
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 ZC3H12D SIT1	2.57e-06	194	89	6	af7428582b96a500f255c45efc02b6c10c4740d9
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 ZC3H12D SIT1	2.57e-06	194	89	6	4138f3e8aa214504fca03962a43250670ae45215
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACAP1 ADAM19 ZC3H12D SIT1	1.64e-05	158	89	5	b1b1e50ddd231dcd10cc8e6bb68b2a5e0bb1450a
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEMA6C TTLL11 GAL3ST3 NYAP1 SHANK3	2.14e-05	167	89	5	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEMA6C TTLL11 GAL3ST3 NYAP1 SHANK3	2.14e-05	167	89	5	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Treg\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBC1D10C ACAP1 CBX6 ZC3H12D SIT1	2.91e-05	178	89	5	e37142a84d9713ff1571ce9f976842bf5c17c86f
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNK1 COL17A1 TROAP BCL3 FOSL1	3.32e-05	183	89	5	bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCell	normal_Lung-T/NK_cells-Exhausted_CD8+_T\|normal_Lung / Location, Cell class and cell subclass	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	3.32e-05	183	89	5	a2901707d0f0900ff91c08c9152dad0b6c191cca
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	XYLT1 KMT2D MEPCE PHLPP1 RAB11FIP3	3.49e-05	185	89	5	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	(1)_T_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	TBC1D10C ACAP1 WIPF1 ZC3H12D SIT1	3.87e-05	189	89	5	fa6b85676b2b61483ae27720d0715dbfcbcfbdf9
ToppCell	wk_15-18-Hematologic_Lymphocytic-T_&_ILC-Treg\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TBC1D10C ACAP1 WIPF1 ZC3H12D SIT1	3.97e-05	190	89	5	fe6fecdf2123f3a4fb20e7535472d562b1a74fb4
ToppCell	Adult-Immune-T_lymphocyte-D175\|Adult / Lineage, Cell type, age group and donor	XYLT1 TBC1D10C ACAP1 ADAM19 ZC3H12D	4.07e-05	191	89	5	0b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCell	COVID-19-lung-CD4+_Treg\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XYLT1 TBC1D10C ACAP1 ADAM19 WIPF1	4.07e-05	191	89	5	5a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCell	COVID-19-lung-CD4+_Treg\|lung / Disease (COVID-19 only), tissue and cell type	XYLT1 TBC1D10C ACAP1 ADAM19 WIPF1	4.07e-05	191	89	5	73ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCell	NS-critical-d_07-13-Lymphoid-Treg\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TBC1D10C ACAP1 ADAM19 ZC3H12D SIT1	4.17e-05	192	89	5	cd34defac6565d34db507918e791b09c79f7d1f8
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 WIPF1 ZC3H12D SIT1	4.17e-05	192	89	5	985fff79e645f0670eee8a0c8db08b5f7822e27a
ToppCell	COVID-19_Moderate-Plasmablast\|COVID-19_Moderate / disease group, cell group and cell class	ENAM BMP8B ADAM19 TROAP WFS1	4.17e-05	192	89	5	25c6c7a244190f82c7feab874bdec12490b7de4d
ToppCell	COVID-19_Severe-Plasmablast\|World / disease group, cell group and cell class	ENAM BMP8B ADAM19 TROAP WFS1	4.17e-05	192	89	5	a333053fe2bd206c32790916bfc5fce904ab7f57
ToppCell	NS-control-d_0-4-Lymphoid-Treg\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.17e-05	192	89	5	ef252dd9df161f665f53c047c0514381f80d6683
ToppCell	NS-moderate-d_07-13-Lymphoid\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.17e-05	192	89	5	bd4059bfc2159f5ed8bbb2a5408b56117ca6f8e1
ToppCell	control-Lymphoid-Treg\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.17e-05	192	89	5	9067e90b7c2d734100d6e5026d753113bf9428a3
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 CELSR2 PCLO SYN2 NYAP1	4.27e-05	193	89	5	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|367C / Donor, Lineage, Cell class and subclass (all cells)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.27e-05	193	89	5	8f8d2006fb40a207c743cfd2e9a9f47c2bac1eea
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SPTBN4 TTLL11 GAL3ST3 SYN2 NYAP1	4.27e-05	193	89	5	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.27e-05	193	89	5	7022b3ce6220d6d1722a4e2947630a8da002cdce
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.27e-05	193	89	5	3083305b7ae09a37d7f45b915d49b2b396276822
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.27e-05	193	89	5	1218e74ee5e00d230222b10acc50cb96201016b4
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 CELSR2 PCLO SYN2 NYAP1	4.27e-05	193	89	5	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 CELSR2 PCLO SYN2 NYAP1	4.27e-05	193	89	5	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD4+_Th\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.27e-05	193	89	5	ebb22400b683a7d135448822ad2a32cb1059e104
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.38e-05	194	89	5	1bb5ac162f547de9dd91680df247b49a00920062
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SPTBN4 PCLO TTLL11 SYN2 NYAP1	4.38e-05	194	89	5	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.38e-05	194	89	5	2e614d86c366a022929ae307f170db8b142c386a
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SPTBN4 PRB1 PRB3 PRB2 C6orf15	4.38e-05	194	89	5	e90f6717e3421f8978d1fc1b2f30dcf69f6fcce7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	XYLT1 TBC1D10C ACAP1 ADAM19 SIT1	4.38e-05	194	89	5	633fe72cc8a489abde12428e326478409ca03263
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	XYLT1 TBC1D10C ACAP1 ADAM19 SIT1	4.38e-05	194	89	5	87a86df0b542f287b0b20f4a4b1a37002271671d
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.38e-05	194	89	5	7937f2d1113bd85fee0df95fab74b0e022cdebce
ToppCell	COVID-19-lung-CD4+_T_cells_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	XYLT1 TBC1D10C ACAP1 ADAM19 WIPF1	4.38e-05	194	89	5	2a144a1c2d537c8a59aa419206ddd96c23f0aeab
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-B_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.49e-05	195	89	5	daacbccf2a6a5ce1f0e3d1743a475076b4411c56
ToppCell	cellseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.49e-05	195	89	5	120412817b5ef3293238a65903234b6d4ea8dd5c
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-T_reg\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ACAP1 WIPF1 TROAP ZC3H12D SIT1	4.60e-05	196	89	5	6362fb0b5dc923f19a76b605d7289a16f89220e3
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.60e-05	196	89	5	c7363794fb731848e4343b3a4e4f800f9c81999a
ToppCell	control-Lymphoid\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.60e-05	196	89	5	8ed172bb3a95f09722476f0880ae246561777d98
ToppCell	NS-control-d_0-4-Lymphoid\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.71e-05	197	89	5	bd3f2d68eb108fe31e217c9124183920e7c82582
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.71e-05	197	89	5	927bf36bad3bcb7346c13b660777c1c0de7dc322
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 SNPH WIPF1 TTLL11	4.71e-05	197	89	5	52246d1354c4e2b13d48c878643edf843d2b50d2
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.71e-05	197	89	5	3e09158507df08c08e08613ce23617206280c911
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.71e-05	197	89	5	dfec2afd1cbe218c9234ce7d4b5a5839b268398d
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.83e-05	198	89	5	f486747f2c96b403bdeee0dfe0cc2679ffeefa33
ToppCell	Biopsy_IPF-Immune-B_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.83e-05	198	89	5	6a519337a4932a7b685fe7defd3de24fa2016b7d
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-T-T_CD4\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 ZC3H12D SIT1	4.83e-05	198	89	5	12cd44bc02c7577fbcf230957a1fecc1e5bfde37
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TBC1D10C ACAP1 WIPF1 PROB1 SIT1	4.83e-05	198	89	5	6afb43c7c415c5bb7c577eab56653ede2b349524
ToppCell	distal-1-Hematologic-Myeloid_Dendritic_Type_2\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	XYLT1 ACAP1 ADAM19 CBX6 PROB1	4.83e-05	198	89	5	5b27949ac3fc7eb34949f9f360d57e6ae82a2368
ToppCell	mild-Plasmablast\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ENAM BMP8B ADAM19 TROAP WFS1	4.83e-05	198	89	5	b14b9e67815f93fac7bd8e5e6f1aa100951b4ac1
ToppCell	Severe-CD4+_T_Exhausted\|Severe / Disease group and Cell class	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	dc6b0291714e2b9501c0796a63678bfb9d1b1052
ToppCell	proximal-3-Hematologic-CD4+_Memory/Effector_T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	8d9dd152fd969b6cef3e161624ac41722a1609e8
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	5a29db2610ba06a2248325a16cad755d20debf2c
ToppCell	distal-Hematologic-CD4+_Memory/Effector_T-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	1d073b5bc664d1449ede76eea6a08146a772fe91
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 WIPF1 ZC3H12D	4.94e-05	199	89	5	6150b272313d3fbf5ddcb3a8d51862d368220fe2
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 WIPF1 ZC3H12D SIT1	4.94e-05	199	89	5	6272c65f9dd0ae667856416bdb3fb27cab39d772
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	01ae5ce8e0a1d3bd1cc975b16f53c13bbc13189d
ToppCell	Bronchus_Control_(B.)-Immune-TX-T_cells\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	TBC1D10C ACAP1 WIPF1 ZC3H12D SIT1	4.94e-05	199	89	5	cb4cd42e608126227cbbf2342486550bcd4d0fc9
ToppCell	proximal-Hematologic-CD4+_Memory/Effector_T-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	6b97202f1f68ce480b489ee1eae40e42c1d6281c
ToppCell	distal-Hematologic-CD4+_Memory/Effector_T\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	96bbe51dd099a879fa5b2e2ac68ca1c6925b5997
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	5fc9bd5740e2e4d657c8c3dd26567db9a6da5af8
ToppCell	proximal-Hematologic-CD4+_Memory/Effector_T\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	bebac41cc51dcf52997cbb8b299761ec688d2c02
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	XYLT1 COL4A5 WIZ ADNP2 PHLPP1	4.94e-05	199	89	5	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	4.94e-05	199	89	5	630acf00cc0ad50c9b783f4f71c42e11e5d68f8c
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	SPTBN4 SNPH PCLO SYN2 NYAP1	5.06e-05	200	89	5	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 WIPF1 ZC3H12D	5.06e-05	200	89	5	d8459e45a8396a9ee063666a1928c649162c5727
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	XYLT1 ACAP1 ADAM19 WIPF1 ZC3H12D	5.06e-05	200	89	5	cded40d5069a6fdbd90ac9a2a0bbef11727b28d5
ToppCell	Biopsy_IPF-Immune-T_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	5.06e-05	200	89	5	368c7334d211054f1e914a1be4027aa75e2df66c
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SPTBN4 PRB1 PRB3 PRB2 RAB11FIP3	5.06e-05	200	89	5	61bae10c8b12196d9cee766897971b81cb897191
ToppCell	distal-3-Hematologic-CD4+_Memory/Effector_T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	5.06e-05	200	89	5	c60d18e66781399426239bd27bc1539bcccaa761
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D10C ACAP1 ADAM19 WIPF1 SIT1	5.06e-05	200	89	5	283c55076133de5ce195ccad997ffddc56ed32a2
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBC1D10C TTF2 ACAP1 ZC3H12D	1.27e-04	128	89	4	c2045f052cc713e52312eb015825711576fcb6c5
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|367C / Donor, Lineage, Cell class and subclass (all cells)	TBC1D10C ACAP1 ZC3H12D SIT1	2.04e-04	145	89	4	29422c908d58081e6a748e362a7ac41bf001444c
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-regulatory_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TAOK2 TTF2 PYGO2 PRRC2B	2.10e-04	146	89	4	7748277cf2f12e2930d4f5a22247ab9bc266a954
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CAMKK2 COL17A1 WFS1 C6orf15	2.21e-04	148	89	4	223d6a640f3c34e73646a615593b9c0b4a4cbd6f
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal-Igfbp4_(Entorhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HJV DMRT2 ZC3H12D	2.36e-04	60	89	3	604f050cafb1c2378a6957831833d47ff555c1fd
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal-Igfbp4_(Entorhinal_cortex)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HJV DMRT2 ZC3H12D	2.36e-04	60	89	3	831efcadd99ad04d37cd763ecf8aaa439b09046d
ToppCell	Adult-Immune-enucleated_erythrocyte-D175\|Adult / Lineage, Cell type, age group and donor	CELSR2 COL26A1 GRIN2C EDC4	2.45e-04	152	89	4	530d5427d8617dcb223d807b73abee0ef89285f3
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	SPTBN4 TBC1D10C DMRT2 SIT1	2.51e-04	153	89	4	ce7a23c687e9e7d83d244046de19c854caded09b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TROAP RELB SHANK3 FOSL1	2.63e-04	155	89	4	59035d792c26d870a8b097939e97fa47859ba68c
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-5\|TCGA-Stomach / Sample_Type by Project: Shred V9	UNC119 HOXC13 COL26A1 SLC7A10	2.90e-04	159	89	4	c40fe552da3abdb1df87e9e1647468dc038bec0a
ToppCell	COVID-CD4-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	KIF13B KMT2D ADAM19 VIRMA	2.90e-04	159	89	4	037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBC1D10C UNC119 KIF13B ACAP1	2.97e-04	160	89	4	b2d8940ea8c068273b7da1589d3d6ae5110d8209
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBC1D10C UNC119 KIF13B ACAP1	2.97e-04	160	89	4	9caab1bb63c7e66c44783852ee75b16bb40fa594
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACAP1 ZC3H12D SIT1	2.97e-04	160	89	4	9e238e7cb31070a5b9da73b4bfddde54b969b0fd
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACAP1 ZC3H12D SIT1	2.97e-04	160	89	4	3a5a7984d9ffcb0fbada02b95ffd7aca091acf30
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBC1D10C UNC119 KIF13B ACAP1	2.97e-04	160	89	4	229841be7b984a00a301cd5d88c11226a90d8a88
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D10C ACAP1 ZC3H12D SIT1	2.97e-04	160	89	4	32a105b99fc565c944672f518d6947dcf9ea8832
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBC1D10C UNC119 KIF13B ACAP1	2.97e-04	160	89	4	99c9ae2041445539fada842e1af01368669bfca0
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNPH COL17A1 PAK4 CCDC120	3.04e-04	161	89	4	ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNPH COL17A1 PAK4 CCDC120	3.04e-04	161	89	4	0089d7bb305c592392791862a3341fc92af8f3e2
ToppCell	Frontal_cortex\|World / BrainAtlas - Mouse McCarroll V32	ERFE CAMKK2 COL12A1 DMRT2	3.26e-04	164	89	4	e09291711abf8680e78170328313719092b0142f
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TAOK2 XYLT1 MAPK15 USP21	3.26e-04	164	89	4	d2218d50e0e2d19f919dcb460b3840687c082810
Drug	Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	TAOK2 CAMKK2 SNPH COL17A1 WIZ GRIN2C PTCH1 DNM2	1.02e-06	196	89	8	1481_UP
Drug	Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A	TAOK2 UNC119 ADAM19 C1orf159 RASSF7 DNM2 USP21 FOSL1	1.14e-06	199	89	8	3574_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A	CAMKK2 CBX6 SCAF8 MEPCE RASSF7 USP21 FOSL1	7.37e-06	182	89	7	1891_DN
Drug	alanine	ATXN2L TTF2 TCF20 PRB1 MRGPRE C6orf15 SLC7A10 GRSF1	1.06e-05	269	89	8	CID000000602
Drug	Praziquantel [55268-74-1]; Down 200; 12.8uM; PC3; HT_HG-U133A	TAOK2 KIF13B CELSR2 ZNF500 C1orf159 PTCH1 PRRC2B	1.23e-05	197	89	7	5874_DN
Drug	haloperidol; Down 200; 10uM; PC3; HT_HG-U133A	TNK1 SNPH WIZ CPSF6 ZNF500 BCL3 EDC4	1.32e-05	199	89	7	1203_DN
Drug	Alsterpaullone; Down 200; 10uM; PC3; HT_HG-U133A	TROAP SCAF8 MEPCE ADNP2 CSTF2T USP21	8.56e-05	184	89	6	7056_DN
Drug	SnBr4	BCL3 PTCH1	9.02e-05	4	89	2	CID000024616
Drug	15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A	TAOK2 HOXC13 TROAP PHLPP1 BCL3 PPP1R13L	9.36e-05	187	89	6	6948_DN
Drug	17-DMAG; Down 200; 0.1uM; PC3; HT_HG-U133A	TTF2 SNPH TROAP BCL3 PPP1R13L RAB11FIP3	9.63e-05	188	89	6	1213_DN
Drug	Alsterpaullone; Down 200; 10uM; PC3; HT_HG-U133A	TROAP SCAF8 MEPCE ADNP2 TAF4 CSTF2T	9.63e-05	188	89	6	7078_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	UNC119 WIZ WIPF1 RELB CSTF2T RAB11FIP3	1.11e-04	193	89	6	3973_DN
Drug	Simvastatin [79902-63-9]; Down 200; 9.6uM; PC3; HT_HG-U133A	WIZ WIPF1 MED25 RELB BCL3 RAB11FIP3	1.14e-04	194	89	6	4244_DN
Drug	2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A	TNK1 WIZ ZNF500 MEPCE PRRC2B USP21	1.14e-04	194	89	6	1209_DN
Drug	Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; PC3; HG-U133A	KCTD12 SNPH WIZ MED25 RASSF7 PRRC2B	1.18e-04	195	89	6	1911_UP
Drug	Miconazole [22916-47-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A	KIF13B ACAP1 SNPH WIPF1 RELB BMP8A	1.18e-04	195	89	6	4960_UP
Drug	Cefadroxil [50370-12-2]; Up 200; 11uM; HL60; HT_HG-U133A	ATXN2L WIZ PAK4 ZNF500 PLPPR3 WIPF2	1.21e-04	196	89	6	1323_UP
Drug	CP-645525-01 [287190-82-3]; Down 200; 10uM; PC3; HT_HG-U133A	UNC119 HOXC13 CELSR2 CPSF6 MED25 CSTF2T	1.21e-04	196	89	6	7527_DN
Drug	Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; PC3; HT_HG-U133A	TAOK2 TNK1 SNPH WIZ MED25 C1orf159	1.21e-04	196	89	6	5830_DN
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	UNC119 KIF13B CELSR2 PTCH1 FOSL1 RAB11FIP3	1.24e-04	197	89	6	1635_UP
Drug	Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; PC3; HT_HG-U133A	ACAP1 CELSR2 RELB BMP8A SIT1 RAB11FIP3	1.24e-04	197	89	6	5881_UP
Drug	Boldine [476-70-0]; Down 200; 12.2uM; HL60; HT_HG-U133A	UNC119 TNK1 ATXN2L PAK4 DNM2 FOSL1	1.24e-04	197	89	6	2148_DN
Drug	Aminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A	TAOK2 KIF13B WIZ PCLO PAK4 DNM2	1.24e-04	197	89	6	3122_DN
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A	ATXN2L CAMKK2 SNPH SYN2 BMP8A SIT1	1.24e-04	197	89	6	5641_UP
Drug	Diperodon hydrochloride [537-12-2]; Down 200; 9.2uM; PC3; HT_HG-U133A	TAOK2 UNC119 ZNF500 MED25 RASSF7 RAB11FIP3	1.28e-04	198	89	6	4498_DN
Drug	Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; MCF7; HT_HG-U133A	TAOK2 UNC119 TNK1 WIZ PPP1R13L CSTF2T	1.28e-04	198	89	6	7199_DN
Drug	Apomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; HL60; HG-U133A	ZNF500 SYN2 PLPPR3 C1orf159 RFX5 FOSL1	1.28e-04	198	89	6	2005_UP
Drug	Guanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A	TAOK2 ATXN2L WIPF1 MED25 PHLPP1 BCL3	1.28e-04	198	89	6	2634_UP
Drug	Lisinopril [83915-83-7]; Down 200; 9uM; MCF7; HT_HG-U133A	TAOK2 ATXN2L WIZ RASSF7 CSTF2T FOSL1	1.32e-04	199	89	6	7403_DN
Drug	(R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; MCF7; HT_HG-U133A	TAOK2 KIF13B WIPF1 C1orf159 CSTF2T FOSL1	1.32e-04	199	89	6	2855_DN
Drug	Torsemide [56211-40-6]; Down 200; 11.4uM; PC3; HT_HG-U133A	KIF13B SNPH WIPF1 ZNF500 MED25 RELB	1.32e-04	199	89	6	5057_DN
Drug	DAPH; Up 200; 10uM; PC3; HG-U133A	ATXN2L WIZ WIPF1 CELSR2 PRRC2B USP21	1.32e-04	199	89	6	578_UP
Drug	Proxyphylline [603-00-9]; Up 200; 16.8uM; PC3; HT_HG-U133A	TAOK2 ATXN2L WIPF1 CELSR2 MED25 RAB11FIP3	1.32e-04	199	89	6	7290_UP
Drug	Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A	TAOK2 SNPH MED25 CSTF2T PRRC2B RAB11FIP3	1.32e-04	199	89	6	2057_DN
Disease	Phelan-McDermid syndrome (implicated_via_orthology)	TCF20 SHANK3	8.59e-06	2	87	2	DOID:0080354 (implicated_via_orthology)
Disease	diabetes mellitus (implicated_via_orthology)	BMP8B WFS1 BMP8A	6.13e-05	26	87	3	DOID:9351 (implicated_via_orthology)
Disease	glucagon-like peptide-1 measurement	ENAM COL12A1	3.81e-04	10	87	2	EFO_0008465
Disease	Amelogenesis Imperfecta	ENAM COL17A1	5.56e-04	12	87	2	C0002452
Disease	collagen disease (implicated_via_orthology)	COL4A5 DNM2	5.56e-04	12	87	2	DOID:854 (implicated_via_orthology)
Disease	Schizoaffective disorder-bipolar type	PCLO PTCH1	1.00e-03	16	87	2	EFO_0009965
Disease	serum alanine aminotransferase measurement	XYLT1 ATXN2L COL12A1 CELSR2 PCLO SYN2 USP35 PTCH1 USP21	1.05e-03	869	87	9	EFO_0004735
Disease	autism spectrum disorder (implicated_via_orthology)	TAOK2 TCF20 SYN2 SHANK3	1.08e-03	152	87	4	DOID:0060041 (implicated_via_orthology)
Disease	Schizophrenia	SYN2 SHANK3	1.28e-03	18	87	2	cv:C0036341
Disease	neoplasm of mature B-cells	C6orf15 PHLPP1	1.58e-03	20	87	2	EFO_0000096
Disease	asthma	ADAM19 SCAF8 ZC3H12D GAL3ST3 BCL3 PTCH1 SLC7A10 FOSL1	1.69e-03	751	87	8	MONDO_0004979
Disease	intermediate density lipoprotein measurement	CELSR2 RELB BCL3	2.19e-03	87	87	3	EFO_0008595
Disease	breast cancer (is_marker_for)	KMT2D MAPK15 BAG1 RELB	2.22e-03	185	87	4	DOID:1612 (is_marker_for)
Disease	lung squamous cell carcinoma (is_implicated_in)	KMT2D PTCH1	2.27e-03	24	87	2	DOID:3907 (is_implicated_in)
Disease	necrotizing enterocolitis	TCF20 SYN2	2.88e-03	27	87	2	EFO_0003928
Disease	C-reactive protein measurement	SEMA6C ATXN2L CAMKK2 ADAM19 CELSR2 CBX6 RELB TAF4 BCL3 FOSL1	2.89e-03	1206	87	10	EFO_0004458

Protein segments in the cluster

Peptide	Gene	Start	Entry
EVLNLQGPPGPPGPR	COL17A1	851	Q9UMD9
RPDPQGGSPGLRPPI	CBX6	136	O95503
QQPSGRGNPRPAPSP	SLC7A10	6	Q9NS82
PLRPPGAGPQQSRPL	ADAM19	881	Q9H013
RQSEPPAQRGPPPSG	BAG1	31	Q99933
GGRGRPRGQPPVPPK	ACAP1	531	Q15027
GGPPPRPPPRQSLQE	CELSR2	2876	Q9HCU4
PPPTQQAVARRPPGG	ATXN2L	16	Q8WWM7
PVGPINRPVGPGVLP	ADNP2	406	Q6IQ32
PPRPDRGPPGTQGPL	RASSF7	306	Q02833
RGPPGTQGPLPPARE	RASSF7	311	Q02833
RPVRPALQPPGPVGI	RBM33	526	Q96EV2
PGPGRAPPGGLTQPR	RFX5	396	P48382
RQGPTAPPPPRGPAL	HJV	121	Q6ZVN8
GPSAPPPRSGPRGQL	RAB11FIP3	86	O75154
LGRLVSPAPGPGPQP	RELB	111	Q01201
PRPRPGPELGPQLGL	EDC4	781	Q6P2E9
LQTGPVPPGRLAGPP	GRSF1	66	Q12849
GTELGPPAPPRPRNG	MEPCE	121	Q7L2J0
TPVQGPRPRPQSSPG	MAPK15	381	Q8TD08
AGPQRRPVLPSVGPP	CCDC120	571	Q96HB5
SGRPPDPGRPAQPGL	PCLO	96	Q9Y6V0
RREPPPGNELPRGPG	ERFE	41	Q4G0M1
SGGPRGPVPQPGLQP	MED25	721	Q71SY5
GPQRPPPRGFPGLIL	MRGPRE	206	Q86SM8
IPSRPVRIPPGIPPG	DNM2	831	P50570
PFGPSPLQRPGQGLP	PYGO2	221	Q9BRQ0
GINNPFPPGVLRPPG	C6orf15	291	Q6UXA7
PPPRPIRVLPRGPQG	GAL3ST3	416	Q96A11
GQVLPPPLAGPPNRG	CPSF6	256	Q16630
GQPEQRGGPQPRPPL	DMRT2	76	Q9Y5R5
RGGPQPRPPLAPQAS	DMRT2	81	Q9Y5R5
PRGLPGPPGPQGESR	COL12A1	2996	Q99715
GPPGPPGQISEQKRP	COL4A5	236	P29400
GGPGLRPPPGCPQRR	BMP8A	21	Q7Z5Y6
PVLGRPPAPLGAPQG	HOXC13	76	P31276
PPPRGTRPAPGGCIQ	CAMKK2	211	Q96RR4
RAPIPRGPVTPGGLP	CSTF2T	311	Q9H0L4
IPQRLPPPGYGRPPI	ENAM	176	Q9NRM1
GGPGLRPPPGCPQRR	BMP8B	21	P34820
GVLRGPGRPVPPSPA	BCL3	436	P20749
PLPGSPGDPPTRQGQ	C1orf159	241	Q96HA4
IRPGLIPQAPGPRFP	SCAF8	926	Q9UPN6
GPRFPLIQPGIPPQR	SCAF8	936	Q9UPN6
APSPRPGPGPLRQQG	PPP1R13L	156	Q8WUF5
VRRLGAPQQPGPGPP	KCTD12	126	Q96CX2
APQQPGPGPPPSRRG	KCTD12	131	Q96CX2
VPRQRRPTGPAGPPG	COL26A1	191	Q96A83
GRPQGPPQQGGHPRP	PRH1;	106	P02810
PPQQGGHPRPPRGRP	PRH1;	111	P02810
GHPRPPRGRPQGPPQ	PRH1;	116	P02810
AGQPQGPPRPPQGGR	PRB2	396	P02812
PQPRPGVIRALGPPP	FOSL1	76	P15407
VVGARPRASPPPQGP	OTUD5	56	Q96G74
PAVPGPPGPRSPQRE	PAK4	281	O96013
LPPGPTPAQQPGRGL	FAM174A	56	Q8TBP5
PPGPSPRGGNLPLQR	NYAP1	181	Q6ZVC0
PPGPQQLVSPGRERP	KIF13B	1621	Q9NQT8
GPQRPGPPSPRRPLV	TAF4	101	O00268
QPPGKVLPPRRLPPG	SYN2	466	Q92777
QPRSPARPQPGEGPG	PLEKHA4	161	Q9H4M7
VHPPPVPGPGRNPRG	PTCH1	1381	Q13635
RAGQRPPGLPLPIPG	TAOK2	746	Q9UL54
RTQSRPGGPPNPPGP	WIZ	1091	O95785
RPLQSPPATGRPPGV	PRR12	566	Q9ULL5
PEPITRGPTPQRPGA	SNPH	376	O15079
RGPTPQRPGANPNPG	SNPH	381	O15079
GPGSGPRPPQPQLRT	PROB1	91	E7EW31
QPQRTPPPPGKPEGR	PRB3	46	Q04118
QGPPRPPQGGRPSRP	PRB1	376	P04280
VPSGGRPPHRGPPQE	TTLL11	756	Q8NHH1
VGGGEQPPPAPAPRR	XYLT1	51	Q86Y38
IGPIPSPAQIPGPGR	TPRX1	266	Q8N7U7
PILANGPVPSPPRRG	USP21	326	Q9UK80
GPGPRPGPLQRKQPI	UNC119	46	Q13432
PVREGRGIPPPPQTA	SHANK3	806	Q9BYB0
PGLGPRVILPPRAGP	PLPPR3	476	Q6T4P5
SAPGPPPRPQVRLAG	TBC1D10C	356	Q8IV04
LPPPTSAQGPGRVGP	USP35	626	Q9P2H5
RPSPRGQNVGPGPPA	TROAP	96	Q12815
VGAPRRIPPPGSQPP	PRRC2B	2106	Q5JSZ5
PRVLVRPPPPGCPGQ	SEMA6C	746	Q9H3T2
PQPRELPPGRLPNGL	SPTBN4	2346	Q9H254
RGSPPVPGGPRQPSP	WIPF1	201	O43516
TGTPQPPQRRPSGPV	TCF20	101	Q9UGU0
PLPRPPPRERQGPGD	nan	161	Q6ZRN7
GDLPPPPGLQLQPRG	ZC3H12D	401	A2A288
LPRPGQAPIGNPPVG	ZNF207	386	O43670
ARAVPQGPPGLPPRP	TNK1	526	Q13470
APTGVPGQPRRPGHP	PHLPP1	386	O60346
PGQPRRPGHPAQPLP	PHLPP1	391	O60346
PTPGQRLHPGREGPP	WIPF2	211	Q8TF74
RGAAPPPPPPVIRNG	WIPF2	321	Q8TF74
NGSPPRPQPRGPRTP	VIRMA	171	Q69YN4
QLRPPQGRIPGPGTP	SIT1	131	Q9Y3P8
PGHPLPGQRPAPVRG	ZNF500	286	O60304
LVRPDQPRGGPPPGR	ZNF500	301	O60304
PPQPLPRRGTQPVGS	TTF2	491	Q9UNY4
PRAPGPQAGPGPGVR	WFS1	41	O76024
GGTPFPGQGPPQRPR	KMT2D	2891	O14686
ELGAGPRPQGPPRLP	KMT2D	4276	O14686
VRRAPQPPGRPPTPG	GRIN2C	971	Q14957