Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhepoxilin-epoxide hydrolase activity

ALOX12 ALOX15

8.01e-062572GO:0047977
GeneOntologyMolecularFunctionhepoxilin A3 synthase activity

ALOXE3 ALOX15

8.01e-062572GO:0051120
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RASGRP4 KIAA1755 ARHGAP9 PLEKHG2 AGAP7P C9orf72 AGAP4 AGAP6 RGS12

1.24e-05507579GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RASGRP4 KIAA1755 ARHGAP9 PLEKHG2 AGAP7P C9orf72 AGAP4 AGAP6 RGS12

1.24e-05507579GO:0030695
GeneOntologyMolecularFunctionlinoleate 13S-lipoxygenase activity

ALOX12 ALOX15

2.40e-053572GO:0016165
GeneOntologyMolecularFunctionarachidonate 15-lipoxygenase activity

ALOX12 ALOX15

2.40e-053572GO:0050473
GeneOntologyMolecularFunctionarachidonate 12(S)-lipoxygenase activity

ALOX12 ALOX15

4.79e-054572GO:0004052
GeneOntologyMolecularFunctionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

ALOXE3 ALOX12 ALOX15

4.85e-0525573GO:0016702
GeneOntologyMolecularFunctionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen

ALOXE3 ALOX12 ALOX15

5.47e-0526573GO:0016701
GeneOntologyMolecularFunctionepoxide hydrolase activity

ALOX12 ALOX15

4.33e-0411572GO:0004301
GeneOntologyMolecularFunctionhydrolase activity, acting on ether bonds

ALOX12 ALOX15

6.12e-0413572GO:0016801
GeneOntologyMolecularFunctionether hydrolase activity

ALOX12 ALOX15

6.12e-0413572GO:0016803
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP9 AGAP7P AGAP4 AGAP6 RGS12

1.19e-03279575GO:0005096
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOR1 NCOA1

1.95e-0323572GO:0046965
GeneOntologyMolecularFunctionenzyme regulator activity

NCOR1 RASGRP4 FRY KIAA1755 ARHGAP9 PLEKHG2 AGAP7P C9orf72 AGAP4 AGAP6 RGS12

1.98e-0314185711GO:0030234
GeneOntologyMolecularFunctiondioxygenase activity

ALOXE3 ALOX12 ALOX15

2.77e-0398573GO:0051213
GeneOntologyMolecularFunctionpoly(A) binding

ELAVL4 PABPC1L

3.09e-0329572GO:0008143
GeneOntologyBiologicalProcesshepoxilin metabolic process

ALOXE3 ALOX12 ALOX15

9.95e-078553GO:0051121
GeneOntologyBiologicalProcesshepoxilin biosynthetic process

ALOXE3 ALOX12 ALOX15

9.95e-078553GO:0051122
GeneOntologyBiologicalProcesslipoxygenase pathway

ALOXE3 ALOX12 ALOX15

2.92e-0611553GO:0019372
GeneOntologyBiologicalProcesslipoxin A4 biosynthetic process

ALOX12 ALOX15

2.09e-053552GO:2001303
GeneOntologyBiologicalProcesslinoleic acid metabolic process

ALOXE3 ALOX12 ALOX15

3.06e-0523553GO:0043651
GeneOntologyBiologicalProcesscellular response to Thyroglobulin triiodothyronine

NCOR1 NCOA1

4.17e-054552GO:1904017
GeneOntologyBiologicalProcesslipoxin A4 metabolic process

ALOX12 ALOX15

4.17e-054552GO:2001302
GeneOntologyBiologicalProcesslipoxin biosynthetic process

ALOX12 ALOX15

4.17e-054552GO:2001301
GeneOntologyBiologicalProcessperoxisome proliferator activated receptor signaling pathway

NCOA1 ALOXE3 ALOX15

5.61e-0528553GO:0035357
GeneOntologyBiologicalProcesslong-chain fatty acid biosynthetic process

ALOXE3 ALOX12 ALOX15

6.24e-0529553GO:0042759
GeneOntologyBiologicalProcesslipoxin metabolic process

ALOX12 ALOX15

6.95e-055552GO:2001300
GeneOntologyBiologicalProcessresponse to Thyroglobulin triiodothyronine

NCOR1 NCOA1

1.04e-046552GO:1904016
GeneOntologyBiologicalProcessestablishment of skin barrier

NCOR1 ALOXE3 ALOX12

1.78e-0441553GO:0061436
GeneOntologyBiologicalProcessregulation of thyroid hormone receptor signaling pathway

NCOR1 NCOA1

1.93e-048552GO:0002155
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NCOR1 NCOA1 ALOXE3 CNOT2 ALOX15

2.00e-04202555GO:0141193
GeneOntologyBiologicalProcessthyroid hormone receptor signaling pathway

NCOR1 NCOA1

2.48e-049552GO:0002154
GeneOntologyBiologicalProcesslipid modification

SYNJ1 RNF213 ALOXE3 ALOX12 ALOX15

2.62e-04214555GO:0030258
GeneOntologyCellularComponentsperm cytoplasmic droplet

ROPN1B ROPN1

7.53e-055582GO:0097598
DomainLipOase_mml

ALOXE3 ALOX12 ALOX15

5.07e-076563IPR001885
DomainLIPOXYGENASE_1

ALOXE3 ALOX12 ALOX15

5.07e-076563PS00711
DomainLipOase_C

ALOXE3 ALOX12 ALOX15

5.07e-076563IPR013819
DomainLipoxygenase

ALOXE3 ALOX12 ALOX15

5.07e-076563PF00305
DomainLIPOXYGENASE_3

ALOXE3 ALOX12 ALOX15

5.07e-076563PS51393
DomainLIPOXYGENASE_2

ALOXE3 ALOX12 ALOX15

5.07e-076563PS00081
DomainLipOase

ALOXE3 ALOX12 ALOX15

5.07e-076563IPR000907
DomainLipOase_Fe_BS

ALOXE3 ALOX12 ALOX15

5.07e-076563IPR020833
DomainLipOase_CS

ALOXE3 ALOX12 ALOX15

5.07e-076563IPR020834
DomainLH2

ALOXE3 ALOX12 ALOX15

2.02e-0518563SM00308
DomainPLAT

ALOXE3 ALOX12 ALOX15

3.27e-0521563PS50095
Domain-

ALOXE3 ALOX12 ALOX15

3.27e-05215632.60.60.20
DomainPLAT

ALOXE3 ALOX12 ALOX15

3.27e-0521563PF01477
DomainPLAT/LH2_dom

ALOXE3 ALOX12 ALOX15

3.27e-0521563IPR001024
DomainArfGap

AGAP7P AGAP4 AGAP6

8.83e-0529563SM00105
DomainArfGap

AGAP7P AGAP4 AGAP6

8.83e-0529563PF01412
DomainARFGAP

AGAP7P AGAP4 AGAP6

8.83e-0529563PS50115
DomainArfGAP

AGAP7P AGAP4 AGAP6

8.83e-0529563IPR001164
DomainAnk_3

ANK1 TNKS

3.91e-0410562PF13606
DomaincAMP_dep_PK_reg_su_I/II_a/b

ROPN1B ROPN1

9.04e-0415562IPR003117
DomainANK

ANK1 TNKS AGAP7P AGAP4 AGAP6

9.20e-04251565SM00248
DomainANK_REPEAT

ANK1 TNKS AGAP7P AGAP4 AGAP6

9.54e-04253565PS50088
DomainAnkyrin_rpt-contain_dom

ANK1 TNKS AGAP7P AGAP4 AGAP6

9.70e-04254565IPR020683
DomainANK_REP_REGION

ANK1 TNKS AGAP7P AGAP4 AGAP6

9.70e-04254565PS50297
DomainAnkyrin_rpt

ANK1 TNKS AGAP7P AGAP4 AGAP6

1.11e-03262565IPR002110
DomainPH

ARHGAP9 PLEKHG2 AGAP7P AGAP4 AGAP6

1.45e-03278565SM00233
DomainPH_DOMAIN

ARHGAP9 PLEKHG2 AGAP7P AGAP4 AGAP6

1.47e-03279565PS50003
DomainPH_domain

ARHGAP9 PLEKHG2 AGAP7P AGAP4 AGAP6

1.50e-03280565IPR001849
DomainPH_dom-like

ARHGAP9 PLEKHG2 AGAP7P AGAP4 AGAP6 RGS12

1.68e-03426566IPR011993
DomaintRNA-bd_arm

PPFIA2 RPRD2

2.34e-0324562IPR010978
DomainSAM

EPHB2 PPFIA2 TNKS

2.34e-0388563SM00454
DomainSAM_DOMAIN

EPHB2 PPFIA2 TNKS

2.91e-0395563PS50105
DomainSAM

EPHB2 PPFIA2 TNKS

3.08e-0397563IPR001660
DomainAnk_2

ANK1 TNKS AGAP4 AGAP6

3.93e-03215564PF12796
Domain-

EPHB2 PPFIA2 TNKS

3.96e-031065631.10.150.50
DomainRRM_dom

SYNJ1 ELAVL4 PABPC1L RAVER1

4.76e-03227564IPR000504
DomainAnk

ANK1 TNKS AGAP7P AGAP4

4.84e-03228564PF00023
DomainPH

ARHGAP9 PLEKHG2 AGAP7P AGAP4

4.91e-03229564PF00169
DomainRRM

SYNJ1 ELAVL4 PABPC1L RAVER1

4.99e-03230564PS50102
DomainSAM/pointed

EPHB2 PPFIA2 TNKS

5.22e-03117563IPR013761
Domain-

SYNJ1 ELAVL4 PABPC1L RAVER1

6.13e-032445643.30.70.330
Domain-

ARHGAP9 PLEKHG2 AGAP4 AGAP6 RGS12

6.24e-033915652.30.29.30
Domain-

ANK1 TNKS AGAP4 AGAP6

6.49e-032485641.25.40.20
DomainSAM_2

PPFIA2 TNKS

7.37e-0343562PF07647
DomainNucleotide-bd_a/b_plait

SYNJ1 ELAVL4 PABPC1L RAVER1

7.45e-03258564IPR012677
PathwayREACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES

ALOXE3 ALOX12 ALOX15

7.35e-077403M27139
PathwayREACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES

ALOXE3 ALOX12 ALOX15

7.35e-077403MM14860
PathwayWP_METABOLISM_OF_ALPHALINOLENIC_ACID

ALOX12 ALOX15

1.17e-046402M39844
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS

NCOR1 NCOA1

2.79e-049402M29809
PathwayWP_OCTADECANOID_FORMATION_FROM_LINOLEIC_ACID

ALOXE3 ALOX15

5.09e-0412402M48064
PathwayWP_OMEGA6FATTY_ACIDS_IN_SENESCENCE

ALOXE3 ALOX12 ALOX15

5.57e-0457403M48332
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

ALOXE3 ALOX12 ALOX15

6.16e-0459403M27140
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

ALOXE3 ALOX12 ALOX15

6.80e-0461403MM14861
Pubmed

Expression of inactive glutathione peroxidase 4 leads to embryonic lethality, and inactivation of the Alox15 gene does not rescue such knock-in mice.

ALOXE3 ALOX12 ALOX15

8.77e-08658325313597
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CEP104 NCAPD3 FNBP4 FNDC3A RPRD2 AGAP7P AGAP4 AGAP6 WNK2

2.24e-0752958914621295
Pubmed

Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways.

MAP2K3 ALOX12 ALOX15

2.45e-07858319713213
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP7P AGAP4 AGAP6

3.67e-07958312640130
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP7P AGAP4 AGAP6

5.24e-071058320664521
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP7P AGAP4 AGAP6

7.19e-071158315381706
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP7P AGAP4 AGAP6

1.24e-061358327713690
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP7P AGAP4 AGAP6

1.58e-061458322453919
Pubmed

Emerging role of 12/15-Lipoxygenase (ALOX15) in human pathologies.

ALOX12 ALOX15

2.73e-06258230472260
Pubmed

Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway.

ALOX12 ALOX15

2.73e-06258219373248
Pubmed

Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells.

ALOX12 ALOX15

2.73e-06258230792307
Pubmed

Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.

ALOX12 ALOX15

2.73e-06258225251155
Pubmed

A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense.

ALOX12 ALOX15

2.73e-06258215708862
Pubmed

Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells.

ALOX12 ALOX15

2.73e-06258219095999
Pubmed

Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects.

ALOX12 ALOX15

2.73e-06258221094135
Pubmed

Enhancement role of host 12/15-lipoxygenase in melanoma progression.

ALOX12 ALOX15

2.73e-06258223664097
Pubmed

Lipoxygenase metabolites are mediators of PTH-dependent human osteoblast growth.

ALOX12 ALOX15

2.73e-06258218187376
Pubmed

EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation.

ALOX12 ALOX15

2.73e-06258221220563
Pubmed

12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.

ALOX12 ALOX15

2.73e-06258223528921
Pubmed

Polymorphisms in the human ALOX12 and ALOX15 genes are associated with peak bone mineral density in Chinese nuclear families.

ALOX12 ALOX15

2.73e-06258222089472
Pubmed

Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis.

ALOX12 ALOX15

2.73e-06258232760397
Pubmed

Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of diabetic cardiomyopathy.

ALOX12 ALOX15

2.73e-06258225187369
Pubmed

12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response.

ALOX12 ALOX15

2.73e-06258222215650
Pubmed

12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.

ALOX12 ALOX15

2.73e-06258219787041
Pubmed

Isotope sensitive branching and kinetic isotope effects in the reaction of deuterated arachidonic acids with human 12- and 15-lipoxygenases.

ALOX12 ALOX15

2.73e-06258218547056
Pubmed

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet.

ALOX12 ALOX15

2.73e-06258218780776
Pubmed

Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid.

ALOX12 ALOX15

2.73e-06258219469483
Pubmed

The evolutionary hypothesis of reaction specificity of mammalian ALOX15 orthologs.

ALOX12 ALOX15

2.73e-06258230237084
Pubmed

12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress.

ALOX12 ALOX15

2.73e-06258215111312
Pubmed

Polymorphisms in ALOX12, but not ALOX15, are significantly associated with BMD in postmenopausal women.

ALOX12 ALOX15

2.73e-06258217520163
Pubmed

Human ALOX12, but not ALOX15, is associated with BMD in white men and women.

ALOX12 ALOX15

2.73e-06258216598376
Pubmed

Expression of 12/15-lipoxygenase attenuates intracellular lipid deposition during in vitro foam cell formation.

ALOX12 ALOX15

2.73e-06258215681297
Pubmed

Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase.

ALOX12 ALOX15

2.73e-06258220570249
Pubmed

Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators.

ALOX12 ALOX15

2.73e-06258232324389
Pubmed

EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1.

EPHB2 SYNJ1

2.73e-06258215821731
Pubmed

Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection.

ALOX12 ALOX15

2.73e-06258215879104
Pubmed

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

ALOX12 ALOX15

2.73e-06258229184033
Pubmed

The thyroid axis is regulated by NCoR1 via its actions in the pituitary.

NCOR1 NDOR1

2.73e-06258222878400
Pubmed

Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice.

ALOX12 ALOX15

2.73e-06258210330425
Pubmed

Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes.

ALOX12 ALOX15

2.73e-06258218755188
Pubmed

12-Lipoxygenase isoenzymes in mouse skin tumor development.

ALOX12 ALOX15

2.73e-0625827576099
Pubmed

Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin.

ALOXE3 ALOX12

2.73e-06258217045234
Pubmed

The 12/15-lipoxygenase as an emerging therapeutic target for Alzheimer's disease.

ALOX12 ALOX15

2.73e-06258225708815
Pubmed

Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction.

ALOX12 ALOX15

2.73e-06258225293588
Pubmed

Kinetic investigations of the rate-limiting step in human 12- and 15-lipoxygenase.

ALOX12 ALOX15

2.73e-06258212731864
Pubmed

The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis.

ALOX12 ALOX15

2.73e-06258222267335
Pubmed

Lack of association of ALOX12 and ALOX15 polymorphisms with aspirin-exacerbated respiratory disease in Korean patients.

ALOX12 ALOX15

2.73e-06258219663136
Pubmed

12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.

ALOX12 ALOX15

2.73e-06258219675173
Pubmed

Overexpression of 12/15-lipoxygenase increases anxiety behavior in female mice.

ALOX12 ALOX15

2.73e-06258224300237
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

NCOR1 MAP4K3 FNBP4 AGAP7P MED13L AGAP4 AGAP6 CNOT2

2.94e-0653658815840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

NCOR1 MAP4K3 FNBP4 AGAP7P MED13L AGAP4 AGAP6 CNOT2

3.03e-0653858810512203
Pubmed

Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.

EPHB2 MKI67 ELAVL4

7.61e-062358325480914
Pubmed

Human 5-, 12- and 15-lipoxygenase-1 coexist in kidney but show opposite trends and their balance changes in cancer.

ALOX12 ALOX15

8.19e-06358222825379
Pubmed

Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation.

ALOXE3 ALOX15

8.19e-06358222832496
Pubmed

5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.

ALOX12 ALOX15

8.19e-06358218346986
Pubmed

Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.

ALOX12 ALOX15

8.19e-06358222279185
Pubmed

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.

NCOR1 NCOA1

8.19e-06358224550004
Pubmed

Nuclear receptor coregulators differentially modulate induction and glucocorticoid receptor-mediated repression of the corticotropin-releasing hormone gene.

NCOR1 NCOA1

8.19e-06358218006628
Pubmed

Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase.

ALOX12 ALOX15

8.19e-06358215328042
Pubmed

Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).

ALOX12 ALOX15

8.19e-06358219752233
Pubmed

Loss of ASP but not ROPN1 reduces mammalian ciliary motility.

ROPN1B ROPN1

8.19e-06358222021175
Pubmed

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.

NCOR1 NDOR1

8.19e-06358231404087
Pubmed

Smooth muscle-specific expression of calcium-independent phospholipase A2β (iPLA2β) participates in the initiation and early progression of vascular inflammation and neointima formation.

ALOX12 ALOX15

8.19e-06358222637477
Pubmed

Transcriptional regulation of β-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments.

ALOX12 ALOX15

8.19e-06358222275252
Pubmed

Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages.

ALOX12 ALOX15

8.19e-06358218296557
Pubmed

Relationship between 12/15-lipoxygenase and COX-2 in mesangial cells: potential role in diabetic nephropathy.

ALOX12 ALOX15

8.19e-06358216514433
Pubmed

Following experimental stroke, the recovering brain is vulnerable to lipoxygenase-dependent semaphorin signaling.

ALOX12 ALOX15

8.19e-06358223070608
Pubmed

Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity.

ALOX12 ALOX15

8.19e-06358230944221
Pubmed

5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.

ALOX12 ALOX15

8.19e-06358230407793
Pubmed

Insulin-like growth factor I reduces lipid oxidation and foam cell formation via downregulation of 12/15-lipoxygenase.

ALOX12 ALOX15

8.19e-06358225549319
Pubmed

Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity.

ROPN1B ROPN1

8.19e-06358223303679
Pubmed

Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis.

NCOR1 NDOR1

8.19e-06358234390859
Pubmed

Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine 735.

NCOR1 NCOA1

8.19e-06358212569182
Pubmed

The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.

ALOX12 ALOX15

8.19e-0635828944751
Pubmed

12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis.

ALOX12 ALOX15

8.19e-06358219822654
Pubmed

Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability.

ALOX12 ALOX15

8.19e-06358223079635
Pubmed

Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.

NCOR1 NCOA1

8.19e-0635829804773
Pubmed

Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine.

ALOX12 ALOX15

8.19e-06358218311922
Pubmed

Effects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAs.

ALOX12 ALOX15

8.19e-06358215576842
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

NCOR1 SYNJ1 MAP4K3 BACH2 GTSE1 PLEKHG2 RGS12 RAVER1 FTSJ3

1.12e-0585358928718761
Pubmed

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.

NCAPD3 GTSE1 MKI67 ELAVL4

1.40e-058758433798452
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

NCOR1 GTSE1 MKI67 RPRD2 RAVER1

1.43e-0518458532908313
Pubmed

Functional characterization of genetic enzyme variations in human lipoxygenases.

ALOX12 ALOX15

1.64e-05458224282679
Pubmed

cDNA cloning of a 8-lipoxygenase and a novel epidermis-type lipoxygenase from phorbol ester-treated mouse skin.

ALOX12 ALOX15

1.64e-0545829518531
Pubmed

Characterization of human 12-lipoxygenase genes.

ALOX12 ALOX15

1.64e-0545821570320
Pubmed

Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia.

ALOX12 ALOX15

1.64e-05458212122008
Pubmed

Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.

ALOX12 ALOX15

1.64e-05458225698732
Pubmed

NCoR1 and SMRT play unique roles in thyroid hormone action in vivo.

NCOR1 NDOR1

1.64e-05458225421714
Pubmed

cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases.

ALOX12 ALOX15

1.64e-0545828188678
Pubmed

Increased nuclear apoptosis-inducing factor after transient focal ischemia: a 12/15-lipoxygenase-dependent organelle damage pathway.

ALOX12 ALOX15

1.64e-05458220068575
Pubmed

Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis.

ALOX12 ALOX15

1.64e-05458219819949
Pubmed

Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella.

ROPN1B ROPN1

1.64e-05458210591629
Pubmed

Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.

ALOX12 ALOX15

1.64e-05458219509298
Pubmed

Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells.

NCOR1 NCOA1

1.64e-05458215256534
Pubmed

A novel natural mutation in the thyroid hormone receptor defines a dual functional domain that exchanges nuclear receptor corepressors and coactivators.

NCOR1 NCOA1

1.64e-0545829849963
Pubmed

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.

PPM1D NCOA1

1.64e-05458216352595
Pubmed

Agonist-triggered modulation of the activated and silent state of the vitamin D(3) receptor by interaction with co-repressors and co-activators.

NCOR1 NCOA1

1.64e-05458211124027
Pubmed

A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.

NCOR1 NCOA1

1.64e-05458210339548
Pubmed

Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.

ALOX12 ALOX15

1.64e-05458220592751
Pubmed

Nuclear receptor coregulator SNP discovery and impact on breast cancer risk.

NCOR1 NCOA1

1.64e-05458220003447
Cytoband17p13.1

ALOXE3 SLC16A11 ALOX12

4.61e-0411858317p13.1
Cytoband10q11.23

AGAP7P AGAP6

8.08e-043358210q11.23
CytobandEnsembl 112 genes in cytogenetic band chr17p13

ALOXE3 SLC16A11 ALOX12 ALOX15

9.76e-04346584chr17p13
CytobandEnsembl 112 genes in cytogenetic band chr10q11

AGAP7P AGAP4 AGAP6

1.77e-03188583chr10q11
Cytoband1q32

DTL SOX13

1.78e-03495821q32
CytobandEnsembl 112 genes in cytogenetic band chr12q15

CPM CNOT2

2.31e-0356582chr12q15
GeneFamilyArachidonate lipoxygenases

ALOXE3 ALOX12 ALOX15

1.71e-076383407
GeneFamilyArfGAPs

AGAP7P AGAP4 AGAP6

4.47e-0533383395
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGAP9 PLEKHG2 AGAP7P AGAP4 AGAP6

6.76e-05206385682
GeneFamilyAnkyrin repeat domain containing

ANK1 TNKS AGAP7P AGAP4 AGAP6

1.44e-04242385403
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP4 AGAP6

5.73e-04173821291
GeneFamilySterile alpha motif domain containing

EPHB2 PPFIA2 TNKS

8.31e-0488383760
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCAPD3 CARMIL3 GTSE1 DTL MKI67

4.28e-061855859d424a8608b339dd6129c58d87626678d4ec4af7
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

NCAPD3 ANK1 GTSE1 DTL MKI67

4.99e-06191585bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 BACH2 GTSE1 MKI67 CPM

5.52e-06195585294c74336fafc1bad237d851efb4a487475078eb
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

NCAPD3 ANK1 GTSE1 DTL MKI67

5.52e-06195585764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 BACH2 GTSE1 MKI67 CPM

5.52e-061955855749ea833be84e262e3d0a4fe1a9a373f0ef545f
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANK1 GTSE1 MKI67 MAP2K3 ALOX12

6.25e-06200585b5f2892bc45fda5ae05e269b840305a608a07c37
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANK1 PPFIA2 MKI67 ALOX12 WNK2

6.25e-06200585326cae37cacd94b423a6ac8873ea56c5abaf0a0b
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANK1 GTSE1 MKI67 MAP2K3 ALOX12

6.25e-062005859ce1f91991637fc3af0f6a80a85e1a44276fe412
ToppCellLung_Parenchyma-Severe-Hematopoietic|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANK1 GTSE1 MKI67 MAP2K3 ALOX12

6.25e-06200585fdf3e60cf94f398a56c0fa72813d0459f5ce081b
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANK1 GTSE1 MKI67 MAP2K3 ALOX12

6.25e-06200585199165be1aef8497af71b74690a11de18fbe073c
ToppCellParenchyma_COVID-19-Stromal-TX-Erythrocytes|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ANK1 GTSE1 MKI67 MAP2K3 ALOX12

6.25e-06200585a9edac2f5e009662df452ec032a80e855cdac28f
ToppCell15-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

GTSE1 DTL MKI67 ARHGAP9

3.94e-05146584ca722a89c6601e78f253d9484d01931f26161820
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GTSE1 DTL MKI67 ROPN1B

4.15e-0514858418cfecd6ae20edb74f5d44ba759909df356acf3a
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP4K3 GTSE1 MKI67 RPRD2

5.10e-05156584d411116d54add2d4fe649a97ac54cb94c085312f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 GTSE1 DTL MKI67

6.05e-05163584466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D RASGRP4 GTSE1 DTL

6.34e-05165584e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D RASGRP4 GTSE1 DTL

6.34e-05165584b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D RASGRP4 GTSE1 DTL

6.34e-05165584d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 GTSE1 DTL MKI67

6.64e-05167584bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP4K3 SLC16A11 TNKS SEMA3G

6.96e-051695844e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

GTSE1 DTL MKI67 ELAVL4

7.12e-0517058473601c873b177d5d134618d8e228c51381119f7d
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MKI67 ARHGAP9 PABPC1L

7.12e-05170584d582087a983fe20d811d92f0de0458f3cfd71d2b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 GTSE1 DTL MKI67

7.12e-0517058421bfe070e63722672176052b386167ea4c3dc4e5
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MKI67 ARHGAP9 PABPC1L

7.12e-05170584dfbe7ba11b867a4e10fa915f282a2e5cb2f5fb8c
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GTSE1 DTL MKI67 SEMA3G

7.28e-0517158413126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid-new-cluster|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MKI67 ARHGAP9 PABPC1L

7.28e-05171584d0d92eb5152410c3b4dd4a3f1dc3cca0e18a85fd
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 GTSE1 DTL MKI67

7.45e-051725842b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

NCAPD3 GTSE1 DTL MKI67

7.62e-051735848a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 GTSE1 DTL MKI67

7.79e-0517458484da9faff088d05233183b425385beb054c92d1b
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 DTL MKI67 SEMA3G

7.79e-05174584c988471207ba06195bc3e41056435e8c31c20bbe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GTSE1 DTL MKI67 ELAVL4

7.96e-05175584f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellwk_20-22-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ANK1 GTSE1 MKI67 MAP2K3

8.14e-0517658498814f0a67411b2f7b25dc489b2aadb77f45a853
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

NCAPD3 GTSE1 DTL MKI67

8.14e-05176584a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NCAPD3 GTSE1 DTL MKI67

8.51e-05178584c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCellHealthy_donor-Plasmablast|Healthy_donor / disease group, cell group and cell class (v2)

DTL MKI67 SEMA3G WNK2

8.51e-05178584388b8b4fa20dcc6e9ae4b06118e20b2c20c52bde
ToppCellwk_08-11-Epithelial-PNS-Proliferating_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KIAA1755 ROPN1B ROPN1 ALOX15

8.69e-05179584ab23fee9adab1e63d5b5cd9faba6b9a92beef425
ToppCellControl-Developping_Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GTSE1 DTL MKI67 SEMA3G

8.69e-051795849383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 GTSE1 DTL MKI67

8.88e-05180584401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 GTSE1 DTL MKI67

8.88e-05180584f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAPD3 GTSE1 DTL MKI67

9.07e-0518158473b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

NCAPD3 GTSE1 DTL MKI67

9.27e-05182584b1e66ccd5f33b4801f1cafddf97f5fc0c6dba8d1
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GTSE1 MKI67 ALOX12 CNOT2

9.27e-05182584007fa56ed8b91f9af0df2114c00410b2f6cec8b6
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D CARMIL3 BACH2 ELAVL4

9.47e-05183584bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CARMIL3 GTSE1 DTL MKI67

9.47e-0518358454782c2e23bbeca5b683aa931393b1118da4aa37
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RASGRP4 GTSE1 DTL MKI67

9.47e-05183584f03d87b556a3d50360d4eb6126b3466fe7266677
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSC5D CARMIL3 BACH2 ELAVL4

9.47e-051835844c325ee6da070513097a11445ec95b0415ffd8a2
ToppCellIIF-Lymphocyte-T_NK-T_NK_proliferative|IIF / Disease, Lineage and Cell Type

GTSE1 DTL MKI67 SEMA3G

9.67e-05184584ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH2 GTSE1 MKI67 CPM

1.01e-041865843993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH2 GTSE1 MKI67 CPM

1.01e-04186584ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTSE1 DTL MKI67 ELAVL4

1.03e-041875844d12c70c8ed922fbc8f7b139145611203735cab4
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTSE1 DTL MKI67 ELAVL4

1.03e-04187584e46b49b4053d2d0f3e1d2bcdc380f7f8733cbe07
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTSE1 DTL MKI67 ELAVL4

1.03e-04187584a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTSE1 DTL MKI67 ELAVL4

1.03e-0418758438ee33295a21db4aae5ba085df033db9693e41c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 GTSE1 DTL MKI67

1.03e-04187584057569c9437219ecc396aa6e673b1178a2273837
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTSE1 DTL MKI67 ELAVL4

1.03e-04187584e851ee46a6b4068a7bd7602ee183c0ace50ee4dd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTSE1 DTL MKI67 ELAVL4

1.03e-04187584dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

XRRA1 ITPRID2 AGAP4 RGS12

1.05e-041885842c4e791df69a9df29922f9117e5cac7787c129ce
ToppCellMatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)|MatrixFB / shred on cell class and cell subclass (v4)

NCAPD3 GTSE1 DTL MKI67

1.05e-04188584b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

XRRA1 ITPRID2 AGAP4 RGS12

1.05e-04188584b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCellNS-critical-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NCAPD3 GTSE1 DTL MKI67

1.07e-04189584d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RASGRP4 SYNJ1 ITPRID2 ALOX12

1.07e-04189584a2f4f1dd5452f7efb7427919a0b90875cf2e1dc7
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RASGRP4 SYNJ1 ITPRID2 ALOX12

1.07e-0418958454a45b0cb7dea01caf1cf0a2664c40e5779a0b61
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 GTSE1 DTL MKI67

1.09e-0419058431de1727822e9818652946dfb962daee77ffad68
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

NCAPD3 GTSE1 DTL MKI67

1.12e-04191584210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCellMild-T/NK_proliferative|World / Disease group and Cell class

NCAPD3 GTSE1 DTL MKI67

1.12e-041915849dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Cycling_Myeloid-Mac|GI_small-bowel / Manually curated celltypes from each tissue

GTSE1 DTL MKI67 ALOX12

1.12e-04191584c3944332c5226b0113f8aa9ac07837b755606c6c
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

GTSE1 MKI67 RNF213 CPM

1.14e-04192584a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l12-14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCAPD3 GTSE1 MKI67 WNK2

1.14e-0419258452d0aa51e3b6ab3608a5f40bdde9f8134b3afd94
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

NCOR1 GTSE1 MKI67 PABPC1L

1.14e-041925849cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 GTSE1 DTL MKI67

1.14e-04192584e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCellNS-moderate-d_0-4-Lymphoid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GTSE1 DTL MKI67 ARHGAP9

1.14e-04192584905217dcfc843d3469e9e71bd33707863b14cc82
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROPN1B SEMA3G ROPN1 ALOX15

1.16e-041935843ea6b103e35bbb276e95301999618558fa3e38b1
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NCAPD3 GTSE1 DTL MKI67

1.16e-041935844b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 GTSE1 DTL MKI67

1.16e-04193584cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAPD3 GTSE1 DTL MKI67

1.16e-04193584e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NCAPD3 GTSE1 DTL MKI67

1.19e-04194584f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|World / Lineage, cell class and subclass

ANK1 GTSE1 DTL MKI67

1.19e-04194584008bb0072f414a48d052429101bdc990ee4f80c2
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

NCAPD3 GTSE1 DTL MKI67

1.19e-04194584a12b64945e10f00aa983678a02586c59badc1570
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCOR1 NCAPD3 RNF213 RAVER1

1.21e-0419558483c125223e7ca0f08a31414b3a16347912564765
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 DTL MKI67 RAVER1

1.21e-04195584be8db0a22ef8ce24819f790b0bd93670e73af76f
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

NCAPD3 GTSE1 DTL MKI67

1.21e-041955847e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FRY ANK1 DTL MKI67

1.21e-04195584c96755d2eb98112b703b5dbee9c88730ace7dcbf
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 SYNJ1 CARMIL3 NCOA1

1.21e-041955843e519cffa6144a62b06124642a14c9ff39b76554
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NCAPD3 GTSE1 DTL MKI67

1.23e-041965849591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NCAPD3 GTSE1 DTL MKI67

1.23e-041965841964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NCAPD3 GTSE1 DTL MKI67

1.23e-0419658434bd155e6d848eb53d613997c0e244535de30ba3
ToppCellsevere_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

NCAPD3 GTSE1 DTL MKI67

1.26e-04197584189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GTSE1 MKI67 ROPN1 RAVER1

1.26e-0419758441bdea47b9b1f6415a866a515d1535ea942fdede
ToppCellMild_COVID-19-T/NK-proliferating_T/NK|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

NCAPD3 GTSE1 DTL MKI67

1.26e-041975845fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NCAPD3 GTSE1 DTL MKI67

1.26e-0419758484ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellHealthy-T/NK_proliferative|World / disease group, cell group and cell class

NCAPD3 GTSE1 DTL MKI67

1.26e-04197584e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCellproximal-Hematologic-Proliferating_Macrophage|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPD3 GTSE1 DTL MKI67

1.26e-041975840b1fa881abbfcc54b322fc27124db3f8947af016
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAPD3 GTSE1 DTL MKI67

1.26e-041975847eb4c1cffd0366204af7e63adc8f751685601a94
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCAPD3 GTSE1 DTL MKI67

1.26e-04197584d7a9296092153cf66426911fecd810f0c1ef978e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCAPD3 GTSE1 DTL MKI67

1.26e-04197584dcff23240bb7cb652d7426b29355aa74442ef6fc
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NCAPD3 GTSE1 DTL MKI67

1.26e-04197584434a5686a103bb766e0d80038413f0e12ea3981a
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GTSE1 DTL MKI67 ELAVL4

1.26e-041975840a404b4494a2246d5a92299235056f0fda4d2b48
ToppCellMild-Lymphoid-T-Proliferating_T|Mild / Condition, Lineage, Cell class and cell subclass

NCAPD3 GTSE1 DTL MKI67

1.26e-04197584794517c70089da109f4c6489fe406c0ba6882b76
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NCAPD3 GTSE1 DTL MKI67

1.26e-041975846bddfa199ca812d9e518eaa02c3d4fb67e9f5b16
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NCAPD3 GTSE1 DTL MKI67

1.26e-04197584c0a71a9452febda433bc544e4ac0a79c43dcf13e
Drug5-HEPE

FNDC3A ALOXE3 ALOX12 ALOX15

3.72e-0814584CID000001766
DrugAC1L3X17

FNDC3A ALOXE3 ALOX12 ALOX15

4.61e-0725584CID000123644
Drug12-IODE

ALOXE3 ALOX12 ALOX15

5.45e-077583CID006450050
Drugcolneleic acid

ALOXE3 ALOX12 ALOX15

8.71e-078583CID006441681
DrughtyA

ALOXE3 ALOX12 ALOX15

8.71e-078583CID000152267
Drug14,15-leukotriene A4

ALOXE3 ALOX12 ALOX15

1.30e-069583CID006439604
Drugoctadeca-9,12-dien-1-ol

ALOXE3 ALOX12 ALOX15

1.30e-069583CID000068168
Drug8,15-diHPETE

ALOXE3 ALOX12 ALOX15

1.30e-069583CID005283181
Drug13-hydroxylinoleic acid

ALOXE3 ALOX12 ALOX15

1.30e-069583CID006438633
DrugAC1NSXHC

ALOXE3 ALOX12 ALOX15

1.30e-069583CID005371969
DrugU-66,855

ALOXE3 ALOX12 ALOX15

1.30e-069583CID000127235
DrugODYA

ALOXE3 ALOX12 ALOX15

1.30e-069583CID000001931
Drug9-HPODE

ALOXE3 ALOX12 ALOX15

1.86e-0610583CID000001928
Drug1,4-pentadiene

ALOXE3 ALOX12 ALOX15

1.86e-0610583CID000011587
Drugacetone phenylhydrazone

ALOXE3 ALOX12 ALOX15

2.55e-0611583CID000066026
DrugIty A

ALOXE3 ALOX12 ALOX15

2.55e-0611583CID000188274
Drugnonenal

ALOXE3 ALOX12 ALOX15

3.40e-0612583CID003015503
DrugAC1NR1Q2

ALOXE3 ALOX12 ALOX15

4.41e-0613583CID005283190
DrugAC1L1BGZ

ALOXE3 ALOX12 ALOX15

4.41e-0613583CID000001435
Drug9-HETE

ALOXE3 ALOX12 ALOX15

4.41e-0613583CID000001926
DrugICI207968

ALOXE3 ALOX12 ALOX15

4.41e-0613583CID000129095
DrugAC1O4E1A

ALOXE3 ALOX12 ALOX15

4.41e-0613583CID006365736
DrugAC1NR1LB

ALOXE3 ALOX12 ALOX15

5.60e-0614583CID005283131
Drugoxphaman

ALOXE3 ALOX12 ALOX15

5.60e-0614583CID005464022
Drugtimegadine

ALOXE3 ALOX12 ALOX15

5.60e-0614583CID000068902
Drug17-HdoHE

ALOXE3 ALOX12 ALOX15

5.60e-0614583CID006439179
Drug8R-HpETE

ALOXE3 ALOX12 ALOX15

6.98e-0615583CID005283170
DrugHex-3-enyl acetate

ALOXE3 ALOX12 ALOX15

6.98e-0615583CID000015574
Drug8(S),15(S)-diHETE

ALOXE3 ALOX12 ALOX15

6.98e-0615583CID000001897
Drug13-HpOTrE

ALOXE3 ALOX12 ALOX15

6.98e-0615583CID005282866
DrugAC1NR1M2

ALOXE3 ALOX12 ALOX15

8.58e-0616583CID005283140
Drug12R-HETrE

ALOXE3 ALOX12 ALOX15

8.58e-0616583CID005283149
Drugperoxylinolenic acid

ALOXE3 ALOX12 ALOX15

8.58e-0616583CID006439905
Drughex-3-enal

ALOXE3 ALOX12 ALOX15

8.58e-0616583CID000023234
Drug5,15-diHETE

ALOXE3 ALOX12 ALOX15

1.04e-0517583CID005283158
Drugcirsiliol

ALOXE3 ALOX12 ALOX15

1.04e-0517583CID000160237
DrugFPL 57231

ALOXE3 ALOX12 ALOX15

1.25e-0518583CID000122212
Drug3-nonenal

ALOXE3 ALOX12 ALOX15

1.25e-0518583CID005283336
DrugBW540C

ALOXE3 ALOX12 ALOX15

1.25e-0518583CID000134372
DrugAC1O5PL5

ALOXE3 ALOX12 ALOX15

1.25e-0518583CID006438380
DrugL-651,392

ALOXE3 ALOX12 ALOX15

1.73e-0520583CID000122182
DrugTMK777

ALOXE3 ALOX12 ALOX15

1.73e-0520583CID006438911
DrugAC1L2P35

ALOXE3 ALOX12 ALOX15

1.73e-0520583CID000125736
Drug13(R)-hydroxy-octadeca-(9Z,11E,15Z)-trienoic acid

ALOX12 ALOX15

1.91e-053582CID000643726
DrugAC1O5S1P

ALOXE3 ALOX12 ALOX15

2.02e-0521583CID006439617
DrugAC1NRAUB

ALOXE3 ALOX12 ALOX15

2.02e-0521583CID005288098
Drug20-carboxyleukotriene B4

ALOXE3 ALOX12 ALOX15

2.02e-0521583CID000001588
DrugBM 13.177

ALOXE3 ALOX12 ALOX15

2.33e-0522583CID000051550
Drug5,8,11-eicosatrienoic acid

ALOXE3 ALOX12 ALOX15

2.33e-0522583CID000004028
DrugCGS 8515

ALOXE3 ALOX12 ALOX15

2.33e-0522583CID000163944
Drugdiethylcarbamazine

ALOXE3 ALOX12 ALOX15

2.33e-0522583CID000003052
DrugL-656,224

ALOXE3 ALOX12 ALOX15

2.68e-0523583CID000128132
DrugAC1NSYHD

ALOXE3 ALOX12 ALOX15

2.68e-0523583CID005319705
Drugoctadecadienoic acid

ALOXE3 ALOX12 ALOX15

2.68e-0523583CID005312457
Drug13-hydroperoxylinoleic acid

ALOXE3 ALOX12 ALOX15

3.47e-0525583CID006438144
Drugpinolenic acid

ALOXE3 ALOX12 ALOX15

3.47e-0525583CID005312493
Drugpentylhydrazine

ALOX12 ALOX15

3.81e-054582CID000014246
DrugAC1NSP79

ALOX12 ALOX15

3.81e-054582CID005313497
DrugT-22083

ALOX12 ALOX15

3.81e-054582CID006439700
DrugAC1NR0V5

ALOX12 ALOX15

3.81e-054582CID005282813
DrugAC1L3WDO

ALOXE3 ALOX12 ALOX15

3.91e-0526583CID000123344
Drug11-HETE

ALOXE3 ALOX12 ALOX15

3.91e-0526583CID000001406
Drug20-hydroxyleukotriene B4

ALOXE3 ALOX12 ALOX15

3.91e-0526583CID000001589
Drug8-HETE

ALOXE3 ALOX12 ALOX15

3.91e-0526583CID000001898
DrugBhpp

ALOXE3 ALOX12 ALOX15

4.39e-0527583CID000164136
DrugBW A4C

ALOXE3 ALOX12 ALOX15

4.39e-0527583CID006438354
DrugSC-41930

ALOXE3 ALOX12 ALOX15

4.39e-0527583CID000114999
DrugAC1L1G9E

ALOXE3 ALOX12 ALOX15

4.91e-0528583CID000003586
DrugL-649,923

ALOXE3 ALOX12 ALOX15

4.91e-0528583CID000119331
Drug13-epi-12-oxo-phytodienoic acid

ALOXE3 ALOX12 ALOX15

5.47e-0529583CID000188366
Drugnafazatrom

ALOXE3 ALOX12 ALOX15

5.47e-0529583CID000042923
Drug14-hydroxydocosahexaenoic acid

ALOX12 ALOX15

6.35e-055582CID006439735
DrugN-(3-phenoxycinnamyl)acetohydroxamic acid

ALOX12 ALOX15

6.35e-055582ctd:C056614
Drugartonin E

ALOX12 ALOX15

6.35e-055582CID005481962
DrugAC1L2VAC

ALOX12 ALOX15

6.35e-055582CID000129261
Drug12-hydroxyheptadecatrienoic acid

ALOXE3 ALOX12 ALOX15

6.70e-0531583CID000001414
Drug(Z)-7-[(1R,2R,3R)-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-3-methyl-5-oxocyclopentyl]hept-5-enoic acid

ALOXE3 ALOX12 ALOX15

8.11e-0533583CID009548573
DrugICI 198,615

ALOXE3 ALOX12 ALOX15

8.88e-0534583CID000115219
DrugAC1L571W

ALOX12 ALOX15

9.50e-056582CID000171201
Drugcolnelenic acid

ALOX12 ALOX15

9.50e-056582CID006441679
Drugisamoxole

ALOX12 ALOX15

9.50e-056582CID000042118
Drug1-oleoyl-2-DHA-PC

ALOX12 ALOX15

9.50e-056582CID006438829
DrugCPHU

ALOX12 ALOX15

9.50e-056582CID000124471
DrugBW A797C

ALOX12 ALOX15

9.50e-056582CID006439067
DrugAC1MQ2IQ

ALOX12 ALOX15

9.50e-056582CID003394960
Drugtsuwabukinonol

ALOXE3 ALOX12 ALOX15

1.15e-0437583CID006440419
DrugsIL-4R

ALOXE3 ALOX12 ALOX15

1.15e-0437583CID000059757
DrugRvD1

ALOX12 ALOX15

1.33e-047582CID016061135
Druglupenone

ALOX12 ALOX15

1.33e-047582CID000092158
Drugdicranin

ALOX12 ALOX15

1.33e-047582CID006441084
DrugBay 08276

ALOX12 ALOX15

1.33e-047582CID000134943
Drug11,14,15-THET

ALOXE3 ALOX12 ALOX15

1.34e-0439583CID006439531
Drugtricarbon

ALOXE3 ALOX12 ALOX15

1.34e-0439583CID006432003
DrugREV 5901

ALOXE3 ALOX12 ALOX15

1.34e-0439583CID000005059
DrugHarmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; PC3; HT_HG-U133A

BACH2 NCOA1 N4BP1 PKD1L1-AS1 MUC2

1.36e-041945855076_DN
DrugLorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; PC3; HT_HG-U133A

BACH2 TNKS PKD1L1-AS1 MUC2 RGS12

1.46e-041975854658_UP
Drugindomethacin, USP; Down 200; 100uM; SKMEL5; HG-U133A

NDOR1 ELAVL4 FNDC3A SOX13 RGS12

1.46e-04197585503_DN
Druggenistein; Down 200; 10uM; MCF7; HT_HG-U133A_EA

NCOR1 GTSE1 NCOA1 MAP2K3 SOX13

1.49e-041985851073_DN
DrugHyoscyamine (L) [101-31-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A

NDOR1 FNDC3A ALOXE3 SEMA3G PKD1L1-AS1

1.49e-041985852271_UP
DrugBacitracin [1405-87-4]; Up 200; 2.8uM; HL60; HT_HG-U133A

EPHB2 ELAVL4 CPM PKD1L1-AS1 RGS12

1.49e-041985853109_UP
Diseasecerebral palsy (implicated_via_orthology)

AGAP7P AGAP4 AGAP6

7.29e-0710553DOID:1969 (implicated_via_orthology)
Diseasemucositis (biomarker_via_orthology)

MKI67 MUC2

3.40e-055552DOID:0080178 (biomarker_via_orthology)
DiseaseNasal Cavity Polyp

BACH2 NCOA1 ALOX15

1.50e-0455553EFO_1000391
DiseaseBarrett's esophagus (is_marker_for)

MKI67 MUC2

1.86e-0411552DOID:9206 (is_marker_for)
Diseasehypothyroidism (biomarker_via_orthology)

NCOR1 NCOA1 ELAVL4

4.55e-0480553DOID:1459 (biomarker_via_orthology)
Diseaseneutrophil percentage of granulocytes

RASGRP4 BACH2 N4BP1 ALOX15

8.70e-04228554EFO_0007994
Diseasebasophil count, eosinophil count

RASGRP4 BACH2 N4BP1 ALOX15

1.07e-03241554EFO_0004842, EFO_0005090
Diseasecolon cancer (biomarker_via_orthology)

MKI67 MUC2

2.42e-0339552DOID:219 (biomarker_via_orthology)
Diseasepsoriasis (is_marker_for)

MKI67 ALOX12

3.07e-0344552DOID:8893 (is_marker_for)
DiseaseEndometrioma

NCOR1 NCOA1 CPM

3.40e-03161553C0269102
DiseaseEndometriosis

NCOR1 NCOA1 CPM

3.40e-03161553C0014175
DiseaseCrohn Disease

BACH2 MUC2

3.95e-0350552C0010346
Diseaseinterferon gamma measurement

EPHB2 ALOX12

4.10e-0351552EFO_0008165
Diseasesusceptibility to common cold measurement

FNDC3A SLC16A11

4.59e-0354552EFO_0008417
DiseasePeripheral Nervous System Diseases

MKI67 ALOX12

4.59e-0354552C4721453
Diseasebreast cancer (is_marker_for)

MKI67 MAP2K3 ALOX12

5.01e-03185553DOID:1612 (is_marker_for)
Diseasesystemic lupus erythematosus, COVID-19

ARHGAP9 RAVER1

5.27e-0358552MONDO_0007915, MONDO_0100096
DiseaseMalignant neoplasm of prostate

EPHB2 NCOR1 NCOA1 RPRD2 ALOXE3

5.75e-03616555C0376358

Protein segments in the cluster

PeptideGeneStartEntry
KPCFSQPTSNMEPPK

TDRD5

236

Q8NAT2
PPTANTPTPVCKRSM

AGAP4

211

Q96P64
PGRMRPNTSCPVPIK

BACH2

491

Q9BYV9
SPAIPRIPCAMPETV

ANK1

856

P16157
VKRLMSGPVPPSACP

ELAVL4

261

P26378
PSPVTITPSSMRKIC

DTL

696

Q9NZJ0
LSPPTMNLRPPKSCG

PKD1L1-AS1

21

Q9H7B7
RPACPASMPPTKDNL

ATXN7L2

491

Q5T6C5
PPTANTPTPVCKRSM

AGAP6

211

Q5VW22
PTCCPRPSPAQKAAM

RAVER1

576

Q8IY67
RCPMSGSPAKPSQVP

MAP4K3

461

Q8IVH8
RCFPTPQTAMTPQPA

SLC16A11

16

Q8NCK7
KDPSNCGMPLTPPTS

MED13L

316

Q71F56
PKPMPCPSRNTSSPE

KIAA1755

451

Q5JYT7
PSSMRQPPPQTKGTT

ALOXE3

606

Q9BYJ1
PPPQSTKPSFSAMRR

CARMIL3

1206

Q8ND23
PLDMPCTTIPSAPQA

EPHB2

316

P29323
PMDKCITTPSPPTTT

MUC2

1391

Q02817
VPCPVMDPPSTASSK

RASGRP4

656

Q8TDF6
NAPCTMRLPPPTTKD

ALOX15

556

P16050
IACKSPPPESMDTPT

MKI67

2101

P46013
TCVMTPSPCSTPPVK

PPM1D

406

O15297
NAPCTMRMPPPTTKE

ALOX12

556

P18054
TSQPPRPSCASMVRP

PABPC1L

436

Q4VXU2
GRTPTCSRLAPPPMS

ITPRID2

826

P28290
TPKTMPRAVGSPLCV

GTSE1

526

Q9NYZ3
PDVSSPTRLPQPCSM

NDOR1

281

Q9UHB4
RSGSPCHQKPMPSLP

CEP104

311

O60308
DSIPVSNPSCPMIPL

CPM

401

P14384
MSSPPSSPQKCPSPI

FNDC3A

201

Q9Y2H6
PPTANTPTPVCKRSM

AGAP7P

211

Q5VUJ5
TITETKQPQPLPMPC

FRY

1601

Q5TBA9
CTPVPVTMTATPPLP

RPRD2

416

Q5VT52
MSTLCPPPSPAVAKT

C9orf72

1

Q96LT7
CETSPPPTPRALRMT

PPFIA2

771

O75334
RISCMSKPPAPNPTP

MAP2K3

26

P46734
MAQTDKPTCIPPELP

ROPN1B

1

Q9BZX4
SCMPTMPPIPARSQS

SYNJ1

1371

O43426
VQNPPKPVMTTRPTA

FNBP4

86

Q8N3X1
MDPCNTNPTPMTKPT

NCOA1

781

Q15788
RMLSSTPPTPIACAP

NCOR1

2391

O75376
PSAAPTSTCAPRKMP

SNTN

21

A6NMZ2
PQTPPSCLKTEIMSP

FTSJ3

571

Q8IY81
AKRPTTQPPVMPTTK

SSC5D

636

A1L4H1
PAMSPAVSQPCTPRA

NCAPD3

1306

P42695
PSIICMPKQQPSRQP

CNOT2

171

Q9NZN8
MKQPPATTPPFKTHC

RNF213

296

Q63HN8
PSLKMSSCVPRPPSH

SOX13

311

Q9UN79
SINCGTLPPPMSKIP

RGS12

566

O14924
MAQTDKPTCIPPELP

ROPN1

1

Q9HAT0
MPPEALPTCFKPQAT

TNKS

956

O95271
QASSEQPPPLPRKMC

ARHGAP9

126

Q9BRR9
QPPPLPRKMCRSVST

ARHGAP9

131

Q9BRR9
QPPSTTPCPTVMRAE

USF3

556

Q68DE3
FPRPGVCPSKMTAQP

SEMA3G

376

Q9NS98
MPSIPCLTKIPDVPN

PLEKHG2

626

Q9H7P9
MPCRTIVPNAPATIP

WNK2

871

Q9Y3S1
PLPMACPALSESQPK

XRRA1

756

Q6P2D8
SPHSKPNCSTLSPPM

N4BP1

551

O75113