Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	HEAT_REPEAT	RELCH TOGARAM1 ODAD2 HEATR5B	7.53e-05	70	60	4	PS50077
Domain	Hematopoietin_rcpt_Gp130_CS	CSF3R OSMR	2.11e-04	7	60	2	IPR003529
Domain	HEMATOPO_REC_L_F2	CSF3R OSMR	2.81e-04	8	60	2	PS01353
Domain	DS_RBD	ILF3 SON	2.05e-03	21	60	2	PS50137
Domain	-	ILF3 SON	3.38e-03	27	60	2	3.30.160.20
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	PPARG ABCB1 VDR	8.15e-05	30	40	3	MM15866
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	PPARG ABCB1 VDR	1.09e-04	33	40	3	MM1448
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	PPARG ABCB1 VDR	1.19e-04	34	40	3	M16393
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	PPARG ABCB1 VDR	1.30e-04	35	40	3	M39488
Pubmed	Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia.	GSTT1 ABCB1 VDR	1.88e-07	7	62	3	19005482
Pubmed	TotalPlex gene amplification using bulging primers for pharmacogenetic analysis of acute lymphoblastic leukemia.	GSTT1 ABCB1 VDR	6.42e-07	10	62	3	18385010
Pubmed	SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARγ2.	SIRT7 PPARG	3.13e-06	2	62	2	33955199
Pubmed	1,25-Dihydroxyvitamin D₃ Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPARγ Signaling Pathway.	PPARG VDR	3.13e-06	2	62	2	25961000
Pubmed	Maternal vitamin D deficiency during pregnancy affects expression of adipogenic-regulating genes peroxisome proliferator-activated receptor gamma (PPARγ) and vitamin D receptor (VDR) in lean male mice offspring.	PPARG VDR	3.13e-06	2	62	2	28004271
Pubmed	Involvement of Vitamin D receptor in the intestinal induction of human ABCB1.	ABCB1 VDR	3.13e-06	2	62	2	19460946
Pubmed	1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells.	ABCB1 VDR	3.13e-06	2	62	2	23035695
Pubmed	Reversal of P-glycoprotein-mediated multidrug resistance in SGC7901/VCR cells by PPARgamma activation by troglitazone.	PPARG ABCB1	3.13e-06	2	62	2	20556576
Pubmed	B-cell-specific-peroxisome proliferator-activated receptor γ deficiency augments contact hypersensitivity with impaired regulatory B cells.	CD19 PPARG	3.13e-06	2	62	2	30471095
Pubmed	Increased body mass index but not common vitamin D receptor, peroxisome proliferator-activated receptor γ, or cytokine polymorphisms confers predisposition to posttransplant diabetes.	PPARG VDR	3.13e-06	2	62	2	22129188
Pubmed	PPARγ Modulation of Cytokine-Stimulated MUC16 (CA125) Expression in Breast and Ovarian Cancer-Derived Cells.	MUC16 PPARG	3.13e-06	2	62	2	27292441
Pubmed	Crosstalk between the peroxisome proliferator-activated receptor γ (PPARγ) and the vitamin D receptor (VDR) in human breast cancer cells: PPARγ binds to VDR and inhibits 1α,25-dihydroxyvitamin D3 mediated transactivation.	PPARG VDR	3.13e-06	2	62	2	22884583
Pubmed	Identification of the functional vitamin D response elements in the human MDR1 gene.	ABCB1 VDR	3.13e-06	2	62	2	18602086
Pubmed	[PPARγ signal transduction pathway in the foam cell formation induced by visfatin].	PPARG ABCB1	9.37e-06	3	62	2	20945045
Pubmed	Peroxisome proliferator-activated receptor γ B cell-specific-deficient mice have an impaired antibody response.	CD19 PPARG	9.37e-06	3	62	2	23041568
Pubmed	Stem-like tumor cells confer drug resistant properties to mantle cell lymphoma.	CD19 ABCB1	9.37e-06	3	62	2	21599592
Pubmed	Individual single tube genotyping and DNA pooling by allele-specific PCR to uncover associations of polymorphisms with complex diseases.	PPARG VDR	9.37e-06	3	62	2	16999948
Pubmed	Combined effect of MPO, GSTM1 and GSTT1 polymorphisms on chromosome aberrations and lung cancer risk.	MPO GSTT1	9.37e-06	3	62	2	14626895
Pubmed	Control of Circulating IgE by the Vitamin D Receptor In Vivo Involves B Cell Intrinsic and Extrinsic Mechanisms.	CD19 VDR	9.37e-06	3	62	2	28003380
Pubmed	Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism.	MPO PPARG	9.37e-06	3	62	2	14668325
Pubmed	Genetic Polymorphisms of Multidrug Resistance Gene-1 (MDR1/ABCB1) and Glutathione S-Transferase Gene and the Risk of Inflammatory Bowel Disease among Moroccan Patients.	GSTT1 ABCB1	9.37e-06	3	62	2	26604430
Pubmed	Association of the polymorphisms of MTHFR C677T, VDR C352T, and MPO G463A with risk for esophageal squamous cell dysplasia and carcinoma.	MPO VDR	9.37e-06	3	62	2	18662591
Pubmed	Absence of vitamin D receptor (VDR)-mediated PPARγ suppression causes alopecia in VDR-null mice.	PPARG VDR	9.37e-06	3	62	2	27932380
Pubmed	RNF2 interacts with the linker region of the human P-glycoprotein.	RNF2 ABCB1	9.37e-06	3	62	2	17088979
Pubmed	Genetic variations in radiation and chemotherapy drug action pathways and survival in locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy.	MPO ABCB1	1.87e-05	4	62	2	24340057
Pubmed	Vitamin D analog EB1089 inhibits aromatase expression by dissociation of comodulator WSTF from the CYP19A1 promoter-a new regulatory pathway for aromatase.	BAZ1B VDR	1.87e-05	4	62	2	23085504
Pubmed	Polymorphisms of glutathione S-transferase μ and θ, MDR1 and VEGF genes as risk factors of bladder cancer: a case-control study.	GSTT1 ABCB1	1.87e-05	4	62	2	21292509
Pubmed	Gene single nucleotide polymorphism accumulation improves survival in advanced head and neck cancer patients treated with weekly paclitaxel.	GSTT1 ABCB1	1.87e-05	4	62	2	19504558
Pubmed	Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion.	CD19 SIRT7	1.87e-05	4	62	2	35659337
Pubmed	Adipose-tissue Treg cells restrain differentiation of stromal adipocyte precursors to promote insulin sensitivity and metabolic homeostasis.	OSMR PPARG	1.87e-05	4	62	2	38692280
Pubmed	PPAR-γ, RXR, VDR, and COX-2 Expressions in gingival tissue samples of healthy individuals, periodontitis and peri-implantitis patients.	PPARG VDR	1.87e-05	4	62	2	31929206
Pubmed	Prognostic significance of the null genotype of glutathione S-transferase-T1 in patients with acute myeloid leukemia: increased early death after chemotherapy.	MPO GSTT1	1.87e-05	4	62	2	11840286
Pubmed	Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NF kappa B signalling.	PPARG VDR	1.87e-05	4	62	2	17521736
Pubmed	Analysis of hydroquinone and catechol in peripheral blood of benzene-exposed workers.	MPO GSTT1	1.87e-05	4	62	2	20026093
Pubmed	The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.	GSTT1 PPARG VDR	2.58e-05	32	62	3	20437058
Pubmed	Genetic polymorphisms involved in toxicant-metabolizing enzymes and the risk of chronic benzene poisoning in Chinese occupationally exposed populations.	MPO GSTT1	3.12e-05	5	62	2	17178637
Pubmed	CYP2E1 polymorphism, cigarette smoking, p53 expression, and survival in non-small cell lung cancer: a long term follow-up study.	MPO GSTT1	3.12e-05	5	62	2	15536330
Pubmed	Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia.	ABCB1 VDR	3.12e-05	5	62	2	12969965
Pubmed	Polymorphic metabolizing genes and susceptibility to atherosclerosis among cigarette smokers.	MPO GSTT1	3.12e-05	5	62	2	12355548
Pubmed	Glutathione-S-transferase-P1 I105V polymorphism and response to antenatal betamethasone in the prevention of respiratory distress syndrome.	GSTT1 ABCB1	3.12e-05	5	62	2	19183974
Pubmed	ABCB1 and GST polymorphisms associated with TP53 status in breast cancer.	GSTT1 ABCB1	3.12e-05	5	62	2	17301692
Pubmed	Genetic polymorphism of toxicant-metabolizing enzymes and prognosis of Chinese workers with chronic benzene poisoning.	MPO GSTT1	3.12e-05	5	62	2	17119198
Pubmed	Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer.	PPARG VDR	3.12e-05	5	62	2	32603375
Pubmed	Oxidative stress-related gene polymorphism and the risk of preeclampsia.	MPO GSTT1	3.12e-05	5	62	2	15734083
Pubmed	CYP1A1 Ile462Val and MPO G-463A interact to increase risk of adenocarcinoma but not squamous cell carcinoma of the lung.	MPO GSTT1	3.12e-05	5	62	2	16195240
Pubmed	Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.	MPO GSTT1	3.12e-05	5	62	2	12460800
Pubmed	Vitamin D Is Required for ILC3 Derived IL-22 and Protection From Citrobacter rodentium Infection.	CD19 VDR	3.12e-05	5	62	2	30723466
Pubmed	Genetic susceptibility to benzene toxicity in humans.	MPO GSTT1	3.12e-05	5	62	2	18836923
Pubmed	Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.	GSTT1 PPARG VDR	3.39e-05	35	62	3	18992148
Pubmed	Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.	GSTT1 PPARG ABCB1 VDR	4.27e-05	108	62	4	19956635
Pubmed	Influence of genetic polymorphisms in CYP3A4, CYP3A5, GSTP1, GSTM1, GSTT1 and MDR1 genes on survival and therapy-related toxicity in multiple myeloma.	GSTT1 ABCB1	4.67e-05	6	62	2	17296590
Pubmed	Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response.	GSTT1 ABCB1	4.67e-05	6	62	2	19621425
Pubmed	Combined effects of genetic polymorphisms in six selected genes on lung cancer susceptibility.	MPO GSTT1	4.67e-05	6	62	2	17428572
Pubmed	Analyses of bulky DNA adduct levels in human breast tissue and genetic polymorphisms of cytochromes P450 (CYPs), myeloperoxidase (MPO), quinone oxidoreductase (NQO1), and glutathione S-transferases (GSTs).	MPO GSTT1	4.67e-05	6	62	2	11943609
Pubmed	Exposure to low environmental levels of benzene: evaluation of micronucleus frequencies and S-phenylmercapturic acid excretion in relation to polymorphisms in genes encoding metabolic enzymes.	MPO GSTT1	4.67e-05	6	62	2	20951227
Pubmed	PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States).	PPARG VDR	4.67e-05	6	62	2	16489531
Pubmed	Gene-gene interactions of drug metabolizing enzymes and transporter protein in the risk of upper aerodigestive tract cancers among Indians.	GSTT1 ABCB1	4.67e-05	6	62	2	20554493
Pubmed	Association analysis of TNFR2, VDR, A2M, GSTT1, GSTM1, and ACE genes with rheumatoid arthritis in South Asians and Caucasians of East Midlands in the United Kingdom.	GSTT1 VDR	4.67e-05	6	62	2	20401725
Pubmed	Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer.	MPO GSTT1	4.67e-05	6	62	2	20091863
Pubmed	Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.	MPO PPARG ABCB1	5.48e-05	41	62	3	19878569
Pubmed	Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings.	PPARG VDR	6.53e-05	7	62	2	21478865
Pubmed	Genetic polymorphisms in the Hmong population: implications for cancer etiology and survival.	MPO GSTT1	6.53e-05	7	62	2	14716779
Pubmed	Genetic polymorphisms affecting clinical outcomes in epithelial ovarian cancer patients treated with taxanes and platinum compounds: a Korean population-based study.	GSTT1 ABCB1	6.53e-05	7	62	2	19203783
Pubmed	Pharmacokinetics and toxicity of docetaxel: role of CYP3A, MDR1, and GST polymorphisms.	GSTT1 ABCB1	6.53e-05	7	62	2	16765145
Pubmed	Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer.	MPO GSTT1	6.53e-05	7	62	2	15199549
Pubmed	Genetic polymorphisms and benzene metabolism in humans exposed to a wide range of air concentrations.	MPO GSTT1	6.53e-05	7	62	2	17885617
Pubmed	CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis.	MPO GSTT1	6.53e-05	7	62	2	15714076
Pubmed	Polymorphisms in genes involved in xenobiotic metabolism and lung cancer risk under the age of 60 years. A pooled study of lung cancer patients in Denmark and Norway.	MPO GSTT1	8.69e-05	8	62	2	15829318
Pubmed	PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation.	MPO CSF3R	8.69e-05	8	62	2	8777716
Pubmed	Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: results from the Malaysia-Singapore ALL Study Group.	GSTT1 ABCB1	8.69e-05	8	62	2	19651439
Pubmed	Effect of combined genetic polymorphisms on lung cancer risk in northern Thai women.	MPO GSTT1	8.69e-05	8	62	2	19963114
Pubmed	Analysis of polymorphic patterns in candidate genes in Israeli patients with prostate cancer.	GSTT1 VDR	8.69e-05	8	62	2	14719475
Pubmed	Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors.	PPARG VDR	8.69e-05	8	62	2	9121466
Pubmed	Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.	MPO GSTT1	8.69e-05	8	62	2	18642288
Pubmed	Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.	PPARG ABCB1 VDR	9.37e-05	49	62	3	18936436
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	GABRB1 DCHS2 ILF3 RNF2 PRSS55 ODAD2 OSMR CCDC33	9.64e-05	814	62	8	23251661
Pubmed	[Analysis of genetic predisposition to pulmonary tuberculosis in native Russians].	GSTT1 ABCB1	1.12e-04	9	62	2	20297661
Pubmed	Cigarette smoking and glutathione S-transferase M1 polymorphism associated with risk for uterine cervical cancer.	MPO GSTT1	1.12e-04	9	62	2	19012698
Pubmed	Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators.	PPARG VDR	1.12e-04	9	62	2	15888456
Pubmed	Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors.	PPARG VDR	1.12e-04	9	62	2	11891224
Pubmed	The GSTP1 Ile105 Val polymorphism modifies the metabolism of toluene di-isocyanate.	MPO GSTT1	1.39e-04	10	62	2	20032816
Pubmed	The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion.	PPARG VDR	1.39e-04	10	62	2	9653119
Pubmed	Comprehensive assessment of candidate genes and serological markers for the detection of prostate cancer.	GSTT1 VDR	1.39e-04	10	62	2	14693733
Pubmed	Polymorphisms in oxidative stress genes and risk for non-Hodgkin lymphoma.	MPO PPARG	1.39e-04	10	62	2	16543247
Pubmed	A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group.	ABCB1 VDR	1.70e-04	11	62	2	18285546
Pubmed	Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study.	MPO GSTT1	1.70e-04	11	62	2	18447907
Pubmed	Genetic background of lead and mercury metabolism in a group of medical students in Austria.	GSTT1 VDR	1.70e-04	11	62	2	19515364
Pubmed	Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia.	GSTT1 ABCB1	1.70e-04	11	62	2	16507781
Pubmed	BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin.	GSTT1 ABCB1	1.70e-04	11	62	2	20331623
Pubmed	Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.	ILF3 HUNK ABCB1	1.72e-04	60	62	3	22889411
Pubmed	Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.	PPARG ABCB1 VDR	1.89e-04	62	62	3	20403997
Pubmed	Candidate gene polymorphisms for ischemic stroke.	MPO PPARG VDR	2.08e-04	64	62	3	19729601
Pubmed	Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.	GSTT1 ABCB1	2.41e-04	13	62	2	16771603
Pubmed	Replication of recently described type 2 diabetes gene variants in a South Indian population.	BAZ1B PPARG	2.41e-04	13	62	2	20580033
Pubmed	Pharmacogenomic variations in treatment protocols for childhood acute lymphoblastic leukemia.	GSTT1 ABCB1	2.41e-04	13	62	2	19774638
Pubmed	Toward personalized medicine in renal transplantation.	GSTT1 ABCB1	2.81e-04	14	62	2	20970553
Pubmed	Pharmacogenetic analyses of hematotoxicity in advanced gastric cancer patients receiving biweekly fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT): a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).	GSTT1 ABCB1	3.23e-04	15	62	2	19074750
Pubmed	Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy.	MPO ABCB1	3.23e-04	15	62	2	18854777
Pubmed	Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes, DNA repair enzymes, and response to treatment of childhood acute lymphoblastic leukemia.	MPO GSTT1	3.23e-04	15	62	2	11895912
Pubmed	A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer.	MPO GSTT1 PPARG	3.32e-04	75	62	3	20644561
Cytoband	8q22	RNF19A MYBL1	1.86e-04	15	62	2	8q22
Cytoband	17p13.3	SLC43A2 WDR81 VPS53	2.37e-04	88	62	3	17p13.3
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GARIN5B IMPDH1 CD19 ENPEP CCDC33	4.67e-06	176	62	5	29cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GARIN5B IMPDH1 CD19 ENPEP CCDC33	4.67e-06	176	62	5	01774a86d7d92f31a056b753f9844f923038003e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GREB1L FRY HUNK PPARG ABCB1	6.28e-06	187	62	5	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAM171A2 MUC16 HUNK ALDH3B2 CCDC33	7.50e-06	194	62	5	e0228f593c3493175962a4817500d4337ddc4e88
Disease	cardiovascular system disease (is_implicated_in)	MPO GSTT1 PPARG	1.04e-05	21	60	3	DOID:1287 (is_implicated_in)
Disease	end stage renal disease (is_implicated_in)	MPO GSTT1 PPARG	8.06e-05	41	60	3	DOID:783 (is_implicated_in)
Disease	pulmonary tuberculosis (is_implicated_in)	GSTT1 ABCB1 VDR	8.67e-05	42	60	3	DOID:2957 (is_implicated_in)
Disease	liver cirrhosis (is_implicated_in)	MPO GSTT1 VDR	9.31e-05	43	60	3	DOID:5082 (is_implicated_in)
Disease	glucose metabolism decline measurement, cingulate cortex measurement	TBC1D8 VPS53	1.45e-04	9	60	2	EFO_0007738, EFO_0009392
Disease	bronchopulmonary dysplasia (is_implicated_in)	GSTT1 VDR	3.13e-04	13	60	2	DOID:11650 (is_implicated_in)
Disease	skin melanoma (is_implicated_in)	GSTT1 VDR	3.64e-04	14	60	2	DOID:8923 (is_implicated_in)
Disease	Benign Neoplasm	GSTT1 ABCB1 VDR	3.65e-04	68	60	3	C0086692
Disease	Neoplasms	GSTT1 ABCB1 VDR	3.65e-04	68	60	3	C0027651
Disease	hepatic encephalopathy (biomarker_via_orthology)	GABRB1 ABCB1	4.20e-04	15	60	2	DOID:13413 (biomarker_via_orthology)
Disease	hepatocellular carcinoma (is_implicated_in)	MPO GSTT1 ABCB1 VDR	5.11e-04	181	60	4	DOID:684 (is_implicated_in)
Disease	heel bone mineral density, urate measurement	GABRB1 TBC1D8 THEMIS SON	5.22e-04	182	60	4	EFO_0004531, EFO_0009270
Disease	ulcerative colitis (is_implicated_in)	GSTT1 ABCB1	5.42e-04	17	60	2	DOID:8577 (is_implicated_in)
Disease	retinal vasculature measurement	GABRB1 FRY MYPN MYOZ2 NAV3 OSMR	6.32e-04	517	60	6	EFO_0010554
Disease	Lipoidosis	DEPP1 PPARG	6.80e-04	19	60	2	C0023794
Disease	Pseudopelade	PPARG VDR	6.80e-04	19	60	2	C0086873
Disease	Reperfusion Injury	MPO SIRT7 PPARG	8.02e-04	89	60	3	C0035126
Disease	esophagus adenocarcinoma (is_implicated_in)	GSTT1 VDR	8.33e-04	21	60	2	DOID:4914 (is_implicated_in)
Disease	lung disease (is_implicated_in)	MPO GSTT1	9.15e-04	22	60	2	DOID:850 (is_implicated_in)
Disease	serum albumin measurement	SLC43A2 FRY WDR81 PPARG PKD1L3 NSUN7	1.27e-03	592	60	6	EFO_0004535
Disease	atopic dermatitis (is_implicated_in)	GSTT1 VDR	1.28e-03	26	60	2	DOID:3310 (is_implicated_in)
Disease	cystic fibrosis (is_implicated_in)	MPO GSTT1	1.38e-03	27	60	2	DOID:1485 (is_implicated_in)
Disease	acute kidney failure (implicated_via_orthology)	MPO PPARG	1.38e-03	27	60	2	DOID:3021 (implicated_via_orthology)
Disease	myelodysplastic syndrome (is_implicated_in)	GSTT1 CSF3R	1.71e-03	30	60	2	DOID:0050908 (is_implicated_in)
Disease	Crohn's disease (is_implicated_in)	GSTT1 ABCB1	1.71e-03	30	60	2	DOID:8778 (is_implicated_in)
Disease	Alcoholic Intoxication	MPO CD19	1.94e-03	32	60	2	C0001969

Protein segments in the cluster

Peptide	Gene	Start	Entry
SVTLELSQLSMLPHL	VDR	216	P11473
LHVERLPIMDTSLKT	CCDC33	536	Q8N5R6
HLPTIRETTEEMLLG	DEPP1	11	Q9NTK1
MKLSEIPLTLHSVSE	BAZ1B	676	Q9UIG0
IHEMFLSTLDPKTIS	ACOT9	261	Q9Y305
LSISDPIHMVLIKTD	CEP76	186	Q8TAP6
MTAATKHLTPVTLEL	ALDH3B2	116	P48448
VTTPDEHSSMLIHIL	OSMR	731	Q99650
AHIIMIIEKTPLIDS	ABCB1	1006	P08183
LEDVMTLLSLSHAPL	RELCH	931	Q9P260
AETMDIPSTHIAKTL	MUC16	371	Q8WXI7
MHSVFSPILLLSLVT	SLC43A2	316	Q8N370
IIILTTLDVHLQTPM	OR14L1P	46	Q8NHC6
SSEMPELTSMHTLLL	MPO	406	P05164
MTSLHTSSESIDLPL	NAV3	1366	Q8IVL0
STIPLILSASDMLHS	CES5A	541	Q6NT32
MTTISTHLRETLPKI	GABRB1	286	P18505
EMSDIVLLITDIRHP	GNL1	186	P36915
DDSLMSSHPIIVTVT	ENPEP	451	Q07075
LILVTILDSRLHTPM	OR2S2	46	Q9NQN1
HSTPETLSIMDDLIS	GREB1L	931	Q9C091
HTTLLSEVMTPRIEL	IMPDH1	171	P20839
TLPLSHLESTTLSLM	DCHS2	831	Q6V1P9
ELMPLTAVSVHLLTG	FAM171A2	206	A8MVW0
MVRTELIESVHSPVT	MAP3K13	51	O43283
ATALLTTIEEMHLLS	COG6	396	Q9Y2V7
LSTMTTEPVLESLDI	ATMIN	656	O43313
LLEIVTSVLLHPSMA	HEATR5B	446	Q9P2D3
LTMSFHLEITARPVL	CD19	266	P15391
SLTIHLTSPVVREEM	ILF3	166	Q12906
EDLSPSVVLHMTEKL	HUNK	341	P57058
SFSILMSPHILESLI	ADGRF2	431	Q8IZF7
LMTLTPEGSELHIIL	CSF3R	616	Q99062
HTTLVETLSLPMLAA	KANSL3	196	Q9P2N6
SQILEHSDLIMTLSP	FRY	2531	Q5TBA9
IIESVVSPIMELSHA	CCDC168	1246	Q8NDH2
LLTTPMLTVLHETFS	MFSD14C	61	Q5VZR4
LLTTPMLTVLHETFS	MFSD14B	61	Q5SR56
TTSLLMIPLLEIHDN	MYBL1	656	P10243
LEIVVSPRSLHSELM	RNF2	36	Q99496
MPRTLSLHEITDLLE	PGBD3	1	Q8N328
PHISLADLVAITELM	GSTT1	161	P30711
SSPILELHSEDTLQM	LCMT1	141	Q9UIC8
SLLPSVHTIILDFSM	SLC26A8	716	Q96RN1
STTIPDHLSSLIIVM	NSUN7	116	Q8NE18
SLKHISLEISLSPMT	ODAD2	186	Q5T2S8
KTETDMSLHPLLQEI	PPARG	486	P37231
MVLIPTDELHERLTS	PKD1L3	1416	Q7Z443
LLELLMTEILHPSSQ	RRP1	146	P56182
SEAEPTLTHMSITRL	SIRT7	141	Q9NRC8
LIMLPDHVSIILLSA	SKIV2L	441	Q15477
VSRSAHTPSDIELML	STARD9	4326	Q9P2P6
TMTIISVTLEIPHHI	AGAP5	161	A6NIR3
TTISIPLLLVHDMSE	C12orf4	466	Q9NQ89
ILMSVEEKIPHLTIS	NLRP9	961	Q7RTR0
LTMEEITRTIHIGPS	THEMIS	96	Q8N1K5
AESLLSEPMVHELVL	RWDD3	91	Q9Y3V2
DPVSILTSILDMSLH	RNF19A	21	Q9NV58
VVSIEKMEDTSLLPH	TBC1D8	346	O95759
HSLKMVLLDLPSISS	VPS53	701	Q5VIR6
SPSMEIKEVASIILH	PRSS55	131	Q6UWB4
HRSPLKLSSTLITEM	nan	141	Q96MT0
SVTHSPEIMDLSELR	TOGARAM1	1236	Q9Y4F4
VVSMEVSEPHILETL	SON	191	P18583
LSDTTLMDILPRISH	WDR81	1356	Q562E7
SSSEILLPMLLELET	GARIN5B	871	Q8N5Q1
VSIPRDIMLEELSHL	MYOZ2	36	Q9NPC6
MLVRETGVHSLLIDP	MYPN	1121	Q86TC9