Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of ARF protein signal transduction	CYTH3 CYTH2 CYTH4	2.74e-06	23	25	3	GO:0032012
GeneOntologyBiologicalProcess	ARF protein signal transduction	CYTH3 CYTH2 CYTH4	3.13e-06	24	25	3	GO:0032011
GeneOntologyBiologicalProcess	regulation of cellular response to insulin stimulus	C1QTNF9B GRB14 INPPL1 C1QTNF9	6.33e-06	101	25	4	GO:1900076
GeneOntologyBiologicalProcess	negative regulation of cell size	C1QTNF9B C1QTNF9	1.47e-04	15	25	2	GO:0045792
GeneOntologyBiologicalProcess	cellular response to insulin stimulus	C1QTNF9B GRB14 INPPL1 C1QTNF9	2.97e-04	271	25	4	GO:0032869
Domain	Sec7	CYTH3 CYTH2 CYTH4	6.40e-07	15	22	3	PF01369
Domain	Sec7_alpha_orthog	CYTH3 CYTH2 CYTH4	6.40e-07	15	22	3	IPR023394
Domain	-	CYTH3 CYTH2 CYTH4	6.40e-07	15	22	3	1.10.1000.11
Domain	Sec7	CYTH3 CYTH2 CYTH4	7.86e-07	16	22	3	SM00222
Domain	Sec7_dom	CYTH3 CYTH2 CYTH4	7.86e-07	16	22	3	IPR000904
Domain	SEC7	CYTH3 CYTH2 CYTH4	7.86e-07	16	22	3	PS50190
Domain	PH	GRB14 CYTH3 CYTH2 PLEKHH3 CYTH4	1.51e-05	278	22	5	SM00233
Domain	PH_DOMAIN	GRB14 CYTH3 CYTH2 PLEKHH3 CYTH4	1.53e-05	279	22	5	PS50003
Domain	PH_domain	GRB14 CYTH3 CYTH2 PLEKHH3 CYTH4	1.56e-05	280	22	5	IPR001849
Domain	HELP	EML5 EML4	1.98e-05	6	22	2	PF03451
Domain	HELP	EML5 EML4	1.98e-05	6	22	2	IPR005108
Domain	-	GRB14 CYTH3 CYTH2 PLEKHH3 CYTH4	7.69e-05	391	22	5	2.30.29.30
Domain	PH_dom-like	GRB14 CYTH3 CYTH2 PLEKHH3 CYTH4	1.15e-04	426	22	5	IPR011993
Domain	PH	GRB14 CYTH3 CYTH2 CYTH4	1.35e-04	229	22	4	PF00169
Domain	C1Q	C1QTNF9B C1QTNF9	6.43e-04	32	22	2	SM00110
Domain	C1q	C1QTNF9B C1QTNF9	6.43e-04	32	22	2	PF00386
Domain	C1q_dom	C1QTNF9B C1QTNF9	7.26e-04	34	22	2	IPR001073
Domain	C1Q	C1QTNF9B C1QTNF9	7.26e-04	34	22	2	PS50871
Domain	RA	GRB14 PLEKHH3	8.14e-04	36	22	2	PF00788
Domain	WD40_repeat_CS	EML5 EML4 WDFY1	9.05e-04	164	22	3	IPR019775
Domain	RA_dom	GRB14 PLEKHH3	1.01e-03	40	22	2	IPR000159
Domain	ABC_transporter_CS	ABCA2 ABCB10	1.11e-03	42	22	2	IPR017871
Domain	ABC_TRANSPORTER_2	ABCA2 ABCB10	1.45e-03	48	22	2	PS50893
Domain	ABC_tran	ABCA2 ABCB10	1.45e-03	48	22	2	PF00005
Domain	ABC_TRANSPORTER_1	ABCA2 ABCB10	1.51e-03	49	22	2	PS00211
Domain	-	C1QTNF9B C1QTNF9	1.57e-03	50	22	2	2.60.120.40
Domain	ABC_transporter-like	ABCA2 ABCB10	1.57e-03	50	22	2	IPR003439
Domain	Quinoprotein_ADH-like_supfam	EML5 EML4	1.76e-03	53	22	2	IPR011047
Domain	Tumour_necrosis_fac-like_dom	C1QTNF9B C1QTNF9	2.10e-03	58	22	2	IPR008983
Domain	WD40	EML5 EML4 WDFY1	3.34e-03	259	22	3	PF00400
Domain	WD40	EML5 EML4 WDFY1	3.68e-03	268	22	3	SM00320
Domain	WD40_repeat	EML5 EML4 WDFY1	3.83e-03	272	22	3	IPR001680
Domain	WD_REPEATS_1	EML5 EML4 WDFY1	4.07e-03	278	22	3	PS00678
Domain	WD_REPEATS_2	EML5 EML4 WDFY1	4.12e-03	279	22	3	PS50082
Domain	WD_REPEATS_REGION	EML5 EML4 WDFY1	4.12e-03	279	22	3	PS50294
Domain	Collagen	C1QTNF9B C1QTNF9	4.46e-03	85	22	2	PF01391
Domain	Collagen	C1QTNF9B C1QTNF9	4.46e-03	85	22	2	IPR008160
Domain	WD40_repeat_dom	EML5 EML4 WDFY1	4.90e-03	297	22	3	IPR017986
Domain	SH2	GRB14 INPPL1	6.23e-03	101	22	2	PF00017
Domain	-	EML5 EML4 WDFY1	6.73e-03	333	22	3	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	EML5 EML4 WDFY1	6.84e-03	335	22	3	IPR015943
Domain	SH2	GRB14 INPPL1	7.35e-03	110	22	2	SM00252
Domain	SH2	GRB14 INPPL1	7.48e-03	111	22	2	PS50001
Domain	SH2	GRB14 INPPL1	7.61e-03	112	22	2	IPR000980
Domain	-	GRB14 INPPL1	7.61e-03	112	22	2	3.30.505.10
Domain	S_TKc	TTBK2 CDK13 MAP3K2	8.27e-03	359	22	3	SM00220
Domain	PROTEIN_KINASE_ST	TTBK2 CDK13 MAP3K2	8.46e-03	362	22	3	PS00108
Domain	Protein_kinase_ATP_BS	TTBK2 CDK13 MAP3K2	9.59e-03	379	22	3	IPR017441
Domain	Pkinase	TTBK2 CDK13 MAP3K2	9.73e-03	381	22	3	PF00069
Domain	AAA+_ATPase	ABCA2 ABCB10	1.23e-02	144	22	2	IPR003593
Domain	AAA	ABCA2 ABCB10	1.23e-02	144	22	2	SM00382
Domain	PROTEIN_KINASE_ATP	TTBK2 CDK13 MAP3K2	1.60e-02	459	22	3	PS00107
Pathway	BIOCARTA_ARAP_PATHWAY	CYTH3 CYTH2 CYTH4	9.80e-07	17	17	3	M2482
Pathway	KEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY	CYTH3 CYTH2 CYTH4	3.30e-06	25	17	3	M47716
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY	CYTH3 CYTH2 CYTH4	5.22e-06	29	17	3	M47717
Pathway	KEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY	CYTH3 CYTH2 CYTH4	5.80e-06	30	17	3	M47738
Pathway	REACTOME_INTRA_GOLGI_TRAFFIC	CYTH3 CYTH2 CYTH4	1.10e-05	37	17	3	MM15354
Pathway	REACTOME_INTRA_GOLGI_TRAFFIC	CYTH3 CYTH2 CYTH4	1.87e-05	44	17	3	M27652
Pathway	PID_PI3KCI_PATHWAY	CYTH3 CYTH2 INPPL1	2.44e-05	48	17	3	M141
Pathway	WP_INSULIN_SIGNALING	GRB14 CYTH3 INPPL1 MAP3K2	3.39e-05	160	17	4	M39482
Pathway	WP_INSULIN_SIGNALING	GRB14 CYTH3 INPPL1 MAP3K2	3.39e-05	160	17	4	MM15956
Pathway	BIOCARTA_ARAP_PATHWAY	CYTH3 CYTH2	8.97e-05	12	17	2	MM1342
Pathway	WP_2Q37_COPY_NUMBER_VARIATION_SYNDROME	CYTH3 CYTH2 CYTH4	6.52e-04	145	17	3	M45512
Pathway	WP_13Q1212_COPY_NUMBER_VARIATION	C1QTNF9B C1QTNF9	7.51e-04	34	17	2	M48103
Pathway	PID_ARF6_PATHWAY	CYTH3 CYTH2	7.96e-04	35	17	2	M86
Pathway	KEGG_ABC_TRANSPORTERS	ABCA2 ABCB10	1.26e-03	44	17	2	M11911
Pathway	WP_EGFR1_SIGNALING_PATHWAY	GRB14 INPPL1 MAP3K2	1.38e-03	188	17	3	MM15828
Pathway	REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC	CYTH3 CYTH2 CYTH4	1.40e-03	189	17	3	MM15356
Pathway	SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES	CYTH3 INPPL1	1.69e-03	51	17	2	M7955
Pathway	REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC	CYTH3 CYTH2 CYTH4	1.72e-03	203	17	3	M27654
Pathway	SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES	CYTH3 INPPL1	2.89e-03	67	17	2	M295
Pubmed	Similarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factors.	CYTH3 CYTH2 CYTH4	1.31e-09	4	25	3	10652308
Pubmed	Interaction protein for cytohesin exchange factors 1 (IPCEF1) binds cytohesin 2 and modifies its activity.	CYTH3 CYTH2 CYTH4	3.28e-09	5	25	3	12920129
Pubmed	The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.	CYTH3 CYTH2 CYTH4	1.83e-08	8	25	3	17398095
Pubmed	A crucial role for Arf6 in the response of commissural axons to Slit.	CYTH3 CYTH2 CYTH4	3.15e-07	19	25	3	30674481
Pubmed	Targeted deletion of C1q/TNF-related protein 9 increases food intake, decreases insulin sensitivity, and promotes hepatic steatosis in mice.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	24473438
Pubmed	C1q/TNF-Related Protein 9 (CTRP9) attenuates hepatic steatosis via the autophagy-mediated inhibition of endoplasmic reticulum stress.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	26419929
Pubmed	CTRP9 induces iNOS expression through JAK2/STAT3 pathway in Raw 264.7 and peritoneal macrophages.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	31837806
Pubmed	Adipose-derived factor CTRP9 attenuates vascular smooth muscle cell proliferation and neointimal formation.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	22972916
Pubmed	C1q/TNF-related proteins, a family of novel adipokines, induce vascular relaxation through the adiponectin receptor-1/AMPK/eNOS/nitric oxide signaling pathway.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	21836066
Pubmed	Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion.	ABCA2 ABCB10	4.96e-07	2	25	2	21788586
Pubmed	Autoantibodies Against β1-Adrenoceptor Exaggerated Ventricular Remodeling by Inhibiting CTRP9 Expression.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	30764693
Pubmed	CTRP9 Promotes Brown Adipose Tissue Lipolysis in Mice Fed a High-Fat Diet.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	38940054
Pubmed	C1q/Tumor Necrosis Factor-Related Protein-9 Regulates the Fate of Implanted Mesenchymal Stem Cells and Mobilizes Their Protective Effects Against Ischemic Heart Injury via Multiple Novel Signaling Pathways.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	28978553
Pubmed	C1q/tumor necrosis factor-related protein-9, a novel adipocyte-derived cytokine, attenuates adverse remodeling in the ischemic mouse heart via protein kinase A activation.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	24030394
Pubmed	CTRP9 alleviates foam cells apoptosis by enhancing cholesterol efflux.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	33352225
Pubmed	Ablation of Ctrp9, Ligand of AdipoR1, and Lower Number of Cone Photoreceptors in Mouse Retina.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	35575905
Pubmed	Overexpression of CTRP9 attenuates the development of atherosclerosis in apolipoprotein E-deficient mice.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	30426302
Pubmed	Globular CTRP9 inhibits oxLDL-induced inflammatory response in RAW 264.7 macrophages via AMPK activation.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	27188183
Pubmed	Association of C1q/TNF-Related Protein-9 (CTRP9) Level with Obstructive Sleep Apnea in Patients with Coronary Artery Disease.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	32831639
Pubmed	C1q-TNF-Related Protein-9 Promotes Cardiac Hypertrophy and Failure.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	27821723
Pubmed	CTRP9 ameliorates cellular senescence via PGC‑1α/AMPK signaling in mesenchymal stem cells.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	29749459
Pubmed	C1q and Tumor Necrosis Factor Related Protein 9 Protects from Diabetic Cardiomyopathy by Alleviating Cardiac Insulin Resistance and Inflammation.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	36766785
Pubmed	CTRP9 Regulates Growth, Differentiation, and Apoptosis in Human Keratinocytes through TGFβ1-p38-Dependent Pathway.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	29145717
Pubmed	Reduction of CTRP9, a novel anti-platelet adipokine, contributes to abnormal platelet activity in diabetic animals.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	26754066
Pubmed	Hypermethylation of the CTRP9 promoter region promotes Hcy induced VSMC lipid deposition and foam cell formation via negatively regulating ER stress.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	37945738
Pubmed	C1q/tumour necrosis factor-related protein-9 aggravates lipopolysaccharide-induced inflammation via promoting NLRP3 inflammasome activation.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	35008006
Pubmed	CTRP 9 mitigates the apoptosis and unfolded protein response of OGD/R-induced retinal ganglion cells by regulating the AMPK pathway.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	38741428
Pubmed	C1q/Tumor Necrosis Factor-Related Protein-9 Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	32283037
Pubmed	CTRP9 protein protects against myocardial injury following ischemia-reperfusion through AMP-activated protein kinase (AMPK)-dependent mechanism.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	22514273
Pubmed	C1q-TNF-related protein-9, a novel cardioprotetcive cardiokine, requires proteolytic cleavage to generate a biologically active globular domain isoform.	C1QTNF9B C1QTNF9	4.96e-07	2	25	2	25783894
Pubmed	Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.	CYTH3 CYTH2	4.96e-07	2	25	2	31601460
Pubmed	C1q/TNF-related protein-9 attenuates retinal inflammation and protects blood-retinal barrier in db/db mice.	C1QTNF9B C1QTNF9	1.49e-06	3	25	2	30978318
Pubmed	CTRP9 knockout exaggerates lipotoxicity in cardiac myocytes and high-fat diet-induced cardiac hypertrophy through inhibiting the LKB1/AMPK pathway.	C1QTNF9B C1QTNF9	1.49e-06	3	25	2	31930700
Pubmed	Phosphoinositide specificity determines which cytohesins regulate β1 integrin recycling.	CYTH3 CYTH2	1.49e-06	3	25	2	22454518
Pubmed	Fecal microbiota transplantation ameliorates atherosclerosis in mice with C1q/TNF-related protein 9 genetic deficiency.	C1QTNF9B C1QTNF9	1.49e-06	3	25	2	35115674
Pubmed	C1q/Tumor Necrosis Factor-Related Protein 9 Protects against Acute Myocardial Injury through an Adiponectin Receptor I-AMPK-Dependent Mechanism.	C1QTNF9B C1QTNF9	1.49e-06	3	25	2	25870106
Pubmed	Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors.	CYTH3 CYTH2	1.49e-06	3	25	2	18042453
Pubmed	Complex regulation of multiple cytohesin-like genes in murine tissues and cells.	CYTH3 CYTH2	1.49e-06	3	25	2	9744817
Pubmed	Cardiac-derived CTRP9 protects against myocardial ischemia/reperfusion injury via calreticulin-dependent inhibition of apoptosis.	C1QTNF9B C1QTNF9	1.49e-06	3	25	2	29925877
Pubmed	CTRP9 transgenic mice are protected from diet-induced obesity and metabolic dysfunction.	C1QTNF9B C1QTNF9	1.49e-06	3	25	2	23842676
Pubmed	CTRP9 enhances carotid plaque stability by reducing pro-inflammatory cytokines in macrophages.	C1QTNF9B C1QTNF9	1.49e-06	3	25	2	25701788
Pubmed	Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin.	C1QTNF9B C1QTNF9	2.97e-06	4	25	2	18787108
Pubmed	CTRP8 and CTRP9B are novel proteins that hetero-oligomerize with C1q/TNF family members.	C1QTNF9B C1QTNF9	2.97e-06	4	25	2	19666007
Pubmed	BCL-6 promotes the methylation of miR-34a by recruiting EZH2 and upregulating CTRP9 to protect ischemic myocardial injury.	C1QTNF9B C1QTNF9	2.97e-06	4	25	2	33502806
Pubmed	C1q/Tumor Necrosis Factor-Related Protein-9 Is a Novel Vasculoprotective Cytokine That Restores High Glucose-Suppressed Endothelial Progenitor Cell Functions by Activating the Endothelial Nitric Oxide Synthase.	C1QTNF9B C1QTNF9	2.97e-06	4	25	2	38348774
Pubmed	Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration.	CYTH3 CYTH2	2.97e-06	4	25	2	12606567
Pubmed	CTRP9 induces mitochondrial biogenesis and protects high glucose-induced endothelial oxidative damage via AdipoR1 -SIRT1- PGC-1α activation.	C1QTNF9B C1QTNF9	4.95e-06	5	25	2	27349872
Pubmed	Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains.	CYTH3 CYTH2	4.95e-06	5	25	2	21041639
Pubmed	INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling.	CYTH3 CYTH2	7.43e-06	6	25	2	30355448
Pubmed	GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion.	CYTH3 CYTH4	1.04e-05	7	25	2	18084281
Pubmed	Characterization and mapping of three new mammalian ATP-binding transporter genes from an EST database.	ABCA2 ABCB10	1.04e-05	7	25	2	7766993
Pubmed	FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex.	CYTH3 CYTH2	1.39e-05	8	25	2	20080746
Pubmed	The N-terminal coiled-coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with Galphaq.	CYTH3 CYTH2	1.78e-05	9	25	2	17846866
Pubmed	Interaction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.	CYTH3 CYTH2	2.22e-05	10	25	2	10828067
Pubmed	Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions.	C1QTNF9B C1QTNF9	3.26e-05	12	25	2	18783346
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCA2 CDK13 CYTH3 INPPL1 PLEKHH3 CYTH4	1.07e-04	1105	25	6	35748872
Pubmed	Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.	TTBK2 CDK13 PLEKHH3	1.65e-04	149	25	3	22664934
Pubmed	C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.	CYTH3 CYTH2	1.72e-04	27	25	2	29420262
Pubmed	Analysis of mouse embryonic patterning and morphogenesis by forward genetics.	TTBK2 DDX11L8	2.58e-04	33	25	2	15755804
Interaction	IPCEF1 interactions	CYTH3 CYTH2 CYTH4	2.76e-07	11	25	3	int:IPCEF1
Interaction	CNKSR1 interactions	CYTH3 CYTH2 CYTH4	2.99e-05	49	25	3	int:CNKSR1
Cytoband	13q12.12	C1QTNF9B C1QTNF9	7.15e-05	23	25	2	13q12.12
Cytoband	11q13	INPPL1 CCS	1.89e-03	118	25	2	11q13
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	GRB14 CYTH3 CYTH2 PLEKHH3 CYTH4	1.39e-06	206	18	5	682
GeneFamily	Endogenous ligands\|C1q and TNF related	C1QTNF9B C1QTNF9	1.42e-04	18	18	2	1372
GeneFamily	WD repeat domain containing	EML5 EML4 WDFY1	2.09e-03	262	18	3	362
GeneFamily	SH2 domain containing	GRB14 INPPL1	4.46e-03	101	18	2	741
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CDCA3 GRB14 CLCNKB C1QTNF9	3.56e-06	189	25	4	c8b8f860aaf6c73863cd79941db6b469c830ef06
Drug	SecinH3	CYTH3 CYTH2 CYTH4	7.53e-08	9	23	3	CID001029232
Drug	AC1N9TEG	CYTH3 CYTH2 INPPL1 CYTH4	6.85e-06	124	23	4	CID000000478
Drug	glycylglycylglycine	CYTH3 CYTH2 CYTH4	8.68e-06	40	23	3	CID000011161
Disease	skin disease (implicated_via_orthology)	C1QTNF9B C1QTNF9	2.07e-06	3	25	2	DOID:37 (implicated_via_orthology)
Disease	hypertension (is_implicated_in)	CLCNKB INPPL1	4.70e-03	121	25	2	DOID:10763 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GERKGLVSRGLGRGW	FAM228A	176	Q86W67
MKGLGAGGRLWELLE	ABCB10	456	Q9NRK6
DREGWLLKLGGRVKT	CYTH4	261	Q9UIA0
GGGGLSWAEKKLEER	CDK13	11	Q14004
ILGTGRLLKTGGRAW	CDCA3	236	Q99618
WRLGKLLGQGAFGRV	MAP3K2	356	Q9Y2U5
GVRGIRGWKGDRGEK	C1QTNF9	176	P0C862
RGWKGDRGEKGKIGE	C1QTNF9	181	P0C862
EKPGRREKLLGWLRG	C6orf47	146	O95873
DREGWLLKLGGGRVK	CYTH2	261	Q99418
LLKLGGGRVKTWKRR	CYTH2	266	Q99418
WEKGGLLGRLAARKK	DDX11L8	721	A8MPP1
GVRGIRGWKGDRGEK	C1QTNF9B	176	B2RNN3
RGWKGDRGEKGKIGE	C1QTNF9B	181	B2RNN3
IWEERGRPIAGKGRK	CCS	251	O14618
DREGWLLKLGGGRVK	CYTH3	266	O43739
LLKLGGGRVKTWKRR	CYTH3	271	O43739
RVGQGSRKLDGGWLK	ABCA2	1421	Q9BZC7
WRELLDRGGKGLLLG	MDH1B	66	Q5I0G3
EEGLAWRKKGCLRLG	GRB14	401	Q14449
GGGKDRKIILWDHDL	EML4	526	Q9HC35
KFWRKAGGGLIGRKG	EML5	841	Q05BV3
KLARTGGVLGIKIGW	P2RX3	231	P56373
LGGWKRLRGMGRAEA	PLEKHH3	631	Q7Z736
VGDREWLDLLRGGLK	INPPL1	476	O15357
GIRGGLEWLKQKLFR	CLCNKB	31	P51801
WKVLRKIGGGGFGEI	TTBK2	21	Q6IQ55
WDIGGRKGRTLLLQG	WDFY1	226	Q8IWB7
GILRSWGRKGLSEKL	GEMIN4	501	P57678