Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	maintenance of postsynaptic density structure	SHANK1 CSMD2 PRICKLE2	1.57e-05	9	120	3	GO:0099562
MousePheno	increased circulating xanthine level	XDH MOCOS	4.47e-05	2	94	2	MP:0031490
MousePheno	abnormal circulating xanthine level	XDH MOCOS	4.47e-05	2	94	2	MP:0031488
MousePheno	increased circulating hypoxanthine level	XDH MOCOS	1.34e-04	3	94	2	MP:0031487
MousePheno	abnormal circulating hypoxanthine level	XDH MOCOS	1.34e-04	3	94	2	MP:0031485
MousePheno	increased urine hypoxanthine level	XDH MOCOS	1.34e-04	3	94	2	MP:0031484
MousePheno	abnormal urine hypoxanthine level	XDH MOCOS	1.34e-04	3	94	2	MP:0031482
Domain	WD40	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	7.25e-06	259	121	10	PF00400
Domain	WD40	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	9.78e-06	268	121	10	SM00320
Domain	-	SEMA4F TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	1.09e-05	333	121	11	2.130.10.10
Domain	WD40_repeat	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	1.11e-05	272	121	10	IPR001680
Domain	FG_GAP	ITGA8 CRTAC1 ITGA2B ITGA3	1.12e-05	22	121	4	PS51470
Domain	WD40_repeat_CS	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 HERC1 DCAF12	1.16e-05	164	121	8	IPR019775
Domain	WD40/YVTN_repeat-like_dom	SEMA4F TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	1.16e-05	335	121	11	IPR015943
Domain	WD_REPEATS_1	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	1.34e-05	278	121	10	PS00678
Domain	WD_REPEATS_2	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	1.39e-05	279	121	10	PS50082
Domain	WD_REPEATS_REGION	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	1.39e-05	279	121	10	PS50294
Domain	FG-GAP	ITGA8 CRTAC1 ITGA2B ITGA3	1.61e-05	24	121	4	PF01839
Domain	FG-GAP	ITGA8 CRTAC1 ITGA2B ITGA3	1.61e-05	24	121	4	IPR013517
Domain	Keratin_2_head	KRT6A KRT6B KRT75 KRT6C	1.61e-05	24	121	4	IPR032444
Domain	Keratin_2_head	KRT6A KRT6B KRT75 KRT6C	1.61e-05	24	121	4	PF16208
Domain	Keratin_II	KRT6A KRT6B KRT75 KRT6C	2.24e-05	26	121	4	IPR003054
Domain	WD40_repeat_dom	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	2.37e-05	297	121	10	IPR017986
Domain	Integrin_alpha_C_CS	ITGA8 ITGA2B ITGA3	1.40e-04	16	121	3	IPR018184
Domain	Pkinase	VRK2 CDK11A CIT PIM3 TRIB3 CSNK1D CSNK1E STK33 CDK11B PINK1	1.88e-04	381	121	10	PF00069
Domain	Integrin_alpha-2	ITGA8 ITGA2B ITGA3	2.02e-04	18	121	3	IPR013649
Domain	INTEGRIN_ALPHA	ITGA8 ITGA2B ITGA3	2.02e-04	18	121	3	PS00242
Domain	Integrin_alpha2	ITGA8 ITGA2B ITGA3	2.02e-04	18	121	3	PF08441
Domain	Integrin_alpha	ITGA8 ITGA2B ITGA3	2.02e-04	18	121	3	IPR000413
Domain	Int_alpha	ITGA8 ITGA2B ITGA3	2.38e-04	19	121	3	SM00191
Domain	Int_alpha_beta-p	ITGA8 ITGA2B ITGA3	2.38e-04	19	121	3	IPR013519
Domain	Prot_kinase_dom	NPR1 VRK2 CDK11A CIT PIM3 TRIB3 CSNK1D CSNK1E STK33 CDK11B PINK1	3.39e-04	489	121	11	IPR000719
Domain	PROTEIN_KINASE_DOM	NPR1 VRK2 CDK11A CIT PIM3 TRIB3 CSNK1D CSNK1E STK33 CDK11B PINK1	3.63e-04	493	121	11	PS50011
Domain	Tmemb_14	TMEM14A TMEM14DP	4.11e-04	5	121	2	PF03647
Domain	-	XDH LDHD	4.11e-04	5	121	2	3.30.43.10
Domain	FAD-bd_2_sub1	XDH LDHD	4.11e-04	5	121	2	IPR016167
Domain	TMEM14	TMEM14A TMEM14DP	4.11e-04	5	121	2	IPR005349
Domain	Ser/Thr_kinase_AS	VRK2 CDK11A CIT PIM3 CSNK1D CSNK1E STK33 CDK11B PINK1	5.31e-04	357	121	9	IPR008271
Domain	Integrin_dom	ITGA8 ITGA2B ITGA3	5.50e-04	25	121	3	IPR032695
Domain	S_TKc	VRK2 CDK11A CIT PIM3 TRIB3 CSNK1D STK33 CDK11B PINK1	5.53e-04	359	121	9	SM00220
Domain	PROTEIN_KINASE_ST	VRK2 CDK11A CIT PIM3 CSNK1D CSNK1E STK33 CDK11B PINK1	5.87e-04	362	121	9	PS00108
Domain	-	XDH LDHD	6.14e-04	6	121	2	3.30.465.10
Domain	FAD_PCMH	XDH LDHD	6.14e-04	6	121	2	PS51387
Domain	CO_DH_flavot_FAD-bd_sub2	XDH LDHD	6.14e-04	6	121	2	IPR016169
Domain	FAD-bd_2	XDH LDHD	6.14e-04	6	121	2	IPR016166
Domain	Intermediate_filament_CS	KRT6A KRT6B KRT75 KRT6C	7.43e-04	63	121	4	IPR018039
Domain	Kinase-like_dom	NPR1 VRK2 CDK11A CIT PIM3 TRIB3 CSNK1D CSNK1E STK33 CDK11B PINK1	7.98e-04	542	121	11	IPR011009
Domain	Filament	KRT6A KRT6B KRT75 KRT6C	1.17e-03	71	121	4	SM01391
Domain	IF	KRT6A KRT6B KRT75 KRT6C	1.23e-03	72	121	4	PS00226
Domain	Filament	KRT6A KRT6B KRT75 KRT6C	1.29e-03	73	121	4	PF00038
Domain	IF	KRT6A KRT6B KRT75 KRT6C	1.50e-03	76	121	4	IPR001664
Domain	TRP_channel	TRPV1 TRPV5	2.20e-03	11	121	2	IPR004729
Domain	Integrin_alpha	ITGA8 ITGA2B	2.20e-03	11	121	2	PF00357
Domain	COS	TRIM46 FSD1	2.63e-03	12	121	2	PS51262
Domain	COS_domain	TRIM46 FSD1	2.63e-03	12	121	2	IPR017903
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA4F NDST1 ZBTB4 ITGA3 ECE1 CIT ABCA7 MXRA7 LPIN3 PIM3 PHLDB1 KMT2D LLGL2 SCAP TRIB3 KCNG1 SLC25A39 HERC1 DMWD	1.27e-08	1105	123	19	35748872
Pubmed	Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.	KRT6A KRT6B ITGA2B ITGA3 PDIA3 SLC2A3 KRT6C STK33 PDE4DIP	3.77e-08	197	123	9	23686814
Pubmed	Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.	KRT6A KRT6B KRT6C	4.32e-08	3	123	3	29357356
Pubmed	Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.	KRT6A KRT6B KRT75	4.32e-08	3	123	3	17851587
Pubmed	Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles.	KRT6A KRT6B KRT75	4.32e-08	3	123	3	17170733
Pubmed	Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.	KRT6A KRT6B KRT6C	4.32e-08	3	123	3	7543104
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	TRIM46 GALNS CLIP2 TMEM14A ECE1 CIT PDIA3 SLC2A3 THRA ATIC	2.40e-07	322	123	10	26514267
Pubmed	Pachyonychia Congenita	KRT6A KRT6B KRT6C	4.29e-07	5	123	3	20301457
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SHANK1 TRIM46 KRT6A KRT6B SGIP1 LRCH2 CLIP2 OAT GRIN2A NDUFB5 CIT PDIA3 SLC2A3 WDR47 PHLDB1 CSNK1D IGHM PDE4DIP PRICKLE2	6.91e-07	1431	123	19	37142655
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 NDST1 CLIP2 ZBTB4 CRTAC1 OAT NDUFB5 CIT WDR47 NABP2 PDE4DIP IFT122 ATIC PADI2 NIPBL CUX1 PINK1	2.97e-06	1285	123	17	35914814
Pubmed	CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.	CSNK1D CSNK1E	1.24e-05	2	123	2	24424021
Pubmed	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.	KRT6A KRT6B	1.24e-05	2	123	2	10550543
Pubmed	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.	KRT6A KRT6B	1.24e-05	2	123	2	10550545
Pubmed	Effects of CB2 and TRPV1 Stimulation on Osteoclast Overactivity Induced by Iron in Pediatric Inflammatory Bowel Disease.	TRPV1 CNR2	1.24e-05	2	123	2	35472140
Pubmed	Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.	CSNK1D CSNK1E	1.24e-05	2	123	2	9632646
Pubmed	The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.	KRT6A KRT6B	1.24e-05	2	123	2	9790766
Pubmed	First "hybrid" ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands.	TRPV1 CNR2	1.24e-05	2	123	2	16406364
Pubmed	Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.	KRT6A KRT6B	1.24e-05	2	123	2	11489919
Pubmed	Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa.	KRT6A KRT6B	1.24e-05	2	123	2	10953016
Pubmed	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.	KRT6A KRT6B	1.24e-05	2	123	2	6207530
Pubmed	CDK11p58 Promotes Microglia Activation via Inducing Cyclin D3 Nuclear Localization.	CDK11A CDK11B	1.24e-05	2	123	2	28101846
Pubmed	Alteration of osteoclast activity in childhood cancer survivors: Role of iron and of CB2/TRPV1 receptors.	TRPV1 CNR2	1.24e-05	2	123	2	35862357
Pubmed	Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.	CSMD2 CSMD1	1.24e-05	2	123	2	24408017
Pubmed	Identification and characterization of a novel cell cycle-regulated internal ribosome entry site.	CDK11A CDK11B	1.24e-05	2	123	2	10882096
Pubmed	Structure and expression of the human p58clk-1 protein kinase chromosomal gene.	CDK11A CDK11B	1.24e-05	2	123	2	1639388
Pubmed	Increased expression of Trpv1 in peripheral terminals mediates thermal nociception in Fabry disease mouse model.	TRPV1 GLA	1.24e-05	2	123	2	27531673
Pubmed	Protein expression pattern of CDK11(p58) during testicular development in the mouse.	CDK11A CDK11B	1.24e-05	2	123	2	15792358
Pubmed	ITGA2B and ITGA8 are predictive of prognosis in clear cell renal cell carcinoma patients.	ITGA8 ITGA2B	1.24e-05	2	123	2	26198048
Pubmed	A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.	KRT6A KRT6B	1.24e-05	2	123	2	11118885
Pubmed	Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms.	CDK11A CDK11B	1.24e-05	2	123	2	8195233
Pubmed	Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.	CSNK1D CSNK1E	1.24e-05	2	123	2	19043076
Pubmed	Loss of Cldn5 -and increase in Irf7-in the hippocampus and cerebral cortex of diabetic mice at the early symptomatic stage.	IRF7 CLDN5	1.24e-05	2	123	2	39147772
Pubmed	Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma.	KRT6A KRT6C	1.24e-05	2	123	2	23662636
Pubmed	Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma.	CDK11A CDK11B	1.24e-05	2	123	2	7920654
Pubmed	Regulated expression of a cell division control-related protein kinase during development.	CDK11A CDK11B	1.24e-05	2	123	2	2069872
Pubmed	A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand.	CDK11A CDK11B	1.24e-05	2	123	2	7528743
Pubmed	Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.	CSNK1D CSNK1E	1.24e-05	2	123	2	25404202
Pubmed	Localization of the expressed human p58 protein kinase chromosomal gene to chromosome 1p36 and a highly related sequence to chromosome 15.	CDK11A CDK11B	1.24e-05	2	123	2	1774066
Pubmed	A genetic association study of CSMD1 and CSMD2 with cognitive function.	CSMD2 CSMD1	1.24e-05	2	123	2	27890662
Pubmed	Delayed wound healing in keratin 6a knockout mice.	KRT6A KRT6B	1.24e-05	2	123	2	10866680
Pubmed	The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.	CSMD2 CSMD1	1.24e-05	2	123	2	21439553
Pubmed	CDK11p110 plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.	CDK11A CDK11B	1.24e-05	2	123	2	30722725
Pubmed	Cytokeratins mediate epithelial innate defense through their antimicrobial properties.	KRT6A KRT6B	1.24e-05	2	123	2	23006328
Pubmed	The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer.	CDK11A CDK11B	1.24e-05	2	123	2	27049727
Pubmed	An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.	CSNK1D CSNK1E	1.24e-05	2	123	2	22981886
Pubmed	Failure to proliferate and mitotic arrest of CDK11(p110/p58)-null mutant mice at the blastocyst stage of embryonic cell development.	CDK11A CDK11B	1.24e-05	2	123	2	15060143
Pubmed	Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.	KRT6A KRT6B KRT75	2.34e-05	16	123	3	12399393
Pubmed	Virodhamine, an endocannabinoid, induces megakaryocyte differentiation by regulating MAPK activity and function of mitochondria.	TRPV1 CNR2	3.71e-05	3	123	2	32696508
Pubmed	Repression of estrogen receptor alpha by CDK11p58 through promoting its ubiquitin-proteasome degradation.	CDK11A CDK11B	3.71e-05	3	123	2	19122208
Pubmed	Identification of two new members of the CSMD gene family.	CSMD2 CSMD1	3.71e-05	3	123	2	12906867
Pubmed	Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice.	KRT6A KRT6B	3.71e-05	3	123	2	15601842
Pubmed	Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.	CSNK1D CSNK1E	3.71e-05	3	123	2	12270714
Pubmed	Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.	KRT6A KRT6B	3.71e-05	3	123	2	29587848
Pubmed	The novel long noncoding RNA AU021063, induced by IL-6/Arid5a signaling, exacerbates breast cancer invasion and metastasis by stabilizing Trib3 and activating the Mek/Erk pathway.	ARID5A TRIB3	3.71e-05	3	123	2	34389433
Pubmed	Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.	CSNK1D CSNK1E	3.71e-05	3	123	2	25724478
Pubmed	Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine.	XDH MOCOS	3.71e-05	3	123	2	22495427
Pubmed	A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.	CSNK1D CSNK1E	3.71e-05	3	123	2	25665722
Pubmed	CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.	CSNK1D CSNK1E	3.71e-05	3	123	2	32321936
Pubmed	A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.	KRT6A KRT6B	3.71e-05	3	123	2	14573483
Pubmed	Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.	CSNK1D CSNK1E	3.71e-05	3	123	2	28963394
Pubmed	Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.	CSNK1D CSNK1E	3.71e-05	3	123	2	31353086
Pubmed	Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.	CSNK1D CSNK1E	3.71e-05	3	123	2	8786104
Pubmed	CB2 and TRPV1 receptors mediate cannabinoid actions on MDR1 expression in multidrug resistant cells.	TRPV1 CNR2	3.71e-05	3	123	2	22814029
Pubmed	Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease.	XDH MOCOS	3.71e-05	3	123	2	19500084
Pubmed	Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesity.	CSNK1D CSNK1E	3.71e-05	3	123	2	27439882
Pubmed	Platelet-derived ERp57 mediates platelet incorporation into a growing thrombus by regulation of the αIIbβ3 integrin.	ITGA2B PDIA3	3.71e-05	3	123	2	24030382
Pubmed	The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinase in vivo.	CDK11A CDK11B	3.71e-05	3	123	2	9580558
Pubmed	A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.	TRPV1 TRPV5	3.71e-05	3	123	2	27291418
Pubmed	CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.	CSNK1D CSNK1E	3.71e-05	3	123	2	19805222
Pubmed	A role for keratins in supporting mitochondrial organization and function in skin keratinocytes.	KRT6A KRT6B	3.71e-05	3	123	2	32213122
Pubmed	Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.	CSNK1D CSNK1E	3.71e-05	3	123	2	22384121
Pubmed	Cannabinoid receptor 2 is critical for the homing and retention of marginal zone B lineage cells and for efficient T-independent immune responses.	IGHM CNR2	3.71e-05	3	123	2	22048769
Pubmed	Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3.	ITGA2B FGB	3.71e-05	3	123	2	9351824
Pubmed	The cyclin-dependent kinase 11(p46) isoform interacts with RanBPM.	CDK11A CDK11B	3.71e-05	3	123	2	14511641
Pubmed	Haploinsufficiency of the cdc2l gene contributes to skin cancer development in mice.	CDK11A CDK11B	3.71e-05	3	123	2	17389615
Pubmed	The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis.	CDK11A CDK11B	3.71e-05	3	123	2	12624090
Pubmed	CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model.	CDK11A CDK11B	3.71e-05	3	123	2	33664748
Pubmed	Contribution of Endocannabinoid Gene Expression and Genotype on Low Back Pain Susceptibility and Chronicity.	TRPV1 CNR2	3.71e-05	3	123	2	28481838
Pubmed	Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair.	KRT6A KRT6B	3.71e-05	3	123	2	14568992
Pubmed	Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.	KRT6A KRT6B	3.71e-05	3	123	2	1713533
Pubmed	Epithelial expression of vanilloid and cannabinoid receptors: a potential role in burning mouth syndrome pathogenesis.	TRPV1 CNR2	3.71e-05	3	123	2	24190005
Pubmed	IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.	ITGA8 ITGA2B ITGA3	4.71e-05	20	123	3	22687584
Pubmed	RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.	KRT6A KRT6B KRT75 KRT6C	5.09e-05	57	123	4	31862882
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	KRT6A KRT6B THRA KRT75 ACAA2	5.27e-05	113	123	5	34474245
Pubmed	The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation.	KRT6A KRT6B CLDN5	7.26e-05	23	123	3	19494835
Pubmed	Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.	ITGA8 ITGA2B ITGA3	7.26e-05	23	123	3	23152823
Pubmed	Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.	CSNK1D CSNK1E	7.41e-05	4	123	2	37578019
Pubmed	CDK11(p58) kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis.	CDK11A CDK11B	7.41e-05	4	123	2	24436071
Pubmed	The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.	CSNK1D CSNK1E	7.41e-05	4	123	2	20192920
Pubmed	A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3.	CDK11A CDK11B	7.41e-05	4	123	2	7777541
Pubmed	Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model.	CSNK1D CSNK1E	7.41e-05	4	123	2	31334659
Pubmed	Mouse models in preclinical studies for pachyonychia congenita.	KRT6A KRT6B	7.41e-05	4	123	2	16250208
Pubmed	Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle.	CDK11A CDK11B	7.41e-05	4	123	2	2217177
Pubmed	The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity.	GLA IGHM	7.41e-05	4	123	2	38359115
Pubmed	Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitro.	CSNK1D CSNK1E	7.41e-05	4	123	2	20421981
Pubmed	Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431.	KRT6A KRT6C	7.41e-05	4	123	2	9054461
Pubmed	Identification of curcumin-inhibited extracellular matrix receptors in non-small cell lung cancer A549 cells by RNA sequencing.	ITGA2B ITGA3	7.41e-05	4	123	2	28618934
Pubmed	Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2.	CDK11A CDK11B	7.41e-05	4	123	2	9750192
Pubmed	Association of genetic polymorphisms in the fibrinogen and platelet glycoprotein genes with unstable angina in Chinese patients.	ITGA3 FGB	7.41e-05	4	123	2	15346842
Pubmed	Involvement of casein kinase Iepsilon in cytokine-induced granulocytic differentiation.	CSNK1D CSNK1E	7.41e-05	4	123	2	15070676
Interaction	KRT26 interactions	KRT6A KRT6B KRT75 TRIB3 KRT6C	2.10e-06	35	122	5	int:KRT26
Interaction	PHTF1 interactions	KRT6A KRT6B KRT75 KRT6C	5.75e-06	20	122	4	int:PHTF1
GeneFamily	WD repeat domain containing	TBL3 WDR47 LLGL2 SCAP EML5 UTP15 IFT122 HERC1 DMWD DCAF12	2.06e-07	262	79	10	362
GeneFamily	Keratins, type II	KRT6A KRT6B KRT75 KRT6C	5.49e-06	27	79	4	609
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA8 ITGA2B ITGA3	6.25e-05	18	79	3	1160
Coexpression	TABULA_MURIS_SENIS_BLADDER_ENDOTHELIAL_CELL_AGEING	ZNF703 ITGA8 CDK11A XDH OAT ARID5A PIM3 GLA SLC16A3 CSNK1D CDK11B	4.28e-06	418	122	11	MM3681
Coexpression	GU_PDEF_TARGETS_DN	KRT6A KRT6B KRT75 KRT6C	3.59e-05	40	122	4	M10480
Coexpression	GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_UP	ECE1 ARID5A TRIB3 CSNK1D CSNK1E LOXL3 SLC38A3	4.06e-05	198	122	7	M9921
Coexpression	GSE27786_NKTCELL_VS_ERYTHROBLAST_UP	GALNS PSMA4 ECE1 WDR47 KMT2D CSNK1D CSNK1E	4.19e-05	199	122	7	M4865
Coexpression	GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP	ARID5A SLC2A3 MXRA7 PHLDB1 SLC16A3 CSNK1D PDE4DIP	4.19e-05	199	122	7	M7656
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_UP	LYSMD1 ITGA2B ECE1 LPIN3 PTPRG CLDN5 LOXL3	4.33e-05	200	122	7	M3964
Coexpression	GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN	ECE1 ARID5A LDHD EML5 CSNK1D STK33 ATIC	4.33e-05	200	122	7	M6372
Coexpression	GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN	CLIP2 XDH IRF7 PDIA3 ARID5A WDR47 LDHD	4.33e-05	200	122	7	M5096
Coexpression	GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP	KRT6A CDK11A DNAH7 SLC6A11 SLC16A3 IGHM PPIP5K1	4.33e-05	200	122	7	M5165
Coexpression	MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	SEMA4F RAB42 MSH4 GRIN2A GNMT SLC6A11 SLC16A3 KCNG1 PDE4DIP CLDN5 MOCOS	4.90e-05	544	122	11	M1936
Coexpression	MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	SEMA4F RAB42 MSH4 GRIN2A GNMT SLC6A11 SLC16A3 KCNG1 PDE4DIP CLDN5 MOCOS	7.91e-05	574	122	11	MM820
Coexpression	CAIRO_LIVER_DEVELOPMENT_DN	GNMT ABCA7 FGB ACAA2 HERC1 SLC38A3 PINK1	9.08e-05	225	122	7	M6175
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_DN	NPR1 SGIP1 ZBTB4 ITGA8 XDH MXRA7 PRICKLE2 ADGRF5 CLDN5 CNR2	1.03e-04	491	122	10	MM455
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 LYSMD1 PTPRG PRICKLE2 ADGRF5 CLDN5 IFT122	5.19e-07	175	121	7	98dc3b6f69a29d587f503898f09912700950e3d9
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ITGA3 PCDH12 MXRA7 PRICKLE2 ADGRF5 CLDN5	8.40e-07	188	121	7	51c6796a9488c056a10d048082015342c2e037f9
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ITGA3 PCDH12 MXRA7 PRICKLE2 ADGRF5 CLDN5	8.40e-07	188	121	7	b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCell	Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|World / Lineage, Cell type, age group and donor	GRIN2A ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	9.67e-07	192	121	7	1e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 XDH ITGA3 PTPRG PRICKLE2 ADGRF5 CLDN5	1.04e-06	194	121	7	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	4.53e-06	157	121	6	84f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCell	droplet-Lung-nan-3m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2B CIT SLC2A3 EML5 PADI2 DCAF12	6.91e-06	169	121	6	da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCell	droplet-Lung-nan-3m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2B CIT SLC2A3 EML5 PADI2 DCAF12	6.91e-06	169	121	6	a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ITGA8 HPSE LPIN3 PHLDB1 ADGRF5	9.59e-06	179	121	6	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	COPD-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.02e-05	181	121	6	61608123959483ff60f07d8467996853c4371b6a
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 PCDH12 ECE1 PIM3 ADGRF5 CLDN5	1.02e-05	181	121	6	2e15c46e8260bb04d8264478c19a707221996026
ToppCell	COPD-Endothelial-VE_Capillary_A\|COPD / Disease state, Lineage and Cell class	ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.12e-05	184	121	6	5f4f7775d488ececf086c71441defecbee9d8a9c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CRTAC1 TRIM71 ITGA3 CIT LLGL2 ADGRF5	1.19e-05	186	121	6	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	droplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6B NPR1 ECE1 FGB ADGRF5 CLDN5	1.23e-05	187	121	6	3827fa80e558b642f3e0036f5ee1a8b69f437e30
ToppCell	droplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6B NPR1 ECE1 FGB ADGRF5 CLDN5	1.23e-05	187	121	6	1bf696eb03422ea507d3efe58dda1d442a65225d
ToppCell	droplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6B NPR1 ECE1 FGB ADGRF5 CLDN5	1.23e-05	187	121	6	64dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCell	droplet-Lung-3m-Endothelial-venous_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6B NPR1 ECE1 FGB ADGRF5 CLDN5	1.23e-05	187	121	6	ebe4d1216cc0d4c079b413d5a5460cfd3a4af922
ToppCell	droplet-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6B NPR1 ECE1 FGB ADGRF5 CLDN5	1.23e-05	187	121	6	b535d5447bf15e95dcf025a0a455628b956fc857
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.23e-05	187	121	6	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.27e-05	188	121	6	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 KRT6A KRT6B SGIP1 ITGA3 PRICKLE2	1.31e-05	189	121	6	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GRIN2A PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.39e-05	191	121	6	1de0bdfd13bd930691564c2673f2e66393bc0255
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GRIN2A ITGA3 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.39e-05	191	121	6	f229abf69a1217194f74b0502486907e07dba989
ToppCell	facs-BAT-Fat-18m-Endothelial\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 XDH PCDH12 ECE1 ADGRF5 CLDN5	1.43e-05	192	121	6	3a99c521c599a289ee2309d97be5ceb99f8aa220
ToppCell	facs-BAT-Fat-18m-Endothelial-endothelial_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 XDH PCDH12 ECE1 ADGRF5 CLDN5	1.43e-05	192	121	6	f9777e0fdd86c2a514f05a42502888329a94b396
ToppCell	EC\|World / Lineage and Cell class	NPR1 PCDH12 ECE1 PIM3 ADGRF5 CLDN5	1.43e-05	192	121	6	478866dd5b0d6ff3a76d07a17c4b5989dd7a27bb
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GRIN2A PCDH12 PHLDB1 PRICKLE2 CLDN5 SARAF	1.43e-05	192	121	6	7197e401e563441ab94815f7619e032ebef9e586
ToppCell	droplet-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ITGA3 ECE1 MXRA7 ADGRF5 CLDN5	1.43e-05	192	121	6	42e4dafbe3e8b4a3c25d594f06b95430a1dd8b28
ToppCell	facs-BAT-Fat-18m-Endothelial-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 XDH PCDH12 ECE1 ADGRF5 CLDN5	1.43e-05	192	121	6	562e15876088af9189744c9b2de5c4863d7f15fd
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 XDH PTPRG PRICKLE2 ADGRF5 CLDN5	1.43e-05	192	121	6	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ITGA8 PCDH12 MXRA7 ADGRF5 CLDN5	1.43e-05	192	121	6	5890076929598e88fe9d59a4e4e858b446746ce9
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGIP1 ITGA3 MXRA7 PRICKLE2 ADGRF5 CLDN5	1.43e-05	192	121	6	35f7926628a967f85b26371e795a1b93c6f103ab
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ITGA8 PCDH12 MXRA7 ADGRF5 CLDN5	1.47e-05	193	121	6	4a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ITGA8 PCDH12 MXRA7 ADGRF5 CLDN5	1.47e-05	193	121	6	d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCell	AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	CRTAC1 GPAM CIT PTPRG ADGRF5 GJC3	1.47e-05	193	121	6	8187f976fd2d11fad3286690f1a046e894772220
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ITGA3 ECE1 MXRA7 ADGRF5 CLDN5	1.47e-05	193	121	6	ab54c4b8ae17580e2f2bfcdcb1456fe52dedafe9
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR1 ITGA8 ITGA3 PCDH12 ADGRF5 CLDN5	1.51e-05	194	121	6	8a4be91414a2e69dd410aa75791f16008204c9a1
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCDH12 ECE1 MXRA7 PTPRG ADGRF5 CLDN5	1.56e-05	195	121	6	d700e959e060932e3854a9cf294799465efbe18b
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DCDC1 DNAH7 PTPRG STK33 PRICKLE2 ADGRF5	1.61e-05	196	121	6	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DCDC1 DNAH7 PTPRG STK33 PRICKLE2 ADGRF5	1.61e-05	196	121	6	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NPR1 PCDH12 ECE1 PTPRG ADGRF5 CLDN5	1.65e-05	197	121	6	62c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NPR1 ITGA8 PCDH12 ECE1 ADGRF5 CLDN5	1.65e-05	197	121	6	9e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NPR1 PCDH12 ECE1 PTPRG ADGRF5 CLDN5	1.65e-05	197	121	6	16f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ECE1 PTPRG ADGRF5 CLDN5 SLC38A3 PINK1	1.70e-05	198	121	6	0a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	WNT9B CRTAC1 PPEF2 PCDH12 ADGRF5 CLDN5	1.70e-05	198	121	6	05429f18e1d74880c1835568c86177f661b3477a
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	WNT9B CRTAC1 PPEF2 PCDH12 ADGRF5 CLDN5	1.70e-05	198	121	6	306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCell	normal_Lung-Endothelial_cells-Tip-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.75e-05	199	121	6	72c96a5954dfcfbfee8f095984ce1f5249d9a679
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.75e-05	199	121	6	7ed541309808f15d65a9c4b26be2050e077539e6
ToppCell	control-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SPATA7 ZNF703 ZNF140 LGR6 PARPBP DCAF12	1.75e-05	199	121	6	50e2da35edff1aadef939cfbd4549f73c1a07717
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ITGA8 PCDH12 ECE1 PTPRG ADGRF5 CLDN5	1.75e-05	199	121	6	463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LYSMD1 KCNK12 KIAA1614 TBL3 GADD45GIP1 GJC3	1.75e-05	199	121	6	4e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NPR1 ITGA3 PCDH12 PHLDB1 ADGRF5 CLDN5	1.75e-05	199	121	6	14a7c4cf4bb3d43fd32ec9cc74f6625b225ffaa1
ToppCell	Kidney-Endothelial\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	NPR1 PCDH12 ECE1 SLC2A3 ADGRF5 CLDN5	1.75e-05	199	121	6	b543f0686522df43737e9ffa5c9733e42b8a9f4d
ToppCell	distal-3-Endothelial-Capillary_Aerocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ITGA3 PCDH12 PHLDB1 PRICKLE2 ADGRF5 CLDN5	1.80e-05	200	121	6	e12598a097dd9c4cbf9bb85bfa3057722ef73ad5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PHLDB1 PTPRG STK33 ADGRF5 CLDN5 SLC38A3	1.80e-05	200	121	6	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PHLDB1 PTPRG STK33 ADGRF5 CLDN5 SLC38A3	1.80e-05	200	121	6	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	NPR1 PCDH12 ECE1 SLC2A3 PTPRG ADGRF5	1.80e-05	200	121	6	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PHLDB1 PTPRG STK33 ADGRF5 CLDN5 SLC38A3	1.80e-05	200	121	6	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PHLDB1 PTPRG STK33 ADGRF5 CLDN5 SLC38A3	1.80e-05	200	121	6	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PHLDB1 PTPRG STK33 ADGRF5 CLDN5 SLC38A3	1.80e-05	200	121	6	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PHLDB1 PTPRG STK33 ADGRF5 CLDN5 SLC38A3	1.80e-05	200	121	6	7136936d05ab344a560cf159684c881063b5430d
ToppCell	LPS_only-Myeloid-Dendritic_cells-pDC\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRPV1 TTC39C IRF7 IGHM CNR2	3.40e-05	135	121	5	0afe232aa1a1e6c37a5b3183b67d7fa07e0ea791
ToppCell	droplet-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC39C OAT GNMT FGB SLC38A3	4.78e-05	145	121	5	f142b86d4da5b71c189da46cbc4beebdc387ffee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TRIM46 CCDC168 MSH4 ARID5A CLDN5	7.39e-05	159	121	5	299e2162a82e31196d7f3a110c2db622349edfff
ToppCell	356C-Fibroblasts-Fibroblast-D\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TRIM46 CCDC168 MSH4 ARID5A CLDN5	7.39e-05	159	121	5	0a3a363b30a8c741e1a3e2525725108d03c21776
ToppCell	PND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIM71 ITGA2B HPSE CIT SLC2A3	7.84e-05	161	121	5	52556b89808e551540f33a13f57417a6696c2438
ToppCell	PND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIM71 ITGA2B HPSE CIT SLC2A3	7.84e-05	161	121	5	54f156cf2bd5a6ba9a78ec4e3ee28b89998aec2e
ToppCell	PND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIM71 ITGA2B HPSE CIT SLC2A3	7.84e-05	161	121	5	242891be849a4398fe8bea44875ae1ba57950944
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	TRIM46 ITGA8 CCDC168 MSH4 ARID5A	9.06e-05	166	121	5	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	TRIM46 ITGA8 CCDC168 MSH4 ARID5A	9.06e-05	166	121	5	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CRTAC1 ITGA3 MXRA7 ADGRF5 LGR6	9.32e-05	167	121	5	dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	GNMT CIT PIM3 LDHD PHLDB1	9.86e-05	169	121	5	625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	CRTAC1 ITGA3 MXRA7 ADGRF5 LGR6	1.01e-04	170	121	5	4a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B SGIP1 LOXL3 GJC3	1.01e-04	170	121	5	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	Bronchial_Brush-Immune-B_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	KCNK12 IGHM PRICKLE2 PARPBP QRSL1	1.01e-04	170	121	5	53e9372cb06a2dc5c8ecb3f9af42f3c23da96431
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MSH4 GRIN2A ARID5A ADGRF5 LGR6	1.04e-04	171	121	5	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA2B SLC2A3 HERC1 PADI2 MOCOS	1.07e-04	172	121	5	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGIP1 ITGA8 TRIM71 PCDH12 PRICKLE2	1.07e-04	172	121	5	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA2B SLC2A3 HERC1 PADI2 MOCOS	1.07e-04	172	121	5	953b05f776348cff784e79c93df65841939d880f
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHANK1 GNMT PIM3 PADI2 SLC38A3	1.13e-04	174	121	5	165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRCH2 ITGA8 PHLDB1 PTPRG PRICKLE2	1.13e-04	174	121	5	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHANK1 GNMT PIM3 PADI2 SLC38A3	1.13e-04	174	121	5	4289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH12 HPSE ADGRF5 CLDN5 CNR2	1.19e-04	176	121	5	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH12 HPSE ADGRF5 CLDN5 CNR2	1.19e-04	176	121	5	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPR1 ECE1 FGB ADGRF5 CLDN5	1.19e-04	176	121	5	96779273b94345250cf53ba671203345b43d9e00
ToppCell	metastatic_Lymph_Node-Endothelial_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	NPR1 SGIP1 LRCH2 PCDH12 CLDN5	1.22e-04	177	121	5	71bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 RAB42 PRICKLE2 ADGRF5 CLDN5	1.22e-04	177	121	5	8ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 PTPRG KCNG1 ADGRF5 IFT122	1.26e-04	178	121	5	ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 PCDH12 PIM3 ADGRF5 CLDN5	1.26e-04	178	121	5	462111b61f37338f97ac7dc6c7da1d4316b54445
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH12 PTPRG KCNG1 ADGRF5 IFT122	1.26e-04	178	121	5	93ce73f8bcec63ebf86fabb546f88400e8f06465
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XDH IRF7 PIM3 ADGRF5 CLDN5	1.29e-04	179	121	5	fca111789d7354de7ae4cd38253aa0685c0cb2d2
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Pre-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNK12 IGHM STK33 QRSL1 DCAF12	1.29e-04	179	121	5	dc0b806904ef4c2f74f34ade2b1c0d6893f3b2ec
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XDH IRF7 PIM3 ADGRF5 CLDN5	1.29e-04	179	121	5	c3e53a3b8e59f7245d737386a1dd0f9d7aa5fb61
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NPR1 PCDH12 ECE1 CLDN5 SLC38A3	1.29e-04	179	121	5	d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 PCDH12 PHLDB1 ADGRF5 CLDN5	1.32e-04	180	121	5	755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 CRTAC1 ITGA2B PCDH12 CLDN5	1.32e-04	180	121	5	25f8e82bbc1853cb7d072484e99369c72779dd1e
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 SEMA4F SGIP1 GJC3 CSMD1	1.32e-04	180	121	5	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NPR1 PCDH12 SLC16A3 ADGRF5 CLDN5	1.32e-04	180	121	5	7d4cb0ab9f96088cbc5db3096d884a1e5ce4cb5d
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|367C / Donor, Lineage, Cell class and subclass (all cells)	NPR1 ITGA3 PCDH12 ADGRF5 CLDN5	1.32e-04	180	121	5	162cec1734e560c068cd61717e40e18dcf92308c
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	GPAM HPSE IFT122 DMWD PARPBP	1.32e-04	180	121	5	d1a8b25115c80e5a5bd0b8244167a98250ab9778
Drug	SC-791	KRT6A KRT6B KRT75 KRT6C	1.17e-08	6	122	4	CID010291510
Drug	PD153035	KRT6A KRT6B TRPV1 ITGA3 ECE1 KRT75 KRT6C CNR2	4.25e-07	127	122	8	CID000004705
Drug	AC1LAW6Y	GALNS CIT GLA	1.49e-06	5	122	3	CID000521877
Drug	clobestasol propionate	KRT6A KRT6B KRT75 KRT6C	1.77e-06	17	122	4	CID000002791
Drug	dithranol	KRT6A KRT6B KRT75 KRT6C	2.27e-06	18	122	4	CID000002202
Drug	Olux	KRT6A KRT6B KRT75 KRT6C	3.56e-06	20	122	4	CID000032797
Drug	elaidamide	TRPV1 GRIN2A CLDN5 TRPV5 CNR2	6.42e-06	49	122	5	CID000001930
Drug	CK2 inhibitor	GPAM GRIN2A CBLIF PIM3 CSNK1D CSNK1E	7.41e-06	87	122	6	CID000001694
Drug	MK-6	KRT6A KRT6B KRT75 KRT6C	7.67e-06	24	122	4	CID005283547
Drug	Bhg-(2-1)fuc	KRT6A KRT6B KRT75 KRT6C	9.10e-06	25	122	4	CID005287784
Drug	ethylnylestradiol	SPATA7 KRT6A KRT6B TRPV1 CLIP2 IRF7 GRIN2A PDIA3 SLC2A3 SLC6A11 THRA KRT75 PTPRG KRT6C FGB SARAF PARPBP QRSL1 ALPI MOCOS	1.07e-05	1251	122	20	CID000003285
Drug	betamethasone valerate	KRT6A KRT6B KRT75 KRT6C	1.45e-05	28	122	4	CID000016533
Drug	DL-arginine	NPR1 XDH OAT GRIN2A CIT SLC6A11 GLA SLC25A2 LOXL3 TRPV5	1.68e-05	344	122	10	CID000000232
Drug	2-Formyl-Protoporphryn Ix	KRT6A KRT6B KRT75 KRT6C	2.21e-05	31	122	4	CID011963946
Drug	AGN 193109	KRT6A KRT6B KRT75 KRT6C	2.21e-05	31	122	4	CID000177238
Drug	AC1NOWCG	XDH CBLIF SLC38A3 CNR2	2.51e-05	32	122	4	CID005120109
Drug	2-thiouric acid	XDH QRSL1	2.85e-05	2	122	2	CID003034255
Drug	2-amino-2-deoxygalacturonic acid	GALNS GLA	2.85e-05	2	122	2	CID000193487
Drug	sulfosuccinimidobiotin	KRT6A ITGA2B KRT6C	3.19e-05	12	122	3	CID000083894
Drug	tsuwabukinonol	KRT6A KRT6B GPAM KRT6C	4.52e-05	37	122	4	CID006440419
Drug	chrysarobin	KRT6A KRT6B KRT75 KRT6C	4.52e-05	37	122	4	CID000068111
Drug	CaLam	KRT6A KRT6B KRT75 KRT6C	5.58e-05	39	122	4	CID004126474
Drug	sn-3	GPAM PDIA3 GLA SLC38A3	7.50e-05	42	122	4	CID016040239
Drug	homocysteine thiolactone	KRT6A KRT6B CBLIF KRT75 KRT6C ATIC	7.57e-05	131	122	6	CID000107712
Drug	beta-aminobutyric acid	NPR1 SLC6A11 MOCOS	7.99e-05	16	122	3	CID000010932
Drug	AC1L9MJT	KRT6A KRT6B CLIP2 SLC2A3 KRT75 KRT6C QRSL1	8.04e-05	192	122	7	CID000448959
Drug	arabinopyranose	GALNS XDH NDUFB5 TBL3 SLC2A3 GLA FGB ALPI	8.37e-05	261	122	8	CID000000229
Drug	Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; HL60; HT_HG-U133A	IRF7 PCDH12 DNAH7 ARID5A SLC16A3 KCNG1 CNR2	8.86e-05	195	122	7	2364_UP
Drug	Butylparaben [94-26-8]; Up 200; 20.6uM; PC3; HT_HG-U133A	NPR1 SLC2A3 CBLIF FCAR PDE4DIP FGB ALPI	8.86e-05	195	122	7	4647_UP
Drug	Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A	ECE1 ABCA7 ARID5A SLC2A3 FCAR FGB CNR2	8.86e-05	195	122	7	2317_UP
Drug	Prednisolone [50-24-8]; Down 200; 11uM; MCF7; HT_HG-U133A	IRF7 ECE1 PHLDB1 SLC16A3 KCNG1 CSNK1E PDE4DIP	9.15e-05	196	122	7	7424_DN
Drug	ammonia	GALNS XDH OAT GRIN2A CIT THRA MOCS3 SLC25A2 FGB LOXL3 PADI2	9.42e-05	509	122	11	CID000000222
Drug	Dydrogesterone [152-62-5]; Up 200; 12.8uM; HL60; HT_HG-U133A	NPR1 CLIP2 ECE1 FCAR PDE4DIP DMWD PADI2	9.44e-05	197	122	7	2156_UP
Drug	Lactobionic acid [96-82-2]; Up 200; 11.2uM; PC3; HT_HG-U133A	SEMA4F ZNF140 XDH CBLIF PHLDB1 THRA PDE4DIP	9.44e-05	197	122	7	6605_UP
Drug	Roxarsone [121-19-7]; Down 200; 15.2uM; MCF7; HT_HG-U133A	SEMA4F TRPV1 FSD1 PTPRG CSNK1E PDE4DIP DMWD	9.75e-05	198	122	7	3511_DN
Drug	Nadolol [42200-33-9]; Up 200; 13uM; HL60; HT_HG-U133A	XDH FSD1 KCNK12 CBLIF KMT2D KCNG1 PDE4DIP	1.04e-04	200	122	7	3020_UP
Disease	Hereditary xanthinuria	XDH MOCOS	1.53e-05	2	116	2	cv:C5779508
Disease	Schizophrenia	SHANK1 VRK2 ITGA8 GRIN2A CSMD2 CBLIF SLC6A11 EML5 CSNK1E CLDN5 CSMD1 CNR2 PINK1	4.55e-05	883	116	13	C0036341
Disease	Pachyonychia congenita syndrome	KRT6A KRT6B	9.15e-05	4	116	2	cv:C0265334
Disease	Pachyonychia Congenita, Jadassohn Lewandowsky Type	KRT6A KRT6B	9.15e-05	4	116	2	C1706595
Disease	pachyonychia congenita (is_implicated_in)	KRT6A KRT6B	9.15e-05	4	116	2	DOID:0050449 (is_implicated_in)
Disease	Pachyonychia Congenita, Type 2 (disorder)	KRT6A KRT6B	9.15e-05	4	116	2	C1721007
Disease	Pachyonychia Congenita	KRT6A KRT6B	1.52e-04	5	116	2	C0265334
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1D CSNK1E	3.18e-04	7	116	2	DOID:0060807 (implicated_via_orthology)
Disease	pulmonary function measurement, forced expiratory volume	PSMA4 TRIM71 SLC6A11	4.17e-04	37	116	3	EFO_0003892, EFO_0004314
Disease	pancreatitis (biomarker_via_orthology)	XDH FGB CNR2	4.88e-04	39	116	3	DOID:4989 (biomarker_via_orthology)
Disease	hyperhomocysteinemia (implicated_via_orthology)	GRIN2A ECE1	8.23e-04	11	116	2	DOID:9279 (implicated_via_orthology)
Disease	amyloid plaque accumulation rate	MOCS3 KCNG1	9.86e-04	12	116	2	EFO_0007646
Disease	serum urea measurement	TRIM46 DCDC1 WNT9B SLC16A3 LGR6	1.06e-03	195	116	5	EFO_0009795
Disease	cataract (biomarker_via_orthology)	XDH SLC2A3	1.16e-03	13	116	2	DOID:83 (biomarker_via_orthology)
Disease	post-traumatic stress disorder	VRK2 PCDHA7 GRIN2A LGR6 CSMD1	1.24e-03	202	116	5	EFO_0001358
Disease	facial morphology	ITGA8 GPAM CSMD1	1.34e-03	55	116	3	EFO_0004743
Disease	C-X-C motif chemokine 11 measurement	PPEF2 CUX1	1.35e-03	14	116	2	EFO_0008057
Disease	Eye Abnormalities	NDST1 IFT122	2.00e-03	17	116	2	C0015393
Disease	blood urea nitrogen measurement	TRIM46 DCDC1 WNT9B KIAA1614 PHLDB1 SLC16A3 LGR6	2.10e-03	452	116	7	EFO_0004741
Disease	magnesium measurement	TRIM46 DCDC1 CCDC168	2.26e-03	66	116	3	EFO_0004845
Disease	Malignant neoplasm of liver	PSMA4 OAT GNMT PRICKLE2	2.43e-03	142	116	4	C0345904
Disease	Liver neoplasms	PSMA4 OAT GNMT PRICKLE2	2.43e-03	142	116	4	C0023903
Disease	atypical femoral fracture, response to bisphosphonate	GALNS KCNG1 CSMD1	2.46e-03	68	116	3	EFO_0009958, EFO_0009960
Disease	stroke, major depressive disorder	VRK2 PTPRG	2.51e-03	19	116	2	EFO_0000712, MONDO_0002009
Disease	Major Depressive Disorder	XDH IRF7 HPSE CUX1 PINK1	2.78e-03	243	116	5	C1269683
Disease	melanoma	GPAM GRIN2A HPSE SLC6A11 CUX1	3.03e-03	248	116	5	C0025202
Disease	cardiovascular system disease (is_implicated_in)	XDH FGB	3.06e-03	21	116	2	DOID:1287 (is_implicated_in)
Disease	intellectual disability (implicated_via_orthology)	NDST1 ITGA8 ITGA2B	3.25e-03	75	116	3	DOID:1059 (implicated_via_orthology)
Disease	carotid artery disease (is_implicated_in)	XDH FGB	3.36e-03	22	116	2	DOID:3407 (is_implicated_in)
Disease	schizophrenia (is_implicated_in)	ITGA8 GRIN2A CLDN5	3.63e-03	78	116	3	DOID:5419 (is_implicated_in)
Disease	Unipolar Depression	IRF7 HPSE CUX1 CNR2 PINK1	3.65e-03	259	116	5	C0041696
Disease	autism spectrum disorder symptom	CLIP2 ITGA8	3.67e-03	23	116	2	EFO_0005426

Protein segments in the cluster

Peptide	Gene	Start	Entry
DYFVSGAGLPGRFKA	PTPRG	131	P23470
PSAFHKGGSRKGILY	ARID5A	396	Q03989
GIPAYGKRTGSSFLH	CSMD1	531	Q96PZ7
PRYGKRLGSDFSVGA	CSMD2	1741	Q7Z408
GPRSYTIAVASLGKG	GLA	361	P06280
PLGKNDGAVAGTRYF	CLIP2	256	Q9UDT6
LKVGDFGLAREYGSP	CDK11B	576	P21127
TRAGPSYAKLGDFVA	NPR1	156	P16066
GFYKLLPGDGAARRS	DMWD	31	Q09019
LPKAGSITYRFGSAG	DMWD	421	Q09019
FVGFSYSKALGILGR	CIT	416	O14578
RPAGTYSGGNKRKLA	ABCA7	1921	Q8IZY2
RKPSYLFIGSLAGAD	CNR2	66	P34972
GKTSLLRSYVAGAPG	RAB42	21	Q8N4Z0
SFIRTIELGGKGYAP	PARPBP	226	Q9NWS1
RGNKYLAKPGGSRSA	PCDH12	981	Q9NPG4
LGGGPLTGILYSYSK	OR7A5	206	Q15622
AGASIPFRVGLYTGE	PCDHA7	616	Q9UN72
KRYNSVLFGGLIGSA	MFSD10	81	Q14728
FRLVLLAASGPGVYG	GJC3	31	Q8NFK1
DGYRNGKLIVAGTFP	DCDC1	1421	M0R2J8
KELYRGLNPATLSGG	LPIN3	16	Q9BQK8
FGSRSLYGLGGSKRI	KRT6C	56	P48668
KAGSQGLRFRLAGFP	LOXL3	36	P58215
SGGGYLNIKASTFPV	IFT122	571	Q9HBG6
KSGRSYVGIGLPGLS	TRIM71	581	Q2Q1W2
PGDTLAGLALKYGVT	LYSMD1	46	Q96S90
TRSGAIKLYGAPGVE	LLGL2	51	Q6P1M3
FGSRSLYGLGGSKRI	KRT6A	56	P02538
AGFVAGLGKVRPYSV	SLC16A3	281	O15427
AYGKSPSLGSVRAGV	LGR6	676	Q9HBX8
SKAFGVGVAYRSLGR	FSD1	366	Q9BTV5
PFAVGYFDGKLLLGT	HERC1	3596	Q15751
KGNRSSLYLVAGPGD	KIAA1614	1076	Q5VZ46
IKFLQSYPGRGSGSD	CUX1	551	Q13948
GLYGKPFLSADRGLV	FCAR	121	P24071
ISGGGYRARPAKAAA	FGB	66	P02675
ALLLRFTGKPGRAYG	PINK1	16	Q9BXM7
KLGLPGLATFGYSLS	ITGA3	421	P26006
FGSRSLYGLGGSKRI	KRT6B	56	P04259
TPATVGGKAFLIAYG	KCNK12	136	Q9HB15
LGRKIGSGSFGDIYL	CSNK1D	11	P48730
FPSYLLGGRSGALKN	NIPBL	941	Q6KC79
GPQKTGTTALYLFLG	NDST1	611	P52848
GAGLGFSTAPNKIFY	KNOP1	431	Q1ED39
AAPLLRKTYFGGGTA	MOCOS	281	Q96EN8
PGAFGTILTFLRAGK	KCNG1	121	Q9UIX4
YLGFGQDLSAGRPKE	IRF7	431	Q92985
GQDGSPGLSKFRLSY	GNMT	231	Q14749
GKTYPLGRILIGSSF	PADI2	421	Q9Y2J8
GLSPAYLRFGGTKTD	HPSE	86	Q9Y251
GAFGTGKVAVYRARP	ITGA8	471	P53708
YTLRGSSIFGLAPSK	ALPI	386	P09923
YGLPKSSTLGGRGQL	PRICKLE2	816	Q7Z3G6
ASKPFLGTSQRGRYG	GALNS	241	P34059
KIPVGSEEGYRSLFG	CBLIF	186	P27352
SSTRGFPSVLRGGKY	IGHM	51	P01871
VGFKPSYGLVSRHGL	QRSL1	206	Q9H0R6
YDSSGTKLFVAGGPL	DCAF12	426	Q5T6F0
GRRKSAAGYNLTGLF	LDHD	231	Q86WU2
PFGGKTSAYRVLAGA	DNAH7	1611	Q8WXX0
VGDFGLAREYGSPLK	CDK11A	566	Q9UQ88
FARYGAASGVVPGSL	GADD45GIP1	61	Q8TAE8
YIGEISPTALRGAFG	SLC2A3	141	P11169
KYTGGRGVSVGPILS	CRTAC1	236	Q9NQ79
SDIRFSPGSGKYLAV	EML5	1086	Q05BV3
PFYTRSSPKALNFGG	ECE1	586	P42892
GYLTSNTKGIGLLFP	CCDC168	3296	Q8NDH2
IYFTGFGTIRSGKRP	CCDC168	5661	Q8NDH2
DLLFGVPGKYSGVSL	SCAP	211	Q12770
YTQFGGKRPFGVSLL	PSMA4	121	P25789
LKIAAGLGPSYSGSL	MOCS3	261	O95396
SGRKLRDFPGSGYDL	LRCH2	96	Q5VUJ6
GSNRGAYVKLGPALT	PPEF2	516	O14830
PSGGLLVSAGGRYVK	UTP15	216	Q8TED0
RLDRLLKSGFGTYPG	TRIM46	101	Q7Z4K8
QLGYRAFGTPGKLAA	SLC38A3	131	Q99624
YTFGRILGKGSFGIV	STK33	116	Q9BYT3
LPLALAKRGSGFGGF	SEMA4F	726	O95754
GILGYLFGSNRAATP	SARAF	271	Q96BY9
LGGGPLTGILYSYSK	OR7A10	206	O76100
GVSGYPTLKIFRDGE	PDIA3	96	P30101
YAVLNKRGLGGPTST	GPAM	591	Q9HCL2
FGVLNYTKTPGGSRR	MSH4	336	O15457
TQLYGRFGSAIAPLG	ITGA2B	381	P08514
GKALSGGLYPVSAVL	OAT	291	P04181
AQVGLRGFYKGTGPA	SLC25A2	56	Q9BXI2
QKREGIGYPFLGAAT	ERVK-9	926	P63128
GYRAGLGSQEKSLPA	SHANK1	1421	Q9Y566
LETAFRKGYGILPGF	ADGRF5	201	Q8IZF2
GPAKARVALTGGVLY	CLDN5	111	O00501
AAKRTPFGAYGGLLK	ACAA2	11	P42765
PFGAYGGLLKDFTAT	ACAA2	16	P42765
PAGGLYAVGSNSKTL	WDR47	616	O94967
EKLLAAYPGASGLGS	ZNF703	491	Q9H7S9
TRGKFILSIAYSPDG	WDR61	146	Q9GZS3
RAESGTKGLFAGFLP	SLC25A39	311	Q9BZJ4
FRSGKLLQVGYTPDG	TRPV1	721	Q8NER1
GKFYLTFEGSSRGPS	SGIP1	536	Q9BQI5
KSPGLYFLTAGDQGT	TBL3	256	Q12788
GKIRRGAYALPAGLS	TRIB3	271	Q96RU7
SVFKGCLTLYTGRGG	NABP2	76	Q9BQ15
AIGGTYLGPAFRGLK	SPSB2	181	Q99619
GIVGYVKTGRAPSLA	TMEM14DP	26	A8MWL7
LVTFGSIFGYKRRGG	TMEM14A	11	Q9Y6G1
SIFGYKRRGGVPSLI	TMEM14A	16	Q9Y6G1
RTLTYTAKPVGGIGG	ZBTB4	566	Q9P1Z0
RLGFGGFLTRGFPKA	NDUFB5	26	O43674
RGVTLPGASEGIKFY	SLC6A11	271	P48066
AASGPRKLSSGALYG	SPATA7	186	Q9P0W8
ITGGRHPFLARYKVG	XDH	836	P47989
FGTVYAGSRIADGLP	PIM3	51	Q86V86
KGSFSGRLSPAYSLG	PHLDB1	531	Q86UU1
AKRSGVAYIAAPSGS	ATIC	551	P31939
GVFSFLGLFPKGQRA	PLAAT1	151	Q9HDD0
RILSQGPVYSSFKGG	ZNF140	106	P52738
SSILYKGAAAEGRPG	THRA	376	P10827
SLNRLKGAVSFGYGL	TTC39C	211	Q8N584
ALPAAAASYFGLTGR	WNT9B	16	O14905
PLFYGSGLTEFKGRS	VRK2	101	Q86Y07
YPSSAGGGSQRLFRK	PPIP5K1	211	Q6PFW1
GASRYFGKTILGGPF	TRPV5	411	Q9NQA5
LGRKIGSGSFGDIYL	CSNK1E	11	P49674
RKALFAVGVGRPSFG	KMT2D	1786	O14686
SFGSRSLYNLGGAKR	KRT75	56	O95678
GEGFSFKYSPGKLRG	MXRA7	136	P84157
LGRILEPGYLGSSGK	PDE4DIP	1796	Q5VU43
FATTGYGIALQKGSP	GRIN2A	756	Q12879