Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCCDC74

CCDC74B CCDC74A

8.24e-0521702IPR033226
DomainCCDC74_C

CCDC74B CCDC74A

8.24e-0521702IPR029422
DomainCCDC74_C

CCDC74B CCDC74A

8.24e-0521702PF14917
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ARHGEF19 SHROOM3 BCAS3 SPEG HECTD4 TASP1 KDM3B PEX6 PAPLN IRS1 MAST2 CIC PPP1R26 NHSL1 TKFC INF2 CASKIN1 ZNRF1 TLN2 ATG9A SLC45A1 HECTD1 IQCE TJP3

2.71e-0911051782435748872
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PDE4D CLASP1 NUMBL WFS1 BCAS3 KLC2 PGM1 SLC12A5 PITPNM1 NHSL1 KRT76 KHDRBS1 RNPEP INF2 FAM120C KIAA1217 CASKIN1 RBMX MACF1 TLN2 TAF15 USP54 ATP1A2 PLCH1 HSP90AA1 HDLBP

2.16e-0814311782637142655
Pubmed

Functional proteomics mapping of a human signaling pathway.

SMG1 SUMF2 ZMYND8 KDM3B PEX6 CUEDC1 PPP1R26 ABRAXAS2 KANK1 KHDRBS1 PIAS3 RNPEP NOM1 MACF1 EPN1 HDLBP

7.59e-085911781615231748
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SLAIN2 SHROOM3 CLASP1 NUMBL KIF26B BCAS3 KDM3B KLC2 IRS1 MAST2 CIC RUSC2 NHSL1 HAUS8 KIAA1217 MACF1 USP54 PLCH1 HECTD1

1.08e-078611781936931259
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SLAIN2 CNOT11 SHROOM3 CLASP1 NUMBL DHX40 RBMS1 COX5B ZMYND8 TASP1 TNRC6B RRAS TERF2 CIC CUEDC1 WDR3 FAM120C NOM1 RBM6 MACF1 BOP1 TAF15 EPN1 HDLBP

7.63e-0714971782431527615
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF219 ZNF180 MKRN2 ZMYND8 ZBTB22 KDM3B AIRE RUNX3 CXXC1 CIC RXRB ZNF750 TSC22D1 HMGA2 PIAS3 ZBTB5 KDM4B

1.01e-068081781720412781
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

HECW1 WFS1 BCAS3 COX5B KLC2 TNRC6B GPRIN1 ITPR1 PITPNM1 NHSL1 FRMD4A AMER2 FAM120C KIAA1217 CASKIN1 MACF1 TLN2 ATP1A2 HSP90AA1 HDLBP

1.77e-0611391782036417873
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

NUMBL BCAS3 GPRIN1 RUSC2 PITPNM1 AMER2 EFNB1 CASKIN1 MACF1 ATP1A2 SAMD14

1.97e-063471781117114649
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

CELF6 RBMXL1 RBMS1 RBMS2 KLHL3 KHDRBS1 RNPEP RBMX RBM6 TAF15 HDLBP

1.97e-063471781116033648
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHROOM3 ZNF219 HECW1 CLASP1 NUMBL HECTD4 ZBTB22 TNRC6B SLC12A5 FAM120C KIAA1217 CASKIN1 MACF1 TLN2 TAF15 QSER1 TACC3 HSP90AA1

2.54e-069631781828671696
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

CCDC134 SLAIN2 SUMF2 NUMBL JAGN1 RBMS1 MKRN2 TNRC6B GPRIN1 CXXC1 HAUS8 EFNB1 KHDRBS1 RBM6 SEC61B RP9 ATP1A2 EPN1

4.70e-0610071781834597346
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

CCDC134 ATG16L1 DUSP1 MKRN2 ZMYND8 KLC2 MAST2 PITPNM1 ABRAXAS2 WDR3 GARIN3 KRT76 CMIP GAS2L2 CSNK1G3 NOM1 RBMX IKBKB KDM4B HSP90AA1

6.43e-0612421782030973865
Pubmed

RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery.

KLC2 RUSC2 ATG9A

7.24e-068178334432492
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

ERCC5 HECTD4 KDM3B CUEDC1 KHDRBS1 RLIM MACF1 IKBKB EPN1 HECTD1 HACD1 HDLBP

7.79e-064811781228190767
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ERCC5 CLASP1 ZMYND8 KDM3B KLC2 GPRIN1 TERF2 CIC PITPNM1 RBMX RBM6 TLN2 TACC3 KDM4B HDLBP

1.18e-057741781515302935
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ZNF219 ZNF180 ZBTB22 POU4F2 RUNX3 CXXC1 CIC RXRB KHDRBS1 PIAS3 NFATC4 RBMX RLIM ZBTB5 IKBKB KDM4B

1.27e-058771781620211142
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CNOT11 COL12A1 KIF26B RBMS2 MAST2 TERF2 CXXC1 CIC PPP1R26 NHSL1 GARIN3 KANK1 INF2 RLIM

1.39e-056891781436543142
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

ADAMTS1 SPEG NHSL1 FRMD4A CASKIN1 RTL9 ALPK3

1.48e-05153178710718198
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

HECW1 CIC RUSC2 ZBTB5 TLN2 IGSF1

1.65e-0510417869205841
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZNF219 MKRN2 ZMYND8 ZBTB22 HIF3A CIC RXRB PIAS3 NFATC4 ZNRF1 MACF1 BOP1 TACC3 KDM4B

1.90e-057091781422988430
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SLAIN2 SMG1 SHROOM3 HECTD4 KDM3B CASKIN1 ZBTB5 BOP1 IGSF1 ATP1A2 KDM4B IQCE

2.00e-055291781214621295
Pubmed

Protein phosphatase 1α interacting proteins in the human brain.

CXXC1 KANK1 PIAS3 SH3RF2 SLC45A1

2.48e-0567178522321011
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

KLC2 TNRC6B KHDRBS1 RNPEP NFATC4 TAF15 HSP90AA1

2.50e-05166178735687106
Pubmed

IFIT3 accelerates the progression of head and neck squamous cell carcinoma by targeting PD-L1 to activate PI3K/AKT signaling pathway.

PDCD1 IFIT3

2.60e-052178238273364
Pubmed

Mesenchymal Cell Invasion Requires Cooperative Regulation of Persistent Microtubule Growth by SLAIN2 and CLASP1.

SLAIN2 CLASP1

2.60e-052178227939686
Pubmed

Malfunction of respiratory-related neuronal activity in Na+, K+-ATPase alpha2 subunit-deficient mice is attributable to abnormal Cl- homeostasis in brainstem neurons.

SLC12A5 ATP1A2

2.60e-052178215564586
Pubmed

Requirement for high mobility group protein HMGI-C interaction with STAT3 inhibitor PIAS3 in repression of alpha-subunit of epithelial Na+ channel (alpha-ENaC) transcription by Ras activation in salivary epithelial cells.

HMGA2 PIAS3

2.60e-052178211390395
Pubmed

IκB kinase β regulates epithelium migration during corneal wound healing.

KRT12 IKBKB

2.60e-052178221264230
Pubmed

Methods to analyze SNARE-dependent vesicular fusion events that regulate autophagosome biogenesis.

ATG16L1 ATG9A

2.60e-052178225461811
Pubmed

Mammalian autophagy and the plasma membrane.

ATG16L1 ATG9A

2.60e-052178227758042
Pubmed

SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins.

RBMS1 RBMS2

2.60e-05217828041632
Pubmed

CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.

CCDC74B CCDC74A

2.60e-052178231521166
Pubmed

PD-1 cooperates with AIRE-mediated tolerance to prevent lethal autoimmune disease.

PDCD1 AIRE

2.60e-052178235394861
Pubmed

Structures and comparison of genomic and complementary DNAs of mouse MSSP, a c-Myc binding protein.

RBMS1 RBMS2

2.60e-052178210639566
Pubmed

Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways.

IRS1 IKBKB

2.60e-052178222766331
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

SLAIN2 GALC PDE4D RBMS1 RBMS2 MAST2 FRMD4A KHDRBS1 NOM1 KIAA1217 TAF15 ASPRV1 PLCH1 IQCE

2.70e-057321781434732716
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 DHX40 KDM3B PEX6 PAPLN MAST2 ITPR1 RUSC2 NOM1 QSER1 PLCH1 EPN1 SLC27A4

3.34e-056501781338777146
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SUMF2 CLASP1 PLEKHG4 WFS1 JAGN1 PEX6 PGM1 TKFC CMIP EFNB1 RNPEP SEC61B MACF1 SGCE ATG9A SLC45A1 EPN1

3.51e-0510611781733845483
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

CLASP1 MAST2 MACF1 SGCE

3.84e-0537178427565344
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

CLASP1 SLC12A5 ITPR1 CSNK1G3 MACF1 SGCE

5.34e-05128178630995482
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

CCDC134 ERCC5 HECW1 NUMBL PLEKHG4 ZMYND8 KLC2 TNRC6B CXXC1 CIC PTPRN USP54

7.63e-056081781216713569
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

SMG1 RBMS1 RBMS2 MKRN2 KHDRBS1 FAM120C NOM1 RBMX RBM6 MACF1 TAF15 RP9 HSP90AA1 HDLBP

7.68e-058071781422681889
Pubmed

RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response to high-fructose diet.

RBMXL1 RBMX

7.79e-053178217188681
Pubmed

RBMY evolved on the Y chromosome from a ubiquitously transcribed X-Y identical gene.

RBMXL1 RBMX

7.79e-053178210391207
Pubmed

Sam68 interacts with IRS1.

IRS1 KHDRBS1

7.79e-053178222005517
Pubmed

Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62, and GTPase-activating protein.

IRS1 KHDRBS1

7.79e-05317828175658
Pubmed

Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS.

RBMX TAF15

7.79e-053178227460707
Pubmed

AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A.

RUSC2 ATG9A

7.79e-053178230262884
Pubmed

Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus.

AIRE ASPRV1

7.79e-053178230534943
Pubmed

Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia.

RBMXL1 RBMX

7.79e-053178234458856
Pubmed

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307).

IRS1 IKBKB

7.79e-053178210722755
Pubmed

Curcumin suppresses NTHi-induced CXCL5 expression via inhibition of positive IKKβ pathway and up-regulation of negative MKP-1 pathway.

DUSP1 IKBKB

7.79e-053178227538525
Pubmed

Regulation of type 1 IP₃ receptor expression by dopamine D2-like receptors via AP-1 and NFATc4 activation.

ITPR1 NFATC4

7.79e-053178223597509
Pubmed

Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme.

HECTD1 HSP90AA1

7.79e-053178222431752
Pubmed

Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation.

ITPR1 MACF1 HSP90AA1

8.50e-0517178320395553
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZMYND8 MAST2 CIC FRMD4A TLN2

8.74e-0587178512465718
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

SLAIN2 ATG16L1 CNOT11 CLASP1 NUMBL BCAS3 RBMS1 RBMS2 MKRN2 KDM3B RUSC2 ABRAXAS2 HAUS8 KIAA1217 EPN1 TJP3

9.42e-0510381781626673895
Pubmed

rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions.

SLAIN2 CLASP1 KLC2 WDR3 RBM6 TACC3

9.50e-05142178630217970
Pubmed

SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression.

ZMYND8 PIAS3 INF2

1.02e-0418178329996942
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

SHROOM3 CLASP1 RBMXL1 TNRC6B CHD1L ITPR1 KANK1 KIAA1217 RBM6 TLN2 HECTD1

1.08e-045361781115840001
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

CLASP1 MKRN2 CHD1L MAST2 F5 KHDRBS1 RBMX MACF1 TLN2

1.10e-04361178926167880
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CLASP1 KDM3B TNRC6B HAUS8 KANK1 ZNF792 NFATC4 SEC61B QSER1 USP54 PLCH1 HECTD1 SLC27A4

1.12e-047331781334672954
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

SHROOM3 CLASP1 RBMXL1 TNRC6B CHD1L ITPR1 KANK1 KIAA1217 RBM6 TLN2 HECTD1

1.12e-045381781110512203
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TCEA2 RBMS1 RBMS2 ZMYND8 CIC WDR3 KHDRBS1 RBMX RBM6 SEC61B TAF15 RP9 QSER1 HSP90AA1 HDLBP

1.26e-049541781536373674
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

GALC CLASP1 RBMXL1 NUMBL ZMYND8 HECTD4 TNRC6B CXXC1 HMGA2 KHDRBS1 RBMX RBM6 SEC61B MACF1 TAF15 HSP90AA1

1.51e-0410821781638697112
Pubmed

Insulin promotes the association of heat shock protein 90 with the inositol 1,4,5-trisphosphate receptor to dampen its Ca2+ release activity.

ITPR1 HSP90AA1

1.55e-044178219147678
Pubmed

Arginine methylation regulates telomere length and stability.

TERF2 KHDRBS1

1.55e-044178219596784
Pubmed

Prolyl hydroxylase-3 is down-regulated in colorectal cancer cells and inhibits IKKbeta independent of hydroxylase activity.

IKBKB HSP90AA1

1.55e-044178219786027
Pubmed

Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase.

KDM4B HSP90AA1

1.55e-044178223589305
Pubmed

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action.

IRS1 IKBKB

1.55e-044178211606564
Pubmed

SAFB1, an RBMX-binding protein, is a newly identified regulator of hepatic SREBP-1c gene.

RBMXL1 RBMX

1.55e-044178219403048
Pubmed

S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2.

IRS1 IKBKB

1.55e-044178218952604
Pubmed

Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms.

RXRB TACC3

1.55e-044178215207008
Pubmed

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response.

ATG16L1 ATG9A

1.55e-044178219926846
Pubmed

Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy.

ATG16L1 ATG9A

1.55e-044178221068542
Pubmed

Intermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar Neurons.

RGS11 GPR179

1.55e-044178226961947
Pubmed

Epsin-mediated degradation of IP3R1 fuels atherosclerosis.

ITPR1 EPN1

1.55e-044178232770009
Pubmed

Theileria-induced constitutive IKK activation is independent of functional Hsp90.

IKBKB HSP90AA1

1.55e-044178216938294
Pubmed

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

IRS1 IKBKB

1.55e-044178212351658
Pubmed

Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.

KDM3B ITPR1 INF2 KDM4B

1.60e-0453178436265442
Pubmed

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

RBMS2 IRS1 CMIP

1.64e-0421178322479202
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SMG1 HECW1 KDM3B TNRC6B MACF1 TLN2 KDM4B

1.69e-04225178712168954
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DHX40 MAST2 KHDRBS1 FAM120C NOM1 MACF1 PLCH1

2.15e-04234178736243803
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SHROOM3 CLASP1 CHD1L RXRB KHDRBS1 FAM120C RBMX MACF1 TLN2 HSP90AA1 HDLBP

2.21e-045821781120467437
Pubmed

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.

SMG1 CNOT11 TNRC6B RBMX HDLBP

2.31e-04107178530995489
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

ATG16L1 COX5B MKRN2 WDR3 KHDRBS1 RBMX ATG9A HECTD1 SLC27A4

2.35e-04400178935013556
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SHROOM3 PDE4D NUMBL BCAS3 HECTD4 TNRC6B CHD1L TSC22D1 CMIP DPP9 INF2 FAM120C KIAA1217 RBM6 MACF1 QSER1 HECTD1 KDM4B CPNE7

2.42e-0414891781928611215
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CLASP1 WFS1 RBMS1 TASP1 TNRC6B CHD1L TRIM14 WDR3 TRMU TKFC FAM120C NOM1 RBMX SEC61B BOP1 TAF15 CPNE7 HDLBP

2.53e-0413711781836244648
Pubmed

Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.

CLASP1 MACF1

2.58e-045178217113391
Pubmed

Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression.

TERF2 IKBKB

2.58e-045178220622870
Pubmed

TfR1 interacts with the IKK complex and is involved in IKK-NF-κB signalling.

IKBKB HSP90AA1

2.58e-045178223016877
Pubmed

Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes.

IRS1 IFT88

2.58e-045178219596798
Pubmed

Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling.

IRS1 KHDRBS1

2.58e-045178211604231
Pubmed

GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes.

RGS11 GPR179

2.58e-045178222689652
Pubmed

Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway.

IKBKB HECTD1

2.58e-045178232555320
Pubmed

Linkage map of nine loci defined by polymorphic DNA markers assigned to rat chromosome 13.

F5 ATP1A2

2.58e-04517828288230
Pubmed

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90.

IKBKB HSP90AA1

2.58e-045178211864612
Pubmed

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.

ITPR1 ATP1A2

2.58e-045178216292983
Pubmed

Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation.

ATG16L1 IRS1

2.58e-045178231515271
Pubmed

Pro-inflammatory self-reactive T cells are found within murine TCR-αβ(+) CD4(-) CD8(-) PD-1(+) cells.

PDCD1 AIRE

2.58e-045178227060346
InteractionYWHAH interactions

SLAIN2 ATG16L1 SHROOM3 CLASP1 NUMBL KIF26B BCAS3 SPEG HECTD4 KDM3B KLC2 IRS1 MAST2 CIC RUSC2 NHSL1 HAUS8 FRMD4A KANK1 GRID2IP RNPEP KIAA1217 MACF1 ATG9A USP54 PLCH1 HECTD1 HSP90AA1

2.66e-07110217428int:YWHAH
InteractionYWHAB interactions

SLAIN2 ATG16L1 SHROOM3 CLASP1 NUMBL KIF26B SPEG HECTD4 KLC2 IRS1 MAST2 CIC RUSC2 NHSL1 KANK1 TKFC GRID2IP RBMX MACF1 ATG9A USP54 IKBKB PLCH1 HECTD1 HSP90AA1

2.16e-06101417425int:YWHAB
InteractionTOP3B interactions

ARHGEF19 CNOT11 SHROOM3 BCAS3 RBMS1 SPEG MKRN2 HECTD4 TASP1 KDM3B PEX6 TNRC6B PAPLN IRS1 MAST2 CIC PPP1R26 NHSL1 TKFC INF2 FAM120C CASKIN1 ZNRF1 TLN2 TAF15 ATG9A SLC45A1 HECTD1 IQCE HDLBP TJP3

3.07e-06147017431int:TOP3B
InteractionYWHAG interactions

SLAIN2 ATG16L1 SHROOM3 CLASP1 NUMBL KIF26B BCAS3 SPEG HECTD4 KDM3B KLC2 IRS1 MAST2 CIC RUSC2 NHSL1 HAUS8 FRMD4A KANK1 GRID2IP CSNK1G3 MACF1 TAF15 ATG9A USP54 PLCH1 HECTD1 HSP90AA1

3.09e-06124817428int:YWHAG
InteractionTRIM27 interactions

SLAIN2 TCEA2 ATG16L1 ZNF219 DHX40 COX5B TNRC6B PLEKHN1 RXRB KRT76 PIAS3 GAS2L2 TRIM55 IKBKB IQCE CPNE7

1.04e-0551417416int:TRIM27
InteractionFUBP3 interactions

SUMF2 ARHGEF19 CNOT11 RBMS1 RBMS2 MKRN2 TNRC6B FAM120C RBM6 USP54 IKBKB HDLBP

1.10e-0529717412int:FUBP3
InteractionTPX2 interactions

ARHGEF19 RBMXL1 CIC HMGA2 CSNK1G3 RP9 ATP1A2 IKBKB HECTD1 HDLBP

1.16e-0520417410int:TPX2
InteractionRUSC2 interactions

ATG16L1 KLC2 RUSC2 KHDRBS1 ATG9A

1.80e-05381745int:RUSC2
InteractionMEX3B interactions

SMG1 CNOT11 RBMS1 RBMS2 MKRN2 TNRC6B RUNX3 RUSC2 USP54 HDLBP

2.40e-0522217410int:MEX3B
InteractionPRRC2A interactions

SMG1 ATG16L1 CNOT11 RBMS1 RBMS2 MKRN2 TNRC6B IFT88 FAM120C RBMX USP54 HECTD1 HDLBP

3.49e-0538917413int:PRRC2A
InteractionCDC5L interactions

SHROOM3 ERCC5 CLASP1 DHX40 RBMS2 MKRN2 CHD1L CIC RXRB KHDRBS1 FAM120C RBMX TRIM55 RBM6 MACF1 TLN2 TAF15 HECTD1 HSP90AA1 HDLBP

5.13e-0585517420int:CDC5L
InteractionYWHAZ interactions

CCDC134 ATG16L1 SHROOM3 PDE4D CLASP1 NUMBL KIF26B SPEG HECTD4 KLC2 IRS1 MAST2 CIC ITPR1 RUSC2 NHSL1 KANK1 KRT24 NFATC4 CSNK1G3 MACF1 ATG9A USP54 PLCH1 HECTD1 HSP90AA1

6.67e-05131917426int:YWHAZ
InteractionFMR1 interactions

SMG1 ATG16L1 ZNF219 CLASP1 NUMBL RBMS1 MKRN2 ZMYND8 TNRC6B FAM120C KIAA1217 CASKIN1 MACF1 HECTD1 HDLBP

6.68e-0553617415int:FMR1
GeneFamilyRNA binding motif containing

CELF6 RBMXL1 RBMS1 RBMS2 RBMX RBM6 TAF15

4.27e-042131157725
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 PDE4D BCAS3 TNRC6B KANK1 CMIP RBM6 MACF1

1.09e-061921788e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLASP1 ITPR1 TCF24 KLHL3 FRMD4A TMTC1 KANK1 SLC2A12

1.23e-061951788a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellmoderate-Lymphoid-Treg|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SMG1 PDCD1 ACAP1 PDE4D DUSP1 TNRC6B RUNX3 MACF1

1.27e-0619617889152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NUMBL ADAMTS1 CIART WFS1 IRS1 TMTC1 CASKIN1 TLN2

1.43e-061991788a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELF6 GPRIN1 AMER2 PTPRN CASKIN1 CCDC74A ASIC4

6.56e-061741787742c73c9e090848b464323cb17579b86658c6792
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELF6 GPRIN1 AMER2 PTPRN CASKIN1 CCDC74A ASIC4

6.56e-0617417877fed9722e64c60843092f2ba71256e3043011ef6
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 ADAMTS1 PAPLN DIO3 MACF1 TLN2 ATP1A2

6.81e-0617517871799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 ITPR1 TCF24 KLHL3 TSC22D1 KANK1 ALPK3

8.49e-061811787e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SMG1 PDE4D RBMS1 DUSP1 TNRC6B RUNX3 ASIC4

9.45e-061841787cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 IGSF1 ATP1A2

9.45e-06184178722c18964818fc9c8f18051f836d718937b0d8d12
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

KIF26B HIF3A TRIM14 IFIT3 ALPK3 ATG9A HSP90AA1

9.45e-0618417872e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

KIF26B ZMYND8 HECTD4 KANK1 CMIP HMGA2 TLN2

1.01e-051861787de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

KIF26B ZMYND8 HECTD4 KANK1 CMIP HMGA2 TLN2

1.01e-0518617870b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellIPF-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

COL12A1 WFS1 RRAS INF2 SUSD2 HACD1 SLC27A4

1.01e-051861787d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 RBMS1 RRAS TSC22D1 TMTC1 NFATC4 ATP1A2

1.05e-051871787d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 RBMS1 RRAS TSC22D1 TMTC1 NFATC4 ATP1A2

1.05e-051871787d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 RBMS1 RRAS TSC22D1 TMTC1 NFATC4 ATP1A2

1.05e-051871787ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHROOM3 COL12A1 WFS1 NHSL1 SUSD2 SGCE HSP90AA1

1.09e-051881787e9cef856a96a97afac5ecafe2ee91eff0d731e01
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHROOM3 HIF3A NHSL1 KANK1 KIAA1217 USP54 PLCH1

1.16e-0519017878aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CELF6 GPRIN1 SLC12A5 CMIP PTPRN SLC45A1 HSP90AA1

1.29e-051931787b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|(2)_5-FU / Stress and Cell class

SHROOM3 RRAS TSC22D1 SUSD2 TLN2 SGCE HACD1

1.42e-051961787cc0a172de71d9a1a882c9e78652dae70e007d012
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 SPEG HIF3A ALPK3 IQCJ-SCHIP1 ATP1A2 HACD1

1.47e-051971787ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellASK452-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

COL12A1 WFS1 RBMS1 DUSP1 IFIT3 SUSD2 SGCE

1.57e-05199178748cafe44951908d03f3c6f3e185e9cbb86fb5b3b
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

SLAIN2 SHROOM3 TNRC6B IRS1 TRIM14 KHDRBS1 RLIM

1.57e-051991787c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HECTD4 KLC2 GPRIN1 SLC12A5 CMIP PTPRN SLC45A1

1.57e-051991787f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WFS1 PAPLN HIF3A MACF1 ATP1A2 PLCH1 SLC2A12

1.62e-052001787d0812817ef99608994193787a62d39adeb2070ca
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WFS1 PAPLN HIF3A MACF1 ATP1A2 PLCH1 SLC2A12

1.62e-052001787cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDHR3 PEX6 POU4F2 RXRB INF2 SLC27A4

4.06e-051571786ffb8dd381e6b9adc5283fb49586e8bd63773c8d6
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDHR3 PEX6 POU4F2 RXRB INF2 SLC27A4

4.06e-051571786c488ab1d6c6c7e5c2f4426805d1366b44711a031
ToppCellfacs-Brain_Myeloid-Cerebellum_|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCD1 COL12A1 DHX58 RBMS1 IFIT3 INF2

4.67e-0516117865c762609531a7c5505aa5637abf8e0311568d7fd
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCD1 COL12A1 DHX58 RBMS1 IFIT3 INF2

4.67e-051611786b14a83ad07a7acb07c766aa862b527698976b6fc
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCD1 COL12A1 DHX58 RBMS1 IFIT3 INF2

4.67e-051611786c5d9d47dcedfbb1ac77f4afaf860ae4d9f26fd3f
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDCD1 COL12A1 DHX58 RBMS1 IFIT3 INF2

4.67e-05161178626c0d876339bfd34d9a43af5b9fb08f50526f2c9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

ST6GALNAC1 SHROOM3 PDE4D HID1 KIAA1217 USP54

5.00e-051631786e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

6.74e-05172178655fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 COL12A1 WFS1 SH3RF2 SUSD2 IGSF1

6.74e-0517217860be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 TCF24 KLHL3 TSC22D1 KANK1 ALPK3

6.96e-0517317864bc6d93716f093b460c8b047199db8cab5fea720
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLASP1 PLEKHG4 ZNF180 KLC2 SUSD2 ATG9A

7.19e-051741786a1f745962a104c6f4b86b7e482da8755384c773a
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 F5 RITA1 ATG9A USP54 TACC3

7.19e-051741786c58328c2f262506a4518f49f148e29874faf9171
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE4D ADAMTS1 RGS11 IRS1 NFATC4 SLC45A1

7.90e-051771786e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CNOT11 NUMBL DHX40 RUNX3 PPP1R26 ZNRF1

8.40e-051791786163f5430d72ea0c1b239ea5d21e53be536636d3d
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CNOT11 NUMBL DHX40 RUNX3 PPP1R26 ZNRF1

8.40e-0517917860624dd537a68736f4d7b8b4de2c56168ed0e60a9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

8.93e-0518117860c3f469bed108994ed696230e3c30343f7a301d3
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PDCD1 HECTD4 PLEKHN1 TKFC ZNF792 SUSD2

9.21e-05182178621744c9c792e57d5d41b25986f419b2358c7057b
ToppCellNS-critical-d_0-4-Lymphoid-Treg|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDCD1 ACAP1 PDE4D RUNX3 RBM6 CPNE7

9.49e-051831786f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC25A41 CCDC74B COL12A1 ADAMTS1 RUSC2 NFATC4

1.01e-0418517869faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG ITPR1 FRMD4A KANK1 ATP1A2 HACD1

1.04e-0418617864780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 PDE4D KIF26B CDHR3 KANK1 TLN2

1.04e-041861786b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.07e-041871786dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHROOM3 DUSP1 SUSD2 KIAA1217 IQCJ-SCHIP1 USP54

1.07e-0418717864ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.07e-0418717864d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.07e-041871786ae90c263f80c36a410150d499e268d198944a3d9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.07e-0418717862b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.07e-0418717865d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.07e-0418717865c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.07e-04187178693c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

COL12A1 WFS1 RRAS INF2 SH3RF2 SUSD2

1.07e-0418717863a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

SHROOM3 PDE4D TASP1 ITPR1 TSC22D1 MACF1

1.10e-04188178634e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLASP1 ITPR1 TCF24 KLHL3 TSC22D1 KANK1

1.10e-041881786bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

SHROOM3 PDE4D KANK1 KIAA1217 USP54 PLCH1

1.10e-041881786c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLASP1 ITPR1 TCF24 KLHL3 TSC22D1 KANK1

1.10e-041881786eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PDE4D ZMYND8 ITPR1 FRMD4A KIAA1217 PLCH1

1.10e-041881786b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A CUEDC1 NHSL1 KANK1 ATP1A2

1.13e-041891786784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

SHROOM3 PDE4D TASP1 ITPR1 TSC22D1 MACF1

1.13e-0418917866b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D HECW1 CDHR3 PAPLN KANK1 IQCJ-SCHIP1

1.13e-04189178628b502611829e4a24caff2562545c7db97686099
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HECW1 KIF26B SPEG IRS1 IGSF1 ATP1A2

1.13e-0418917860abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A CUEDC1 NHSL1 KANK1 ATP1A2

1.13e-04189178637ecbd73408d462b47d7e5611f203143e08a2689
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.17e-0419017865c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.17e-0419017863a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D CDHR3 PAPLN KANK1 CMIP IQCJ-SCHIP1

1.17e-041901786989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WFS1 ZMYND8 CXXC1 ITPR1 KLHL3 ATG9A

1.17e-04190178663018acb7ad80415e861643162abdc2e55968ee4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.17e-0419017862de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.17e-041901786b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.17e-0419017861c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS1 SPEG IRS1 ITPR1 KANK1 ATP1A2

1.20e-0419117867853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D KIF26B CDHR3 PAPLN KANK1 IQCJ-SCHIP1

1.20e-0419117861cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHROOM3 NHSL1 KANK1 KIAA1217 USP54 PLCH1

1.20e-041911786ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 PDE4D KANK1 KIAA1217 USP54 PLCH1

1.20e-041911786e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SHROOM3 PDE4D KANK1 SUSD2 KIAA1217 USP54

1.23e-0419217861bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

SHROOM3 PDE4D KANK1 KIAA1217 USP54 PLCH1

1.23e-041921786499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL12A1 HECW1 KIF26B IRS1 HMGA2 TLN2

1.23e-04192178667e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.23e-041921786f7e4509003d71f805b9d4587098e90d2897b6739
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 HIF3A ITPR1 TMTC1 KIAA1217 TLN2

1.23e-0419217866c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.23e-04192178643beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCellHealthy_Control-Lymphoid-T-CD8_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PDCD1 ACAP1 PDE4D RUNX3 ZNRF1 CPNE7

1.23e-04192178636b6ea21b0b1342f2dcac4dcaf359b6c772203f7
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SHROOM3 PDE4D KANK1 KIAA1217 USP54 PLCH1

1.23e-041921786efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 PDE4D NPAP1 TRIM55 HECTD1 HACD1

1.23e-0419217862510f22197502f60fd266b7f42eff040f25b8ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 PDE4D NPAP1 TRIM55 HECTD1 HACD1

1.23e-041921786e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.23e-041921786705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.27e-041931786b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL12A1 ADAMTS1 KIF26B SPEG IGSF1 ATP1A2

1.27e-041931786000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN HIF3A NHSL1 KANK1 NFATC4 ATP1A2

1.27e-04193178640edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell15-Trachea-Epithelial-Basal_cell|Trachea / Age, Tissue, Lineage and Cell class

DUSP1 HIF3A PLEKHN1 ZNF750 TSC22D1 HMGA2

1.31e-04194178667edcbb9ed1a01dd06b6f17621c54aa58df74c69
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SHROOM3 PDE4D CDHR3 KIAA1217 USP54 PLCH1

1.34e-041951786fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SHROOM3 PDE4D CDHR3 KIAA1217 USP54 PLCH1

1.34e-041951786eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

SHROOM3 KANK1 SUSD2 KIAA1217 USP54 PLCH1

1.34e-0419517861798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

SHROOM3 RRAS SUSD2 TLN2 SGCE HACD1

1.42e-041971786434ae0231972acba12d06279908cf407e70511ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RBMS1 RBMS2 HIF3A NHSL1 TMTC1 EFNB1

1.46e-04198178692416e65a0dc1a4bf931833407620ea05d362f56
ToppCellCOVID-19_Severe|World / Disease Group and Platelet Clusters

TMEM219 COX5B RRAS SEC61B MACF1 HSP90AA1

1.46e-041981786aad65981cfc181d3abab24c75b19f6542818cf2c
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM3 PDE4D CLASP1 BCAS3 NHSL1 KANK1

1.46e-0419817861996373bdccc55aac347d349bd22f6aad6d0c668
Diseasehepatitis (is_marker_for)

PDCD1 F5

3.38e-0521722DOID:2237 (is_marker_for)
Diseasereticulocyte count

CLASP1 BCAS3 RBMS1 SOWAHD HECTD4 TNRC6B IRS1 RUNX3 MAST2 SLC12A5 PTPRN ZNF792 TLN2 TAF15 SLC45A1 ZNF385C ASPRV1

1.39e-04104517217EFO_0007986
Diseasebreast cancer (is_implicated_in)

DUSP1 RUNX3 F5 SLC22A18 IKBKB KDM4B

2.57e-041501726DOID:1612 (is_implicated_in)
Diseaseportal hypertension (biomarker_via_orthology)

DUSP1 F5 HSP90AA1

2.76e-04221723DOID:10762 (biomarker_via_orthology)
Diseaseresponse to gemcitabine, response to antineoplastic agent

PDE4D ALPK3

4.99e-0461722GO_0036272, GO_0097327
Diseaseurea measurement

SHROOM3 BCAS3

1.47e-03101722EFO_0011005
Diseasestomach cancer (is_marker_for)

PDCD1 RUNX3 EFNB1 SGCE KDM4B

1.50e-031421725DOID:10534 (is_marker_for)
Diseaseneuroimaging measurement

SHROOM3 KIF26B TNRC6B PGM1 NHSL1 AMER2 HMGA2 RLIM MACF1 TLN2 IQCJ-SCHIP1 QSER1 TACC3 PLCH1 KDM4B

1.55e-03106917215EFO_0004346
Diseaseinsulin sensitivity measurement, response to polyunsaturated fatty acid supplementation

TNRC6B TLN2

1.79e-03111722EFO_0004471, EFO_0009131
Diseasetransient cerebral ischemia (biomarker_via_orthology)

PDE4D ADAMTS1 DUSP1 ITPR1 IKBKB

2.32e-031571725DOID:224 (biomarker_via_orthology)
Diseasehematocrit

SLAIN2 SHROOM3 NUMBL BCAS3 RBMS2 HECTD4 PEX6 TNRC6B HID1 MAST2 ITPR1 ABRAXAS2 KLHL3 FRMD4A

2.49e-03101117214EFO_0004348
Diseasecorpus callosum volume measurement

KIF26B ABRAXAS2 RBM6 IQCJ-SCHIP1

2.83e-031001724EFO_0010299
Diseasecorpus callosum posterior volume measurement

TNRC6B RBM6 IQCJ-SCHIP1

3.49e-03521723EFO_0010298
Diseasereticulocyte measurement

CLASP1 RBMS1 SOWAHD HECTD4 TNRC6B IRS1 RUNX3 TRMU ZNF792 RBM6 TLN2 SLC45A1 ZNF385C ASPRV1

3.58e-03105317214EFO_0010700
DiseaseSjogren's syndrome (implicated_via_orthology)

MUC19 AIRE

4.34e-03171722DOID:12894 (implicated_via_orthology)
Diseasecancer (implicated_via_orthology)

ACAP1 HIF3A KANK1 MACF1 HACD1 HSP90AA1

4.99e-032681726DOID:162 (implicated_via_orthology)
Diseasehemifacial microsomia

SHROOM3 FRMD4A

5.41e-03191722MONDO_0015398
Diseasecortical thickness

SHROOM3 COL12A1 TNRC6B MAST2 PGM1 ABRAXAS2 NHSL1 HMGA2 MACF1 IQCJ-SCHIP1 QSER1 TACC3 PLCH1 KDM4B

5.79e-03111317214EFO_0004840

Protein segments in the cluster

PeptideGeneStartEntry
PMAVSASHRGGTGTR

nan

111

Q8NBF4
AMVSGGGRNESSPDS

ZNF280A

151

P59817
PAAAAVGSSMSGEGR

ZNF385C

201

Q66K41
MAGSRGAGRTAAPSV

BOP1

1

Q14137
METSRSRGGGGAVSE

AMER2

1

Q8N7J2
PRMPSSGFAAEGRST

ABRAXAS2

281

Q15018
MASGEHSPGSGAARR

RNPEP

1

Q9H4A4
SPGSRLLATGGMDRR

ATG16L1

331

Q676U5
AVGEGGAMGSRRAPS

ALPK3

196

Q96L96
MDVTSSSGGGGDPRQ

CMIP

1

Q8IY22
MSSAGGDRLGRGKSA

BTBD11

191

A6QL63
SAATLGSGGMARGRE

ACAP1

386

Q15027
SMPGSSRPVSDRRGV

BCAS3

801

Q9H6U6
MSGAGVAAGTRPPSS

CCDC74A

1

Q96AQ1
MSGAGVAAGTRPPSS

CCDC74B

1

Q96LY2
AGAMAPGALGSLSSR

DMRTA2

421

Q96SC8
SSGRSGGFMRKITPT

CDAN1

816

Q8IWY9
PRLGFSTADSGVGMS

CELF6

16

Q96J87
AVAMSSGDVPGARGA

AIRE

191

O43918
TRPSAAAGGAVGTMA

MKRN2

56

Q9H000
MSRSAAASGGPRRPE

NUMBL

1

Q9Y6R0
TGVRGFARSMPTSGA

PGM1

326

P36871
SFATRRPEFMRGGGS

TAF15

316

Q92804
SSGTSRGVGFARMES

RBMS1

176

P29558
SGTSRGVGFARMEST

RBMS2

171

Q15434
VRSSSGMGGRAPVSR

RBMX

171

P38159
TLGGDDSGVSMNPAR

QSER1

1026

Q2KHR3
GPGRGSCAASRVLMT

RGS11

206

O94810
SDMGNAERAPGSRSF

ADAMTS1

16

Q9UHI8
RTAGSMPLGGRASLT

IQCE

61

Q6IPM2
FPGGIRGRAMALTSS

SLC2A12

491

Q8TD20
GFSGRSAVVSGSSRM

KRT76

16

Q01546
GSSRMSCVARSGGAG

KRT76

26

Q01546
SPGGSDTEITSGGMR

ARHGEF19

81

Q8IW93
LGSASGSVGRVAMSR

MMTAG2

121

Q9BU76
PFAGGDRSGSISGMA

CASKIN1

381

Q8WXD9
DRSGSISGMAGGRGS

CASKIN1

386

Q8WXD9
GLSEAVPGSASMSRS

FAM189A1

426

O60320
SRDGSRVSEGSPGMV

PTPRN

216

Q16849
VIGRPRGMSASSVGS

KRT12

26

Q99456
RGPVSGSPDSMNASR

IKBKB

666

O14920
MASRAGPRAAGTDGS

JAGN1

1

Q8N5M9
SGTAGESMGAPSRSP

GPR179

1116

Q6PRD1
GGSGSSSMSRGEMSL

ITPR1

1786

Q14643
GQRRAGMATESPSDS

TRMU

396

O75648
GSQGASGPAATMLRS

DIO3

16

P55073
TAAATPDGMRRSGSI

HECW1

861

Q76N89
GTMPRAGRSLGRSAG

KIF26B

1701

Q2KJY2
RASSSLDSMPGPAGR

DCAF12L2

386

Q5VW00
VLEGGAAGSMSPSRV

NHSL1

1266

Q5SYE7
GMGTSSPARRGSADG

PDCD1

256

Q15116
TSGQSARMTGASGPS

MUC19

2886

Q7Z5P9
ARMTGASGPSVGVTG

MUC19

2891

Q7Z5P9
GATASLGGSAMTRGR

MUC19

6696

Q7Z5P9
ATTSPGASGMTGVRT

MUC19

7591

Q7Z5P9
MEAEGSSAPARAGSG

PDE4D

1

Q08499
SRGRSGDSGGVMDRV

PEX6

811

Q13608
AAMRSMASGGGVPTD

COX5B

26

P10606
MTSLFRRSSSGSGGG

CUEDC1

1

Q9NWM3
RPRLASFGGMGTTSS

KANK1

181

Q14678
TSGGPSLSAMGNGRS

KDM3B

711

Q7LBC6
TGPEDGAASSGAGRM

KDM4B

571

O94953
GAASSGAGRMETKAR

KDM4B

576

O94953
MGSRDLVSGDSRSGS

KRT24

471

Q2M2I5
SSLPSRAGGMGSGLE

ASIC4

211

Q96FT7
SSEGRPFRLGTGANM

HECTD4

1551

Q9Y4D8
VRASSDGEGTMSRPA

IRS1

326

P35568
DGEGTMSRPASVDGS

IRS1

331

P35568
MADSSGRGAGKPATG

HAUS8

1

Q9BT25
TRGTGSSSSGVLMVG

CSNK1G3

26

Q9Y6M4
SVLNSSPAMRGGARG

MDS2

51

Q8NDY4
RGRGDTDGGSKAASM

INF2

991

Q27J81
EGASQGMTPFRSRGR

MACF1

7206

Q9UPN3
RSSRDMAGGAGPRSE

KLC2

506

Q9H0B6
GSAGGTVSELMPRSV

PCDHA13

571

Q9Y5I0
ASSGSMPNLAARGGA

FRMD4A

796

Q9P2Q2
MGRGAGREYSPAATT

ATP1A2

1

P50993
ATGSPSVRRMKGGSA

CCDC71

261

Q8IV32
TGVGAMLARGSASPH

CXXC1

126

Q9P0U4
LLSRMAAAGGTVSGP

HECTD1

236

Q9ULT8
GAFPITNISGTSMGR

IGSF1

1021

Q8N6C5
ASSIGRPMTGAIQDG

IFT88

76

Q13099
AGEGLRSSGMVSPLA

GRID2IP

1196

A4D2P6
SRMGREGEGTHSSLG

BRME1

316

Q0VDD7
DGGRTSDTGRTLMRG

COL12A1

1921

Q99715
AGSPAMAVLDRGTST

DUSP1

321

P28562
MATTGTPTADRGDAA

DPP9

1

Q86TI2
TMPSGVGSGSRFLQD

CDHR3

386

Q6ZTQ4
ERGAGTGASREMAPF

GAS2L2

346

Q8NHY3
GRAHSTMTGSGVDAR

ATG9A

666

Q7Z3C6
MSAGSERGAAATPGG

CPNE7

1

Q9UBL6
MGRLTEAAAAGSGSR

HACD1

1

B0YJ81
MERAGATSRGGQAPG

CHD1L

1

Q86WJ1
SAGTRMGPASCGGRS

TMEM132E-DT

11

A2RUQ5
MATQAPGSRGSLGDS

EFNB1

191

P98172
SRSSRGRGSFGMQVV

FAM120C

971

Q9NX05
GSEEMGQGAVSSSPR

IFIT3

466

O14879
TVTTLSGDMGPRAGF

DHX58

76

Q96C10
RSSGSSPAMETRGRG

MAST2

991

Q6P0Q8
MSGVRGSLAEAVGSP

EPN1

441

Q9Y6I3
MSRSSGRSGSMDPSG

KHDRBS1

11

Q07666
MSTRRSGAGVGVLSG

KLHL3

476

Q9UH77
MSARGEGAGQPSTSA

HMGA2

1

P52926
MAATEPSTGDGGDTR

DCAF8L1

41

A6NGE4
AGGSFTVRTDTGEPM

HSP90AA1

166

P07900
MAGTSAPGSKRRSEP

ATRIP

1

Q8WXE1
SGRSATEMSGRGSVL

FAM90A20P

166

A6NIJ5
GMESRHRSPSGAGEG

GPRIN1

66

Q7Z2K8
AMTAAAGSAGRAAVP

GALC

16

P54803
VGRTFCTMDGRGSPV

DHX40

636

Q8IX18
LSGGTGRRISLSDMP

ZMYND8

416

Q9ULU4
AGSSADGTRRGMGVD

SLC45A1

696

Q9Y2W3
GGPMTRSYRSTARTG

MENT

41

Q9BUN1
FPSVTGIMAGSNRSG

SLC12A5

431

Q9H2X9
ADGSSMPTSTPREGR

MUC17

1911

Q685J3
AGGMAVAGTATGPRT

GARIN3

266

Q8TC56
VAGSSSGGDRSPTRM

RUNX3

346

Q13761
ARGGGEGSMATRPSN

RUSC2

871

Q8N2Y8
SGRMATAPIRASASG

RTL9

1011

Q8NET4
RMRGPSVGASGRTSK

RBM6

1086

P78332
RAQPGTMSNGTETRG

SUSD2

486

Q9UGT4
GRFLMGTNSPDSRDG

SUMF2

36

Q8NBJ7
EVAAGQMASSSRSGP

TACC3

321

Q9Y6A5
MSSRPGREDVGAAGA

RP9

1

Q8TA86
GNREDSARMSAGLPG

PLEKHN1

26

Q494U1
APSGLVRSSSGMGGR

RBMXL1

166

Q96E39
VRSSSGMGGRAPLSR

RBMXL1

171

Q96E39
ATLTRPAGTTAMRSG

SLAIN2

521

Q9P270
AGKMAAPRRGRGSST

TMEM80

71

Q96HE8
GRHLSQDTGSPSGMR

F5

891

P12259
GLRMFPETRGTTGCA

NFATC4

761

Q14934
ASGMATLPGTRDVQG

PLEKHG4

191

Q58EX7
SGSSGGGGSEAMRRA

POU4F2

76

Q12837
RGDPSASSPMAGARK

HIF3A

556

Q9Y2N7
TGSQEGTSMEGSRPA

HID1

591

Q8IV36
MSRRAPGSRLSSGGG

SMG1

1

Q96Q15
TGGPGAEEMRINSST

ERCC5

411

P28715
MSEGDAPTPFSRGSR

KIAA1217

151

Q5T5P2
TLSPRGQDAGMASGR

ST6GALNAC1

136

Q9NSC7
GISGRERSGSMDNTS

SHROOM3

276

Q8TF72
ERSGSMDNTSARGGL

SHROOM3

281

Q8TF72
MAGAVSRTGTAPLDR

SLC25A41

101

Q8N5S1
LSMGSRESVEGSGRS

SAMD14

216

Q8IZD0
MAASRSAGEAGPGGS

NOM1

1

Q5C9Z4
GTARGPGDTRMSQGQ

PPP1R26

651

Q5T8A7
AMFPRRGSGSGSASA

TSC22D1

26

Q15714
FPGTLMHSAAGSGRR

SOWAHD

56

A6NJG2
RSGGGGGRSATTAMP

IQCJ-SCHIP1

206

B3KU38
GFRIATGMPGTGDST

NPAP1

981

Q9NZP6
TGQGRGTRRMSPATT

SGCE

16

O43556
GSRSEGASFGAPRMA

RITA1

116

Q96K30
GRSPGRMSALGRSSV

SLC22A18

11

Q96BI1
DGMGDSGRDSRSPDS

RXRB

71

P28702
SGMGATGTLRTSLDP

CCDC134

16

Q9H6E4
ESSRMAGSGARSEEG

ASPRV1

81

Q53RT3
ASPMAGSGAKRSRDG

CIART

86

Q8N365
RERSMSETGTAAAPG

CIC

296

Q96RK0
PNDTAGARTEMGTGS

CIC

701

Q96RK0
GMGTTRRLGSSTLGS

CLASP1

271

Q7Z460
MPGGGASAASGRLLT

CNOT11

1

Q9UKZ1
RSPAMGTLGGDFLSS

PIAS3

496

Q9Y6X2
MDRGRPAGSPLSASA

TCF24

1

Q7RTU0
AGTGSRGSSRRGSMN

PITPNM1

581

O00562
EGSKMSPRAGSAATG

ZNF750

396

Q32MQ0
SFSRVMIGSPRGGAS

ZBTB5

516

O15062
GGTTMASGGRFRCPS

TRIM55

66

Q9BYV6
MVVTTSARGGGGDRT

TMTC1

1

Q8IUR5
GGSSARGSPVLAMRR

SPEG

2441

Q15772
TRSAGRTTSAGTGGM

SEC61B

41

P60468
GGDSTGGMPRSRAVA

PAPLN

686

O95428
VPGTEGRAGMAAVAS

SLC27A4

541

Q6P1M0
NMERAESRSGRGGSG

RLIM

436

Q9NVW2
LGMSSPRGGRTTSNA

PLCH1

1056

Q4KWH8
SAAAASGSDTAGMRG

nan

66

Q8IYB0
SGSDTAGMRGLGKAP

nan

71

Q8IYB0
MAGAATGSRTPGRSE

TRIM14

1

Q14142
MRACAGSTREAGSGA

ZNF180

1

Q9UJW8
ISGGRDRPGGSMVVS

TJP3

26

O95049
TSAMARGAYGRPGSD

ZNF792

81

Q3KQV3
MRSGSSGPETFNVGS

TLN2

456

Q9Y4G6
SEEGAGNATLSPRMG

TMEM219

161

Q86XT9
SSGRGGSFRRPGTMT

SH3RF2

81

Q8TEC5
GRGMPLPTSSRDASE

TCEA2

91

Q15560
GGVMVSFPRSGTQSD

HDLBP

831

Q00341
SMSLSPDQRGFVTGG

WDR3

501

Q9UNX4
MSSGAASGTGRGRPR

RRAS

1

P10301
PDSTAAGGSASKRMA

TKFC

361

Q3LXA3
GMSSGEGLPSRSSQV

TASP1

6

Q9H6P5
GARRSDTMAGGGGSS

TERF2

36

Q15554
GSGGTVAPATMGSAR

ZBTB22

176

O15209
RARSSGGMQATPATE

ZNF219

136

Q9P2Y4
GGAMGLRSRSVSSVA

ZNRF1

41

Q8ND25
MEPGGDHRSRSSGGR

ZFTA

1

C9JLR9
FGMGLGNTSRSTDAP

TNRC6B

396

Q9UPQ9
GRGSVQGMFAPRSST

USP54

11

Q70EL1
PLSQTGSADGMGRRL

USP54

1346

Q70EL1
MPFSSGADGSRSREE

WFS1

781

O76024
DGRPRGTSGMGARVS

KIAA1522

201

Q9P206