Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	acetylcholine receptor regulator activity	SPDYE1 SPDYE2 SPDYE2B SPDYE6	2.29e-06	27	70	4	GO:0030548
GeneOntologyMolecularFunction	neurotransmitter receptor regulator activity	SPDYE1 SPDYE2 SPDYE2B SPDYE6	2.66e-06	28	70	4	GO:0099602
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein serine/threonine kinase activity	SPDYE1 SPDYE2 SPDYE2B SPDYE6	1.38e-06	25	69	4	GO:0045737
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein kinase activity	SPDYE1 SPDYE2 SPDYE2B SPDYE6	2.21e-06	28	69	4	GO:1904031
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein serine/threonine kinase activity	CCNF SPDYE1 SPDYE2 SPDYE2B SPDYE6	1.75e-05	96	69	5	GO:0000079
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein kinase activity	CCNF SPDYE1 SPDYE2 SPDYE2B SPDYE6	2.13e-05	100	69	5	GO:1904029
GeneOntologyBiologicalProcess	cellular response to forskolin	CFTR HDAC8 CREB1	2.82e-05	18	69	3	GO:1904322
GeneOntologyBiologicalProcess	positive regulation of anion channel activity	TCAF1 CFTR	3.30e-05	3	69	2	GO:1901529
GeneOntologyBiologicalProcess	positive regulation of anion transmembrane transport	TCAF1 CFTR	3.30e-05	3	69	2	GO:1903961
GeneOntologyBiologicalProcess	response to forskolin	CFTR HDAC8 CREB1	3.34e-05	19	69	3	GO:1904321
GeneOntologyBiologicalProcess	positive regulation of monoatomic anion transport	TCAF1 CFTR	6.59e-05	4	69	2	GO:1903793
GeneOntologyBiologicalProcess	regulation of anion channel activity	TCAF1 CFTR	1.64e-04	6	69	2	GO:0010359
GeneOntologyCellularComponent	ATF4-CREB1 transcription factor complex	CREB1 CREM	6.42e-05	4	69	2	GO:1990589
Domain	Spy1	SPDYE1 SPDYE2 SPDYE21 SPDYE2B SPDYE6	2.90e-10	11	70	5	PF11357
Domain	Speedy	SPDYE1 SPDYE2 SPDYE21 SPDYE2B SPDYE6	2.90e-10	11	70	5	IPR020984
Domain	KID	CREB1 CREM	4.14e-05	3	70	2	PS50953
Domain	Coactivator_CBP_pKID	CREB1 CREM	4.14e-05	3	70	2	IPR003102
Domain	pKID	CREB1 CREM	4.14e-05	3	70	2	PF02173
Domain	Leuzip_CREB	CREB1 CREM	8.27e-05	4	70	2	IPR001630
Domain	bZIP_1	CREB1 CREM	7.19e-03	34	70	2	PF00170
Domain	TF_DNA-bd	CREB1 CREM	8.47e-03	37	70	2	IPR008917
Pubmed	Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.	SPDYE1 SPDYE2 SPDYE2B SPDYE6	1.99e-09	9	71	4	36272447
Pubmed	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.	SPDYE1 SPDYE2 SPDYE2B SPDYE6	1.12e-08	13	71	4	15611625
Pubmed	Characterization of a new family of cyclin-dependent kinase activators.	SPDYE1 SPDYE2 SPDYE2B SPDYE6	3.72e-08	17	71	4	15574121
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	DNAJB12 NBAS SCAP ATP13A1 SCD VPS4B TMEM30A CHD7 PRPF18 PDZRN3 ITPR2	2.75e-07	733	71	11	34672954
Pubmed	cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells.	SCD CREB1 CREM	6.79e-07	9	71	3	23637738
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	RPL23A TCAF1 IRS4 MAP7D3 SCD NOB1 AGK PRKDC NXF1	1.73e-06	547	71	9	37267103
Pubmed	Defining the membrane proteome of NK cells.	DNAJB12 NBAS RASAL3 MAP7D3 ATP13A1 SCD TMEM30A CHPF2 PRKDC LMBRD1 RPL18 ITPR2	4.00e-06	1168	71	12	19946888
Pubmed	The expanding family of CREB/CREM transcription factors that are involved with spermatogenesis.	CREB1 CREM	4.11e-06	2	71	2	11988318
Pubmed	MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo.	CIITA PRKDC	4.11e-06	2	71	2	16081800
Pubmed	Increased hippocampal neurogenesis and accelerated response to antidepressants in mice with specific deletion of CREB in the hippocampus: role of cAMP response-element modulator τ.	CREB1 CREM	4.11e-06	2	71	2	23966689
Pubmed	The role of cAMP response element-binding protein in estrogen negative feedback control of gonadotropin-releasing hormone neurons.	CREB1 CREM	4.11e-06	2	71	2	22895714
Pubmed	cAMP response element-binding protein regulates differentiation and survival of newborn neurons in the olfactory bulb.	CREB1 CREM	4.11e-06	2	71	2	16267218
Pubmed	Cyclic adenosine 5'-monophosphate response element binding protein plays a central role in mediating proliferation and differentiation downstream of the pre-TCR complex in developing thymocytes.	CREB1 CREM	4.11e-06	2	71	2	15265911
Pubmed	Cyclic AMP response element-binding protein is required for normal maternal nurturing behavior.	CREB1 CREM	4.11e-06	2	71	2	15893884
Pubmed	Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform.	CREB1 CREM	4.11e-06	2	71	2	8605879
Pubmed	Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity.	CREB1 CREM	4.11e-06	2	71	2	21998402
Pubmed	Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells.	CREB1 CREM	4.11e-06	2	71	2	20920259
Pubmed	Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test.	CREB1 CREM	4.11e-06	2	71	2	29044198
Pubmed	An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription.	CREB1 CREM	4.11e-06	2	71	2	7809053
Pubmed	Identification of human myometrial target genes of the cAMP pathway: the role of cAMP-response element binding (CREB) and modulator (CREMalpha and CREMtau2alpha) proteins.	CREB1 CREM	4.11e-06	2	71	2	15691874
Pubmed	Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript.	CREB1 CREM	4.11e-06	2	71	2	7916662
Pubmed	Cyclic AMP response element binding protein CREB and modulator protein CREM are products of distinct genes.	CREB1 CREM	4.11e-06	2	71	2	1461747
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	RPL23A DNAJB12 TCAF1 IRS4 GCAT SCD VPS4B NOB1 AGK PRKDC NXF1 RPL18	8.42e-06	1257	71	12	37317656
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	RPL23A DNAJB12 NBAS ATP13A1 SCD RPL18 ITPR2	1.18e-05	375	71	7	32788342
Pubmed	Evolution of the Cdk-activator Speedy/RINGO in vertebrates.	SPDYE2 SPDYE6	1.23e-05	3	71	2	22763696
Pubmed	Prostaglandin E2 modulates IL-8 expression through formation of a multiprotein enhanceosome in human colonic epithelial cells.	CREB1 CREM	1.23e-05	3	71	2	22531917
Pubmed	Transcriptional regulation by cyclic AMP is essential for development, reproduction and survival: lessons from the transgenic mice.	CREB1 CREM	1.23e-05	3	71	2	9916858
Pubmed	Possible influence of CREB1, CREBBP and CREM variants on diagnosis and treatment outcome in patients with schizophrenia.	CREB1 CREM	1.23e-05	3	71	2	22198373
Pubmed	Critical role of transcription factor cyclic AMP response element modulator in beta1-adrenoceptor-mediated cardiac dysfunction.	CREB1 CREM	1.23e-05	3	71	2	19103994
Pubmed	Regulation of human MC2-R gene expression by CREB, CREM, and ICER in the adrenocortical cell line Y1.	CREB1 CREM	1.23e-05	3	71	2	17712720
Pubmed	SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability.	CREB1 CREM	1.23e-05	3	71	2	15880109
Pubmed	Family members CREB and CREM control thyrotropin-releasing hormone (TRH) expression in the hypothalamus.	CREB1 CREM	1.23e-05	3	71	2	23000398
Pubmed	PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation.	CREB1 CREM	1.23e-05	3	71	2	14754893
Pubmed	Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5'-untranslated region and an important role for cAMP-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes.	CIITA CREB1	1.23e-05	3	71	2	12391222
Pubmed	Case-control association study of 14 variants of CREB1, CREBBP and CREM on diagnosis and treatment outcome in major depressive disorder and bipolar disorder.	CREB1 CREM	1.23e-05	3	71	2	22386572
Pubmed	A negative feedback loop of ICER and NF-κB regulates TLR signaling in innate immune responses.	CREB1 CREM	1.23e-05	3	71	2	28009352
Pubmed	NSSR1 is regulated in testes development and cryptorchidism and promotes the exon 5-included splicing of CREB transcripts.	CREB1 CREM	1.23e-05	3	71	2	17427975
Pubmed	Survival of DA neurons is independent of CREM upregulation in absence of CREB.	CREB1 CREM	1.23e-05	3	71	2	16981198
Pubmed	Asymmetry-defective oligodendrocyte progenitors are glioma precursors.	CSPG4 PRKDC	1.23e-05	3	71	2	21907924
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	RPL23A UTP15 ATP13A1 PRKDC VARS2 RPL18	1.54e-05	259	71	6	30404004
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	DNAJB12 IRS4 SCAP ATP13A1 SCD AGK TMEM30A VPS26A RPL18 ITPR2	2.30e-05	952	71	10	38569033
Pubmed	Inactivation of CREB mediated gene transcription by HDAC8 bound protein phosphatase.	HDAC8 CREB1	2.46e-05	4	71	2	19070599
Pubmed	Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine.	CREB1 CREM	2.46e-05	4	71	2	19001277
Pubmed	cAMP stringently regulates human cathelicidin antimicrobial peptide expression in the mucosal epithelial cells by activating cAMP-response element-binding protein, AP-1, and inducible cAMP early repressor.	CREB1 CREM	2.46e-05	4	71	2	19531482
Pubmed	Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate.	CREB1 CREM	2.46e-05	4	71	2	11354513
Pubmed	BDNF selectively regulates GABAA receptor transcription by activation of the JAK/STAT pathway.	CREB1 CREM	2.46e-05	4	71	2	18922788
Pubmed	EWSR1 Fusions With CREB Family Transcription Factors Define a Novel Myxoid Mesenchymal Tumor With Predilection for Intracranial Location.	CREB1 CREM	2.46e-05	4	71	2	28009602
Pubmed	Ca2+-dependent block of CREB-CBP transcription by repressor DREAM.	CREB1 CREM	2.46e-05	4	71	2	12198160
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	DNAJB12 B3GNT9 ATP6V0A1 B4GALNT1 SCAP LOXL2 CSPG4 TMEM30A CHPF2 ITPR2 NXPE3	3.05e-05	1201	71	11	35696571
Pubmed	The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking.	IRS4 MAP7D3 CIITA PRKDC RPL18	3.20e-05	177	71	5	26485645
Pubmed	Disruption of CREB function in brain leads to neurodegeneration.	CREB1 CREM	4.09e-05	5	71	2	11967539
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RPL23A MAP7D3 UBP1 SCD POT1 CHD7 PRKDC CREB1 CREM NXF1 RPL18	5.99e-05	1294	71	11	30804502
Pubmed	Activating transcription factor 1 and CREB are important for cell survival during early mouse development.	CREB1 CREM	6.13e-05	6	71	2	11865068
Pubmed	A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM.	CREB1 CREM	6.13e-05	6	71	2	11046156
Pubmed	Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.	RPL23A ATP6V0A1 VRTN TWNK CHD7 RPL18	6.15e-05	332	71	6	30595499
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	NBAS SCAP ATP13A1 UBP1 SCD TMEM30A VARS2 CREB1 CREM NXF1 RPL18	7.50e-05	1327	71	11	32694731
Pubmed	Telomere protection by TPP1/POT1 requires tethering to TIN2.	POT1 PRKDC	8.57e-05	7	71	2	22099311
Pubmed	Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy.	ALKBH1 CFTR	8.57e-05	7	71	2	22872573
Pubmed	Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.	NBAS FKBP6	8.57e-05	7	71	2	26025256
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	RPL23A IRS4 PRKDC VARS2 RPL18	9.17e-05	221	71	5	29991511
Pubmed	A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.	WNT7B PRKDC	1.14e-04	8	71	2	29681511
Pubmed	The CREB/CREM transcription factors negatively regulate early synaptogenesis and spontaneous network activity.	CREB1 CREM	1.14e-04	8	71	2	19144833
Pubmed	Specific ablation of the transcription factor CREB in sympathetic neurons surprisingly protects against developmentally regulated apoptosis.	CREB1 CREM	1.14e-04	8	71	2	17376811
Pubmed	Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome.	SCAP SCD	1.14e-04	8	71	2	32516576
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	RPL23A IRS4 VPS4B AGK PRKDC VARS2 NXF1 RPL18	1.15e-04	725	71	8	27025967
Pubmed	Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.	DNAJB12 ATP6V0A1 ATP13A1 SCD CHPF2	1.22e-04	235	71	5	32614325
Pubmed	Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins.	CREB1 CREM	1.47e-04	9	71	2	15568017
Pubmed	Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3.	B4GALNT1 CREM	1.47e-04	9	71	2	18308723
Pubmed	Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB.	CREB1 CREM	1.47e-04	9	71	2	11988169
Pubmed	Characterization of gene expression in human trabecular meshwork using single-pass sequencing of 1060 clones.	CREM ITPR2	1.47e-04	9	71	2	11053263
Pubmed	Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.	CREB1 ITPR2	1.47e-04	9	71	2	25737585
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RPL23A MAP7D3 UTP15 AGK TWNK PRKDC NXF1 RPL18	1.57e-04	759	71	8	35915203
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	RPL23A IRS4 NOB1 PRKDC RPL18	1.72e-04	253	71	5	29911972
Pubmed	A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export.	RPL23A NOB1	1.83e-04	10	71	2	21048991
Pubmed	The mutation in Chd7 causes misexpression of Bmp4 and developmental defects in telencephalic midline.	WNT7B CHD7	1.83e-04	10	71	2	22658483
Pubmed	Protein Binder Toolbox for Studies of Solute Carrier Transporters.	DNAJB12 ATP6V0A1 TMEM30A	2.09e-04	56	71	3	38878854
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	RPL23A DNAJB12 NBAS IRS4 MAP7D3 UTP15 AGK TWNK VARS2 RPL18 ITPR2	2.14e-04	1496	71	11	32877691
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RPL23A MAP7D3 UTP15 NOB1 AGK PRKDC TACSTD2 NXF1 RPL18 ITPR2	2.29e-04	1257	71	10	36526897
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	RPL23A IRS4 ATP6V0A1 UTP15 SCD AGK RPL18	2.34e-04	604	71	7	37616343
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	RPL23A VPS4B TWNK CHD7 PRKDC RPL18 ITPR2	2.91e-04	626	71	7	33644029
Pubmed	Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.	IRS4 PRKDC	3.16e-04	13	71	2	29285303
Pubmed	The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.	CREB1 CREM	3.16e-04	13	71	2	25694434
Pubmed	GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo.	SCD WNT7B	3.16e-04	13	71	2	17164424
Pubmed	Regulation of neural migration by the CREB/CREM transcription factors and altered Dab1 levels in CREB/CREM mutants.	CREB1 CREM	3.16e-04	13	71	2	18786638
Pubmed	PARK2 promotes mitochondrial pathway of apoptosis and antimicrotubule drugs chemosensitivity via degradation of phospho-BCL-2.	RPL23A IRS4 AGK PRKDC RPL18	3.23e-04	290	71	5	32929329
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	RPL23A UTP15 SCD TMEM30A VARS2 RPL18	3.35e-04	454	71	6	33226137
Pubmed	Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.	AGK PRKDC VPS26A	3.56e-04	67	71	3	21875946
Pubmed	Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms.	CREB1 CREM	3.68e-04	14	71	2	27150575
Pubmed	Glycine prevents metabolic steatohepatitis in diabetic KK-Ay mice through modulation of hepatic innate immunity.	CIITA SCD	3.68e-04	14	71	2	27659424
Pubmed	The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.	IRS4 PRKDC	3.68e-04	14	71	2	21151955
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SCAP ATP13A1 WNT7B CSPG4 NOB1 TWNK PRKDC PLEKHG5 ITPR2	4.06e-04	1105	71	9	35748872
Pubmed	The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression.	RPL23A RPL18	4.24e-04	15	71	2	32299058
Pubmed	Mitochondrial DNA Maintenance Defects Overview	AGK TWNK	4.24e-04	15	71	2	29517884
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	RPL23A IRS4 UTP15 PRKDC NXF1 RPL18	4.65e-04	483	71	6	36912080
Pubmed	A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice.	WNT7B LMBRD1	4.84e-04	16	71	2	31680851
Pubmed	ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells.	RPL23A CREB1 RPL18	5.15e-04	76	71	3	36380368
Pubmed	The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue.	RPL23A AGK TWNK	5.77e-04	79	71	3	25921334
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	NBAS SCAP SCD VPS26A DOP1B ITPR2	5.81e-04	504	71	6	34432599
Pubmed	Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice.	CREB1 CREM	6.16e-04	18	71	2	16141355
Pubmed	Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins.	CREB1 CREM	6.16e-04	18	71	2	9858769
Interaction	ZBED2 interactions	CFTR POT1 NXF1	7.63e-07	6	69	3	int:ZBED2
Interaction	RYK interactions	CSPG4 CFTR AGK TMEM30A PRKDC VPS26A NXF1	8.01e-06	212	69	7	int:RYK
Interaction	VPS4B interactions	CCNF VPS4B CFTR VPS26A NXF1	1.28e-05	88	69	5	int:VPS4B
Interaction	RAB20 interactions	ALKBH1 UBP1 NXF1	3.58e-05	19	69	3	int:RAB20
Interaction	TRGV3 interactions	LOXL2 CSPG4 CHRD CHPF2	3.76e-05	55	69	4	int:TRGV3
Interaction	RRM2 interactions	CCNF MAP7D3 CFTR PRKDC CREB1	6.42e-05	123	69	5	int:RRM2
Interaction	IL5RA interactions	B4GALNT1 LOXL2 CSPG4 CHRD CHPF2	6.67e-05	124	69	5	int:IL5RA
Interaction	PRKACA interactions	CIITA CFTR HDAC8 AGK PRKDC CREB1 CREM NXF1 ITPR2	6.67e-05	519	69	9	int:PRKACA
Interaction	RNF5 interactions	CCNF DNAJB12 SCAP SCD CFTR	7.20e-05	126	69	5	int:RNF5
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE1 SPDYE2 SPDYE2B SPDYE6	1.11e-08	12	41	4	756
GeneFamily	DNA helicases	TWNK CHD7	6.68e-04	17	41	2	1167
GeneFamily	Beta 4-glycosyltransferases	B4GALNT1 CHPF2	6.68e-04	17	41	2	425
GeneFamily	Beta 3-glycosyltransferases	B3GNT9 CHPF2	1.34e-03	24	41	2	426
GeneFamily	Basic leucine zipper proteins	CREB1 CREM	5.52e-03	49	41	2	506
ToppCell	facs-Spleen\|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 CIITA SCD APOBEC3H RPL18	4.80e-07	183	71	6	d8e87234d2fc2059536ed456993ab0557d118361
ToppCell	facs-BAT-Fat-18m-Lymphocytic-B_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 CIITA SCD APOBEC3H LMBRD1	4.95e-07	184	71	6	fd72663bf990266da2fba70d4f2260f8d48067ee
ToppCell	facs-BAT-Fat-18m-Lymphocytic\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H CREM RPL18	4.95e-07	184	71	6	4928f0bc9d8659420680cbbc1900320b701a7cfd
ToppCell	droplet-Fat-Scat-18m-Lymphocytic-B_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A CIITA SCD APOBEC3H CREM RPL18	4.95e-07	184	71	6	d49d97fb02b8de259bf9bb23b71856cddbe0becc
ToppCell	facs-BAT-Fat-18m-Lymphocytic-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H CREM RPL18	4.95e-07	184	71	6	d06e6d1100aec95a30d571245c4992c5cb854ae5
ToppCell	droplet-Limb_Muscle-nan-3m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 CIITA SCD APOBEC3H	5.11e-07	185	71	6	a01d25a5642337cfcdef5fcd189b3150a5fad911
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-B_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 CIITA SCD APOBEC3H CREM	5.28e-07	186	71	6	d5d990d8b6ccd8ca8fe7d0d7dedbe2359ae7b582
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 CIITA SCD LMBRD1 RPL18	5.28e-07	186	71	6	664295cd508dc3894d55da7e9d9cd75bf1432f52
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 CIITA SCD LMBRD1 RPL18	5.28e-07	186	71	6	b30eb0c1673ca1ebc9b6248877d86fd6d6d14470
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 CIITA SCD APOBEC3H RPL18	6.35e-07	192	71	6	bf0819e99d7bf742c33afad2a0b66a60e1cfb1c2
ToppCell	facs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A1 CSPG4 TACSTD2 HAO2 DRC3	7.51e-06	169	71	5	daed9083ee05c220365200328c2c50047fe21efd
ToppCell	facs-Heart-RA-3m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 CIITA SCD APOBEC3H TACSTD2	8.41e-06	173	71	5	49030c2dd04b592655df1a667e2f90efb499e0a5
ToppCell	facs-Heart-RA-3m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 CIITA SCD APOBEC3H TACSTD2	8.41e-06	173	71	5	1cfbab6603f8baf8e238837bb72740c43a7dc0ec
ToppCell	droplet-Fat-Scat-18m-Lymphocytic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 APOBEC3H CREM RPL18	9.40e-06	177	71	5	872f05dca01e6d89a0b69d1a34840f09a2fa1948
ToppCell	droplet-Fat-Scat-18m-Lymphocytic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 APOBEC3H CREM RPL18	9.40e-06	177	71	5	76be975de7ebb2f8f7ea642244757a6dd44acd72
ToppCell	droplet-Lung-nan-21m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H NXPE3	9.66e-06	178	71	5	c973818aa6b79127267c95294c09c70ab3e2fd07
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 CIITA SCD APOBEC3H LMBRD1	9.66e-06	178	71	5	ba5a477257877f4a15a91c1762ffcc6f2e9f7357
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 CIITA SCD APOBEC3H LMBRD1	9.66e-06	178	71	5	5634c1fbc817758092af4feafff94d107412d89b
ToppCell	droplet-Thymus-nan-24m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A CIITA SCD APOBEC3H RPL18	9.66e-06	178	71	5	9c6cb39647d5a040ae325bc75148dfddbff7621e
ToppCell	droplet-Lung-nan-21m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H NXPE3	9.66e-06	178	71	5	ada794cb77e09faf80539616adeb32b38999f667
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A B4GALNT1 RASAL3 RPL18 NXPE3	1.08e-05	182	71	5	c1665cd9b28fec4bfe4e3981d7992d660f37b97f
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H RPL18	1.13e-05	184	71	5	9dc7c8c0b8a74e09df51f24f0151c494cd1ea6ad
ToppCell	droplet-Fat-Mat-18m-Lymphocytic-B_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A SCD APOBEC3H RPL18 NXPE3	1.16e-05	185	71	5	98bb853c495eb16c3663685a8e20755bd309b520
ToppCell	droplet-Spleen\|droplet / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A CIITA SCD APOBEC3H RPL18	1.16e-05	185	71	5	392c3130c79f7a938b73461c9dded803bb5c5785
ToppCell	facs-GAT-Fat-18m-Lymphocytic-B_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 SCD APOBEC3H RPL18 NXPE3	1.16e-05	185	71	5	1eba3b058e23a7d19024b4363dfeb522a8af313d
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	NBAS CIITA PRKDC DOP1B ITPR2	1.19e-05	186	71	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic-B_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A CIITA SCD RPL18 NXPE3	1.19e-05	186	71	5	0018a949f9f5bfc17f823601303f04dfd56c9a38
ToppCell	facs-BAT-Fat-3m-Lymphocytic-B_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A CIITA SCD APOBEC3H CREM	1.23e-05	187	71	5	63cc89ce24d3f8fb13479a501a20bfbd798d151a
ToppCell	droplet-Fat-Mat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H NXPE3	1.26e-05	188	71	5	d4113d0aaeefe6e07026cd02cd53ebc13a41a7ac
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A B4GALNT1 RASAL3 DMRTA1 RPL18	1.26e-05	188	71	5	5108238b7b8e9645c0cd75f8405a4638617e74a2
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 CIITA SCD APOBEC3H	1.26e-05	188	71	5	f72bc8965872da4d7d7990895beadbe36752314f
ToppCell	facs-MAT-Fat-18m-Lymphocytic-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 APOBEC3H CREM RPL18	1.26e-05	188	71	5	6cd04603bf5ca4d23a31ebced7535999583e1265
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H NXPE3	1.26e-05	188	71	5	2951c4dcece3c9e4fb627097a6c40fd12e261d0f
ToppCell	facs-GAT-Fat-18m-Lymphocytic-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 APOBEC3H CREM RPL18	1.26e-05	188	71	5	65dd6721b289167d7a716999a561462434a6481b
ToppCell	droplet-Fat-Mat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H NXPE3	1.26e-05	188	71	5	c9ed37e71eda66659bf4dd4dbbe4e852eefb8339
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A B4GALNT1 RASAL3 DMRTA1 RPL18	1.26e-05	188	71	5	ac267799fc1389b901d20b5d24c3179f00ca646f
ToppCell	facs-MAT-Fat-18m-Lymphocytic\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 APOBEC3H CREM RPL18	1.26e-05	188	71	5	613d4484d8d00ed18e5061bd0957b6beef6be8dd
ToppCell	facs-GAT-Fat-18m-Lymphocytic\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 APOBEC3H CREM RPL18	1.26e-05	188	71	5	ce8aaf2678d5777daedd131b62d9233038b0723f
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A RASAL3 SCD APOBEC3H RPL18	1.26e-05	188	71	5	3e0bc7c92b3946a03276dc8b6cffed5aa0681a8c
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A CIITA SCD APOBEC3H RPL18	1.36e-05	191	71	5	04ce9d7a5b5a221576648a6635fe9ec93cbb4ecd
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	NBAS CIITA TMEM30A PRKDC DOP1B	1.36e-05	191	71	5	9454f642c3621370fa23640b631301346b300950
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A CIITA SCD APOBEC3H RPL18	1.36e-05	191	71	5	9502533a7946626e1714a22a0f16c70d296edf16
ToppCell	droplet-Fat-Mat-18m-Lymphocytic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 CREM RPL18	1.39e-05	192	71	5	3f705f5aefb5d19e2b4cb551a2a68b96c1b8df26
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-B_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A CIITA SCD APOBEC3H RPL18	1.39e-05	192	71	5	b0686c0676f7658b560967840adb6c182792b075
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A RASAL3 SCD APOBEC3H RPL18	1.39e-05	192	71	5	432d07afedd872e81445a61bb64a382d110b723f
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A RASAL3 CREM RPL18 NXPE3	1.39e-05	192	71	5	0d96b24e5cadef45f0a7e380cd0415e80eca2e82
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A RASAL3 CREM RPL18 NXPE3	1.39e-05	192	71	5	757cc9d9e1a7b1e133c27aa9edccadfedf2a55d3
ToppCell	droplet-Fat-Mat-18m-Lymphocytic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 CREM RPL18	1.39e-05	192	71	5	45b9a9c1ef921b46023ea82027754cfdfa18cff1
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-B_cell-B_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A CIITA SCD APOBEC3H RPL18	1.39e-05	192	71	5	7e626ec5a4615e7e04a324937d5f0147dd17ca8e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A CIITA SCD APOBEC3H RPL18	1.43e-05	193	71	5	a808eb426b4ce9ddf7d6556b083abd9232a218b1
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-B_cell-B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A CIITA SCD APOBEC3H RPL18	1.43e-05	193	71	5	e1d0b2d2d6b65d32922e22d092848ac4200669d5
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A B4GALNT1 RASAL3 APOBEC3H RPL18	1.46e-05	194	71	5	95b088c8792bb5b99642cd3cca8c107f737d2ef2
ToppCell	normal_Lung-T/NK_cells-CD4+_Th\|normal_Lung / Location, Cell class and cell subclass	RPL23A RASAL3 APOBEC3H CREM RPL18	1.50e-05	195	71	5	d6c69f149f3d96fe83f920e38277dede102d04b5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RPL23A SCD WNT7B DMRTA1 RPL18	1.65e-05	199	71	5	afed9fefd1355eb3bc17fbc7ce04daad890a0f9f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	RPL23A SCD WNT7B DMRTA1 RPL18	1.65e-05	199	71	5	3c9bd4d4b166788f807eaaf4f74735949031c295
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CSPG4 DMRTA1 CHD7 ITPR2	6.08e-05	133	71	4	63d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCell	Bac-SEP-Lymphocyte-T_NK-CD4_CTL\|Bac-SEP / Disease, Lineage and Cell Type	RPL23A RASAL3 APOBEC3H PM20D1	1.18e-04	158	71	4	4beed58bf58253253fc7e5009294b35e3bb8eae3
ToppCell	356C-Epithelial_cells-Epithelial-C_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GCAT WNT7B CFTR DMRTA1	1.27e-04	161	71	4	78cb72c462167021195917a06052bcdc367ad890
ToppCell	356C-Epithelial_cells-Epithelial-C_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	GCAT WNT7B CFTR DMRTA1	1.27e-04	161	71	4	06e7becfd11d6ef1a45a9cfdfcb40b812600038e
ToppCell	facs-Heart-LA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A1 CFTR TGM7 HAO2	1.53e-04	169	71	4	421fb287c7e439d1870b7950c5e3ca34106e014a
ToppCell	facs-Heart-LA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A1 CFTR TGM7 HAO2	1.53e-04	169	71	4	383639ec4f9d0c6255e0881edca15cdd1980a37c
ToppCell	facs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT9 LOXL2 CHRD PM20D1	1.53e-04	169	71	4	b798b91567d2f49082e2d8a337169f241c8d2080
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNF ALKBH1 GCAT WNT7B	1.64e-04	172	71	4	1171e754fd503a0c1152162fcc12a115088a08c7
ToppCell	droplet-Lung-nan-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA SCD APOBEC3H NXPE3	1.68e-04	173	71	4	25d72fa7a84baf5660ead6da67327590f5c91860
ToppCell	droplet-Limb_Muscle-nan-3m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 RPL18	1.68e-04	173	71	4	a3399828c1829887ec30d5f37ba0a9978508924b
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A B4GALNT1 RASAL3 APOBEC3H	1.75e-04	175	71	4	f1d91cd49308cb501864cd16befaa43d6da828ca
ToppCell	droplet-Fat-Scat-21m-Lymphocytic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A RASAL3 CREM RPL18	1.75e-04	175	71	4	921168c3245cfd6e3fb6abc214b4b112045ac8d0
ToppCell	droplet-Fat-Scat-21m-Lymphocytic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A RASAL3 CREM RPL18	1.75e-04	175	71	4	fe10d18c5900871b43de793a3715118ae1a3a3c9
ToppCell	facs-GAT-Fat-3m-Lymphocytic\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 CHD7 CREM	1.79e-04	176	71	4	2e3f25a338842384517656d05776a52cbfc62b52
ToppCell	facs-GAT-Fat-3m-Lymphocytic-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 CHD7 CREM	1.79e-04	176	71	4	0823088bc6b19c7ad784d83c2ccdfae80611afab
ToppCell	facs-MAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A RASAL3 CHD7 NXPE3	1.83e-04	177	71	4	b5c20c1247f11ebc97e9cb47482564cd74e36ca6
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B4GALNT1 RASAL3 DMRTA1 DOP1B	1.83e-04	177	71	4	d6b7d387e7485ff52ce27f51df8b8050f49fd941
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 DMRTA1	1.87e-04	178	71	4	4112ac058e18dedb60e248ca43352fd43f54e77a
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 DMRTA1	1.87e-04	178	71	4	b2bd45f2fee0b4f7cb9fb7c74109f948d0581785
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-mature_NK_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 APOBEC3H DOP1B	1.87e-04	178	71	4	291ffc52b824e4f59078147eb640ef34e24fb450
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H	1.87e-04	178	71	4	ff80288fb54cdd25ce3e1c638b67d5db2a456e48
ToppCell	facs-Kidney-nan-18m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 CIITA POT1 CREM	1.91e-04	179	71	4	f4fd214a9865c635d8a744ce5e0eff45174d3de4
ToppCell	facs-Kidney-nan-18m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 CIITA POT1 CREM	1.91e-04	179	71	4	57d8d44a793314eec8f77030f4177bfe21d41652
ToppCell	facs-MAT-Fat-24m-Lymphocytic-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 APOBEC3H CREM RPL18	1.95e-04	180	71	4	f3f7a610db750fcb84d746a5ea0d8b57f9b7d901
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA SCD LMBRD1 RPL18	1.95e-04	180	71	4	243622eee35d38748e945677ff115616e763e3b4
ToppCell	facs-MAT-Fat-24m-Lymphocytic-B_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA SCD APOBEC3H CREM	1.95e-04	180	71	4	711719219bcbafdd505790eda895e7a33f21bed2
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A B4GALNT1 RASAL3 RPL18	1.95e-04	180	71	4	89d3befbea2b4c06d118d6b339545ddcc1bcfacb
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA SCD LMBRD1 RPL18	1.95e-04	180	71	4	3a8d9a71efe113d1df3933902a625c0a56812074
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Lymphocytic-B_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 SCD APOBEC3H CREM	1.95e-04	180	71	4	14ca8875af7cceead88fec147a4c0ef4d5a41f26
ToppCell	facs-MAT-Fat-24m-Lymphocytic\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 APOBEC3H CREM RPL18	1.95e-04	180	71	4	bb2f1b254371924b2045e9e1a81b6dbf4f00dd6a
ToppCell	metastatic_Brain-T/NK_cells-CD8_low_T\|metastatic_Brain / Location, Cell class and cell subclass	RPL23A RASAL3 APOBEC3H CREM	1.95e-04	180	71	4	57eced5e314681857a853f7e6bb8b429f157e80e
ToppCell	droplet-Lung-nan-21m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 DMRTA1	2.04e-04	182	71	4	0fbc70527059cab8be16ae7348c791dfff159604
ToppCell	droplet-Lung-nan-21m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 DMRTA1	2.04e-04	182	71	4	4d27bd13d5507862e8cca5def655f93b5c919a0e
ToppCell	droplet-Limb_Muscle-nan-24m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 SCD APOBEC3H CREM	2.04e-04	182	71	4	6946ab8d91fb8dce5af065f57a13659b8d97ed5c
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A RASAL3 DMRTA1 RPL18	2.04e-04	182	71	4	6339fc979aa097627924849f436bb9e9c14f4ce3
ToppCell	facs-Thymus-Flowthrough-24m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP6V0A1 CIITA SCD APOBEC3H	2.08e-04	183	71	4	0513bb73552bfee609877d924fa97684200f595c
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Lymphocytic-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 SCD APOBEC3H CREM	2.08e-04	183	71	4	56038766980a4186ecd3b4a327a91c12979d2364
ToppCell	facs-Thymus-Flowthrough-24m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP6V0A1 CIITA SCD APOBEC3H	2.08e-04	183	71	4	6eeef55071ae25a61616df4fcfb2cea560aa7923
ToppCell	droplet-Lung-nan-18m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A RASAL3 SCD APOBEC3H	2.08e-04	183	71	4	23630b2e2c14a2a42e207cbb650459d7838fa9f1
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL23A RASAL3 APOBEC3H RPL18	2.08e-04	183	71	4	80534ff71581f5d82ab6f6ae5a491f55e8411f28
ToppCell	droplet-Lung-nan-21m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL23A B4GALNT1 RASAL3 APOBEC3H	2.08e-04	183	71	4	d03a35fd69a1307b99928b73fd5879aed2fda2b5
ToppCell	normal_Lung-T/NK_cells-Exhausted_CD8+_T\|normal_Lung / Location, Cell class and cell subclass	RPL23A RASAL3 APOBEC3H CREM	2.08e-04	183	71	4	a2901707d0f0900ff91c08c9152dad0b6c191cca
ToppCell	facs-Thymus-Flowthrough-24m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP6V0A1 CIITA SCD APOBEC3H	2.08e-04	183	71	4	85b2335fa938a94e74251bd8d99de1bd21265ac9
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Lymphocytic\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 SCD APOBEC3H CREM	2.08e-04	183	71	4	eb2f37c3d6d0502fb9eb512537fc2a002a1b92ed
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALNT1 RASAL3 CIITA SCD	2.08e-04	183	71	4	20f7b6ec2462032eda957a893ca76d5a5a01333d
Disease	lung cancer (is_implicated_in)	IRS4 CFTR POT1	5.65e-04	74	64	3	DOID:1324 (is_implicated_in)
Disease	refractive error	WNT7B C16orf86 CHD7 CREB1 ITPR2	7.14e-04	326	64	5	MONDO_0004892
Disease	Liver carcinoma	CCNF SCAP SCD SLC22A1 CSPG4 HAO2	8.06e-04	507	64	6	C2239176
Disease	Immunologic Deficiency Syndromes	NBAS CHD7	1.14e-03	23	64	2	C0021051

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRPSLYRRILRRLAS	AGK	271	Q53H12
LRLERKAQRLRPLYQ	C16orf86	181	Q6ZW13
RPILRKGYRQRLELS	CFTR	21	P13569
RPIYRFTQEDLRKRR	CSPG4	1076	Q6UVK1
RLRALITSIRRFYPT	B4GALNT1	291	Q00973
LRYKEATKRRPRSLL	ALKBH1	151	Q13686
RYLKRLQPGTLRARQ	CIITA	791	P33076
YRRLALLRRLTVLPF	ATP13A1	56	Q9HD20
KRRLRRPYYPRKALL	APOBEC3H	16	Q6NTF7
ASRTLYRIELLRKIR	CHD7	2051	Q9P2D1
ARRLRVLPSERYKEL	RASAL3	421	Q86YV0
RYITKRPVRDRLLRE	PDZRN3	931	Q9UPQ7
LLRRNREPRFLDYLS	ITPR2	621	Q14571
LLLIRKYIPRRSFFI	PM20D1	171	Q6GTS8
ATRRRLAVLPYELRF	NOB1	41	Q9ULX3
RLYKIRRGRTRPQAL	LMBRD1	396	Q9NUN5
NLRYSLLPRRLLISK	DOP1B	51	Q9Y3R5
IRIRAILSTYRKRTP	LOXL2	186	Q9Y4K0
TYISAIRERFPKLLR	NXF1	336	Q9UBU9
SRTFYLQLRAPLKTR	GARIN5A	206	Q6IPT2
LVSLLRQRARPYLFS	GCAT	281	O75600
KRFSVRYLRPARSLV	TWNK	191	Q96RR1
RKRPRTITKNYRLVS	NBAS	506	A2RRP1
KVRYKRALLLLRRRS	FKBP6	191	O75344
YLRRRLVPRYRLQLL	CCNF	341	P41002
RALRFLEKAQRLYPT	DNAJB12	26	Q9NXW2
DILTKIFPNYRRSRL	DMRTA1	331	Q5VZB9
KLYLRRQRLLRDLRP	CYP4X1	31	Q8N118
RNIKARLLLYVRASP	IDI2-AS1	86	Q9NZ38
SRDNPRRLRVLLRYK	PRMT6	346	Q96LA8
LPTFRKLYRLIERKS	TMEM30A	266	Q9NV96
REILSRRPSYRKILN	CREB1	111	P16220
KFTAILYRTLERRRL	MAP7D3	141	Q8IWC1
YLRRFKCLRTLSLSR	DRC3	151	Q9H069
GILRLRRKFERILYV	HDAC8	161	Q9BY41
RREILSRRPSYRKIL	CREM	111	Q03060
RNLRLPKRLRVVYFL	SCAP	496	Q12770
PKRLRVVYFLARTRL	SCAP	501	Q12770
DLFRTPRLRKRTFIL	SLC22A1	336	O15245
YLLLSRLILESKRRR	IRS4	191	O14654
LRATYQLTKARPRVL	VARS2	916	Q5ST30
SLPRRRRPAYRTFIK	UTP15	326	Q8TED0
RKLLSRYRLPVATRE	TCAF1	466	Q9Y4C2
FPLEVYIRRLRNIRR	NXPE3	451	Q969Y0
LRRLFRERYRLHPKF	TACSTD2	176	P09758
AFKRIRLRPRYLRDV	HAO2	41	Q9NYQ3
AYVLRRRRKKLPFRS	SLITRK3	676	O94933
RIRAKLRSYKPRRLF	POT1	361	Q9NUX5
LRSYKPRRLFQSVKL	POT1	366	Q9NUX5
FRRPKTLRLRRQPKY	RPL23A	46	P62750
IPLLRKRRFQLYRST	SPDYE2B	306	A6NHP3
RRLPRPDSLIFYRQK	FAM110D	76	Q8TAY7
RYLRAKDQRRFPLLI	B3GNT9	86	Q6UX72
RRYQPRLRFQKQRLL	CHPF2	416	Q9P2E5
LRFSISYRRLDRPTR	CHRD	196	Q9H2X0
RKLTLAQLYRIRTTL	PLEKHG5	981	O94827
SAIRRRFEKRIYIPL	VPS4B	286	O75351
LRQPTFLRIKQLRSY	WNT7B	246	P56706
RLLVKLYRFLARRTN	RPL18	26	Q07020
NPRARKYRSRIPLVR	SPDYE21	321	A0A494C086
KYRSRIPLVRKRRFQ	SPDYE21	326	A0A494C086
IPLLRKRRFQLYRST	SPDYE2	306	Q495Y8
IPLLRKRRFQLYRST	SPDYE6	306	P0CI01
PLLRKRRFQLYRSMN	SPDYE1	241	Q8NFV5
RSYKARLPLRLFLII	SCD	126	O00767
ARLKFPRLLQIIERY	PRKDC	3461	P78527
LLFKPLVLRRQYLRR	ATP6V0A1	651	Q93050
RLYNSLKSRSVRPRL	UBP1	416	Q9NZI7
VRLRYFLKVTIVRRL	VPS26A	126	O75436
LKIRPYFNRVIRPRR	VRTN	196	Q9H8Y1
KRLTVRRGQPFYLRL	TGM7	31	Q96PF1
TESYLRPLFRKLRKR	PRPF18	226	Q99633
RRYRRPRTRFLSKQL	LEUTX	6	A8MZ59
PYDFRRLLRKTSQRR	MYO3A	1596	Q8NEV4