| GeneOntologyMolecularFunction | G protein-coupled receptor activity | OR5W2 TAPT1 LPAR5 OR4C6 OR8K5 ADGRB1 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 ADORA3 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 OR4A4P PTGDR2 OR4C5 ADGRA3 OR2A2 | 2.70e-12 | 884 | 104 | 25 | GO:0004930 |
| GeneOntologyMolecularFunction | olfactory receptor activity | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 8.80e-12 | 431 | 104 | 18 | GO:0004984 |
| GeneOntologyMolecularFunction | transmembrane signaling receptor activity | OR5W2 TAPT1 LPAR5 OR4C6 OR8K5 ADGRB1 OR2J3 PTCH1 OR10T2 OR6P1 OR9A1P OR1N2 ADORA3 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 OR4A4P PTGDR2 OR4C5 ADGRA3 OR2A2 | 4.19e-09 | 1353 | 104 | 26 | GO:0004888 |
| GeneOntologyMolecularFunction | odorant binding | OR5W2 OR8K5 OR10T2 OR5AC2 OR13A1 OR2A25 | 5.36e-05 | 127 | 104 | 6 | GO:0005549 |
| GeneOntologyBiologicalProcess | sensory perception of smell | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 GNAL OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 1.82e-12 | 465 | 104 | 19 | GO:0007608 |
| GeneOntologyBiologicalProcess | sensory perception of chemical stimulus | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 GNAL OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 3.39e-12 | 547 | 104 | 20 | GO:0007606 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 3.80e-12 | 485 | 104 | 19 | GO:0050907 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of smell | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 5.39e-12 | 432 | 104 | 18 | GO:0050911 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 1.45e-11 | 524 | 104 | 19 | GO:0009593 |
| GeneOntologyBiologicalProcess | G protein-coupled receptor signaling pathway | OR5W2 TAPT1 LPAR5 OR4C6 OR8K5 ADGRB1 OR2J3 APLP1 OR10T2 OR6P1 ITPR1 OR9A1P OR1N2 ADORA3 OR4C3 TAS2R13 OR5AC2 GRK3 OR13A1 OR2A25 OR4B1 GNAL OR51V1 OR52A1 OR4A4P PTGDR2 OR4C5 ADGRA3 OR2A2 | 2.97e-11 | 1395 | 104 | 29 | GO:0007186 |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 8.76e-11 | 582 | 104 | 19 | GO:0050906 |
| GeneOntologyBiologicalProcess | detection of stimulus | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 ANO3 OR52A1 OR4A4P OR4C5 OR2A2 | 4.74e-10 | 722 | 104 | 20 | GO:0051606 |
| GeneOntologyBiologicalProcess | sensory perception | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR9A1P OR1N2 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 GNAL OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 3.44e-07 | 1072 | 104 | 20 | GO:0007600 |
| GeneOntologyCellularComponent | dendrite terminus | PTCH1 CYFIP1 GRK3 | 1.28e-04 | 20 | 104 | 3 | GO:0044292 |
| Domain | Olfact_rcpt | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR1N2 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 OR4C5 OR2A2 | 3.42e-10 | 393 | 101 | 16 | IPR000725 |
| Domain | 7tm_1 | OR5W2 LPAR5 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR1N2 ADORA3 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 PTGDR2 OR4C5 OR2A2 | 3.31e-09 | 677 | 101 | 19 | PF00001 |
| Domain | G_PROTEIN_RECEP_F1_1 | OR5W2 LPAR5 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR1N2 ADORA3 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 PTGDR2 OR4C5 OR2A2 | 4.02e-09 | 685 | 101 | 19 | PS00237 |
| Domain | G_PROTEIN_RECEP_F1_2 | OR5W2 LPAR5 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR1N2 ADORA3 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 PTGDR2 OR4C5 OR2A2 | 4.63e-09 | 691 | 101 | 19 | PS50262 |
| Domain | GPCR_Rhodpsn | OR5W2 LPAR5 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR1N2 ADORA3 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 PTGDR2 OR4C5 OR2A2 | 4.74e-09 | 692 | 101 | 19 | IPR000276 |
| Domain | GPCR_Rhodpsn_7TM | OR5W2 LPAR5 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR1N2 ADORA3 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 OR51V1 OR52A1 PTGDR2 OR2A2 | 1.78e-08 | 670 | 101 | 18 | IPR017452 |
| Domain | ARM-type_fold | USP34 DOCK11 XPO4 HEATR1 USP9Y MEI1 ITPR1 FMNL3 MROH7 NUP188 | 1.51e-05 | 339 | 101 | 10 | IPR016024 |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR1N2 OR4C3 OR5AC2 OR13A1 OR2A25 OR4B1 GNAL OR51V1 OR52A1 OR4C5 OR2A2 | 1.66e-10 | 417 | 81 | 17 | M4072 |
| Pathway | REACTOME_SENSORY_PERCEPTION | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 CASK OR1N2 OR4C3 TAS2R13 OR5AC2 OR13A1 OR2A25 OR4B1 GNAL OR51V1 OR52A1 OR4C5 OR2A2 | 2.27e-09 | 636 | 81 | 19 | M41834 |
| Pathway | KEGG_OLFACTORY_TRANSDUCTION | OR4C6 OR8K5 OR2J3 OR10T2 OR1N2 OR4C3 OR5AC2 GRK3 OR13A1 OR2A25 OR4B1 GNAL OR51V1 OR52A1 OR2A2 | 4.85e-09 | 389 | 81 | 15 | M14091 |
| Pubmed | Different evolutionary processes shaped the mouse and human olfactory receptor gene families. | OR5W2 OR4C6 OR8K5 OR2J3 OR6P1 OR9A1P OR1N2 OR4C3 OR13A1 OR2A25 OR4B1 OR51V1 OR4A4P OR4C5 OR2A2 | 1.52e-13 | 340 | 106 | 15 | 11875048 |
| Pubmed | The olfactory receptor gene superfamily of the mouse. | OR5W2 OR4C6 OR8K5 OR2J3 OR6P1 OR9A1P OR1N2 OR4C3 OR13A1 OR2A25 OR4B1 OR51V1 OR4A4P OR4C5 OR2A2 | 1.52e-13 | 340 | 106 | 15 | 11802173 |
| Pubmed | A unified nomenclature for vertebrate olfactory receptors. | OR5W2 OR4C6 OR8K5 OR2J3 OR6P1 OR9A1P OR1N2 OR4C3 OR13A1 OR2A25 OR4B1 OR51V1 OR4A4P OR4C5 OR2A2 | 1.73e-13 | 343 | 106 | 15 | 32295537 |
| Pubmed | Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. | OR5W2 OR4C6 OR8K5 OR2J3 OR6P1 OR9A1P OR1N2 OR4C3 OR13A1 OR2A25 OR4B1 OR51V1 OR4A4P OR4C5 OR2A2 | 1.96e-13 | 346 | 106 | 15 | 14611657 |
| Pubmed | The human olfactory receptor gene family. | OR5W2 OR4C6 OR8K5 OR2J3 OR10T2 OR6P1 OR1N2 OR4C3 OR13A1 OR4B1 OR51V1 OR52A1 OR4A4P OR4C5 OR2A2 | 1.10e-10 | 541 | 106 | 15 | 14983052 |
| Pubmed | E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. | ANK1 LPAR5 DOCK11 ADGRB1 NELFB GTF3C1 TBK1 POP1 PHF14 OR4B1 NUP188 RPA1 | 2.64e-06 | 736 | 106 | 12 | 29676528 |
| Pubmed | DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho-/- mice. | DPP4 KL | 9.20e-06 | 2 | 106 | 2 | 29195509 |
| Pubmed | The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1. | CYP4Z1 CYP4Z2P | 9.20e-06 | 2 | 106 | 2 | 25701119 |
| Pubmed | The competing endogenous RNA network of CYP4Z1 and pseudogene CYP4Z2P exerts an anti-apoptotic function in breast cancer. | CYP4Z1 CYP4Z2P | 9.20e-06 | 2 | 106 | 2 | 28236635 |
| Pubmed | Rare sequence variants in ANO3 and GNAL in a primary torsion dystonia series and controls. | GNAL ANO3 | 9.20e-06 | 2 | 106 | 2 | 24151159 |
| Pubmed | Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. | CYP4Z1 CYP4Z2P | 9.20e-06 | 2 | 106 | 2 | 15059886 |
| Pubmed | Mutations in ANO3 and GNAL gene in thirty-three isolated dystonia families. | GNAL ANO3 | 9.20e-06 | 2 | 106 | 2 | 25847575 |
| Pubmed | Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. | PPFIA4 NELFB ARHGAP39 POP1 TTC21B PHF14 CEP152 TASOR TMCC1 | 2.09e-05 | 493 | 106 | 9 | 15368895 |
| Pubmed | FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia. | ANK1 DOCK11 ETF1 USP9Y MEI1 CYFIP1 GTF3C1 ERCC6L2 ANO3 | 2.23e-05 | 497 | 106 | 9 | 36774506 |
| Pubmed | Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages. | NELFB NR3C1 | 2.76e-05 | 3 | 106 | 2 | 29424686 |
| Pubmed | Klotho inhibits PKCα/p66SHC-mediated podocyte injury in diabetic nephropathy. | SHC1 KL | 2.76e-05 | 3 | 106 | 2 | 31207271 |
| Pubmed | Microdeletion of 9q22.3: A patient with minimal deletion size associated with a severe phenotype. | PTCH1 ERCC6L2 | 2.76e-05 | 3 | 106 | 2 | 33960642 |
| Pubmed | T cell development critically depends on prethymic stromal patched expression. | NR3C1 PTCH1 | 2.76e-05 | 3 | 106 | 2 | 21317383 |
| Pubmed | A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties. | NELFB NR3C1 | 2.76e-05 | 3 | 106 | 2 | 24097989 |
| Pubmed | Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells. | CYP4Z1 CYP4Z2P | 2.76e-05 | 3 | 106 | 2 | 30832689 |
| Pubmed | Hundreds of variants clustered in genomic loci and biological pathways affect human height. | PAPPA2 MYO9B SLC38A9 OR2J3 PTCH1 TASOR | 3.36e-05 | 198 | 106 | 6 | 20881960 |
| Pubmed | The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei. | CNOT10 HEATR1 DHX33 INO80 ARHGAP39 NKRF SLC30A6 CASK GREB1L CYFIP1 CTR9 POP1 PHF14 TASOR TMCC1 | 4.91e-05 | 1497 | 106 | 15 | 31527615 |
| Pubmed | BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation. | ADGRB1 PTCH1 | 5.50e-05 | 4 | 106 | 2 | 29894688 |
| Pubmed | Association of the type 1 inositol (1,4,5)-trisphosphate receptor with 4.1N protein in neurons. | ITPR1 CASK | 5.50e-05 | 4 | 106 | 2 | 12676536 |
| Pubmed | DEFOG: a practical scheme for deciphering families of genes. | OR5W2 OR2J3 OR1N2 OR4B1 OR4A4P OR2A2 | 5.88e-05 | 219 | 106 | 6 | 12213199 |
| Pubmed | Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. | HEATR1 DHX33 NKRF POP1 PHF14 NUP188 TASOR | 7.36e-05 | 332 | 106 | 7 | 25693804 |
| Pubmed | Vax1 Plays an Indirect Role in the Etiology of Murine Cleft Palate. | VAX1 PTCH1 | 9.15e-05 | 5 | 106 | 2 | 28771384 |
| Pubmed | Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle. | NELFB NR3C1 | 9.15e-05 | 5 | 106 | 2 | 23950223 |
| Pubmed | Conditional regulation of the human CYP4X1 and CYP4Z1 genes. | CYP4Z1 NR3C1 | 9.15e-05 | 5 | 106 | 2 | 15797250 |
| Pubmed | Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity. | USP34 SPNS1 ADCK1 SHC1 SLC30A6 CYFIP1 GTF3C1 CTR9 SLC35B4 TBK1 NUP188 | 1.07e-04 | 910 | 106 | 11 | 36736316 |
| Pubmed | Transcriptome analysis of mouse stem cells and early embryos. | PAPPA2 USP34 DOCK11 WDR81 NR3C1 ITPR1 POP1 | 1.28e-04 | 363 | 106 | 7 | 14691545 |
| Pubmed | Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein. | DENND4A NR3C1 NKRF ITPR1 GTF3C1 CTR9 TBK1 POP1 TASOR | 1.73e-04 | 650 | 106 | 9 | 38777146 |
| Pubmed | SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response. | TBK1 SNX8 | 1.91e-04 | 7 | 106 | 2 | 33110251 |
| Pubmed | A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling. | USP34 SPNS1 SHC1 XPO4 HEATR1 CASK CYFIP1 GTF3C1 CTR9 SNX8 NUP188 | 1.94e-04 | 974 | 106 | 11 | 28675297 |
| Pubmed | Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. | XPO4 ARHGAP39 GREB1L CFAP74 | 2.75e-04 | 102 | 106 | 4 | 11214970 |
| Pubmed | Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. | USP34 SPNS1 GREB1L GTF3C1 TBK1 PCCA TASOR | 3.02e-04 | 418 | 106 | 7 | 34709266 |
| Pubmed | Hedgehog signaling regulates ciliary localization of mouse odorant receptors. | PTCH1 GNAL | 3.27e-04 | 9 | 106 | 2 | 29078327 |
| Pubmed | Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging. | USP34 USP9Y | 3.27e-04 | 9 | 106 | 2 | 37149635 |
| Pubmed | FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. | SHC1 KL | 4.08e-04 | 10 | 106 | 2 | 10629055 |
| Pubmed | Depletion of Ric-8B leads to reduced mTORC2 activity. | PTCH1 GNAL | 4.08e-04 | 10 | 106 | 2 | 32392211 |
| Pubmed | Reciprocal interaction between SIRT6 and APC/C regulates genomic stability. | DOCK11 NKRF ITPR1 GTF3C1 CTR9 POP1 NUP188 | 4.11e-04 | 440 | 106 | 7 | 34244565 |
| Pubmed | Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2Prame complex. | FBXW9 FBH1 KLHL42 | 4.31e-04 | 48 | 106 | 3 | 33504946 |
| Pubmed | Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. | USP34 HEATR1 INO80 PTCH1 ITPR1 RHOH CTR9 POP1 NUP188 RPA1 TASOR | 4.80e-04 | 1084 | 106 | 11 | 11544199 |
| Pubmed | Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy. | LPAR5 ETF1 HEATR1 DHX33 TBK1 POP1 NSMAF | 4.95e-04 | 454 | 106 | 7 | 33226137 |
| Pubmed | Complementary Gli activity mediates early patterning of the mouse visual system. | VAX1 PTCH1 | 4.97e-04 | 11 | 106 | 2 | 16342201 |
| Pubmed | Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. | LPAR5 CNOT10 HEATR1 DHX33 CTR9 TBK1 RPA1 | 5.15e-04 | 457 | 106 | 7 | 32968282 |
| Pubmed | H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. | HEATR1 DHX33 INO80 NKRF GTF3C1 CTR9 POP1 PHF14 NUP188 RPA1 PCCA TASOR | 5.88e-04 | 1294 | 106 | 12 | 30804502 |
| Pubmed | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. | SLC38A9 KAT6A ARHGAP39 SEC22A CASK GRK3 GTF3C1 TBK1 TTC21B PHF14 PCCA TMCC1 NSMAF | 6.06e-04 | 1489 | 106 | 13 | 28611215 |
| Pubmed | The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation. | ETF1 NELFB HEATR1 NKRF CYFIP1 CTR9 NUP188 RPA1 | 7.66e-04 | 638 | 106 | 8 | 33239621 |
| Pubmed | FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. | FBH1 RPA1 | 8.18e-04 | 14 | 106 | 2 | 23319600 |
| Pubmed | Chordin and noggin promote organizing centers of forebrain development in the mouse. | VAX1 PTCH1 | 8.18e-04 | 14 | 106 | 2 | 12397106 |
| Pubmed | MYC multimers shield stalled replication forks from RNA polymerase. | ETF1 HEATR1 DHX33 NKRF GTF3C1 CTR9 POP1 PHF14 RPA1 PCCA | 8.98e-04 | 989 | 106 | 10 | 36424410 |
| Pubmed | Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. | OR51V1 OR52A1 | 9.41e-04 | 15 | 106 | 2 | 11121057 |
| Pubmed | THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia. | PTCH1 TTC21B | 9.41e-04 | 15 | 106 | 2 | 18327258 |
| Pubmed | Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis. | VAX1 PTCH1 | 9.41e-04 | 15 | 106 | 2 | 24590292 |
| Pubmed | Defining the human deubiquitinating enzyme interaction landscape. | FBXW9 CNOT10 ETF1 ADGRB1 DHX33 CASK TBK1 KLHL42 GNAL NUP188 | 1.01e-03 | 1005 | 106 | 10 | 19615732 |
| Pubmed | Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. | MEI1 RPA1 | 1.07e-03 | 16 | 106 | 2 | 17696610 |
| Pubmed | A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18. | NR3C1 GNAL | 1.21e-03 | 17 | 106 | 2 | 1354644 |
| Pubmed | The Lim homeobox gene Lhx2 is required for olfactory sensory neuron identity. | OR4B1 GNAL | 1.21e-03 | 17 | 106 | 2 | 15456728 |
| Pubmed | Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians. | ANK1 MYO9B | 1.21e-03 | 17 | 106 | 2 | 24647736 |
| Pubmed | RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways. | PTCH1 ITPR1 | 1.36e-03 | 18 | 106 | 2 | 14687547 |
| Pubmed | The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex. | NPAS3 CYFIP1 PCCA | 1.41e-03 | 72 | 106 | 3 | 33726789 |
| Pubmed | Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex. | DOCK11 NELFB CYFIP1 GTF3C1 POP1 RPA1 | 1.43e-03 | 399 | 106 | 6 | 37536630 |
| Pubmed | SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development. | NR3C1 PTCH1 | 1.52e-03 | 19 | 106 | 2 | 18206867 |
| Pubmed | Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. | PAPPA2 CACNA2D3 | 1.52e-03 | 19 | 106 | 2 | 24315451 |
| Pubmed | Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain. | PTCH1 TTC21B | 1.52e-03 | 19 | 106 | 2 | 19732765 |
| Pubmed | Odorant and vomeronasal receptor genes in two mouse genome assemblies. | OR5W2 OR8K5 OR4B1 | 1.52e-03 | 74 | 106 | 3 | 15081110 |
| Pubmed | mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking. | PPFIA4 CASK | 1.69e-03 | 20 | 106 | 2 | 23791195 |
| Pubmed | The ULK1-FBXW5-SEC23B nexus controls autophagy. | FBXW9 FBH1 | 1.69e-03 | 20 | 106 | 2 | 30596474 |
| Pubmed | The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. | CNOT10 ETF1 CYFIP1 CTR9 POP1 | 1.73e-03 | 281 | 106 | 5 | 24163370 |
| Pubmed | LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. | SHC1 GTF3C1 RPA1 | 1.84e-03 | 79 | 106 | 3 | 26446488 |
| Pubmed | The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression. | NKRF POP1 | 1.86e-03 | 21 | 106 | 2 | 35232816 |
| Pubmed | Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway. | PTCH1 TTC21B | 2.04e-03 | 22 | 106 | 2 | 19223390 |
| Pubmed | Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. | PTCH1 SNX8 | 2.04e-03 | 22 | 106 | 2 | 17983586 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | USP34 FAM89A LPAR5 MYO9B KAT6A SHC1 INO80 PTCH1 SNX8 NUP188 | 2.04e-03 | 1105 | 106 | 10 | 35748872 |
| Pubmed | The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis. | MYO9B KAT6A HEATR1 DHX33 NKRF GTF3C1 POP1 TASOR | 2.29e-03 | 759 | 106 | 8 | 35915203 |
| Pubmed | Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. | DENND4A DOCK11 CNOT10 NELFB TBK1 CEP152 | 2.50e-03 | 446 | 106 | 6 | 24255178 |
| Pubmed | Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. | INO80 ANO3 | 2.64e-03 | 25 | 106 | 2 | 32737294 |
| Pubmed | Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. | DPP4 SPNS1 ARHGAP39 | 3.02e-03 | 94 | 106 | 3 | 25201988 |
| GeneFamily | Olfactory receptors, family 4 | OR4C6 OR4C3 OR4B1 OR4A4P OR4C5 | 2.53e-04 | 129 | 79 | 5 | 151 |
| GeneFamily | WD repeat domain containing|BEACH domain containing | WDR81 NSMAF | 6.65e-04 | 9 | 79 | 2 | 1230 |
| GeneFamily | WD repeat domain containing|GRAM domain containing|BEACH domain containing | TBC1D8B NSMAF | 1.43e-03 | 13 | 79 | 2 | 1146 |
| GeneFamily | DNA helicases | INO80 FBH1 | 2.46e-03 | 17 | 79 | 2 | 1167 |
| Disease | sphingolipidosis (implicated_via_orthology) | SPNS1 SPNS3 | 3.40e-05 | 3 | 100 | 2 | DOID:1927 (implicated_via_orthology) |
| Disease | 10-undecenoate 11:1n1 measurement | CYP4Z1 CYP4Z2P | 2.36e-04 | 7 | 100 | 2 | EFO_0021099 |
| Disease | nitric oxide exhalation measurement | PAPPA2 ANO3 CACNA2D3 | 2.92e-04 | 38 | 100 | 3 | EFO_0005536 |
| Disease | neuronal ceroid lipofuscinosis (implicated_via_orthology) | SPNS1 SPNS3 | 1.01e-03 | 14 | 100 | 2 | DOID:14503 (implicated_via_orthology) |
| Disease | Dystonia, Limb | GNAL ANO3 | 1.50e-03 | 17 | 100 | 2 | C0751093 |
| Disease | Dystonia, Diurnal | GNAL ANO3 | 1.50e-03 | 17 | 100 | 2 | C0393610 |
| Disease | Dystonia, Paroxysmal | GNAL ANO3 | 1.68e-03 | 18 | 100 | 2 | C0393588 |
| Disease | gestational age, birth measurement | NPAS3 CACNA2D3 | 2.29e-03 | 21 | 100 | 2 | EFO_0005112, EFO_0006921 |
| Disease | alcohol drinking | HEATR1 INO80 NEK11 | 2.66e-03 | 81 | 100 | 3 | EFO_0004329 |
