Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation activator activity

DAZ1 DAZ2 DAZ4

3.59e-0615413GO:0008494
GeneOntologyMolecularFunction5-methylcytosine dioxygenase activity

TET2 TET3

1.23e-053412GO:0070579
GeneOntologyMolecularFunctionmRNA 3'-UTR binding

DAZ1 FUS ILF3 DAZ2 DAZ4 RBMS1

1.98e-05276416GO:0003730
GeneOntologyMolecularFunctionnuclear receptor binding

TRERF1 NR4A3 FUS PROX1

5.75e-04187414GO:0016922
GeneOntologyMolecularFunctioncalcium-dependent protein binding

VPS37C DMBT1 ANXA7

1.07e-0398413GO:0048306
GeneOntologyMolecularFunctiontranslation regulator activity, nucleic acid binding

DAZ1 DAZ2 DAZ4

1.57e-03112413GO:0090079
GeneOntologyMolecularFunctionmetalloendopeptidase activity

MEP1B TLL1 TLL2

1.91e-03120413GO:0004222
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NR4A3 RFX6 TBR1 HOXC13 TET3 CIC SOX30 PROX1 HOXA1

2.40e-031459419GO:0000977
GeneOntologyMolecularFunctionmRNA binding

DAZ1 FUS ILF3 DAZ2 DAZ4 RBMS1

2.75e-03694416GO:0003729
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NR4A3 RFX6 TBR1 HOXC13 TET3 SOX30 PROX1 HOXA1

3.35e-031244418GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NR4A3 RFX6 TBR1 HOXC13 TET3 SOX30 PROX1 HOXA1

3.83e-031271418GO:0000987
GeneOntologyMolecularFunctiontranscription coactivator binding

TRERF1 NR4A3

5.50e-0354412GO:0001223
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

NR4A3 RFX6 HOXC13 SOX30 HOXA1

5.55e-03560415GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

NR4A3 RFX6 HOXC13 SOX30 HOXA1

5.80e-03566415GO:0001216
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

TRERF1 NR4A3 FUS HOXC13 PROX1

6.52e-03582415GO:0140297
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PCSK5 TLL1 TLL2

6.93e-03190413GO:0004252
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

NR4A3 RFX6 TBR1 HOXC13 CIC SOX30 PROX1 HOXA1

7.19e-031412418GO:0000981
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

TET2 TET3

7.88e-0365412GO:0016706
GeneOntologyMolecularFunctionmetallopeptidase activity

MEP1B TLL1 TLL2

7.98e-03200413GO:0008237
GeneOntologyMolecularFunctionserine-type peptidase activity

PCSK5 TLL1 TLL2

8.76e-03207413GO:0008236
GeneOntologyMolecularFunctionzinc ion binding

MEP1B TET2 NR4A3 TET3 TLL1 TLL2

9.18e-03891416GO:0008270
GeneOntologyMolecularFunctionserine hydrolase activity

PCSK5 TLL1 TLL2

9.35e-03212413GO:0017171
GeneOntologyBiologicalProcessfemale meiosis II

DAZ1 DAZ2 DAZ4

1.56e-076423GO:0007147
GeneOntologyBiologicalProcessmeiosis II

DAZ1 DAZ2 DAZ4

1.56e-076423GO:0007135
GeneOntologyBiologicalProcessmeiosis II cell cycle process

DAZ1 DAZ2 DAZ4

1.56e-076423GO:0061983
GeneOntologyBiologicalProcesssemicircular canal morphogenesis

NR4A3 EYA1 HOXA1

6.54e-079423GO:0048752
GeneOntologyBiologicalProcesssemicircular canal development

NR4A3 EYA1 HOXA1

1.28e-0611423GO:0060872
GeneOntologyBiologicalProcessear morphogenesis

NR4A3 EYA4 EYA1 PROX1 HOXA1

1.48e-05154425GO:0042471
GeneOntologyBiologicalProcessmRNA stabilization

DAZ1 FUS DAZ2 DAZ4

1.80e-0577424GO:0048255
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

DAZ1 DAZ2 DAZ4

1.98e-0526423GO:0045836
GeneOntologyBiologicalProcesspositive regulation of translational initiation

DAZ1 DAZ2 DAZ4

2.76e-0529423GO:0045948
GeneOntologyBiologicalProcessnegative regulation of mRNA catabolic process

DAZ1 FUS DAZ2 DAZ4

2.92e-0587424GO:1902373
GeneOntologyBiologicalProcessRNA stabilization

DAZ1 FUS DAZ2 DAZ4

3.06e-0588424GO:0043489
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA stabilization

DAZ1 DAZ2 DAZ4

3.39e-0531423GO:0070935
GeneOntologyBiologicalProcessnegative regulation of RNA catabolic process

DAZ1 FUS DAZ2 DAZ4

5.25e-05101424GO:1902369
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

DAZ1 DAZ2 DAZ4

5.81e-0537423GO:0051446
GeneOntologyBiologicalProcesssensory organ morphogenesis

NR4A3 EYA4 EYA1 HOXC13 PROX1 HOXA1

6.41e-05343426GO:0090596
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

TRERF1 TET2 NR4A3 RFX6 EYA1 TBR1 HOXC13 TET3 SOX30 PROX1 HOXA1

7.66e-0513904211GO:0045944
GeneOntologyBiologicalProcesspattern specification process

PCSK5 EYA1 TBR1 HOXC13 TLL1 TLL2 HOXA1

8.38e-05526427GO:0007389
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

DAZ1 FUS DAZ2 DAZ4

8.72e-05115424GO:1903312
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

DAZ1 DAZ2 DAZ4

1.05e-0445423GO:0040020
GeneOntologyBiologicalProcessoocyte maturation

DAZ1 DAZ2 DAZ4

1.20e-0447423GO:0001556
GeneOntologyBiologicalProcessinner ear morphogenesis

NR4A3 EYA1 PROX1 HOXA1

1.36e-04129424GO:0042472
GeneOntologyBiologicalProcessinner ear development

NR4A3 EYA4 EYA1 PROX1 HOXA1

1.57e-04253425GO:0048839
GeneOntologyBiologicalProcessfemale meiotic nuclear division

DAZ1 DAZ2 DAZ4

1.62e-0452423GO:0007143
GeneOntologyBiologicalProcessouter ear morphogenesis

EYA1 HOXA1

1.80e-0410422GO:0042473
GeneOntologyBiologicalProcessotic vesicle morphogenesis

EYA1 PROX1

2.64e-0412422GO:0071600
GeneOntologyBiologicalProcessear development

NR4A3 EYA4 EYA1 PROX1 HOXA1

2.72e-04285425GO:0043583
GeneOntologyBiologicalProcessviral process

CALCOCO2 PCSK5 VPS37C ILF3 CR2 PROX1

3.31e-04464426GO:0016032
GeneOntologyBiologicalProcesscolumnar/cuboidal epithelial cell differentiation

RFX6 EYA1 DMBT1 PROX1

3.41e-04164424GO:0002065
GeneOntologyBiologicalProcessregionalization

PCSK5 TBR1 HOXC13 TLL1 TLL2 HOXA1

3.88e-04478426GO:0003002
GeneOntologyBiologicalProcessprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

VPS37C HGS

4.18e-0415422GO:0043328
GeneOntologyBiologicalProcesspositive regulation of gene expression via chromosomal CpG island demethylation

TET2 TET3

4.18e-0415422GO:0044029
GeneOntologyBiologicalProcesspositive regulation of nuclear division

DAZ1 DAZ2 DAZ4

4.79e-0475423GO:0051785
GeneOntologyBiologicalProcessotic vesicle development

EYA1 PROX1

5.40e-0417422GO:0071599
GeneOntologyBiologicalProcessviral life cycle

PCSK5 VPS37C ILF3 CR2 PROX1

6.09e-04340425GO:0019058
GeneOntologyBiologicalProcessregulation of meiotic cell cycle

DAZ1 DAZ2 DAZ4

6.22e-0482423GO:0051445
GeneOntologyBiologicalProcessembryonic organ morphogenesis

NR4A3 EYA4 EYA1 PROX1 HOXA1

7.04e-04351425GO:0048562
GeneOntologyBiologicalProcessregulation of translational initiation

DAZ1 DAZ2 DAZ4

8.42e-0491423GO:0006446
GeneOntologyBiologicalProcessneuron fate commitment

EYA1 TBR1 PROX1

8.42e-0491423GO:0048663
GeneOntologyBiologicalProcessartery morphogenesis

EYA1 PROX1 HOXA1

8.69e-0492423GO:0048844
GeneOntologyBiologicalProcessembryonic organ development

PCSK5 NR4A3 EYA4 EYA1 PROX1 HOXA1

8.99e-04561426GO:0048568
GeneOntologyBiologicalProcessoocyte development

DAZ1 DAZ2 DAZ4

1.07e-0399423GO:0048599
GeneOntologyBiologicalProcessoocyte differentiation

DAZ1 DAZ2 DAZ4

1.21e-03103423GO:0009994
GeneOntologyBiologicalProcessmiddle ear morphogenesis

EYA4 EYA1

1.28e-0326422GO:0042474
GeneOntologyBiologicalProcesspositive regulation of cell cycle

NR4A3 DAZ1 DAZ2 DAZ4 PROX1

1.36e-03407425GO:0045787
GeneOntologyBiologicalProcesslate endosome to vacuole transport via multivesicular body sorting pathway

VPS37C HGS

1.38e-0327422GO:0032511
GeneOntologyBiologicalProcesscochlea morphogenesis

EYA1 HOXA1

1.59e-0329422GO:0090103
GeneOntologyBiologicalProcesspositive regulation of reproductive process

DAZ1 DAZ2 DAZ4

1.78e-03118423GO:2000243
GeneOntologyBiologicalProcessmultivesicular body assembly

VPS37C HGS

2.05e-0333422GO:0036258
GeneOntologyBiologicalProcessmultivesicular body organization

VPS37C HGS

2.18e-0334422GO:0036257
MousePhenoabnormal semicircular canal morphology

NR4A3 EYA1 FIGN HOXA1

9.42e-0659324MP:0002428
MousePhenoabnormal inner ear canal morphology

NR4A3 EYA1 FIGN HOXA1

1.23e-0563324MP:0002729
MousePhenoabnormal pelvic girdle bone morphology

CALCOCO2 PCSK5 EYA1 FIGN

4.41e-0587324MP:0004509
MousePhenoabnormal endolymphatic duct morphology

NR4A3 EYA1 HOXA1

4.69e-0531323MP:0006011
MousePhenoabsent cochlea

EYA1 HOXA1

7.57e-056322MP:0003147
MousePhenopostnatal lethality

TET2 RFX6 EYA4 FUS TBR1 HOXC13 FIGN CIC PROX1 HOXA1

1.00e-0410843210MP:0002082
MousePhenoabsent vestibular saccule

EYA1 HOXA1

1.06e-047322MP:0004315
MousePhenoabsent endolymphatic duct

EYA1 HOXA1

1.41e-048322MP:0000041
MousePhenoabnormal endocrine gland morphology

PCSK5 TET2 EWSR1 EYA4 FUS EYA1 TLL1 ANXA7 PROX1 HOXA1

1.57e-0411443210MP:0013560
MousePhenoabsent posterior semicircular canal

EYA1 HOXA1

1.81e-049322MP:0003163
MousePhenoabsent parathyroid glands

EYA1 HOXA1

1.81e-049322MP:0000680
MousePhenoabsent ovarian follicles

DAZ1 DAZ2 DAZ4

2.11e-0451323MP:0002777
MousePhenoabnormal thoracic aorta morphology

PCSK5 EYA1 TLL1 HOXA1

2.36e-04134324MP:0010468
MousePhenoabsent stapes

EYA1 HOXA1

2.76e-0411322MP:0004204
MousePhenoabnormal common crus morphology

EYA1 HOXA1

2.76e-0411322MP:0004922
MousePhenoabsent semicircular canals

FIGN HOXA1

3.30e-0412322MP:0000036
MousePhenoabsent lateral semicircular canal

EYA1 FIGN

3.90e-0413322MP:0003161
MousePhenoabnormal tympanic membrane morphology

EYA4 EYA1

3.90e-0413322MP:0006018
MousePhenosmall thymus

PCSK5 EWSR1 FUS TLL1 HOXA1

4.43e-04286325MP:0000706
MousePhenosmall otic vesicle

EYA1 HOXA1

5.23e-0415322MP:0004310
MousePhenointerrupted aortic arch, type b

EYA1 HOXA1

5.97e-0416322MP:0011659
MousePhenoabnormal tympanic cavity morphology

EYA4 EYA1

5.97e-0416322MP:0030154
MousePhenoabnormal superior semicircular canal morphology

EYA1 HOXA1

5.97e-0416322MP:0003069
MousePhenosmall ovary

DAZ1 EWSR1 DAZ2 DAZ4

6.92e-04178324MP:0001127
MousePhenolethality during fetal growth through weaning, incomplete penetrance

TET2 FUS EYA1 HOXC13 FIGN CIC TLL1 PROX1 HOXA1

6.99e-041124329MP:0011112
MousePhenoabnormal palate morphology

PCSK5 EYA4 EYA1 FIGN TLL1

7.49e-04321325MP:0003755
MousePhenoabnormal geniculate ganglion morphology

EYA1 HOXA1

7.59e-0418322MP:0001082
MousePhenoabsent middle ear ossicles

EYA1 HOXA1

7.59e-0418322MP:0000040
MousePhenoabnormal vestibular labyrinth morphology

NR4A3 EYA1 HOXA1

7.94e-0480323MP:0004427
MousePhenoabnormal otic vesicle development

EYA1 HOXA1

9.40e-0420322MP:0006030
MousePhenoabnormal parathyroid gland morphology

EYA1 HOXA1

9.40e-0420322MP:0000678
MousePhenoabnormal posterior semicircular canal morphology

EYA1 HOXA1

9.40e-0420322MP:0002858
MousePhenoabnormal thymus morphology

PCSK5 TET2 EWSR1 FUS EYA1 TLL1 HOXA1

9.91e-04717327MP:0000703
MousePhenoabnormal pterygoid process morphology

EYA1 FIGN

1.04e-0321322MP:0004452
MousePhenoabnormal lateral semicircular canal morphology

EYA1 FIGN

1.04e-0321322MP:0000037
MousePhenoabnormal otic capsule morphology

FIGN HOXA1

1.04e-0321322MP:0000039
MousePhenoabnormal ovarian follicle number

DAZ1 EWSR1 DAZ2 DAZ4

1.13e-03203324MP:0008871
MousePhenoretroesophageal right subclavian artery

EYA1 HOXA1

1.14e-0322322MP:0004160
MousePhenoabnormal middle ear morphology

EYA4 EYA1 HOXA1

1.19e-0392323MP:0000049
MousePhenoabnormal vestibulocochlear nerve morphology

EYA1 HOXA1

1.25e-0323322MP:0001072
MousePhenobidirectional circling

NR4A3 FIGN

1.36e-0324322MP:0001395
MousePhenoabnormal vestibular ganglion morphology

EYA1 HOXA1

1.36e-0324322MP:0002856
MousePhenostereotypic behavior

NR4A3 EYA1 FIGN HGS

1.37e-03214324MP:0001408
MousePhenodigestive/alimentary phenotype

PCSK5 RFX6 EYA4 EYA1 DMBT1 HOXC13 FIGN TLL1 HGS PROX1

1.38e-0315003210MP:0005381
MousePhenoabnormal aorta morphology

PCSK5 EYA1 TLL1 HOXA1

1.65e-03225324MP:0000272
MousePhenoabnormal ovary size

DAZ1 EWSR1 DAZ2 DAZ4

1.73e-03228324MP:0004853
MousePhenoarrest of spermatogenesis

DAZ1 DAZ2 DAZ4 SOX30

2.06e-03239324MP:0001155
MousePhenoabnormal suckling behavior

FUS ILF3 PROX1

2.15e-03113323MP:0001436
MousePhenofemale infertility

DAZ1 EWSR1 EYA1 DAZ2 DAZ4

2.22e-03410325MP:0001926
MousePhenoabnormal ovarian follicle morphology

DAZ1 EWSR1 DAZ2 DAZ4

2.25e-03245324MP:0001131
MousePhenoabnormal stapes morphology

EYA1 HOXA1

2.26e-0331322MP:0005107
MousePhenocircling

NR4A3 EYA1 FIGN

2.37e-03117323MP:0001394
MousePhenoabnormal semicircular canal ampulla morphology

EYA1 HOXA1

2.41e-0332322MP:0008488
MousePhenoabnormal glossopharyngeal ganglion morphology

EYA1 HOXA1

2.41e-0332322MP:0001096
MousePhenoabnormal aortic arch morphology

PCSK5 EYA1 HOXA1

2.49e-03119323MP:0004113
MousePhenoabnormal facial nerve morphology

EYA1 HOXA1

2.56e-0333322MP:0001071
MousePhenoaberrant origin of the right subclavian artery

EYA1 HOXA1

2.56e-0333322MP:0010465
MousePhenoabnormal tympanic ring morphology

EYA1 HOXA1

2.56e-0333322MP:0000030
MousePhenosmall pancreas

RFX6 PROX1

2.72e-0334322MP:0004247
MousePhenoabnormal malleus morphology

EYA1 HOXA1

2.72e-0334322MP:0000029
MousePhenoabnormal basicranium morphology

EYA1 FIGN HOXA1

2.74e-03123323MP:0010029
MousePhenoabnormal muscle morphology

EWSR1 ILF3 EYA1 HOXC13 TLL1 TLL2 HGS HOXA1

2.83e-031106328MP:0002108
MousePhenoabnormal membranous labyrinth morphology

NR4A3 EYA1 FIGN HOXA1

2.87e-03262324MP:0000035
MousePhenovascular ring

PCSK5 EYA1

2.88e-0335322MP:0010466
MousePhenoabnormal embryonic tissue morphology

PCSK5 NR4A3 EYA1 DMBT1 TBR1 CUBN HGS HOXA1

2.99e-031116328MP:0002085
MousePhenoabnormal otic vesicle morphology

EYA1 HOXA1

3.05e-0336322MP:0009806
MousePhenoabnormal female reproductive system physiology

DAZ1 EWSR1 FUS EYA1 DAZ2 DAZ4 ANXA7

3.13e-03876327MP:0003699
MousePhenoincreased mortality induced by gamma-irradiation

EWSR1 FUS

3.22e-0337322MP:0001658
MousePhenoabnormal aortic arch and aortic arch branch attachment

EYA1 HOXA1

3.22e-0337322MP:0010464
DomainCUB

CDCP2 DMBT1 CUBN CSMD2 TLL1 TLL2

9.96e-1049416PF00431
DomainCUB

CDCP2 DMBT1 CUBN CSMD2 TLL1 TLL2

1.13e-0950416SM00042
Domain-

CDCP2 DMBT1 CUBN CSMD2 TLL1 TLL2

1.44e-09524162.60.120.290
DomainCUB

CDCP2 DMBT1 CUBN CSMD2 TLL1 TLL2

1.62e-0953416PS01180
DomainCUB_dom

CDCP2 DMBT1 CUBN CSMD2 TLL1 TLL2

2.55e-0957416IPR000859
DomainPeptidase_M12A

MEP1B TLL1 TLL2

1.95e-076413IPR001506
DomainAstacin

MEP1B TLL1 TLL2

1.95e-076413PF01400
DomainRRM_1

DAZ1 EWSR1 FUS DAZ2 DAZ4 RBMS1

5.77e-06208416PF00076
DomainRRM

DAZ1 EWSR1 FUS DAZ2 DAZ4 RBMS1

7.35e-06217416SM00360
DomainRRM_dom

DAZ1 EWSR1 FUS DAZ2 DAZ4 RBMS1

9.51e-06227416IPR000504
DomainRRM

DAZ1 EWSR1 FUS DAZ2 DAZ4 RBMS1

1.02e-05230416PS50102
DomainBMP_1/tolloid-like

TLL1 TLL2

1.41e-053412IPR015446
Domain-

DAZ1 EWSR1 FUS DAZ2 DAZ4 RBMS1

1.43e-052444163.30.70.330
DomainNucleotide-bd_a/b_plait

DAZ1 EWSR1 FUS DAZ2 DAZ4 RBMS1

1.97e-05258416IPR012677
DomainEYA_fam

EYA4 EYA1

2.81e-054412IPR028472
DomainEYA_dom

EYA4 EYA1

2.81e-054412IPR006545
DomainZnMc

MEP1B TLL1 TLL2

3.45e-0529413SM00235
DomainPeptidase_Metallo

MEP1B TLL1 TLL2

3.45e-0529413IPR006026
DomainEGF

MEP1B PCSK5 CUBN TLL1 TLL2

1.57e-04235415SM00181
DomainEGF

MEP1B CUBN TLL1 TLL2

1.65e-04126414PF00008
DomainEGF-like_dom

MEP1B PCSK5 CUBN TLL1 TLL2

2.05e-04249415IPR000742
Domain-

EWSR1 FUS

2.09e-04104124.10.1060.10
DomainHMG_box_dom

CIC SOX30 PROX1

3.90e-0465413IPR009071
DomainMetalloPept_cat_dom

MEP1B TLL1 TLL2

7.44e-0481413IPR024079
Domain-

MEP1B TLL1 TLL2

7.44e-04814133.40.390.10
DomainEGF_CA

CUBN TLL1 TLL2

8.85e-0486413PF07645
Domainzf-RanBP

EWSR1 FUS

1.06e-0322412PF00641
DomainGalactose-bd-like

MEP1B PCSK5 GLB1L

1.15e-0394413IPR008979
DomainZnF_RBZ

EWSR1 FUS

1.16e-0323412SM00547
DomainZF_RANBP2_2

EWSR1 FUS

1.16e-0323412PS50199
DomainEGF_Ca-bd_CS

CUBN TLL1 TLL2

1.25e-0397413IPR018097
DomainZF_RANBP2_1

EWSR1 FUS

1.26e-0324412PS01358
DomainZINC_PROTEASE

MEP1B TLL1 TLL2

1.29e-0398413PS00142
DomainEGF_CA

CUBN TLL1 TLL2

1.33e-0399413PS01187
DomainZnf_RanBP2

EWSR1 FUS

1.37e-0325412IPR001876
DomainEGF-type_Asp/Asn_hydroxyl_site

CUBN TLL1 TLL2

1.62e-03106413IPR000152
DomainEGF_3

MEP1B CUBN TLL1 TLL2

1.72e-03235414PS50026
DomainEGF_1

MEP1B CUBN TLL1 TLL2

2.31e-03255414PS00022
DomainEGF_CA

CUBN TLL1 TLL2

2.42e-03122413SM00179
DomainEGF-like_CS

MEP1B CUBN TLL1 TLL2

2.51e-03261414IPR013032
DomainEGF-like_Ca-bd_dom

CUBN TLL1 TLL2

2.53e-03124413IPR001881
DomainEGF_2

MEP1B CUBN TLL1 TLL2

2.66e-03265414PS01186
DomainSushi

CSMD2 CR2

5.82e-0352412PF00084
DomainHomeodomain-like

TRERF1 HOXC13 PROX1 HOXA1

5.92e-03332414IPR009057
DomainHMG_box

CIC SOX30

6.04e-0353412PF00505
DomainHMG_BOX_2

CIC SOX30

6.26e-0354412PS50118
DomainHMG

CIC SOX30

6.26e-0354412SM00398
DomainCCP

CSMD2 CR2

6.26e-0354412SM00032
Domain-

CIC SOX30

6.49e-03554121.10.30.10
DomainSUSHI

CSMD2 CR2

6.72e-0356412PS50923
DomainSushi_SCR_CCP_dom

CSMD2 CR2

6.95e-0357412IPR000436
Domain-

PCSK5 GLB1L

1.12e-02734122.60.120.260
PathwayWP_MRNA_PROCESSING

DAZ1 EWSR1 FUS ILF3 DAZ2 DAZ4 RBMS1

5.50e-05451327MM15946
PathwayWP_OVARIAN_INFERTILITY

DAZ1 DAZ2 DAZ4

6.62e-0535323MM15948
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

TLL1 TLL2

5.15e-0415322M27161
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

DAZ1 EWSR1 CUBN DAZ2 DAZ4

5.39e-04301325MM15983
PathwayWP_MECP2_AND_ASSOCIATED_RETT_SYNDROME

TET2 FUS TET3

5.93e-0473323M39401
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

TLL1 TLL2

7.47e-0418322M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

TLL1 TLL2

7.47e-0418322MM14882
Pubmed

High frequency of DAZ1/DAZ2 gene deletions in patients with severe oligozoospermia.

DAZ1 DAZ2 DAZ4

1.64e-09342311870237
Pubmed

Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.

TET2 DAZ1 DAZ2 TET3 DAZ4

2.97e-094742532892421
Pubmed

Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.

DAZ1 DAZ2 DAZ4

6.54e-09442315066457
Pubmed

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

DAZ1 DAZ2 DAZ4

6.54e-0944237670487
Pubmed

Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair.

DAZ1 DAZ2 DAZ4

6.54e-09442311694340
Pubmed

The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly polymorphic in the DAZ repeat regions.

DAZ1 DAZ2 DAZ4

6.54e-0944239321470
Pubmed

Polymorphic expression of DAZ proteins in the human testis.

DAZ1 DAZ2 DAZ4

6.54e-09442319223287
Pubmed

Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome.

DAZ1 DAZ2 DAZ4

6.54e-09442311095434
Pubmed

Impact of partial DAZ1/2 deletion and partial DAZ3/4 deletion on male infertility.

DAZ1 DAZ2 DAZ4

6.54e-09442326232607
Pubmed

[Microdeletion of chromosome Y in male infertility: role of the DAZ gene].

DAZ1 DAZ2 DAZ4

6.54e-09442311688365
Pubmed

Polymorphic DAZ gene family in polymorphic structure of AZFc locus: Artwork or functional for human spermatogenesis?

DAZ1 DAZ2 DAZ4

6.54e-09442312752250
Pubmed

A novel approach for the analysis of DAZ gene copy number in severely idiopathic infertile men.

DAZ1 DAZ2 DAZ4

6.54e-09442311883873
Pubmed

Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

DAZ1 DAZ2 DAZ4

6.54e-09442310936047
Pubmed

[Study on DAZ gene copy deletion in severe oligozoospermia sperm donor for ICSI].

DAZ1 DAZ2 DAZ4

6.54e-09442316963411
Pubmed

Partial DAZ deletions in a family with five infertile brothers.

DAZ1 DAZ2 DAZ4

6.54e-09442312801575
Pubmed

Integration of H-2Z1, a somatosensory cortex-expressed transgene, interferes with the expression of the Satb1 and Tbc1d5 flanking genes and affects the differentiation of a subset of cortical interneurons.

DAZ1 TBR1 DAZ2 DAZ4

8.77e-092042422623674
Pubmed

Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.

DAZ1 DAZ2 DAZ4

1.63e-08542323579190
Pubmed

Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.

DAZ1 DAZ2 DAZ4

1.63e-08542322021443
Pubmed

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

DAZ1 DAZ2 DAZ4

1.63e-0854239288969
Pubmed

The dazzle in germ cell differentiation.

DAZ1 DAZ2 DAZ4

1.63e-08542320008336
Pubmed

Co-culture of spermatogonial stem cells with sertoli cells in the presence of testosterone and FSH improved differentiation via up-regulation of post meiotic genes.

DAZ1 DAZ2 DAZ4

1.63e-08542323456578
Pubmed

Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.

DAZ1 DAZ2 DAZ4

1.63e-0854238679003
Pubmed

In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.

DAZ1 DAZ2 DAZ4

1.63e-08542310903443
Pubmed

Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.

DAZ1 DAZ2 DAZ4

1.63e-0854239143498
Pubmed

Bisphenol A exposure modifies DNA methylation of imprint genes in mouse fetal germ cells.

DAZ1 DAZ2 DAZ4

1.63e-08542322699882
Pubmed

A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.

DAZ1 DAZ2 DAZ4

1.63e-0854238845845
Pubmed

DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice.

DAZ1 DAZ2 DAZ4

1.63e-08542311058556
Pubmed

AZFc partial deletions in Chilean men with severe spermatogenic failure.

DAZ1 DAZ2 DAZ4

1.63e-08542317416365
Pubmed

Dazl promotes germ cell differentiation from embryonic stem cells.

DAZ1 DAZ2 DAZ4

1.63e-08542319783541
Pubmed

Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway.

DAZ1 DAZ2 DAZ4

1.63e-08542322293198
Pubmed

DAZL protein expression in mouse preimplantation embryo.

DAZ1 DAZ2 DAZ4

1.63e-08542317761180
Pubmed

Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.

DAZ1 DAZ2 DAZ4

1.63e-08542319468308
Pubmed

Partial rescue of the Dazl knockout mouse by the human DAZL gene.

DAZ1 DAZ2 DAZ4

1.63e-08542312200456
Pubmed

Nature of the spermatogenic arrest in Dazl -/- mice.

DAZ1 DAZ2 DAZ4

1.63e-08542311514340
Pubmed

Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.

DAZ1 DAZ2 DAZ4

1.63e-08542311089564
Pubmed

Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.

DAZ1 DAZ2 DAZ4

1.63e-08542323298641
Pubmed

DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.

DAZ1 DAZ2 DAZ4

1.63e-08542322223682
Pubmed

A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.

DAZ1 DAZ2 DAZ4

1.63e-08542310393944
Pubmed

The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.

DAZ1 DAZ2 DAZ4

1.63e-0854238968756
Pubmed

A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.

DAZ1 DAZ2 DAZ4

1.63e-0854238968755
Pubmed

DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.

DAZ1 DAZ2 DAZ4

1.63e-08542330380414
Pubmed

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis.

DAZ1 DAZ2 DAZ4

1.63e-08542326411291
Pubmed

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

DAZ1 DAZ2 DAZ4

1.63e-08542323223451
Pubmed

Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression.

DAZ1 DAZ2 DAZ4

1.63e-08542334985827
Pubmed

Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.

DAZ1 DAZ2 DAZ4

1.63e-08542311804965
Pubmed

Expression profiling of the developing testis in wild-type and Dazl knockout mice.

DAZ1 DAZ2 DAZ4

1.63e-08542314648873
Pubmed

The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

DAZ1 DAZ2 DAZ4

1.63e-0854238896558
Pubmed

Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations.

DAZ1 DAZ2 DAZ4

1.63e-0854239700189
Pubmed

Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.

DAZ1 DAZ2 DAZ4

1.63e-08542321270429
Pubmed

Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.

DAZ1 DAZ2 DAZ4

1.63e-0854238661148
Pubmed

Expression profiles of the DAZ gene family in human testis with and without spermatogenic failure.

DAZ1 DAZ2 DAZ4

3.27e-08642315066460
Pubmed

DAZL binds to the transcripts of several Tssk genes in germ cells.

DAZ1 DAZ2 DAZ4

3.27e-08642318452650
Pubmed

A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

DAZ1 DAZ2 DAZ4

3.27e-08642324086306
Pubmed

DAZL binds to 3'UTR of Tex19.1 mRNAs and regulates Tex19.1 expression.

DAZ1 DAZ2 DAZ4

3.27e-08642319247806
Pubmed

DAZL is a master translational regulator of murine spermatogenesis.

DAZ1 DAZ2 DAZ4

3.27e-08642331355046
Pubmed

The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers.

DAZ1 DAZ2 DAZ4

3.27e-08642323417416
Pubmed

The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.

DAZ1 DAZ2 DAZ4

3.27e-08642332170089
Pubmed

Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells.

DAZ1 DAZ2 DAZ4

3.27e-08642316278232
Pubmed

Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment.

DAZ1 DAZ2 DAZ4

3.27e-08642320157580
Pubmed

A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.

DAZ1 DAZ2 DAZ4

3.27e-08642317219433
Pubmed

Mono-butyl phthalate-induced mouse testis injury is associated with oxidative stress and down-regulated expression of Sox9 and Dazl.

DAZ1 DAZ2 DAZ4

3.27e-08642328496037
Pubmed

DAZL regulates Tet1 translation in murine embryonic stem cells.

DAZ1 DAZ2 DAZ4

3.27e-08642326077710
Pubmed

The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

DAZ1 DAZ2 DAZ4

3.27e-08642316001084
Pubmed

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice.

DAZ1 DAZ2 DAZ4

3.27e-08642332962040
Pubmed

Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.

DAZ1 DAZ2 DAZ4

3.27e-08642317526644
Pubmed

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17.

DAZ1 DAZ2 DAZ4

3.27e-0864231869307
Pubmed

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

DAZ1 DAZ2 DAZ4

3.27e-08642311390979
Pubmed

BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells.

DAZ1 DAZ2 DAZ4

3.27e-08642327632217
Pubmed

The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.

DAZ1 DAZ2 DAZ4

3.27e-0864231638086
Pubmed

Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.

DAZ1 DAZ2 DAZ4

3.27e-08642314611632
Pubmed

Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1.

DAZ1 DAZ2 DAZ4

5.71e-08742310857750
Pubmed

The RNA-binding specificity of the mouse Dazl protein.

DAZ1 DAZ2 DAZ4

5.71e-08742311410654
Pubmed

Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.

DAZ1 DAZ2 DAZ4

5.71e-08742315081113
Pubmed

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.

DAZ1 DAZ2 DAZ4

5.71e-08742322699423
Pubmed

Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.

DAZ1 DAZ2 DAZ4

5.71e-08742311604102
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

DAZ1 DAZ2 DAZ4

5.71e-0874239588208
Pubmed

DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.

DAZ1 DAZ2 DAZ4

5.71e-08742326826184
Pubmed

Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.

DAZ1 DAZ2 DAZ4

5.71e-08742316946704
Pubmed

Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells.

DAZ1 DAZ2 DAZ4

9.13e-08842310951504
Pubmed

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

DAZ1 DAZ2 DAZ4

9.13e-08842332339196
Pubmed

Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination.

DAZ1 DAZ2 DAZ4

9.13e-08842333749946
Pubmed

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

DAZ1 DAZ2 DAZ4

9.13e-08842323204224
Pubmed

Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.

DAZ1 DAZ2 DAZ4

9.13e-08842329883445
Pubmed

A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.

DAZ1 DAZ2 DAZ4

9.13e-08842310823932
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

DAZ1 DAZ2 DAZ4

9.13e-08842322621333
Pubmed

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.

DAZ1 DAZ2 DAZ4

9.13e-08842332686646
Pubmed

A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men.

DAZ1 DAZ2 DAZ4

9.13e-08842311869379
Pubmed

Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.

DAZ1 DAZ2 DAZ4

1.37e-07942316310179
Pubmed

Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.

DAZ1 DAZ2 DAZ4

1.37e-07942320159962
Pubmed

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary.

DAZ1 DAZ2 DAZ4

1.37e-07942326378784
Pubmed

Embryoid bodies from mouse stem cells express oxytocin receptor, Oct-4 and DAZL.

DAZ1 DAZ2 DAZ4

1.37e-07942319695304
Pubmed

The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.

DAZ1 DAZ2 DAZ4

1.37e-07942328235998
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

DAZ1 EWSR1 FUS ILF3 DAZ2 DAZ4 RBMS1

1.85e-0734742716033648
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

DAZ1 DAZ2 DAZ4

1.95e-071042310601091
Pubmed

Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis.

DAZ1 DAZ2 DAZ4

1.95e-071042331234534
Pubmed

Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics.

EWSR1 FUS HNRNPUL1

1.95e-071042321956701
Pubmed

Tesmin transcription is regulated differently during male and female meiosis.

DAZ1 DAZ2 DAZ4

1.95e-071042314648882
Pubmed

MAX controls meiotic entry in sexually undifferentiated germ cells.

DAZ1 DAZ2 DAZ4

1.95e-071042338433229
Pubmed

Knockout mouse model and gametogenic failure.

DAZ1 DAZ2 DAZ4

1.95e-07104239922113
Pubmed

SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60.

DAZ1 DAZ2 DAZ4

1.95e-071042323810942
InteractionPITX1 interactions

RFX6 EWSR1 FAM168B TBR1 CIC HGS HOXA1

7.50e-09127427int:PITX1
InteractionMAPK1IP1L interactions

VPS37C EWSR1 EYA4 HNRNPUL1 HGS

3.53e-0845425int:MAPK1IP1L
InteractionHOXB9 interactions

CALCOCO2 PCSK5 TET2 FAM168B CIC HOXA1

2.10e-07124426int:HOXB9
InteractionSNRPC interactions

RFX6 EWSR1 EYA4 FUS ILF3 FAM168B HNRNPUL1 RBMS1 HOXA1

2.45e-07440429int:SNRPC
InteractionTLE5 interactions

CALCOCO2 PCSK5 VPS37C RFX6 EYA4 FAM168B TBR1 HGS HOXA1

2.59e-07443429int:TLE5
InteractionVPS37C interactions

VPS37C RFX6 ILF3 FAM168B HNRNPUL1 HGS

4.49e-07141426int:VPS37C
InteractionSCT interactions

MEP1B HGS HOXA1

7.01e-079423int:SCT
InteractionPEF1 interactions

CALCOCO2 VPS37C EWSR1 EYA4 HGS

2.92e-06108425int:PEF1
InteractionPAX9 interactions

VPS37C EWSR1 FIGN CIC HOXA1

7.26e-06130425int:PAX9
InteractionSNRPB interactions

CALCOCO2 RFX6 EWSR1 FUS ILF3 FAM168B CIC HOXA1

9.73e-06517428int:SNRPB
InteractionFAM168A interactions

CALCOCO2 VPS37C EWSR1 FAM168B HGS

1.12e-05142425int:FAM168A
InteractionPUM2 interactions

DAZ1 EYA4 DAZ2 DAZ4 RBMS1

1.19e-05144425int:PUM2
InteractionDAZL interactions

DAZ1 ILF3 HNRNPUL1 DAZ4 RBMS1

1.24e-05145425int:DAZL
InteractionATXN1L interactions

EYA4 FUS TBR1 CIC HGS

1.46e-05150425int:ATXN1L
InteractionOTX1 interactions

PCSK5 EWSR1 FAM168B CIC HOXA1

1.71e-05155425int:OTX1
InteractionSAXO4 interactions

RFX6 FAM168B HGS HOXA1

2.30e-0580424int:SAXO4
InteractionCSTF2 interactions

RFX6 EWSR1 FUS FAM168B HGS

2.31e-05165425int:CSTF2
InteractionUBAP2 interactions

VPS37C FUS FAM168B RBMS1 HGS

2.66e-05170425int:UBAP2
InteractionR3HDM1 interactions

EWSR1 EYA4 RBMS1 HOXA1

2.79e-0584424int:R3HDM1
InteractionPROSER1 interactions

EWSR1 EYA4 TBR1

3.63e-0531423int:PROSER1
InteractionHNF1B interactions

TET2 EWSR1 EYA4 TBR1 CIC

4.53e-05190425int:HNF1B
InteractionQKI interactions

DAZ1 EWSR1 EYA4 DAZ4 RBMS1

4.53e-05190425int:QKI
InteractionRAVER1 interactions

CALCOCO2 EYA4 FUS ILF3 RBMS1

5.00e-05194425int:RAVER1
InteractionRUNX1 interactions

VPS37C EWSR1 FUS DMBT1 CIC HGS

5.31e-05324426int:RUNX1
InteractionDBF4B interactions

PCSK5 FUS HOXA1

5.73e-0536423int:DBF4B
InteractionHNRNPUL1 interactions

VPS37C EWSR1 FUS ILF3 HNRNPUL1 RBMS1

8.26e-05351426int:HNRNPUL1
InteractionPAX8 interactions

TET2 HNRNPUL1 CIC ANXA7

8.30e-05111424int:PAX8
InteractionTBR1 interactions

TET2 TBR1 CIC HOXA1

8.90e-05113424int:TBR1
InteractionPLA2G10 interactions

PCSK5 VPS37C HGS HOXA1

8.90e-05113424int:PLA2G10
InteractionHGS interactions

CALCOCO2 VPS37C RFX6 FIGN CTTNBP2NL CIC HGS

9.34e-05523427int:HGS
InteractionZBTB7B interactions

EWSR1 FUS ILF3 HNRNPUL1 HOXC13 RBMS1

1.04e-04366426int:ZBTB7B
InteractionAGXT interactions

RFX6 FAM168B HOXA1

1.05e-0444423int:AGXT
InteractionTP53BP1 interactions

EWSR1 FUS ILF3 HNRNPUL1 CIC ANXA7 HGS

1.05e-04533427int:TP53BP1
InteractionFOXC1 interactions

EWSR1 ILF3 HNRNPUL1 HOXC13 CIC

1.07e-04228425int:FOXC1
InteractionRFX6 interactions

VPS37C RFX6 HGS

1.12e-0445423int:RFX6
InteractionEYA2 interactions

VPS37C EYA4 CIC HGS

1.16e-04121424int:EYA2
InteractionYPEL1 interactions

FUS CTTNBP2NL

1.18e-048422int:YPEL1
InteractionPSMB11 interactions

ILF3 HGS

1.18e-048422int:PSMB11
InteractionRPRD1B interactions

CALCOCO2 VPS37C EWSR1 FUS TPD52

1.19e-04233425int:RPRD1B
InteractionSIX4 interactions

EYA4 EYA1 CIC

1.20e-0446423int:SIX4
InteractionTLE3 interactions

TRERF1 TET2 TBR1 HOXC13 FIGN CIC

1.21e-04376426int:TLE3
InteractionPKNOX2 interactions

VPS37C CTTNBP2NL HGS

1.36e-0448423int:PKNOX2
InteractionEYA4 interactions

TET2 EWSR1 EYA4 EYA1 CIC

1.45e-04243425int:EYA4
InteractionSIX1 interactions

EYA4 EYA1 CIC

1.45e-0449423int:SIX1
InteractionNEDD8 interactions

CALCOCO2 EWSR1 FUS ILF3 HNRNPUL1 HGS

1.53e-04393426int:NEDD8
InteractionCUL5 interactions

EWSR1 FUS ILF3 HNRNPUL1 ANXA7 SOX30 TPD52

1.54e-04567427int:CUL5
InteractionCCNK interactions

RFX6 EYA4 FAM168B HOXA1

1.62e-04132424int:CCNK
InteractionPLEKHN1 interactions

CALCOCO2 RFX6 HOXA1

2.05e-0455423int:PLEKHN1
InteractionUBQLN2 interactions

CALCOCO2 VPS37C EWSR1 EYA4 FUS RBMS1 ANXA7 HGS

2.06e-04797428int:UBQLN2
InteractionCREBBP interactions

TRERF1 NR4A3 EWSR1 EYA4 FUS ANXA7 PROX1

2.16e-04599427int:CREBBP
InteractionGPS2 interactions

VPS37C EYA4 FAM168B HOXA1

2.27e-04144424int:GPS2
InteractionZNF503 interactions

EYA4 TBR1 HOXA1

2.28e-0457423int:ZNF503
InteractionKIAA0825 interactions

ILF3 HGS

2.30e-0411422int:KIAA0825
InteractionTET2 interactions

TET2 EYA4 TBR1 TET3

2.65e-04150424int:TET2
InteractionSPATA12 interactions

HGS HOXA1

2.76e-0412422int:SPATA12
InteractionFIGN interactions

FIGN HGS

2.76e-0412422int:FIGN
InteractionFBRSL1 interactions

EYA4 TBR1 RBMS1

2.78e-0461423int:FBRSL1
InteractionFLI1 interactions

EWSR1 FUS SOX30

2.92e-0462423int:FLI1
InteractionPITX2 interactions

EYA4 CIC HOXA1

2.92e-0462423int:PITX2
InteractionTCF7L2 interactions

NR4A3 EWSR1 FUS FAM168B TBR1

3.03e-04285425int:TCF7L2
InteractionCELF1 interactions

EWSR1 FUS ILF3 HNRNPUL1 RBMS1

3.18e-04288425int:CELF1
InteractionNKX2-4 interactions

TBR1 CIC

3.26e-0413422int:NKX2-4
InteractionTRIM31 interactions

CALCOCO2 EWSR1 EYA4 FUS ILF3 HNRNPUL1

3.34e-04454426int:TRIM31
InteractionDOCK2 interactions

CALCOCO2 PCSK5 HOXA1

3.52e-0466423int:DOCK2
InteractionDDX3X interactions

CALCOCO2 TET2 EWSR1 FUS ILF3 HNRNPUL1 CIC

3.58e-04651427int:DDX3X
InteractionESRRA interactions

FUS CIC PROX1

3.67e-0467423int:ESRRA
InteractionDDX1 interactions

EWSR1 FUS ILF3 HNRNPUL1 CIC RBMS1

3.70e-04463426int:DDX1
InteractionCREB5 interactions

PCSK5 EWSR1 CIC HOXA1

3.72e-04164424int:CREB5
InteractionSF1 interactions

EWSR1 EYA4 FUS ILF3 HNRNPUL1

4.07e-04304425int:SF1
InteractionSP7 interactions

TRERF1 TET2 EYA4 TBR1 CIC

4.07e-04304425int:SP7
InteractionDAZAP1 interactions

DAZ1 EWSR1 EYA4 RBMS1

4.17e-04169424int:DAZAP1
InteractionPPIA interactions

CALCOCO2 EWSR1 FUS ILF3 CTTNBP2NL CIC ANXA7 HGS

4.28e-04888428int:PPIA
InteractionPLSCR1 interactions

VPS37C EWSR1 ILF3 HOXA1

4.45e-04172424int:PLSCR1
InteractionTIAL1 interactions

VPS37C EYA4 FAM168B RBMS1

4.45e-04172424int:TIAL1
InteractionVGLL3 interactions

PCSK5 FAM168B HGS

4.54e-0472423int:VGLL3
InteractionCCDC33 interactions

CALCOCO2 PCSK5 HGS HOXA1

4.55e-04173424int:CCDC33
InteractionMAML1 interactions

EWSR1 EYA4 TBR1

4.73e-0473423int:MAML1
InteractionRBCK1 interactions

CALCOCO2 EYA1 HGS HOXA1

4.86e-04176424int:RBCK1
InteractionC11orf16 interactions

EWSR1 HOXA1

4.99e-0416422int:C11orf16
InteractionESRRG interactions

TRERF1 HGS PROX1

5.12e-0475423int:ESRRG
InteractionPRNP interactions

CALCOCO2 TBR1 CR2 ZC3H6 CIC ANXA7 HGS TPD52 HOXA1

5.28e-041158429int:PRNP
InteractionRCHY1 interactions

EWSR1 FUS ILF3 HNRNPUL1 HOXA1

5.51e-04325425int:RCHY1
InteractionDTX2 interactions

RFX6 EWSR1 EYA4 HGS HOXA1

5.91e-04330425int:DTX2
InteractionSMCP interactions

CALCOCO2 PCSK5 HOXA1

5.96e-0479423int:SMCP
InteractionDAZAP2 interactions

CALCOCO2 VPS37C DAZ1 HGS

5.98e-04186424int:DAZAP2
InteractionATN1 interactions

PCSK5 EWSR1 EYA4 HGS

6.10e-04187424int:ATN1
InteractionPSPC1 interactions

TET2 EWSR1 EYA4 FUS ILF3 TET3

6.50e-04515426int:PSPC1
InteractionNKX2-5 interactions

EWSR1 CIC PROX1

6.65e-0482423int:NKX2-5
InteractionPKNOX1 interactions

TET2 VPS37C HOXA1

6.65e-0482423int:PKNOX1
InteractionSF3B4 interactions

EWSR1 EYA4 FUS ILF3 HNRNPUL1

6.94e-04342425int:SF3B4
InteractionNEDD9 interactions

RFX6 FAM168B HOXA1

7.38e-0485423int:NEDD9
InteractionBCL9 interactions

EWSR1 EYA4 TBR1

7.64e-0486423int:BCL9
InteractionSIX3 interactions

NR4A3 EYA1

7.87e-0420422int:SIX3
InteractionPOLR2A interactions

CALCOCO2 EWSR1 FUS ILF3 EYA1 CIC

8.00e-04536426int:POLR2A
InteractionSORBS3 interactions

CALCOCO2 VPS37C HNRNPUL1 HGS

8.14e-04202424int:SORBS3
InteractionPRR12 interactions

EWSR1 EYA4 TBR1

8.17e-0488423int:PRR12
InteractionRNU1-1 interactions

EWSR1 FUS

8.68e-0421422int:RNU1-1
InteractionRBM45 interactions

EWSR1 FUS ILF3 HNRNPUL1

8.92e-04207424int:RBM45
InteractionTRAF4 interactions

CALCOCO2 PCSK5 HGS HOXA1

9.08e-04208424int:TRAF4
InteractionEEF1A1 interactions

TET2 FUS ILF3 HNRNPUL1 CIC ANXA7 HOXA1

9.13e-04762427int:EEF1A1
CytobandYq11.223

DAZ1 DAZ2 DAZ4

8.72e-0593423Yq11.223
CytobandEnsembl 112 genes in cytogenetic band chr2q24

TBR1 FIGN RBMS1

2.19e-04127423chr2q24
CytobandEnsembl 112 genes in cytogenetic band chrYq11

DAZ1 DAZ2 DAZ4

2.91e-03311423chrYq11
GeneFamilyBone morphogenetic proteins|Astacins

MEP1B TLL1 TLL2

8.22e-086303894
GeneFamilyRNA binding motif containing

DAZ1 EWSR1 FUS DAZ2 DAZ4 RBMS1

1.17e-06213306725
GeneFamilyEYA transcriptional coactivator and phosphatases

EYA4 EYA1

1.59e-0543021044
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

EWSR1 FUS

5.48e-042130289
GeneFamilyHOXL subclass homeoboxes

HOXC13 HOXA1

3.35e-0352302518
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD2 CR2

4.01e-03573021179
CoexpressionTESAR_JAK_TARGETS_MOUSE_ES_D3_DN

DAZ1 DAZ2 DAZ4

8.33e-0712423MM742
CoexpressionSASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN

DAZ1 DAZ2 DAZ4

8.33e-0712423MM781
CoexpressionWAGSCHAL_EHMT2_TARGETS_UP

DAZ1 DAZ2 DAZ4

6.63e-0623423MM1293
CoexpressionMADAN_DPPA4_TARGETS

MEP1B DAZ1 DAZ2 DAZ4

1.10e-0586424MM1312
CoexpressionMATZUK_SPERMATOGONIA

DAZ1 DAZ2 DAZ4

1.67e-0531423MM765
CoexpressionCHEN_ETV5_TARGETS_TESTIS

DAZ1 DAZ2 DAZ4

2.02e-0533423MM701
CoexpressionBENPORATH_EED_TARGETS

TET2 NR4A3 RFX6 EYA4 FAM168B TBR1 HOXC13 TLL1 HOXA1

3.71e-051059429M7617
CoexpressionBENPORATH_ES_WITH_H3K27ME3

TET2 NR4A3 RFX6 EYA4 TBR1 CSMD2 CR2 TLL1 HOXA1

5.54e-051115429M10371
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500

EYA4 ILF3 EYA1 ZC3H6 CTTNBP2NL TLL1 HOXA1

1.16e-05407417gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_100

NR4A3 EYA4 EYA1 TLL1

2.83e-0591414gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_100

NR4A3 EYA4 TLL1

3.50e-0533413gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_200

EYA4 EYA1 TLL1

4.56e-0536413gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200_k1
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TRERF1 CUBN FIGN PROX1

5.15e-06121424b2d571f571133c281d72584fe925cebbd2317829
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NR4A3 CR2 GLB1L PROX1

1.05e-05145424bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 NR4A3 RFX6 PROX1

2.63e-05183424d26c7b79895de28961b8d68351f28d4bb531c75c
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STPG1 TLL1 HGS PROX1

2.98e-051894240739baad9a7da511dd3d7249f84299aee88370a1
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_NE_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RFX6 DMBT1 TPD52 PROX1

3.10e-05191424f0a81f621e63e87ff62224b33cf0c71dfac1d6e2
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCSK5 RFX6 DMBT1 TPD52

3.64e-051994249d24223b571fba202455c5bd49bd79530abf09c0
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 NR4A3 EYA4 CTTNBP2NL

3.72e-0520042486f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellTCGA-Bile_Duct-Primary_Tumor|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

FUS ILF3 HNRNPUL1 HGS

3.72e-052004240350e5ffd36033099b7e32a1fdd790fff99790dc
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

FUS ILF3 HNRNPUL1 HGS

3.72e-05200424ad2a6da0b1ae7a9212a3c91e5eec4baa7481d8dc
ComputationalNeighborhood of ACP1

FUS ILF3 FAM168B HNRNPUL1 HGS

1.31e-04211265MORF_ACP1
ComputationalNeighborhood of UBE2I

FUS ILF3 FAM168B HNRNPUL1 HGS

2.29e-04238265MORF_UBE2I
Drugboron trichloride

DAZ1 DAZ2 DAZ4

1.16e-076423CID000025135
Drugpropham

DAZ1 DAZ2 DAZ4 RBMS1

1.29e-0644424CID000024685
DrugNor 3

NR4A3 EWSR1 FUS RBMS1

2.17e-0650424CID009578441
Drugdesmethylazelastine

DAZ1 DAZ2 DAZ4

3.21e-0616423CID000162558
Drugdazmegrel

DAZ1 DAZ2 DAZ4

5.54e-0619423CID000053555
DrugYM 026

DAZ1 DAZ2 DAZ4

5.54e-0619423CID000004443
Drugkt S

DAZ1 EWSR1 DAZ2 DAZ4

6.63e-0666424CID006399216
Drug5-Methylcytosine

TET2 TET3

9.95e-063422ctd:D044503
DrugAZFd

DAZ1 DAZ2 DAZ4

1.01e-0523423CID000196489
Drugdansylaziridine

DAZ1 DAZ2 DAZ4

1.01e-0523423CID000104008
Drugd-gluconhydroximo-1,5-lactam

DAZ1 DAZ2 DAZ4

2.53e-0531423CID000003479
Drug5-hydroxymethylcytosine

TET2 TET3

3.31e-055422ctd:C011865
DrugEMCs

NR4A3 EWSR1 FUS

3.36e-0534423CID005091655
Drug3-bromo-7-nitroindazole

DAZ1 DAZ2 DAZ4

3.99e-0536423CID000001649
DrugVistar

DAZ1 DAZ2 DAZ4

3.99e-0536423CID000040896
Drug2-chlorodideoxyadenosine

DAZ1 DAZ2 DAZ4

6.84e-0543423CID000072194
Drugmolybdenum disulfide

DAZ1 DAZ2 DAZ4

6.84e-0543423CID000014823
Drugridogrel

DAZ1 DAZ2 DAZ4

1.21e-0452423CID005362391
Drug2hd6

TRERF1 EYA4 EYA1

1.43e-0455423CID000462919
Drug5-aza-2'-deoxycytidine

DAZ1 EYA4 DMBT1 DAZ2 DAZ4 TLL1 PROX1

1.51e-04638427CID000016886
Drugazafagomine

DAZ1 DAZ2 DAZ4

1.59e-0457423CID011957435
Drugcamphene

PCSK5 EYA1

1.81e-0411422CID000006616
DrugRG-2

FUS ILF3 RBMS1

2.05e-0462423CID003070537
DrugNSC56408

DAZ1 DAZ2 DAZ4

2.05e-0462423CID000005604
DiseaseMale sterility due to Y-chromosome deletions

DAZ1 DAZ2 DAZ4

1.39e-078413C2931163
DiseasePartial chromosome Y deletion

DAZ1 DAZ2 DAZ4

1.39e-078413C1507149
Diseasecolon adenocarcinoma (is_marker_for)

PCSK5 TET2 ANXA7

5.61e-0625413DOID:234 (is_marker_for)
Diseaseamyotrophic lateral sclerosis type 6 (implicated_via_orthology)

EWSR1 FUS

5.65e-063412DOID:0060198 (implicated_via_orthology)
DiseaseExtraskeletal Myxoid Chondrosarcoma

NR4A3 EWSR1

1.88e-055412C1275278
Diseaseeye disease (implicated_via_orthology)

EYA4 EYA1

2.82e-056412DOID:5614 (implicated_via_orthology)
DiseaseFEV/FEC ratio

PCSK5 TET2 RFX6 MTMR11 EYA1 DMBT1 CTTNBP2NL RBMS1 SOX30

3.82e-051228419EFO_0004713
Diseasebranchiootorenal syndrome (implicated_via_orthology)

EYA4 EYA1

3.94e-057412DOID:14702 (implicated_via_orthology)
Diseasefrontotemporal dementia (implicated_via_orthology)

EWSR1 FUS

1.23e-0412412DOID:9255 (implicated_via_orthology)
Diseaseglucose measurement

TET2 RFX6 RBMS1 TPD52 PROX1

1.77e-04380415EFO_0004468
Diseasenasopharynx carcinoma (is_implicated_in)

TET2 CR2

1.96e-0415412DOID:9261 (is_implicated_in)
DiseaseSpermatogenic failure, Y-linked, 2

DAZ1 DAZ2

2.23e-0416412cv:C1839071
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

DAZ1 DAZ2

2.23e-0416412C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

DAZ1 DAZ2

2.23e-0416412415000
Diseasesmoking behavior, BMI-adjusted waist-hip ratio

EYA4 EYA1 HOXC13

2.35e-0486413EFO_0004318, EFO_0007788
Diseasewaist-hip ratio

PCSK5 TET2 EYA4 EYA1 HOXC13 FIGN RBMS1 PROX1

2.44e-041226418EFO_0004343
Diseasetriacylglycerol 50:1 measurement

PCSK5 EWSR1

6.47e-0427412EFO_0010408
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

EWSR1 FUS

7.99e-0430412DOID:332 (implicated_via_orthology)
Diseasegluteofemoral adipose tissue measurement

MTMR11 EYA1 HOXC13

8.24e-04132413EFO_0803317
Diseaseprimary dental caries

CUBN TLL1

1.03e-0334412EFO_0600095
Diseaseposterior thigh muscle fat infiltration measurement

EYA4 EYA1

1.09e-0335412EFO_0020934
DiseaseNeoplasm Recurrence, Local

TET2 TPD52

1.35e-0339412C0027643

Protein segments in the cluster

PeptideGeneStartEntry
TNTGLPGPATPAYSY

CTTNBP2NL

331

Q9P2B4
YGQTAYATSYGQPPT

EWSR1

61

Q01844
YATSYGQPPTGYTTP

EWSR1

66

Q01844
PQSSTGGYNQPSLGY

EWSR1

151

Q01844
GQSNYSYPQVPGSYP

EWSR1

166

Q01844
PPQTGSYSQAPSQYS

EWSR1

241

Q01844
GTVYSPGFPSPYSSS

CSMD2

2191

Q7Z408
GNFSSPQYPSSYPNN

CDCP2

266

Q5VXM1
GQESSFPPSGQYPYP

ANXA7

21

P20073
PAYPSSPFQVTTGYQ

DAZ2

361

Q13117
YPSSPFQVTTGYQLP

DAZ2

411

Q13117
FPAYPSSPFQVTTGY

DAZ2

456

Q13117
PAYPSSPFQVTTGYQ

DAZ2

481

Q13117
PTTAAIQNGFYPSPY

RBMS1

261

P29558
ATLPPNSPNGYYGSN

RFX6

791

Q8HWS3
SYPPQTAVGSGYSPG

FIGN

251

Q5HY92
YTPGYSQPPAGNSFN

MTMR11

496

A4FU01
SYPGYGQQPAPSSTS

FUS

96

P35637
YGTSVQPYSPTNEFP

PCSK5

596

Q92824
YGTSFSTPQPGQAPY

EYA1

166

Q99502
GPSYGSQNFSAPYSP

HOXA1

96

P49639
SFTSPGYPGTYPNNT

CUBN

3521

O60494
LYDGPNASSPSSGPY

CUBN

3571

O60494
PGQTPYSYQMPGSSF

EYA4

231

O95677
FPAYPSSPFQVTTGY

DAZ1

666

Q9NQZ3
FPYGTTVTYTCNPGP

CR2

546

P20023
PGSGQNYSGPPSSYQ

ILF3

861

Q12906
NYSGPPSSYQSSQGG

ILF3

866

Q12906
YPQAPSGPTFYSKTF

GLB1L

531

Q6UWU2
YGNPYSGIQESSSPS

CALCOCO2

376

Q13137
PPTSSSATLGYGYPF

HOXC13

111

P31276
FPAYPSSPFQVTTGY

DAZ4

501

Q86SG3
SGDFSSPFYPGNYPN

DMBT1

2016

Q9UGM3
IGSPNGTLYSPPFYS

MEP1B

441

Q16820
NPTFQTGYTPGTPYK

FAM168B

46

A1KXE4
SYSPARNPPGASTYN

HNRNPUL1

716

Q9BUJ2
AQYSPSPPGSSYAAQ

NR4A3

6

Q92570
LSNSSPQGYPTAGYP

TBR1

161

Q16650
SSPGFPNGYPSYTHC

TLL1

361

O43897
YPFQSPLGAPSGSFS

PROX1

491

Q92786
SSTCPYSRPPFGYGN

SOX30

626

O94993
SGPASYSGPKPSTQY

CIC

381

Q96RK0
FYTSASPPGPQFQGS

ZC3H6

451

P61129
LTSTGPGPGYYNPSD

STPG1

221

Q5TH74
QAGPTASPAYSSYQP

HGS

651

O14964
NFSAPGFPNGYPSYS

TLL2

361

Q9Y6L7
LPSFSYYGFPSSNPV

TET3

1281

O43151
YLYLSPSGNSSPPGS

TPD52

26

P55327
NCSPYLGSYSPQSQP

TET2

1641

Q6N021
VSQPSFYSGPLGPTY

VPS37C

231

A5D8V6
PPSYNPNPAASYSGA

TRERF1

666

Q96PN7