Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Znf_C2H2-like	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 YY2 ZNF429 ZNF251 ZNF585B GTF2IRD2B SALL2 ZNF394 ZNF347 GTF2IRD2 SP5 ZNF81 ZNF221 ZNF107 ZFP2	4.18e-06	796	172	22	IPR015880
Domain	-	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 YY2 ZNF429 ZNF251 ZNF585B SALL2 ZNF394 ZNF347 SP5 ZNF81 ZNF221 ZNF107 ZFP2	4.64e-06	679	172	20	3.30.160.60
Domain	ZnF_C2H2	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 YY2 ZNF429 ZNF251 ZNF585B GTF2IRD2B SALL2 ZNF394 ZNF347 GTF2IRD2 SP5 ZNF81 ZNF221 ZNF107 ZFP2	5.31e-06	808	172	22	SM00355
Domain	KRAB	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZNF154 ZFP30 ZNF429 ZNF251 ZNF585B ZNF394 ZNF347 ZNF81 ZNF221	6.03e-06	358	172	14	PS50805
Domain	Znf_C2H2/integrase_DNA-bd	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 YY2 ZNF429 ZNF251 ZNF585B SALL2 ZNF394 ZNF347 SP5 ZNF81 ZNF221 ZNF107 ZFP2	6.42e-06	694	172	20	IPR013087
Domain	KRAB	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZNF154 ZFP30 ZNF429 ZNF251 ZNF585B ZNF394 ZNF347 ZNF81 ZNF221	8.50e-06	369	172	14	SM00349
Domain	KRAB	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZNF154 ZFP30 ZNF429 ZNF251 ZNF585B ZNF394 ZNF347 ZNF81 ZNF221	8.77e-06	370	172	14	IPR001909
Domain	zf-C2H2	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 ZNF429 ZNF251 ZNF585B SALL2 ZNF394 ZNF347 SP5 ZNF81 ZNF221 ZNF107 ZFP2	2.22e-05	693	172	19	PF00096
Domain	KRAB	ZNF585A ZNF562 ZNF234 ZNF577 ZNF154 ZFP30 ZNF429 ZNF251 ZNF585B ZNF394 ZNF347 ZNF81 ZNF221	2.85e-05	358	172	13	PF01352
Domain	ZINC_FINGER_C2H2_2	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 YY2 ZNF429 ZNF251 ZNF585B SALL2 ZNF394 ZNF347 SP5 ZNF81 ZNF221 ZNF107 ZFP2	3.16e-05	775	172	20	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 YY2 ZNF429 ZNF251 ZNF585B SALL2 ZNF394 ZNF347 SP5 ZNF81 ZNF221 ZNF107 ZFP2	3.28e-05	777	172	20	PS00028
Domain	LamG	COL15A1 FAT3 LAMA5 CELSR2 AGRN	5.07e-05	44	172	5	SM00282
Domain	Znf_C2H2	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 YY2 ZNF429 ZNF251 ZNF585B SALL2 ZNF394 ZNF347 SP5 ZNF81 ZNF221 ZNF107 ZFP2	5.37e-05	805	172	20	IPR007087
Domain	Tyr_kinase_rcpt_2_CS	IGF1R ROS1 ALK	1.20e-04	11	172	3	IPR002011
Domain	RECEPTOR_TYR_KIN_II	IGF1R ROS1 ALK	1.59e-04	12	172	3	PS00239
Domain	Laminin_G	COL15A1 FAT3 LAMA5 CELSR2 AGRN	1.93e-04	58	172	5	IPR001791
Domain	LAM_G_DOMAIN	FAT3 LAMA5 CELSR2 AGRN	4.02e-04	38	172	4	PS50025
Domain	FacI_MAC	C7 AGRN	5.00e-04	4	172	2	IPR003884
Domain	-	GTF2IRD2B GTF2IRD2	5.00e-04	4	172	2	3.90.1460.10
Domain	GTF2I	GTF2IRD2B GTF2IRD2	5.00e-04	4	172	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	5.00e-04	4	172	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	5.00e-04	4	172	2	IPR004212
Domain	FIMAC	C7 AGRN	5.00e-04	4	172	2	SM00057
Domain	zf-C2H2_6	ZNF562 ZNF234 ZNF266 ZNF154 ZFP30 ZNF429 ZNF251 SALL2 ZNF107 ZFP2	6.80e-04	314	172	10	PF13912
Domain	DMAP_binding	GNPTAB DIP2C	8.28e-04	5	172	2	PF06464
Domain	ConA-like_dom	COL15A1 FAT3 LAMA5 ITGB4 ADGRG4 CELSR2 AGRN ALK	9.79e-04	219	172	8	IPR013320
Domain	-	SEMA3C RBBP5 STXBP5L IFT172 PALB2 SORT1 PIK3R4 UTP18 DNAI2 ATG16L2	1.06e-03	333	172	10	2.130.10.10
Domain	VWA	ITGA11 XRCC5 ITGB4 HMCN2 VWA5A	1.07e-03	84	172	5	SM00327
Domain	WD40/YVTN_repeat-like_dom	SEMA3C RBBP5 STXBP5L IFT172 PALB2 SORT1 PIK3R4 UTP18 DNAI2 ATG16L2	1.11e-03	335	172	10	IPR015943
Domain	DMAP1-bd	GNPTAB DIP2C	1.23e-03	6	172	2	IPR010506
Domain	Ribosomal_S6_kinase_II	RPS6KA2 RPS6KA3	1.23e-03	6	172	2	IPR016239
Domain	DMAP_binding	GNPTAB DIP2C	1.23e-03	6	172	2	SM01137
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF585A ZNF429 ZNF585B ZNF347 ZNF107 ZFP2	1.68e-07	49	174	6	9630514
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZNF585A SETD1B NSD2 RPS6KA2 PER1 LAMA5 PAPLN DENND1A ITGB4 NBPF1 RGMA IGF1R SLC12A4 CELSR2 KCNH2 DIP2C ZFYVE26 AGRN TBCD GAREM1	7.76e-07	1105	174	20	35748872
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CUL1 SETD1B HDAC6 MYO9A MYO19 BAG2 SRP54 RIOK3 SNX33 PRDX2 XRCC5 DUS3L GRSF1 HNRNPD PIK3R4 UTP18 OXCT1 NAT10 UGDH FHL2 QARS1 AGRN	1.24e-06	1353	174	22	29467282
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	SEMA3C COL15A1 LAMA5 PAPLN BGN HMCN2 VWA5A AGRN	2.15e-06	167	174	8	22159717
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ZNF487 HDAC6 ACAD9 RPS6KA3 ANGEL1 ZNF429 SRP54 XIAP CDCP1 DUS3L ITGB4 GRSF1 C2CD5 NAT10 TMEM131L PATJ AGRN VPS13B PML	2.38e-06	1084	174	19	11544199
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	HDAC6 USP9X LAMA5 RNF213 XIAP RIOK3 HNRNPD USP32 MORC3 UBASH3B AGRN PML	6.18e-06	481	174	12	28190767
Pubmed	Variants of folate metabolism genes and risk of left-sided cardiac defects.	TCN2 MTR NOS3	6.77e-06	8	174	3	19777601
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	CUL1 BAG2 RNF213 OXCT1 NAT10 MORC3 FHL2 PCCB PML	7.55e-06	262	174	9	36880596
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	STXBP5L ZFP30 SYNE2 DIP2C TMEM131L TBCD	1.30e-05	102	174	6	10231032
Pubmed	Genomic analysis of mouse retinal development.	CUL1 ZNF562 ZNF266 TTC9B ZNF429 PRDX2 PIK3R4 COQ10A SALL2 SV2B CELF3 CD59 PPIP5K1 ZFYVE26 UBASH3B OGA AGRN	1.33e-05	1006	174	17	15226823
Pubmed	Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.	RPS6KA2 RPS6KA3 GRSF1 UTP18 ALG5 NAT10 MORC3	1.70e-05	160	174	7	31678930
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	CUL1 RPS6KA2 RPS6KA3 BACE1 LAMA5 XIAP OSM IGF1R NOS3 PML	1.94e-05	371	174	10	25241761
Pubmed	Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.	TCN2 LIPF PRDX2 OXCT1 OGA NOS3	2.11e-05	111	174	6	21163940
Pubmed	Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.	SEMA3C KRT82 LAMA5 SP5	2.21e-05	33	174	4	18480165
Pubmed	Two-step colocalization of MORC3 with PML nuclear bodies.	MORC3 PML	2.49e-05	2	174	2	20501696
Pubmed	Effects of Advancing Gestation and Non-Caucasian Race on Ductus Arteriosus Gene Expression.	SLCO2A1 NOS3	2.49e-05	2	174	2	26265282
Pubmed	Clinical and prognostic implications of ALK and ROS1 rearrangements in never-smokers with surgically resected lung adenocarcinoma.	ROS1 ALK	2.49e-05	2	174	2	24462463
Pubmed	The junctional epithelium originates from the odontogenic epithelium of an erupted tooth.	LAMA5 ITGB4	2.49e-05	2	174	2	24785116
Pubmed	Restoration of mutant hERG stability by inhibition of HDAC6.	HDAC6 KCNH2	2.49e-05	2	174	2	29355491
Pubmed	Different clinical features between patients with ROS1-positive and ALK-positive advanced non-small cell lung cancer.	ROS1 ALK	2.49e-05	2	174	2	33583243
Pubmed	Immunocytochemical Detection of ALK and ROS1 Rearrangements in Lung Cancer Cytological Samples.	ROS1 ALK	2.49e-05	2	174	2	33683692
Pubmed	MYO9A deficiency in motor neurons is associated with reduced neuromuscular agrin secretion.	MYO9A AGRN	2.49e-05	2	174	2	29462312
Pubmed	Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells.	ROS1 ALK	2.49e-05	2	174	2	31392269
Pubmed	Simultaneous targeting of insulin-like growth factor-1 receptor and anaplastic lymphoma kinase in embryonal and alveolar rhabdomyosarcoma: a rational choice.	IGF1R ALK	2.49e-05	2	174	2	23867124
Pubmed	Expression of C-terminal ALK, RET, or ROS1 in lung cancer cells with or without fusion.	ROS1 ALK	2.49e-05	2	174	2	30943926
Pubmed	Astrocyte-induced cortical vasodilation is mediated by D-serine and endothelial nitric oxide synthase.	SRR NOS3	2.49e-05	2	174	2	23386721
Pubmed	USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma.	USP9X XIAP	2.49e-05	2	174	2	27317434
Pubmed	Crizotinib-Resistant ROS1 Mutations Reveal a Predictive Kinase Inhibitor Sensitivity Model for ROS1- and ALK-Rearranged Lung Cancers.	ROS1 ALK	2.49e-05	2	174	2	27401242
Pubmed	Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.	ZNF585A ZNF585B	2.49e-05	2	174	2	37668106
Pubmed	C2CD4A/B variants in the predisposition of lung cancer in the Chinese Han population.	C2CD4B C2CD4A	2.49e-05	2	174	2	35212842
Pubmed	Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.	C2CD4B C2CD4A	2.49e-05	2	174	2	33492421
Pubmed	Comparison of methods in the detection of ALK and ROS1 rearrangements in lung cancer.	ROS1 ALK	2.49e-05	2	174	2	25789833
Pubmed	ALK and ROS1 rearrangements tested by fluorescence in situ hybridization in cytological smears from advanced non-small cell lung cancer patients.	ROS1 ALK	2.49e-05	2	174	2	26152804
Pubmed	Crizotinib efficacy in advanced non-squamous NSCLC patients with ALK or ROS1 rearrangement.	ROS1 ALK	2.49e-05	2	174	2	34686712
Pubmed	A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.	C2CD4B C2CD4A	2.49e-05	2	174	2	29625024
Pubmed	Ketolysis is required for the proper development and function of the somatosensory nervous system.	OXCT1 AVIL	2.49e-05	2	174	2	37100111
Pubmed	Inactivation of BACE1 increases expression of endothelial nitric oxide synthase in cerebrovascular endothelium.	BACE1 NOS3	2.49e-05	2	174	2	35673977
Pubmed	MEK, ERK, and p90RSK are present on mitotic tubulin in Swiss 3T3 cells: a role for the MAP kinase pathway in regulating mitotic exit.	RPS6KA2 RPS6KA3	2.49e-05	2	174	2	11495723
Pubmed	BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin.	BACE1 SORT1	2.49e-05	2	174	2	21245145
Pubmed	Analysis of FANCB and FANCN/PALB2 fanconi anemia genes in BRCA1/2-negative Spanish breast cancer families.	PALB2 FANCB	2.49e-05	2	174	2	18302019
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	2.49e-05	2	174	2	15388857
Pubmed	Novel roles for LIX1L in promoting cancer cell proliferation through ROS1-mediated LIX1L phosphorylation.	LIX1L ROS1	2.49e-05	2	174	2	26310847
Pubmed	Ligation-dependent RT-PCR: a new specific and low-cost technique to detect ALK, ROS, and RET rearrangements in lung adenocarcinoma.	ROS1 ALK	2.49e-05	2	174	2	29251734
Pubmed	The four and a half LIM domain protein 2 interacts with and regulates the HERG channel.	KCNH2 FHL2	2.49e-05	2	174	2	18680509
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL15A1 LAMA5 BGN SERPINB9 HMCN2 VWA5A AGRN	3.03e-05	175	174	7	28071719
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LRP12 SEMA3C ITGA11 COL15A1 GNPTAB SPTLC1 KIAA1549 LAMA5 RNF213 PRDX2 ITGB4 BGN SORT1 IGF1R CELSR2 CD59 TMEM131L AGRN	3.60e-05	1201	174	18	35696571
Pubmed	MALDI-TOF MS genotyping of polymorphisms related to 1-carbon metabolism using common and mass-modified terminators.	TCN2 MTR NOS3	4.30e-05	14	174	3	18988749
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	HDAC6 NSD2 FAT3 BAG2 ANGEL1 SPTLC1 PER1 KIAA1549 RNF213 XIAP C2CD5 OSM SALL2 HMCN2 NAT10 MTR PML	4.91e-05	1116	174	17	31753913
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	COL15A1 LAMA5 PAPLN BGN AGRN	4.94e-05	79	174	5	18757743
Pubmed	ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.	ROS1 ALK	7.44e-05	3	174	2	29370427
Pubmed	ALK, ROS1 and RET rearrangements in lung squamous cell carcinoma are very rare.	ROS1 ALK	7.44e-05	3	174	2	26973202
Pubmed	Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.	RNF213 ALK	7.44e-05	3	174	2	12112524
Pubmed	ALK, ROS1 and RET fusions in 1139 lung adenocarcinomas: a comprehensive study of common and fusion pattern-specific clinicopathologic, histologic and cytologic features.	ROS1 ALK	7.44e-05	3	174	2	24629636
Pubmed	Beyond EGFR, ALK and ROS1: Current evidence and future perspectives on newly targetable oncogenic drivers in lung adenocarcinoma.	ROS1 ALK	7.44e-05	3	174	2	33053439
Pubmed	Activation of IGF-1R pathway and NPM-ALK G1269A mutation confer resistance to crizotinib treatment in NPM-ALK positive lymphoma.	IGF1R ALK	7.44e-05	3	174	2	31177400
Pubmed	FISH patterns of ROS1, MET, and ALK with a correlation of ALK immunohistochemistry in lung cancer: a case for introducing ALK immunohistochemistry 'Equivocal' interpretation category in the Ventana anti-ALK (D5F3) CDx assay - A tertiary cancer center experience.	ROS1 ALK	7.44e-05	3	174	2	33402590
Pubmed	Folate metabolizing gene polymorphisms and genetic vulnerability to preterm birth in Korean women.	TCN2 MTR	7.44e-05	3	174	2	34027569
Pubmed	Beta1 integrin and alpha-dystroglycan binding sites are localized to different laminin-G-domain-like (LG) modules within the laminin alpha5 chain G domain.	LAMA5 BGN	7.44e-05	3	174	2	12519075
Pubmed	Association of single nucleotide polymorphisms of MTHFR, TCN2, RNF213 with susceptibility to hypertension and blood pressure.	TCN2 RNF213	7.44e-05	3	174	2	31815282
Pubmed	Immunoexpression of BAP1, ROS1, and ALK in Spitzoid Melanocytic Tumors.	ROS1 ALK	7.44e-05	3	174	2	29623743
Pubmed	HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling.	HDAC6 AVIL	7.44e-05	3	174	2	36096670
Pubmed	Molecular characterization of inflammatory myofibroblastic tumors with frequent ALK and ROS1 gene fusions and rare novel RET rearrangement.	ROS1 ALK	7.44e-05	3	174	2	25723109
Pubmed	Associations Between MTR A2756G, MTRR A66G, and TCN2 C776G Polymorphisms and Risk of Nonsyndromic Cleft Lip With or Without Cleft Palate: A Meta-Analysis.	TCN2 MTR	7.44e-05	3	174	2	30004262
Pubmed	Development of lung adenocarcinomas with exclusive dependence on oncogene fusions.	ROS1 ALK	7.44e-05	3	174	2	25855381
Pubmed	Uterine inflammatory myofibroblastic tumor: First report of a ROS1 fusion.	ROS1 ALK	7.44e-05	3	174	2	34322931
Pubmed	Clinical characteristics of non-small cell lung cancer patients with EGFR mutations and ALK&ROS1 fusions.	ROS1 ALK	7.44e-05	3	174	2	35081265
Pubmed	Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning.	RPS6KA2 RPS6KA3	7.44e-05	3	174	2	12393804
Pubmed	Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility.	MTR NOS3	7.44e-05	3	174	2	17551576
Pubmed	Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.	ROS1 ALK	7.44e-05	3	174	2	34310819
Pubmed	Clinical outcomes with pemetrexed-based systemic therapies in RET-rearranged lung cancers.	ROS1 ALK	7.44e-05	3	174	2	27056998
Pubmed	Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase.	RPS6KA2 RPS6KA3	7.44e-05	3	174	2	12016217
Pubmed	Potential Unreliability of Uncommon ALK, ROS1, and RET Genomic Breakpoints in Predicting the Efficacy of Targeted Therapy in NSCLC.	ROS1 ALK	7.44e-05	3	174	2	33248323
Pubmed	A novel gene family induced by acute inflammation in endothelial cells.	C2CD4B C2CD4A	7.44e-05	3	174	2	15527968
Pubmed	The Clinical Implications of RSK1-3 in Human Breast Cancer.	RPS6KA2 RPS6KA3	7.44e-05	3	174	2	26977024
Pubmed	High prevalence of ROS1 gene rearrangement detected by FISH in EGFR and ALK negative lung adenocarcinoma.	ROS1 ALK	7.44e-05	3	174	2	32979347
Pubmed	A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.	C2CD4B C2CD4A	7.44e-05	3	174	2	20818381
Pubmed	Molecular and functional characterizations of the association and interactions between nucleophosmin-anaplastic lymphoma kinase and type I insulin-like growth factor receptor.	IGF1R ALK	7.44e-05	3	174	2	23730215
Pubmed	CELSR2-PSRC1-SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort.	SORT1 CELSR2	7.44e-05	3	174	2	24674750
Pubmed	A "liaison dangereuse" between AUF1/hnRNPD and the oncogenic tyrosine kinase NPM-ALK.	HNRNPD ALK	7.44e-05	3	174	2	16835382
Pubmed	A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.	C2CD4B C2CD4A	7.44e-05	3	174	2	21799836
Pubmed	Comprehensive analysis of ALK, ROS1 and RET rearrangements in locally advanced rectal cancer.	ROS1 ALK	7.44e-05	3	174	2	33168793
Pubmed	Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.	LAMA5 ITGB4	7.44e-05	3	174	2	15316072
Pubmed	IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells.	IGF1R ALK	7.44e-05	3	174	2	19423729
Pubmed	The impact of eNOS, MTR and MTHFR polymorphisms on renal graft survival in children and young adults.	MTR NOS3	7.44e-05	3	174	2	19349296
Pubmed	Cost-effectiveness analysis comparing companion diagnostic tests for EGFR, ALK, and ROS1 versus next-generation sequencing (NGS) in advanced adenocarcinoma lung cancer patients.	ROS1 ALK	7.44e-05	3	174	2	32928143
Pubmed	Association of variants in CELSR2-PSRC1-SORT1 with risk of serum lipid traits, coronary artery disease and ischemic stroke.	SORT1 CELSR2	7.44e-05	3	174	2	26464717
Pubmed	Bidirectional role of orphan nuclear receptor RORalpha in clock gene transcriptions demonstrated by a novel reporter assay system.	PER1 RORA	7.44e-05	3	174	2	15135064
Pubmed	The methionine synthase polymorphism c.2756A>G alters susceptibility to glioblastoma multiforme.	TCN2 MTR	7.44e-05	3	174	2	17119065
Pubmed	Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.	C2CD4B C2CD4A	7.44e-05	3	174	2	27329800
Pubmed	Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors.	SERPINB8 SERPINB9	7.44e-05	3	174	2	8530382
Pubmed	Expression levels of ROS1/ALK/c-MET and therapeutic efficacy of cetuximab plus chemotherapy in advanced biliary tract cancer.	ROS1 ALK	7.44e-05	3	174	2	27136744
Pubmed	B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors.	ZNF562 ZNF266	7.44e-05	3	174	2	36717582
Pubmed	EGFR mutations and ROS1 and ALK rearrangements in a large series of non-small cell lung cancer in South India.	ROS1 ALK	7.44e-05	3	174	2	32881404
Pubmed	Circadian genes and risk of prostate cancer: Findings from the EPICAP study.	PER1 RORA	7.44e-05	3	174	2	30665264
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	7.44e-05	3	174	2	15100712
Pubmed	[Clinicopathological significance in non-small cell lung cancer with mutations and co-mutations of EGFR, ALK and ROS1].	ROS1 ALK	7.44e-05	3	174	2	33677892
Pubmed	ALK and ROS1 testing on lung cancer cytologic samples: Perspectives.	ROS1 ALK	7.44e-05	3	174	2	28743163
Pubmed	Lactate dehydrogenase is an AU-rich element-binding protein that directly interacts with AUF1.	LDHAL6B HNRNPD	7.44e-05	3	174	2	12107167
Pubmed	A long noncoding RNA associated with susceptibility to celiac disease.	IL18RAP HNRNPD	7.44e-05	3	174	2	27034373
Pubmed	Functional coding/non-coding variants in EGFR, ROS1 and ALK genes and their role in liquid biopsy as a personalized therapy.	ROS1 ALK	7.44e-05	3	174	2	33038629
Cytoband	15q22.2	C2CD4B LDHAL6B C2CD4A RORA	4.40e-06	29	174	4	15q22.2
Cytoband	Xp22.2-p22.1	RPS6KA3 YY2	1.42e-04	5	174	2	Xp22.2-p22.1
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF585A ZNF562 ZNF234 ZNF577 ZNF266 ZBTB17 ZNF154 ZFP30 YY2 ZNF429 ZNF251 ZNF585B SALL2 ZNF394 ZNF347 SP5 ZNF81 ZNF221 ZNF107 ZFP2	7.87e-08	718	123	20	28
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	LCA5L OAS2 DENND1A ITGB4 CDC14A OSM DNAI2 MTR DLEC1 C7 CFAP46	3.97e-11	160	174	11	6de505bfe1fbbe984718740a9cf43d0e02ff452e
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SEMA3C ITGA11 ASIC2 BGN KCNH2 SLCO2A1 UBASH3B FHL2	7.54e-07	187	174	8	387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Endothelial-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	C2CD4B COL15A1 LAMA5 ITGB4 SLCO2A1 SYNE2 C7 NOS3	1.12e-06	197	174	8	f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	C2CD4B COL15A1 LAMA5 ITGB4 SLCO2A1 SYNE2 C7 NOS3	1.12e-06	197	174	8	1a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C2CD4B COL15A1 LAMA5 ITGB4 SLCO2A1 SYNE2 C7 NOS3	1.12e-06	197	174	8	96d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MUC21 MYO9A SMCO1 IL18RAP ADGRG4 SYNE2 CFAP46	1.16e-06	137	174	7	761cc0e2b4971e98f6d0691d4575b5cd208b602d
ToppCell	distal-2-Endothelial-Vein\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C2CD4B ITGB4 CAPN11 ITPKC SLCO2A1 CD59 C7 NOS3	1.25e-06	200	174	8	2785225956d2422acab90e99b7debe3709cf3308
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA3C ASIC2 FAT3 PRDX2 CRYBA2 OXCT1 ATP6V0A4	3.53e-06	162	174	7	9a18286e361e1dd18e6f943ce27db58b199fb6e4
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA3C ASIC2 FAT3 PRDX2 CRYBA2 OXCT1 ATP6V0A4	3.53e-06	162	174	7	3395e4dffdb9304d157c325e1fc0f12b433c7bd3
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA3C ASIC2 FAT3 PRDX2 CRYBA2 OXCT1 ATP6V0A4	3.53e-06	162	174	7	9522af31f6b2f3cb81b6b84bd08353eea504d1d6
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA3C ASIC2 FAT3 PRDX2 CRYBA2 OXCT1 ATP6V0A4	3.53e-06	162	174	7	40265af9b36fd144a8577b8dacccd4fc0888a593
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_1\|Classical_Monocyte / Disease condition and Cell class	CRACR2A EIF2S3B SLC44A5 SYNE2 PATJ OGA GAREM1	4.49e-06	168	174	7	d50078614f7af74dc2aa4081c1708a5156ac51cf
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRR TMEM104 NBPF1 CELSR2 SLC44A5 FHL2 ABCG5	5.04e-06	171	174	7	effcc4b6d26eafc2ca6fa08b6fee2689eff48f0f
ToppCell	MS-CD8-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	ZNF577 RPS6KA2 SRR TMEM104 HELB GTF2IRD2B MORC3	5.24e-06	172	174	7	0b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	MRC1 TCN2 MYO9A PER1 SORT1 TMEM131L NOS3	5.44e-06	173	174	7	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ITGA11 EMB KIAA1549 SLC44A5 CNTN5 SNTG1 ROS1	5.44e-06	173	174	7	8335b77f730ed43fc348a005566e73a103c6774b
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C2CD4B STXBP5L KIAA1549 ADGRG4 CRYBA2 CELF3 ROS1	6.80e-06	179	174	7	f2e8fc975c30992611630197b79daaeef7c4211d
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	GNPTAB GRSF1 SORT1 UTP18 USP32 DIP2C PPIP5K1	7.32e-06	181	174	7	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	C2CD4B EMB PRDX2 TMEM156 KCNH2 SYNE2 RORA	7.86e-06	183	174	7	317b756378a9efd8ecb754acf7273f83f996e106
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 LRP12 LIPF SORT1 MTMR7 DIP2C PATJ	8.14e-06	184	174	7	8fa30789c9d583188667cf375d2218e392dd40bc
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDC14A HELB IGF1R SYNE2 MTR RORA PATJ	8.14e-06	184	174	7	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 LRP12 LIPF SORT1 MTMR7 DIP2C PATJ	8.44e-06	185	174	7	4bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCell	droplet-Lung-nan-18m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 LRP12 LIPF SORT1 MTMR7 DIP2C PATJ	9.05e-06	187	174	7	f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCell	droplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 LRP12 LIPF SORT1 MTMR7 DIP2C PATJ	9.05e-06	187	174	7	f20e7a1751694390f535ffb27b97e887220f8695
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PER1 PRDX2 CDC14A OSM SYNE2 RORA PATJ	9.37e-06	188	174	7	3e3055dacc05a932f2beb114babf1dc76994e1af
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 LRP12 LIPF SORT1 MTMR7 DIP2C PATJ	9.70e-06	189	174	7	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 LRP12 LIPF SORT1 MTMR7 DIP2C PATJ	9.70e-06	189	174	7	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEMA3C ITGA11 ASIC2 BGN SLCO2A1 UBASH3B FHL2	9.70e-06	189	174	7	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDC14A HELB IGF1R SYNE2 MTR RORA PATJ	1.04e-05	191	174	7	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PER1 CDC14A HELB SYNE2 MTR RORA PATJ	1.04e-05	191	174	7	142f98cabf8737b28369315b3d7a0797ded88e03
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DENND1A IGF1R SYNE2 DIP2C RORA PATJ VPS13B	1.07e-05	192	174	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IGF1R ATP6V0A4 MTR DIP2C RORA PATJ GAREM1	1.11e-05	193	174	7	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EMB IL18RAP CDC14A HELB TMEM156 OXCT1 SYNE2	1.15e-05	194	174	7	3d6f2d190dd50804afea299957cc44c2bb756134
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ASIC2 MYO9A RNF213 SLC44A5 SYNE2 PATJ GAREM1	1.15e-05	194	174	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	ITGA11 COL15A1 BGN RGMA HMCN2 RORA C7	1.15e-05	194	174	7	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 COL15A1 TRPC4 BGN TMEM131L C7 FHL2	1.19e-05	195	174	7	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	PAPLN ITGB4 RGMA SERPINB9 SLC12A4 VWA5A FHL2	1.19e-05	195	174	7	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	critical-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	EMB RPS6KA3 RNF213 IL18RAP SYNE2 RORA TBCD	1.23e-05	196	174	7	c861f017aa9050282aa81c5a445bae399df00e4f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 COL15A1 FAT3 TRPC4 HMCN2 CNTN5 FHL2	1.23e-05	196	174	7	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3C ITGA11 COL15A1 TRPC4 BGN C7 FHL2	1.23e-05	196	174	7	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3C ITGA11 COL15A1 TRPC4 BGN C7 FHL2	1.23e-05	196	174	7	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	healthy_donor-Lymphocytic-T_cell-Gamma_Delta_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	EMB RPS6KA3 IL18RAP CDC14A SYNE2 RORA PATJ	1.23e-05	196	174	7	6eabbac1625f715531bae562a28da27664572600
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 COL15A1 FAT3 TRPC4 HMCN2 CNTN5 FHL2	1.23e-05	196	174	7	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EMB RPS6KA2 ITGB4 CDC14A SLCO2A1 SP5 NOS3	1.23e-05	196	174	7	dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FAT3 ANGEL1 BGN PIK3R4 SLC12A4 AVIL USP32	1.27e-05	197	174	7	d7cef7881abd807a679432766ced609a6efd1067
ToppCell	Tracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FAT3 ANGEL1 BGN PIK3R4 SLC12A4 AVIL USP32	1.27e-05	197	174	7	20a5958512bdb99daeb8f4d244df53e4f048f879
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Basal_1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	ASIC2 FAT3 PRDX2 ITGB4 KCNH2 ATP6V0A4 FHL2	1.31e-05	198	174	7	f632342e1e8911dd82b5df171776a84c7dc3f931
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 COL15A1 TRPC4 BGN TMEM131L C7 FHL2	1.31e-05	198	174	7	79576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GNPTAB RNF213 CDC14A HELB SYNE2 RORA VPS13B	1.35e-05	199	174	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EMB RPS6KA3 RNF213 IL18RAP CDC14A SYNE2 RORA	1.35e-05	199	174	7	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	RNF213 OAS2 HELB TMEM156 SYNE2 RORA ZNF107	1.35e-05	199	174	7	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	COVID-19_Severe-MAIT\|World / disease group, cell group and cell class	ZNF585A IL18RAP CDC14A ZNF585B RORA DLEC1	2.29e-05	145	174	6	8d63f97812f63329ef9c940b291dc5a1c4d90690
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	EMB FAT3 IL18RAP SORT1 SV2B GAREM1	2.47e-05	147	174	6	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	COVID-19_Severe-MAIT\|COVID-19_Severe / disease group, cell group and cell class	ZNF585A IL18RAP CDC14A SYNE2 RORA DLEC1	2.77e-05	150	174	6	923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EMB OAS2 IL18RAP OSM IGF1R ZFYVE26	2.77e-05	150	174	6	6e806a028c0519489151c181d9907e05289e27e0
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	EMB CDC14A HELB SYNE2 RORA PATJ	2.87e-05	151	174	6	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ASIC2 LCA5L BGN C7 FHL2 AGRN	3.58e-05	157	174	6	beab0ac47202266b04543c02cfcdda012375e879
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SMCO1 SERPINB8 CELSR2 ALG5 ZNF221 C7	3.84e-05	159	174	6	330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	STXBP5L FAT3 CNTN5 SNTG1 MYO18B ALK	3.84e-05	159	174	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SMCO1 SERPINB8 CELSR2 ALG5 ZNF221 C7	3.84e-05	159	174	6	cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_P4HA3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ITGA11 COL15A1 CDC14A RGMA GUCA1C ROS1	4.26e-05	162	174	6	dd4a08af653095ad4f63112312715589a1d43b38
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO9A SMCO1 YY2 TMEM104 SORT1 FANCB	4.41e-05	163	174	6	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO9A SMCO1 YY2 TMEM104 SORT1 FANCB	4.41e-05	163	174	6	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZBTB17 CRACR2A ANGEL1 RGMA KCNH2 ATP6V0A4	5.05e-05	167	174	6	49d9220f22d10ff06c0512c9c40c26ad51728e4f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDC14A TMEM156 SYNE2 RORA PATJ OGA	5.05e-05	167	174	6	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZBTB17 CRACR2A ANGEL1 RGMA KCNH2 ATP6V0A4	5.05e-05	167	174	6	7ec032a98a13504d15c7e3a4e259278d07f40180
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZBTB17 CRACR2A ANGEL1 RGMA KCNH2 ATP6V0A4	5.05e-05	167	174	6	5e3588eee73693a996bb4846427cf0038ceafbca
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA3C ITGA11 CDC14A RGMA VWA5A ROS1	5.22e-05	168	174	6	217770a94ace446cdfc7687b459dece707576e76
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	PAPLN SRR ITPKC ALG5 C7 FHL2	5.39e-05	169	174	6	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 SRP54 SRR SNX33 DUS3L DNAAF3	5.39e-05	169	174	6	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	STXBP5L MTMR7 SV2B KCNH2 CELF3 SNTG1	5.39e-05	169	174	6	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	COVID-19-lung-MAST\|lung / Disease (COVID-19 only), tissue and cell type	GNPTAB KIAA1549 NDEL1 KCNH2 VWA5A DIP2C	5.57e-05	170	174	6	e90f18e5462381b38e918442b38b1c8105291908
ToppCell	Basal_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	C2CD4B C2CD4A ITGB4 NBPF1 KCNH2 FHL2	5.57e-05	170	174	6	776d4224a682b6c648041827efd69794f88906f0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA3C ASIC2 RGMA SV2B VWA5A ROS1	6.34e-05	174	174	6	e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4\|TCGA-Lung / Sample_Type by Project: Shred V9	ITGA11 MUC21 COL15A1 EMB RNF213 ARHGAP20	6.75e-05	176	174	6	0923b01137d6f9956ca815b41102c81e82624065
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCN2 YY2 OAS2 SLCO2A1 C7 NOS3	6.97e-05	177	174	6	1921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCell	facs-Lung-EPCAM-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C TCN2 LAMA5 OAS2 FANCB SLCO2A1	6.97e-05	177	174	6	2433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 RPS6KA2 OAS2 RGMA OSM AVIL	7.19e-05	178	174	6	09a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EMB RPS6KA3 PER1 CDC14A SYNE2 RORA	7.41e-05	179	174	6	b0585a8e596c3d8e434af943e65207fa5877600d
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STXBP5L ADGRG4 CRYBA2 CELF3 SNTG1 ROS1	7.64e-05	180	174	6	6b1606238417490e0d9930870a7827419d1c3737
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 COL15A1 FAT3 TRPC4 BGN C7	7.88e-05	181	174	6	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RNF213 CDC14A SYNE2 TMEM131L RORA OGA	7.88e-05	181	174	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA11 COL15A1 FAT3 TRPC4 BGN C7	7.88e-05	181	174	6	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Deuterosomal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	LCA5L DNAAF3 DNAI2 DLEC1 IQUB CFAP46	8.12e-05	182	174	6	000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	OAS2 EIF2S3B NBPF1 TMEM131L PATJ OGA	8.12e-05	182	174	6	877b6e611626628e709568747512f2827ebb2795
ToppCell	Basal\|World / shred by cell class for mouse tongue	SEMA3C LAMA5 ITGB4 SLC12A4 UGDH AGRN	8.37e-05	183	174	6	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EMB RPS6KA2 ITGB4 CDC14A AGRN NOS3	8.37e-05	183	174	6	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCN2 LAMA5 SLCO2A1 CD59 C7 NOS3	8.37e-05	183	174	6	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 LRP12 LIPF SORT1 MTMR7 PATJ	8.63e-05	184	174	6	15ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CDC14A NBPF1 SYNE2 MTR RORA PATJ	8.63e-05	184	174	6	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 TRPC4 ADGRG4 C7 ARHGAP20 FHL2	8.63e-05	184	174	6	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRC1 LRP12 LIPF SORT1 MTMR7 PATJ	8.63e-05	184	174	6	bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ITGA11 COL15A1 RGMA HMCN2 RORA C7	8.89e-05	185	174	6	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC4 VWA5A SP5 TMEM131L UBASH3B ALK	8.89e-05	185	174	6	e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 RNF213 CELSR2 ROS1 FHL2 AGRN	8.89e-05	185	174	6	a6874dd3030d04380cc3c01de1069461aad4ef45
ToppCell	Ciliated_cells-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	LCA5L DNAAF3 CNTN5 DNAI2 DLEC1 CFAP46	9.16e-05	186	174	6	f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 LRP12 LIPF SORT1 MTMR7 PATJ	9.16e-05	186	174	6	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 LRP12 LIPF SORT1 MTMR7 PATJ	9.16e-05	186	174	6	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LCA5L DNAAF3 DNAI2 DLEC1 IQUB CFAP46	9.16e-05	186	174	6	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A SLC44A5 SYNE2 DIP2C PATJ FHL2	9.16e-05	186	174	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
Disease	Malignant neoplasm of breast	NSD2 RPS6KA3 TRPC4 SPTLC1 YY2 LDHAL6B PER1 PALB2 BGN PIK3R4 IGF1R SYNE2 MTR DIP2C ZFYVE26 DLEC1 FHL2 ALK NOS3 VPS13B	3.16e-06	1074	167	20	C0006142
Disease	1-stearoylglycerol 1-monostearin measurement	KIAA1549 SYNE2	3.18e-05	2	167	2	EFO_0021111
Disease	four-jointed box protein 1 measurement	GNPTAB CELSR2	9.52e-05	3	167	2	EFO_0801605
Disease	Fetal Growth Retardation	NSD2 IGF1R NOS3	1.89e-04	20	167	3	C0015934
Disease	Coffin-Lowry syndrome (implicated_via_orthology)	RPS6KA2 RPS6KA3	1.90e-04	4	167	2	DOID:3783 (implicated_via_orthology)
Disease	sortilin measurement	SORT1 CELSR2	1.90e-04	4	167	2	EFO_0600000
Disease	hemojuvelin measurement	RGMA CELSR2	3.15e-04	5	167	2	EFO_0008148
Disease	Pancytopenia	TCN2 PALB2 FANCB	4.21e-04	26	167	3	C0030312
Disease	Liver Cirrhosis, Experimental	EMB SRR BGN COQ10A OSM MTMR7 SERPINB9 AFM C7 FHL2 TMEM184B NOS3 ABCG5	4.87e-04	774	167	13	C0023893
Disease	waist-hip ratio	SEMA3C ITGA11 C2CD4B COL15A1 RIOK3 OSM IGF1R UTP18 CNTN5 SYNE2 RORA DLEC1 POC5 PATJ PCCB IQUB PML	6.16e-04	1226	167	17	EFO_0004343
Disease	sleep duration, high density lipoprotein cholesterol measurement	DHX8 RGMA SLC12A4 CELSR2 ATP6V0A4	6.41e-04	121	167	5	EFO_0004612, EFO_0005271
Disease	lysosomal protective protein measurement	GNPTAB TMEM131L	6.56e-04	7	167	2	EFO_0008215
Disease	centronuclear myopathy (implicated_via_orthology)	MTMR7 MTM1	6.56e-04	7	167	2	DOID:14717 (implicated_via_orthology)
Disease	total cholesterol measurement, C-reactive protein measurement	CELSR2 RORA ABCG5	7.12e-04	31	167	3	EFO_0004458, EFO_0004574
Disease	Mental Retardation, X-Linked 1	USP9X RPS6KA3 ZNF81	7.83e-04	32	167	3	C2931498
Disease	cortical surface area change measurement	SV2B CNTN5	8.72e-04	8	167	2	EFO_0021503
Disease	carbonic anhydrase-related protein 10 measurement	CELSR2 C7	8.72e-04	8	167	2	EFO_0020233
Disease	obsolete aging	STXBP5L RPS6KA2 CNTN5 SNTG1 DIP2C POC5 UBASH3B	1.10e-03	279	167	7	GO_0007568
Disease	repulsive guidance molecule A measurement	RGMA CELSR2	1.12e-03	9	167	2	EFO_0008273
Disease	centronuclear myopathy X-linked (implicated_via_orthology)	MTMR7 MTM1	1.12e-03	9	167	2	DOID:0111225 (implicated_via_orthology)
Disease	alcohol dependence (implicated_via_orthology)	XRCC5 IGF1R	1.12e-03	9	167	2	DOID:0050741 (implicated_via_orthology)
Disease	Drug toxicity	TCN2 AFM SLCO2A1 MTR	1.34e-03	84	167	4	C0013221
Disease	Adverse reaction to drug	TCN2 AFM SLCO2A1 MTR	1.34e-03	84	167	4	C0041755
Disease	cystic kidney disease (implicated_via_orthology)	IFT172 LAMA5	1.39e-03	10	167	2	DOID:2975 (implicated_via_orthology)
Disease	Cleft upper lip	TCN2 MTR NOS3	1.40e-03	39	167	3	C0008924
Disease	Leukoencephalopathy	TCN2 MTR	1.69e-03	11	167	2	C0270612
Disease	triglycerides in large LDL measurement	CELSR2 SYNE2 PCCB	1.86e-03	43	167	3	EFO_0022319
Disease	Paroxysmal atrial fibrillation	IGF1R KCNH2 SYNE2 MYO18B NOS3	1.99e-03	156	167	5	C0235480
Disease	familial atrial fibrillation	IGF1R KCNH2 SYNE2 MYO18B NOS3	1.99e-03	156	167	5	C3468561
Disease	Persistent atrial fibrillation	IGF1R KCNH2 SYNE2 MYO18B NOS3	1.99e-03	156	167	5	C2585653
Disease	Oligospermia	CDC14A NOS3	2.02e-03	12	167	2	C0028960
Disease	decanoylcarnitine measurement	DHX8 SLC44A5	2.02e-03	12	167	2	EFO_0021039
Disease	total lipids in very small VLDL measurement	CELSR2 PCCB ABCG5	2.12e-03	45	167	3	EFO_0022156
Disease	diabetic retinopathy (biomarker_via_orthology)	IGF1R CD59 NOS3	2.12e-03	45	167	3	DOID:8947 (biomarker_via_orthology)
Disease	Atrial Fibrillation	IGF1R KCNH2 SYNE2 MYO18B NOS3	2.22e-03	160	167	5	C0004238
Disease	cardiomyopathy (biomarker_via_orthology)	IGF1R NOS3	2.38e-03	13	167	2	DOID:0050700 (biomarker_via_orthology)
Disease	Respiratory Depression	IGF1R TBCD	2.38e-03	13	167	2	C0235063
Disease	Respiratory Insufficiency	IGF1R TBCD	2.38e-03	13	167	2	C0035229
Disease	complement component C6 measurement	EMB C7	2.38e-03	13	167	2	EFO_0020281
Disease	Respiratory Failure	IGF1R TBCD	2.38e-03	13	167	2	C1145670
Disease	Male sterility	CDC14A MTR NOS3	2.55e-03	48	167	3	C0917731
Disease	Male infertility	CDC14A MTR NOS3	2.55e-03	48	167	3	C0021364
Disease	Subfertility, Male	CDC14A MTR NOS3	2.55e-03	48	167	3	C0848676
Disease	ocular hypertension, response to triamcinolone acetonide	RIOK3 ZNRF4 ITGB4	2.71e-03	49	167	3	EFO_0006954, EFO_1001069
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	TCN2 MTR	2.77e-03	14	167	2	C1858991
Disease	Fanconi anemia	PALB2 FANCB	2.77e-03	14	167	2	cv:C0015625
Disease	Kartagener syndrome (implicated_via_orthology)	DNAAF3 DNAI2	2.77e-03	14	167	2	DOID:0050144 (implicated_via_orthology)
Disease	polycystic kidney disease (implicated_via_orthology)	HDAC6 IFT172	2.77e-03	14	167	2	DOID:0080322 (implicated_via_orthology)
Disease	Prostatic Neoplasms	COL15A1 HDAC6 TCN2 PRDX2 PALB2 SP5 PATJ NOS3 ABCG5 PML	2.78e-03	616	167	10	C0033578
Disease	Malignant neoplasm of prostate	COL15A1 HDAC6 TCN2 PRDX2 PALB2 SP5 PATJ NOS3 ABCG5 PML	2.78e-03	616	167	10	C0376358
Disease	phospholipids in very small VLDL measurement	CELSR2 PCCB ABCG5	3.04e-03	51	167	3	EFO_0022300
Disease	coronary artery disease	SEMA3C ASIC2 EMB RNF213 DNAAF3 OSM CELSR2 DLEC1 UBASH3B ARHGAP20 PCCB ALK NOS3 TBCD ATG16L2	3.33e-03	1194	167	15	EFO_0001645
Disease	Mental Depression	HDAC6 OAS2 MTR RORA ALK NOS3	3.34e-03	254	167	6	C0011570
Disease	pathological myopia	DENND1A CNTN5 ROS1 PML	3.71e-03	111	167	4	EFO_0004207
Disease	pancreatic cancer (is_implicated_in)	ITGA11 PALB2 IGF1R MTR	3.83e-03	112	167	4	DOID:1793 (is_implicated_in)
Disease	pneumonia, COVID-19	ASIC2 DNAAF3 UGDH VPS13B	3.95e-03	113	167	4	EFO_0003106, MONDO_0100096
Disease	triglycerides in LDL measurement	CELSR2 SYNE2 PCCB	3.96e-03	56	167	3	EFO_0022320
Disease	chronotype measurement	ASIC2 PER1 DUS3L DENND1A HNRNPD GPR61 KCNH2 CNTN5 DIP2C CD59 PATJ QARS1	4.55e-03	882	167	12	EFO_0008328
Disease	ankle injury	UGDH DIP2C DLEC1	4.59e-03	59	167	3	EFO_1002021
Disease	brain infarction	SNX33 ALK	4.59e-03	18	167	2	EFO_0004277
Disease	Bone marrow hypocellularity	PALB2 FANCB	4.59e-03	18	167	2	C1855710
Disease	metabolite measurement	SEMA3C LIPF SRR ZNF251 CAPN11 ZNF394 SLC44A5 KCNH2 SYNE2	4.77e-03	560	167	9	EFO_0004725
Disease	Congenital Myasthenic Syndromes, Presynaptic	MYO9A AGRN	5.11e-03	19	167	2	C0751884
Disease	response to supplemental oxygen	ASIC2 CRYBA2	5.11e-03	19	167	2	EFO_0009796
Disease	facial morphology measurement	LRP12 ITGA11 ZNF585A ASIC2 RORA MYO18B ZFP2 VPS13B	5.22e-03	466	167	8	EFO_0007841

Protein segments in the cluster

Peptide	Gene	Start	Entry
FDRARKRIGFAVSAC	BACE1	406	P56817
CFGSSKQRAFDFLNR	AADACL2	116	Q6P093
VFVDRATNQSKCFGF	CELF3	411	Q5SZQ8
SRLFECSNKTGQFVV	AVIL	616	O75366
IRQVFRADGFKCGSD	ATG16L2	536	Q8NAA4
KCDTGLRNSFFSNII	ACTRT3	281	Q9BYD9
QTRCIKNEDGNATRF	ADGRG4	2411	Q8IZF6
TNFAFRRPCFESLKA	AFM	501	P43652
CFDQRKRANAAFLIG	CDC14A	86	Q9UNH5
FKERSGVVCQTGRAF	CDCP1	591	Q9H5V8
CGFKLFTREAASRTF	ALG5	236	Q9Y673
ACTRKQFNKRLSEFG	ACAD9	326	Q9H845
RACARQENVFKKFDG	AGRN	301	O00468
LQAGRKEEAARFCST	CFAP46	186	Q8IYW2
SRVTLFEGDNFQGCK	CRYBA2	106	P53672
RYRCITQQFFRKADG	CRACR2A	606	Q9BSW2
AARASCAAQRQGFEK	CELSR2	2541	Q9HCU4
SLIQESAAKCFFGDR	DUS3L	126	Q96G46
FGNQSFEELRAACLR	CAPN11	61	Q9UMQ6
KFEHCNFNDVTTRLR	CD59	66	P13987
RSEFGKQCNFSDRQA	DNAI2	11	Q9GZS0
LCNLNGFRFSRLTTN	ASIC2	91	Q16515
IYECRAENSRGKNSF	CNTN5	366	O94779
FQAGEDGRILKRFCQ	ITPKC	421	Q96DU7
VLNFFSDCRIRNGEN	GRSF1	166	Q12849
SVDTGFCNFTQRIEK	KIAA1549	1056	Q9HCM3
RIQSAAGRQKAFSTC	OR8I2	226	Q8N0Y5
ITARITGRCDFASKN	POC5	486	Q8NA72
LRSRGCVSAKDFQQL	OGFOD2	46	Q6N063
LRRKFVCFVQNSIGN	IL18RAP	331	O95256
RQIRGELSKQFVCFF	GPR61	346	Q9BZJ8
DKANGYCFRAQEQRS	GPN2	256	Q9H9Y4
SFQDFDIQGSRRCNL	LRP12	91	Q9Y561
YRDNIAGKSFQNRLC	GNPTAB	56	Q3T906
AGLFFCVRNSLSLRN	MUC21	496	Q5SSG8
FGNFLCNSQKERREL	MTMR7	436	Q9Y216
CTLRNNNSSRFGKFI	MYO19	186	Q96H55
SCVAENLAGRAERKF	HMCN2	2336	Q8NDA2
SIRICDFGFAKQLRA	RPS6KA3	556	P51812
RSQAITNCFLERFAK	LPAR4	276	Q99677
SRKFIIANARVENCA	KCNH2	26	Q12809
VVGRSRKASFDQDFC	C2CD4B	306	A6NLJ0
EKLGCSASNFVFART	IGF1R	811	P08069
IICGFDSKNFNTSRL	LIPF	261	P07098
SGLRDFTQEKSVFCR	PER1	286	O15534
GCNLDTARFRFLIGQ	LDHAL6B	211	Q9BYZ2
SKTVRITFGFNCRNK	MORC3	296	Q14149
TFRCVTDRLAIQFGN	BGN	351	P21810
SLSEKNRCDQFRGSV	GAREM1	471	Q9H706
SRKGDAASQFLVFCQ	NSD2	451	O96028
KSFDFSNVLRVICNG	GUCA1C	171	O95843
FQFCPTKAEARRSAA	LIX1L	151	Q8IVB5
FGVALENNRRSAACK	LCA5L	16	O95447
CLNNRFASFINKVRF	KRT82	126	Q9NSB4
FRFSKTVAPALQRCQ	ITGA11	146	Q9UKX5
QFFASSKRDCLERFG	LAMA5	186	O15230
NIIRTFLKENCFRQS	OAS2	371	P29728
KEVRSARCSFNGDFV	ITGB4	461	P16144
KCFVTQLAGFLANRQ	NBPF1	41	Q3BBV0
IAFSNRAEDFRKLGC	PRDX2	56	P32119
GRFNERFILSLASCK	NAT10	181	Q9H0A0
FARKGSCFLINTADR	RBBP5	206	Q15291
RCFSALGQVAKARFL	IFT172	646	Q9UG01
GKLQVFDARDCRSAQ	NOS3	191	P29474
TGLKVCFSSFRELRQ	FANCB	396	Q8NB91
SVKGARFVRFCDAFN	PCCB	371	P05166
QKRTFISQERDCVFG	PALB2	151	Q86YC2
INAKANEGRFCRSSS	BAG2	6	O95816
FARFCKSQESALGNT	DNAAF3	451	Q8N9W5
FVAALDKACGRFINN	CUL1	391	Q13616
FRNRVINTKSFGGQC	C7	151	P10643
QNVAAFERRAATKFG	COQ10A	216	Q96MF6
DFCFLRIRTKGGNSA	FAT3	101	Q8TDW7
CDAFLNVFQSKGLRQ	DIP2C	631	Q9Y2E4
NGRALRREQFQDCFS	ABCG5	116	Q9H222
CRKQLSGQRFTARDD	FHL2	191	Q14192
INQSFTGAERKAALC	IQUB	421	Q8NA54
TDIDSKQRFGFCRLS	DENND1A	76	Q8TEH3
GRNFCRSAKDAFNLL	SLC44A5	581	Q8NCS7
SCFFREEKEQRGTFN	EMB	141	Q6PCB8
KGNFRLVRHVSFVDC	EIF2S3B	121	Q2VIR3
QEGLLDRCVSFQARF	HDAC6	121	Q9UBN7
RGCAFVNARTDFQKD	GTF2IRD2	61	Q86UP8
RGCAFVNARTDFQKD	GTF2IRD2B	61	Q6EKJ0
IRADFQCFKQARAAG	COL15A1	1231	P39059
TRFICKNVGFSVGRF	DLEC1	496	Q9Y238
RFCAKVFGSDSALQI	SALL2	376	Q9Y467
VVGRSRKASFDQDFC	C2CD4A	311	Q8NCU7
FNDLNRFRQSSCGVK	C2CD5	131	Q86YS7
AKTSQFIAFRRQDCD	HELB	736	Q8NG08
VRVQKAICSGFFRNA	DHX8	1101	Q14562
AFCKRNFGDLVSIQS	MRC1	826	P22897
DNKTNKRRGFCFITF	HNRNPD	216	Q14103
GIFRQSANVKSCREL	ARHGAP20	396	Q9P2F6
AKANNGICFLRFDDT	QARS1	291	P47897
VNSRKCLNRFVDEGS	UTP18	411	Q9Y5J1
VKSEACQRFFRDGLT	USP9X	111	Q93008
CQRFFRDGLTISFTK	USP9X	116	Q93008
CGRVRDFVAKLANNT	SORT1	86	Q99523
LFCGKSFTRSDELQR	SP5	331	Q6BEB4
CADTFRAGAFDQLKQ	SRP54	136	P61011
LTQCRGFNLKAYRNA	SEMA3C	561	Q99985
NCRFINSTFLEQKEG	SV2B	511	Q7L1I2
NGDVCKRNVLGTTRF	TMEM131L	551	A2VDJ0
RDKGSNTFQCRINIE	SYNE2	81	Q8WXH0
SIGFLRFCKQATLQF	TMEM184B	166	Q9Y519
RKLDQVSQFGCRSFA	OGA	156	O60502
LDRRKQCFTVQSESG	SNTG1	351	Q9NSN8
EFLDGTRKTNNIFCS	PML	176	P29590
FVNIGERCNVAGSRK	MTR	371	Q99707
RNLNRFSCFVRSGVE	SNX33	181	Q8WV41
IIDATKCGNFARFIN	SETD1B	1891	Q9UPS6
DRAGNVIFRKSARNF	OXCT1	216	P55809
QLTGRNLFFKCELFQ	SRR	36	Q9GZT4
CLAGFRQSERGFREK	OVCA2	11	Q8WZ82
LRTFTDRFQTCKVQG	RGMA	171	Q96B86
ASDAFQRKLEGCRFL	OSM	181	P13725
GNRTLSRDQFDICAK	SLC12A4	311	Q9UP95
ACFAIQKGLQASRSD	SPTLC1	191	O15269
LRTANRLFGEKTCDF	SERPINB8	86	P50452
RIARTFCFTNEGQAL	STXBP5L	1026	Q9Y2K9
LAFTCLKRSNFNPGR	TCN2	201	P20062
NRSLSAVDFFALKNC	ALK	411	Q9UM73
SDAFFTCRKNVLLAN	ANGEL1	21	Q9UNK9
RHKETFQVRECFGNT	USP53	981	Q70EK8
RDCRNVSQFFQKGGV	RIOK3	441	O14730
RNFTRTCQDITGEFK	TMEM156	81	Q8N614
ITRLCVFFGRQKAND	PIK3R4	561	Q99570
GRCARSVFGNIKVFV	SLCO2A1	21	Q92959
TFRQCARFQQGKDLQ	RNF213	2821	Q63HN8
VESCRGKNLFFSTNI	UGDH	61	O60701
EECGKVFNQFSTLTR	ZNF107	331	Q9UII5
KECGRSFRNSSSFNV	ZNF562	291	Q6V9R5
GNCGKSFKQRSDLFR	ZNF394	361	Q53GI3
GECGKAFRVRQQLTF	ZFP30	161	Q9Y2G7
NCFFVLGRNLNIRSE	XIAP	226	P98170
GTFLFNCESARERQK	MTM1	476	Q13496
LRTANRLFGEKTCQF	SERPINB9	86	P50453
AAASRNFLAVKNVRG	PAPLN	216	O95428
EGCKGFFRRSQQSNA	RORA	91	P35398
CSANFDFSRKGLLVF	PATJ	71	Q8NI35
SVCGRAFSRKAQLIQ	ZNF577	161	Q9BSK1
EGCGKRFSLDFNLRT	YY2	316	O15391
CTFDLKVLNAQRAGF	ZNRF4	166	Q8WWF5
RRDTQLAFGCGVSNK	TMEM104	446	Q8NE00
TECGRAFIRKSNFIT	ZNF585B	581	Q52M93
EVRINRQKHRCFSFG	VWA5A	406	O00534
RCFIAFQVRAFTSKG	ROS1	1121	P08922
ITALCTFFIARGNKA	SMCO1	136	Q147U7
TECGRAFIRKSNFIT	ZNF585A	581	Q6P3V2
VLFQAACKGFLSRQE	MYO18B	1341	Q8IUG5
DTCGKNFRRRSALNN	ZNF234	291	Q14588
NECGKAFRARSSLAI	ZNF347	376	Q96SE7
SFQRKFVNEVRRCES	ATP6V0A4	46	Q9HBG4
ERCGKRFVQSSQLAN	ZBTB17	561	Q13105
NECGKAFRRSSTLVQ	ZNF251	436	Q9BRH9
DTCGKNFRQRSALNS	ZNF221	341	Q9UK13
NFRENGFCTRAIVLT	VPS13B	3221	Q7Z7G8
EECGKAFNRSSRLTQ	ZNF429	596	Q86V71
CRRAASAAFQENVGR	TBCD	506	Q9BTW9
HFRSNVGRALFVKTC	ZNF154	66	Q13106
QCFDAKGRYIRTNLN	UBASH3B	406	Q8TF42
NECGKAFSRSTNLTR	ZFP2	441	Q6ZN57
AGNLTAAREKFSRCL	ZFYVE26	2076	Q68DK2
SLRAAVAFKAEGQRC	TTC9B	61	Q8N6N2
NQKVRLSVSGFLCAF	USP32	981	Q8NFA0
AFKQTVCGFDLLRAN	PPIP5K1	311	Q6PFW1
GIRCEKQNNAFSTLF	TRPC4	551	Q9UBN4
SVLGFCKSSQVQRRF	XRCC5	341	P13010
NECGKSFFQVSSLLR	ZNF81	361	P51508
SSFVRNPAECNVRGK	ZNF487	186	B1APH4
EQRSVFSQCGKAFSL	ZNF266	126	Q14584
RVCDFGFAKQLRAGN	RPS6KA2	551	Q15349
QSTCRGFRARQRFKA	MYO9A	1146	B2RTY4
AACRNFAKDQASRKS	NDEL1	271	Q9GZM8