Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A HCN3

9.45e-0426352GO:0005248
GeneOntologyMolecularFunctionmetalloendopeptidase activity

MMP2 MMP14 ADAMTS7

1.20e-03120353GO:0004222
GeneOntologyBiologicalProcessproteoglycan metabolic process

HGSNAT ADAMTS7 CANT1 UST

2.15e-0597354GO:0006029
GeneOntologyBiologicalProcessresponse to mechanical stimulus

SCN11A MMP2 ATR MMP14 PKD1L1

5.72e-05247355GO:0009612
GeneOntologyBiologicalProcessmyeloid leukocyte migration

MMP2 DYSF MMP14 PTPRO PIK3CG

9.67e-05276355GO:0097529
HumanPhenoSclerotic cranial sutures

MMP2 MMP14

1.46e-052202HP:0005441
HumanPhenoOsteolysis involving tarsal bones

MMP2 MMP14

4.38e-053202HP:0006234
HumanPhenoCarpal osteolysis

MMP2 MMP14

4.38e-053202HP:0001495
DomainCYSTEINE_SWITCH

MMP2 MMP14 ADAMTS7

6.67e-0541363PS00546
DomainPept_M10_metallopeptidase

MMP2 MMP14 ADAMTS7

7.70e-0543363IPR001818
DomainDUF1220

NBPF4 NBPF6

1.29e-049362SM01148
DomainNBPF

NBPF4 NBPF6

1.97e-0411362PS51316
DomainDUF1220

NBPF4 NBPF6

1.97e-0411362PF06758
DomainNBPF_dom

NBPF4 NBPF6

1.97e-0411362IPR010630
DomainPept_M10A_Zn_BS

MMP2 MMP14

3.73e-0415362IPR021158
DomainPI3/4_kinase_CS

ATR PIK3CG

3.73e-0415362IPR018936
DomainPI3Kc

ATR PIK3CG

4.26e-0416362SM00146
Domain-

ATR PIK3CG

4.26e-04163621.10.1070.11
DomainARM-type_fold

UTP20 MYBBP1A ATR RALGAPA2 PIK3CG

4.54e-04339365IPR016024
DomainHemopexin_CS

MMP2 MMP14

4.82e-0417362IPR018486
DomainMetalloPept_cat_dom

MMP2 MMP14 ADAMTS7

5.06e-0481363IPR024079
Domain-

MMP2 MMP14 ADAMTS7

5.06e-04813633.40.390.10
DomainPI3_4_KINASE_1

ATR PIK3CG

5.42e-0418362PS00915
DomainPI3_4_KINASE_2

ATR PIK3CG

5.42e-0418362PS00916
DomainPI3/4_kinase_cat_dom

ATR PIK3CG

5.42e-0418362IPR000403
DomainPI3_PI4_kinase

ATR PIK3CG

5.42e-0418362PF00454
DomainPI3_4_KINASE_3

ATR PIK3CG

5.42e-0418362PS50290
DomainPG_binding_1

MMP2 MMP14

6.72e-0420362PF01471
DomainPeptidoglycan-bd-like

MMP2 MMP14

6.72e-0420362IPR002477
DomainZINC_PROTEASE

MMP2 MMP14 ADAMTS7

8.82e-0498363PS00142
DomainHemopexin-like_dom

MMP2 MMP14

8.91e-0423362IPR000585
DomainHemopexin

MMP2 MMP14

8.91e-0423362PF00045
DomainHEMOPEXIN

MMP2 MMP14

8.91e-0423362PS00024
Domain-

MMP2 MMP14

8.91e-04233622.110.10.10
DomainHEMOPEXIN_2

MMP2 MMP14

8.91e-0423362PS51642
DomainHemopexin-like_repeat

MMP2 MMP14

8.91e-0423362IPR018487
DomainHX

MMP2 MMP14

8.91e-0423362SM00120
DomainPept_M10A

MMP2 MMP14

8.91e-0423362IPR021190
DomainM10A_MMP

MMP2 MMP14

8.91e-0423362IPR033739
DomainPeptidase_M10

MMP2 MMP14

9.71e-0424362PF00413
DomainIon_trans_dom

SCN11A KCNA7 HCN3

1.37e-03114363IPR005821
DomainIon_trans

SCN11A KCNA7 HCN3

1.37e-03114363PF00520
DomainZnMc

MMP2 MMP14

1.42e-0329362SM00235
DomainPeptidase_Metallo

MMP2 MMP14

1.42e-0329362IPR006026
Domain-

DYSF PIK3CG SYNGAP1

2.87e-031483632.60.40.150
DomainC2_dom

DYSF PIK3CG SYNGAP1

3.84e-03164363IPR000008
DomainHEAT

UTP20 ATR

3.85e-0348362PF02985
DomainChannel_four-helix_dom

SCN11A KCNA7

5.39e-0357362IPR027359
Domain-

SCN11A KCNA7

5.39e-03573621.20.120.350
DomainHEAT

UTP20 ATR

5.58e-0358362IPR000357
PathwayBIOCARTA_RECK_PATHWAY

MMP2 MMP14

1.67e-049312MM1579
PathwayBIOCARTA_RECK_PATHWAY

MMP2 MMP14

1.67e-049312M22068
Pubmed

The hemopexin domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) Is not required for its activation of proMMP2 on cell surface but is essential for MT1-MMP-mediated invasion in three-dimensional type I collagen.

MMP2 MMP14

1.10e-06237215381707
Pubmed

Limited independent prognostic value of MMP-14 and MMP-2 expression in ovarian cancer.

MMP2 MMP14

1.10e-06237227038607
Pubmed

Expression of membrane-type-1-matrix metalloproteinase and metalloproteinase-2 in nonsmall cell lung carcinomas.

MMP2 MMP14

1.10e-06237211844598
Pubmed

Novel Roles of MT1-MMP and MMP-2: Beyond the Extracellular Milieu.

MMP2 MMP14

1.10e-06237236076910
Pubmed

Membrane type-1 matrix metalloprotease-independent activation of pro-matrix metalloprotease-2 by proprotein convertases.

MMP2 MMP14

1.10e-06237219780834
Pubmed

Angiostatin inhibits endothelial MMP-2 and MMP-14 expression: a hypoxia specific mechanism of action.

MMP2 MMP14

1.10e-06237223220260
Pubmed

Immunohistochemical expression of MMP-14 and MMP-2, and MMP-2 activity during human ovarian follicular development.

MMP2 MMP14

1.10e-06237224485069
Pubmed

Regulation of vascular smooth muscle cell expression and function of matrix metalloproteinases is mediated by estrogen and progesterone exposure.

MMP2 MMP14

1.10e-06237218829229
Pubmed

Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin.

MMP2 MMP14

1.10e-06237212473650
Pubmed

An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature.

MMP2 MMP14

1.10e-06237215805464
Pubmed

MMP-14 and MMP-2 are key metalloproteases in Dupuytren's disease fibroblast-mediated contraction.

MMP2 MMP14

1.10e-06237222342364
Pubmed

Role of metalloproteinases at the onset of liver development.

MMP2 MMP14

1.10e-06237218445063
Pubmed

Vein tissue expression of matrix metalloproteinase as biomarker for hemodialysis arteriovenous fistula maturation.

MMP2 MMP14

1.10e-06237220724289
Pubmed

Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.

MMP2 MMP14

1.10e-06237217483344
Pubmed

Neurokinin-1 receptor mediated breast cancer cell migration by increased expression of MMP-2 and MMP-14.

MMP2 MMP14

1.10e-06237227498853
Pubmed

Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells.

MMP2 MMP14

1.10e-06237218627313
Pubmed

Membrane-type 1 matrix metalloproteinase is required for normal alveolar development.

MMP2 MMP14

1.10e-06237215739229
Pubmed

Plasmin activates pro-matrix metalloproteinase-2 with a membrane-type 1 matrix metalloproteinase-dependent mechanism.

MMP2 MMP14

1.10e-06237212115722
Pubmed

Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts.

MMP2 MMP14

1.10e-06237219523958
Pubmed

Degenerate wave and capacitive coupling increase human MSC invasion and proliferation while reducing cytotoxicity in an in vitro wound healing model.

MMP2 MMP14

1.10e-06237221858102
Pubmed

MT1-MMP regulates MMP-2 expression and angiogenesis-related functions in human umbilical vein endothelial cells.

MMP2 MMP14

1.10e-06237223796708
Pubmed

Protein expression of MMP-2 and MT1-MMP in actinic keratosis, squamous cell carcinoma of the skin, and basal cell carcinoma.

MMP2 MMP14

1.10e-06237224984957
Pubmed

Androgens regulate MMPs and the cellular processes of intimal hyperplasia.

MMP2 MMP14

1.10e-06237223773714
Pubmed

A matrix metalloproteinase expressed on the surface of invasive tumour cells.

MMP2 MMP14

1.10e-0623728015608
Pubmed

Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells.

MMP2 MMP14

1.10e-06237219286653
Pubmed

Calcium regulation of matrix metalloproteinase-mediated migration in oral squamous cell carcinoma cells.

MMP2 MMP14

1.10e-06237212194986
Pubmed

Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival.

MMP2 MMP14

1.10e-06237231282404
Pubmed

Evidence for the Involvement of MMP14 in MMP2 Processing and Recruitment in Exosomes of Corneal Fibroblasts.

MMP2 MMP14

1.10e-06237225015352
Pubmed

E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters.

MMP2 MMP14

3.30e-06337215756447
Pubmed

Expression of gelatinases (MMP-2, MMP-9) and gelatinase activator (MMP-14) in actinic keratosis and in in situ and invasive squamous cell carcinoma.

MMP2 MMP14

3.30e-06337222534634
Pubmed

AG-9, an Elastin-Derived Peptide, Increases In Vitro Oral Tongue Carcinoma Cell Invasion, through an Increase in MMP-2 Secretion and MT1-MMP Expression, in a RPSA-Dependent Manner.

MMP2 MMP14

3.30e-06337233396696
Pubmed

Platelet activating factor inhibits the expression of matrix metalloproteinases and affects invasiveness and differentiation in a system of human neuroblastoma clones.

MMP2 MMP14

3.30e-06337211928813
Pubmed

Direct activation of pro-matrix metalloproteinase-2 by leukolysin/membrane-type 6 matrix metalloproteinase/matrix metalloproteinase 25 at the asn(109)-Tyr bond.

MMP2 MMP14

3.30e-06337214583471
Pubmed

NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II.

NOX4 MMP2

3.30e-06337221965295
Pubmed

MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling.

MMP2 MMP14

3.30e-06337220152179
Pubmed

Neurokinin-1 receptor directly mediates glioma cell migration by up-regulation of matrix metalloproteinase-2 (MMP-2) and membrane type 1-matrix metalloproteinase (MT1-MMP).

MMP2 MMP14

3.30e-06337223166329
Pubmed

MT-MMP, the cell surface activator of proMMP-2 (pro-gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis.

MMP2 MMP14

3.30e-0633728743942
Pubmed

Matrix metalloproteinase gene polymorphisms and bronchopulmonary dysplasia: identification of MMP16 as a new player in lung development.

MMP2 MMP14

3.30e-06337218784838
Pubmed

Expression and role of metalloproteinase-2 and endogenous tissue regulator in ameloblastoma.

MMP2 MMP14

3.30e-06337219709349
Pubmed

Association of metalloproteinase gene polymorphisms with systemic sclerosis in the European Caucasian population.

MMP2 MMP14

3.30e-06337220110530
Pubmed

Cloning of murine membrane-type-1-matrix metalloproteinase (MT-1-MMP) and its metanephric developmental regulation with respect to MMP-2 and its inhibitor.

MMP2 MMP14

3.30e-0633729648071
Pubmed

The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury.

MYBBP1A NAT10

3.30e-06337238583415
Pubmed

Activation ratio of MMP-2 and expression of MT1-MMP are correlated in thymic epithelial tumours.

MMP2 MMP14

3.30e-06337217886098
Pubmed

[The role of matrix metalloproteinases and their tissue inhibitors in oral lichen planus].

MMP2 MMP14

3.30e-06337217067460
Pubmed

Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion.

MMP2 MMP14

3.30e-06337211920503
Pubmed

The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.

MMP2 MMP14

3.30e-06337216776850
Pubmed

Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway.

MMP2 MMP14

3.30e-06337217283058
Pubmed

The planar cell polarity protein Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase-dependent invasion.

MMP2 MMP14

3.30e-06337219577357
Pubmed

Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression.

MMP2 MMP14

3.30e-06337219051246
Pubmed

E6/E7 oncoproteins of high risk HPV-16 upregulate MT1-MMP, MMP-2 and MMP-9 and promote the migration of cervical cancer cells.

MMP2 MMP14

3.30e-06337226191191
Pubmed

Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium.

MMP2 MMP14

3.30e-06337212372458
Pubmed

Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.

MMP2 MMP14

3.30e-06337220586027
Pubmed

Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14.

MMP2 MMP14

3.30e-06337227613828
Pubmed

Distinct progression-associated expression of tumor and stromal MMPs in HaCaT skin SCCs correlates with onset of invasion.

MMP2 MMP14

3.30e-06337219610062
Pubmed

Temporal expression and activation of matrix metalloproteinases-2, -9, and membrane type 1-matrix metalloproteinase following acute hindlimb ischemia.

MMP2 MMP14

3.30e-06337212842442
Pubmed

Norcantharidin enhances TIMP‑2 anti‑vasculogenic mimicry activity for human gallbladder cancers through downregulating MMP‑2 and MT1‑MMP.

MMP2 MMP14

3.30e-06337225405519
Pubmed

Involvement of matrix metalloproteinases in the adipose conversion of 3T3-L1 preadipocytes.

MMP2 MMP14

3.30e-06337212049638
Pubmed

Collagen I and thrombin activate MMP-2 by MMP-14-dependent and -independent pathways: implications for airway smooth muscle migration.

MMP2 MMP14

3.30e-06337217189319
Pubmed

Membrane-type-1 matrix metalloproteinase, matrix metalloproteinase 2, and tissue inhibitor of matrix proteinase 2 in prostate cancer: identification of patients with poor prognosis by immunohistochemistry.

MMP2 MMP14

3.30e-06337218329693
Pubmed

MT1-MMP modulates melanoma cell dissemination and metastasis through activation of MMP2 and RAC1.

MMP2 MMP14

3.30e-06337224387669
Pubmed

TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation.

MMP2 MMP14

3.30e-06337220056917
Pubmed

The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.

MMP2 MMP14

3.30e-06337219330734
Pubmed

Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts.

MMP2 MMP14

3.30e-06337217099140
Pubmed

Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue.

MMP2 MMP14

3.30e-06337222527932
Pubmed

Mechanical forces-induced human osteoblasts differentiation involves MMP-2/MMP-13/MT1-MMP proteolytic cascade.

MMP2 MMP14

3.30e-06337222006368
Pubmed

Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix.

MMP2 MMP14

3.30e-06337212393408
Pubmed

Quantitative expression of MMPs 2, 9, 14, and collagen IV in LCIS and paired normal breast tissue.

MMP2 MMP14

3.30e-06337231530842
Pubmed

MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.

MMP2 MMP14

3.30e-06337215522913
Pubmed

Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells.

MMP2 MMP14

3.30e-06337211839588
Pubmed

Expression and prognostic role of MMP2, MMP9, MMP13, and MMP14 matrix metalloproteinases in sinonasal and oral malignant melanomas.

MMP2 MMP14

3.30e-06337218045645
Pubmed

Effect on the expression of MMP-2, MT-MMP in laryngeal carcinoma Hep-2 cell line by antisense glucose transporter-1.

MMP2 MMP14

3.30e-06337222835601
Pubmed

A pericellular collagenase directs the 3-dimensional development of white adipose tissue.

MMP2 MMP14

6.60e-06437216678100
Pubmed

Functional roles of MMP14 and MMP15 in early postnatal mammary gland development.

MMP2 MMP14

6.60e-06437227633994
Pubmed

Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.

MMP2 MMP14

6.60e-06437217709990
Pubmed

Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.

MMP2 MMP14

6.60e-06437222327326
Pubmed

The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.

MMP2 MMP14

6.60e-0643728663332
Pubmed

EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.

MMP2 MMP14

6.60e-06437216425263
Pubmed

The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.

MMP2 MMP14

6.60e-06437217175151
Pubmed

Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co-regulate axonal outgrowth of mouse retinal ganglion cells.

MMP2 MMP14

6.60e-06437224611815
Pubmed

Membrane-type 1 matrix metalloproteinase regulates macrophage-dependent elastolytic activity and aneurysm formation in vivo.

MMP2 MMP14

6.60e-06437219010778
Pubmed

3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases.

MMP2 MMP14

6.60e-06437216551362
Pubmed

Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.

MMP2 MMP14

6.60e-06437227458061
Pubmed

Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice.

MMP2 MMP14

6.60e-06437215064723
Pubmed

Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma.

MMP2 MMP14

6.60e-06437215743799
Pubmed

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.

MMP2 MMP14

6.60e-06437217623673
Pubmed

Prion fragment peptides are digested with membrane type matrix metalloproteinases and acquire enzyme resistance through Cu²⁺-binding.

MMP2 MMP14

6.60e-06437224970228
Pubmed

TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent.

MMP2 MMP14

6.60e-06437218762577
Pubmed

Downregulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and downregulates MMPs expression.

MMP2 MMP14

6.60e-06437221276823
Pubmed

Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis.

MMP2 MMP14

6.60e-06437215911696
Pubmed

Claudin promotes activation of pro-matrix metalloproteinase-2 mediated by membrane-type matrix metalloproteinases.

MMP2 MMP14

6.60e-06437211382769
Pubmed

Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.

MMP2 MMP14

6.60e-06437219820359
Pubmed

Gene expression of adhesion molecules and matrix metalloproteinases in endometriosis.

MMP2 MMP14

1.10e-05537212587534
Pubmed

MT1-MMP-dependent remodeling of cardiac extracellular matrix structure and function following myocardial infarction.

MMP2 MMP14

1.10e-05537222464947
Pubmed

Angiotensin II stimulates cardiac fibroblast migration via the differential regulation of matrixins and RECK.

MMP2 MMP14

1.10e-05537224095877
Pubmed

Diminished matrix metalloproteinase 2 (MMP-2) in ectomesenchyme-derived tissues of the Patch mutant mouse: regulation of MMP-2 by PDGF and effects on mesenchymal cell migration.

MMP2 MMP14

1.10e-05537210433819
Pubmed

MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells.

MMP2 MMP14

1.10e-05537216147977
Pubmed

Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs.

MMP2 MMP14

1.65e-05637230269950
Pubmed

Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.

MMP2 MMP14

1.65e-05637210947989
Pubmed

Matrix metalloproteinase 14 is required for fibrous tissue expansion.

MMP2 MMP14

1.65e-05637226390284
Pubmed

Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation.

MMP2 MMP14

1.65e-05637215572153
CytobandEnsembl 112 genes in cytogenetic band chr1p13

NBPF4 NBPF6 VANGL1

6.63e-04211373chr1p13
CytobandEnsembl 112 genes in cytogenetic band chr15q23

THAP10 MYO9A

1.39e-0368372chr15q23
Cytoband1p13.3

NBPF4 NBPF6

1.43e-03693721p13.3
GeneFamilyNeuroblastoma breakpoint family

NBPF4 NBPF6

3.20e-0423212662
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP2 MMP14

3.49e-0424212891
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P3|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NOX4 MMP2 DPY19L2 ADAMTS7

8.99e-07893749e7041ab9409028007fefe53db6d1048eafae93b
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NOX4 MMP2 DPY19L2 ADAMTS7

8.99e-0789374e7abf4af18d63c9384d25365a827e85a9adee964
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NOX4 MMP2 DPY19L2 ADAMTS7

8.99e-0789374436e1229ee28517c11dfe0a5d1cdad3477419e00
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NOX4 MMP2 DPY19L2 ADAMTS7

8.99e-07893744e5f4c0404968422703c248488e6b2ee8737dc00
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

MMP2 DYSF MMP14 IL4I1

1.29e-051743744c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCellCOVID-19_Mild-Hematopoietic_SC-HSPC|COVID-19_Mild / Disease group, lineage and cell class

DNAAF3 MMP2 DPY19L2 HDC

1.44e-0517937419fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCellCOVID-19_Mild-Hematopoietic_SC|COVID-19_Mild / Disease group, lineage and cell class

DNAAF3 MMP2 DPY19L2 HDC

1.44e-0517937450a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAAF3 MMP2 DPY19L2 HDC

1.51e-0518137454a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAAF3 MMP2 DPY19L2 HDC

1.51e-051813745b84625b1d3737708001b64f6da9360330d39a27
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAAF3 MMP2 DPY19L2 HDC

1.51e-05181374e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DYSF MMP14 IL4I1

1.57e-051833748e9d45c96b44558158e3d59613f64a73d5390c19
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DYSF MMP14 IL4I1

1.57e-051833740408d991ddb639594b45d5cb2432dd29289167b1
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DYSF MMP14 IL4I1

1.57e-0518337479f05b8a967124d831b0baef137e30659f5917a7
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MMP2 DYSF MMP14 IL4I1

1.61e-051843747331535d469453a5264dcb0270a97f63d3b55201
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MMP2 DYSF MMP14 IL4I1

1.61e-0518437492202e1cd0bba1ce4b061ebcb8a2af5bb590542a
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MMP2 DYSF MMP14 IL4I1

1.61e-05184374337e38a6b2b6770cc992d88b006829f194841b10
ToppCellControl-Myeloid-transitional_Macro|Control / Disease group,lineage and cell class (2021.01.30)

MMP2 DYSF MMP14 IL4I1

1.86e-051913743ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

NOX4 MMP2 DYSF MMP14

1.98e-0519437455b97095a7a17a312c616703d291738a0f806339
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NOX4 MMP2 KCNA7

1.38e-041213735035e071033cb76a7fc0128716755b14821e8f05
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NOX4 MMP2 KCNA7

1.38e-04121373c96115bd33455296378a257583b49442d00b39ca
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MMP2 ADAMTS7 PKD1L1

2.08e-04139373a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MMP2 KCNA7 ADAMTS7

2.81e-0415437365dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NOX4 PTPRO UST

2.86e-04155373cba6f3f7742b4d5d54ad0a0ac0dd4016e73fe658
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL4I1 MYO9A UST

2.97e-04157373ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellCOVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

MMP2 DPY19L2 HDC

3.02e-041583730d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCellCV-Healthy-3|CV / Virus stimulation, Condition and Cluster

VANGL1 BAP1 SYNGAP1

3.20e-04161373fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCellIIF-Other-HSPC|IIF / Disease, Lineage and Cell Type

MMP2 DPY19L2 HDC

3.31e-041633731e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCell368C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DNAAF3 IL4I1 VANGL1

3.37e-0416437367c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCell343B-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SCN11A DPY19L2 IL4I1

3.37e-04164373eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 ATR IL4I1

3.37e-0416437378de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCell368C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

DNAAF3 IL4I1 VANGL1

3.43e-041653739d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAAF3 ATR IL4I1

3.43e-04165373c39f0479955c4e23921f7a450d3bc251a002200f
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-mDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL4I1 PTPRO PIK3CG

3.62e-041683732dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FASTKD5 PIK3CG VANGL1

3.62e-041683738459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TTC8 UST NAT10

3.62e-041683738c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

DNAAF3 MMP2 IL4I1

3.62e-04168373d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MMP2 UST VANGL1

3.68e-041693730425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SCN11A DPY19L2 IL4I1

3.68e-04169373e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MMP2 UST VANGL1

3.68e-04169373fec669968a77060bd77ee8695034e35a642c984f
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

DNAAF3 MMP2 IL4I1

3.75e-0417037397df5ffb328196c46568975d2d97722bcc753bf5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 DPY19L2 HDC

3.75e-04170373b535baeb4dbd644051cf992babb61add9eaae4e3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 DPY19L2 HDC

3.75e-041703732477c9f29dbe27f172df699003971e828d6ab8c9
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FASTKD5 MYBBP1A NAT10

3.75e-04170373070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SCN11A PTPRO PIK3CG

3.81e-0417137352fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPY19L2 ZNF44 SYNGAP1

3.81e-041713731854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SCN11A PTPRO PIK3CG

3.81e-04171373e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO MYO9A UST

3.88e-041723737fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO MYO9A UST

3.88e-041723732a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP2 ADAMTS7 HCN3

3.88e-04172373c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

NOX4 DYSF ADAMTS7

3.88e-04172373c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell368C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DPY19L2 ADAMTS7 HDC

3.94e-041733738cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell368C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DPY19L2 ADAMTS7 HDC

3.94e-04173373fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 ATR IL4I1

4.01e-041743737be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 PTPRO HDC

4.01e-04174373773329bb91b97578df138446cf62101dd0dad758
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAAF3 ATR IL4I1

4.08e-041753731b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP2 ADAMTS7 HCN3

4.08e-04175373a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 DPY19L2 HDC

4.22e-04177373ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCellsevere_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

MMP2 DPY19L2 HDC

4.22e-04177373289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

MMP2 DYSF MMP14

4.22e-04177373470f54fe2b21c7350ea471e02039461a3808f700
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MMP2 DYSF IL4I1

4.22e-041773733a94ee9b58ebdbbc75e00954cf1f6922f88f8f88
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 DPY19L2 HDC

4.22e-04177373bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-4_RORB_FOLH1B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NOX4 DYSF MCHR2

4.29e-0417837322955b82917206aeed49dc0ac4630ccd9e51c4a5
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DPY19L2 HDC

4.36e-041793732f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|metastatic_Brain / Location, Cell class and cell subclass

NOX4 MMP2 DYSF

4.36e-0417937356fe381ffbaba3a4f2f587a3e367b0d11fbd4a2a
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DPY19L2 HDC

4.36e-041793734bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IL4I1 PTPRO PIK3CG

4.36e-041793739fc44637c9a7551fd47b8533e45a9c199e164a95
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DPY19L2 HDC

4.36e-041793733e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

NOX4 MMP2 UST

4.36e-04179373dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOX4 MMP2 MMP14

4.43e-04180373935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell5'-Airway_Nasal-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOX4 MMP2 MMP14

4.43e-041803733dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCellsystemic_lupus_erythematosus-treated-Hematopoietic-progenitor_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DNAAF3 SCN11A MMP2

4.43e-041803732694f5deaed551c53e74d8a9fbd41d3734bb9f37
ToppCellsystemic_lupus_erythematosus-treated-Hematopoietic-progenitor_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DNAAF3 SCN11A MMP2

4.43e-04180373ef0de602fc8ccfd32a06978ac0100afe0ce1beeb
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP2 DPY19L2 MMP14

4.50e-041813736730e249cac55ae892cc567d9211615882f3dab4
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DNAAF3 MMP2 HDC

4.50e-04181373070ae3f3fe0e177fabcf34e64a0f158b01354837
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP2 DPY19L2 MMP14

4.50e-041813733462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellControl-Hematopoietic_SC-HSPC|Control / Disease group, lineage and cell class

MMP2 DPY19L2 HDC

4.57e-0418237314e347c0e6444410f1948851407bb18c706569f4
ToppCellControl-Hematopoietic_SC|Control / Disease group, lineage and cell class

MMP2 DPY19L2 HDC

4.57e-0418237343243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DPY19L2 HDC

4.57e-04182373d0ebf2f0d5370458ab81485a0017c311077133d5
ToppCellPBMC-Control-Hematopoietic-HSPC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DPY19L2 HDC

4.57e-04182373918286422b3eab32d962b49aa07b1b9512e51d9d
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP2 DPY19L2 HDC

4.57e-041823732a6d1246bfb5899a0861c7f2f8fb9b43b0df8acc
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOX4 MMP2 MMP14

4.65e-041833736d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP2 MMP14 ADAMTS7

4.65e-041833737e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOX4 MMP2 MMP14

4.65e-04183373cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOX4 MMP2 MMP14

4.65e-04183373803376f5260de83c48d4f7301278d078a32b3e6e
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP2 MMP14 ADAMTS7

4.65e-0418337363294d66e3ccf152ffe5d1237106764c14390b62
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RALGAPA2 DYSF IL4I1

4.72e-04184373c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

MMP2 MMP14 UST

4.72e-04184373684d05340a3dfb8aa08b881516a37f9627a10448
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 HCN3 HDC

4.72e-04184373d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 HCN3 HDC

4.72e-0418437322010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 HCN3 HDC

4.72e-04184373264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellBAL-Control-Myeloid-MoAM-MoAM4|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DYSF MMP14 IL4I1

4.79e-04185373274b8acccdfe434d14af4cb32fb615c06ec98435
ToppCellBAL-Control-Myeloid-MoAM-MoAM4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DYSF MMP14 IL4I1

4.79e-0418537329d7ddcb9a2e45f76cd5611f7c52b6df689effd3
ToppCellBAL-Control-Myeloid-MoAM-MoAM4-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DYSF MMP14 IL4I1

4.79e-04185373b640d9ed6a1e6aa595053065bb992efc0402353e
ToppCellBAL-Control-Myeloid-MoAM-MoAM4-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DYSF MMP14 IL4I1

4.79e-04185373780bdb63ef913a09930063286011c9108381d3a9
ToppCellCOVID-19_Moderate-HSPC|COVID-19_Moderate / disease group, cell group and cell class

MMP2 DPY19L2 HDC

4.79e-04185373cacc6ab5f26f6c803894567fb838ea06eaa7efe5
ToppCellproximal-3-Hematologic-Myeloid_Dendritic_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

UTP20 IL4I1 PIK3CG

4.87e-04186373c920dffd24f051b54d8b48f801fffc928d99e135
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

UTP20 IL4I1 PIK3CG

4.87e-04186373d740aca5dc4240851ba7bc5988c0970d785ad0c2
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_1|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

UTP20 IL4I1 PIK3CG

4.87e-041863734ca7f6c043874a0c536f75af5ca24c7c66725e54
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN11A RALGAPA2 DYSF

4.87e-04186373055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-osteoclast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MMP14 UST XPR1

4.87e-04186373c9dfcf7bba7e5ef97ad5d9b7084fba932c91ab68
ComputationalMMPs.

MMP2 MMP14

6.76e-0421202MODULE_562
ComputationalGenes in the cancer module 371.

MMP2 MMP14

1.04e-0326202MODULE_371
ComputationalGenes in the cancer module 210.

MMP2 MMP14

1.21e-0328202MODULE_210
ComputationalGenes in the cancer module 95.

THAP10 NOX4 ADAMTS7 UST SYNGAP1

3.04e-03560205MODULE_95
ComputationalMetal ion (zinc) binding.

MMP2 MMP14

3.10e-0345202MODULE_280
ComputationalGenes in the cancer module 163.

THAP10 NOX4 ADAMTS7 UST SYNGAP1

3.16e-03565205MODULE_163
DrugIH 764-3

MMP2 MMP14

2.57e-062372ctd:C079053
DiseaseMulticentric osteolysis nodulosis arthropathy spectrum

MMP2 MMP14

1.45e-062362cv:C1850155
DiseaseMarfan syndrome (is_marker_for)

MMP2 MMP14

8.67e-064362DOID:14323 (is_marker_for)
DiseaseBone neoplasms

MMP2 BAP1

4.03e-058362C0005967
DiseaseMalignant Bone Neoplasm

MMP2 BAP1

4.03e-058362C0279530
Diseaseabdominal aortic aneurysm (is_marker_for)

MMP2 MMP14

6.47e-0510362DOID:7693 (is_marker_for)
Diseaseintracranial aneurysm (is_marker_for)

MMP2 MMP14

1.30e-0414362DOID:10941 (is_marker_for)
Diseaseabdominal aortic aneurysm (biomarker_via_orthology)

MMP2 MMP14

1.30e-0414362DOID:7693 (biomarker_via_orthology)
DiseaseNasopharyngeal carcinoma

MMP2 BAP1

3.29e-0422362C2931822
Diseasedilated cardiomyopathy (is_marker_for)

MMP2 MMP14

1.04e-0339362DOID:12930 (is_marker_for)
DiseaseCalcinosis

MMP2 XPR1

1.21e-0342362C0006663
DiseaseMicrocalcification

MMP2 XPR1

1.21e-0342362C0521174
Diseaseage at onset, alcohol dependence

DNAAF3 UTP20

1.21e-0342362EFO_0004847, MONDO_0007079
DiseaseTumoral calcinosis

MMP2 XPR1

1.21e-0342362C0263628

Protein segments in the cluster

PeptideGeneStartEntry
LILLIGTWALFFRKR

VANGL1

161

Q8TAA9
FIFLFKWIEERRSRR

BAP1

46

Q92560
SFLSYELWPRALRKR

ADAMTS7

56

Q9UKP4
KAFRVWESATPLRFR

MMP14

146

P50281
IRGEIFFFKDRFIWR

MMP2

481

P08253
FFFKDRFIWRTVTPR

MMP2

486

P08253
IRRRLPFSKWRLAFR

NBPF4

601

Q96M43
IPLSRRFRSVKLWFV

HDC

351

P19113
RFRSVKLWFVIRSFG

HDC

356

P19113
DPRFRPRWKVILTFF

CANT1

36

Q8WVQ1
LFGWLFRRVRFEKVI

DPY19L2

576

Q6NUT2
PRAIRTRYLRTWFLV

HCN3

161

Q9P1Z3
AWETKVFPTIRRRFR

HECTD4

2256

Q9Y4D8
KILQFLPERIFFRWH

RALGAPA2

91

Q2PPJ7
AFWKDFRRRFLALLS

NAT10

766

Q9H0A0
PERAVFRLRKWIIFR

MYBBP1A

441

Q9BQG0
FRLRKWIIFRLVSIV

MYBBP1A

446

Q9BQG0
NSRLFIGRPRWKLLF

NOX4

516

Q9NPH5
ARRLLPLLWLFVLFK

PTPRO

11

Q16827
RYFALVQPFRLTRWR

MCHR2

131

Q969V1
TLFPRRIFLEWRTAV

ATR

641

Q13535
WRYLGRKVPRFLNIF

FASTKD5

251

Q7L8L6
PRRAFARQLWLLFEF

KCNA7

121

Q96RP8
LRTLSRAKFWPRRRF

DNAAF3

61

Q8N9W5
RAKFWPRRRFNFFVL

DNAAF3

66

Q8N9W5
FRLLGKIAWRSFLLI

HGSNAT

336

Q68CP4
RRFRWAIILFIILFI

DYSF

2041

O75923
ARWLRGILLFLFTLK

PKD1L1

2611

Q8TDX9
PATKVFLSFRRPFWR

IL4I1

351

Q96RQ9
FFLFLIVSVWSPRRL

TAS2R50

241

P59544
RFLLWRALTKFPERV

UTP20

821

O75691
IRRRLPFSKWRLAFR

NBPF6

601

Q5VWK0
LRNKRIGHFLFWFLR

PIK3CG

686

P48736
RFWLLKLLFRVFTAP

XPR1

371

Q9UBH6
WKRRVPLLPFLRFSL

UST

31

Q9Y2C2
EPLLLAWSYFRRRKF

TTC8

6

Q8TAM2
FPRELKEVFASWRLR

SYNGAP1

561

Q96PV0
LQKRSWPFLRSFRVL

SCN11A

661

Q9UI33
WPFLRSFRVLRVFKL

SCN11A

666

Q9UI33
FRFPKDRAVRLLWDR

THAP10

21

Q9P2Z0
RKAFFWPSFLLRHER

ZNF44

586

P15621
PVAVFRWAILRAFFR

MYO9A

696

B2RTY4