Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	5.15e-12	37	92	8	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	6.50e-12	38	92	8	GO:0070001
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-8 ERVK-7	1.52e-05	11	92	3	GO:0004523
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-6 USP34 ADAM21 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	2.89e-05	430	92	10	GO:0004175
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-8 ERVK-7	3.32e-05	14	92	3	GO:0003964
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH10 DNAH8 DNAH9	7.35e-05	18	92	3	GO:0008569
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-8 ERVK-7	1.19e-04	21	92	3	GO:0035613
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC3 DNAH10 CLU ABCA12 ABCA13 RNF213 MACF1 DNAH8 DNAH9	1.98e-04	441	92	9	GO:0016887
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH10 DNAH8 DNAH9	2.85e-04	28	92	3	GO:0051959
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-8 ERVK-7	6.57e-04	37	92	3	GO:0016891
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH10 DNAH8 DNAH9	6.57e-04	37	92	3	GO:0045505
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-8 ERVK-7	7.10e-04	38	92	3	GO:0034061
GeneOntologyMolecularFunction	ATPase-coupled lipid transmembrane transporter activity	ABCC3 ABCA12	7.40e-04	9	92	2	GO:0034040
GeneOntologyMolecularFunction	structural molecule activity	ERVK-6 DST COL6A6 ERVK-8 MACF1 ERVK-19 NUP62 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	7.86e-04	891	92	12	GO:0005198
GeneOntologyMolecularFunction	peptidase activity	ERVK-6 USP34 ADAM21 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	8.54e-04	654	92	10	GO:0008233
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCC3 DNAH10 CLU ABCA12 ABCA13 RNF213 MACF1 GNAZ DNAH8 DNAH9 RAB27A	8.61e-04	775	92	11	GO:0017111
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-8 ERVK-7	1.24e-03	46	92	3	GO:0016893
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCA12 ABCA13	1.50e-03	49	92	3	GO:0140359
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCC3 DNAH10 CLU ABCA12 ABCA13 RNF213 MACF1 GNAZ DNAH8 DNAH9 RAB27A	1.63e-03	839	92	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCC3 DNAH10 CLU ABCA12 ABCA13 RNF213 MACF1 GNAZ DNAH8 DNAH9 RAB27A	1.64e-03	840	92	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCC3 DNAH10 CLU ABCA12 ABCA13 RNF213 MACF1 GNAZ DNAH8 DNAH9 RAB27A	1.64e-03	840	92	11	GO:0016818
GeneOntologyMolecularFunction	ATP-dependent activity	ABCC3 DNAH10 CLU ABCA12 ABCA13 RNF213 MACF1 DNAH8 DNAH9	2.08e-03	614	92	9	GO:0140657
GeneOntologyMolecularFunction	microtubule minus-end binding	MACF1 TUBGCP5	2.12e-03	15	92	2	GO:0051011
GeneOntologyMolecularFunction	zinc ion binding	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-9 HERC2 ERVK-24 NBR1 SEC23A VAT1	2.61e-03	891	92	11	GO:0008270
GeneOntologyMolecularFunction	ephrin receptor activity	EPHA6 NTRK3	3.41e-03	19	92	2	GO:0005003
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 RBBP8 ERVK-8 ERVK-7	3.62e-03	136	92	4	GO:0004519
GeneOntologyMolecularFunction	microtubule motor activity	DNAH10 DNAH8 DNAH9	4.15e-03	70	92	3	GO:0003777
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-8 ERVK-7	5.81e-03	79	92	3	GO:0004521
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-8 ERVK-7	2.38e-05	13	92	3	GO:0015074
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	3.92e-05	85	92	5	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	3.92e-05	85	92	5	GO:0000768
GeneOntologyBiologicalProcess	syncytium formation	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	4.89e-05	89	92	5	GO:0006949
GeneOntologyCellularComponent	sperm end piece	FSIP2 AKAP4	5.73e-05	3	92	2	GO:0097229
GeneOntologyCellularComponent	9+2 motile cilium	CUL3 FSIP2 AKAP4 DNAH10 CATSPERG DNAH8 DNAH9	8.75e-05	238	92	7	GO:0097729
GeneOntologyCellularComponent	motile cilium	CUL3 FSIP2 AKAP4 DNAH10 SPAG17 CATSPERG DNAH8 DNAH9	1.72e-04	355	92	8	GO:0031514
GeneOntologyCellularComponent	axonemal dynein complex	DNAH10 DNAH8 DNAH9	1.77e-04	25	92	3	GO:0005858
GeneOntologyCellularComponent	perinuclear endoplasmic reticulum	DST CLU OSBPL6	2.77e-04	29	92	3	GO:0097038
GeneOntologyCellularComponent	sperm principal piece	FSIP2 AKAP4 CATSPERG	9.59e-04	44	92	3	GO:0097228
GeneOntologyCellularComponent	outer dynein arm	DNAH8 DNAH9	1.23e-03	12	92	2	GO:0036157
MousePheno	abnormal dorsal spinal root morphology	DST LBX1 CD86	5.54e-06	8	66	3	MP:0003994
MousePheno	short sperm flagellum	FSIP2 AKAP4 DNAH10 SPAG17 DNAH8	1.14e-05	63	66	5	MP:0009239
MousePheno	abnormal sperm fibrous sheath morphology	FSIP2 AKAP4 SPAG17 DNAH8	1.48e-05	32	66	4	MP:0030590
MousePheno	abnormal sperm principal piece morphology	FSIP2 AKAP4 SPAG17 DNAH8	5.84e-05	45	66	4	MP:0009836
MousePheno	decreased chemically-elicited antinociception	ABCC3 GNAZ IL6	9.23e-05	19	66	3	MP:0001982
Domain	Homeobox_KN	PKNOX2 PKNOX1 TGIF2LX MEIS2	7.86e-07	17	82	4	PF05920
Domain	Homeobox_KN_domain	PKNOX2 PKNOX1 TGIF2LX MEIS2	7.86e-07	17	82	4	IPR008422
Domain	PKNOX/Meis_N	PKNOX2 PKNOX1 MEIS2	8.11e-07	5	82	3	IPR032453
Domain	Meis_PKNOX_N	PKNOX2 PKNOX1 MEIS2	8.11e-07	5	82	3	PF16493
Domain	AAA+_ATPase	ABCC3 DNAH10 ABCA12 ABCA13 RNF213 DNAH8 DNAH9	3.28e-06	144	82	7	IPR003593
Domain	AAA	ABCC3 DNAH10 ABCA12 ABCA13 RNF213 DNAH8 DNAH9	3.28e-06	144	82	7	SM00382
Domain	DHC_N1	DNAH10 DNAH8 DNAH9	4.50e-06	8	82	3	PF08385
Domain	Dynein_heavy_dom-1	DNAH10 DNAH8 DNAH9	4.50e-06	8	82	3	IPR013594
Domain	Dynein_heavy_chain_D4_dom	DNAH10 DNAH8 DNAH9	2.87e-05	14	82	3	IPR024317
Domain	Dynein_HC_stalk	DNAH10 DNAH8 DNAH9	2.87e-05	14	82	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH10 DNAH8 DNAH9	2.87e-05	14	82	3	IPR013602
Domain	DHC_N2	DNAH10 DNAH8 DNAH9	2.87e-05	14	82	3	PF08393
Domain	MT	DNAH10 DNAH8 DNAH9	2.87e-05	14	82	3	PF12777
Domain	AAA_8	DNAH10 DNAH8 DNAH9	2.87e-05	14	82	3	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH10 DNAH8 DNAH9	2.87e-05	14	82	3	IPR011704
Domain	AAA_5	DNAH10 DNAH8 DNAH9	2.87e-05	14	82	3	PF07728
Domain	DHC_fam	DNAH10 DNAH8 DNAH9	3.57e-05	15	82	3	IPR026983
Domain	Dynein_heavy_dom	DNAH10 DNAH8 DNAH9	3.57e-05	15	82	3	IPR004273
Domain	Dynein_heavy	DNAH10 DNAH8 DNAH9	3.57e-05	15	82	3	PF03028
Domain	IgC2-like_lig-bd	CSF3R LEPR	1.14e-04	4	82	2	IPR010457
Domain	Lep_receptor_Ig	CSF3R LEPR	1.14e-04	4	82	2	PF06328
Domain	-	DST MACF1	2.82e-04	6	82	2	3.90.1290.10
Domain	GAR	DST MACF1	2.82e-04	6	82	2	PS51460
Domain	-	DST MACF1	2.82e-04	6	82	2	3.30.920.20
Domain	GAS_dom	DST MACF1	2.82e-04	6	82	2	IPR003108
Domain	GAS2	DST MACF1	2.82e-04	6	82	2	PF02187
Domain	GAS2	DST MACF1	2.82e-04	6	82	2	SM00243
Domain	EGF_LAM_2	ATRN STAB2 ATRNL1	3.04e-04	30	82	3	PS50027
Domain	EGF_LAM_1	ATRN STAB2 ATRNL1	3.04e-04	30	82	3	PS01248
Domain	Plectin_repeat	DST MACF1	3.94e-04	7	82	2	IPR001101
Domain	Hematopoietin_rcpt_Gp130_CS	CSF3R LEPR	3.94e-04	7	82	2	IPR003529
Domain	Plectin	DST MACF1	3.94e-04	7	82	2	PF00681
Domain	PLEC	DST MACF1	3.94e-04	7	82	2	SM00250
Domain	EGF_Lam	ATRN STAB2 ATRNL1	4.82e-04	35	82	3	SM00180
Domain	HEMATOPO_REC_L_F2	CSF3R LEPR	5.24e-04	8	82	2	PS01353
Domain	Homeobox	PKNOX2 VAX1 LBX1 PKNOX1 TGIF2LX MEIS2	5.74e-04	234	82	6	PF00046
Domain	HOMEOBOX_1	PKNOX2 VAX1 LBX1 PKNOX1 TGIF2LX MEIS2	6.01e-04	236	82	6	PS00027
Domain	HOX	PKNOX2 VAX1 LBX1 PKNOX1 TGIF2LX MEIS2	6.14e-04	237	82	6	SM00389
Domain	Laminin_EGF	ATRN STAB2 ATRNL1	6.16e-04	38	82	3	IPR002049
Domain	HOMEOBOX_2	PKNOX2 VAX1 LBX1 PKNOX1 TGIF2LX MEIS2	6.42e-04	239	82	6	PS50071
Domain	Homeobox_dom	PKNOX2 VAX1 LBX1 PKNOX1 TGIF2LX MEIS2	6.42e-04	239	82	6	IPR001356
Domain	Hempt_rcpt_S_F1_CS	IL2RG LEPR	6.72e-04	9	82	2	IPR003531
Domain	ABC_A	ABCA12 ABCA13	1.22e-03	12	82	2	IPR026082
Domain	ABC_tran	ABCC3 ABCA12 ABCA13	1.22e-03	48	82	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCA12 ABCA13	1.22e-03	48	82	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCC3 ABCA12 ABCA13	1.30e-03	49	82	3	PS00211
Domain	ABC_transporter-like	ABCC3 ABCA12 ABCA13	1.38e-03	50	82	3	IPR003439
Domain	-	PKNOX2 VAX1 LBX1 PKNOX1 TGIF2LX MEIS2	1.53e-03	283	82	6	1.10.10.60
Domain	EGF_extracell	ATRN STAB2 ATRNL1	2.33e-03	60	82	3	IPR013111
Domain	EGF_2	ATRN STAB2 ATRNL1	2.33e-03	60	82	3	PF07974
Domain	ZZ	HERC2 NBR1	2.78e-03	18	82	2	PF00569
Domain	ZF_ZZ_2	HERC2 NBR1	2.78e-03	18	82	2	PS50135
Domain	ZF_ZZ_1	HERC2 NBR1	2.78e-03	18	82	2	PS01357
Domain	CH	DST MACF1 IQGAP3	2.93e-03	65	82	3	SM00033
Domain	Znf_ZZ	HERC2 NBR1	3.10e-03	19	82	2	IPR000433
Domain	ZnF_ZZ	HERC2 NBR1	3.10e-03	19	82	2	SM00291
Domain	Homeodomain-like	PKNOX2 VAX1 LBX1 PKNOX1 TGIF2LX MEIS2	3.40e-03	332	82	6	IPR009057
Domain	CH	DST MACF1 IQGAP3	3.61e-03	70	82	3	PF00307
Domain	-	DST MACF1 IQGAP3	3.76e-03	71	82	3	1.10.418.10
Domain	P-loop_NTPase	ABCC3 MYO15B DNAH10 ABCA12 ABCA13 RNF213 GNAZ DNAH8 DNAH9 RAB27A	3.92e-03	848	82	10	IPR027417
Domain	CH	DST MACF1 IQGAP3	4.07e-03	73	82	3	PS50021
Domain	CH-domain	DST MACF1 IQGAP3	4.39e-03	75	82	3	IPR001715
Domain	Actinin_actin-bd_CS	DST MACF1	4.54e-03	23	82	2	IPR001589
Domain	Spectrin	DST MACF1	4.54e-03	23	82	2	PF00435
Domain	ACTININ_2	DST MACF1	4.54e-03	23	82	2	PS00020
Domain	ACTININ_1	DST MACF1	4.54e-03	23	82	2	PS00019
Pathway	WP_FOXP3_IN_COVID19	CD86 IL2RG IL6	2.61e-05	15	56	3	M42573
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	1.01e-10	12	94	5	14557543
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	1.93e-10	94	94	8	21542922
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-19 ERVK-7 ERVK-21	2.50e-10	5	94	4	12629516
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-24	7.63e-08	4	94	3	10469592
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-25 ERVK-9 ERVK-24	1.49e-07	18	94	4	18664271
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-19 ERVK-9	3.80e-07	6	94	3	15063128
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-19 ERVK-21	2.26e-06	10	94	3	12970426
Pubmed	Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors.	PKNOX2 PKNOX1 MEIS2	3.11e-06	11	94	3	18787068
Pubmed	A gene expression map of human chromosome 21 orthologues in the mouse.	URB1 RRP1B ETS2 PKNOX1 HUNK DOP1B	4.68e-06	158	94	6	12466855
Pubmed	Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.	PKNOX2 PKNOX1 MEIS2	5.36e-06	13	94	3	16847320
Pubmed	Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development.	PKNOX2 PKNOX1 MEIS2	5.36e-06	13	94	3	17049510
Pubmed	Human chromosome 21 gene expression atlas in the mouse.	URB1 RRP1B ETS2 PKNOX1 HUNK DOP1B	5.60e-06	163	94	6	12466854
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	7.23e-06	2	94	2	11002341
Pubmed	Colitis in mice lacking the common cytokine receptor gamma chain is mediated by IL-6-producing CD4+ T cells.	IL2RG IL6	7.23e-06	2	94	2	15825075
Pubmed	p62 and NBR1 functions are dispensable for aggrephagy in mouse ESCs and ESC-derived neurons.	NUP62 NBR1	7.23e-06	2	94	2	37620146
Pubmed	Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo.	RNF123 RNF213	7.23e-06	2	94	2	26126547
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	7.23e-06	2	94	2	9060628
Pubmed	Protein C-ets-2 epigenetically suppresses TLRs-induced interleukin 6 production in macrophages.	ETS2 IL6	7.23e-06	2	94	2	31810605
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	7.23e-06	2	94	2	9460924
Pubmed	Genetic analysis of attractin homologs.	ATRN ATRNL1	7.23e-06	2	94	2	18064672
Pubmed	Dysregulation of Rnf 213 gene contributes to T cell response via antigen uptake, processing, and presentation.	RNF123 RNF213	7.23e-06	2	94	2	33973242
Pubmed	Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells.	PKNOX2 PKNOX1 MEIS2	8.50e-06	15	94	3	23756022
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ATRN USP34 RNF123 DST CLU ATRNL1 ETS2 PKNOX1 MACF1 MIGA1 HUNK HERC2 TUBGCP5 DOP1B	9.09e-06	1285	94	14	35914814
Pubmed	Interaction of IL-6 and TNF-α contributes to endothelial dysfunction in type 2 diabetic mouse hearts.	LEPR IL6	2.16e-05	3	94	2	29095915
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	2.16e-05	3	94	2	12399109
Pubmed	Effects of Components of PM2.5 Collected in Japan on the Respiratory and Immune Systems.	CD86 IL6	2.16e-05	3	94	2	28056587
Pubmed	Proinflammatory biomarkers' level and functional genetic polymorphisms in periprosthetic joint infection.	CSF3R IL6	2.16e-05	3	94	2	29305046
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-9	2.16e-05	3	94	2	9971820
Pubmed	Prep2: cloning and expression of a new prep family member.	PKNOX2 PKNOX1	2.16e-05	3	94	2	12412021
Pubmed	Whole-exome sequencing identifies mutations in FSIP2 as a recurrent cause of multiple morphological abnormalities of the sperm flagella.	FSIP2 AKAP4	2.16e-05	3	94	2	30137358
Pubmed	A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production.	IL2RG IL6	2.16e-05	3	94	2	28077418
Pubmed	Associations of TNF-α and IL-6 polymorphisms with osteoporosis through joint effects and interactions with LEPR gene in Taiwan: Taichung Community Health Study for Elders (TCHS-E).	LEPR IL6	2.16e-05	3	94	2	27401061
Pubmed	Pulmonary responses to subacute ozone exposure in obese vs. lean mice.	LEPR IL6	2.16e-05	3	94	2	19745193
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	2.16e-05	3	94	2	10516026
Pubmed	Common variants of IL6, LEPR, and PBEF1 are associated with obesity in Indian children.	LEPR IL6	2.16e-05	3	94	2	22228719
Pubmed	Homozygous loss-of-function mutations in FSIP2 cause male infertility with asthenoteratospermia.	FSIP2 AKAP4	2.16e-05	3	94	2	30745215
Pubmed	Gene-gene interactions among CX3CL1, LEPR and IL-6 related to coronary artery disease in Chinese Han population.	LEPR IL6	2.16e-05	3	94	2	26191329
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	SZT2 ABCA13 PKHD1 RNF213 IQGAP3 STT3A	2.24e-05	208	94	6	33230847
Pubmed	The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells.	PKNOX2 PKNOX1 MEIS2	3.71e-05	24	94	3	20826531
Pubmed	Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice.	IL2RG IL6	4.32e-05	4	94	2	38433905
Pubmed	RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells.	IL2RG IL6	4.32e-05	4	94	2	19029903
Pubmed	Identification of new molecular alterations in fatal familial insomnia.	CSF3R IL6	4.32e-05	4	94	2	27056979
Pubmed	Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study.	LEPR IL6	4.32e-05	4	94	2	26558825
Pubmed	Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.	DNAH10 DNAH9	4.32e-05	4	94	2	11175280
Pubmed	MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse.	LEPR VAT1	4.32e-05	4	94	2	29637443
Pubmed	Leptin stimulates interleukin-6 production via janus kinase 2/signal transducer and activator of transcription 3 in rheumatoid synovial fibroblasts.	LEPR IL6	4.32e-05	4	94	2	23622344
Pubmed	Comparison of the positional cloning methods used to isolate the BRCA1 gene.	NBR1 VAT1	4.32e-05	4	94	2	7581362
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	4.32e-05	4	94	2	8954775
Pubmed	Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis.	LEPR IL6	4.32e-05	4	94	2	28508871
Pubmed	Systemic levels of G-CSF and interleukin-6 determine the angiogenic potential of bone marrow resident monocytes.	CSF3R IL6	4.32e-05	4	94	2	20354107
Pubmed	Association of Alzheimer's Disease with Genetic Variants of Apolipoprotein E, Clusterin, TNF-α, and IL-6 Among Elderly Saudis.	CLU IL6	4.32e-05	4	94	2	35135450
Pubmed	Host genetics, steatosis and insulin resistance among African Americans and Caucasian Americans with hepatitis C virus genotype-1 infection.	LEPR IL6	4.32e-05	4	94	2	19401628
Pubmed	Circulating levels of IL-1B+IL-6 cause ER stress and dysfunction in islets from prediabetic male mice.	LEPR IL6	4.32e-05	4	94	2	23836031
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-19	4.32e-05	4	94	2	7983737
Pubmed	Identification of a conserved family of Meis1-related homeobox genes.	MEIS2 MEIS3P1	4.32e-05	4	94	2	9049632
Pubmed	Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death.	DST NTRK3 MEIS2	4.75e-05	26	94	3	26857994
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	CUL3 RNF123 DST RNF213 MACF1 HERC2 COPS2 NBR1	4.97e-05	481	94	8	28190767
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	RNF213 MACF1 HERC2 SEC23A	5.53e-05	76	94	4	27542412
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	CUL3 RRP1B CLU ABCA13 SERPING1 MACF1 DNAH9	5.78e-05	361	94	7	26167880
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	7.19e-05	5	94	2	11401426
Pubmed	Adipokine genes and prostate cancer risk.	LEPR IL6	7.19e-05	5	94	2	19035456
Pubmed	Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release.	LEPR IL6	7.19e-05	5	94	2	27870582
Pubmed	Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.	LEPR IL6	7.19e-05	5	94	2	22037645
Pubmed	A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.	FSIP2 AKAP4	7.19e-05	5	94	2	12606363
Pubmed	The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice.	NTRK3 MEIS2	7.19e-05	5	94	2	36418415
Pubmed	Genotype x nutrient association of common polymorphisms in obesity-related genes with food preferences and time structure of energy intake.	LEPR IL6	7.19e-05	5	94	2	19747414
Pubmed	Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway.	LEPR IL6	7.19e-05	5	94	2	21459325
Pubmed	Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development.	CPHXL CPHXL2	7.19e-05	5	94	2	26360614
Pubmed	Genetic and phenotypic studies of the dark-like mutant mouse.	ATRN ATRNL1	7.19e-05	5	94	2	18821597
Pubmed	Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells.	CD86 IL6	7.19e-05	5	94	2	21690252
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	CUL3 PPP2R2B RNF123 HERC2	9.38e-05	87	94	4	17148452
Pubmed	MEIS proteins as partners of the TLX1/HOX11 oncoprotein.	PKNOX1 MEIS2	1.08e-04	6	94	2	19559479
Pubmed	Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages.	LEPR IL6	1.08e-04	6	94	2	26481668
Pubmed	Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and [corrected] CD40-induced cytokine production.	CD86 IL6	1.08e-04	6	94	2	18322171
Pubmed	A model for modulation of leptin activity by association with clusterin.	CLU LEPR	1.08e-04	6	94	2	12824284
Pubmed	The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy.	LEPR IL6	1.08e-04	6	94	2	22479352
Pubmed	Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A.	CUL3 IL2RG	1.08e-04	6	94	2	26320660
Pubmed	The capacity of Th2 lymphocytes to deliver B-cell help requires expression of the transcription factor STAT3.	IL2RG IL6	1.08e-04	6	94	2	23504518
Pubmed	Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.	DIP2B LEPR IL6	1.18e-04	35	94	3	23969696
Pubmed	Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice.	IL2RG IL6	1.50e-04	7	94	2	27723723
Pubmed	Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15.	CUL3 PPP2R2B	1.50e-04	7	94	2	23135275
Pubmed	Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon.	PKNOX1 MEIS2	1.50e-04	7	94	2	17178831
Pubmed	Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome.	CUL3 COPS2	1.50e-04	7	94	2	32047038
Pubmed	Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity.	PKNOX1 MEIS2	1.50e-04	7	94	2	20413611
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH8 DNAH9	1.50e-04	7	94	2	31178125
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ATRN USP34 URB1 ATRNL1	1.94e-04	105	94	4	9628581
Pubmed	Mcl-1 is essential for the survival of plasma cells.	CD86 IL6	2.00e-04	8	94	2	23377201
Pubmed	Genetic analysis of Down syndrome-associated heart defects in mice.	URB1 HUNK	2.00e-04	8	94	2	21442329
Pubmed	Pollen-induced oxidative stress influences both innate and adaptive immune responses via altering dendritic cell functions.	CD86 IL6	2.00e-04	8	94	2	20118277
Pubmed	Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study.	LEPR IL6	2.00e-04	8	94	2	18249219
Pubmed	Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.	IL2RG IL6	2.00e-04	8	94	2	24336249
Pubmed	Bridging expressed sequence alignments through targeted cDNA sequencing.	DIP2B SZT2	2.00e-04	8	94	2	15028280
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	PPP2R2B RRP1B SZT2 NUP62 HERC2 TUBGCP5 IQGAP3 VAT1	2.43e-04	606	94	8	36538041
Pubmed	Characterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activity.	CUL3 COPS2	2.57e-04	9	94	2	22013077
Pubmed	Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.	CUL3 LEPR	2.57e-04	9	94	2	27708159
Pubmed	Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.	PKNOX1 MEIS2	2.57e-04	9	94	2	12183364
Pubmed	Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells.	CSF3R IL2RG	2.57e-04	9	94	2	26678340
Pubmed	Anchoring and scaffold proteins for kinases and phosphatases.	AKAP4 AKAP10	2.57e-04	9	94	2	9238861
Pubmed	A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.	NBR1 VAT1	2.57e-04	9	94	2	7545954
Pubmed	Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis.	IL2RG LEPR	2.57e-04	9	94	2	37185464
Interaction	PBX2 interactions	CUL3 PKNOX2 RNF123 PKNOX1 NUP62 MEIS2	3.42e-06	97	85	6	int:PBX2
Cytoband	Ensembl 112 genes in cytogenetic band chr21q22	URB1 RRP1B ETS2 PKNOX1 HUNK DOP1B	1.23e-04	377	93	6	chr21q22
GeneFamily	TALE class homeoboxes and pseudogenes	PKNOX2 PKNOX1 TGIF2LX MEIS2 MEIS3P1	1.78e-08	26	58	5	526
GeneFamily	Dyneins, axonemal	DNAH10 DNAH8 DNAH9	2.06e-05	17	58	3	536
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	2.80e-04	8	58	2	939
GeneFamily	ATP binding cassette subfamily A	ABCA12 ABCA13	8.98e-04	14	58	2	805
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	HERC2 NBR1	1.50e-03	18	58	2	91
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP4 AKAP10	3.88e-03	29	58	2	396
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ATRN ATRNL1	7.65e-03	41	58	2	1298
Coexpression	TOMLINS_PROSTATE_CANCER_DN	DST CLU MEIS2 SEC23A	8.21e-06	40	84	4	M11504
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	FSIP2 DIP2B PPP2R2B COL6A6 NTRK3 OSBPL6 ETS2 ZYG11B GIGYF1 GNAZ SPAG17 CATSPERG FAM81A DOP1B	1.05e-05	1106	84	14	M39071
Coexpression	DEMAGALHAES_AGING_UP	CLU SERPING1 RNF213 VAT1	2.75e-05	54	84	4	M2144
Coexpression	GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_UP	PKNOX2 PPP2R2B ABCA12 NUP62 IL2RG VAT1	4.17e-05	197	84	6	M8159
Coexpression	HOLLMANN_APOPTOSIS_VIA_CD40_UP	USP34 DST CD86 ETS2 COPS2 MEIS2	4.93e-05	203	84	6	M9695
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP2R2B EPHA6 DNAH10 ABCA13 NTRK3 PKHD1 DNAH9	2.91e-08	162	86	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 DNAH10 ABCA12 ABCA13 PKHD1 SPAG17 DNAH9	6.98e-08	184	86	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 DNAH10 ABCA12 ABCA13 PKHD1 SPAG17 DNAH9	6.98e-08	184	86	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 DNAH10 ABCA12 ABCA13 PKHD1 SPAG17 DNAH9	6.98e-08	184	86	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNAH10 LRRC51 PIH1D2 GNAZ SPAG17 DNAH9 FAM81A	7.80e-08	187	86	7	1bba994aaaa9825b54aaeaff3829850267bc4602
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNAH10 LRRC51 PIH1D2 GNAZ SPAG17 DNAH9 FAM81A	7.80e-08	187	86	7	d6ac351e7aeba98851d308c14ac395044fe4fbbb
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B ABCC3 CD86 MED12L SERPING1 MACF1 STT3A	8.38e-08	189	86	7	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNAH10 LRRC51 PIH1D2 GNAZ SPAG17 DNAH9 FAM81A	8.38e-08	189	86	7	a28e0922e10013ae79266f6a3f9305e6ee614d8b
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B ABCC3 CD86 MED12L SERPING1 MACF1 STT3A	8.38e-08	189	86	7	3ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B ABCC3 CD86 MED12L SERPING1 MACF1 STT3A	8.38e-08	189	86	7	875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCell	facs-Brain_Myeloid-Striatum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIP2B ABCC3 CD86 MED12L SERPING1 MACF1 STT3A	8.38e-08	189	86	7	97ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 CLU ABCA13 OSBPL6 SPAG17 DNAH9 C1orf141	9.01e-08	191	86	7	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 CLU ABCA13 OSBPL6 SPAG17 DNAH9 C1orf141	9.01e-08	191	86	7	c4b223b33c020a064f576711a3d700eb60a2d737
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST CSF3R RRP1B MED12L SERPING1 MACF1 HERC2	1.04e-07	195	86	7	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	WWC3 CLU ETS2 SERPING1 RNF213 MEIS2 VAT1	1.23e-07	200	86	7	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH10 ABCA13 PIH1D2 OSBPL6 SPAG17 DNAH9 C1orf141	1.23e-07	200	86	7	ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Ciliated\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	DNAH10 ABCA13 PIH1D2 OSBPL6 SPAG17 DNAH9 C1orf141	1.23e-07	200	86	7	a521cf837cadf280505ff9d7e641a205af7d6513
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH10 ABCA13 PIH1D2 OSBPL6 SPAG17 DNAH9 C1orf141	1.23e-07	200	86	7	918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-3\|TCGA-Breast / Sample_Type by Project: Shred V9	STAB2 DST ETS2 RFX2 LEPR IL6	2.75e-07	137	86	6	3218c787a6b087f74b0804cec14b5ebb713391b7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CSF3R PIH1D2 GPAT3 ETS2 RFX2 CYTH4	7.91e-07	164	86	6	10741c7706a37b24aa08a300b27d60d6b8600167
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CSF3R PIH1D2 GPAT3 ETS2 RFX2 CYTH4	7.91e-07	164	86	6	7077683afee91828ad2b95e0f81c2b27aae0f831
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 ABCA12 ABCA13 PKHD1 DNAH9 IL6	9.42e-07	169	86	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC19 DNAH10 PIH1D2 SPAG17 DNAH9 FAM81A	1.19e-06	176	86	6	ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCell	Ciliated_cells-A-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	DNAH10 PIH1D2 OSBPL6 SPAG17 DNAH9 C1orf141	1.19e-06	176	86	6	1c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNAH10 LRRC51 PIH1D2 SPAG17 DNAH9 FAM81A	1.32e-06	179	86	6	d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNAH10 LRRC51 PIH1D2 SPAG17 DNAH9 FAM81A	1.32e-06	179	86	6	8a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCell	facs-Skin-Telogen-3m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLU RBBP8 ETS2 IL2RG FAM81A RAB27A	1.75e-06	188	86	6	8cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 PIH1D2 GNAZ SPAG17 DNAH9 FAM81A	1.81e-06	189	86	6	28c750ac56e3861fe7280e32839a4d8ce8bd8692
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 PIH1D2 GNAZ SPAG17 DNAH9 FAM81A	1.81e-06	189	86	6	efee01edd171bf569267b672fab05c421de6c92d
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CSF3R GLT1D1 CD86 GPAT3 ETS2 CYTH4	1.86e-06	190	86	6	ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH10 ABCA13 OSBPL6 SPAG17 DNAH9 C1orf141	1.92e-06	191	86	6	7b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	DNAH10 ABCA13 OSBPL6 SPAG17 DNAH9 C1orf141	1.92e-06	191	86	6	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH10 ABCA13 OSBPL6 SPAG17 DNAH9 C1orf141	1.92e-06	191	86	6	b4e335e798c9617356b8e24412f9270c42dce656
ToppCell	Control-Epithelial-Ciliated\|Control / Disease group,lineage and cell class （2021.01.30）	DNAH10 ABCA13 OSBPL6 SPAG17 DNAH9 C1orf141	1.92e-06	191	86	6	cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	DNAH10 ABCA13 OSBPL6 SPAG17 DNAH9 C1orf141	1.92e-06	191	86	6	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PIH1D2 OSBPL6 SPAG17 DNAH9	2.04e-06	193	86	6	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CSF3R DNAH10 ABCA13 MED12L IQGAP3 VAT1	2.04e-06	193	86	6	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CSF3R DNAH10 ABCA13 MED12L IQGAP3 VAT1	2.10e-06	194	86	6	23318a1b55895b5166c6151f488a94a09b4627ff
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 PIH1D2 SPAG17 DNAH9 C1orf141	2.10e-06	194	86	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 ABCA13 PIH1D2 SPAG17 DNAH9 C1orf141	2.16e-06	195	86	6	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH10 PIH1D2 OSBPL6 SPAG17 RFX2 DNAH9	2.16e-06	195	86	6	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	BL-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 PIH1D2 OSBPL6 SPAG17 DNAH9 C1orf141	2.16e-06	195	86	6	07a6bcef6af93ed87df455dee624037cb75e011a
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 PIH1D2 OSBPL6 SPAG17 DNAH9 C1orf141	2.29e-06	197	86	6	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	distal-Epithelial-Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH10 ABCA13 PIH1D2 SPAG17 DNAH9 C1orf141	2.43e-06	199	86	6	6ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST ETS2 RNF213 MACF1 MEIS2 VAT1	2.50e-06	200	86	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Biopsy_Control_(H.)-Epithelial-Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	DNAH10 PIH1D2 OSBPL6 SPAG17 DNAH9 C1orf141	2.50e-06	200	86	6	9ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 DST RNF213 MACF1 LEPR MEIS2	2.50e-06	200	86	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DST ETS2 RNF213 MACF1 MEIS2 VAT1	2.50e-06	200	86	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	severe-immature_Neutrophil\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CSF3R ABCA13 MED12L RAB27A DOP1B VAT1	2.50e-06	200	86	6	a9b87accdaa6956116ab82427e1330e8f007ef94
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CSF3R CD86 IQGAP3 IL6 CYTH4	4.80e-06	127	86	5	0750743574c2fca8df07e11d73e8b94579209609
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	DNAH10 ABCA13 SPAG17 RFX2 DNAH9	1.11e-05	151	86	5	8216462e723fec2797387929dde095370947e10a
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DST DNAH10 GPAT3 MED12L FAM81A	1.19e-05	153	86	5	91e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DST DNAH10 GPAT3 MED12L FAM81A	1.19e-05	153	86	5	f17f62646633cf95c810dcd5328978058741b276
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD86 PIH1D2 GPAT3 ETS2 SERPING1	1.39e-05	158	86	5	216b3f482daa2d0d7fcaf5a8559e3ccbdb8e110d
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD86 PIH1D2 GPAT3 ETS2 SERPING1	1.39e-05	158	86	5	9712bb8b1bacb8a38c99a22bc2babec5d5160e2a
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ABCC3 CSF3R CD86 IL6 CYTH4	1.43e-05	159	86	5	41d2c1e71f6983156f8cc8ec5f69e025e5700f46
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CSF3R PIH1D2 GPAT3 ETS2 CYTH4	1.52e-05	161	86	5	4362fe0c151f49eae7372b9673bac64d980a8389
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AKAP4 GLT1D1 LRRC51 SPAG17 RFX2	1.66e-05	164	86	5	d9531848105d606adedde65426177cf851140e31
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	CSF3R PIH1D2 OSBPL6 SPAG17 DNAH9	1.81e-05	167	86	5	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FSIP2 PPP2R2B ABCA13 PKHD1 HUNK	1.97e-05	170	86	5	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ABCA13 RBBP8 PKHD1 IL6	2.09e-05	172	86	5	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ABCA13 RBBP8 PKHD1 IL6	2.09e-05	172	86	5	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 ABCA13 OSBPL6 SPAG17 DNAH9	2.15e-05	173	86	5	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R2B EPHA6 CLU MED12L HUNK	2.21e-05	174	86	5	46bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell	CTRL-Lymphoid-pDC\|Lymphoid / Disease state, Lineage and Cell class	RNF123 GLT1D1 ETS2 MED12L SERPING1	2.21e-05	174	86	5	ff4315e9fad198cc323fc987deb8652da137cf98
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	GLT1D1 OSBPL6 DNAH9 BBS10 VAT1	2.27e-05	175	86	5	7de1023161233b64f11e130881c742f4cf2bff65
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ABCA13 PIH1D2 OSBPL6 SPAG17 C1orf141	2.40e-05	177	86	5	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PKNOX2 ABCC3 ATRNL1 PKHD1 HUNK	2.46e-05	178	86	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	PKNOX2 ABCC3 DST ATRNL1 MEIS2	2.53e-05	179	86	5	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R2B EPHA6 WWC3 MED12L HUNK	2.53e-05	179	86	5	55bc69f107fc710db7617c428575792adfdbbcc1
ToppCell	Ciliated_cells-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	DNAH10 OSBPL6 SPAG17 DNAH9 C1orf141	2.60e-05	180	86	5	bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R2B EPHA6 WWC3 MED12L HUNK	2.81e-05	183	86	5	83592c332b1e82673f993d37c7f480befdc3dcda
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 NTRK3 HTR3B RFX2 MEIS2	2.81e-05	183	86	5	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	facs-Lung-EPCAM-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 PIH1D2 SPAG17 DNAH9 FAM81A	2.89e-05	184	86	5	afb11ab301ef9801333dbb53ccff4bd0d44f1677
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAH10 PIH1D2 SPAG17 DNAH9 FAM81A	2.89e-05	184	86	5	a411c0bcb283534a1c15f22473c46b7d87e01294
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 NTRK3 HTR3B RFX2 MEIS2	2.89e-05	184	86	5	30fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 NTRK3 HTR3B RFX2 MEIS2	2.89e-05	184	86	5	96926efa220f03d0787322c9519bb9e8f64f74d0
ToppCell	megakaryocytic\|World / Lineage and Cell class	ABCC3 CLU MED12L OVOS2 GNAZ	2.89e-05	184	86	5	b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CSF3R CLU GPAT3 MEIS2 VAT1	3.04e-05	186	86	5	de55471dd5c842026b409cfebf67fe32f079a011
ToppCell	COVID_vent-Myeloid-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	DST CD86 GPAT3 ETS2 SI	3.04e-05	186	86	5	63a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CSF3R ETS2 PKHD1 SPAG17 DNAH8	3.04e-05	186	86	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	COVID_vent-Myeloid-Dendritic-cDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	DST CD86 GPAT3 ETS2 SI	3.04e-05	186	86	5	39457a7b43537f2c3e221f9375c95d4515424d7d
ToppCell	PND14-Epithelial-Epithelial_Airway\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRRC51 PIH1D2 OSBPL6 SPAG17 DNAH9	3.12e-05	187	86	5	1399c703505211c510b3f14c7a2aa9930566c473
ToppCell	21-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	DNAH10 PIH1D2 OSBPL6 SPAG17 DNAH9	3.12e-05	187	86	5	1a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CSF3R GLT1D1 CLU GPAT3 MEIS2	3.20e-05	188	86	5	36ff615154d6d9e3ba6ccb73a0f11574bcbf5ece
ToppCell	multiciliated\|World / shred by cell class for bronchial biopsy	DNAH10 PIH1D2 RFX2 DNAH9 C1orf141	3.20e-05	188	86	5	6833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell	droplet-Lung-1m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRC51 OSBPL6 SPAG17 DNAH9 FAM81A	3.20e-05	188	86	5	bc0b9ba8ae88e8a89e98b446584ed39606e4229e
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RBBP8 PKHD1 HUNK SPAG17 FAM81A	3.20e-05	188	86	5	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	droplet-Lung-1m-Epithelial-airway_epithelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRC51 OSBPL6 SPAG17 DNAH9 FAM81A	3.20e-05	188	86	5	50994e304c719f2f3c3232e48141e2dd15c96612
ToppCell	droplet-Lung-1m-Epithelial-airway_epithelial-lung_ciliated_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRC51 OSBPL6 SPAG17 DNAH9 FAM81A	3.20e-05	188	86	5	a7b7ba56603a8a50869b41902aed6a9ab1c5c021
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAH10 LRRC51 PIH1D2 SPAG17 DNAH9	3.28e-05	189	86	5	057d7a03fdbe779122b203619a6f947f49b84d28
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP2R2B CLU ABCA13 FAM81A RAB27A	3.28e-05	189	86	5	e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRRC51 PIH1D2 OSBPL6 SPAG17 DNAH9	3.28e-05	189	86	5	02c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRRC51 PIH1D2 OSBPL6 SPAG17 DNAH9	3.28e-05	189	86	5	164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCell	PND10-Epithelial-Epithelial_Airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRRC51 PIH1D2 OSBPL6 SPAG17 DNAH9	3.28e-05	189	86	5	407d8a59969d83f014600aae1a55092283a13970
ToppCell	Epithelial-D_(Ciliated)\|World / shred on cell class and cell subclass (v4)	DNAH10 PIH1D2 OSBPL6 SPAG17 DNAH9	3.28e-05	189	86	5	0bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP2R2B CLU ABCA13 FAM81A RAB27A	3.28e-05	189	86	5	ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH10 PIH1D2 SPAG17 DNAH9 C1orf141	3.28e-05	189	86	5	a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAH10 LRRC51 PIH1D2 SPAG17 DNAH9	3.28e-05	189	86	5	9f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCell	hematopoetic_progenitors-CD34+_HSC\|World / Lineage and Cell class	CSF3R CLU ETS2 MED12L SERPING1	3.28e-05	189	86	5	51ff31c9cf5eff98ad01c0455dc4ae4908713575
Disease	restless legs syndrome (implicated_via_orthology)	PKNOX2 MEIS2 MEIS3P1	1.15e-06	8	82	3	DOID:0050425 (implicated_via_orthology)
Disease	leukemia (implicated_via_orthology)	PKNOX2 MEIS2 MEIS3P1	1.94e-05	19	82	3	DOID:1240 (implicated_via_orthology)
Disease	conjunctival disease (is_marker_for)	CLU IL6	2.28e-05	3	82	2	DOID:4251 (is_marker_for)
Disease	non-alcoholic steatohepatitis (is_implicated_in)	LEPR IL6	1.14e-04	6	82	2	DOID:0080547 (is_implicated_in)
Disease	cerebrospinal fluid clusterin measurement	DST ABCA13 IL6	1.27e-04	35	82	3	EFO_0007657
Disease	acute myeloid leukemia (is_marker_for)	ABCC3 CD86 IL6	3.48e-04	49	82	3	DOID:9119 (is_marker_for)
Disease	macular retinal edema (is_marker_for)	CLU IL6	4.94e-04	12	82	2	DOID:4449 (is_marker_for)
Disease	Headache	RNF213 MACF1 IL6	7.63e-04	64	82	3	HP_0002315
Disease	depressive disorder (is_implicated_in)	HTR3B IL6	1.01e-03	17	82	2	DOID:1596 (is_implicated_in)
Disease	renal fibrosis (implicated_via_orthology)	CLU LEPR	1.01e-03	17	82	2	DOID:0050855 (implicated_via_orthology)
Disease	pre-eclampsia (biomarker_via_orthology)	LEPR IL6	1.01e-03	17	82	2	DOID:10591 (biomarker_via_orthology)
Disease	non-alcoholic fatty liver disease (is_implicated_in)	LEPR IL6	1.13e-03	18	82	2	DOID:0080208 (is_implicated_in)
Disease	Alzheimer disease, polygenic risk score	FSIP2 RNF123 DST CLU PKHD1 AKAP10 GIGYF1	1.24e-03	586	82	7	EFO_0030082, MONDO_0004975
Disease	progression free survival, ovarian serous carcinoma	ABCA13 IQGAP3	1.70e-03	22	82	2	EFO_0004920, EFO_1001516
Disease	information processing speed	ATRNL1 PKNOX1 RFX2	1.73e-03	85	82	3	EFO_0004363
Disease	Albuminuria	LEPR IL6	2.02e-03	24	82	2	C0001925
Disease	Bipolar Disorder	LBX1 ABCA13 AKAP10 HTR3B DNAH8 IL6	2.15e-03	477	82	6	C0005586
Disease	vital capacity	CUL3 USP34 DIP2B DST RBBP8 OSBPL6 MIGA1 LEPR MEIS2 STT3A	2.22e-03	1236	82	10	EFO_0004312
Disease	acute necrotizing pancreatitis (biomarker_via_orthology)	SERPING1 IL6	2.37e-03	26	82	2	DOID:0080998 (biomarker_via_orthology)
Disease	chronic obstructive pulmonary disease (is_marker_for)	CD86 LEPR IL6	2.53e-03	97	82	3	DOID:3083 (is_marker_for)
Disease	Alzheimer disease, age at onset	DST SZT2 CLU OSBPL6 HERC2	2.71e-03	343	82	5	EFO_0004847, MONDO_0004975
Disease	acute myocardial infarction (biomarker_via_orthology)	SERPING1 IL6	2.75e-03	28	82	2	DOID:9408 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NNLIFIWGNFLLQSS	CATSPERG	486	Q6ZRH7
FVANIQASVSQWLQN	EXOC3L1	381	Q86VI1
INLWNFEITNQSFNI	PPP2R2B	196	Q00005
LWNSQSSIDQKLANQ	ERVK-19	511	O71037
LWNSQSSIDQKLANQ	ERVK-8	511	Q902F8
WNSQSSIDQKLANQI	ERVK-9	511	Q9UKH3
LENRSWNTLYNFSQN	C1orf141	306	Q5JVX7
KWTNQLNSLNQAVVS	COPS2	426	P61201
SLQNNQDVSFENIQW	RBBP8	641	Q99708
QKQLQAVLQWIAASQ	AKAP4	771	Q5JQC9
LQFWLAADNFQSQLA	AKAP10	406	O43572
LNDFSQWKQISLSQL	ADAM21	276	Q9UKJ8
AVWQLLSSFPNVFQN	ABCA12	261	Q86UK0
VWSQLQSISNYLQTQ	HTR3B	381	O95264
NLINNLAGNSQEAAW	ABCA13	2211	Q86UQ4
ANLNLVQALRQFLWS	CYTH4	136	Q9UIA0
QNQSLSELVVFWQDQ	CD86	46	P42081
ILNSEAQFQTSQFWI	BBS10	276	Q8TAM1
LTNEQSFLNVRNWIS	RAB27A	101	P51159
SNQILSARSWLQQEQ	FAM81A	226	Q8TBF8
QQAWIQNCTLQENVL	ABCC3	696	O15438
QLSLETWNYSQNTNI	ANKRD31	1486	Q8N7Z5
EFLLLGFSSWQQQQV	OR1F12P	11	Q8NHA8
GFSSWQQQQVLLFAL	OR1F12P	16	Q8NHA8
LTSLQNQVNQILSNW	MED12L	1486	Q86YW9
RQQQQEAWLSSASLQ	GIGYF1	971	O75420
TNLNWTNVHAINLTL	NTRK3	256	Q16288
LTQWNGLINKYINSQ	HERC2	2156	O95714
NLTQFQTVEAQLKQW	DST	4626	Q03001
QLQLNTIKTNWDTFN	DST	4926	Q03001
TGLTILQVNNWFINA	MEIS2	316	O14770
FINASKNFNLNITWA	ATRN	1196	O75882
EWQRALNFQQAISAL	DOP1B	1471	Q9Y3R5
TLNKVFASQWLNARQ	DCAF12L2	96	Q5VW00
DWQFSTQQIGQLFQK	FSIP2	3656	Q5CZC0
LWATNEFSLVNVNLQ	ETS2	116	P15036
VLATNNWGALNQSKQ	DNAH8	66	Q96JB1
QVIENWTNQNLSFAA	DNAH8	1416	Q96JB1
SAALQQSLQNAESWI	DIP2B	161	Q9P265
QSLQNAESWINRSIQ	DIP2B	166	Q9P265
NSLQEFINWLTLAEQ	MACF1	2576	O94854
NSLVFQQIDANWNIQ	LEPR	116	P48357
TWQNVSFLNVQLQEA	TUBGCP5	751	Q96RT8
FLQQATQVNAWDRTL	NUP62	351	P37198
QWQNVTSFRNITQLS	OVOS2	156	Q6IE36
TSNINLWNILRNNIG	OSBPL6	566	Q9BZF3
LWNSQSSIDQKLANQ	ERVK-7	1271	P63135
FLSWNDLQATVSQVN	IQGAP3	501	Q86VI3
EFQNSLQEFINWLTL	MACF1	6446	Q9UPN3
RNELFSQLVAQLWQN	MYO15B	551	Q96JP2
NNNWFINTSLILFLN	GNAZ	256	P19086
WNSQSSIDQKLANQI	ERVK-24	401	P61566
LWNSQSSIDQKLANQ	ERVK-25	511	P61570
LWNSQSSIDQKLANQ	ERVK-6	511	Q69384
WNSQSSIDQKLANQI	ERVK-7	401	P61567
AFNWNTFLQRSEINQ	GLT1D1	146	Q96MS3
LVSWNLLTRTNVNFQ	GPAT3	121	Q53EU6
SFCLSLLQEQQQNDW	CPHXL2	271	A0A1W2PPK0
SLNNNFLQTLNQAWN	CUL3	96	Q13618
IQQALANRWLNENYT	HUNK	311	P57058
SQLWAFLNIKQVADQ	C1orf112	606	Q9NSG2
ISINASNNFNLNITW	ATRNL1	1146	Q5VV63
WTNAQNQSFSAILNA	CSF3R	566	Q99062
WNSQSSIDQKLANQI	ERVK-21	511	P61565
LSNNSDANLELINTW	SERPING1	251	P05155
SESQLELNWNNRFLN	IL2RG	166	P31785
LWNSQSSIDQKLANQ	HERVK_113	511	Q902F9
QKVDNAQAFLWLSQL	DNAH9	1796	Q9NYC9
QLGLTNAQVITWFQN	LBX1	161	P52954
WSQTLWINLNVQILQ	DNAH10	1281	Q8IVF4
AQTNLTLLQVNNWFI	PKNOX2	326	Q96KN3
LNANLLDSLWDTFQN	COL6A6	1276	A6NMZ7
QWSSAQSQLQSQLPQ	CPHXL	346	A0A1W2PPM1
TNASLLTKLQAQNQW	IL6	171	P05231
NLQNWLNTSNVTLEN	LRRC19	186	Q9H756
QNSIALSWQAPAFSN	EPHA6	456	Q9UF33
TGLTILQVNNWFINA	MEIS3P1	201	A6NDR6
SIQNVVNNRWLNSSF	MIGA1	486	Q8NAN2
RRFWNTLQSINQTDQ	SZT2	491	Q5T011
NLSLLQISNWFINAR	TGIF2LX	91	Q8IUE1
NNSAAQHLFIQTFWQ	RRP1B	86	Q14684
TELLQLNNNDWYSQR	NBR1	951	Q14596
AAQTNLTLLQVNNWF	PKNOX1	296	P55347
FKLTLQQQSSLDQWA	RFX2	571	P48378
ANRTILVDNNTWNNT	STT3A	536	P46977
QSENLWINRSLQYSA	PKHD1	2626	P08F94
LNLGRNFSVQWNQIF	SI	921	P14410
AAQNWILEILQNAAQ	URB1	1826	O60287
RNWADAQTQIQNIAA	SEC23A	501	Q15436
SLIAAQFNQNDWQAS	SPAG17	21	Q6Q759
SSLLEQLNEQFNWVS	CLU	356	P10909
QLNEQFNWVSRLANL	CLU	361	P10909
LQTWDTINLNSFFTQ	RNF213	541	Q63HN8
QVTQFWNLLDDLAQS	PIH1D2	11	Q8WWB5
NKWIQQNLQCLVLNS	ZYG11B	131	Q9C0D3
NSVLNQLNWAFSEFI	RNF123	1031	Q5XPI4
EAAIFNRWINNASLQ	STAB2	1006	Q8WWQ8
WNQFSVTALQLLQAN	VAT1	306	Q99536
LQWIELLTKQFNNSQ	USP34	2326	Q70CQ2
LLQFSTIQQNDWLRA	TMEM267	36	Q0VDI3
ANIQQQLARLDNESW	WWC3	246	Q9ULE0
QLNLSETQVKVWFQN	VAX1	136	Q5SQQ9
TQSLWLNNNVLNDLR	LRRC51	51	Q96E66