Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11	4.58e-11	11	139	6	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	2.89e-08	14	139	5	GO:0003964
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11	1.99e-07	37	139	6	GO:0016891
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25	1.99e-07	37	139	6	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25	2.35e-07	38	139	6	GO:0070001
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	2.83e-07	21	139	5	GO:0035613
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11	7.61e-07	46	139	6	GO:0016893
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	3.27e-06	5	139	3	GO:0030156
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	6.35e-06	38	139	5	GO:0034061
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11	1.87e-05	79	139	6	GO:0004521
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERVK-6 PDGFRA STK26 GRK6 CDK11A ERVK-7 ERVK-10 ITPKB STK3 PARP4 TRNT1 TESK2 ERVK-8 MAP3K11 TSSK3 ERVK-11 TSSK1B STK24 STK25	2.77e-05	938	139	19	GO:0016772
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11 CNOT1	4.71e-05	136	139	7	GO:0004540
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 ERVK-7 ERVK-10 PARP4 TRNT1 ERVK-8 ERVK-11	9.51e-05	152	139	7	GO:0016779
GeneOntologyMolecularFunction	protein homodimerization activity	ERVK-6 MASP1 PDGFRA STK26 MSTN TRNT1 CCDC88A RACK1 F11R PTPRO MAP3K11 KMT2A HSD17B4 RPE TBX1 STK25	1.79e-04	815	139	16	GO:0042803
GeneOntologyMolecularFunction	hexosaminidase activity	NAGLU CEMIP OGA	2.09e-04	17	139	3	GO:0015929
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11	3.82e-04	136	139	6	GO:0004519
GeneOntologyMolecularFunction	protein serine kinase activity	STK26 CDK11A STK3 TESK2 MAP3K11 TSSK3 TSSK1B STK24 STK25	1.01e-03	363	139	9	GO:0106310
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	STK26 GRK6 CDK11A STK3 TESK2 MAP3K11 TSSK3 TSSK1B STK24 STK25	1.15e-03	446	139	10	GO:0004674
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11 CNOT1	1.19e-03	231	139	7	GO:0004518
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2A	1.31e-03	8	139	2	GO:0140945
GeneOntologyMolecularFunction	hyalurononglucosaminidase activity	CEMIP OGA	1.68e-03	9	139	2	GO:0004415
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11	1.21e-10	13	136	6	GO:0015074
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11	7.19e-07	48	136	6	GO:0000731
GeneOntologyBiologicalProcess	DNA-templated DNA replication	ERVK-6 LRWD1 ERVK-7 ERVK-10 E2F8 CCNE2 NYNRIN ERVK-8 ERVK-11	2.84e-06	178	136	9	GO:0006261
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-6 ERVK-7 ERVK-10 PARP4 ERVK-8 ERVK-11	1.83e-05	83	136	6	GO:0006278
GeneOntologyCellularComponent	acrosomal vesicle	SPATA31A3 TCP11 SPATA31A7 FAM220A SPATA31A6 SPATA31A5 SPATA31A1 TSSK1B	6.55e-05	206	137	8	GO:0001669
GeneOntologyCellularComponent	FAR/SIN/STRIPAK complex	STK26 STK24 STK25	1.75e-04	17	137	3	GO:0090443
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	9.68e-07	12	127	4	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	9.68e-07	12	127	4	IPR027970
Domain	Znf_CHHC	HNRNPH1 HNRNPH2	1.37e-04	3	127	2	IPR012996
Domain	zf-RNPHF	HNRNPH1 HNRNPH2	1.37e-04	3	127	2	PF08080
Domain	-	COL12A1 CPNE5 PARP4 CACNA2D4 HMCN1	1.49e-04	74	127	5	3.40.50.410
Domain	S_TKc	PDGFRA STK26 GRK6 CDK11A STK3 MAP3K11 TSSK3 TSSK1B STK24 STK25	1.73e-04	359	127	10	SM00220
Domain	VWFA	COL12A1 CPNE5 PARP4 CACNA2D4 HMCN1	2.41e-04	82	127	5	PS50234
Domain	Protein_kinase_ATP_BS	PDGFRA STK26 GRK6 STK3 TESK2 MAP3K11 TSSK3 TSSK1B STK24 STK25	2.68e-04	379	127	10	IPR017441
Domain	VWA	COL12A1 CPNE5 PARP4 CACNA2D4 HMCN1	2.70e-04	84	127	5	SM00327
Domain	Pkinase	STK26 GRK6 CDK11A STK3 TESK2 MAP3K11 TSSK3 TSSK1B STK24 STK25	2.79e-04	381	127	10	PF00069
Domain	PROTEIN_KINASE_ATP	PDGFRA STK26 GRK6 CDK11A STK3 TESK2 MAP3K11 TSSK3 TSSK1B STK24 STK25	3.01e-04	459	127	11	PS00107
Domain	Ig-like_fold	COL12A1 PDGFRA DCC RIMBP3 IGSF10 IGKV1-5 F11R HMCN1 PTPRO CNTN5 RIMBP3C ADGRF5 RIMBP3B CD96	3.21e-04	706	127	14	IPR013783
Domain	Ig_I-set	PDGFRA DCC IGSF10 F11R HMCN1 CNTN5 ADGRF5	3.23e-04	190	127	7	IPR013098
Domain	I-set	PDGFRA DCC IGSF10 F11R HMCN1 CNTN5 ADGRF5	3.23e-04	190	127	7	PF07679
Domain	FN3	COL12A1 DCC RIMBP3 PTPRO CNTN5 RIMBP3C RIMBP3B	4.27e-04	199	127	7	PS50853
Domain	FYrich_C	KMT2C KMT2A	4.53e-04	5	127	2	IPR003889
Domain	FYrich_N	KMT2C KMT2A	4.53e-04	5	127	2	IPR003888
Domain	FYRC	KMT2C KMT2A	4.53e-04	5	127	2	SM00542
Domain	FYRN	KMT2C KMT2A	4.53e-04	5	127	2	SM00541
Domain	INTEGRASE	ERVK-6 NYNRIN	4.53e-04	5	127	2	PS50994
Domain	Integrase_cat-core	ERVK-6 NYNRIN	4.53e-04	5	127	2	IPR001584
Domain	FYRN	KMT2C KMT2A	4.53e-04	5	127	2	PF05964
Domain	FYRC	KMT2C KMT2A	4.53e-04	5	127	2	PF05965
Domain	FYRC	KMT2C KMT2A	4.53e-04	5	127	2	PS51543
Domain	FYRN	KMT2C KMT2A	4.53e-04	5	127	2	PS51542
Domain	Prot_kinase_dom	PDGFRA STK26 GRK6 CDK11A STK3 TESK2 MAP3K11 TSSK3 TSSK1B STK24 STK25	5.14e-04	489	127	11	IPR000719
Domain	PROTEIN_KINASE_DOM	PDGFRA STK26 GRK6 CDK11A STK3 TESK2 MAP3K11 TSSK3 TSSK1B STK24 STK25	5.49e-04	493	127	11	PS50011
Domain	FN3_dom	COL12A1 DCC RIMBP3 PTPRO CNTN5 RIMBP3C RIMBP3B	5.72e-04	209	127	7	IPR003961
Domain	VWF_A	COL12A1 CPNE5 PARP4 CACNA2D4 HMCN1	5.77e-04	99	127	5	IPR002035
Domain	-	COL12A1 PDGFRA DCC RIMBP3 IGSF10 F11R HMCN1 PTPRO CNTN5 RIMBP3C ADGRF5 RIMBP3B CD96	5.87e-04	663	127	13	2.60.40.10
Domain	PROTEIN_KINASE_ST	STK26 GRK6 CDK11A STK3 MAP3K11 TSSK3 TSSK1B STK24 STK25	8.33e-04	362	127	9	PS00108
Domain	IGc2	PDGFRA DCC IGSF10 F11R HMCN1 CNTN5 ADGRF5	1.14e-03	235	127	7	SM00408
Domain	Ig_sub2	PDGFRA DCC IGSF10 F11R HMCN1 CNTN5 ADGRF5	1.14e-03	235	127	7	IPR003598
Domain	Kinase-like_dom	PDGFRA STK26 GRK6 CDK11A STK3 TESK2 MAP3K11 TSSK3 TSSK1B STK24 STK25	1.19e-03	542	127	11	IPR011009
Domain	RNaseH-like_dom	ERVK-6 FAM200A PRPF8 NYNRIN	1.25e-03	69	127	4	IPR012337
Domain	FN3	COL12A1 DCC PTPRO CNTN5 RIMBP3C RIMBP3B	1.67e-03	185	127	6	SM00060
Domain	IGv	IGSF10 IGKV1-5 F11R HMCN1	1.71e-03	75	127	4	SM00406
Domain	SH3_9	RIMBP3 MAP3K11 RIMBP3C RIMBP3B	1.97e-03	78	127	4	PF14604
Domain	SH3_2	RIMBP3 MAP3K11 RIMBP3C RIMBP3B	2.82e-03	86	127	4	PF07653
Domain	SH3_2	RIMBP3 MAP3K11 RIMBP3C RIMBP3B	2.82e-03	86	127	4	IPR011511
Domain	Ser/Thr_kinase_AS	GRK6 CDK11A STK3 MAP3K11 TSSK3 TSSK1B STK24 STK25	3.08e-03	357	127	8	IPR008271
Domain	Post-SET_dom	KMT2C KMT2A	5.17e-03	16	127	2	IPR003616
Domain	PostSET	KMT2C KMT2A	5.17e-03	16	127	2	SM00508
Domain	AT_hook	KMT2C KMT2A	5.17e-03	16	127	2	PF02178
Domain	POST_SET	KMT2C KMT2A	5.17e-03	16	127	2	PS50868
Domain	IG_LIKE	PDGFRA DCC IGSF10 IGKV1-5 F11R HMCN1 CNTN5 ADGRF5 CD96	6.41e-03	491	127	9	PS50835
Domain	LH2	PKD1L2 LIPC	6.54e-03	18	127	2	SM00308
Domain	VWA	COL12A1 PARP4 CACNA2D4	6.55e-03	56	127	3	PF00092
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	6.10e-12	6	141	5	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	6.10e-12	6	141	5	25930072
Pubmed	STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development.	STK26 STK3 STK24 STK25	3.21e-08	9	141	4	34518307
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	4.07e-08	24	141	5	32212159
Pubmed	SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions.	STK26 STK24 STK25	6.52e-08	3	141	3	23889253
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25 ERVK-11	1.18e-07	94	141	7	21542922
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	2.60e-07	4	141	3	10469592
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	2.60e-07	4	141	3	19091768
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-18	6.48e-07	5	141	3	12629516
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	6.48e-07	5	141	3	17855024
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-18 ERVK-25 ERVK-11	7.58e-07	18	141	4	18664271
Pubmed	CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation.	STK26 STK24 STK25	2.26e-06	7	141	3	20332113
Pubmed	Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress.	STK26 STK24 STK25	2.26e-06	7	141	3	22291017
Pubmed	Signal transduction protein array analysis links LRRK2 to Ste20 kinases and PKC zeta that modulate neuronal plasticity.	STK3 STK24 STK25	7.67e-06	10	141	3	20949042
Pubmed	Association of MTHFR and PICALM polymorphisms with Alzheimer's disease.	PICALM MTHFR	1.63e-05	2	141	2	25359311
Pubmed	A novel chromosomal inversion at 11q23 in infant acute myeloid leukemia fuses MLL to CALM, a gene that encodes a clathrin assembly protein.	PICALM KMT2A	1.63e-05	2	141	2	12461747
Pubmed	STE20-type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies.	STK26 STK24	1.63e-05	2	141	2	37490000
Pubmed	Differences in degradation lead to asynchronous expression of cyclin E1 and cyclin E2 in cancer cells.	CCNE2 FBXW7	1.63e-05	2	141	2	23324394
Pubmed	Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways.	STK24 STK25	1.63e-05	2	141	2	19855390
Pubmed	GCKIII (Germinal Center Kinase III) Kinases STK24 and STK25 (Serine/Threonine Kinase 24 and 25) Inhibit Cavernoma Development.	STK24 STK25	1.63e-05	2	141	2	35130716
Pubmed	Expression Levels of Myostatin and Matrix Metalloproteinase 14 mRNAs in Uterine Leiomyoma are Correlated With Dysmenorrhea.	MSTN MMP14	1.63e-05	2	141	2	26138721
Pubmed	GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation.	TNRC6C CNOT1	1.63e-05	2	141	2	23463101
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	1.63e-05	2	141	2	11672541
Pubmed	Bioinformatics analysis identified MMP14 and COL12A1 as immune-related biomarkers associated with pancreatic adenocarcinoma prognosis.	COL12A1 MMP14	1.63e-05	2	141	2	34517516
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	2.30e-05	14	141	3	17662146
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	CDK11A TFIP11 PRPF8 SPATA31A6 KMT2C SCN9A CCAR1 KMT2A CNOT1 HYDIN	3.78e-05	497	141	10	36774506
Pubmed	Association of SET domain and myotubularin-related proteins modulates growth control.	SBF1 KMT2A	4.88e-05	3	141	2	9537414
Pubmed	Structural basis for the unique heterodimeric assembly between cerebral cavernous malformation 3 and germinal center kinase III.	STK26 STK25	4.88e-05	3	141	2	23665169
Pubmed	Long non-coding RNA CASC2 suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells through CASC2/miR-367/FBXW7 axis.	CASC2 FBXW7	4.88e-05	3	141	2	28716020
Pubmed	CEMIP promotes small cell lung cancer proliferation by activation of glutamine metabolism via FBXW7/c-Myc-dependent axis.	CEMIP FBXW7	4.88e-05	3	141	2	36746261
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2C KMT2A	4.88e-05	3	141	2	23932714
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-11	4.88e-05	3	141	2	9971820
Pubmed	MST1/2 regulates fibro/adipogenic progenitor fate decisions in skeletal muscle regeneration.	PDGFRA STK3	4.88e-05	3	141	2	38552635
Pubmed	Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants.	HOXA3 TBX1	4.88e-05	3	141	2	16696966
Pubmed	SCF(Fbxw7/hCdc4) targets cyclin E2 for ubiquitin-dependent proteolysis.	CCNE2 FBXW7	4.88e-05	3	141	2	19084516
Pubmed	Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues.	HNRNPH1 HNRNPH2	4.88e-05	3	141	2	14980514
Pubmed	Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.	HNRNPH1 HNRNPH2	4.88e-05	3	141	2	7499401
Pubmed	Uncommon somatic mutations in metastatic NUT midline carcinoma.	DCC KMT2C	4.88e-05	3	141	2	28967088
Pubmed	Mutational spectrum of F8 gene and prothrombotic gene variants in haemophilia A patients from Southern Italy.	F8 MTHFR	4.88e-05	3	141	2	18459951
Pubmed	Structural mechanism of CCM3 heterodimerization with GCKIII kinases.	STK26 STK24	4.88e-05	3	141	2	23541896
Pubmed	Plasma homocysteine, methylene tetrahydrofolate reductase C677T and factor II G20210A polymorphisms, factor VIII, and VWF in central retinal vein occlusion.	F8 MTHFR	4.88e-05	3	141	2	11673296
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-18	4.88e-05	3	141	2	10516026
Pubmed	Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription.	HNRNPH1 STK3	4.88e-05	3	141	2	20145135
Pubmed	Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.	SETX HNRNPH1	4.88e-05	3	141	2	29725819
Pubmed	Differential expression of MST4, STK25 and PDCD10 between benign prostatic hyperplasia and prostate cancer.	STK26 STK25	4.88e-05	3	141	2	25550858
Pubmed	CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization.	STK26 STK25	4.88e-05	3	141	2	21561863
Pubmed	Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes.	HSPA12A CNTN5	4.88e-05	3	141	2	17903304
Pubmed	hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization.	HNRNPH1 HNRNPH2	4.88e-05	3	141	2	10456323
Pubmed	Rack1 protects N-terminal phosphorylated c-Jun from Fbw7-mediated degradation.	RACK1 FBXW7	4.88e-05	3	141	2	21860413
Pubmed	Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.	HNRNPH1 HNRNPH2	4.88e-05	3	141	2	21068389
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SETX NAGLU SLC26A9 ICE1 AGPS CSMD2 PRPF8 HNRNPH1 IGSF10 KMT2C PARP4 CNOT1	4.89e-05	736	141	12	29676528
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	DCC IGSF10 F11R HMCN1 CNTN5 ADGRF5	5.43e-05	162	141	6	25826454
Pubmed	Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling.	DCC HOXA3 HOXB5	8.22e-05	21	141	3	18547144
Pubmed	Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.	HNRNPH1 HNRNPH2 CNOT1	9.49e-05	22	141	3	18377426
Pubmed	A novel member of the testis specific serine kinase family, tssk-3, expressed in the Leydig cells of sexually mature mice.	TSSK3 TSSK1B	9.74e-05	4	141	2	10781952
Pubmed	The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.	TNRC6C CNOT1	9.74e-05	4	141	2	23172285
Pubmed	Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli.	NEDD4L SCN9A	9.74e-05	4	141	2	27604420
Pubmed	Physical localization of eed: a region of mouse chromosome 7 required for gastrulation.	HIKESHI PICALM	9.74e-05	4	141	2	7558026
Pubmed	Prothrombotic polymorphisms in patients with Raynaud's phenomenon and migraine.	F8 MTHFR	9.74e-05	4	141	2	23238545
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2C KMT2A	9.74e-05	4	141	2	23129768
Pubmed	Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.	KMT2C KMT2A	9.74e-05	4	141	2	19703992
Pubmed	Release of STK24/25 suppression on MEKK3 signaling in endothelial cells confers cerebral cavernous malformation.	STK24 STK25	9.74e-05	4	141	2	36692953
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2C KMT2A	9.74e-05	4	141	2	24081332
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10	9.74e-05	4	141	2	7983737
Pubmed	YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta.	STK26 STK25	9.74e-05	4	141	2	15037601
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SETX STARD8 TTLL3 TFIP11 FCHO2 E2F8 KMT2C TRNT1 RACK1 ALDH1L2 RPE CNOT1 STK24 STK25	1.38e-04	1084	141	14	11544199
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	LRWD1 SETX PRPF8 PICALM HNRNPH1 PARP4 HSPA12A ENAH CNOT1 STK24	1.39e-04	582	141	10	20467437
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	1.62e-04	5	141	2	11401426
Pubmed	Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1.	APLP2 MAP3K11	1.62e-04	5	141	2	12917434
Pubmed	Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.	XIRP1 ENAH	1.62e-04	5	141	2	16631741
Pubmed	Physical activity modulates effects of some genetic polymorphisms affecting cardiovascular risk in men aged over 40 years.	LIPC MTHFR	1.62e-04	5	141	2	14650352
Pubmed	Genetic variation and neuroimaging measures in Alzheimer disease.	PICALM CNTN5	1.62e-04	5	141	2	20558387
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ICE1 PRPF8 PARP4 HEATR6 SBF1 CNOT1	1.82e-04	202	141	6	33005030
Pubmed	Rebalancing gene haploinsufficiency in vivo by targeting chromatin.	KMT2C KMT2A TBX1	1.98e-04	28	141	3	27256596
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	MASP1 HMGCL ICE1 STK3 KMT2C NDUFA12 DNAJC28 RACK1 SBF1 PTPRO TMEM44 NGEF OGA STK25	2.01e-04	1124	141	14	21900206
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SETX NEDD4L PDGFRA LARP1B E2F8 ITPKB STK3 CCDC88A SBF1 TESK2 KMT2A TSSK1B	2.12e-04	861	141	12	36931259
Pubmed	Netrin-1 is a chemorepellent for oligodendrocyte precursor cells in the embryonic spinal cord.	PDGFRA DCC	2.42e-04	6	141	2	12736344
Pubmed	Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testis.	TSSK3 TSSK1B	2.42e-04	6	141	2	20729278
Pubmed	CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations.	STK24 STK25	2.42e-04	6	141	2	17657516
Pubmed	Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis.	PDGFRA CIDEC	2.42e-04	6	141	2	32958928
Pubmed	Comparison of thrombophilic gene mutations among patients experiencing recurrent miscarriage and deep vein thrombosis.	F8 MTHFR	2.42e-04	6	141	2	18803625
Pubmed	Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organisms.	PDGFRA HOXA3	2.42e-04	6	141	2	20071345
Pubmed	The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1.	STK26 STK3	2.42e-04	6	141	2	15688006
Pubmed	Common polymorphisms and cardiovascular factors in patients with myocardial infarction of Costa Rica.	F8 MTHFR	2.42e-04	6	141	2	18457169
Pubmed	MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases.	STK26 STK25	2.42e-04	6	141	2	21423148
Pubmed	Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting.	STK24 STK25	2.42e-04	6	141	2	34156031
Pubmed	Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.	PRPF8 HNRNPH1 HNRNPH2 STK24	3.07e-04	79	141	4	14729942
Pubmed	Hierarchical CRMP2 posttranslational modifications control NaV1.7 function.	NEDD4L SCN9A	3.38e-04	7	141	2	27940916
Pubmed	Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.	KMT2C KMT2A	3.38e-04	7	141	2	26324722
Pubmed	RHO binding to FAM65A regulates Golgi reorientation during cell migration.	STK26 STK24	3.38e-04	7	141	2	27807006
Pubmed	Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development.	HOXA3 TBX1	3.38e-04	7	141	2	16284121
Pubmed	A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins.	HNRNPH1 HNRNPH2	3.38e-04	7	141	2	31704785
Pubmed	Aortic arch and pharyngeal phenotype in the absence of BMP-dependent neural crest in the mouse.	HOXA3 TBX1	3.38e-04	7	141	2	12464426
Pubmed	Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers.	KMT2C KMT2A	3.38e-04	7	141	2	36598580
Pubmed	Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs.	HOXA3 TBX1	3.38e-04	7	141	2	15581866
Pubmed	Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.	HNRNPH1 HNRNPH2	3.38e-04	7	141	2	25846207
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	XIRP1 FAM220A KMT2C NYNRIN ENAH SCN9A	3.91e-04	233	141	6	37704626
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	LPCAT1 STK26 CDK11A STK3 CCNE2 KMT2A STK24 STK25	3.99e-04	432	141	8	23455922
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2C KMT2A	4.50e-04	8	141	2	22266653
Pubmed	The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution.	HOXA3 HOXB5	4.50e-04	8	141	2	1688181
Cytoband	22q11.21	RTL10 RIMBP3 RIMBP3C RIMBP3B TBX1	2.60e-05	111	142	5	22q11.21
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	2.63e-04	8	142	2	chr9q12
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PDGFRA DCC IGSF10 HMCN1 CNTN5 ADGRF5	8.49e-05	161	81	6	593
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STK26 STK24 STK25	9.35e-05	20	81	3	1371
GeneFamily	Immunoglobulin like domain containing	DCC F11R CNTN5 ADGRF5 CD96	1.75e-03	193	81	5	594
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 FRMPD2 DCC CEMIP SPHKAP CNTN5 ADGRF5	1.20e-06	179	134	7	8766a5a066091879f521acfc612abf563ff78808
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA12 PKD1L2 DCC HMCN1 SCN9A HYDIN	1.45e-06	184	134	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA12 PKD1L2 DCC HMCN1 SCN9A HYDIN	1.45e-06	184	134	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA12 PKD1L2 DCC HMCN1 SCN9A HYDIN	1.45e-06	184	134	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	moderate-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LINC00473 COL12A1 PDGFRA HSPA12A ALDH1L2 ADGRF5 MMP14	1.73e-06	189	134	7	22a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCell	B_cells-Plasmablasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LARP1B DCC CPNE5 NXPE3 IGKV1-5 ALDH1L2 FBXW7	1.73e-06	189	134	7	87cb7b6ba9fd57100d68e6eaeecd1ac6ab22d1c6
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	F8 ITPKB MMRN1 HMCN1 SPAAR TMEM44 ADGRF5	1.99e-06	193	134	7	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPNE5 SFMBT2 NXPE3 IGKV1-5 CCDC88A ALDH1L2 FBXW7	2.13e-06	195	134	7	bb30ac112f8c42d113fa83a9b662e40c0685bb1e
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA12 FRMPD2 E2F8 CNTN5 NGEF CFAP74 HYDIN	2.28e-06	197	134	7	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F8 CEMIP MMRN1 SPHKAP ADGRF5 HYDIN	7.57e-06	155	134	6	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA12 DCC HMCN1 SPHKAP HYDIN	9.08e-06	160	134	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA12 DCC HMCN1 SPHKAP HYDIN	9.08e-06	160	134	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	STK26 CPNE5 NGEF KLHL34 OGA FBXW7	9.41e-06	161	134	6	ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CATSPERD FRMPD2 CASC2 HSPA12A CFAP74 HYDIN	1.08e-05	165	134	6	731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DCC CPNE5 NXPE3 CCDC88A RIMBP3C FBXW7	1.20e-05	168	134	6	f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	STARD8 F8 SPAAR TMEM44 ADGRF5 GASK1A	1.24e-05	169	134	6	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	COVID-19-kidney-Plasma\|kidney / Disease (COVID-19 only), tissue and cell type	DCC SFMBT2 NXPE3 CCDC88A ALDH1L2 FBXW7	1.33e-05	171	134	6	a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 FRMPD2 DCC SPHKAP CNTN5 ADGRF5	1.46e-05	174	134	6	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DCC CPNE5 NXPE3 CCDC88A RIMBP3C FBXW7	1.51e-05	175	134	6	6a093c74a6f3daeff07759d6eec542fc5c709149
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK26 F8 ITPKB HEATR6 SPHKAP ENAH	1.66e-05	178	134	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F8 NXPE3 HOXB5 HSPA12A TMEM44 ADGRF5	1.72e-05	179	134	6	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNFSF18 SLC26A9 F8 CEMIP MMRN1 TBX1	1.72e-05	179	134	6	1c0c0647a111f691dae55f4ed8c51006059ce020
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNFSF18 SLC26A9 CEMIP MMRN1 ADGRF5 TBX1	1.72e-05	179	134	6	dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F8 IGSF10 HSPA12A NYNRIN KMT2A ADGRF5	1.77e-05	180	134	6	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F8 IGSF10 HSPA12A NYNRIN KMT2A ADGRF5	1.77e-05	180	134	6	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCC CPNE5 SFMBT2 NXPE3 ALDH1L2 FBXW7	1.83e-05	181	134	6	6cdee2f56bc633b387b4dbbd78c624edbd712c24
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCC CPNE5 SFMBT2 NXPE3 ALDH1L2 FBXW7	1.83e-05	181	134	6	b75b8b025257bccfe661fd0f92ab284b2a9c12ee
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MASP1 COL12A1 PDGFRA MSTN HOXB5 HMCN1	1.83e-05	181	134	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	LINC00473 CACUL1 NEDD4L ITPKB HEATR6 TESK2	1.83e-05	181	134	6	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC26A9 F8 CEMIP HMCN1 TBX1 KLHL17	1.89e-05	182	134	6	f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETX PPFIA4 STK26 FCHO2 CCDC88A KMT2A	2.01e-05	184	134	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LARP1B DCC CPNE5 NXPE3 ALDH1L2 FBXW7	2.07e-05	185	134	6	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	droplet-Heart-nan-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP2 HOXB5 F11R CIDEC TMEM44 ADGRF5	2.07e-05	185	134	6	a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|lung / Disease (COVID-19 only), tissue and cell type	LARP1B DCC CPNE5 SFMBT2 NXPE3 FBXW7	2.13e-05	186	134	6	66676d9395172de5707e204826a1c9f73b448cca
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP2 FCHO2 ITPKB F11R HMCN1 ADGRF5	2.13e-05	186	134	6	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	IPF-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	CDCA3 DCC CPNE5 E2F8 IGKV1-5 CCDC88A	2.13e-05	186	134	6	f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell	droplet-Heart-nan-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PICALM HOXB5 F11R CIDEC TMEM44 ADGRF5	2.26e-05	188	134	6	9dfa2e0b73640459cdf88277291e3ab9c33e0217
ToppCell	hematopoetic_progenitors-CD34+_HSC\|World / Lineage and Cell class	HOXA3 MMRN1 IGSF10 HOXB5 NYNRIN SCN9A	2.33e-05	189	134	6	51ff31c9cf5eff98ad01c0455dc4ae4908713575
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL12A1 PDGFRA CSMD2 HMCN1 ENAH MMP14	2.55e-05	192	134	6	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FRMPD2 CASC2 WDPCP IGSF10 CFAP74 HYDIN	2.62e-05	193	134	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	facs-MAT-Fat-3m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMRN1 F11R SPAAR TMEM44 ADGRF5 TBX1	2.62e-05	193	134	6	b32533afeff1905e188becaa09079e9699722e4b
ToppCell	facs-MAT-Fat-3m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMRN1 F11R SPAAR TMEM44 ADGRF5 TBX1	2.62e-05	193	134	6	2ff573ba2c74583ed1cb071a3bbc01bb71117e5f
ToppCell	facs-MAT-Fat-3m-Endothelial-endothelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMRN1 F11R SPAAR TMEM44 ADGRF5 TBX1	2.62e-05	193	134	6	e164f6403a8b541ced08a6feec915d2e855036ea
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LPCAT1 NEDD4L CATSPERD PEBP4 ADGRF5 HYDIN	2.62e-05	193	134	6	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL12A1 PDGFRA IGSF10 HSPA12A MMP14 GASK1A	2.78e-05	195	134	6	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	LPCAT1 NEDD4L SLC26A9 PEBP4 LIPC ADGRF5	2.78e-05	195	134	6	b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 APLP2 F8 MMRN1 ADGRF5 TBX1	2.78e-05	195	134	6	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DCC CPNE5 SFMBT2 NXPE3 ALDH1L2 FBXW7	2.86e-05	196	134	6	fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell	Influenza-Influenza_Severe-Lymphocyte-B-Plasmablast\|Influenza_Severe / Disease, condition lineage and cell class	CDCA3 PDGFRA CPNE5 IGSF10 ALDH1L2 CCNE2	2.94e-05	197	134	6	9108edafbf5744ed65f556bcbbf819a9b71176a9
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	COL12A1 PDGFRA CSMD2 CEMIP HMCN1 ENAH	2.94e-05	197	134	6	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	distal-3-Epithelial-Proximal_Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CATSPERD ABCA12 FRMPD2 NGEF CFAP74 HYDIN	2.94e-05	197	134	6	15b4d1203943ce90a7083178d4a4284d9b323071
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LPCAT1 APLP2 SSR2 PEBP4 ADGRF5 HSD17B4	3.03e-05	198	134	6	85215015bb86ada0e871c413a4ecdc903a3785ca
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 PDGFRA PICALM HOXB5 HMCN1 MMP14	3.03e-05	198	134	6	a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LPCAT1 NEDD4L SLC26A9 DCC PEBP4 ADGRF5	3.03e-05	198	134	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DCC CPNE5 SFMBT2 NXPE3 ALDH1L2 FBXW7	3.03e-05	198	134	6	567fcf882c8612356946240843525b786f3c8dbe
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LPCAT1 APLP2 SSR2 PEBP4 ADGRF5 HSD17B4	3.03e-05	198	134	6	38349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Mesothelial-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	LINC00473 COL12A1 PDGFRA TM6SF2 ALDH1L2 GASK1A	3.11e-05	199	134	6	60a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCell	tumor_Lung-Epithelial_cells\|tumor_Lung / Location, Cell class and cell subclass	LPCAT1 NEDD4L APLP2 F11R ENAH ADGRF5	3.11e-05	199	134	6	56b3f6c8b561d60780d91daf6b44a9dcf616e599
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL12A1 SETX KMT2C HMCN1 KMT2A ADGRF5	3.20e-05	200	134	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	LPCAT1 SSR2 PEBP4 RACK1 ADGRF5 HSD17B4	3.20e-05	200	134	6	e6fea85df357731aad343e412672b5828403029f
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ST6GALNAC6 CEMIP SBF1 STK24 ANKS3	6.57e-05	140	134	5	af9efcbaeeae69fcdac4a15fa244728b65915564
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	CATSPERD DCC CSMD2 PEBP4 CNTN5	8.01e-05	146	134	5	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	10x5'-blood-Lymphocytic_B_plasma-Plasma_cells\|blood / Manually curated celltypes from each tissue	DCC CPNE5 IGKV1-5 KHDC1L ALDH1L2	8.27e-05	147	134	5	58089378fac1743ce99dc4f1bd7b5253a927f050
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 PDGFRA PPFIA4 MSTN CNTN5	9.10e-05	150	134	5	8645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCell	10x5'-blood-Lymphocytic_B_plasma\|blood / Manually curated celltypes from each tissue	DCC CPNE5 IGKV1-5 KHDC1L ALDH1L2	9.10e-05	150	134	5	6bab0a8bf78ed7de9e1b67ede7496488f80f4863
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MASP1 STARD8 ICE1 TNRC6C SCN9A	9.69e-05	152	134	5	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDCA3 GRK6 FAM220A CEMIP CD96	9.99e-05	153	134	5	c4dcdcaa672929c1da870e9fb8ada1bb030ad12f
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SETX STK26 ICE1 RACK1 OGA	1.06e-04	155	134	5	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SETX APLP2 ICE1 RACK1 OGA	1.20e-04	159	134	5	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FCHO2 SFMBT2 CACNA2D4 ALDH1L2 GASK1A	1.23e-04	160	134	5	709ce00699ca05346287868ea55a1affae0859a8
ToppCell	Globus_pallidus-Neuronal-Excitatory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	STK26 CPNE5 NGEF KLHL34 OGA	1.23e-04	160	134	5	f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	F11R HMCN1 SPAAR ADGRF5 TBX1	1.27e-04	161	134	5	a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	F11R HMCN1 SPAAR ADGRF5 TBX1	1.31e-04	162	134	5	0bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	F11R HMCN1 SPAAR ADGRF5 TBX1	1.31e-04	162	134	5	5799a602ef8d83925907e8e34532428be7330228
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TCP11 HOXA3 IGSF10 NYNRIN TMEM44	1.31e-04	162	134	5	233011408f022647932c81ebab78f9813e3c6833
ToppCell	IIF-Other-HSPC\|IIF / Disease, Lineage and Cell Type	HOXA3 MMRN1 IGSF10 NYNRIN SCN9A	1.34e-04	163	134	5	1e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCell	normal_Lung-Epithelial_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	LPCAT1 NEDD4L APLP2 PEBP4 ADGRF5	1.38e-04	164	134	5	fa2dae15b38cb8f9642dbf00549beec8ee19e9bb
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	E2F8 RIMBP3 PTPRO SYTL5 ALG13	1.42e-04	165	134	5	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	CEMIP HOXA3 MMRN1 NYNRIN SCN9A	1.42e-04	165	134	5	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	Healthy_donor-HSPC\|World / disease group, cell group and cell class (v2)	CATSPERD PPFIA4 IGSF10 HOXB5 NYNRIN	1.51e-04	167	134	5	70630ebdfee8171d625811844f8a7c94736d101e
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|368C / Donor, Lineage, Cell class and subclass (all cells)	F8 MMRN1 TMEM44 SCN9A TBX1	1.55e-04	168	134	5	a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	F8 MMRN1 TMEM44 SCN9A TBX1	1.55e-04	168	134	5	dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD2 DCC TESK2 SPHKAP ADGRF5	1.64e-04	170	134	5	985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SETX STK26 ICE1 RACK1 OGA	1.68e-04	171	134	5	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LPCAT1 SFMBT2 CACNA2D4 CD96 BORA	1.73e-04	172	134	5	1aecc98a3eadabae0f1f328091a9733d916017ec
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARP1B CPNE5 PICALM LIPC ALG13	1.77e-04	173	134	5	0a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCP11 TM6SF2 SFMBT2 MMRN1 TBX1	1.77e-04	173	134	5	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 DCC SPHKAP CNTN5 ADGRF5	1.82e-04	174	134	5	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDCA3 TM6SF2 CSMD2 PEBP4 IGSF10	1.87e-04	175	134	5	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDCA3 TM6SF2 CSMD2 PEBP4 IGSF10	1.87e-04	175	134	5	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	Control-B_cells-Plasma_cells\|Control / group, cell type (main and fine annotations)	DCC CPNE5 NXPE3 ALDH1L2 FBXW7	1.87e-04	175	134	5	fb23858cfce71509cafbe0d9728e678012ff2962
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F8 MMRN1 MAP3K11 ADGRF5 TBX1	1.87e-04	175	134	5	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DCC CPNE5 CASC2 E2F8 ALDH1L2	1.87e-04	175	134	5	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDCA3 TM6SF2 CSMD2 PEBP4 IGSF10	1.87e-04	175	134	5	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDCA3 TM6SF2 CSMD2 PEBP4 IGSF10	1.87e-04	175	134	5	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LPCAT1 STK26 ICE1 RACK1 OGA	1.97e-04	177	134	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MMRN1 TMEM44 SPHKAP SCN9A TBX1	1.97e-04	177	134	5	c274fbdc141855ff4581d437d4997c64cc193278
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 DCC SPHKAP CNTN5 ADGRF5	1.97e-04	177	134	5	f902600c639087664316b3cf30cab243bc3d1c5c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LPCAT1 STK26 ICE1 RACK1 OGA	1.97e-04	177	134	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MMRN1 TMEM44 SPHKAP SCN9A TBX1	1.97e-04	177	134	5	f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
Disease	cerebral cavernous malformation (implicated_via_orthology)	STK26 STK24 STK25	1.17e-05	11	124	3	DOID:0060669 (implicated_via_orthology)
Disease	NF-kappa-B essential modulator measurement	STK3 STK24	5.24e-05	3	124	2	EFO_0010597
Disease	blood osmolality measurement	NEDD4L ABCA12 PKD1L2 CEMIP	1.06e-04	58	124	4	EFO_0007967
Disease	unipolar depression, depressive symptom measurement	DCC CNTN5 KMT2A	1.75e-04	26	124	3	EFO_0003761, EFO_0007006
Disease	Colorectal Carcinoma	STARD8 CACUL1 TTLL3 ABCA12 FRMPD2 DCC KMT2C MTHFR CCAR1 TBX1 FBXW7	1.90e-04	702	124	11	C0009402
Disease	prostate-specific antigen measurement, disease progression measurement	SPHKAP NGEF	3.63e-04	7	124	2	EFO_0008336, EFO_0020660
Disease	pulse pressure measurement, diastolic blood pressure, systolic blood pressure, hypertension	HOXA3 STK3 STK24	4.30e-04	35	124	3	EFO_0000537, EFO_0005763, EFO_0006335, EFO_0006336
Disease	free cholesterol in small HDL measurement	TM6SF2 LIPC NYNRIN	4.30e-04	35	124	3	EFO_0022270
Disease	2-hydroxystearate measurement	STK3 STK24	6.19e-04	9	124	2	EFO_0021059
Disease	Thrombophilia	F8 MTHFR	6.19e-04	9	124	2	C0398623
Disease	Congenital Heart Defects	HOXA3 MTHFR TBX1	8.46e-04	44	124	3	C0018798
Disease	factor VIII deficiency (is_implicated_in)	F8 MTHFR	9.40e-04	11	124	2	DOID:12134 (is_implicated_in)
Disease	rheumatoid arthritis (implicated_via_orthology)	KMT2C MMP14	1.12e-03	12	124	2	DOID:7148 (implicated_via_orthology)
Disease	Spina Bifida	PDGFRA MTHFR	1.12e-03	12	124	2	C0080178
Disease	Status Dysraphicus	PDGFRA MTHFR	1.12e-03	12	124	2	C0038219
Disease	Rachischisis	PDGFRA MTHFR	1.12e-03	12	124	2	C0266508
Disease	tetralogy of Fallot (is_implicated_in)	MTHFR TBX1	1.33e-03	13	124	2	DOID:6419 (is_implicated_in)
Disease	imidazole lactate measurement	SLC38A7 CNOT1	1.33e-03	13	124	2	EFO_0800004
Disease	free cholesterol measurement	IRF2BP1 TM6SF2 LIPC NYNRIN	1.34e-03	113	124	4	EFO_0008591
Disease	Childhood Acute Lymphoblastic Leukemia	MTHFR KMT2A FBXW7	1.38e-03	52	124	3	C0023452
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	PICALM HNRNPH1 FBXW7	1.46e-03	53	124	3	C1961099
Disease	response to lithium ion	COL12A1 CSMD2 CNTN5	1.71e-03	56	124	3	GO_0010226
Disease	chenodeoxycholate measurement	DCC HMCN1	1.77e-03	15	124	2	EFO_0010471
Disease	periprosthetic osteolysis, disease progression measurement	SFMBT2 CEMIP	1.77e-03	15	124	2	EFO_0008336, EFO_0009761
Disease	lipid metabolism disorder (implicated_via_orthology)	MTHFR HSD17B4	1.77e-03	15	124	2	DOID:3146 (implicated_via_orthology)
Disease	Acute Myeloid Leukemia, M1	PICALM KMT2C ENAH KMT2A	1.95e-03	125	124	4	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	PICALM KMT2C ENAH KMT2A	1.95e-03	125	124	4	C1879321
Disease	triacylglycerol 50:5 measurement	TM6SF2 CACNA2D4	2.02e-03	16	124	2	EFO_0010412
Disease	esterified cholesterol measurement	IRF2BP1 TM6SF2 LIPC NYNRIN	2.12e-03	128	124	4	EFO_0008589
Disease	Alzheimer disease, psychotic symptoms	TNRC6C PICALM	2.29e-03	17	124	2	EFO_0005940, MONDO_0004975
Disease	Parkinson disease	COL12A1 NAGLU ITPKB MMRN1 HEATR6 NGEF	2.41e-03	321	124	6	MONDO_0005180
Disease	squamous cell carcinoma (is_implicated_in)	KMT2C MTHFR	2.56e-03	18	124	2	DOID:1749 (is_implicated_in)
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	IRF2BP1 TM6SF2 LIPC NYNRIN HSD17B4	2.61e-03	224	124	5	EFO_0004574, EFO_0008317
Disease	cholesteryl ester measurement, very low density lipoprotein cholesterol measurement	IRF2BP1 TM6SF2 LIPC NYNRIN HSD17B4	2.66e-03	225	124	5	EFO_0008317, EFO_0010351
Disease	total lipids in small VLDL	TM6SF2 LIPC HSD17B4	2.85e-03	67	124	3	EFO_0022148
Disease	Phenyllactate (PLA) measurement	SLC38A7 CNOT1	2.86e-03	19	124	2	EFO_0021662
Disease	event free survival time, urinary bladder cancer	DCC SFMBT2	2.86e-03	19	124	2	EFO_0000482, MONDO_0001187
Disease	anorectal malformation	CSMD2 KLHL17	2.86e-03	19	124	2	MONDO_0019938
Disease	DiGeorge syndrome (implicated_via_orthology)	HOXA3 TBX1	2.86e-03	19	124	2	DOID:11198 (implicated_via_orthology)
Disease	diacylglycerol 38:5 measurement	TM6SF2 LIPC	2.86e-03	19	124	2	EFO_0020067
Disease	ascending aortic diameter	MASP1 SLC27A6 HMCN1 HYDIN	2.93e-03	140	124	4	EFO_0021787
Disease	Precursor B-cell lymphoblastic leukemia	PDGFRA KMT2A	3.49e-03	21	124	2	C1292769
Disease	Deep Vein Thrombosis	F8 MTHFR	3.49e-03	21	124	2	C0149871
Disease	Infiltrating duct carcinoma of female breast	GRK6 TESK2	3.49e-03	21	124	2	C3165106
Disease	Venous Thrombosis	F8 MTHFR	3.49e-03	21	124	2	C0042487
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	DCC TM6SF2	3.49e-03	21	124	2	OBA_2045104
Disease	alkaline phosphatase measurement	CACUL1 NEDD4L TCP11 LARP1B FCHO2 TM6SF2 ITPKB LIPC NYNRIN CNOT1 KLHL17	3.74e-03	1015	124	11	EFO_0004533
Disease	age at onset, Myopia	CDCA3 FRMPD2 PKD1L2 HYDIN	3.75e-03	150	124	4	EFO_0004847, HP_0000545
Disease	otitis media (implicated_via_orthology)	NAGLU TBX1	3.83e-03	22	124	2	DOID:10754 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPVPQQFSMSNILWK	ARSD	556	P51689
NLKPVTQVMSVPAWN	ALG13	541	Q9NP73
SQPQNWTTMIKEFGG	CATSPERD	626	Q86XM0
PLIPNGKVVGSDFMW	CSMD2	3016	Q7Z408
KAGTAGWNEPQMVFP	ACTL8	16	Q9H568
MAQFGGQKNPPWATQ	CCAR1	1	Q8IX12
KDIINMPAGPVIWAF	ABCA12	786	Q86UK0
KVPGAWTEINGQMVT	ALDH1L2	251	Q3SY69
ADAPSWMNKPVVDGN	FAM220A	41	Q7Z4H9
SLPPAIWNAEQMKAF	FCHO2	721	Q0JRZ9
PWQQMDKASPGVAYT	RTL10	26	Q7L3V2
DWMVPFVNVVKSTSP	CCNE2	326	O96020
PKPRQDCNAVSTFWM	CEMIP	661	Q8WUJ3
WMKDPFAFQNPESII	FAM200A	451	Q8TCP9
VFPQVNVTKMGSWGH	NAGLU	256	P54802
MPPWNQTEFPSKQVF	CDCA3	136	Q99618
EWVQMAPTLFSKFIP	CACUL1	296	Q86Y37
GNPVPTITWMKVNGY	CNTN5	326	O94779
PTDKIDAALFWMPNG	MMP14	411	P50281
GWVTQIATTPQFPDM	RACK1	16	P63244
PWETSQMPESQVKGS	RIMBP3B	706	A6NNM3
PWETSQMPESQVKGS	RIMBP3C	706	A6NJZ7
PQPWALGQVVTKTMV	LRWD1	606	Q9UFC0
KNTFWDVDGSMVPPE	NDUFA12	71	Q9UI09
MHVNIQTGKWEPDPT	APLP2	61	Q06481
FLPVKWMAPESIFDN	PDGFRA	856	P16234
GKPVPTVNWMKNGDV	DCC	356	P43146
MSLVFGKFVPVNWEP	LY6G5C	36	Q5SRR4
QPTVVDPVSFMFWKD	MTHFR	571	P42898
SNGKWPQIMIFPEGT	LPCAT1	196	Q8NF37
PEEQVWSKKAPMGTA	KLHL34	501	Q8N239
FCLQPVMKSVPTNGW	KMT2C	416	Q8NEZ4
LNSPTVAKQIFPWMK	HOXA3	146	O43365
SWTIPEDGNSQKTMP	MMRN1	26	Q13201
RKGMPFAQWDGPTVV	PPFIA4	821	O75335
MVQSSPPISGEDNKW	CCDC88A	1016	Q3V6T2
VEMDWVLKHTGPNSP	HNRNPH2	91	P55795
IKNMWAAFPPDVGGN	MYLPF	136	Q96A32
ITSWMEPIVKFPGAV	PEBP4	71	Q96S96
LGNPMTPTEKKQWNH	DNAJC28	281	Q9NX36
MAAVQVVGSWPSVQP	HEATR6	1	Q6AI08
EPATRFQWKVLPQGM	HERVK_113	151	P63132
FQWKVLPQGMLNSPT	HERVK_113	156	P63132
WQMVAALKSQPAQPV	LIPC	101	P11150
VWQVLKENGPMASDP	F8	156	P00451
ITVPAIWKQPAKQFM	HSPA12A	201	O43301
VEMDWVLKHTGPNSP	HNRNPH1	91	P31943
FFMPATVAPWQQDKA	PARP4	746	Q9UKK3
EPATRFQWKVLPQGM	ERVK-7	151	P63135
FQWKVLPQGMLNSPT	ERVK-7	156	P63135
EPATRFQWKVLPQGM	ERVK-6	151	Q9BXR3
FQWKVLPQGMLNSPT	ERVK-6	156	Q9BXR3
TSIMFWGVPKDPAEQ	PKD1L2	1566	Q7Z442
GTPSPIIMWYKDNVQ	HMCN1	1386	Q96RW7
WIVDQAAAKMQGAPP	SBF1	516	O95248
QGPLPETRNDFWKMV	PTPRO	1011	Q16827
TAAPEGQTPQIFPWM	HOXB5	166	P09067
EPATRFQWKVLPQGM	ERVK-18	151	Q9QC07
FQWKVLPQGMLNSPT	ERVK-18	156	Q9QC07
MQWIAPQVVSQKGEG	WDPCP	441	O95876
KSLQMDPVFWESQGG	GASK1A	526	Q9UFP1
SPSEMFIPANVVLKW	HIKESHI	166	Q53FT3
LNCSATGEPKPQIMW	IGSF10	1961	Q6WRI0
TVKWVDVPRNMPGTF	HYDIN	3751	Q4G0P3
NWEKNAPVDVGFMVS	ICE1	2071	Q9Y2F5
SPKAGAWESVAPMNI	KLHL17	551	Q6TDP4
GSQGEPWTPTANLKM	E2F8	51	A0AVK6
TMNVFWEPVPGKVRK	COL12A1	1581	Q99715
QAVPPSNMKQSWLIF	LINC00473	101	A8K010
PLQPMPVAWAFVQKT	CACNA2D4	36	Q7Z3S7
MNPALPWKLEGSNST	CASC2	81	Q6XLA1
APEGWREQPQKTSMN	FRMPD2	406	Q68DX3
PVYPGQTLQTEMWKE	HSD17B4	566	P51659
TWIKEPVDNGSLPMT	BORA	446	Q6PGQ7
TSVQPPTGLQEWLKM	FBXW7	226	Q969H0
SMFPTWPAKSEQQRV	CDK11A	721	Q9UQ88
NGRPAQKGTTPWIAM	MASP1	451	P48740
QVASVKWPNSVMAPG	MIDEAS	91	Q6PJG2
PPADSKGWQASLQAM	ANKS3	601	Q6ZW76
QTRVTVVGPPMAKQW	KHDC1L	66	Q5JSQ8
FWEPNKVSSNSGMLP	KMT2A	1776	Q03164
WLPGAKCDIQMTQSP	IGKV1-5	16	P01602
PWERTNTMNGSKSPV	ENAH	496	Q8N8S7
KFATGSVPIPWQNEM	GRK6	501	P43250
EAPMTIWVADQNKPV	CFAP74	891	Q9C0B2
QTKDMGAQAPWVPEA	MAP3K11	831	Q16584
MKNTLNPVWQTFSIP	CPNE5	221	Q9HCH3
KCPLVGSSVPWAFMQ	IRF2BP1	551	Q8IU81
MENWPTPSELVNTGF	LARP1B	1	Q659C4
GDPPAQEWFMVQTKS	NYNRIN	6	Q9P2P1
WFKDGIVMPTNPKST	F11R	166	Q9Y624
QRLWQKMANNPGTPF	SYTL5	701	Q8TDW5
PRGPKVAQWAMETAV	SPAAR	6	A0A1B0GVQ0
AWKRGSEFLMTPNVP	SPHKAP	961	Q2M3C7
MPNVHSKTENSWGEP	TNRC6C	806	Q9HCJ0
KEMQQWSIPPFPVSG	TRNT1	376	Q96Q11
QFPVPWEKCPLTMNS	SLC6A16	216	Q9GZN6
FPWEFVRMGLTQPKG	SPATA5L1	486	Q9BVQ7
TPVSPVVSQWKDMIG	SLC26A9	321	Q7LBE3
SWIPFMQEKYTKPNG	OGA	796	O60502
NIKMPVNSSGPDWVT	NXPE3	286	Q969Y0
PWETSQMPESQVKGS	RIMBP3	706	Q9UFD9
TTNPKPFWNMGENSK	SPATA31A6	376	Q5VVP1
IKRNTFVGTPFWMAP	STK24	186	Q9Y6E0
FVGTPFWMAPEVIKQ	STK24	191	Q9Y6E0
GTPFWMAPEVIQQSA	STK26	181	Q9P289
VQPGNSRVWQGTMEK	ITPKB	501	P27987
IETTSFVSPKWVPQM	HMGCL	71	P35914
FVSPKWVPQMGDHTE	HMGCL	76	P35914
MNPGTGIWQSIDVKT	MSTN	196	O14793
TTNPKPFWNMGENSK	SPATA31A7	376	Q8IWB4
GWFPSSMTEEILNPK	NGEF	661	Q8N5V2
IFMTMNNPPDWTKNV	SCN9A	141	Q15858
MSSPQLPAFLWDKGT	SMIM42	1	A0A5F9ZH02
GSKVWGQLMDPIVAF	SETX	301	Q7Z333
PETVFIFWGPPSKMQ	ST6GALNAC6	176	Q969X2
NSMQQPEVKTWGGVV	SLC38A7	266	Q9NVC3
KRNTFVGTPFWMAPE	STK25	171	O00506
VGTPFWMAPEVIKQS	STK25	176	O00506
AAERFKGWMSVPGPQ	STARD8	831	Q92502
SVWSPSMKLNLVPGE	ADGRF5	651	Q8IZF2
SGMGLPTFKEWIQNT	AGPS	121	O00116
VFMVLQKGQKWQPPS	CIDEC	106	Q96AQ7
PTGFLAQPMKQAWAT	CNOT1	1591	A5YKK6
WLAQQAAKAMAPTSP	MRPL9	251	Q9BYD2
EPATRFQWKVLPQGM	ERVK-25	151	P63136
FQWKVLPQGMLNSPT	ERVK-25	156	P63136
KVAPTTAWNAATMAP	PICALM	581	Q13492
GNWFPGSKPLIQQAM	PRPF8	1716	Q6P2Q9
TTNPKPFWNMGENSK	SPATA31A3	376	Q5VYP0
KWLTQAAGDLTMSPP	TCP11	246	Q8WWU5
PEDFGIVSGMLNVKW	SSR2	66	P43308
AKRNTVIGTPFWMAP	STK3	176	Q13188
MALSPVPGNKVWNIS	CD96	356	P40200
TTNPKPFWNMGENSK	SPATA31A1	376	Q5TZJ5
TTNPKPFWNMGENSK	SPATA31A5	376	Q5VU36
PKMLWQQQKGVSFPT	TSSK3	216	Q96PN8
KFGPLPSKWQMASSE	TNFSF18	61	Q9UNG2
EPATRFQWKVLPQGM	ERVK-10	151	P10266
FQWKVLPQGMLNSPT	ERVK-10	156	P10266
VGWCTQNNKVLMPPD	SFMBT2	131	Q5VUG0
EPATRFQWKVLPQGM	ERVK-8	151	P63133
FQWKVLPQGMLNSPT	ERVK-8	156	P63133
EPATRFQWKVLPQGM	ERVK-11	151	Q9UQG0
FQWKVLPQGMLNSPT	ERVK-11	156	Q9UQG0
HEIWRGQMSKPSQSP	TMEM44	216	Q2T9K0
APNAWSTIIVPGMKD	TTLL3	416	Q9Y4R7
WMQPKARGSPSVAIN	TSSK1B	271	Q9BXA7
HPDSPAKGAQWMKQI	TBX1	196	O43435
VPCWAGMKVFSQPRA	TM6SF2	181	Q9BZW4
NISVWGMKDSVPQGV	SLC27A6	176	Q9Y2P4
PEQWVKPMAVAGANQ	RPE	76	Q96AT9
SEKLAVVGSPFWMAP	TESK2	211	Q96S53
AEAQSCTWMFKPQPV	XIRP1	621	Q702N8
PGSWEAFMVKNIVPK	TFIP11	601	Q9UBB9
QHKVTQSFLPPGWEM	NEDD4L	491	Q96PU5