Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	long-chain fatty acid-CoA ligase activity	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	1.59e-08	15	114	5	GO:0004467
GeneOntologyMolecularFunction	arachidonate-CoA ligase activity	ACSL6 ACSL1 ACSBG2 ACSL5	3.22e-07	11	114	4	GO:0047676
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	3.32e-07	26	114	5	GO:0015645
GeneOntologyMolecularFunction	CoA-ligase activity	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	4.05e-07	27	114	5	GO:0016405
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	8.38e-07	31	114	5	GO:0016878
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	3.53e-06	41	114	5	GO:0016877
GeneOntologyMolecularFunction	ligase activity	ACSL6 MDM2 ACSL1 ACSBG1 ACSBG2 QRSL1 ACSL5	6.36e-05	174	114	7	GO:0016874
GeneOntologyMolecularFunction	phosphorylase kinase activity	PHKA1 PHKA2	1.92e-04	4	114	2	GO:0004689
GeneOntologyMolecularFunction	oleoyl-CoA ligase activity	ACSL1 ACSL5	1.92e-04	4	114	2	GO:0090434
GeneOntologyMolecularFunction	rRNA (cytosine-C5-)-methyltransferase activity	NSUN4 NOP2	1.92e-04	4	114	2	GO:0009383
GeneOntologyMolecularFunction	exogenous lipid antigen binding	CD1B CD1C	3.19e-04	5	114	2	GO:0030884
GeneOntologyMolecularFunction	endogenous lipid antigen binding	CD1B CD1C	3.19e-04	5	114	2	GO:0030883
GeneOntologyMolecularFunction	rRNA (cytosine) methyltransferase activity	NSUN4 NOP2	4.77e-04	6	114	2	GO:0016434
GeneOntologyMolecularFunction	lipid antigen binding	CD1B CD1C	4.77e-04	6	114	2	GO:0030882
GeneOntologyMolecularFunction	ATP-dependent activity	ACSL6 ABCC3 WAPL HSPH1 CHD4 ACSL1 ACSBG1 NAV2 ACSBG2 ASCC3 ACSL5	7.80e-04	614	114	11	GO:0140657
GeneOntologyMolecularFunction	C-methyltransferase activity	NSUN4 NOP2	8.85e-04	8	114	2	GO:0008169
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	INPPL1 TULP1 ZFYVE28 ARAP3 DENND1B OSBPL5	9.93e-04	199	114	6	GO:1901981
GeneOntologyMolecularFunction	phospholipid binding	INPPL1 TULP1 NUP35 ZFYVE28 SYT16 ARAP3 DENND1B SYT14 OSBPL5 MCF2L	1.18e-03	548	114	10	GO:0005543
GeneOntologyMolecularFunction	very long-chain fatty acid-CoA ligase activity	ACSBG1 ACSBG2	1.41e-03	10	114	2	GO:0031957
GeneOntologyMolecularFunction	lipopeptide binding	CD1B CD1C	1.41e-03	10	114	2	GO:0071723
GeneOntologyMolecularFunction	cytoskeletal protein binding	NPHS1 LIMA1 ANK1 SYNM INPPL1 SPTB HSPH1 TULP1 SETD2 DST GAS2L2 ANKRD1 SYNE2 PKD2 MICAL3	1.46e-03	1099	114	15	GO:0008092
GeneOntologyMolecularFunction	phosphatidylinositol binding	INPPL1 TULP1 ZFYVE28 ARAP3 DENND1B OSBPL5 MCF2L	2.26e-03	316	114	7	GO:0035091
GeneOntologyMolecularFunction	cytidine deaminase activity	APOBEC3G APOBEC3A	2.42e-03	13	114	2	GO:0004126
GeneOntologyBiologicalProcess	long-chain fatty-acyl-CoA biosynthetic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	4.51e-08	19	111	5	GO:0035338
GeneOntologyBiologicalProcess	positive regulation of long-chain fatty acid import across plasma membrane	ACSL6 ACSL1 ACSL5	1.52e-07	3	111	3	GO:0010747
GeneOntologyBiologicalProcess	long-chain fatty-acyl-CoA metabolic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	3.03e-07	27	111	5	GO:0035336
GeneOntologyBiologicalProcess	fatty-acyl-CoA biosynthetic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	3.03e-07	27	111	5	GO:0046949
GeneOntologyBiologicalProcess	positive regulation of long-chain fatty acid import into cell	ACSL6 ACSL1 ACSL5	6.04e-07	4	111	3	GO:0140214
GeneOntologyBiologicalProcess	fatty-acyl-CoA metabolic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	2.99e-06	42	111	5	GO:0035337
GeneOntologyBiologicalProcess	regulation of long-chain fatty acid import across plasma membrane	ACSL6 ACSL1 ACSL5	5.23e-06	7	111	3	GO:0010746
GeneOntologyBiologicalProcess	acyl-CoA biosynthetic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	6.51e-06	49	111	5	GO:0071616
GeneOntologyBiologicalProcess	thioester biosynthetic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	6.51e-06	49	111	5	GO:0035384
GeneOntologyBiologicalProcess	fatty acid derivative biosynthetic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	8.76e-06	52	111	5	GO:1901570
GeneOntologyBiologicalProcess	regulation of long-chain fatty acid import into cell	ACSL6 ACSL1 ACSL5	1.24e-05	9	111	3	GO:0140212
GeneOntologyBiologicalProcess	positive regulation of fatty acid transport	ACSL6 ACSL1 PLA2R1 ACSL5	1.70e-05	29	111	4	GO:2000193
GeneOntologyBiologicalProcess	nucleoside bisphosphate biosynthetic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	1.93e-05	61	111	5	GO:0033866
GeneOntologyBiologicalProcess	ribonucleoside bisphosphate biosynthetic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	1.93e-05	61	111	5	GO:0034030
GeneOntologyBiologicalProcess	purine nucleoside bisphosphate biosynthetic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	1.93e-05	61	111	5	GO:0034033
GeneOntologyBiologicalProcess	long-chain fatty acid import across plasma membrane	ACSL6 ACSL1 ACSL5	3.22e-05	12	111	3	GO:0015911
GeneOntologyBiologicalProcess	long-chain fatty acid metabolic process	ACSL6 CYP4Z1 ACSL1 ACSBG1 ACSBG2 ACSL5	5.66e-05	124	111	6	GO:0001676
GeneOntologyBiologicalProcess	regulation of fatty acid transport	ACSL6 ACSL1 PLA2R1 ACSL5	7.59e-05	42	111	4	GO:2000191
GeneOntologyBiologicalProcess	fatty acid derivative metabolic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	8.09e-05	82	111	5	GO:1901568
GeneOntologyBiologicalProcess	long-chain fatty acid import into cell	ACSL6 ACSL1 ACSL5	1.62e-04	20	111	3	GO:0044539
GeneOntologyBiologicalProcess	fatty acid transmembrane transport	ACSL6 ACSL1 ACSL5	2.17e-04	22	111	3	GO:1902001
GeneOntologyBiologicalProcess	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	CD1B CD1C	2.84e-04	5	111	2	GO:0048006
GeneOntologyBiologicalProcess	acyl-CoA metabolic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	3.09e-04	109	111	5	GO:0006637
GeneOntologyBiologicalProcess	thioester metabolic process	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	3.09e-04	109	111	5	GO:0035383
GeneOntologyBiologicalProcess	lipid import into cell	ACSL6 ACSL1 ACSL5	3.20e-04	25	111	3	GO:0140354
GeneOntologyBiologicalProcess	positive regulation of organic acid transport	ACSL6 ACSL1 PLA2R1 ACSL5	3.71e-04	63	111	4	GO:0032892
GeneOntologyBiologicalProcess	regulation of signal transduction by p53 class mediator	HIPK4 MDM2 PLA2R1 ANKRD1 NOP2	4.63e-04	119	111	5	GO:1901796
GeneOntologyBiologicalProcess	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	CD1B CD1C	5.92e-04	7	111	2	GO:0048007
GeneOntologyBiologicalProcess	antigen processing and presentation of lipid antigen via MHC class Ib	CD1B CD1C	5.92e-04	7	111	2	GO:0048003
GeneOntologyCellularComponent	extracellular matrix	NPHS1 MXRA5 OLFML2B MMP27 DST HMCN2 NAV2 NGLY1 LGR6 MMP2 MMP8 DMP1 MUC2	6.02e-05	656	114	13	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	NPHS1 MXRA5 OLFML2B MMP27 DST HMCN2 NAV2 NGLY1 LGR6 MMP2 MMP8 DMP1 MUC2	6.21e-05	658	114	13	GO:0030312
GeneOntologyCellularComponent	phosphorylase kinase complex	PHKA1 PHKA2	2.92e-04	5	114	2	GO:0005964
Domain	AMP-binding_CS	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	4.61e-07	26	114	5	IPR020845
Domain	AMP_BINDING	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	6.81e-07	28	114	5	PS00455
Domain	AMP-binding	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	9.79e-07	30	114	5	PF00501
Domain	AMP-dep_Synth/Lig	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	9.79e-07	30	114	5	IPR000873
Domain	CH	SPTB DST GAS2L2 SYNE2 NAV2 MICAL3	2.79e-06	65	114	6	SM00033
Domain	CH	SPTB DST GAS2L2 SYNE2 NAV2 MICAL3	4.32e-06	70	114	6	PF00307
Domain	-	SPTB DST GAS2L2 SYNE2 NAV2 MICAL3	4.70e-06	71	114	6	1.10.418.10
Domain	CH	SPTB DST GAS2L2 SYNE2 NAV2 MICAL3	5.53e-06	73	114	6	PS50021
Domain	CH-domain	SPTB DST GAS2L2 SYNE2 NAV2 MICAL3	6.47e-06	75	114	6	IPR001715
Domain	Spectrin	SPTB DST SYNE2 MCF2L	1.07e-05	23	114	4	PF00435
Domain	Spectrin_repeat	SPTB DST SYNE2 MCF2L	2.78e-05	29	114	4	IPR002017
Domain	SPEC	SPTB DST SYNE2 MCF2L	4.15e-05	32	114	4	SM00150
Domain	Spectrin/alpha-actinin	SPTB DST SYNE2 MCF2L	4.15e-05	32	114	4	IPR018159
Domain	Pept_M10A_Zn_BS	MMP27 MMP2 MMP8	9.55e-05	15	114	3	IPR021158
Domain	Glyco_hydro_15/PHK	PHKA1 PHKA2	1.10e-04	3	114	2	IPR011613
Domain	PHK_A/B_su	PHKA1 PHKA2	1.10e-04	3	114	2	IPR008734
Domain	Glyco_hydro_15	PHKA1 PHKA2	1.10e-04	3	114	2	PF00723
Domain	Hemopexin_CS	MMP27 MMP2 MMP8	1.41e-04	17	114	3	IPR018486
Domain	PG_binding_1	MMP27 MMP2 MMP8	2.34e-04	20	114	3	PF01471
Domain	Peptidoglycan-bd-like	MMP27 MMP2 MMP8	2.34e-04	20	114	3	IPR002477
Domain	Hemopexin-like_dom	MMP27 MMP2 MMP8	3.59e-04	23	114	3	IPR000585
Domain	Hemopexin-like_repeat	MMP27 MMP2 MMP8	3.59e-04	23	114	3	IPR018487
Domain	HEMOPEXIN	MMP27 MMP2 MMP8	3.59e-04	23	114	3	PS00024
Domain	ACTININ_2	SPTB DST SYNE2	3.59e-04	23	114	3	PS00020
Domain	-	MMP27 MMP2 MMP8	3.59e-04	23	114	3	2.110.10.10
Domain	HEMOPEXIN_2	MMP27 MMP2 MMP8	3.59e-04	23	114	3	PS51642
Domain	ACTININ_1	SPTB DST SYNE2	3.59e-04	23	114	3	PS00019
Domain	HX	MMP27 MMP2 MMP8	3.59e-04	23	114	3	SM00120
Domain	Actinin_actin-bd_CS	SPTB DST SYNE2	3.59e-04	23	114	3	IPR001589
Domain	M10A_MMP	MMP27 MMP2 MMP8	3.59e-04	23	114	3	IPR033739
Domain	Hemopexin	MMP27 MMP2 MMP8	3.59e-04	23	114	3	PF00045
Domain	Pept_M10A	MMP27 MMP2 MMP8	3.59e-04	23	114	3	IPR021190
Domain	PKD_2	PKD1L2 PKD2	3.65e-04	5	114	2	IPR003915
Domain	Peptidase_M10	MMP27 MMP2 MMP8	4.08e-04	24	114	3	PF00413
Domain	GAR	DST GAS2L2	5.45e-04	6	114	2	PS51460
Domain	NOL1_NOP2_SUN	NSUN4 NOP2	5.45e-04	6	114	2	PS01153
Domain	GAS2	DST GAS2L2	5.45e-04	6	114	2	PF02187
Domain	RCMT	NSUN4 NOP2	5.45e-04	6	114	2	IPR023267
Domain	-	DST GAS2L2	5.45e-04	6	114	2	3.30.920.20
Domain	MHC_I_3	CD1B CD1C	5.45e-04	6	114	2	PF16497
Domain	GAS_dom	DST GAS2L2	5.45e-04	6	114	2	IPR003108
Domain	GAS2	DST GAS2L2	5.45e-04	6	114	2	SM00243
Domain	Peptidase_Metallo	MMP27 MMP2 MMP8	7.21e-04	29	114	3	IPR006026
Domain	ZnMc	MMP27 MMP2 MMP8	7.21e-04	29	114	3	SM00235
Domain	SAM_MT_RSMB_NOP	NSUN4 NOP2	7.60e-04	7	114	2	PS51686
Domain	6hp_glycosidase	PHKA1 PHKA2	1.01e-03	8	114	2	IPR012341
Domain	MeTrfase_RsmB/NOP2	NSUN4 NOP2	1.01e-03	8	114	2	IPR001678
Domain	-	PHKA1 PHKA2	1.01e-03	8	114	2	1.50.10.10
Domain	Methyltr_RsmB-F	NSUN4 NOP2	1.01e-03	8	114	2	PF01189
Domain	PKD_channel	PKD1L2 PKD2	1.96e-03	11	114	2	PF08016
Domain	PKD1_2_channel	PKD1L2 PKD2	1.96e-03	11	114	2	IPR013122
Domain	CYSTEINE_SWITCH	MMP27 MMP2 MMP8	1.99e-03	41	114	3	PS00546
Domain	SAM	INPPL1 LCP2 ARAP3 EPHA8	2.07e-03	88	114	4	SM00454
Domain	Pept_M10_metallopeptidase	MMP27 MMP2 MMP8	2.29e-03	43	114	3	IPR001818
Domain	SAM_2	INPPL1 LCP2 ARAP3	2.29e-03	43	114	3	PF07647
Domain	APOBEC_N	APOBEC3G APOBEC3A	2.34e-03	12	114	2	PF08210
Domain	APOBEC_N	APOBEC3G APOBEC3A	2.34e-03	12	114	2	IPR013158
Domain	SAM_DOMAIN	INPPL1 LCP2 ARAP3 EPHA8	2.74e-03	95	114	4	PS50105
Domain	6-hairpin_glycosidase-like	PHKA1 PHKA2	2.76e-03	13	114	2	IPR008928
Domain	-	PLA2R1 MMP2	2.76e-03	13	114	2	2.10.10.10
Domain	SAM	INPPL1 LCP2 ARAP3 EPHA8	2.95e-03	97	114	4	IPR001660
Domain	ZINC_PROTEASE	MMP27 MMP2 MMP8 ENPEP	3.06e-03	98	114	4	PS00142
Domain	FN_type2_col-bd	PLA2R1 MMP2	3.20e-03	14	114	2	IPR000562
Domain	FN2_2	PLA2R1 MMP2	3.20e-03	14	114	2	PS51092
Domain	FN2_1	PLA2R1 MMP2	3.20e-03	14	114	2	PS00023
Domain	APOBEC/CMP_deaminase_Zn-bd	APOBEC3G APOBEC3A	3.20e-03	14	114	2	IPR016192
Domain	fn2	PLA2R1 MMP2	3.20e-03	14	114	2	PF00040
Domain	FN2	PLA2R1 MMP2	3.20e-03	14	114	2	SM00059
Domain	-	INPPL1 LCP2 ARAP3 EPHA8	4.06e-03	106	114	4	1.10.150.50
Domain	CYT_DCMP_DEAMINASES_1	APOBEC3G APOBEC3A	4.73e-03	17	114	2	PS00903
Domain	CMP_dCMP_Zn-bd	APOBEC3G APOBEC3A	4.73e-03	17	114	2	IPR002125
Domain	Cytidine_deaminase-like	APOBEC3G APOBEC3A	4.73e-03	17	114	2	IPR016193
Domain	Pept_M10A_stromelysin-type	MMP27 MMP8	5.30e-03	18	114	2	IPR016293
Domain	SAM/pointed	INPPL1 LCP2 ARAP3 EPHA8	5.75e-03	117	114	4	IPR013761
Pathway	KEGG_MEDICUS_REFERENCE_BETA_OXIDATION_ACYL_COA_SYNTHESIS	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	4.01e-09	11	89	5	M47626
Pathway	WP_FATTY_ACID_TRANSPORTERS	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	7.19e-08	18	89	5	M42570
Pathway	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	2.17e-07	22	89	5	MM15451
Pathway	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	3.46e-07	24	89	5	M1016
Pathway	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	1.58e-06	32	89	5	MM15446
Pathway	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	3.33e-06	37	89	5	M729
Pathway	WP_PPAR_SIGNALING	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	6.36e-05	67	89	5	M39553
Pathway	WP_PPAR_SIGNALING_PATHWAY	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	9.59e-05	73	89	5	MM15995
Pathway	WP_FATTY_ACID_BIOSYNTHESIS	ACSL6 ACSL1 ACSL5	3.43e-04	22	89	3	M39440
Pathway	WP_FATTY_ACID_BIOSYNTHESIS	ACSL6 ACSL1 ACSL5	3.93e-04	23	89	3	MM15885
Pubmed	Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway.	ACSL6 ACSL1 ACSBG1 ACSL5	5.86e-10	5	116	4	24269233
Pubmed	Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family.	ACSL6 ACSL1 ACSL5	3.60e-07	5	116	3	15292367
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PLXNA3 ABCC3 INPPL1 APBB3 DLL1 DST ARAP3 MTMR14 OSBPL5 NAV2 MICAL3 TANC1 ZNF324B MCF2L NOTCH2 SDHA	8.57e-07	1105	116	16	35748872
Pubmed	Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart.	ACSL6 ACSL1 ACSL5	1.25e-06	7	116	3	17197235
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	WAPL SYNM SPTB HSPH1 APBB3 CHD4 YWHAG ZNF7 WDR3 DST YLPM1 NECAB3 ZNF350 MLST8 SDHA LRRFIP1 DNMT1	1.30e-06	1285	116	17	35914814
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	WAPL TUT7 CHD4 NUP35 WDR3 SETD2 ARID2 YLPM1 ASCC3 NOP2	2.35e-06	440	116	10	34244565
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	LIMA1 HIPK4 INPPL1 PAK6 YWHAG PPM1H DST DENND1B SYNE2 NAV2 TANC1 NOTCH2 DNMT1	6.32e-06	861	116	13	36931259
Pubmed	Phospho-tyrosine dependent protein-protein interaction network.	SPTB APBB3 MAGEC3 LCP2 STAT2 ARL6IP4 ARAP3 MLST8 LRRFIP1	1.01e-05	410	116	9	25814554
Pubmed	The multiphosphorylation domain of the phosphorylase kinase alpha M and alpha L subunits is a hotspot of differential mRNA processing and of molecular evolution.	PHKA1 PHKA2	1.10e-05	2	116	2	8226841
Pubmed	Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens.	CD1B CD1C	1.10e-05	2	116	2	10899914
Pubmed	Mutational characteristics of ANK1 and SPTB genes in hereditary spherocytosis.	ANK1 SPTB	1.10e-05	2	116	2	26830532
Pubmed	Identification and molecular characterization of acyl-CoA synthetase in human erythrocytes and erythroid precursors.	ACSL6 ACSL1	1.10e-05	2	116	2	10548543
Pubmed	The second member of the human and murine bubblegum family is a testis- and brainstem-specific acyl-CoA synthetase.	ACSBG1 ACSBG2	1.10e-05	2	116	2	16371355
Pubmed	Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues.	ANK1 SPTB	1.10e-05	2	116	2	11427698
Pubmed	Association Study between the Polymorphisms of Matrix Metalloproteinase (MMP) Genes and Idiopathic Recurrent Pregnancy Loss.	MMP27 MMP8	1.10e-05	2	116	2	31067818
Pubmed	X-linked liver glycogenosis type II (XLG II) is caused by mutations in PHKA2, the gene encoding the liver alpha subunit of phosphorylase kinase.	PHKA1 PHKA2	1.10e-05	2	116	2	8733133
Pubmed	Ankyrin binds to two distinct cytoplasmic domains of Na,K-ATPase alpha subunit.	ANK1 SPTB	1.10e-05	2	116	2	8159688
Pubmed	Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism.	DLL1 NOTCH2	1.10e-05	2	116	2	14660750
Pubmed	MDM2 is a novel E3 ligase for HIV-1 Vif.	APOBEC3G MDM2	1.10e-05	2	116	2	19128510
Pubmed	[Plasma matrix metalloproteinases-2 and -9 levels are elevated in patients with acute coronary syndrome and coronary chronic total occlusion].	MMP2 MMP8	1.10e-05	2	116	2	19460733
Pubmed	[Clinical characteristics and genetic analysis of hereditary spherocytosis caused by mutations of ANK1 and SPTB genes].	ANK1 SPTB	1.10e-05	2	116	2	31014431
Pubmed	cDNA cloning of a liver isoform of the phosphorylase kinase alpha subunit and mapping of the gene to Xp22.2-p22.1, the region of human X-linked liver glycogenosis.	PHKA1 PHKA2	1.10e-05	2	116	2	1372435
Pubmed	Association of single nucleotide polymorphisms in promoter of matrix metalloproteinase-2, 8 genes with bladder cancer risk in Northern India.	MMP2 MMP8	1.10e-05	2	116	2	21784671
Pubmed	Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains.	ACSL6 ACSL1	1.10e-05	2	116	2	16834775
Pubmed	Structural insight into an ankyrin-sensitive lipid-binding site of erythroid beta-spectrin.	ANK1 SPTB	1.10e-05	2	116	2	17520478
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	PLXNA3 ABCC3 MBTPS1 TUT7 HSPH1 YWHAG NUP35 PLA2R1 EDEM2 PKD2 NGLY1 MMP2 NOTCH2 LRRFIP1 DNMT1	1.15e-05	1201	116	15	35696571
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	WAPL HSPH1 CHD4 PKD1L2 DLL1 DST SYNE2 MMP2	1.32e-05	322	116	8	26514267
Pubmed	Association of matrix metalloproteinase gene polymorphisms with refractive error in Amish and Ashkenazi families.	MMP27 MMP2 MMP8	1.96e-05	16	116	3	20484597
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	LIMA1 INPPL1 PAK6 STAT2 DST NAV2 ELMOD3 TANC1 NOTCH2 LRRFIP1	2.07e-05	565	116	10	25468996
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	LIMA1 SYNM SPTB ACSL1 PTPRB DST MICAL3 LRRFIP1	2.93e-05	360	116	8	33111431
Pubmed	Restoring multidrug resistance-associated protein 3 attenuates cell proliferation in the polycystic kidney.	ABCC3 PKD2	3.30e-05	3	116	2	25143454
Pubmed	Dynamic regulation of CD45 lateral mobility by the spectrin-ankyrin cytoskeleton of T cells.	SPTB ANKRD1	3.30e-05	3	116	2	20164196
Pubmed	Matrix metalloproteinase levels in the differentiation of parapneumonic pleural effusions.	MMP2 MMP8	3.30e-05	3	116	2	20453486
Pubmed	Direct measurement of antigen binding properties of CD1 proteins using fluorescent lipid probes.	CD1B CD1C	3.30e-05	3	116	2	14551186
Pubmed	Inhibition of CD1 antigen presentation by human cytomegalovirus.	CD1B CD1C	3.30e-05	3	116	2	18287231
Pubmed	CD1a-, b-, and c-restricted TCRs recognize both self and foreign antigens.	CD1B CD1C	3.30e-05	3	116	2	16272286
Pubmed	Association of long-chain acyl-coenzyme A synthetase 5 expression in human breast cancer by estrogen receptor status and its clinical significance.	ACSL1 ACSL5	3.30e-05	3	116	2	28498416
Pubmed	Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.	DLL1 NOTCH2	3.30e-05	3	116	2	11823422
Pubmed	Regulatory variants of APOBEC3 genes potentially associate with COVID-19 severity in populations with African ancestry.	APOBEC3G APOBEC3A	3.30e-05	3	116	2	38105291
Pubmed	Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress.	MBTPS1 CREB3L1	3.30e-05	3	116	2	16417584
Pubmed	Prognostic significance of overexpressed matrix metalloproteinase-2, mouse-double minute: 2 homolog and epidermal growth factor receptor in non-small cell lung cancer.	MDM2 MMP2	3.30e-05	3	116	2	27273943
Pubmed	Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion.	PKD2 MMP2	3.30e-05	3	116	2	26507660
Pubmed	CD1a, CD1b, and CD1c in immunity against mycobacteria.	CD1B CD1C	3.30e-05	3	116	2	23468110
Pubmed	Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c.	CD1B CD1C	3.30e-05	3	116	2	2447586
Pubmed	p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS.	MBTPS1 CREB3L1	3.30e-05	3	116	2	37178686
Pubmed	Spectrin's E2/E3 ubiquitin conjugating/ligating activity is diminished in sickle cells.	ANK1 SPTB	3.30e-05	3	116	2	15929114
Pubmed	Targeting APOBEC3A to the viral nucleoprotein complex confers antiviral activity.	APOBEC3G APOBEC3A	3.30e-05	3	116	2	17727729
Pubmed	Changing patterns in cytoskeletal mRNA expression and protein synthesis during murine erythropoiesis in vivo.	ANK1 SPTB	3.30e-05	3	116	2	1385865
Pubmed	Notch signaling confers antigen-presenting cell functions on mast cells.	DLL1 NOTCH2	3.30e-05	3	116	2	19130928
Pubmed	Inherited hemolytic disease in mice: a review and update.	ANK1 SPTB	3.30e-05	3	116	2	6763106
Pubmed	HIV-1 viral infectivity factor interacts with TP53 to induce G2 cell cycle arrest and positively regulate viral replication.	APOBEC3G MDM2	3.30e-05	3	116	2	21071676
Pubmed	Animal models for human group 1 CD1 protein function.	CD1B CD1C	3.30e-05	3	116	2	33384157
Pubmed	[Human Papillomavirus Carcinogenesis Mediated by APOBEC Mutagenesis].	APOBEC3G APOBEC3A	3.30e-05	3	116	2	30606934
Pubmed	Glucoamylase-like domains in the alpha- and beta-subunits of phosphorylase kinase.	PHKA1 PHKA2	3.30e-05	3	116	2	12876330
Pubmed	Mapping the binding sites of human erythrocyte ankyrin for the anion exchanger and spectrin.	ANK1 SPTB	3.30e-05	3	116	2	2141335
Pubmed	A clinical and experimental study of adult hereditary spherocytosis in the Chinese population.	ANK1 SPTB	3.30e-05	3	116	2	32133777
Pubmed	Separate pathways for antigen presentation by CD1 molecules.	CD1B CD1C	3.30e-05	3	116	2	10626896
Pubmed	The 14-3-3/SLP76 protein-protein interaction in T-cell receptor signalling: a structural and biophysical characterization.	LCP2 YWHAG	3.30e-05	3	116	2	33159816
Pubmed	The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness.	APOBEC3G APOBEC3A	3.30e-05	3	116	2	36100631
Pubmed	Upregulation and atypical expression of the CD1 molecules on monocytes in sickle cell disease.	CD1B CD1C	3.30e-05	3	116	2	15556687
Pubmed	Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions.	APOBEC3G APOBEC3A	3.30e-05	3	116	2	22272271
Pubmed	Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells.	DLL1 NOTCH2	3.30e-05	3	116	2	15976178
Pubmed	Dysregulated CD1 profile in myeloid dendritic cells in CVID is normalized by IVIg treatment.	CD1B CD1C	3.30e-05	3	116	2	23766460
Pubmed	A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.	DLL1 PKD2 NOTCH2	3.37e-05	19	116	3	22675211
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SPTB CHD4 MDM2 DST MTMR14 ANKRD1 SYNE2 MMP2 NOTCH2	4.56e-05	497	116	9	23414517
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	WAPL ANK1 HSPH1 LCP2 PTPRB ARID2 NAV2 MICAL3 ASCC3	4.56e-05	497	116	9	36774506
Pubmed	Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition.	ANKRD1 MMP2 NOTCH2	4.60e-05	21	116	3	17303760
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	NSUN4 TUT7 ATG14 CHD4 ARL6IP4 WDR3 ARID2 ASCC3 NOP2 LRRFIP1 DNMT1	4.90e-05	759	116	11	35915203
Pubmed	Functional interactions between matrix metalloproteinases and glycosaminoglycans.	MMP27 MMP2 MMP8	5.32e-05	22	116	3	23421805
Pubmed	Matrix metalloproteinases.	MMP27 MMP2 MMP8	5.32e-05	22	116	3	10419448
Pubmed	Primary Cilia Deficiency Induces Intracranial Aneurysm.	PKD2 MMP2	6.59e-05	4	116	2	28800037
Pubmed	Gingival crevicular fluid levels of MMP-8, MMP-9, TIMP-2, and MPO decrease after periodontal therapy.	MMP2 MMP8	6.59e-05	4	116	2	19995403
Pubmed	Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes.	DLL1 NOTCH2	6.59e-05	4	116	2	22390640
Pubmed	Synaptotagmin gene content of the sequenced genomes.	SYT16 SYT14	6.59e-05	4	116	2	15238157
Pubmed	Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex.	TCF19 CHD4	6.59e-05	4	116	2	29042441
Pubmed	Antigen presentation by CD1 and MHC-encoded class I-like molecules.	CD1B CD1C	6.59e-05	4	116	2	8729450
Pubmed	The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes.	ANK1 SPTB	6.59e-05	4	116	2	379653
Pubmed	Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.	DLL1 NOTCH2	6.59e-05	4	116	2	28319044
Pubmed	Isolation of cDNA clones for the catalytic gamma subunit of mouse muscle phosphorylase kinase: expression of mRNA in normal and mutant Phk mice.	PHKA1 PHKA2	6.59e-05	4	116	2	3472241
Pubmed	Lipid presentation by human CD1 molecules and the diverse T cell populations that respond to them.	CD1B CD1C	6.59e-05	4	116	2	24556395
Pubmed	Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane.	DLL1 NOTCH2	6.59e-05	4	116	2	9244302
Pubmed	Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans.	SYT16 SYT14	6.59e-05	4	116	2	12801916
Pubmed	Clinical manifestation and phenotypic analysis of novel gene mutation in 28 Chinese children with hereditary spherocytosis.	ANK1 SPTB	6.59e-05	4	116	2	33620149
Pubmed	Distribution of matrix metalloproteinases MMP-1, MMP-2, MMP-8 and tissue inhibitor of matrix metalloproteinases-2 in nasal polyposis and chronic rhinosinusitis.	MMP2 MMP8	6.59e-05	4	116	2	21432777
Pubmed	Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts.	CD1B CD1C	6.59e-05	4	116	2	2701945
Pubmed	Phosphorylase Kinase Deficiency	PHKA1 PHKA2	6.59e-05	4	116	2	21634085
Pubmed	CD1-dependent dendritic cell instruction.	CD1B CD1C	6.59e-05	4	116	2	12415264
Pubmed	Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules.	CD1B CD1C	6.59e-05	4	116	2	18624350
Pubmed	Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal.	DLL1 NOTCH2	6.59e-05	4	116	2	32023464
Pubmed	HIV-1 Vif interaction with APOBEC3 deaminases and its characterization by a new sensitive assay.	APOBEC3G APOBEC3A	6.59e-05	4	116	2	21279453
Pubmed	Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer.	MDM2 DNMT1	6.59e-05	4	116	2	20570896
Pubmed	Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.	DLL1 NOTCH2	6.59e-05	4	116	2	32820046
Pubmed	p21-Activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2).	PAK6 MDM2	6.59e-05	4	116	2	23132866
Pubmed	Spectrin deficient inherited hemolytic anemias in the mouse: characterization by spectrin synthesis and mRNA activity in reticulocytes.	ANK1 SPTB	6.59e-05	4	116	2	6234993
Pubmed	Erythroid phosphatidyl serine exposure is not predictive of thrombotic risk in mice with hemolytic anemia.	ANK1 SPTB	6.59e-05	4	116	2	10772878
Pubmed	Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin.	NPHS1 INPPL1	6.59e-05	4	116	2	22194892
Pubmed	Notch controls the survival of memory CD4+ T cells by regulating glucose uptake.	DLL1 NOTCH2	6.59e-05	4	116	2	25501905
Pubmed	Aberrant splicing of the DMP1-ARF-MDM2-p53 pathway in cancer.	MDM2 DMP1	6.59e-05	4	116	2	26802432
Pubmed	Cleavage of phosphorylase kinase and calcium-free calmodulin by HIV-1 protease.	PHKA1 PHKA2	6.59e-05	4	116	2	1872871
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TUT7 CHD4 WDR3 DST SYNE2 YLPM1 ASCC3 NOP2 SDHA DNMT1	6.96e-05	653	116	10	22586326
Cytoband	22q13.1-q13.2	APOBEC3G APOBEC3A	3.79e-05	4	116	2	22q13.1-q13.2
Cytoband	1q22-q23	CD1B CD1C	4.85e-04	13	116	2	1q22-q23
GeneFamily	Acyl-CoA synthetase family	ACSL6 ACSL1 ACSBG1 ACSBG2 ACSL5	1.75e-07	26	91	5	40
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP27 MMP2 MMP8	2.31e-04	24	91	3	891
GeneFamily	NOP2/Sun RNA methyltransferase family	NSUN4 NOP2	5.18e-04	7	91	2	664
GeneFamily	Ankyrin repeat domain containing	ANK1 ARAP3 ASB11 ANKRD1 TANC1 NOTCH2	1.40e-03	242	91	6	403
GeneFamily	Apolipoprotein B mRNA editing enzyme catalytic subunits	APOBEC3G APOBEC3A	1.60e-03	12	91	2	406
GeneFamily	Synaptotagmins	SYT16 SYT14	3.24e-03	17	91	2	765
Coexpression	BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN	HSPH1 BNC1 ANKRD1 LRRFIP1	8.82e-06	30	115	4	M16101
Coexpression	BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN	HSPH1 BNC1 ANKRD1 LRRFIP1	8.82e-06	30	115	4	MM1096
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	LIMA1 MXRA5 SYNM OLFML2B HSPH1 CREB3L1 MMP8	4.89e-07	181	116	7	9b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCell	Epithelial_cells-Basal_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ABCC3 LIMA1 MXRA5 DLL1 DST LGR6 MMP2	8.94e-07	198	116	7	4235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 SYNE2 MICAL3 MCF2L ENPEP SDK1	1.09e-05	191	116	6	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 SYNE2 MICAL3 MCF2L ENPEP SDK1	1.09e-05	191	116	6	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ACSL1 ASB11 ANKRD1 LGR6	1.12e-05	192	116	6	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SPTB ACSL1 ASB11 ANKRD1 LGR6	1.12e-05	192	116	6	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	droplet-Fat-Mat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNM DLL1 PTPRB DST ARAP3 MCF2L	1.16e-05	193	116	6	54024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCell	droplet-Fat-Mat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNM DLL1 PTPRB DST ARAP3 MCF2L	1.16e-05	193	116	6	81d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 OLFML2B PLA2R1 TANC1 MMP2 DMP1	1.16e-05	193	116	6	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	medial-2-Hematologic-EREG+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	OLFML2B LCP2 APOBEC3A ACSL1 CD1B CD1C	1.19e-05	194	116	6	b2b4e4c3ac0df0d9f17b930ffb60c0fd85b3dd78
ToppCell	medial-Hematologic-EREG+_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	OLFML2B LCP2 APOBEC3A ACSL1 CD1B CD1C	1.19e-05	194	116	6	15f3b6b6579e388d0820f05e93a77ee1634bd6c3
ToppCell	medial-Hematologic-EREG+_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	OLFML2B LCP2 APOBEC3A ACSL1 CD1B CD1C	1.19e-05	194	116	6	1f3d22292d2691f93aa7b6770f5c250a33db3cc0
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNM DLL1 PTPRB DST ARAP3 MCF2L	1.19e-05	194	116	6	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	APOBEC3A ACSL1 HMCN2 ASB11 MMP8 CSMD1	1.23e-05	195	116	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	APOBEC3A ACSL1 HMCN2 ASB11 MMP8 CSMD1	1.23e-05	195	116	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ABCC3 LIMA1 DLL1 DST SYNE2 FAM83A	1.26e-05	196	116	6	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MXRA5 SLC22A15 MMP27 DLL1 MMP2 SDK1	1.26e-05	196	116	6	1bcae4e0a244af822e2b12b2026a2771316f107d
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	LIMA1 MXRA5 DLL1 DST SYNE2 LGR6	1.30e-05	197	116	6	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 OLFML2B CREB3L1 TANC1 MMP2 DMP1	1.38e-05	199	116	6	d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 OLFML2B CREB3L1 TANC1 MMP2 DMP1	1.38e-05	199	116	6	bf138cc692df727e087d140c014149ee5da00d9d
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PTPRB DST ARAP3 SYNE2 CNTNAP4 CSMD1	1.41e-05	200	116	6	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	LPS-IL1RA-Myeloid-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LCP2 ACSL1 NECAB3 MMP8 SDK1	1.45e-05	118	116	5	6053e19d040fb394f9c270361af07b0c5a4d47db
ToppCell	LPS-IL1RA-Myeloid-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LCP2 ACSL1 NECAB3 MMP8 SDK1	1.45e-05	118	116	5	811e8521129914eef46785a4227c1860e77d9096
ToppCell	LA-10._Endothelium_II\|World / Chamber and Cluster_Paper	ACSL6 PTPRB ARAP3 HMCN2 MCF2L	2.15e-05	128	116	5	071becbe97598c2b65580b0989eb664d6fd6c85a
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic-intermediate_monocyte\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCC3 OLFML2B LINC02913 APOBEC3A ACSL1	3.53e-05	142	116	5	9b39c778cfaf457303010f1b1cae8c0cd8fe5d1d
ToppCell	facs-Lung-18m-Hematologic-myeloid-leukocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PKD1L2 LCP2 FGF16 ZFYVE28 LGR6	5.04e-05	153	116	5	8cc2667213bfac37545bb63181e88ef1f1834413
ToppCell	facs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PKD1L2 LCP2 FGF16 ZFYVE28 LGR6	5.04e-05	153	116	5	596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF19 ANK1 YWHAG SYT14 ZNF324	5.53e-05	156	116	5	8349604bd801e20d33770f7d8243598c3756302b
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF19 PHKA1 PTPRB ARAP3 SYT14	5.53e-05	156	116	5	1928c86deb3bcd01db4ae76919a351066aadb39a
ToppCell	367C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NPHS1 OLFML2B PDE12 ARAP3 NAV2	5.70e-05	157	116	5	f511871e1a004c6e9af08ee325ab1bfc41807487
ToppCell	(08)_PNEC-(1)_24hpi\|(08)_PNEC / shred by cell type and Timepoint	ABCC3 YWHAG SDK1	5.81e-05	29	116	3	f1b59a0b6bce5772bfb084f08507cf775e7eae8c
ToppCell	367C-Lymphocytic-ILC-ILC-3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	OLFML2B ZNF7 PDE12 ARAP3 NAV2	6.42e-05	161	116	5	8de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DLL1 PPM1H ELMOD3 CSMD1 FAM83A	7.21e-05	165	116	5	0c80abf13409767825ef8a507b498afafa7e89c5
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TCF19 SYNM CD1B HMCN2 MCF2L	7.21e-05	165	116	5	3d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DLL1 PPM1H ELMOD3 CSMD1 FAM83A	7.21e-05	165	116	5	cced77f2d74b07010307d7f4788b8cf3fdaeb91a
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCF19 CYP4Z1 TANC1 SDK1 FAM83A	7.85e-05	168	116	5	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	DLL1 ARAP3 NAV2 ZFTA SDK1	7.85e-05	168	116	5	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	LIMA1 INPPL1 DLL1 SCNN1D NECAB3	8.07e-05	169	116	5	29db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK1 ACSL1 BNC1 ZKSCAN4 FAM83A	8.07e-05	169	116	5	08ac28c5ad8f5c5f9f54af341bf39e8f9417636e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	LIMA1 INPPL1 DLL1 SCNN1D NECAB3	8.07e-05	169	116	5	b1611e61f635f8f9b87250e026ad30999cbee041
ToppCell	E16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK1 ACSL1 BNC1 ZKSCAN4 FAM83A	8.07e-05	169	116	5	e5abd41db1e6724ad900e37658fa063b8e522908
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OLFML2B LGR6 CSMD1 SDK1 NOTCH2	8.53e-05	171	116	5	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	CTRL-Myeloid-Neutrophil\|CTRL / Disease state, Lineage and Cell class	LCP2 APOBEC3A ACSL1 ARAP3 SYNE2	8.77e-05	172	116	5	ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCell	facs-Spleen-nan-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A15 LCP2 PPM1H NAV2 FAM83A	9.26e-05	174	116	5	096bc6f1889f2bbadfe1e1a3eb6ae569aaa2ee7d
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INPPL1 DLL1 CREB3L1 NAV2 MUC2	9.51e-05	175	116	5	019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	OLFML2B MMP27 CREB3L1 FGF16 MMP2	9.77e-05	176	116	5	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	AT1-AT2_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	OVOS2 SYT16 DST ANKRD1 SYT14	9.77e-05	176	116	5	f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 CDHR3 SYNE2 CSMD1 ENPEP	9.77e-05	176	116	5	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SGSM1 SLC22A15 DLL1 DST CNTNAP4	1.00e-04	177	116	5	8dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SGSM1 SLC22A15 DLL1 DST CNTNAP4	1.00e-04	177	116	5	767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SGSM1 SLC22A15 DLL1 DST CNTNAP4	1.00e-04	177	116	5	5ef2527e9b41e62f1724cdabaad9d8979266bb7d
ToppCell	E18.5-Endothelial-Endothelial_lymphatic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SGSM1 SLC22A15 DLL1 DST CNTNAP4	1.00e-04	177	116	5	ae1d2fdd4f67f50c906b27ea084de058c6908aa2
ToppCell	BAL-Control-cDC_1\|Control / Compartment, Disease Groups and Clusters	APOBEC3G STAT2 APOBEC3A ACSL1 ACSBG2	1.00e-04	177	116	5	aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIPK4 SYNM SYT16 ANKRD1 CNTNAP4	1.03e-04	178	116	5	445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL TUT7 PTPRB SYNE2 ASCC3	1.03e-04	178	116	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC3 PPM1H SYNE2 MICAL3 SDK1	1.03e-04	178	116	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLL1 PLA2R1 PTPRB ARAP3 ZFTA	1.06e-04	179	116	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 SPTB PLA2R1 DST ENPEP	1.06e-04	179	116	5	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	LPS_only-Myeloid-Neutrophils\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LCP2 APOBEC3A ACSL1 MMP8 ACSL5	1.06e-04	179	116	5	d0a03e498afcfeb657037889685ecd77bed07e6c
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OVOS2 APOL5 CNTNAP4 ENPEP SDK1	1.06e-04	179	116	5	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	LPS_only-Myeloid-Neutrophils-Neutrophils\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LCP2 APOBEC3A ACSL1 MMP8 ACSL5	1.06e-04	179	116	5	d034651a5a355a58f5e15db627869f4feebdfe35
ToppCell	metastatic_Lymph_Node-T/NK_cells-Naive_CD8+_T\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ACSL6 HIPK4 SYNM APOBEC3G SYNE2	1.09e-04	180	116	5	16516dd9c78c27fc76f58d650de9851ffa0763e7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 PHKA1 ACSBG2 TANC1 SDK1	1.09e-04	180	116	5	8f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 OVOS2 APOL5 CNTNAP4 SDK1	1.09e-04	180	116	5	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 PHKA1 ACSBG2 TANC1 SDK1	1.11e-04	181	116	5	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 SPTB PLA2R1 DST ENPEP	1.11e-04	181	116	5	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 SPTB PLA2R1 DST ENPEP	1.11e-04	181	116	5	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	OLFML2B MMP27 CREB3L1 HMCN2 MMP2	1.14e-04	182	116	5	e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 OVOS2 LGR6 SDK1 NOTCH2	1.14e-04	182	116	5	d3a037268f026eb2f84428b1821022503cef7756
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	HMCN2 PKD2 LGR6 ENPEP SDK1	1.17e-04	183	116	5	818fd886e0188091310825f9145fa53328f2c979
ToppCell	facs-Skin-Telogen-3m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAK6 ACSL1 PDE12 ACSBG1 TANC1	1.17e-04	183	116	5	ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCell	droplet-Lung-nan-21m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIPK4 OLFML2B ANKRD1 LGR6 CSMD1	1.17e-04	183	116	5	b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNM LCP2 SYNE2 LGR6 DNMT1	1.17e-04	183	116	5	90c66ffd2c1f87c91f9a9886e28aeec542f9df85
ToppCell	droplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIPK4 OLFML2B ANKRD1 LGR6 CSMD1	1.17e-04	183	116	5	19e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 PKD1L2 CNTNAP4 CSMD1 SDK1	1.20e-04	184	116	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP27 CREB3L1 PHKA1 PLA2R1 ENPEP	1.20e-04	184	116	5	fea4fe648e9749177d0783443dc26a7df5807883
ToppCell	facs-Skin-nan-18m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL1 PDE12 GAS2L2 ACSBG1 NAV2	1.20e-04	184	116	5	dc7f6ee4062856a02423fff8b1cce62d46a9355c
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 PKD1L2 LCP2 PHKA1 HMCN2	1.20e-04	184	116	5	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	LCP2 APOBEC3A ACSL1 CSMD1 NOTCH2	1.20e-04	184	116	5	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 PKD1L2 CNTNAP4 CSMD1 SDK1	1.20e-04	184	116	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 PKD1L2 CNTNAP4 CSMD1 SDK1	1.20e-04	184	116	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP27 CREB3L1 PHKA1 PLA2R1 ENPEP	1.20e-04	184	116	5	96a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCell	facs-Skin-Skin_Anagen-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP27 CREB3L1 PHKA1 PLA2R1 ENPEP	1.20e-04	184	116	5	780eb72da43527f0c72effac3423ec7384f05f20
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 HIPK4 OLFML2B PLA2R1 MMP2	1.20e-04	184	116	5	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK1 SPTB HSPH1 ATG14 MICAL3	1.23e-04	185	116	5	e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANK1 PHKA1 ACSBG2 TANC1 SDK1	1.27e-04	186	116	5	948815663c212c4311329d503b5991cbbbff9808
ToppCell	Immune-enucleated_erythrocyte\|World / Lineage, Cell type, age group and donor	ANK1 SPTB HSPH1 ATG14 MICAL3	1.27e-04	186	116	5	f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL6 ANK1 SPTB ASB11 LGR6	1.27e-04	186	116	5	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL6 ANK1 SPTB ASB11 LGR6	1.27e-04	186	116	5	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 CDHR3 MICAL3 ENPEP SDK1	1.27e-04	186	116	5	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	Tuft\|World / Class top	LIMA1 ANK1 SPTB COPRS NAV2	1.27e-04	186	116	5	f4d83f15ab7b49c0920a322cd832413ece7c9948
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	LIMA1 OLFML2B HMCN2 MMP2 CSMD1	1.27e-04	186	116	5	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 CDHR3 SYNE2 MICAL3 SDK1	1.27e-04	186	116	5	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Tuft-tuft-2\|World / Class top	LIMA1 ANK1 SPTB COPRS NAV2	1.30e-04	187	116	5	4ec6eee866619dfe13c84f5d2e812bb380d37139
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 SPTB PLA2R1 DST ENPEP	1.30e-04	187	116	5	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMA1 TCF19 OLFML2B SYNE2 DNMT1	1.30e-04	187	116	5	14c239af77116d28d511dea754b6150d20488080
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	SGSM1 SYNM PTPRB ARAP3 MICAL3	1.30e-04	187	116	5	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	TUT7 LCP2 APOBEC3A ACSL1 NOTCH2	1.36e-04	189	116	5	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL6 ANK1 ASB11 ANKRD1 LGR6	1.36e-04	189	116	5	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 CDHR3 MICAL3 ENPEP SDK1	1.36e-04	189	116	5	3b48b0d220cc24d5170713d61fa91f5bb6c21841
Disease	Malignant neoplasm of breast	ANK1 ZSWIM5 MDM2 DLL1 APOBEC3A SETD2 ARAP3 SYNE2 LGR6 MMP2 ENPEP NOTCH2 LRRFIP1 DNMT1	5.73e-05	1074	112	14	C0006142
Disease	Glycogen phosphorylase kinase deficiency	PHKA1 PHKA2	8.53e-05	4	112	2	cv:C0268147
Disease	hereditary spherocytosis (is_implicated_in)	ANK1 SPTB	1.42e-04	5	112	2	DOID:12971 (is_implicated_in)
Disease	Hereditary spherocytosis	ANK1 SPTB	1.42e-04	5	112	2	cv:C0037889
Disease	Anemia, hereditary spherocytic hemolytic	ANK1 SPTB	1.42e-04	5	112	2	C0221409
Disease	adrenoleukodystrophy (is_marker_for)	ACSBG1 MMP2	1.42e-04	5	112	2	DOID:10588 (is_marker_for)
Disease	Mammary Carcinoma, Human	ZSWIM5 MDM2 DLL1 APOBEC3A SETD2 LGR6 MMP2 NOTCH2 DNMT1	1.81e-04	525	112	9	C4704874
Disease	Mammary Neoplasms, Human	ZSWIM5 MDM2 DLL1 APOBEC3A SETD2 LGR6 MMP2 NOTCH2 DNMT1	1.81e-04	525	112	9	C1257931
Disease	Mammary Neoplasms	ZSWIM5 MDM2 DLL1 APOBEC3A SETD2 LGR6 MMP2 NOTCH2 DNMT1	1.86e-04	527	112	9	C1458155
Disease	stromelysin-2 measurement	MMP27 MMP8	2.12e-04	6	112	2	EFO_0802095
Disease	Breast Carcinoma	ZSWIM5 MDM2 DLL1 APOBEC3A SETD2 LGR6 MMP2 NOTCH2 DNMT1	2.17e-04	538	112	9	C0678222
Disease	liver cirrhosis (biomarker_via_orthology)	MMP2 MUC2 DNMT1	2.92e-04	34	112	3	DOID:5082 (biomarker_via_orthology)
Disease	adrenoleukodystrophy (implicated_via_orthology)	ACSBG1 ACSBG2	2.96e-04	7	112	2	DOID:10588 (implicated_via_orthology)
Disease	clear cell renal cell carcinoma (is_implicated_in)	PAK6 SETD2	3.94e-04	8	112	2	DOID:4467 (is_implicated_in)
Disease	Hereditary spherocytosis	ANK1 SPTB	3.94e-04	8	112	2	C0037889
Disease	sarcoma (is_implicated_in)	MDM2 PTPRB	3.94e-04	8	112	2	DOID:1115 (is_implicated_in)
Disease	Arthritis, Collagen-Induced	ACSL1 ACSL5 DNMT1	4.75e-04	40	112	3	C0971858
Disease	Arthritis, Experimental	ACSL1 ACSL5 DNMT1	4.75e-04	40	112	3	C0993582
Disease	Arthritis, Adjuvant-Induced	ACSL1 ACSL5 DNMT1	4.75e-04	40	112	3	C0003865
Disease	glycogen storage disease (is_implicated_in)	PHKA1 PHKA2	5.05e-04	9	112	2	DOID:2747 (is_implicated_in)
Disease	abdominal aortic aneurysm (is_marker_for)	MMP2 MMP8	6.30e-04	10	112	2	DOID:7693 (is_marker_for)
Disease	theophylline measurement	YWHAG NAV2	6.30e-04	10	112	2	EFO_0021180
Disease	Liver Cirrhosis, Experimental	OLFML2B INPPL1 LCP2 YWHAG ACSL1 PKD2 MMP2 MMP8 ENPEP LRRFIP1	7.43e-04	774	112	10	C0023893
Disease	disease progression measurement, Crohn's disease	CDHR3 CSMD1 SDK1	7.64e-04	47	112	3	EFO_0000384, EFO_0008336
Disease	acute myeloid leukemia (is_marker_for)	ABCC3 MDM2 DNMT1	8.64e-04	49	112	3	DOID:9119 (is_marker_for)
Disease	intracranial aneurysm (is_implicated_in)	PKD2 MMP2	9.19e-04	12	112	2	DOID:10941 (is_implicated_in)
Disease	triacylglycerol 52:1 measurement	SLC22A15 CSMD1	1.26e-03	14	112	2	EFO_0010413
Disease	pancreatic ductal carcinoma (is_marker_for)	MDM2 MMP2 DNMT1	1.63e-03	61	112	3	DOID:3587 (is_marker_for)
Disease	Glycogen storage disease	PHKA1 PHKA2	1.87e-03	17	112	2	cv:C0017919
Disease	sphingomyelin 14:0 measurement	PAK6 SYNE2	1.87e-03	17	112	2	EFO_0010390
Disease	hypertrophic cardiomyopathy (is_marker_for)	MMP2 DNMT1	1.87e-03	17	112	2	DOID:11984 (is_marker_for)
Disease	cholangiocarcinoma (is_marker_for)	MDM2 MMP2 MUC2	1.87e-03	64	112	3	DOID:4947 (is_marker_for)
Disease	base metabolic rate measurement	MICAL3 ZKSCAN4	2.59e-03	20	112	2	EFO_0007777
Disease	triacylglycerol 46:1 measurement	SLC22A15 CSMD1	2.59e-03	20	112	2	EFO_0010401
Disease	nucleotide measurement	PTPRB SYNE2 ENPEP	2.73e-03	73	112	3	EFO_0010513
Disease	prothrombin time measurement	EDEM2 MCF2L	2.86e-03	21	112	2	EFO_0008390
Disease	triacylglycerol 48:2 measurement	SLC22A15 CSMD1	3.14e-03	22	112	2	EFO_0010405
Disease	triacylglycerol 48:3 measurement	SLC22A15 CSMD1	3.14e-03	22	112	2	EFO_0010406
Disease	Hepatitis	SYT16 NAV2	3.14e-03	22	112	2	HP_0012115
Disease	carotid artery disease (is_implicated_in)	MMP2 MMP8	3.14e-03	22	112	2	DOID:3407 (is_implicated_in)
Disease	Liver carcinoma	MBTPS1 TCF19 OLFML2B ARID2 CNTNAP4 MMP2 CSMD1	3.26e-03	507	112	7	C2239176
Disease	nighttime rest measurement	TANC1 CSMD1	3.73e-03	24	112	2	EFO_0007827
Disease	glioblastoma (is_implicated_in)	MDM2 PTPRB	3.73e-03	24	112	2	DOID:3068 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ETTEAIDDEGWLHSG	ACSBG2	481	Q5FVE4
TLWTSDQQDDDGGEG	YWHAG	231	P61981
EDTTQDAEHGAWALG	CREB3L1	106	Q96BA8
GESDLQSHSSEGVWL	ELMOD3	366	Q96FG2
HFGTDGADSLEAWTS	ARAP3	766	Q8WWN8
QNWDSLEIHDGGDVT	CSMD1	1851	Q96PZ7
LSEGFHQAGISDTLW	DNMT1	1151	P26358
LSGRWVCDDHNGDTS	ATG14	246	Q6ZNE5
TAEALDKDGWLHTGD	ACSL1	526	P33121
ESTAIHWASRGGNLD	ANKRD1	186	Q15327
WDGLDEHSQALSGRL	APOBEC3A	176	P31941
WDGLDEHSQDLSGRL	APOBEC3G	361	Q9HC16
EDSDATGHEWKLEGA	ANK1	1591	P16157
HSSWDSDGVSEEGTV	BNC1	871	Q01954
SDRNKSHEGTSGEWI	ARID2	251	Q68CP9
DITAGVELNDGQWHS	CNTNAP4	441	Q9C0A0
LELGASVDHGQWLDT	ASB11	216	Q8WXH4
DDLQIHGWDSDSGTA	CD1B	51	P29016
GWTEFEQLTLDGHNL	ALG1L	31	Q6GMV1
VGGDSHFDDDELWTL	MMP2	201	P08253
HFDDDELWTLGEGQV	MMP2	206	P08253
GGDAHFDAEETWTNT	MMP8	191	P22894
EDQGHLEDSWTALEG	ABCC3	856	O15438
LHLDGWEVGADDAET	ZFYVE28	486	Q9HCC9
GDTHFDEDENWTKDG	MMP27	191	Q9H306
SGALHLWNVTRADDG	NPHS1	701	O60500
EANLIGTGTSEHWVD	NOTCH2	1746	Q04721
STEDLHVTWSGANGD	PTPRB	831	P23467
AQSLGLLGDEHWATD	PAK6	111	Q9NQU5
TGAELDDDQHWSDSP	MICAL3	1096	Q7RTP6
HWVLDATFSDGSLGQ	MAGEC3	6	Q8TD91
WENPGLGAESHTDSL	LIMA1	76	Q9UHB6
AELSRGDGDVAWQHT	NGLY1	616	Q96IV0
NWTNERTLDDGLGHG	MBTPS1	236	Q14703
DLSLQEAGHGLWGET	HIPK4	431	Q8NE63
SSWEEGEHLGASAEP	HIPK4	521	Q8NE63
DDDSGLLVHCISGWD	MTMR14	321	Q8NCE2
ASGQWEAEDLHLDDE	LGR6	491	Q9HBX8
EWGSDLPSVESHLEN	DST	626	Q03001
WALARESGEALNGHS	HMCN2	4456	Q8NDA2
GDDQWGHLQLDATSV	PHKA1	126	P46020
PISLIWNHDSEDTEG	HSPH1	401	Q92598
DGHDTWGSFSLTLID	EDEM2	66	Q9BV94
GDQSGAIHIWDLKTD	MLST8	146	Q9BVC4
HGDTELDFSVVWDGD	PLXNA3	756	P51805
SDWINEDHPSSGSDD	MUC2	1306	Q02817
NGSIPEDHEDWASNG	PDE12	511	Q6L8Q7
DSDGELNTWELSEGT	COPRS	86	Q9NQ92
EGSEPALLHSWASAE	FAM83A	111	Q86UY5
PIADSLGWNDAGDHV	ENPEP	726	Q07075
LFNHAWEGGDEEDIS	OVOS2	1071	Q6IE36
GDSTQESESEEHWVG	DMP1	181	Q13316
SGLQASWASDHLELG	PKD1L2	451	Q7Z442
EAISHWELQSEGGQS	NSUN4	101	Q96CB9
DDDLWGDHSLEVEAG	APBB3	16	O95704
EDLTHALVWEGGSDP	CEFIP	1111	Q711Q0
DELQTHGWDSESGTI	CD1C	51	P29017
PHSENEDSDWLITGG	QRSL1	156	Q9H0R6
GEEWSQDLHSSGRTD	DLL1	156	O00548
SDLGDVSEEHGEWNK	CEP97	746	Q8IW35
GSLRSANWEEDELSG	CDHR3	831	Q6ZTQ4
VHEETDSWGTDAGNP	GAS2L2	421	Q8NHY3
EVNLLDTSTIHGDWG	EPHA8	31	P29322
TCEAIDEEGWLHTGD	ACSBG1	536	Q96GR2
TQEALDSDGWLHTGD	ACSL5	511	Q9ULC5
SLDQWHRSAGEEEDG	ARL6IP4	141	Q66PJ3
HSLEAPEDDGGWSSA	MCF2L	1021	O15068
HLSGEVGEEACSSWN	LINC02913	11	Q8NAJ2
ADGGFTELHSLWQNE	CHD4	1701	Q14839
QAEWNLGQDDSALHG	DENND1B	626	Q6P3S1
AFGDWLLTANGSEIH	SLC22A15	71	Q8IZD6
SELTLQWTEGHSGDT	SDK1	1916	Q7Z5N4
ALLPAAWEDSHGSQD	SCNN1D	406	P51172
GDDQWGHLQVDATSL	PHKA2	126	P46019
WSDLDGGNHTENVGE	LRRFIP1	411	Q32MZ4
QGDSLTSEDHLDDSW	NUP35	161	Q8NFH5
SGEEVLASLSGHWDR	OSBPL5	591	Q9H0X9
KGWLSLHTGNLDGED	MRPS24	66	Q96EL2
SLGLNSSGEEELNHW	SYT14	521	Q8NB59
SEGGITCSWVEHQDD	STAT2	606	P52630
ALGQNSSGEEEQDHW	SYT16	611	Q17RD7
DEQGSWGIDDLHISL	SYNE2	11	Q8WXH0
DLGSTHWKEQARSGE	SYNM	901	O15061
TVKGSDWLGDQDAIH	SDHA	126	P31040
LDWDLHGFSSSLGNV	FGF16	11	O43320
NPDLDAGVSEHSGDW	MDM2	221	Q00987
AGVSEHSGDWLDQDS	MDM2	226	Q00987
NTSLGLGDADSWDDS	NAV2	936	Q8IVL1
GLVHNGWDDLEFLSD	INPPL1	1216	O15357
EHEVEVNGTDTLWGE	TANC1	1066	Q9C0D5
VNHGDLWGSEDDADT	NOP2	126	P46087
GHSDVDFAVDENGLW	OLFML2B	616	Q68BL8
HVLSDAESGCQEGWE	PLA2R1	506	Q13018
SHEAFGGINWSEIEA	APOL5	211	Q9BWW9
TKEALDSDGWLHTGD	ACSL6	526	Q9UKU0
SVKGSWDDLVEGHNE	ASCC3	2041	Q8N3C0
ELLGDGSSITWEHLS	CYP4Z1	346	Q86W10
GDDWRVSLEDHSSQG	TCF19	66	Q9Y242
VWASDSGHEEESLSP	TULP1	11	O00294
VTFTGEEWGHLDLAQ	ZNF599	16	Q96NL3
DPTAGASIDDENCWH	ZSWIM5	321	Q9P217
STWDELGEALHAGEK	ZNF324	241	O75467
SSSGWEDEEFEEGHQ	TTC24	451	A2A3L6
HGSDDVLILATDGLW	PPM1H	426	Q9ULR3
HDKSGEWQETSGEIQ	WAPL	1066	Q7Z5K2
GHSEAATIAEWKDGL	SPTB	1761	P11277
GWRSSETEKHGQADS	SGSM1	871	Q2NKQ1
WESDDAASQISHGLG	PKD2	916	Q13563
DLGSSNWEAADLGNE	SMAP	21	O00193
TWESPGDDASLEHEA	SETD2	2421	Q9BYW2
GQTDWEKITDESGHL	YLPM1	2121	P49750
LWTIEDGIHSGACSD	ZNF350	66	Q9GZX5
NPEHGESWESQGRTE	ZKSCAN4	461	Q969J2
SLGSWHGAEDEEAPS	ZNF548	46	Q8NEK5
GNLLETIDAHDGALW	WDR3	486	Q9UNX4
VVIWEHTDSAAGDTG	TUT7	506	Q5VYS8
EVISNSWDAHLGLGA	ZFTA	161	C9JLR9
GFGDVSDSEVWLDSH	ZNF7	121	P17097
STWDELGEALHAGEK	ZNF324B	241	Q6AW86
ESHEEDNGGWSSFEE	LCP2	96	Q13094
HEETATEGWSAADVG	MXRA5	936	Q9NR99
EGASDTLEAQAHGWR	NECAB3	161	Q96P71