Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	2.79e-07	4	78	3	PF14914
Domain	LRRC37_N	LRRC37A LRRC37A3 LRRC37A2	2.79e-07	4	78	3	IPR032754
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	2.79e-07	4	78	3	IPR029423
Domain	LRRC37	LRRC37A LRRC37A3 LRRC37A2	2.79e-07	4	78	3	PF15779
Domain	LRRC37A/B-like	LRRC37A LRRC37A3 LRRC37A2	2.79e-07	4	78	3	IPR015753
Domain	Atg8	MAP1LC3B2 MAP1LC3B	4.74e-04	8	78	2	PF02991
Domain	Atg8-like	MAP1LC3B2 MAP1LC3B	4.74e-04	8	78	2	IPR004241
Domain	RhoGAP	ARHGAP36 ARHGAP29 ARAP2	2.22e-03	62	78	3	SM00324
Domain	RhoGAP	ARHGAP36 ARHGAP29 ARAP2	2.32e-03	63	78	3	PF00620
Domain	RHOGAP	ARHGAP36 ARHGAP29 ARAP2	2.43e-03	64	78	3	PS50238
Domain	RhoGAP_dom	ARHGAP36 ARHGAP29 ARAP2	2.43e-03	64	78	3	IPR000198
Domain	-	ARHGAP36 ARHGAP29 ARAP2	2.43e-03	64	78	3	1.10.555.10
Domain	SANT_dom	MIS18BP1 CRAMP1	5.24e-03	26	78	2	IPR017884
Domain	LRR_8	LRRC37A LRRC37A3 LRRC37A2 LRTM1	5.72e-03	171	78	4	PF13855
Domain	Rho_GTPase_activation_prot	ARHGAP36 ARHGAP29 ARAP2	5.96e-03	88	78	3	IPR008936
Domain	SANT	MIS18BP1 CRAMP1	6.07e-03	28	78	2	PS51293
Domain	Leu-rich_rpt_typical-subtyp	LRRC37A LRRC37A3 LRRC37A2 LRTM1	6.45e-03	177	78	4	IPR003591
Domain	LRR_TYP	LRRC37A LRRC37A3 LRRC37A2 LRTM1	6.45e-03	177	78	4	SM00369
Domain	SNF2_N	CHD8 BTAF1	7.87e-03	32	78	2	IPR000330
Domain	SNF2_N	CHD8 BTAF1	7.87e-03	32	78	2	PF00176
Pathway	REACTOME_RRNA_MODIFICATION_IN_THE_NUCLEUS_AND_CYTOSOL	RPS6 RPS7 RPS9 UTP14C	1.06e-04	60	58	4	M27613
Pathway	REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S	EIF4H RPS6 RPS7 RPS9	1.06e-04	60	58	4	M721
Pathway	REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S	EIF4H RPS6 RPS7 RPS9	1.45e-04	65	58	4	MM15416
Pathway	KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR_GRASP55	MAP1LC3B2 MAP1LC3B	2.47e-04	6	58	2	M47979
Pubmed	Multiple roles of integrin-α3 at the neuromuscular junction.	MAP1LC3B2 PCLO ITGA3 MAP1LC3B	1.47e-08	12	83	4	28386022
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A LRRC37A3 LRRC37A2	5.23e-08	4	83	3	22419166
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ATP6V1A MIS18BP1 EIF4ENIF1 EIF4H NFATC3 PHF12 BRPF1 RPS7 ARHGAP29 HERC2 FHIP1A MTMR9	8.62e-07	853	83	12	28718761
Pubmed	Ambra1 regulates autophagy and development of the nervous system.	MAP1LC3B2 PAX2 MAP1LC3B	1.09e-06	9	83	3	17589504
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A LRRC37A3 LRRC37A2	1.55e-06	10	83	3	23064749
Pubmed	Protein phosphatase 4 maintains the survival of primordial follicles by regulating autophagy in oocytes.	MAP1LC3B2 RPS6 MAP1LC3B	4.68e-06	14	83	3	39245708
Pubmed	Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	25421500
Pubmed	Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	27265145
Pubmed	Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	20889906
Pubmed	CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.	MIS18BP1 CENPC	5.63e-06	2	83	2	22540025
Pubmed	Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	38656870
Pubmed	Nonsense mediated decay factor UPF3B is associated with cMyBP-C haploinsufficiency in hypertrophic cardiomyopathy patients.	UPF3B MYBPC3	5.63e-06	2	83	2	37797718
Pubmed	Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	12088839
Pubmed	Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	22968077
Pubmed	[Preparation of an autophagy-targeted antituberculosis DNA vaccine encoding LpqH fused with LC3].	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	24909277
Pubmed	Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	28928467
Pubmed	Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	37047689
Pubmed	Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	32057231
Pubmed	Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	30349463
Pubmed	Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	31431059
Pubmed	Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B).	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	31577510
Pubmed	LC3 conjugation system in mammalian autophagy.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	15325588
Pubmed	LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy.	MAP1LC3B2 MAP1LC3B	5.63e-06	2	83	2	37315562
Pubmed	Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region.	EIF4H RPS6 RPS7 RPS9	8.08e-06	53	83	4	12588972
Pubmed	Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT).	CHD8 BTAF1 SUZ12 NCAPG2	9.37e-06	55	83	4	27114453
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MIS18BP1 GTF3C1 CENPC PHF12 BRPF1 CHD8 BTAF1 SUZ12 HERC2	1.50e-05	608	83	9	36089195
Pubmed	The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	28291748
Pubmed	Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	27636016
Pubmed	Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	28598240
Pubmed	Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.	HCN4 CASQ2	1.69e-05	3	83	2	29452352
Pubmed	Tumor endothelial expression of P-glycoprotein upon microvesicular transfer of TrpC5 derived from adriamycin-resistant breast cancer cells.	NFATC3 TRPC5	1.69e-05	3	83	2	24582564
Pubmed	Autophagy plays an essential role in cigarette smoke-induced expression of MUC5AC in airway epithelium.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	27036871
Pubmed	Microtubule-Associated Protein 1 Light Chain 3 (LC3) Isoforms in RPE and Retina.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	29721994
Pubmed	HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	29088262
Pubmed	Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	24095928
Pubmed	Autophagy proteins are modulated in the liver and hypothalamus of the offspring of mice with diet-induced obesity.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	27180121
Pubmed	ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	33459130
Pubmed	BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	33459136
Pubmed	Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus.	RPS6 PAX2	1.69e-05	3	83	2	22725947
Pubmed	Autophagy is required and protects against apoptosis during myoblast differentiation.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	24865278
Pubmed	Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat.	WNT7A KLF3	1.69e-05	3	83	2	10967130
Pubmed	Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	18069693
Pubmed	BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy.	MAP1LC3B2 MAP1LC3B	1.69e-05	3	83	2	24591579
Pubmed	Large neutral amino acid levels tune perinatal neuronal excitability and survival.	MAP1LC3B2 RPS6 MAP1LC3B	1.69e-05	21	83	3	36996814
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	RABEP2 ATP6V1A ATAD3A RPS6 RPS7 GPS1 RPS9 CHD8 ZNF318	1.84e-05	624	83	9	33729478
Pubmed	Immunochemical accessibility of ribosomal protein S4 in the 30 S ribosome. The interaction of S4 with S5 and S12.	RPS6 RPS7 RPS9	1.95e-05	22	83	3	6188845
Pubmed	Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.	FREM2 PAX2 ITGA3	2.24e-05	23	83	3	18787044
Pubmed	Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction.	MAP1LC3B2 RPS6 MAP1LC3B	2.90e-05	25	83	3	37812701
Pubmed	p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	30941888
Pubmed	Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	22095627
Pubmed	Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	32376415
Pubmed	Autophagy mediates tolerance to Staphylococcus aureus alpha-toxin.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	25816775
Pubmed	STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	33201170
Pubmed	The Hedgehog signalling pathway regulates autophagy.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	23149744
Pubmed	MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	26719147
Pubmed	The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	25301234
Pubmed	Structural arrangement of the codon-anticodon interaction area in human placenta ribosomes. Affinity labelling of the 40S subunits by derivatives of oligoribonucleotides containing the AUG codon.	RPS7 RPS9	3.37e-05	4	83	2	8318536
Pubmed	Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	32372061
Pubmed	Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	25669150
Pubmed	Aging is associated with hypermethylation of autophagy genes in macrophages.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	26909551
Pubmed	Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	21681844
Pubmed	Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	24200693
Pubmed	The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	18768753
Pubmed	Hepatocellular carcinoma-related cyclin D1 is selectively regulated by autophagy degradation system.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	29328502
Pubmed	Perturbation of PI3K/Akt signaling affected autophagy modulation in dystrophin-deficient myoblasts.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	34706731
Pubmed	Acetylation modulates LC3 stability and cargo recognition.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	30633346
Pubmed	Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	22055190
Pubmed	Autophagic compartments gain access to the MHC class II compartments in thymic epithelium.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	19915056
Pubmed	Autophagy exacerbates electrical remodeling in atrial fibrillation by ubiquitin-dependent degradation of L-type calcium channel.	MAP1LC3B2 MAP1LC3B	3.37e-05	4	83	2	30158642
Pubmed	Targeted next-generation sequencing (NGS) of nine candidate genes with custom AmpliSeq in patients and a cardiomyopathy risk group.	CASQ2 MYBPC3	3.37e-05	4	83	2	25892673
Pubmed	C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.	ATAD3A RPS6 SGF29	3.68e-05	27	83	3	29420262
Pubmed	Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival.	MAP1LC3B2 RPS6 MAP1LC3B	4.58e-05	29	83	3	36198274
Pubmed	Autophagy prior to chondrocyte cell death during the degeneration of Meckel's cartilage.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	22371349
Pubmed	CaV2.2 channel cell surface expression is regulated by the light chain 1 (LC1) of the microtubule-associated protein B (MAP1B) via UBE2L3-mediated ubiquitination and degradation.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	24566975
Pubmed	In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	26284655
Pubmed	Autophagy proteins are required for club cell structure and function in airways.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	31116580
Pubmed	Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	22863802
Pubmed	Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	21151103
Pubmed	Global Hypertranscription in the Mouse Embryonic Germline.	RPS9 TAF1D	5.60e-05	5	83	2	28591571
Pubmed	Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	25227738
Pubmed	Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	28916785
Pubmed	Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1.	MAP1LC3B2 MAP1LC3B	5.60e-05	5	83	2	29937374
Pubmed	Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes.	RPS6 RPS7 RPS9	6.18e-05	32	83	3	15883184
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EIF4ENIF1 PHF12 CHD8 PAX2 BTAF1 ITGA3 HERC2 DLL1 ABCA7 CRAMP1 TJP3	6.32e-05	1105	83	11	35748872
Pubmed	Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation.	MAP1LC3B2 RPS6 MAP1LC3B	6.79e-05	33	83	3	33436499
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	NFATC3 RPS7 RPS9 HERC2 MGME1	7.95e-05	183	83	5	36129980
Pubmed	Requirement of Lim1 for female reproductive tract development.	WNT7A PAX2	8.39e-05	6	83	2	14695376
Pubmed	Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	34524943
Pubmed	Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	24747438
Pubmed	Autophagy appears during the development of the mouse lower first molar.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	23052835
Pubmed	Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	22138575
Pubmed	p62 sequestosome 1/light chain 3b complex confers cytoprotection on lung epithelial cells after hyperoxia.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	23333919
Pubmed	Autophagy proteins regulate the secretory component of osteoclastic bone resorption.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	22055344
Pubmed	Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of Dab1-/-(yotari) Mice.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	36979337
Pubmed	OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	21383079
Pubmed	ADP-Ribosylation Factor-Interacting Protein 2 Acts as a Novel Regulator of Mitophagy and Autophagy in Podocytes in Diabetic Nephropathy.	MAP1LC3B2 MAP1LC3B	8.39e-05	6	83	2	38247505
Pubmed	Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.	RPS6 RPS7 RPS9	8.84e-05	36	83	3	8706699
Pubmed	Essential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics.	MAP1LC3B2 MAP1LC3B	1.17e-04	7	83	2	17077144
Pubmed	IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B.	MAP1LC3B2 MAP1LC3B	1.17e-04	7	83	2	38081361
Pubmed	Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells.	MAP1LC3B2 MAP1LC3B	1.17e-04	7	83	2	22510200
Cytoband	4p14	NWD2 KLF3 ARAP2	6.22e-05	42	83	3	4p14
Cytoband	Ensembl 112 genes in cytogenetic band chr4p14	NWD2 KLF3 ARAP2	2.51e-04	67	83	3	chr4p14
GeneFamily	S ribosomal proteins	RPS6 RPS7 RPS9	1.06e-04	34	49	3	728
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 RGL3 PCLO FHIP1A ARAP2	1.46e-06	189	83	6	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM4 FREM2 NFATC3 RGL3 ITGA3 FHIP1A	1.56e-06	191	83	6	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	ILEUM-inflamed-(2)_B_cell-(2)_Naive_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NFATC3 RPS6 RPS9 KLF3 ZNF318 TAF1D	1.70e-06	194	83	6	a89e67a40382600739be92e395bf47dd44aa4122
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-OPC_related-Oligodendrocyte/OPC\|1m / Sample Type, Dataset, Time_group, and Cell type.	RPS6 WNT7A RPS7 RPS9 LRTM1 DLL1	2.03e-06	200	83	6	80cec67b7557465320a847ba959a8a13f7c51566
ToppCell	(5)_Epithelial_cells-(5)_Epi_suprabasal\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	SBSPON RPS6 RPS7 RPS9 ITGA3 DLL1	2.03e-06	200	83	6	92382ca82da3e435ccbee1c73261d55164d54779
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-OPC_related\|1m / Sample Type, Dataset, Time_group, and Cell type.	RPS6 WNT7A RPS7 RPS9 LRTM1 DLL1	2.03e-06	200	83	6	8dafb90b418f91a0fb56c97db06233d3eca358dc
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4\|E18.5-samps / Age Group, Lineage, Cell class and subclass	MIS18BP1 FAM216B PRRT3 PAX2 NCAPG2	4.52e-06	130	83	5	169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	SHROOM4 RPS6 WNT7A RPS7 RPS9	1.44e-05	165	83	5	ecaeb90a6bc27524ef6f2eefa72aec7315dbde3b
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPSTI1 RPS6 RPS7 RPS9 TRIM59	1.76e-05	172	83	5	09c03cc7717373f10e51281be76d53979fcb7ccd
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RPS6 PLCH2 WNT7A DLL1 RMDN2	2.02e-05	177	83	5	75cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCell	Mid-temporal_gyrus_(MTG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NWD2 IQCA1 XIRP2 ARHGAP29 SCN3B	2.07e-05	178	83	5	ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NWD2 PLCH2 PCLO MEDAG	2.19e-05	180	83	5	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 RGL3 FHIP1A ARAP2	2.37e-05	183	83	5	c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NFATC3 PLCH2 WNT7A DLL1 RMDN2	2.37e-05	183	83	5	ec2af3402b51f11466d2a5783a6b33746b6a7fc9
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SBSPON WNT7A LRTM1 ITGA3 ABCA7	2.43e-05	184	83	5	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SBSPON WNT7A LRTM1 ITGA3 ABCA7	2.43e-05	184	83	5	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	XIRP2 SBSPON PCLO ARHGAP29 SCN3B	2.49e-05	185	83	5	241ea1e178fffef9e7df971de739e794332d5173
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQCA1 SBSPON RGL3 FHIP1A TJP3	2.62e-05	187	83	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	wk_15-18-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SBSPON WNT7A PCLO ARHGAP29 SCN3B	2.76e-05	189	83	5	f0418851ad4042c4cd87c8729e4f0d43bdf8fccb
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM4 FREM2 RGL3 ITGA3 FHIP1A	2.83e-05	190	83	5	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	ILEUM-inflamed-(2)_Naive_B_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RPS6 RPS7 RPS9 ZNF318 TAF1D	2.83e-05	190	83	5	a08d10f8145247d16c952a6f83957f5b57c6940b
ToppCell	LAM-Epithelial-AT1\|Epithelial / Condition, Lineage and Cell class	SBSPON WNT7A ARHGAP29 ITGA3 ABCA7	2.90e-05	191	83	5	3457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 RGL3 FHIP1A ARAP2	2.90e-05	191	83	5	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	IQCA1 SBSPON PCLO MEDAG SCN3B	2.98e-05	192	83	5	5e709c0714e8eba27e03a6def0544256bedb3ced
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 SBSPON PCLO MEDAG SCN3B	2.98e-05	192	83	5	b016e229300c183e14c0e2bba494bf49c7899112
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 SBSPON PCLO MEDAG SCN3B	2.98e-05	192	83	5	ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FREM2 RGL3 FHIP1A ARAP2 TJP3	2.98e-05	192	83	5	c15841f35e24d6ef6ce2a9a6dc62e66efdc3d9d5
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	IQCA1 SBSPON PCLO MEDAG SCN3B	2.98e-05	192	83	5	5f4f44f15d3a2846981e68296643a4634930a211
ToppCell	ILEUM-inflamed-(1)_Central_Memory_T_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RPS6 WNT7A RPS7 RPS9 KLF3	3.05e-05	193	83	5	c4975fff8927649669e93d3e04308cbf4a48e3e9
ToppCell	droplet-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6 RPS7 RPS9 KLF3 MAP1LC3B	3.05e-05	193	83	5	cba070019db30604ebddb610eedf92e48221ac58
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM4 FREM2 RGL3 ITGA3 FHIP1A	3.05e-05	193	83	5	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	droplet-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6 RPS7 RPS9 KLF3 MAP1LC3B	3.05e-05	193	83	5	07ddb9525b686c31fa7df4286557d1e58f7ead52
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FREM2 RGL3 PCLO PAX2 FHIP1A	3.13e-05	194	83	5	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FREM2 RGL3 PCLO PAX2 FHIP1A	3.13e-05	194	83	5	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	COVID-19_Convalescent-PLT_4\|COVID-19_Convalescent / Disease Group and Platelet Clusters	MIS18BP1 EPSTI1 EIF4H XIRP2 TAF1D	3.13e-05	194	83	5	ce1fad4e76a87f0c35e430ed1f2262395df882fd
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 RGL3 FHIP1A ARAP2	3.13e-05	194	83	5	6b286992d4bb56013c0ea5a7601d3476d806175a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 RGL3 FHIP1A ARAP2	3.13e-05	194	83	5	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_Central_Memory_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RPS6 WNT7A RPS9 KLF3 MAP1LC3B	3.21e-05	195	83	5	0a200e43e861d5a24c07244c576bba5d67efcf2d
ToppCell	Severe-B_naive-2\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RPS6 RPS7 RPS9 KLF3 TAF1D	3.29e-05	196	83	5	8ed9784684de0a31e4d20a79486e9b638d5a2605
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SBSPON WNT7A ITGA3 ABCA7 ARAP2	3.29e-05	196	83	5	6731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FREM2 RGL3 PCLO PAX2 FHIP1A	3.29e-05	196	83	5	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SBSPON WNT7A ITGA3 ABCA7 ARAP2	3.29e-05	196	83	5	6856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FREM2 RGL3 PCLO PAX2 FHIP1A	3.29e-05	196	83	5	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	Severe-B_naive-2\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RPS6 RPS7 RPS9 KLF3 TAF1D	3.29e-05	196	83	5	19687c52c0e8e00c9fb3df2898ac32bec1dc30ee
ToppCell	Mild/Remission-B_naive-2\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RPS6 RPS7 RPS9 KLF3 TAF1D	3.37e-05	197	83	5	0042716ba630e4d5142cca46fcb279a2e64370f2
ToppCell	tumor_Lung-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	PRUNE2 SBSPON RPS7 ARHGAP29 CASQ2	3.45e-05	198	83	5	f540f464118edc0fb809ebcb813d0302e6952253
ToppCell	Sigmoid-B_cell-Follicular_B_cell\|Sigmoid / Region, Cell class and subclass	RPS6 RPS7 RPS9 KLF3 ZNF318	3.45e-05	198	83	5	c3507fb508ace85a31dcff323f9e7ddb9ae6862e
ToppCell	Sigmoid-(2)_B_cell-(23)_Follicular_B_cell\|Sigmoid / shred on region, Cell_type, and subtype	RPS6 RPS7 RPS9 KLF3 ZNF318	3.45e-05	198	83	5	bfb1aa1450d1afb14b875e0cf6796e1a715b4605
ToppCell	(5)_Epi_suprabasal\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	SBSPON RPS6 RPS9 ITGA3 DLL1	3.53e-05	199	83	5	e1d0fd71b2f3925d02638413f2155db009f103d9
ToppCell	Transverse-T_cell-Tcm\|Transverse / Region, Cell class and subclass	RPS6 WNT7A RPS7 RPS9 KLF3	3.53e-05	199	83	5	b98964bdc707761dad94823510036e0af0ed1242
ToppCell	Healthy/Control\|World / Disease group and Cell class	CENPC RPS6 RPS7 RPS9 TAF1D	3.53e-05	199	83	5	2623c42b3e79e401a485879b52e8bbcbc581544d
ToppCell	Transverse-(1)_T_cell-(14)_Tcm\|Transverse / shred on region, Cell_type, and subtype	RPS6 WNT7A RPS7 RPS9 KLF3	3.53e-05	199	83	5	c885c53cc8d1382acc176c8029430d218ac41cc5
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 SBSPON TMEM106C CASQ2 ITGA3	3.62e-05	200	83	5	2bc7f462a551292de2501028164573935232f899
ToppCell	343B-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 SBSPON TMEM106C CASQ2 ITGA3	3.62e-05	200	83	5	4fb6fd703aca9a992924245105ad99163146a415
ToppCell	mLN-B_cell-Follicular_B_cell\|B_cell / Region, Cell class and subclass	RPS6 RPS7 RPS9 KLF3 ZNF318	3.62e-05	200	83	5	8fbd27ffcfd0702ad3c340d32455e36a01617139
ToppCell	343B-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 SBSPON TMEM106C CASQ2 ITGA3	3.62e-05	200	83	5	b50de1f8c8f598e281951e4587f2d96c11aac836
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 SBSPON TMEM106C CASQ2 ITGA3	3.62e-05	200	83	5	8b80a65b69b36ed405214564b939452c90aa40d6
ToppCell	Basal\|World / shred by cell class for bronchial biopsy	RPS6 RPS7 RPS9 RMDN2	1.12e-04	133	83	4	d8dd6d0fea5b2c0b1b60b648fa96524027b36e25
ToppCell	Mild/Remission-B_naive-1\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	LRRC37A LRTM1 ZNF318 CRAMP1	1.48e-04	143	83	4	bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPSTI1 LRTM1 KLF3 TRIM59	1.56e-04	145	83	4	a9f5a32abcf3eb2c66bd65f2521a6dd4ce56c635
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	LRRC37A PLCH2 ZNF318 FHIP1A	1.97e-04	154	83	4	e16f200391537aa1002b0079481b94e1fb86b9ad
ToppCell	normal_Lung-B_lymphocytes-Undetermined\|normal_Lung / Location, Cell class and cell subclass	PRUNE2 ZNF627 LRRC37A MAP1LC3B2	2.22e-04	159	83	4	f89fc18966d9b9b33e81e7b9eb3ec3420c20ff43
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SHROOM4 IQCA1 XIRP2 LRRC9	2.33e-04	161	83	4	46b5d80d2d521fb69752aba4c10383e715a32002
ToppCell	ILEUM-non-inflamed-(2)_B_cell-(2)_Naive_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RPS6 RPS9 KLF3 ZNF318	2.44e-04	163	83	4	9add806d706f7170a49b2c2dcc14343e9befd26c
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	EPSTI1 XIRP2 PLCH2 LRRC37A2	2.50e-04	164	83	4	362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A TMEM106C DLL1 LRRC9	2.56e-04	165	83	4	a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 FHIP1A LRRC9	2.56e-04	165	83	4	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 FREM2 FHIP1A LRRC9	2.56e-04	165	83	4	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 SBSPON CASQ2 MYBPC3	2.68e-04	167	83	4	91b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	SHROOM4 TRPC5 DLL1 RMDN2	2.74e-04	168	83	4	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SBSPON PAX2 ITGA3	2.74e-04	168	83	4	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	COVID-19_Moderate-NK_CD56bright\|World / disease group, cell group and cell class	IQCA1 PLCH2 DLL1 ARAP2	2.87e-04	170	83	4	caa6a534c1e9639caced9a51680f5c905f061bcc
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFAP47 PCLO ABCA7 MYBPC3	3.06e-04	173	83	4	46ed379571385684145b5cb6dd4ae340ac546e64
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SBSPON PLCH2 MEDAG MYBPC3	3.13e-04	174	83	4	76310c0af1d7df6a4de3816838b2ac2892f68746
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 FREM2 LRTM1 MEDAG	3.13e-04	174	83	4	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	ATP6V1A CENPC NT5C2 ARAP2	3.20e-04	175	83	4	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	AT1-AT2_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	SHROOM4 SBSPON WNT7A ABCA7	3.20e-04	175	83	4	9a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	RPS6 WNT7A RPS7 RPS9	3.20e-04	175	83	4	4b77e9cf712c9e3b4fb68462a96aea47be124e8d
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MIS18BP1 EPSTI1 CENPC TRIM59	3.20e-04	175	83	4	ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCell	facs-Heart-RV-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP2 LRTM1 CASQ2 MYBPC3	3.34e-04	177	83	4	692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCell	facs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP2 LRTM1 CASQ2 MYBPC3	3.34e-04	177	83	4	c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	SHROOM4 LRRC37A3 ARHGAP29 ZNF318	3.34e-04	177	83	4	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 FREM2 PCLO PAX2	3.41e-04	178	83	4	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 SBSPON ARHGAP29 PAX2	3.41e-04	178	83	4	544379f5a6145429762258d426b876bb36c112f5
ToppCell	Immune_cells-T_cells\|Immune_cells / Lineage and Cell class	EPSTI1 RPS6 RPS7 RPS9	3.41e-04	178	83	4	af420242277e2a4e2524002a2914b0538f79a134
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM4 FREM2 ITGA3 FHIP1A	3.48e-04	179	83	4	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	facs-BAT-Fat-24m-Lymphocytic-B_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RABEP2 RPS6 RPS7 RPS9	3.48e-04	179	83	4	932fc2bd62ff024068004825beda1ea493f2d650
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SBSPON RGL3 FHIP1A TJP3	3.48e-04	179	83	4	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PCLO ARHGAP29 MEDAG SCN3B	3.48e-04	179	83	4	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MIS18BP1 CENPC SUZ12 NCAPG2	3.56e-04	180	83	4	5e1680088065be14447d5d5465f91f7edd071a1e
ToppCell	facs-MAT-Fat-24m-Lymphocytic-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPSTI1 RPS7 RPS9 ARAP2	3.56e-04	180	83	4	f3f7a610db750fcb84d746a5ea0d8b57f9b7d901
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6 RPS7 RPS9 ZNF318	3.56e-04	180	83	4	243622eee35d38748e945677ff115616e763e3b4
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPSTI1 RPS6 RPS7 RPS9	3.56e-04	180	83	4	7a365af1fb3ac6b8f9588d042072ff7e374c3d55
ToppCell	droplet-Mammary_Gland-nan-18m-Lymphocytic-T_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPSTI1 RPS6 RPS7 RPS9	3.56e-04	180	83	4	7bdc040461f350dd3136219341b39679fbca317e
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPSTI1 RPS6 RPS7 RPS9	3.56e-04	180	83	4	89d3befbea2b4c06d118d6b339545ddcc1bcfacb
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6 RPS7 RPS9 ZNF318	3.56e-04	180	83	4	3a8d9a71efe113d1df3933902a625c0a56812074
ToppCell	facs-MAT-Fat-24m-Lymphocytic\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPSTI1 RPS7 RPS9 ARAP2	3.56e-04	180	83	4	bb2f1b254371924b2045e9e1a81b6dbf4f00dd6a
ToppCell	BL-critical-LOC-Lymphoid-NKT\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPS6 RPS7 RPS9 LRTM1	3.63e-04	181	83	4	e3add2412c9f8eddfb77e0fbcd66fe57b23ae513
ToppCell	(0)_Normal/No_Treatment\|World / Stress and Cell class	EPSTI1 RPS6 RPS7 RPS9	3.63e-04	181	83	4	4077282c45a37403f47e8d1b9ac102e6b1ba2cf9
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SBSPON RGL3 FHIP1A TJP3	3.63e-04	181	83	4	b45b11428d13950369347e051d4d517efb2bd4fd
Disease	Scoliosis, unspecified	ATAD3A DLL1	1.96e-04	8	79	2	C0036439
Disease	Brugada syndrome	HCN4 SCN3B	1.96e-04	8	79	2	cv:C1142166
Disease	cardiovascular disease	PRKAG3 RPS6 RGL3 NT5C2 PAX2 ZNF318 MYBPC3	2.27e-04	457	79	7	EFO_0000319
Disease	renal Wilms' tumor (is_implicated_in)	PAX2 SUZ12	3.14e-04	10	79	2	DOID:5176 (is_implicated_in)
Disease	Other specified cardiac arrhythmias	HCN4 SCN3B	3.83e-04	11	79	2	C0348626
Disease	Nodal rhythm disorder	HCN4 SCN3B	3.83e-04	11	79	2	C0264893
Disease	Ectopic rhythm	HCN4 SCN3B	3.83e-04	11	79	2	C1399226
Disease	CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)	HCN4 SCN3B	3.83e-04	11	79	2	C2748542
Disease	X-12707 measurement	RABEP2 SGF29	4.59e-04	12	79	2	EFO_0800720
Disease	Hypertrophic Cardiomyopathy	ATAD3A CASQ2 MYBPC3	4.87e-04	57	79	3	C0007194
Disease	cognitive behavioural therapy	DCLRE1C WNT7A NT5C2	5.13e-04	58	79	3	EFO_0007820
Disease	Brugada Syndrome 1	HCN4 SCN3B	5.42e-04	13	79	2	C4551804
Disease	Sinus Node Dysfunction (disorder)	HCN4 SCN3B	7.27e-04	15	79	2	C0428908
Disease	Schizoaffective disorder-bipolar type	PCLO SCN3B	8.29e-04	16	79	2	EFO_0009965
Disease	Female Urogenital Diseases	WNT7A PAX2	1.05e-03	18	79	2	C1720887
Disease	Brugada Syndrome (disorder)	HCN4 SCN3B	1.88e-03	24	79	2	C1142166
Disease	Malignant neoplasm of breast	LRRC37A RPS6 RPS7 RPS9 LRRC37A2 ARHGAP29 ZNF318 HERC2 DLL1	2.28e-03	1074	79	9	C0006142
Disease	Calcium channel blocker use measurement	TMEM106C RGL3 NT5C2 ZNF318	2.60e-03	213	79	4	EFO_0009930

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRIVQPSRPVKQLVL	CHD8	236	Q9HCK8
RHQLTRSISEIKPPN	NT5C2	521	P49902
IKNRIHRLPVLDPVS	PRKAG3	301	Q9UGI9
RHPIQVSRRLLSRPQ	ATAD3A	346	Q9NVI7
PVSVVLPRAQSKRRQ	FAM216B	121	Q8N7L0
ISPTGHRRRILKQLQ	ARAP2	51	Q8WZ64
DQRIRRQIHKPLTAV	IQCA1	756	Q86XH1
LQHRSQLLPQPRVRS	ABCA7	1751	Q8IZY2
PRFVRIVLSTLPNKH	NWD2	536	Q9ULI1
LIQEIQRRPRHAPSL	RABEP2	176	Q9H5N1
FQVPPHIQRQVAKRV	ARHGAP36	426	Q6ZRI8
PRLKPQTHLTSRQLL	LRRC9	1156	Q6ZRR7
RLIREQHPTKIPVII	MAP1LC3B	21	Q9GZQ8
AQRPRLQLKPRTVAT	EIF4H	206	Q15056
LPVESPDTQRKRRIH	KLF3	246	P57682
KTTAPRPDRVQTLHR	LRRC37A3	771	O60309
RPRVAAKTHERLLPQ	KRBA1	746	A5PL33
KPRPANLRHAIATVI	LRTM1	276	Q9HBL6
TPRLHITIPRRSKRN	MIS18BP1	346	Q6P0N0
KTTAPRPDRVQTLHR	LRRC37A2	771	A6NM11
KTTAPRPDRVQTLHR	LRRC37A	771	A6NMS7
LKIPLQRNVIPSVTR	MGME1	121	Q9BQP7
LIKTPRVDNVVLHRP	MTMR9	6	Q96QG7
TPVAVQHIRPARVKR	HERC2	2436	O95714
QHIRPARVKRRKQSP	HERC2	2441	O95714
RHHVVPITLRVNVRP	FREM2	921	Q5SZK8
EQNRAKPVHLVPRRL	EPSTI1	96	Q96J88
RKLPERLVHSRPLSQ	PCLO	4461	Q9Y6V0
EPARVRRSHLLVKPV	PIN1P1	51	O15428
RARPVINIVHKTLVP	ITGA3	461	P26006
RAAVLRNQIHVKSPP	GPS1	456	Q13098
PAVRTVLKIPQRVVH	OXA1L	336	Q15070
PSVVRRALQKHNVPQ	RGL3	641	Q3MIN7
QTPRHLKRLQSLIPS	HCN4	821	Q9Y3Q4
LVNTRHPKIRRQIEQ	MEDAG	136	Q5VYS4
NRIIRTKVQQPFHPT	PAX2	136	Q02962
RVVQVVKPHTPLIRF	MRPS36	11	P82909
DQKTPLRVLHRRPLA	PUS10	441	Q3MIT2
VERHTPRTKIRPVSL	ARHGAP29	1006	Q52LW3
RRLPPTLTKEQLQEH	UPF3B	56	Q9BZI7
PRVLQPFLTHRTKVA	FHIP1A	976	Q05DH4
SRNRIPLHIISIKPS	DCLRE1C	276	Q96SD1
GPPTERIRLQHQVKR	BTAF1	1361	O14981
HKLVLPSNTPNVRRT	CENPC	726	Q03188
VVCVRLRLQKHRPPA	DLL1	566	O00548
RHLRKPLVVQRTLLP	CRAMP1	881	Q96RY5
RPQQRSHISRTLPKP	KIAA1210	256	Q9ULL0
VKEHQRPTLRRLRPE	CASQ2	241	O14958
PVRPHNFVRENTKLI	CFAP47	3156	Q6ZTR5
HLTFIPTTPRRQLRV	PRRT3	151	Q5FWE3
RQRHIRVRKQVVNIP	RPS9	131	P46781
LIPHSDQRLRPQRTK	TMEM106C	71	Q9BVX2
IQRLVTPRVLQHKRR	RPS6	176	P62753
HVVFIAQRRILPKPT	RPS7	91	P62081
THPRRIKLTAPNINL	PRUNE2	2796	Q8WUY3
PVSPELRRQLEQHIK	SPATA31A6	586	Q5VVP1
RNPIRKFVRTPESVH	TAF1D	46	Q9H5J8
KHPPNRRVLQSVKRR	PHF12	361	Q96QT6
PVKRRNRHSLVGPQQ	SHKBP1	136	Q8TBC3
LIVRRRNAPVSRPHS	SHROOM4	86	Q9ULL8
SPQHRARKRRLPTIQ	RMDN2	121	Q96LZ7
IPPHRLSKITNRLTI	BRPF1	516	P55201
RNRQQRVTKSPAPVH	EIF4ENIF1	661	Q9NRA8
LPRRSPVHSKVREVL	NCAPG2	296	Q86XI2
IRKVAVPPRLSEHTQ	XIRP2	3121	A4UGR9
LPVIQRNPKRITTRH	UTP14C	746	Q5TAP6
RLIREQHPTKIPVII	MAP1LC3B2	21	A6NCE7
KPTTRVRRRSVQQEP	SBSPON	91	Q8IVN8
ERHTLSRRRVIPLPQ	SGF29	201	Q96ES7
RVPSASPLIQKINRR	SPATA8	81	Q6RVD6
QPRTLGHLPVIRRVK	PLCH2	1081	O75038
RNGPVKRTPITHILV	SUZ12	516	Q15022
PGLQRRPRHRIQSKQ	WASH4P	126	A8MWX3
RPRHRIQSKQRPLDE	WASH4P	131	A8MWX3
FKIPRRNISHIPERL	ZNF627	56	Q7L945
NTRVRLVFRVHIPQP	NFATC3	561	Q12968
HRPFVKTTRLIPLRV	SCN3B	131	Q9NY72
VRQVRPVTEKLPANH	ATP6V1A	211	P38606
RATRKPLVQTTPRLV	RNF121	121	Q9H920
NITVKRPRRIHLPAT	TJP3	86	O95049
VHVEPVRASRNKRPT	WNT7A	236	O00755
LVQKRVTIPRPHQIR	TRPC5	161	Q9UL62
HTLIRFLPRPIRQQL	GTF3C1	941	Q12789
KQATRSRPNLRVIPT	ZNF318	826	Q5VUA4
DVRQHVQILKQRPLP	TRIM59	256	Q8IWR1
PRLQLPRHLRQTIQK	MYBPC3	971	Q14896