Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	ATP5PB IFIH1 DNAH3 KIF15 DNAH10 ZGRF1 HELZ2 SMARCA4 CHD7 ABCC6 TP53	1.75e-05	614	75	11	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP5PB IFIH1 DNAH3 KIF15 DNAH10 HELZ2 SMARCA4 CHD7 ABCC6	3.98e-05	441	75	9	GO:0016887
GeneOntologyMolecularFunction	pyrophosphatase activity	ATP5PB IFIH1 DNAH3 KIF15 DNAH10 GARS1 HELZ2 SMARCA4 GBP1 CHD7 ABCC6	2.83e-04	839	75	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ATP5PB IFIH1 DNAH3 KIF15 DNAH10 GARS1 HELZ2 SMARCA4 GBP1 CHD7 ABCC6	2.86e-04	840	75	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ATP5PB IFIH1 DNAH3 KIF15 DNAH10 GARS1 HELZ2 SMARCA4 GBP1 CHD7 ABCC6	2.86e-04	840	75	11	GO:0016818
GeneOntologyMolecularFunction	helicase activity	IFIH1 ZGRF1 HELZ2 SMARCA4 CHD7	3.22e-04	158	75	5	GO:0004386
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ATP5PB IFIH1 DNAH3 KIF15 DNAH10 HELZ2 SMARCA4 GBP1 CHD7 ABCC6	6.20e-04	775	75	10	GO:0017111
GeneOntologyCellularComponent	centrosome	BICDL1 SLF1 KIF15 TCHP HIPK1 KHDC3L KIAA1217 DIAPH1 ANKRD26 NINL PBOV1 PLK4 TP53	3.72e-06	770	76	13	GO:0005813
GeneOntologyCellularComponent	microtubule organizing center	VIM BICDL1 SLF1 KIF15 TCHP HIPK1 KHDC3L KIAA1217 DIAPH1 ANKRD26 NINL PBOV1 PLK4 TP53	4.94e-06	919	76	14	GO:0005815
GeneOntologyCellularComponent	nuclear matrix	VIM SF3B1 SMARCA4 SMARCC2 TP53	1.58e-04	140	76	5	GO:0016363
GeneOntologyCellularComponent	type III intermediate filament	VIM DES	1.94e-04	6	76	2	GO:0045098
GeneOntologyCellularComponent	nuclear periphery	VIM SF3B1 SMARCA4 SMARCC2 TP53	3.99e-04	171	76	5	GO:0034399
GeneOntologyCellularComponent	inner dynein arm	DNAH3 DNAH10	5.76e-04	10	76	2	GO:0036156
GeneOntologyCellularComponent	bBAF complex	SMARCA4 SMARCC2	5.76e-04	10	76	2	GO:0140092
GeneOntologyCellularComponent	fascia adherens	DES ACTN1	9.91e-04	13	76	2	GO:0005916
GeneOntologyCellularComponent	npBAF complex	SMARCA4 SMARCC2	1.15e-03	14	76	2	GO:0071564
GeneOntologyCellularComponent	RSC-type complex	SMARCA4 SMARCC2	1.33e-03	15	76	2	GO:0016586
GeneOntologyCellularComponent	nBAF complex	SMARCA4 SMARCC2	1.51e-03	16	76	2	GO:0071565
GeneOntologyCellularComponent	intercalated disc	DES PIK3CA ACTN1	1.95e-03	68	76	3	GO:0014704
Domain	NPIP	NPIPA5 NPIPA1 NPIPA3 NPIPA7	2.46e-07	14	76	4	IPR009443
Domain	-	PDC PDCL	1.63e-05	2	76	2	1.10.168.10
Domain	Phosducin_N_dom	PDC PDCL	1.63e-05	2	76	2	IPR023196
Domain	MAM_1	TMPRSS15 PTPRK ALK	3.49e-05	16	76	3	PS00740
Domain	MAM	TMPRSS15 PTPRK ALK	5.06e-05	18	76	3	PF00629
Domain	MAM_dom	TMPRSS15 PTPRK ALK	5.06e-05	18	76	3	IPR000998
Domain	MAM_2	TMPRSS15 PTPRK ALK	5.06e-05	18	76	3	PS50060
Domain	Phosducin	PDC PDCL	9.75e-05	4	76	2	IPR001200
Domain	Phosducin	PDC PDCL	9.75e-05	4	76	2	PF02114
Domain	Phosducin_thioredoxin-like_dom	PDC PDCL	9.75e-05	4	76	2	IPR024253
Domain	BRK	SMARCA4 CHD7	2.43e-04	6	76	2	SM00592
Domain	BRK_domain	SMARCA4 CHD7	2.43e-04	6	76	2	IPR006576
Domain	BRK	SMARCA4 CHD7	2.43e-04	6	76	2	PF07533
Domain	Filament_head	VIM DES	3.39e-04	7	76	2	PF04732
Domain	Intermed_filament_DNA-bd	VIM DES	3.39e-04	7	76	2	IPR006821
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH10	1.44e-03	14	76	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH10	1.44e-03	14	76	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH10	1.44e-03	14	76	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH10	1.44e-03	14	76	2	PF08393
Domain	MT	DNAH3 DNAH10	1.44e-03	14	76	2	PF12777
Domain	AAA_8	DNAH3 DNAH10	1.44e-03	14	76	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH10	1.44e-03	14	76	2	IPR011704
Domain	AAA_5	DNAH3 DNAH10	1.44e-03	14	76	2	PF07728
Domain	DHC_fam	DNAH3 DNAH10	1.66e-03	15	76	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH10	1.66e-03	15	76	2	IPR004273
Domain	Dynein_heavy	DNAH3 DNAH10	1.66e-03	15	76	2	PF03028
Domain	TLC	TLCD1 TRAM1	1.89e-03	16	76	2	PS50922
Domain	TLC	TLCD1 TRAM1	1.89e-03	16	76	2	SM00724
Domain	TRAM_LAG1_CLN8	TLCD1 TRAM1	1.89e-03	16	76	2	PF03798
Domain	TLC-dom	TLCD1 TRAM1	1.89e-03	16	76	2	IPR006634
Domain	MAM	TMPRSS15 PTPRK	2.14e-03	17	76	2	SM00137
Domain	P-loop_NTPase	IFIH1 DNAH3 KIF15 DNAH10 ZGRF1 HELZ2 SMARCA4 GBP1 CHD7 ABCC6	2.23e-03	848	76	10	IPR027417
Domain	AAA+_ATPase	DNAH3 DNAH10 HELZ2 ABCC6	2.83e-03	144	76	4	IPR003593
Domain	AAA	DNAH3 DNAH10 HELZ2 ABCC6	2.83e-03	144	76	4	SM00382
Domain	-	IFIH1 DNAH3 DNAH10 ZGRF1 HELZ2 SMARCA4 GBP1 CHD7 ABCC6	3.21e-03	746	76	9	3.40.50.300
Domain	BRCT_dom	SLF1 SMARCC2	5.77e-03	28	76	2	IPR001357
Domain	SNF2_N	SMARCA4 CHD7	7.49e-03	32	76	2	IPR000330
Domain	SNF2_N	SMARCA4 CHD7	7.49e-03	32	76	2	PF00176
Domain	Chromo/shadow_dom	SMARCC2 CHD7	7.95e-03	33	76	2	IPR000953
Domain	CHROMO	SMARCC2 CHD7	7.95e-03	33	76	2	SM00298
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	ATP5PB VIM CRNKL1 SF3B1 NUP155 AGL GARS1 PTDSS1 DIAPH1 GEMIN4 SMARCA4 TRMT1 SMARCC2 ECI2 ACTN1 GRSF1 HNRNPH3	2.27e-08	1415	81	17	28515276
Pubmed	Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.	NPIPA5 NPIPA1 NPIPA3	4.86e-08	4	81	3	18055785
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TFEB KIF15 TCHP USP28 HIPK1 ZGRF1 KIAA1217 DIAPH1 ANKRD26 CHD7 TP53	1.22e-07	588	81	11	38580884
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CRNKL1 SF3B1 NUP155 INTS1 HELZ2 GEMIN4 SMARCA4 SMARCC2 CHD7 ACTN1 TP53	3.47e-07	653	81	11	22586326
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	VIM SETD1A CRNKL1 SF3B1 NUP155 GARS1 DIAPH1 GEMIN4 SMARCA4 SMARCC2 CHD7 SNX33 ACTN1 GRSF1 HNRNPH3	4.78e-07	1353	81	15	29467282
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	VIM CRNKL1 SF3B1 AGL GARS1 HELZ2 GEMIN4 SMARCA4 SMARCC2 TAOK1 CHD7 SNX33 ALK GRSF1 TP53	5.64e-07	1371	81	15	36244648
Pubmed	CHD7 cooperates with PBAF to control multipotent neural crest formation.	SMARCA4 SMARCC2 CHD7	6.76e-07	8	81	3	20130577
Pubmed	The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.	IFIH1 SMARCA4 SMARCC2	6.76e-07	8	81	3	28940253
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	VIM DES CRNKL1 BICDL1 GARS1 SMARCA4 ACTN1	1.00e-06	225	81	7	25277244
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	VIM SF3B1 NUP155 INTS1 DIAPH1 GEMIN4 SMARCA4 SMARCC2 TAOK1 CHD7	1.03e-06	582	81	10	20467437
Pubmed	LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.	VIM SF3B1 SMARCA4 SMARCC2 TP53	1.19e-06	79	81	5	26446488
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	VIM SETD1A CRNKL1 TMPRSS15 SF3B1 GARS1 INTS1 PTDSS1 DIAPH1 SMARCA4 TAOK1 CHD7 GRSF1 HNRNPH3	2.00e-06	1318	81	14	30463901
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	SETD1A SF3B1 NUP155 AGL GARS1 DIAPH1 SMARCA4 SMARCC2 HNRNPH3	2.31e-06	494	81	9	26831064
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ATP5PB VIM CRNKL1 SF3B1 NUP155 DIAPH1 GEMIN4 SMARCA4 ACTN1 TP53	2.35e-06	638	81	10	33239621
Pubmed	Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.	VIM SMARCA4 CHD7	3.42e-06	13	81	3	23319608
Pubmed	Clinical implications of genomic profiles in metastatic breast cancer with a focus on TP53 and PIK3CA, the most frequently mutated genes.	PIK3CA TP53	5.36e-06	2	81	2	28427202
Pubmed	High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast.	PIK3CA TP53	5.36e-06	2	81	2	29537649
Pubmed	Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1).	HIPK1 TP53	5.36e-06	2	81	2	12702766
Pubmed	A Comprehensive Survey of Genomic Alterations in Gastric Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets.	PIK3CA TP53	5.36e-06	2	81	2	31781598
Pubmed	Gene and protein expressions of vimentin and desmin during embryonic development of the mylohyoid muscle.	VIM DES	5.36e-06	2	81	2	22476899
Pubmed	Interaction of surfactant protein A with the intermediate filaments desmin and vimentin.	VIM DES	5.36e-06	2	81	2	18407667
Pubmed	TP53 and PIK3CA gene mutations in adenocarcinoma, squamous cell carcinoma and high-grade intraepithelial neoplasia of the cervix.	PIK3CA TP53	5.36e-06	2	81	2	25220666
Pubmed	Prognostic role of PIK3CA and TP53 in human papillomavirus-negative oropharyngeal cancers.	PIK3CA TP53	5.36e-06	2	81	2	29714670
Pubmed	An integrated investigation of structural and pathway alteration caused by PIK3CA and TP53 mutations identified in cfDNA of metastatic breast cancer.	PIK3CA TP53	5.36e-06	2	81	2	36563059
Pubmed	Transgenic mice carrying chimeric or mutated type III intermediate filament (IF) genes.	VIM DES	5.36e-06	2	81	2	9117989
Pubmed	Discordance of PIK3CA and TP53 mutations between breast cancer brain metastases and matched primary tumors.	PIK3CA TP53	5.36e-06	2	81	2	34876602
Pubmed	Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle.	VIM DES	5.36e-06	2	81	2	9314534
Pubmed	Plasma cell-free tumor DNA, PIK3CA and TP53 mutations predicted inferior endocrine-based treatment outcome in endocrine receptor-positive metastatic breast cancer.	PIK3CA TP53	5.36e-06	2	81	2	37344660
Pubmed	Positive selection of a gene family during the emergence of humans and African apes.	NPIPA1 NPIPA8	5.36e-06	2	81	2	11586358
Pubmed	The utility of TP53 and PIK3CA mutations as prognostic biomarkers in salivary adenoid cystic carcinoma.	PIK3CA TP53	5.36e-06	2	81	2	33290961
Pubmed	PIK3CA and TP53 mutations predict overall survival of stage II/III colorectal cancer patients.	PIK3CA TP53	5.36e-06	2	81	2	29434452
Pubmed	Comparison of the clinical and immunohistochemical features, including anaplastic lymphoma kinase (ALK) and p53, in inflammatory myofibroblastic tumours.	ALK TP53	5.36e-06	2	81	2	19589272
Pubmed	The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement.	ALK HNRNPH3	5.36e-06	2	81	2	30946933
Pubmed	Centrosome amplification causes microcephaly.	PLK4 TP53	5.36e-06	2	81	2	23666084
Pubmed	Effects of TP53 and PIK3CA mutations in early breast cancer: a matter of co-mutation and tumor-infiltrating lymphocytes.	PIK3CA TP53	5.36e-06	2	81	2	27369359
Pubmed	Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice.	SPI1 TP53	5.36e-06	2	81	2	24121269
Pubmed	SETD1A induced miRNA network suppresses the p53 gene expression module.	SETD1A TP53	5.36e-06	2	81	2	26865005
Pubmed	PIK3CA and TP53 gene mutations in human breast cancer tumors frequently detected by ion torrent DNA sequencing.	PIK3CA TP53	5.36e-06	2	81	2	24918944
Pubmed	Identification of human guanylate-binding protein 1 gene (hGBP1) as a direct transcriptional target gene of p53.	GBP1 TP53	5.36e-06	2	81	2	23727578
Pubmed	Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer.	PIK3CA TP53	5.36e-06	2	81	2	18270270
Pubmed	The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB.	TFEB TP53	5.36e-06	2	81	2	28292013
Pubmed	Comparison of mutational profiles between triple-negative and hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancers in T2N0-1M0 stage: Implications of TP53 and PIK3CA mutations in Korean early-stage breast cancers.	PIK3CA TP53	5.36e-06	2	81	2	35180531
Pubmed	Formation of cytoskeletal elements during mouse embryogenesis. Intermediate filaments of the cytokeratin type and desmosomes in preimplantation embryos.	VIM DES	5.36e-06	2	81	2	6161051
Pubmed	Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis.	PLK4 TP53	5.36e-06	2	81	2	26595384
Pubmed	SAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencing.	PLK4 TP53	5.36e-06	2	81	2	15967108
Pubmed	A single nucleotide polymorphism in PIK3CA gene is inversely associated with P53 protein expression in breast cancer.	PIK3CA TP53	5.36e-06	2	81	2	24908061
Pubmed	PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.	PIK3CA TP53	5.36e-06	2	81	2	28190247
Pubmed	Concomitant TP53 mutations with response to crizotinib treatment in patients with ALK-rearranged non-small-cell lung cancer.	ALK TP53	5.36e-06	2	81	2	30843662
Pubmed	Somatic mutations in SF3B1 aberrant-negative MDS-RS most commonly involved in TP53 genes.	SF3B1 TP53	5.36e-06	2	81	2	35582925
Pubmed	The role of p53 and anaplastic lymphoma kinase genes in the progression of cutaneous CD30(+) lymphoproliferative diseases.	ALK TP53	5.36e-06	2	81	2	15713979
Pubmed	S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis.	PIK3CA TP53	5.36e-06	2	81	2	31881983
Pubmed	Co-mutation of TP53 and PIK3CA in residual disease after neoadjuvant chemotherapy is associated with poor survival in breast cancer.	PIK3CA TP53	5.36e-06	2	81	2	30806788
Pubmed	Therapeutic Outcomes and Prognostic Impact of Gene Mutations Including TP53 and SF3B1 in Patients with Del(5q) Myelodysplastic Syndromes (MDS).	SF3B1 TP53	5.36e-06	2	81	2	35101379
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	ATP5PB VIM CRNKL1 TLCD1 NUP155 PTPRK TRAM1 GARS1 GLUD2 INTS1 SMARCA4 SMARCC2 TAOK1 SNX33	6.04e-06	1451	81	14	30550785
Pubmed	Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.	SOX5 SMARCA4 SMARCC2 CHD7	7.33e-06	53	81	4	21532573
Pubmed	The cleavage of host cell proteins by HIV-1 protease.	VIM DES ACTN1	8.08e-06	17	81	3	8997639
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	SETD1A SF3B1 SMARCA4 SMARCC2	1.29e-05	61	81	4	20305087
Pubmed	Ubiquitin-protein ligase E3C maintains non-small-cell lung cancer stemness by targeting AHNAK-p53 complex.	VIM ACTN1 TP53	1.57e-05	21	81	3	30503554
Pubmed	The mouse synemin gene encodes three intermediate filament proteins generated by alternative exon usage and different open reading frames.	VIM DES	1.60e-05	3	81	2	15265691
Pubmed	Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses.	PIK3CA TP53	1.60e-05	3	81	2	22923510
Pubmed	Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations, TP53 and microsatellite instability in endometrial cancer.	PIK3CA TP53	1.60e-05	3	81	2	23702729
Pubmed	Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: Correlation with clinical outcomes.	PIK3CA TP53	1.60e-05	3	81	2	28285689
Pubmed	SAPK pathways and p53 cooperatively regulate PLK4 activity and centrosome integrity under stress.	PLK4 TP53	1.60e-05	3	81	2	23653187
Pubmed	Genetic instability and recurrent MYC amplification in ALK-translocated NSCLC: a central role of TP53 mutations.	ALK TP53	1.60e-05	3	81	2	29885057
Pubmed	Epigenetic and genetic burden measures are associated with tumor characteristics in invasive breast carcinoma.	PIK3CA TP53	1.60e-05	3	81	2	27070496
Pubmed	Concomitant PI3K-AKT and p53 alterations in endometrial carcinomas are associated with poor prognosis.	PIK3CA TP53	1.60e-05	3	81	2	19234438
Pubmed	PIK3CA and p53 Mutations Promote 4NQO-Initated Head and Neck Tumor Progression and Metastasis in Mice.	PIK3CA TP53	1.60e-05	3	81	2	32152233
Pubmed	Whole-exome mutational landscape of neuroendocrine carcinomas of the gallbladder.	ALK TP53	1.60e-05	3	81	2	33563892
Pubmed	TP53, SF3B1, and NOTCH1 mutations and outcome of allotransplantation for chronic lymphocytic leukemia: six-year follow-up of the GCLLSG CLL3X trial.	SF3B1 TP53	1.60e-05	3	81	2	23435461
Pubmed	Circulating Tumor DNA Profiling From Breast Cancer Screening Through to Metastatic Disease.	PIK3CA TP53	1.60e-05	3	81	2	34849446
Pubmed	A microscopic landscape of the invasive breast cancer genome.	PIK3CA TP53	1.60e-05	3	81	2	27283966
Pubmed	PLK4 drives centriole amplification and apical surface area expansion in multiciliated cells.	USP28 PLK4	1.60e-05	3	81	2	35969030
Pubmed	Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA.	PIK3CA TP53	1.60e-05	3	81	2	17060456
Pubmed	SF3B1, RUNX1 and TP53 Mutations Significantly Impact the Outcome of Patients With Lower-Risk Myelodysplastic Syndrome.	SF3B1 TP53	1.60e-05	3	81	2	36117041
Pubmed	Survival prediction model for non-small cell lung cancer based on somatic mutations.	PIK3CA TP53	1.60e-05	3	81	2	32367667
Pubmed	Mouse models of PIK3CA mutations: one mutation initiates heterogeneous mammary tumors.	PIK3CA TP53	1.60e-05	3	81	2	23384338
Pubmed	THE SPECTRUM OF TP53, SF3B1, AND NOTCH1 MUTATIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS EXPOSED TO IONIZING RADIATION DUE TO THE CHORNOBYL NPP ACCIDENT.	SF3B1 TP53	1.60e-05	3	81	2	30582853
Pubmed	Frequencies of SF3B1, NOTCH1, MYD88, BIRC3 and IGHV mutations and TP53 disruptions in Chinese with chronic lymphocytic leukemia: disparities with Europeans.	SF3B1 TP53	1.60e-05	3	81	2	25605254
Pubmed	Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway.	USP28 TP53	1.60e-05	3	81	2	33226141
Pubmed	Predictive Value of the TP53/PIK3CA/ATM Mutation Classifier for Patients With Bladder Cancer Responding to Immune Checkpoint Inhibitor Therapy.	PIK3CA TP53	1.60e-05	3	81	2	34421886
Pubmed	Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.	SMARCA4 TP53	1.60e-05	3	81	2	29892061
Pubmed	53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms.	USP28 TP53	1.60e-05	3	81	2	27546791
Pubmed	Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice.	SPI1 SMARCA4	1.60e-05	3	81	2	19288495
Pubmed	Differential expression of immunohistochemical markers in bladder smooth muscle and myofibroblasts, and the potential utility of desmin, smoothelin, and vimentin in staging of bladder carcinoma.	VIM DES	1.60e-05	3	81	2	19252475
Pubmed	Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion.	PIK3CA TP53	1.60e-05	3	81	2	27402769
Pubmed	DNA Methylation Profiles of Ovarian Clear Cell Carcinoma.	PIK3CA TP53	1.60e-05	3	81	2	34697060
Pubmed	Aberrant anaplastic lymphoma kinase activity induces a p53 and Rb-dependent senescence-like arrest in the absence of detectable p53 stabilization.	ALK TP53	1.60e-05	3	81	2	21423761
Pubmed	Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors.	PIK3CA TP53	1.60e-05	3	81	2	25695693
Pubmed	SMARCB1-deficient and SMARCA4-deficient Malignant Brain Tumors With Complex Copy Number Alterations and TP53 Mutations May Represent the First Clinical Manifestation of Li-Fraumeni Syndrome.	SMARCA4 TP53	1.60e-05	3	81	2	35446794
Pubmed	p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress.	PLK4 TP53	1.60e-05	3	81	2	24498222
Pubmed	Predictive Role of TP53, PIK3CA and MLL2 in ER+ HER2+ Breast Bancer: Biomarker Analysis of Neo-ALL-IN [NCT 01275859].	PIK3CA TP53	1.60e-05	3	81	2	32988919
Pubmed	Short telomere length is associated with NOTCH1/SF3B1/TP53 aberrations and poor outcome in newly diagnosed chronic lymphocytic leukemia patients.	SF3B1 TP53	1.60e-05	3	81	2	23620080
Pubmed	[PI3-kinase mediates activity of RhoA and interaction of RhoA with mDia1 in thrombin-induced platelet aggregation].	PIK3CA DIAPH1	1.60e-05	3	81	2	20030946
Pubmed	Technical advance in targeted NGS analysis enables identification of lung cancer risk-associated low frequency TP53, PIK3CA, and BRAF mutations in airway epithelial cells.	PIK3CA TP53	1.60e-05	3	81	2	31711466
Pubmed	Simple and rapid in vivo generation of chromosomal rearrangements using CRISPR/Cas9 technology.	ALK TP53	1.60e-05	3	81	2	25456124
Pubmed	Mutations and karyotype in myelodysplastic syndromes: TP53 clusters with monosomal karyotype, RUNX1 with trisomy 21, and SF3B1 with inv(3)(q21q26.2) and del(11q).	SF3B1 TP53	1.60e-05	3	81	2	29249799
Pubmed	Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections.	PIK3CA TP53	1.60e-05	3	81	2	23583669
Pubmed	Vimentin knockout results in increased expression of sub-endothelial basement membrane components and carotid stiffness in mice.	VIM DES	1.60e-05	3	81	2	28912461
Pubmed	BRCA1 interaction of centrosomal protein Nlp is required for successful mitotic progression.	NINL TP53	1.60e-05	3	81	2	19509300
Pubmed	Inactivation of PLK4-STIL Module Prevents Self-Renewal and Triggers p53-Dependent Differentiation in Human Pluripotent Stem Cells.	PLK4 TP53	1.60e-05	3	81	2	30197118
Interaction	MAP1LC3B interactions	IFIH1 VIM SF3B1 NUP155 PTDSS1 DIAPH1 SMARCC2 ACTN1 PDCL STX11 HNRNPH3 TP53	1.13e-06	551	77	12	int:MAP1LC3B
Interaction	NES interactions	VIM DES SF3B1 FAM81B GARS1 CHD7 TP53	1.87e-06	152	77	7	int:NES
Interaction	ERG interactions	SF3B1 SPI1 HIPK1 SMARCA4 SMARCC2 CHD7 HNRNPH3	2.30e-05	223	77	7	int:ERG
Interaction	CHD7 interactions	SOX5 GARS1 SMARCA4 SMARCC2 CHD7 TP53	2.36e-05	150	77	6	int:CHD7
Interaction	LATS1 interactions	ATP5PB DES SF3B1 TCHP KIAA1217 ANKRD26 NINL TAOK1 TP53	4.51e-05	440	77	9	int:LATS1
Interaction	KDM1A interactions	ATP5PB VIM KIF15 USP28 ZGRF1 KIAA1217 GEMIN4 SMARCC2 CHD7 ECI2 STX11 TP53 CCDC33	5.28e-05	941	77	13	int:KDM1A
Interaction	SMARCD3 interactions	SETD1A CRNKL1 SMARCA4 SMARCC2 TP53	5.60e-05	107	77	5	int:SMARCD3
Interaction	BRCA1 interactions	DES SETD1A SF3B1 SLF1 NUP155 USP28 AGL GARS1 DIAPH1 ANKRD26 SMARCA4 NINL SMARCC2 HNRNPH3 TP53	6.53e-05	1249	77	15	int:BRCA1
Interaction	HSPB1 interactions	VIM DES CRNKL1 BICDL1 KIAA1217 GARS1 GEMIN4 SMARCA4 ACTN1 HNRNPH3 TP53	7.54e-05	708	77	11	int:HSPB1
Interaction	STIL interactions	TCHP KIAA1217 ANKRD26 NINL PLK4 TP53	8.83e-05	190	77	6	int:STIL
Interaction	HDLBP interactions	VIM SF3B1 AGL GARS1 SMARCA4 SMARCC2 TAOK1 CHD7 SNX33 ALK GRSF1 TP53	9.13e-05	855	77	12	int:HDLBP
Interaction	STIP1 interactions	ATP5PB VIM CRNKL1 SF3B1 NUP155 DIAPH1 GEMIN4 SMARCA4 SMARCC2 ACTN1 ANO3 HNRNPH3 TP53	1.04e-04	1006	77	13	int:STIP1
Interaction	FBXO32 interactions	VIM DES CRNKL1 NUP155 PIK3CA AGL SMARCA4 TRMT1	1.12e-04	386	77	8	int:FBXO32
Interaction	SIRT7 interactions	CRNKL1 SF3B1 NUP155 INTS1 HELZ2 GEMIN4 SMARCA4 SMARCC2 CHD7 ACTN1 TP53	1.17e-04	744	77	11	int:SIRT7
Interaction	WWOX interactions	ATP5PB SF3B1 NUP155 TCHP GARS1 DIAPH1 GEMIN4 SMARCA4 HNRNPH3 TP53	1.33e-04	627	77	10	int:WWOX
Interaction	MIB1 interactions	CRNKL1 NUP155 TCHP GEMIN4 ANKRD26 PLK4 TP53	1.34e-04	295	77	7	int:MIB1
Interaction	CHD3 interactions	ATP5PB SOX5 VIM SF3B1 KIF15 GEMIN4 SMARCA4 SMARCC2 PLK4 HNRNPH3 TP53	1.36e-04	757	77	11	int:CHD3
Interaction	CEP128 interactions	VIM TCHP ANKRD26 NINL PDCL PLK4 TP53	1.40e-04	297	77	7	int:CEP128
Interaction	TCHP interactions	VIM NUP155 TCHP NINL TP53	1.46e-04	131	77	5	int:TCHP
Interaction	ZBTB7A interactions	VIM SF3B1 SMARCA4 SMARCC2 TP53	1.46e-04	131	77	5	int:ZBTB7A
Interaction	SENP1 interactions	NUP155 USP28 HIPK1 TRMT1 TP53	1.46e-04	131	77	5	int:SENP1
Interaction	GATA4 interactions	ATP5PB SF3B1 DNAH10 SMARCA4 SMARCC2 CHD7 HNRNPH3 TP53	1.72e-04	411	77	8	int:GATA4
Cytoband	16p13.11	NPIPA5 NPIPA1 NPIPA3	9.13e-06	23	81	3	16p13.11
Cytoband	Ensembl 112 genes in cytogenetic band chr16p13	NPIPA5 NPIPA1 NPIPA3 NPIPA7 ABCC6	9.66e-04	426	81	5	chr16p13
Cytoband	5q15	SLF1 FAM81B	2.30e-03	40	81	2	5q15
Cytoband	1p13.2	ATP5PB HIPK1	3.03e-03	46	81	2	1p13.2
GeneFamily	Intermediate filaments Type III	VIM DES	6.30e-05	5	46	2	610
GeneFamily	TLC domain containing	TLCD1 TRAM1	2.81e-04	10	46	2	1374
GeneFamily	UPF1 like RNA helicases	ZGRF1 HELZ2	3.43e-04	11	46	2	1169
GeneFamily	Dyneins, axonemal	DNAH3 DNAH10	8.41e-04	17	46	2	536
GeneFamily	RNA binding motif containing	SETD1A PPARGC1B GRSF1 HNRNPH3	2.07e-03	213	46	4	725
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SETD1A KIF15 DNAH10 HIPK1 ABHD2 NPIPA3 CHD7	4.60e-08	184	81	7	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SETD1A KIF15 DNAH10 HIPK1 ABHD2 NPIPA3 CHD7	4.60e-08	184	81	7	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	SETD1A KIF15 DNAH10 HIPK1 ABHD2 NPIPA3 CHD7	4.60e-08	184	81	7	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SETD1A KIF15 DNAH10 HIPK1 ABHD2 NPIPA3 CHD7	4.60e-08	184	81	7	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SETD1A KIF15 DNAH10 HIPK1 ABHD2 NPIPA3 CHD7	4.60e-08	184	81	7	d31d4116d1d196633784863781fa45673607a421
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	SETD1A KIF15 DNAH10 HIPK1 ABHD2 NPIPA3 CHD7	8.13e-08	200	81	7	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	B_cells-ABCs\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SOX5 TFEB HELZ2 DIAPH1 GBP1 PLK4	1.05e-06	183	81	6	bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	SETD1A KIF15 DNAH10 ABHD2 NPIPA3 CHD7	1.08e-06	184	81	6	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	SETD1A KIF15 DNAH10 ABHD2 NPIPA3 CHD7	1.08e-06	184	81	6	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	9.14e-06	154	81	5	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	9.14e-06	154	81	5	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 ZBTB46 ANO3 ADCY6 TMEM200A	1.07e-05	159	81	5	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	1.99e-05	181	81	5	5a4574f1bfd0b4ca78da7effda43420857e17296
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	1.99e-05	181	81	5	a4e891603645f694687e68e585744ddc1a3c8697
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.05e-05	182	81	5	975f6275777fc578eba528e50f69891c66ec44ad
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.05e-05	182	81	5	f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.10e-05	183	81	5	b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|367C / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.10e-05	183	81	5	cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell	P07-Epithelial-airway_epithelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.16e-05	184	81	5	a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCell	P07-Epithelial-airway_epithelial_cell-club_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.16e-05	184	81	5	ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCell	P28-Epithelial-airway_epithelial_cell-club_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.27e-05	186	81	5	a26811481668fa25c48a064a56c198685693ad8d
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.27e-05	186	81	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	P28-Epithelial-airway_epithelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.27e-05	186	81	5	df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF15 ZGRF1 ACTN1 PLK4 ANO3	2.33e-05	187	81	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF15 ZGRF1 ACTN1 PLK4 ANO3	2.33e-05	187	81	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	Ciliated_cells-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.33e-05	187	81	5	bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDAH1 SLF1 PTPRK ACTN1 ANO3	2.52e-05	190	81	5	d594da827e3c16644952b9589cc12b947ce36279
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.58e-05	191	81	5	2a8e6d560907e71e9f6e190ca0667da804e25641
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.58e-05	191	81	5	46c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell	Mild_COVID-19-Epithelial-Ciliated\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.58e-05	191	81	5	995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.58e-05	191	81	5	a37f20172b85566b9039254a89680e37fd503fd5
ToppCell	BAL-Mild-Epithelial-Epithelial-Ciliated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.58e-05	191	81	5	2d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 PTPRK KIAA1217 FAM20A ABCC6	2.58e-05	191	81	5	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	SOX5 DDAH1 PTPRK KIAA1217 ABCC6	2.65e-05	192	81	5	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	SOX5 DDAH1 PTPRK KIAA1217 ABCC6	2.65e-05	192	81	5	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 DDAH1 PTPRK KIAA1217 ABCC6	2.71e-05	193	81	5	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.78e-05	194	81	5	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	wk_15-18-Epithelial-Proximal_epithelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.78e-05	194	81	5	b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	SOX5 DNAH3 DNAH10 PTPRK KIAA1217	2.85e-05	195	81	5	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SLF1 KIF15 ZGRF1 PLK4 STRIP2	2.85e-05	195	81	5	cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SOX5 DNAH3 DNAH10 PTPRK KIAA1217	2.85e-05	195	81	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Ciliated\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	2.85e-05	195	81	5	cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	SOX5 DNAH3 DNAH10 PTPRK KIAA1217	2.85e-05	195	81	5	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 DNAH10 ANO3 CCDC39 CCDC33	2.85e-05	195	81	5	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SLF1 KIF15 ZGRF1 PLK4 STRIP2	2.92e-05	196	81	5	df366d76ea55f49e349d622effa57c1535df8400
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	VIM PTPRK TSC22D3 ABHD2 ACTN1	2.92e-05	196	81	5	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	metastatic_Lymph_Node-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	SOX5 TFEB VIM DIAPH1 GBP1	2.92e-05	196	81	5	e1a9198bc51e01308f066323c5e089cfaf04b2ca
ToppCell	mild-Myeloid-Neutrophils_2\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IFIH1 SPI1 HELZ2 GBP1 ACTN1	2.92e-05	196	81	5	e9f30eb8a3915c3b2af009c832bff9b349b65ae5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 VIM DDAH1 ACTN1 ANO3	2.99e-05	197	81	5	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	control-Myeloid-Neutrophils_2\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IFIH1 SPI1 HELZ2 GBP1 ACTN1	2.99e-05	197	81	5	8819db1550bf14566c6d33d97f7f83419e867ace
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 DNAH10 ANO3 CCDC39 CCDC33	3.07e-05	198	81	5	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 DNAH10 ANO3 CCDC39 CCDC33	3.07e-05	198	81	5	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_interstitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IFIH1 SPI1 OTUD6A GBP1 STX11	3.07e-05	198	81	5	1259a6c14c85a406b7f4e9918ae148ee92b99f30
ToppCell	control-CD163+_Monocytes_(Sample_ID1_d7)\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	IFIH1 SPI1 HELZ2 GBP1 STX11	3.14e-05	199	81	5	933201d32eda12a89660bdbae9114a95cc428a38
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	3.22e-05	200	81	5	52aef65f01b06cd98056f17977efe525aee6eb6f
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	3.22e-05	200	81	5	55c148238d5c80c1faa3428a917ae8075be2c145
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	3.22e-05	200	81	5	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	3.22e-05	200	81	5	85c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	3.22e-05	200	81	5	e1dce91c6c531bb212002a14705e496d77ad3490
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 DNAH10 FAM81B CCDC39 CCDC33	3.22e-05	200	81	5	12bc7d95c4166d12487081a76d210b7abe5991b0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	FAM81B ABHD2 CCDC39 STRIP2 CCDC33	3.22e-05	200	81	5	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 FAM81B FAM20A CCDC33	6.61e-05	119	81	4	0cebbd44378c212aa0e18e4303f09eb315d02e11
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM81B GEMIN4 PBOV1 FAM20A	1.42e-04	145	81	4	c0894c738815ff54790caddb4bccfa1503fd555b
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC39	1.54e-04	148	81	4	d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCell	LPS-antiTNF-Epithelial_airway-Ciliated_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC39	1.54e-04	148	81	4	c8e93b87212f55774223caa385859c566fa1981f
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC33	1.66e-04	151	81	4	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC33	1.66e-04	151	81	4	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	Int-URO-Lymphocyte-T_NK-CD8_Naive\|Int-URO / Disease, Lineage and Cell Type	PTPRK SMARCC2 PLK4 TMEM200A	1.70e-04	152	81	4	52d6f9cf1f4637c922f582705d625b4cbe3dc0c2
ToppCell	COVID-19_Mild-PLT_5\|World / Disease Group and Platelet Clusters	ATP5PB ZGRF1 GBP1 NPIPA3	1.70e-04	152	81	4	90ba4e8a735ec8921038fa072129535f0e3fd9ae
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC33	1.79e-04	154	81	4	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC33	1.79e-04	154	81	4	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICDL1 STX11 PLK4 CCDC39	1.79e-04	154	81	4	75eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC33	1.83e-04	155	81	4	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DNAH10 FAM81B CCDC33	1.83e-04	155	81	4	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|390C / Donor, Lineage, Cell class and subclass (all cells)	BICDL1 SLF1 TSC22D3 TMEM200A	1.97e-04	158	81	4	ad0e2371c0bc6e53d22518aa3a401cddcde3759f
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX5 ABHD2 ABCC6 STRIP2	2.02e-04	159	81	4	e967b557fe6ae4879d36f62c0297cbf6a2ad1ce9
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAH10 NINL PLK4 TMEM200A	2.02e-04	159	81	4	2233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX5 ABHD2 ABCC6 STRIP2	2.02e-04	159	81	4	9db971130509c62d439e0cab16588a4d994d7aa0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF15 ZGRF1 DMRT1 PLK4	2.22e-04	163	81	4	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 ZBTB46 ANO3 TMEM200A	2.28e-04	164	81	4	f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_PSRC1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRK ANO3 TMEM200A STRIP2	2.33e-04	165	81	4	6de69b75174731931e7e80a3488f983a7ba4defe
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BICDL1 SPI1 GRSF1 STRIP2	2.38e-04	166	81	4	da10d0be6b616199d49dd922591c2901f9681583
ToppCell	COVID-19_Severe-CD4+_T_activated\|COVID-19_Severe / Disease condition and Cell class	IFIH1 HELZ2 ANKRD26 GBP1	2.38e-04	166	81	4	0f138dbafad6f83975944e8f6398411127b150cc
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRK NECTIN4 SNX33 ABCC6	2.49e-04	168	81	4	08f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCell	15-Distal-Epithelial-Multiciliated_cell\|Distal / Age, Tissue, Lineage and Cell class	DNAH10 FAM81B CCDC39 CCDC33	2.55e-04	169	81	4	425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B HIPK1 NECTIN4 ANO3	2.55e-04	169	81	4	8c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B HIPK1 NECTIN4 ANO3	2.55e-04	169	81	4	86041be5d3aeab5b9269f7912791b944f325a1b4
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NINL GBP1 ACTN1 CCDC39	2.61e-04	170	81	4	a121e10099faaeb60251eec162f38caf7c4238c2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIF15 ZGRF1 PLK4 ANO3	2.67e-04	171	81	4	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF15 ZGRF1 NPIPA7 CCDC33	2.67e-04	171	81	4	c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIF15 ZGRF1 PLK4 ANO3	2.67e-04	171	81	4	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Deuterosomal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 FAM81B CCDC39	2.73e-04	172	81	4	08ad76412c9cc3504141797b44b88478ced87476
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VIM CHD7 ANO3 ALK	2.73e-04	172	81	4	bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 ZBTB46 ANO3 TMEM200A	2.73e-04	172	81	4	08a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 ZBTB46 ANO3 TMEM200A	2.73e-04	172	81	4	553701349444eb366df3c11f54bb093434f153c6
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM4-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TFEB NECTIN4 FAM20A STRIP2	2.85e-04	174	81	4	fe105550a43b935affc73e32796115d20328a2f8
ToppCell	PCW_10-12-Epithelial-Epithelial_ciliated\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 FAM81B CCDC33	2.85e-04	174	81	4	b8d1c556290d188f56aeefc17f03119686945fe7
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 DDAH1 PTPRK ABCC6	2.85e-04	174	81	4	110369f6b78de34a6d934b5b47cecd023347bc80
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM4\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TFEB NECTIN4 FAM20A STRIP2	2.85e-04	174	81	4	9191f6abb37ca65da5105f91e21689d11ec1059b
ToppCell	PCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DNAH3 DNAH10 FAM81B CCDC33	2.85e-04	174	81	4	00cf27bc23af1472a507be31fba6245a8fdd901b
Disease	Sarcoma, Spindle Cell	PIK3CA SMARCA4 TP53	5.40e-06	14	74	3	C0205945
Disease	Sarcoma, Epithelioid	PIK3CA SMARCA4 TP53	5.40e-06	14	74	3	C0205944
Disease	Sarcoma	PIK3CA SMARCA4 TP53	1.95e-05	21	74	3	C1261473
Disease	Global developmental delay	INTS1 DIAPH1 TRMT1 SMARCC2 TAOK1	2.17e-05	133	74	5	C0557874
Disease	breast cancer (implicated_via_orthology)	PIK3CA SMARCA4 TP53	3.35e-05	25	74	3	DOID:1612 (implicated_via_orthology)
Disease	Malignant neoplasm of penis	PIK3CA TP53	3.71e-05	4	74	2	C0153601
Disease	Penile Neoplasms	PIK3CA TP53	3.71e-05	4	74	2	C0030849
Disease	Neoplasm of uncertain or unknown behavior of ovary	PIK3CA SMARCA4 TP53	5.28e-05	29	74	3	C0496920
Disease	Ovarian Carcinoma	PIK3CA SMARCA4 TP53	5.85e-05	30	74	3	C0029925
Disease	CHARGE syndrome (implicated_via_orthology)	CHD7 TP53	1.29e-04	7	74	2	DOID:0050834 (implicated_via_orthology)
Disease	Cutaneous Melanoma	PIK3CA ALK TP53	1.51e-04	41	74	3	C0151779
Disease	HEPATOCELLULAR CARCINOMA	PIK3CA TP53	2.21e-04	9	74	2	114550
Disease	uterine fibroid, Menorrhagia	DMRT1 TP53	2.21e-04	9	74	2	EFO_0000731, HP_0000132
Disease	Adult Hepatocellular Carcinoma	PIK3CA TP53	2.21e-04	9	74	2	C0279607
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA4 SMARCC2	2.21e-04	9	74	2	DOID:0050340 (implicated_via_orthology)
Disease	Hepatocellular carcinoma	PIK3CA TP53	2.21e-04	9	74	2	cv:C2239176
Disease	Carcinoma, Small Cell	SMARCA4 TP53	2.21e-04	9	74	2	C0262584
Disease	Head and Neck Carcinoma	PIK3CA TP53	2.76e-04	10	74	2	C3887461
Disease	Chronic Lymphocytic Leukemia	SF3B1 PIK3CA TP53	3.62e-04	55	74	3	C0023434
Disease	basal cell carcinoma (is_implicated_in)	CRNKL1 TP53	4.03e-04	12	74	2	DOID:2513 (is_implicated_in)
Disease	acute myeloid leukemia (implicated_via_orthology)	SF3B1 SPI1	4.03e-04	12	74	2	DOID:9119 (implicated_via_orthology)
Disease	Coffin-Siris syndrome	SMARCA4 SMARCC2	4.75e-04	13	74	2	C0265338
Disease	Adenocarcinoma Of Esophagus	PIK3CA TP53	5.54e-04	14	74	2	C0279628
Disease	Nephrosis	VIM DES	6.38e-04	15	74	2	C0027720
Disease	Non-Small Cell Lung Carcinoma	PIK3CA SMARCA4 ALK TP53	6.49e-04	156	74	4	C0007131
Disease	phosphatidylcholine measurement	SPI1 ZGRF1 NPIPA1 SMARCA4 CHD7	7.47e-04	284	74	5	EFO_0010226
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	DNAH10 GARS1 HELZ2 NPIPA1 SMARCA4	8.33e-04	291	74	5	EFO_0008317, EFO_0020946
Disease	Prostatic Neoplasms	VIM SF3B1 PTPRK PIK3CA USP28 CHD7 TP53	8.97e-04	616	74	7	C0033578
Disease	Malignant neoplasm of prostate	VIM SF3B1 PTPRK PIK3CA USP28 CHD7 TP53	8.97e-04	616	74	7	C0376358
Disease	brain infarction	SNX33 ALK	9.25e-04	18	74	2	EFO_0004277
Disease	Pancreatic carcinoma	TCHP TP53	1.03e-03	19	74	2	C0235974
Disease	hepatocellular carcinoma (is_implicated_in)	SF3B1 PIK3CA SMARCA4 TP53	1.13e-03	181	74	4	DOID:684 (is_implicated_in)
Disease	BREAST CANCER	PIK3CA TP53	1.26e-03	21	74	2	114480
Disease	Stomach Carcinoma	TCHP PIK3CA	1.26e-03	21	74	2	C0699791
Disease	Glioma	PIK3CA ALK TP53	1.38e-03	87	74	3	C0017638
Disease	colorectal carcinoma (is_implicated_in)	PIK3CA TP53	1.39e-03	22	74	2	DOID:0080199 (is_implicated_in)
Disease	Nasopharyngeal carcinoma	PIK3CA TP53	1.39e-03	22	74	2	C2931822
Disease	Carcinoma of lung	PIK3CA TP53	1.52e-03	23	74	2	C0684249
Disease	response to peginterferon alfa-2a	ANKRD26 DMRT1	1.79e-03	25	74	2	EFO_0010103
Disease	Mammary Carcinoma, Human	VIM DES PPARGC1B PIK3CA ALK TP53	2.06e-03	525	74	6	C4704874
Disease	Mammary Neoplasms, Human	VIM DES PPARGC1B PIK3CA ALK TP53	2.06e-03	525	74	6	C1257931
Disease	coronary artery disease (is_implicated_in)	DDAH1 ABCC6 TP53	2.06e-03	100	74	3	DOID:3393 (is_implicated_in)
Disease	Colorectal cancer	PIK3CA TP53	2.09e-03	27	74	2	cv:C0346629
Disease	COLORECTAL CANCER	PIK3CA TP53	2.09e-03	27	74	2	114500
Disease	Neoplasm of the large intestine	PIK3CA TP53	2.09e-03	27	74	2	cv:C0009404
Disease	Hereditary non-polyposis colorectal cancer syndrome	PIK3CA SMARCA4	2.09e-03	27	74	2	C1112155
Disease	Malignant tumor of breast	PIK3CA TP53	2.09e-03	27	74	2	cv:C0006142
Disease	Breast neoplasm	PIK3CA TP53	2.09e-03	27	74	2	cv:C1458155
Disease	Sezary Syndrome	SMARCA4 TP53	2.09e-03	27	74	2	C0036920
Disease	Familial cancer of breast	PIK3CA TP53	2.09e-03	27	74	2	cv:C0346153
Disease	Mammary Neoplasms	VIM DES PPARGC1B PIK3CA ALK TP53	2.10e-03	527	74	6	C1458155
Disease	Neoplasm Metastasis	VIM PIK3CA ALK TP53	2.19e-03	217	74	4	C0027627
Disease	Pigmented Basal Cell Carcinoma	PIK3CA TP53	2.25e-03	28	74	2	C1368275
Disease	Breast Carcinoma	VIM DES PPARGC1B PIK3CA ALK TP53	2.32e-03	538	74	6	C0678222
Disease	Carcinoma, Basal Cell	PIK3CA TP53	2.41e-03	29	74	2	C4721806
Disease	Hereditary Nonpolyposis Colorectal Cancer	PIK3CA SMARCA4	2.41e-03	29	74	2	C1333990
Disease	Hematopoetic Myelodysplasia	SF3B1 TP53	2.41e-03	29	74	2	C2713368

Protein segments in the cluster

Peptide	Gene	Start	Entry
MHAMQQKLEDFRDYR	ACTN1	306	P12814
HDTEMNNYRRAMQKM	CCDC33	631	Q8N5R6
MKMIEQHNQEYREGK	CTSL3P	1	Q5NE16
DYAMRLMEQMKHINE	ADCY6	1061	O43306
MQIDDNVMRKFHGYN	ABHD2	301	P08910
VYHMDMEAQRKNLQL	FAM186B	661	Q8IYM0
TYVDEVHKNNRSDMM	ANKRD26	391	Q9UPS8
DAQEQYNKLRMMHSN	DIAPH1	1096	O60610
LERNQDMSRQYEQMH	BICDL1	121	Q6ZP65
QRSYKRQQMRQEALM	CHD7	1921	Q9P2D1
RLDYHISVQNMMRRK	ATP5PB	196	P24539
MMYEAELEHLQQQRR	ANO3	956	Q9BYT9
MYSQDFHIQQVERRM	CCDC39	451	Q9UFE4
VQKALEKHRMYMGQR	GRSF1	206	Q12849
KEIHTYMEMFQRAQA	NPIPA1	176	Q9UND3
MQDLARYRQQLEHIM	KIAA0895L	441	Q68EN5
QDVARMEAEMAQKHR	OTUD6A	46	Q7L8S5
YNFKMRQLEHVMDSA	KIF15	1121	Q9NS87
LEQNIMDKNYMAHLV	INTS1	1276	Q8N201
FQNMEICKRRVHMYD	HIPK1	536	Q86Z02
PHYNRRRKDNDIAMM	TMPRSS15	866	P98073
RKYRRQCMQDMHQKL	PDC	91	P20941
MSKDKNNMQHRYIEL	HNRNPH3	251	P31942
MMEQKERSYQEHLKQ	GBP1	516	P32455
RVRAMAIYKQSQHMT	TP53	156	P04637
KEIHTYMEMFQRAQA	NPIPA3	176	F8WFD2
MDQSHRKEMQLYNSI	CYHR1	206	Q6ZMK1
GMYLKHLNRQVEAME	PIK3CA	696	P42336
RMAKVDQNRVRYMDL	NUP155	1066	O75694
LKMVQGDYRHEMNLL	FAM81B	281	Q96LP2
KYAEMEMKNRQVNHA	CRNKL1	281	Q9BZJ0
NSKRQEVAMMRNRYL	DNAH3	2666	Q8TD57
QAKQEMMEYRHQIQS	DES	316	P17661
NIMRHYLMQKLKNNR	IFIH1	456	Q9BYX4
KMIMNLADYHRQLQA	KHDC3L	101	Q587J8
KNAINTEMYHEIMRA	ECI2	161	O75521
AHIMVKEYMIQFNRL	HELZ2	1521	Q9BYK8
ENRQYLHKMQVLEMI	CCDC198	146	Q9NVL8
HMIKMYDNIASLRFN	DNAH10	1591	Q8IVF4
QAMKNYGRKMHRQID	DNAH10	1706	Q8IVF4
LAQLRAHMADMEAKY	CCDC153	141	Q494R4
KALKIMQQMSDHRYD	DDAH1	196	O94760
RSARQIMHTAMKYNL	GLUD2	516	P49448
KNMENRHAMSSQYRM	DMRT1	276	Q9Y5R6
RQEMTHMVNAMDRSY	PTPRK	791	Q15262
MRAFLRNQKYEDMHN	PBOV1	1	Q9GZY1
FLQQYRKQRMEEMRQ	PDCL	136	Q13371
KEIHTYMEMFQRAQA	NPIPA7	176	E9PJI5
KEIHTYMEMFQRAQA	NPIPA8	176	P0DM63
ADARMLMYQHQRVSE	TRMT1	211	Q9NXH9
QRERMQQQAVMHYMQ	TFEB	21	P19484
TMSAIYQKVRHRMND	STRIP2	731	Q9ULQ0
HTLRIKEQRQMNGMY	TMEM200A	171	Q86VY9
QAMDLVKNHLMYAVR	TSC22D3	56	Q99576
FEQQNMYRLKVLQMR	ABCC6	366	O95255
KEIHTYMEMFQRAQA	NPIPA5	176	E9PKD4
RHKMYREQMNLTSLD	FAM20A	136	Q96MK3
KLRFRQHMENEMAHY	GARS1	426	P41250
QEDMQAMVQLIRYMH	PPARGC1B	281	Q86YN6
QLHQLRAQIMAYKML	SMARCA4	176	P51532
QRRELDFKHMMQNYL	SNX33	536	Q8WV41
DFKHMMQNYLRQQIL	SNX33	541	Q8WV41
QAEMHMEQSLYRQKS	KIAA1217	441	Q5T5P2
REQMSGYKRMRRQHQ	TAOK1	461	Q7L7X3
GYKRMRRQHQKQLMT	TAOK1	466	Q7L7X3
LQQLYRHMELEQMHV	SPI1	81	P17947
MMEQVKEHYQDLRTQ	NINL	621	Q9Y2I6
MCHNGEMNRYLKNRV	PLK4	91	O00444
NIRQMVADMREKRYV	SETD1A	1601	O15047
RQAFHMEQLKYAEMR	SMARCC2	931	Q8TAQ2
MEQLKYAEMRARQQH	SMARCC2	936	Q8TAQ2
MIVYRRKHQELQAMQ	ALK	1056	Q9UM73
KMNARTYMDVMREQH	SF3B1	146	O75533
RAMHDYNQAEMKQRD	STX11	141	O75558
NMKEEMARHLREYQD	VIM	371	P08670
QRSMHAYQREKMKEE	TCHP	61	Q9BT92
HTEKRNIMFMQELQY	USP28	206	Q96RU2
TMYRTQKEMQNHEDV	SLF1	241	Q9BQI6
MMKISNAQDHLLYRV	TLCD1	156	Q96CP7
VIQEYMLDKINRRMH	TRAM1	96	Q15629
HLQMIKGMLYQQRQD	ZGRF1	1201	Q86YA3
KAIMRNRRQEMRQYF	SOX5	646	P35711
LAMHRNAYKRMSQIQ	XKRX	161	Q6PP77
NYKMHFRMINEQQVE	PTDSS1	16	P48651
MNNRKEDMEITSHYR	ZBTB46	1	Q86UZ6
EAMQKHMQGIQFRER	AGL	1206	P35573
IQQKMDRHMEVCYIF	GEMIN4	411	P57678
MSRYHRRKAQQMTQK	NECTIN4	371	Q96NY8