Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation termination factor activity

ETF1 GSPT1 GSPT2

6.08e-0671133GO:0008079
GeneOntologyMolecularFunctiontranslation release factor activity

ETF1 GSPT1 GSPT2

6.08e-0671133GO:0003747
GeneOntologyMolecularFunctionhistone H3K36 trimethyltransferase activity

SETD2 SETD5

3.14e-0451132GO:0140955
GeneOntologyMolecularFunctioncreatine kinase activity

CKB CKM

4.69e-0461132GO:0004111
GeneOntologyCellularComponenttranslation release factor complex

ETF1 GSPT1 GSPT2

1.54e-0731133GO:0018444
Domain-

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

1.31e-05679112153.30.160.60
DomainZINC_FINGER_C2H2_2

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF608 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

1.52e-0577511216PS50157
DomainZINC_FINGER_C2H2_1

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF608 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

1.57e-0577711216PS00028
Domainzf-C2H2

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

1.66e-0569311215PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

1.69e-0569411215IPR013087
DomainZnf_C2H2-like

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF608 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

2.11e-0579611216IPR015880
DomainZnf_C2H2

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF608 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

2.42e-0580511216IPR007087
DomainZnF_C2H2

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF608 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

2.54e-0580811216SM00355
DomainKRAB

ZNF266 ZNF473 ZNF805 ZNF226 ZNF517 ZNF718 ZNF425 ZNF480 ZNF264 ZNF81

5.91e-0535811210PS50805
DomainG_DYNAMIN_dom

MFN1 EHD4 EHD2

7.28e-05141123IPR030381
DomainG_DYNAMIN_2

MFN1 EHD4 EHD2

7.28e-05141123PS51718
DomainKRAB

ZNF266 ZNF473 ZNF805 ZNF226 ZNF517 ZNF718 ZNF425 ZNF480 ZNF264 ZNF81

7.60e-0536911210SM00349
DomainKRAB

ZNF266 ZNF473 ZNF805 ZNF226 ZNF517 ZNF718 ZNF425 ZNF480 ZNF264 ZNF81

7.77e-0537011210IPR001909
DomainDynamin_GTPase

MFN1 EHD4 EHD2

9.06e-05151123IPR001401
DomainDynamin_N

MFN1 EHD4 EHD2

9.06e-05151123PF00350
DomainDynamin_SF

MFN1 EHD4 EHD2

9.06e-05151123IPR022812
DomainATP-gua_PtransN

CKB CKM

2.12e-0441122PF02807
DomainPHOSPHAGEN_KINASE

CKB CKM

2.12e-0441122PS00112
DomainATP-guanido_PTrfase_N

CKB CKM

2.12e-0441122IPR022413
DomainATP-guanido_PTrfase_AS

CKB CKM

2.12e-0441122IPR022415
DomainATP-guanido_PTrfase_cat

CKB CKM

2.12e-0441122IPR022414
DomainATP-gua_Ptrans

CKB CKM

2.12e-0441122PF00217
Domain-

CKB CKM

2.12e-04411221.10.135.10
DomainPHOSPHAGEN_KINASE_N

CKB CKM

2.12e-0441122PS51509
DomainPHOSPHAGEN_KINASE_C

CKB CKM

2.12e-0441122PS51510
DomainKRAB

ZNF473 ZNF805 ZNF226 ZNF517 ZNF718 ZNF425 ZNF480 ZNF264 ZNF81

3.06e-043581129PF01352
DomainATP-guanido_PTrfase

CKB CKM

3.52e-0451122IPR000749
DomainEHD_N

EHD4 EHD2

3.52e-0451122IPR031692
DomainEHD_N

EHD4 EHD2

3.52e-0451122PF16880
DomainGln_synth/guanido_kin_cat_dom

CKB CKM

5.26e-0461122IPR014746
Domain-

CKB CKM

5.26e-04611223.30.590.10
DomainLiprin

PPFIA2 PPFIA3

5.26e-0461122IPR029515
DomainTransl_elong_EFTu/EF1A_C

GSPT1 GSPT2

9.75e-0481122IPR004160
DomainGTP_EFTU_D3

GSPT1 GSPT2

9.75e-0481122PF03143
DomainG_TR_CS

GSPT1 GSPT2

1.25e-0391122IPR031157
DomainTransl_elong_EF1A/Init_IF2_C

GSPT1 GSPT2

1.55e-03101122IPR009001
DomainEF-hand_4

EHD4 EHD2

1.55e-03101122PF12763
DomainEH

EHD4 EHD2

1.89e-03111122PS50031
DomainEH

EHD4 EHD2

1.89e-03111122SM00027
DomainEH_dom

EHD4 EHD2

1.89e-03111122IPR000261
DomainSAM_2

SAMD9 PPFIA2 PPFIA3

2.18e-03431123PF07647
DomainG_TR_1

GSPT1 GSPT2

2.66e-03131122PS00301
Domainubiquitin

ANKUB1 ZFAND4 SACS

2.81e-03471123PF00240
Domainzf-C2H2_6

ZNF266 ZNF473 ZNF805 PRDM10 ZNF718 ZNF425 ZNF480

2.86e-033141127PF13912
DomainSET_dom

SETD2 PRDM10 SETD5

3.35e-03501123IPR001214
DomainSET

SETD2 PRDM10 SETD5

3.35e-03501123PS50280
DomainSulfatase_CS

ARSH SULF1

4.05e-03161122IPR024607
DomainSULFATASE_1

ARSH SULF1

4.57e-03171122PS00523
DomainSULFATASE_2

ARSH SULF1

4.57e-03171122PS00149
DomainP-loop_NTPase

SAMD9 RHOBTB3 NLRP2 MFN1 GSPT1 EHD4 EHD2 GSPT2 ABCA6 MYO3B KIFC3 RAD54L

4.88e-0384811212IPR027417
DomainUbiquitin_dom

ANKUB1 ZFAND4 SACS

5.10e-03581123IPR000626
DomainSulfatase

ARSH SULF1

5.12e-03181122PF00884
DomainEFTu-like_2

GSPT1 GSPT2

5.12e-03181122IPR004161
DomainSulfatase_N

ARSH SULF1

5.12e-03181122IPR000917
DomainGTP_EFTU_D2

GSPT1 GSPT2

5.12e-03181122PF03144
DomainG_TR_2

GSPT1 GSPT2

5.12e-03181122PS51722
DomainTF_GTP-bd_dom

GSPT1 GSPT2

5.70e-03191122IPR000795
PathwayREACTOME_EUKARYOTIC_TRANSLATION_TERMINATION

ETF1 GSPT1 GSPT2

3.75e-066823MM15419
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MRPS31 SYNE1 PPFIA2 MB TSC1 STOX1 FER1L6 GSPT1 EHD4 DST GSPT2 ZNF608 KIAA0825 SACS SETD5 CEBPZ NSA2 DGKK VPS35 PYCR2 PLXNA2

1.20e-0814421162135575683
Pubmed

Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1.

ETF1 GSPT1 GSPT2

3.62e-08311639712840
Pubmed

Structural insights into eRF3 and stop codon recognition by eRF1.

ETF1 GSPT1 GSPT2

1.44e-074116319417105
Pubmed

The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing.

PPFIA2 PPFIA3 GRIP1

3.60e-075116319013515
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCAPD3 WDR64 CALU BARD1 PPFIA3 ZFAND4 FER1L6 CEP350 NSA2 ZNF516 KDM2B PYCR2

1.59e-066381161231182584
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MRPS31 NCAPD3 CALU SYNE1 ETF1 NUP88 NOL9 NSUN2 GSPT1 EHD4 CKB WDR3 TM9SF2 CEBPZ PRIM1 VPS35 PYCR2

5.18e-0614251161730948266
Pubmed

Myocardial creatine kinase expression after left ventricular assist device support.

CKB CKM

1.10e-052116212039490
Pubmed

Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation.

GSPT1 GSPT2

1.10e-052116215987998
Pubmed

Creatine kinase transcript accumulation: effect of nerve during muscle development.

CKB CKM

1.10e-052116210417818
Pubmed

Setd5, but not Setd2, is indispensable for retinal cell survival and proliferation.

SETD2 SETD5

1.10e-052116236349512
Pubmed

Creatine kinase activity in normal and Duchenne muscular dystrophy fibroblasts.

CKB CKM

1.10e-05211627057800
Pubmed

Developmental anomalies and neoplasia in animals and cells deficient in the large zinc finger protein KRC.

RAG2 HIVEP3

1.10e-052116212378523
Pubmed

PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure.

PPFIA2 PPFIA3

1.10e-052116234031393
Pubmed

Structure of the mammalian ribosomal pre-termination complex associated with eRF1.eRF3.GDPNP.

ETF1 GSPT1

1.10e-052116224335085
Pubmed

In vitro reconstitution of eukaryotic translation reveals cooperativity between release factors eRF1 and eRF3.

ETF1 GSPT1

1.10e-052116216777602
Pubmed

The effects of prior calcium channel blocker therapy on creatine kinase-MB levels after percutaneous coronary interventions.

CKB CKM

1.10e-052116219337554
Pubmed

Dissimilarity in the folding of human cytosolic creatine kinase isoenzymes.

CKB CKM

1.10e-052116221931810
Pubmed

The niche component periostin is produced by cancer-associated fibroblasts, supporting growth of gastric cancer through ERK activation.

RAG2 POSTN

1.10e-052116224418260
Pubmed

Subunit conformation and dynamics in a heterodimeric protein: studies of the hybrid isozyme of creatine kinase.

CKB CKM

1.10e-05211629748661
Pubmed

C-terminal domains of human translation termination factors eRF1 and eRF3 mediate their in vivo interaction.

ETF1 GSPT1

1.10e-05211629928949
Pubmed

Exploring the role of the active site cysteine in human muscle creatine kinase.

CKB CKM

1.10e-052116216981706
Pubmed

Creatine kinase in non-muscle tissues and cells.

CKB CKM

1.10e-05211627808454
Pubmed

Approaching the multifaceted nature of energy metabolism: inactivation of the cytosolic creatine kinases via homologous recombination in mouse embryonic stem cells.

CKB CKM

1.10e-05211627808458
Pubmed

Diagnostic significance of total creatine kinase and its isoform in tubal ectopic pregnancy.

CKB CKM

1.10e-052116223876027
Pubmed

The effect of eukaryotic release factor depletion on translation termination in human cell lines.

ETF1 GSPT1

1.10e-052116215326224
Pubmed

Cryo-EM structure of the mammalian eukaryotic release factor eRF1-eRF3-associated termination complex.

ETF1 GSPT1

1.10e-052116223091004
Pubmed

Role of MKK3-p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice.

LEPR MAP2K3

1.10e-052116219066844
Pubmed

Functional role of Tia1/Pub1 and Sup35 prion domains: directing protein synthesis machinery to the tubulin cytoskeleton.

GSPT1 GSPT2

1.10e-052116224981173
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NCAPD3 RHOBTB3 HIP1R XPO4 DST ATP11B ZNF608 SULF1 ZNF516 KDM2B

1.18e-055291161014621295
Pubmed

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.

ETF1 GSPT1 GSPT2

1.28e-0514116316452507
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

MRPS31 NCAPD3 CALU XPO4 NSUN2 GSPT1 EHD4 EHD2 CKB WDR3 DST CEBPZ NSA2 VPS35 PYCR2 EXOC7

2.41e-0514401161630833792
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNE1 XPO4 SETD2 SETD5 EEPD1

2.44e-05102116511214970
Pubmed

Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells.

ETF1 GSPT1

3.30e-053116235763353
Pubmed

Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses.

PPFIA2 PPFIA3

3.30e-053116229439199
Pubmed

Silencing of adaptor protein SH3BP2 reduces KIT/PDGFRA receptors expression and impairs gastrointestinal stromal tumors growth.

PDGFRA SH3BP2

3.30e-053116229885053
Pubmed

CD5 dynamically calibrates basal NF-κB signaling in T cells during thymic development and peripheral activation.

RAG2 THEMIS

3.30e-053116232513716
Pubmed

Diabetes Induces Cardiac Fibroblast Activation, Promoting a Matrix-Preserving Nonmyofibroblast Phenotype, Without Stimulating Pericyte to Fibroblast Conversion.

PDGFRA LEPR

3.30e-053116236892073
Pubmed

Polypeptide chain release factor eRF3 is a novel molecular partner of survivin.

GSPT1 GSPT2

3.30e-053116223377885
Pubmed

Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation.

RAG2 LEPR

3.30e-053116212438645
Pubmed

The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs.

ETF1 GSPT1

3.30e-05311629620853
Pubmed

Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor of Programmed -1 Ribosomal Frameshifting.

ETF1 GSPT1

3.30e-053116230682371
Pubmed

Predictive value of cardiac troponin-I compared to creatine kinase-myocardial band for the assessment of infarct size as measured by cardiac magnetic resonance.

CKB CKM

3.30e-053116220588136
Pubmed

A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression.

RAG2 PDGFRA

3.30e-053116229725010
Pubmed

Intestinal mTOR regulates GLP-1 production in mouse L cells.

TSC1 LEPR

3.30e-053116226037201
Pubmed

EHD Proteins Cooperate to Generate Caveolar Clusters and to Maintain Caveolae during Repeated Mechanical Stress.

EHD4 EHD2

3.30e-053116228943089
Pubmed

Receptor for advanced glycation end products aggravates cognitive deficits in type 2 diabetes through binding of C-terminal AAs 2-5 to mitogen-activated protein kinase kinase 3 (MKK3) and facilitation of MEKK3-MKK3-p38 module assembly.

LEPR MAP2K3

3.30e-053116235080104
Pubmed

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.

TSC1 LEPR

3.30e-053116221606597
Pubmed

Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro.

CKB CKM

3.30e-053116228806770
Pubmed

The processed isoform of the translation termination factor eRF3 localizes to the nucleus to interact with the ARF tumor suppressor.

GSPT1 GSPT2

3.30e-053116224569073
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MBTPS1 HYKK PPFIA2 SH3BP2 BARD1 FRYL WDR25 ZNF462 HIVEP3 ATP11B ZNF608 ZNF718 SETD5 EEPD1 RAPGEF2 MAP2K3

3.60e-0514891161628611215
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF473 CEP350 ZNF462 HIVEP3 SETD2 VPS13D SACS EEPD1 EXOC7

4.29e-05493116915368895
Pubmed

Apocrine glands are bystanders in hidradenitis suppurativa and their involvement is gender specific.

SYNE1 XPO4 ATP11B SULF1

4.64e-0559116432031713
Pubmed

Systematic dissection of coordinated stromal remodeling identifies Sox10+ glial cells as a therapeutic target in myelofibrosis.

PDGFRA LEPR

6.59e-054116237267917
Pubmed

C-terminal EH-domain-containing proteins: consensus for a role in endocytic trafficking, EH?

EHD4 EHD2

6.59e-054116216155252
Pubmed

Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection.

RAG2 THEMIS

6.59e-054116219597497
Pubmed

Calumenin, a Ca2+-binding protein retained in the endoplasmic reticulum with a novel carboxyl-terminal sequence, HDEF.

CALU CKM

6.59e-05411629218460
Pubmed

Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis.

RAG2 POSTN

6.59e-054116227905395
Pubmed

Resident fibroblast expansion during cardiac growth and remodeling.

PDGFRA POSTN

6.59e-054116229158033
Pubmed

HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1.

ETF1 GSPT1

6.59e-054116218539146
Pubmed

Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα.

LEPR POSTN

6.59e-054116225003192
Pubmed

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.

PDGFRA LEPR

6.59e-054116235614212
Pubmed

Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans.

EHD4 EHD2

6.59e-054116217233914
Pubmed

EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.

EHD4 EHD2

6.59e-054116210673336
Pubmed

Leptin is a physiological regulator of skeletal muscle angiogenesis and is locally produced by PDGFRα and PDGFRβ expressing perivascular cells.

PDGFRA LEPR

6.59e-054116230121753
Pubmed

Role of serum myeloperoxidase, CPK, CK-MB, and cTnI tests in early diagnosis of myocardial ischemia during ERCP.

CKB CKM

6.59e-054116225141318
Pubmed

The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis.

RAG2 HIVEP3

6.59e-054116221390242
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

MRPS31 BARD1 NOL9 CEP350 SETD2 PRDM10 CEBPZ HECA

8.21e-05417116836537216
Pubmed

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification.

RAG2 RAD54L

1.10e-045116212186839
Pubmed

Regional specialization and fate specification of bone stromal cells in skeletal development.

PDGFRA LEPR

1.10e-045116234260921
Pubmed

EH domain proteins regulate cardiac membrane protein targeting.

EHD4 EHD2

1.10e-045116220489164
Pubmed

Cardiovascular disease testing on the Dimension Vista system: biomarkers of acute coronary syndromes.

MB CKM

1.10e-045116219523464
Pubmed

Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury.

PDGFRA POSTN

1.10e-045116238469561
Pubmed

SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition.

TSC1 LEPR

1.10e-045116232726607
Pubmed

Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase.

CKB CKM

1.10e-04511622914937
Pubmed

A THEMIS:SHP1 complex promotes T-cell survival.

RAG2 THEMIS

1.10e-045116225535246
Pubmed

Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium.

RAG2 TSC1

1.10e-045116231292548
Pubmed

A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay.

ETF1 GSPT2

1.10e-045116218447585
Pubmed

Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase.

GSPT1 GSPT2

1.10e-045116214685257
Pubmed

Developmental regulation of creatine kinase gene expression by myogenic factors in embryonic mouse and chick skeletal muscle.

CKB CKM

1.10e-04511621668275
Pubmed

Mutation in the Trapalpha/Ssr1 gene, encoding translocon-associated protein alpha, results in outflow tract morphogenetic defects.

POSTN PLXNA2

1.10e-045116217015483
Pubmed

Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle.

PDGFRA LEPR

1.10e-045116235029658
Pubmed

PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion.

PDGFRA LEPR

1.10e-045116223776077
Pubmed

Leptin-receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis.

PDGFRA LEPR

1.10e-045116228481328
Pubmed

Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.

ETF1 NSUN2 EHD4 CEBPZ PRIM1 PYCR2 MAP2K3

1.10e-04323116724797263
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

MRPS31 PDGFRA EHD4 EHD2 NSA2 SULF1

1.21e-04228116630471916
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

SYNE1 PPFIA2 FRYL DST EXOC7

1.57e-04151116517043677
Pubmed

Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life.

LEPR POSTN

1.64e-046116231320650
Pubmed

Mechanisms promoting translocations in editing and switching peripheral B cells.

RAG2 SH3BP2

1.64e-046116219587764
Pubmed

Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.

ETF1 GSPT1

1.64e-046116227863242
Pubmed

Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins.

PPFIA2 PPFIA3

1.64e-046116221618221
Pubmed

The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.

GSPT1 GSPT2

1.64e-046116210358005
Pubmed

DHHC protein family targets different subsets of glioma stem cells in specific niches.

ETF1 GSPT2 VPS35

1.83e-0433116330658672
Pubmed

Molecular characterization of a testis-specific estrogen sulfotransferase and aberrant liver expression in obese and diabetogenic C57BL/KsJ-db/db mice.

RAG2 LEPR

2.29e-04711627750469
Pubmed

Creatine and creatinine metabolism.

CKB CKM

2.29e-047116210893433
Pubmed

Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing.

PDGFRA POSTN

2.29e-047116235977484
Pubmed

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways.

ETF1 GSPT1

2.29e-047116218256688
Pubmed

Preexisting endothelial cells mediate cardiac neovascularization after injury.

PDGFRA POSTN

2.29e-047116228650345
Pubmed

The DNA sequence and analysis of human chromosome 13.

MRPS31 XPO4 POSTN TM9SF2 SACS

2.72e-04170116515057823
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NUP88 FRYL NOL9 NSUN2 CKB WDR3 DST CEBPZ NSA2

3.52e-04653116922586326
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZNF473 SYNE1 RHOBTB3 NSUN2 CEP350 WDR3 DST SACS SULF1 KIFC3 RAPGEF2 EXOC7 CRTAP

3.65e-0412851161335914814
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF266 ZNF473 ZNF805 ZNF226 ZNF462 HIVEP3 PRDM10 ZNF608 ZNF517 ZNF718 ZNF425 ZNF516 ZNF480 ZNF264 ZNF81 ZNF653

1.67e-08718721628
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

RHOBTB3 BARD1 BEST3 GRIP1 POSTN TGFBR3 SULF1 MYO3B

5.58e-0820011684a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1|Neuronal / cells hierarchy compared to all cells using T-Statistic

RHOBTB3 BARD1 BEST3 GRIP1 POSTN TGFBR3 SULF1 MYO3B

5.58e-082001168fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

RHOBTB3 BARD1 BEST3 GRIP1 POSTN TGFBR3 SULF1 MYO3B

5.58e-082001168c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NUSAP1 NCAPD3 BARD1 AGBL3 SASS6 CDT1 RAD54L

4.89e-071811167e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

DOK6 PDGFRA PPFIA2 LEPR TGFBR3 DST ABCA6

6.09e-071871167bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

DOK6 PDGFRA PPFIA2 POSTN TGFBR3 DST ABCA6

7.53e-071931167e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

NUSAP1 NCAPD3 BARD1 PRIM1 SASS6 CDT1 RAD54L

7.80e-071941167a12b64945e10f00aa983678a02586c59badc1570
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NUSAP1 NCAPD3 BARD1 PRIM1 SASS6 CDT1 RAD54L

8.35e-0719611679591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

LEPR EHD2 CKB TGFBR3 EEPD1 PLXNA2 CRTAP

8.64e-071971167434ae0231972acba12d06279908cf407e70511ac
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

NUSAP1 NCAPD3 BARD1 PRIM1 SASS6 CDT1 RAD54L

9.24e-07199116788d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCellfacs-Trachea-nan-3m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTPS1 PDGFRA CALU EHD2 TGFBR3 TM9SF2 CRTAP

9.24e-07199116767f78c070c56e44fba36542041bf7fa1c291807c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTPS1 PDGFRA CALU EHD2 TGFBR3 TM9SF2 CRTAP

9.24e-0719911671ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCellBiopsy_Other_PF-Immune-Proliferating_Macrophages|Biopsy_Other_PF / Sample group, Lineage and Cell type

NUSAP1 NCAPD3 BARD1 PRIM1 SASS6 CDT1 RAD54L

9.56e-07200116761473e8613f39a92002d5b631e6bd563735566e4
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUSAP1 THEMIS MB INPP4B PRIM1 CDT1

3.82e-061591166a5509f0604ef0caef5ed1af83dd89c86686c73cc
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

THEMIS SAMD9 ZNF266 ANKUB1 SYNE1 TGFBR3

5.24e-061681166b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUSAP1 NCAPD3 EHD4 PRIM1 CDT1 RAD54L

6.40e-061741166c988471207ba06195bc3e41056435e8c31c20bbe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRA SYNE1 DAPK2 ZNF805 POSTN SP140L

6.62e-06175116612f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 BARD1 WDR25 INPP4B TSTD2 RAD54L

7.77e-06180116687347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RHOBTB3 BARD1 BEST3 GRIP1 POSTN SULF1

8.02e-061811166bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 RHOBTB3 HIVEP3 DST EEPD1 MYO3B

8.28e-061821166a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

DOK6 KANSL1L SLC3A1 AGBL3 GRIP1 ZNF462

8.81e-06184116651ed1ebfdef45149541917c66cbacad87072e51f
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRA CALU RHOBTB3 POSTN SULF1 CRTAP

9.37e-061861166360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 HIVEP3 DST ABCA6 EEPD1 MYO3B

9.66e-06187116677886f99c229610abd28c4c370d2c7d1536c9782
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|World / Stress and Cell class

CALU LEPR EHD2 TGFBR3 EEPD1 CRTAP

1.16e-051931166f31398dad5321a7bcb27e208bd73630e9756e897
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NUSAP1 NCAPD3 BARD1 PRIM1 CDT1 RAD54L

1.16e-051931166e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MB NXPE1 FRYL FER1L6 FSIP2 DST

1.19e-05194116649cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MB NXPE1 FRYL FER1L6 FSIP2 DST

1.19e-051941166fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRA INPP4B DST ABCA6 SULF1 EEPD1

1.19e-05194116690efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFRA INPP4B DST ABCA6 SULF1 EEPD1

1.19e-051941166df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRA LEPR TGFBR3 DST ABCA6 SULF1

1.23e-051951166f54bc4454270ff06e85596f98199372b50d0179f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NUSAP1 NCAPD3 BARD1 TGFBR3 PRIM1 CDT1

1.23e-051951166be8db0a22ef8ce24819f790b0bd93670e73af76f
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

NUSAP1 NCAPD3 THEMIS BARD1 CDT1 RAD54L

1.23e-0519511667e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell(2)_5-FU|World / Stress and Cell class

CALU EHD2 CKB TGFBR3 PLXNA2 CRTAP

1.23e-051951166e5b1d96fafeb2f3b1f4cdf6b2c9eddef36bca7ff
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

KANSL1L ANKUB1 DAPK2 HIVEP3 FARS2 RAPGEF2

1.26e-051961166ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALU ETF1 TGFBR3 TM9SF2 SULF1 MAP2K3

1.26e-05196116666d76249bd2770cdddff2c1fe59a016e95da2124
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALU ETF1 TGFBR3 TM9SF2 SULF1 MAP2K3

1.26e-0519611669bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOK6 SYNE1 POSTN TGFBR3 ABCA6 SULF1

1.30e-0519711660dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

DOK6 PDGFRA POSTN DST ABCA6 SULF1

1.30e-051971166f1c8936986123a3151140c374fcd62d6705c530b
ToppCellfacs-Trachea-3m|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MBTPS1 CALU EHD2 TGFBR3 DST TM9SF2

1.30e-051971166e77016d64b1cac9825fec7cfe5071f1567401187
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPFIA2 RHOBTB3 EHD2 POSTN SULF1 CRTAP

1.30e-051971166236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCellfacs-Trachea-nan-3m|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTPS1 CALU EHD2 TGFBR3 DST TM9SF2

1.30e-0519711660353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

DOK6 PDGFRA POSTN DST ABCA6 SULF1

1.30e-051971166fb847f2277609c31fffcdf49517243ce0684facf
ToppCellfacs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTPS1 CALU EHD2 DST TM9SF2 VPS35

1.34e-05198116622559b161e67b49fe8028bfaf861e069063599f5
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRA CALU EHD2 POSTN SULF1 CRTAP

1.34e-05198116675d104eead681f6bf47c4dd24913cc768c9a1717
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PDGFRA RHOBTB3 EHD2 TGFBR3 DST SULF1

1.38e-05199116640de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PDGFRA SYNE1 CKB POSTN TGFBR3 DST

1.38e-051991166e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PDGFRA LEPR EHD2 POSTN TGFBR3 SULF1

1.38e-0519911666200618e029063486719479c41eaf31798bd13cf
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRA CALU EHD2 POSTN SULF1 CRTAP

1.38e-0519911663d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDGFRA SYNE1 RHOBTB3 POSTN TGFBR3 GSPT2

1.38e-0519911666b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellDividing_Macrophages|World / lung cells shred on cell class, cell subclass, sample id

NUSAP1 NCAPD3 BARD1 EEPD1 PRIM1 CDT1

1.38e-0519911665c755b6876e164dc847ef7c723f850f227cf3a87
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NUSAP1 NCAPD3 BARD1 SASS6 CDT1 RAD54L

1.38e-051991166be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PPFIA2 RHOBTB3 INPP4B TGFBR3 ABCA6 SULF1

1.38e-051991166abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCellILEUM-non-inflamed-(8)_Fibroblast|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDGFRA RHOBTB3 EHD2 DST ABCA6 SULF1

1.38e-0519911666a0df9a2f30480043f9c1d7fbdede17eb0910cac
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDGFRA GRIP1 ZNF462 ZNF608 SULF1 EEPD1

1.41e-052001166ca5401b76ab014080914bf78042d368cf318effa
ToppCelldistal-Hematologic-Proliferating_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NUSAP1 NCAPD3 BARD1 PRIM1 CDT1 RAD54L

1.41e-0520011663835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

NUSAP1 NCAPD3 BARD1 SASS6 CDT1 RAD54L

1.41e-0520011669bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellBiopsy_Control_(H.)-Immune-Proliferating_Macrophages|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NUSAP1 BARD1 EEPD1 PRIM1 CDT1 RAD54L

1.41e-052001166ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCellLAM-Myeloid-pMacrophage|Myeloid / Condition, Lineage and Cell class

NUSAP1 BARD1 PRIM1 SASS6 CDT1 RAD54L

1.41e-0520011660078d56337d44074326e8ccd1d412d098d86eeab
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDGFRA GRIP1 ZNF462 ZNF608 SULF1 EEPD1

1.41e-05200116670c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRA SYNE1 LEPR TGFBR3 ABCA6 SULF1

1.41e-052001166b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCelldistal-Hematologic-Proliferating_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NUSAP1 NCAPD3 BARD1 PRIM1 CDT1 RAD54L

1.41e-0520011669c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDGFRA GRIP1 ZNF462 ZNF608 SULF1 EEPD1

1.41e-05200116640286010bd17cf9e34ecd5440953b072ebfae208
ToppCellLAM-Myeloid-pMacrophage|LAM / Condition, Lineage and Cell class

NUSAP1 BARD1 PRIM1 SASS6 CDT1 RAD54L

1.41e-0520011667e233d037165c9d3607604aaaf0f368e266567d3
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDGFRA SYNE1 CKB POSTN TGFBR3 DST

1.41e-05200116608bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

PDGFRA SYNE1 CKB POSTN TGFBR3 DST

1.41e-05200116602cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCelldistal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NUSAP1 NCAPD3 BARD1 PRIM1 CDT1 RAD54L

1.41e-0520011661b65c97e8123d0572d31525d6a10bc7f16857959
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFRA SYNE1 LEPR TGFBR3 ABCA6 SULF1

1.41e-0520011660c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellmild-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NUSAP1 NCAPD3 BARD1 TGFBR3 CDT1 RAD54L

1.41e-05200116663cc57b9331459efbb73051d174d198a3568b938
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZNF473 BEST3 DGKK MYO3B

3.01e-05681164cfd75c373e10b3761666ccd445ba74755efeb95f
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZNF473 BEST3 DGKK MYO3B

3.01e-05681164c25fb921dc83eecdc337353894829ae6b5192353
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZNF473 BEST3 DGKK MYO3B

3.01e-05681164712f5f4d3a1e0c0db1a340332876206b93bdac31
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

SAMD9 CCDC110 INPP4B AGBL3 POSTN

5.70e-0515711652c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 BARD1 CDT1 RAPGEF2 RAD54L

5.87e-051581165ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 HIVEP3 DST EEPD1 MYO3B

6.61e-051621165373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NUSAP1 STOX1 FER1L6 LRRC42 CDT1

6.81e-051631165360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NUSAP1 STOX1 FER1L6 LRRC42 CDT1

6.81e-051631165b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 WDR64 BARD1 ATP11B CDT1

7.63e-051671165bad33497ceeab968a7eb8a48b921c6f936390743
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENTPD7 HYKK MFN1 CKB KIFC3

7.85e-051681165de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 HYKK STOX1 LEPR ABCA6

8.07e-051691165849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NUSAP1 NCAPD3 BARD1 CDT1 RAD54L

8.07e-051691165e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

PDGFRA DAPK2 LEPR TGFBR3 ABCA6

8.07e-05169116584b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NUSAP1 BARD1 INPP4B SULF1 RAD54L

8.53e-051711165b0373ed8283ee1792b6a490bff93906546978593
ToppCellMyeloid-Myeloid-D_(Mast_cell)|Myeloid / shred on cell class and cell subclass (v4)

SYNE1 DAPK2 INPP4B CRTAP TPH1

8.53e-0517111655f1aafc4c55a9c6c3153430186a8a351425a3cb9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NUSAP1 BARD1 INPP4B SULF1 RAD54L

8.53e-051711165b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NUSAP1 NCAPD3 BARD1 SACS CDT1

9.01e-05173116520889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NUSAP1 NCAPD3 BARD1 SACS CDT1

9.01e-05173116546e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUSAP1 NCAPD3 EHD4 PRIM1 CDT1

9.26e-05174116566555c610251ea04f968c258e312d720c18e7cde
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA SYNE1 LEPR TGFBR3 ZNF516

9.51e-0517511651d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MB NSUN2 ZFAND4 DST SASS6

9.51e-051751165334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA SYNE1 LEPR TGFBR3 ZNF516

9.51e-051751165427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MB NSUN2 ZFAND4 DST SASS6

9.51e-051751165da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NUSAP1 ZNF473 DAPK2 CKM PRIM1

9.77e-051761165b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 PDGFRA HYKK LEPR ABCA6

9.77e-051761165fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK6 PDGFRA HYKK LEPR ABCA6

9.77e-051761165f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

ENTPD7 DOK6 MBTPS1 MFN1 DST

9.77e-0517611653de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

ENTPD7 DOK6 MBTPS1 MFN1 DST

1.00e-04177116582fdd6185b368f54f03de389427cbe3071d21a99
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 THEMIS BARD1 PRIM1 CDT1

1.03e-04178116579823d13652177de852c2acce9159049241f1d86
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NUSAP1 NCAPD3 BARD1 CDT1 RAD54L

1.09e-041801165f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LEPR CKM POSTN PRIM1 RAD54L

1.11e-041811165274c0b768925cd5804483303f8c5ebd17a534c41
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOK6 BEST3 FSIP2 POSTN DST

1.11e-04181116540df0afcb6848202da54670e84f22d7c3a515d01
DiseaseAutosomal Recessive Primary Microcephaly

NCAPD3 SASS6 PYCR2

7.37e-05221103C3711387
Diseasequinate measurement

LEPR EEPD1

1.40e-03151102EFO_0021167
Diseaseobsolete_red blood cell distribution width

SAMD9 HIP1R NOL9 ZFAND4 INPP4B ATP11B ABCA6 FARS2 EEPD1 PRIM1 ZNF516 KDM2B CDT1

1.53e-03134711013EFO_0005192
Diseaseresponse to acetylsalicylate

DOK6 SETD2

1.60e-03161102GO_1903492
DiseaseFamilial Progressive Myoclonic Epilepsy

TSC1 SACS

1.81e-03171102C0751777
DiseaseAtypical Inclusion-Body Disease

TSC1 SACS

1.81e-03171102C0751776
DiseaseMyoclonic Epilepsies, Progressive

TSC1 SACS

1.81e-03171102C0751778
DiseaseBiotin-Responsive Encephalopathy

TSC1 SACS

1.81e-03171102C0751780
DiseaseMay-White Syndrome

TSC1 SACS

1.81e-03171102C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

TSC1 SACS

1.81e-03171102C0751781
DiseaseAction Myoclonus-Renal Failure Syndrome

TSC1 SACS

2.03e-03181102C0751779
Diseasetreatment resistant depression, response to antidepressant

WDR64 HIVEP3

2.76e-03211102EFO_0009854, GO_0036276
DiseaseBREAST CANCER

BARD1 RAD54L

2.76e-03211102114480
DiseaseParoxysmal atrial fibrillation

CALU HIP1R BEST3 ZNF462

2.81e-031561104C0235480
Diseasefamilial atrial fibrillation

CALU HIP1R BEST3 ZNF462

2.81e-031561104C3468561
DiseasePersistent atrial fibrillation

CALU HIP1R BEST3 ZNF462

2.81e-031561104C2585653
DiseaseAtrial Fibrillation

CALU HIP1R BEST3 ZNF462

3.08e-031601104C0004238
Diseasesusceptibility to scarlet fever measurement

PPFIA2 MB FRYL

3.24e-03791103EFO_0008409

Protein segments in the cluster

PeptideGeneStartEntry
DERKLFNHLKSPHLK

BEST3

166

Q8N1M1
IPTEDLHHNLKSKIK

AGBL3

781

Q8NEM8
SFLHVHTPLISKKKF

ARSH

266

Q5FYA8
GTFKHHPKDNLIKLV

BARD1

681

Q99728
HDFTKFHSLKPKLLE

EHD2

366

Q9NZN4
FITHHIPDAKLKTEN

ABCA6

726

Q8N139
NNVFPFKIIHISKKH

SH3BP2

91

P78314
VKEHHKAFLASLSPA

CDT1

306

Q9H211
VEFHSNKKRKLTPDH

C1orf131

131

Q8NDD1
FALSKPTEKKDRVHH

CALU

16

O43852
LRKEKFHHLIPAHTF

EEPD1

461

Q7L9B9
LRFKKAHVTHPELKA

NSA2

176

O95478
FHLDVKHNHVKLKPT

RAG2

46

P55895
ILGTAHEFKKHFELP

RAD54L

346

Q92698
EKHFFHKVNERLSKP

MFN1

216

Q8IWA4
LRKSPHLEKFHQFLV

NSUN2

136

Q08J23
DSFLSHHPEKPKKEL

PDGFRA

691

P16234
IHALHYSQPEKSKKE

NOL9

176

Q5SY16
DHLHFTPESIRFKEK

DGKK

841

Q5KSL6
DVPLHFHFETLLKKT

KANSL1L

641

A0AUZ9
KLLNPHQHTDDKIFK

KIAA0825

711

Q8IV33
LSEKHPHFKNVKERT

MBTPS1

221

Q14703
LLSFAAAHVPVKKHK

ENTPD7

151

Q9NQZ7
EFLKNAIHLEPHKKA

HECA

296

Q9UBI9
HIKLPNLGKHEKFSE

CKB

296

P12277
LAVSHEEFLHKLKSF

DST

3511

Q03001
EVLKALKSLFEHHKA

PPFIA3

151

O75145
SFHIPKELISLHIKE

INPP4B

261

O15327
FLSKLLSIFPKVHKE

FSIP2

6186

Q5CZC0
KHFTILDAPGHKSFV

GSPT2

281

Q8IYD1
FILVEPSHKKEHYLS

PLXNA2

146

O75051
KTEQHSHPFVKKAFR

FAM157A

106

C9JC47
PLVHEVLNLAFKHFK

FRYL

146

O94915
QLLSKLDHPAIVKFH

NEK11

81

Q8NG66
KPETFEHLFIKHTAS

LEPR

891

P48357
FTKFHSLKPKLIEAV

EHD4

371

Q9H223
LVHSKVPLKEFDHSN

LRRC42

286

Q9Y546
TTFSLAHELQKIPHK

NLRP2

31

Q9NX02
PDFIQVKKHVRSFHS

PRDM10

626

Q9NQV6
TTPNFKKLHEAHFKE

NUSAP1

181

Q9BXS6
KKHFTILDAPGHKSF

GSPT1

151

P15170
LLADIIPEHHQKKTF

EXOC7

381

Q9UPT5
KAHKYNLKVTFHIEP

MANEA

211

Q5SRI9
KVHLSEKIHPFIRKS

PRIM1

201

P49642
RKTEQHSHPFVKKAF

FAM157B

106

P0CG42
LLLTKISFHLKHPQF

HIP1R

136

O75146
AAKLDKTLQRFHHPK

HYKK

151

A2RU49
LEFSHTKLEHLVKRP

KDM2B

176

Q8NHM5
LPRETKKHAVAIIFH

DOK6

71

Q6PKX4
HTKKIAHFDLKPENI

DAPK2

141

Q9UIK4
LPKAIAAAHTFLLKH

CRTAP

161

O75718
LHKDFESILPTRKNH

CEP350

771

Q5VT06
TFHVKLPKKHNVELG

GRIP1

571

Q9Y3R0
VETNPFKHLTHLSLK

SASS6

126

Q6UVJ0
FTKPSLSAVLKHFKI

SACS

1216

Q9NZJ4
LKKLSVHFHPSVALF

CEBPZ

716

Q03701
VEVLKALKSLFEHHK

PPFIA2

171

O75334
LKFFDLHETGIFKKH

NXPE1

371

Q8N323
LDIVDLLKKAKFHHS

RHOBTB3

531

O94955
KKLLHSFHSELPVLS

NUP88

641

Q99567
EHPFFTLHKTKKTDI

MAP2K3

321

P46734
LFDKIIKISVFHHKL

FER1L6

141

Q2WGJ9
HIFLEKHLESFPKQG

MRPS31

331

Q92665
TFKKKLSQSLPDHHE

SYNE1

7691

Q8NF91
HVKLAHLSKHPKFEE

CKM

296

P06732
HLSKHPKFEEILTRL

CKM

301

P06732
EVTKAESKFHHPVRL

RIPPLY1

86

Q0D2K3
HPDQTKHLDFLKEIK

SAMD9

421

Q5K651
DSIIHLLHKGKPVSF

KIFC3

476

Q9BVG8
HLHSSKEFVGKPTIL

SETD5

236

Q9C0A6
KLIIDFIPNHTSDKH

SLC3A1

206

Q07837
KHSDVLFLAVKPHII

PYCR2

61

Q96C36
DTVFKHFKRHKLEIS

SP140L

51

Q9H930
KLLPFRETVSKFHVH

CCDC110

321

Q8TBZ0
TPLTIVFKHKHKDCV

ANKUB1

276

A6NFN9
LSLEHQKFLKHKFLV

NCAPD3

431

P42695
LDIIKKVFDRHLHPT

ATP11B

1086

Q9Y2G3
KVFDRHLHPTSTEKA

ATP11B

1091

Q9Y2G3
QEKHSLPADFTKLHL

RAPGEF2

16

Q9Y4G8
EKEPLHVVATKAFHS

THEMIS

361

Q8N1K5
LKHALSGHAKVKPFD

TPH1

341

P17752
KKDLELHVHQAHKPF

ZNF516

186

Q92618
IEDSFHKLIPKGHEK

ZNF718

91

Q3SXZ3
EKLDSVKFHTLKSHP

ZNF653

596

Q96CK0
ALPKTAHHFVIRKTE

TSC1

611

Q92574
HAEHIFLSFRKSKSP

XPO4

36

Q9C0E2
SKIPFKILSGHEHAV

WDR88

91

Q6ZMY6
NILTVLKLKHFHPLF

VPS35

411

Q96QK1
VIPEVLRKSHSHFDK

STOX1

616

Q6ZVD7
SHKPEDTHTIKQKLA

HIVEP3

351

Q5T1R4
HLSPGEFHKEVEKFL

TSTD2

281

Q5T7W7
FLNKSAKHLSLHIVP

TRAV29DV5

91

P04437
KIHFKKHLLHVTSRP

SETD2

141

Q9BYW2
EIKPLAQSHATKHKI

MB

86

P02144
LTLHQKIHTKEKPFA

ZNF517

411

Q6ZMY9
LQIHQKAHSIEKPFK

ZNF226

546

Q9NYT6
DKPIKKQLGVSFHLH

ZNF480

121

Q8WV37
TFILHKRAHTGEKPF

ZNF264

441

O43296
VAAKLEPKSFKHTHI

TM9SF2

231

Q99805
SKDLPGHFLKDHLNK

ZNF608

846

Q9ULD9
KRHPSIKVTAEDFVH

ZNF462

1536

Q96JM2
ITTLKFHPKDHNIFL

WDR25

336

Q64LD2
KSFDLIHSPHGELKA

WDR3

366

Q9UNX4
PLSDSSKKIDFHLHV

ZFAND4

166

Q86XD8
HIFREIIKPAEKSLH

POSTN

486

Q15063
VDLIDKFVHPKTHKT

FARS2

396

O95363
FSLLQKVSPVAHKHL

TBC1D10A

246

Q9BXI6
ALKTHIAVHAKEKPS

ZNF425

736

Q6IV72
KQEKLKSHLHPFKEA

SULF1

691

Q8IWU6
TFILHKRAHTGEKPF

ZNF805

441

Q5CZA5
KTFTKPLAVIHHEAE

TGFBR3

746

Q03167
RSHFFAPQKIHTVEK

ZNF81

286

P51508
DLHPKHFKINDILFL

WDR64

696

B1ANS9
ASLIKLQSFHTKEHP

ZNF473

631

Q8WTR7
HINIFLVDKKHPEFS

VPS13D

1786

Q5THJ4
LTEHLKTHTAKDPFE

ZNF266

311

Q14584
REVLHKFTVDLPKKH

ETF1

166

P62495
IEHKLAFLRTHVPKD

LDAH

116

Q9H6V9
LHHQKKLSDFRLPEE

MYO3B

541

Q8WXR4