Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAAF5 DNAH5 DNAH11

5.00e-05371104GO:0045505
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH5 DNAH11

1.25e-04181103GO:0008569
GeneOntologyMolecularFunctionribonucleoprotein complex binding

RHBDD2 RICTOR DHX33 ERAL1 IFRD2 DNAJC1 SMG6

1.46e-042061107GO:0043021
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH5 DNAH11

4.82e-04281103GO:0051959
GeneOntologyMolecularFunctionribosome binding

RICTOR DHX33 ERAL1 IFRD2 DNAJC1

5.34e-041201105GO:0043022
GeneOntologyCellularComponentcell-cell junction

EPPK1 ASH1L OBSCN PTK2 ADD3 TWF1 KCNA5 TIAM1 SSX2IP TRPV4 PRKD1 PLCG1 SYMPK

1.39e-0559111013GO:0005911
GeneOntologyCellularComponentsupramolecular fiber

KNTC1 DNAH3 EPPK1 NEBL OBSCN TWF1 KCNA5 TIAM1 TTLL11 ASPM TRPV4 PRKD1 BCL10 YWHAQ DNAH5 KRT38 KRT37 DNAH11

4.19e-05117911018GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KNTC1 DNAH3 EPPK1 NEBL OBSCN TWF1 KCNA5 TIAM1 TTLL11 ASPM TRPV4 PRKD1 BCL10 YWHAQ DNAH5 KRT38 KRT37 DNAH11

4.57e-05118711018GO:0099081
GeneOntologyCellularComponentanchoring junction

EPPK1 RTN4 ASH1L OBSCN PTK2 ADD3 TWF1 FOCAD KCNA5 TIAM1 SSX2IP TRPV4 PRKD1 PLCG1 YWHAQ SYMPK

5.09e-0597611016GO:0070161
GeneOntologyCellularComponentdynein complex

DNAH3 ODAD1 DNAH5 DNAH11

1.87e-04541104GO:0030286
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KNTC1 DNAH3 EPPK1 TWF1 TIAM1 TTLL11 ASPM TRPV4 BCL10 YWHAQ DNAH5 KRT38 KRT37 DNAH11

2.65e-0489911014GO:0099513
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 ODAD1 DNAH5

3.00e-04251103GO:0005858
GeneOntologyCellularComponent9+0 motile cilium

DNAH5 DNAH11

4.06e-0461102GO:0097728
GeneOntologyCellularComponentmicrotubule

KNTC1 DNAH3 TIAM1 TTLL11 ASPM TRPV4 BCL10 YWHAQ DNAH5 DNAH11

5.12e-0453311010GO:0005874
GeneOntologyCellularComponentcilium

DNAH3 PRAMEF22 ODAD1 FUZ PTK2 DNAAF5 TIAM1 TTLL11 SSX2IP TRPV4 IFT122 DNAH5 DNAH11

8.77e-0489811013GO:0005929
GeneOntologyCellularComponentcell-cell contact zone

OBSCN PTK2 KCNA5 TIAM1

1.54e-03941104GO:0044291
HumanPhenoNasal polyposis

NEK10 ODAD1 DNAAF5 MIF DNAH5 DNAH11

1.71e-0574396HP:0100582
HumanPhenoAbnormal nasal mucosa morphology

NEK10 ODAD1 DNAAF5 MIF DNAH5 DNAH11

2.68e-0580396HP:0000433
HumanPhenoPeribronchovascular interstitial thickening

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

3.01e-0549395HP:0025177
HumanPhenoEctopic pregnancy

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

3.01e-0549395HP:0031456
HumanPhenoPulmonary situs ambiguus

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

3.01e-0549395HP:0011617
HumanPhenoAbnormal pulmonary situs morphology

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

3.01e-0549395HP:0011615
HumanPhenoLithoptysis

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

3.01e-0549395HP:0032543
HumanPhenoAnomalous pulmonary venous return

NEK10 ODAD1 DNAAF5 DNAH5 AFF4 DNAH11

3.31e-0583396HP:0010772
HumanPhenoAtrial situs ambiguous

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

3.33e-0550395HP:0011539
HumanPhenoTransposition of the great arteries

NEK10 ODAD1 DNAAF5 DNAH5 ATP2B1 DNAH11

3.79e-0585396HP:0001669
HumanPhenoAbnormal inferior vena cava morphology

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

4.43e-0553395HP:0025576
HumanPhenoAbnormal atrial arrangement

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

4.85e-0554395HP:0011535
HumanPhenoAbnormal pulmonary vein morphology

NEK10 ODAD1 DNAAF5 DNAH5 AFF4 DNAH11

4.93e-0589396HP:0030968
HumanPhenoAbnormality of the pulmonary veins

NEK10 ODAD1 DNAAF5 DNAH5 AFF4 DNAH11

4.93e-0589396HP:0011718
HumanPhenoAbnormal breath sound

NEK10 ODAD1 DNAAF5 TRPV4 ATP11A DNAH5 DNAH11

5.41e-05133397HP:0030829
HumanPhenoDecreased nasal nitric oxide

NEK10 DNAAF5 DNAH5 DNAH11

6.07e-0529394HP:0033036
HumanPhenoNasal congestion

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

8.11e-0560395HP:0001742
HumanPhenoCiliary dyskinesia

ODAD1 DNAAF5 DNAH5 DNAH11

9.05e-0532394HP:0012265
HumanPhenoRecurrent mycobacterial infections

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

9.50e-0562395HP:0011274
HumanPhenoWheezing

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

1.11e-0464395HP:0030828
HumanPhenoAbnormal ciliary motility

ODAD1 DNAAF5 DNAH5 DNAH11

1.15e-0434394HP:0012262
HumanPhenoPolysplenia

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

1.28e-0466395HP:0001748
HumanPhenoAbnormal respiratory motile cilium physiology

ODAD1 DNAAF5 DNAH5 DNAH11

1.45e-0436394HP:0012261
HumanPhenoRecurrent upper and lower respiratory tract infections

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

1.48e-0468395HP:0002873
HumanPhenoRecurrent sinopulmonary infections

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

1.48e-0468395HP:0005425
HumanPhenoProductive cough

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

1.48e-0468395HP:0031245
HumanPhenoAbnormal pulmonary thoracic imaging finding

NEK10 ODAD1 DNAAF5 ATP11A BCL10 DNAH5 DNAH11

1.55e-04157397HP:0031983
HumanPhenoChronic sinusitis

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

1.59e-0469395HP:0011109
HumanPhenoBroad distal phalanges of all fingers

IFT122 CHST3

1.71e-043392HP:0009880
HumanPhenoCough

NEK10 ODAD1 FOCAD DNAAF5 ATP11A DNAH5 DNAH11

1.74e-04160397HP:0012735
HumanPhenoChronic rhinitis

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

2.07e-0473395HP:0002257
HumanPhenoBronchiectasis

NEK10 ODAD1 DNAAF5 MIF ATP11A DNAH5 DNAH11

3.04e-04175397HP:0002110
HumanPhenoAtelectasis

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

3.19e-0480395HP:0100750
HumanPhenoPersistent left superior vena cava

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

3.79e-0483395HP:0005301
HumanPhenoPregnancy history

NEK10 ODAD1 ASH1L FUZ DNAAF5 DNAH5 DNAH11

3.86e-04182397HP:0002686
HumanPhenoPast medical history

NEK10 ODAD1 ASH1L FUZ DNAAF5 DNAH5 DNAH11

3.99e-04183397HP:0032443
HumanPhenoFemale infertility

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

4.01e-0484395HP:0008222
HumanPhenoAbnormal superior vena cava morphology

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

4.24e-0485395HP:0025575
HumanPhenoAbnormal vena cava morphology

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

4.97e-0488395HP:0030971
HumanPhenoAbnormal sputum

NEK10 ODAD1 DNAAF5 MIF DNAH5 DNAH11

5.12e-04136396HP:0032016
HumanPhenoAbnormal vena cava morphology

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

5.24e-0489395HP:0005345
HumanPhenoAirway obstruction

NEK10 ODAD1 DNAAF5 MIF DNAH5 DNAH11

5.33e-04137396HP:0006536
HumanPhenoAsplenia

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

5.81e-0491395HP:0001746
HumanPhenoDouble outlet right ventricle

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

6.74e-0494395HP:0001719
HumanPhenoCongenital malformation of the right heart

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

7.42e-0496395HP:0011723
HumanPhenoAbnormal fingertip morphology

EMC1 NEK10 ODAD1 DNAAF5 ATP11A DNAH5 DNAH11

7.46e-04203397HP:0001211
HumanPhenoAplasia/Hypoplasia of the spleen

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

8.15e-0498395HP:0010451
HumanPhenoFlattened epiphysis

TRPV4 IFT122 CHST3

8.49e-0425393HP:0003071
HumanPhenoClubbing

NEK10 ODAD1 DNAAF5 ATP11A DNAH5 DNAH11

9.24e-04152396HP:0001217
HumanPhenoSupernumerary spleens

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

9.35e-04101395HP:0009799
HumanPhenoAbnormal bronchus morphology

NEK10 ODAD1 DNAAF5 MIF ATP11A DNAH5 DNAH11

1.05e-03215397HP:0025426
HumanPhenoDecreased fertility in females

NEK10 ODAD1 DNAAF5 DNAH5 DNAH11

1.07e-03104395HP:0000868
HumanPhenoAbnormal respiratory epithelium morphology

ODAD1 DNAAF5 DNAH11

1.19e-0328393HP:0012253
HumanPhenoAbnormal respiratory motile cilium morphology

ODAD1 DNAAF5 DNAH11

1.19e-0328393HP:0005938
HumanPhenoAbnormal pulmonary interstitial morphology

NEK10 ODAD1 DNAAF5 ATP11A DNAH5 DNAH11

1.25e-03161396HP:0006530
MousePhenobiventricular, ambiguous atrioventricular connection

DNAH5 DNAH11

4.19e-052912MP:0011511
MousePhenodual inferior vena cava

FUZ BRD2 DNAH5 DNAH11

6.71e-0534914MP:0011683
MousePhenoenlarged brain ventricles

RB1 DNAAF5 BRD2 ASPM WDFY3 YWHAQ DNAH5

6.96e-05156917MP:0011380
MousePhenoabnormal brain ventricle size

RB1 DNAAF5 BRD2 ASPM WDFY3 YWHAQ DNAH5

9.53e-05164917MP:0013229
MousePhenobiventricular, discordant atrioventricular connection

DNAH5 DNAH11

1.25e-043912MP:0011510
MousePhenoabsent pectinate muscle

BRD2 ATP11A

1.25e-043912MP:0013809
MousePhenoimmotile respiratory cilia

DNAAF5 DNAH5 DNAH11

1.70e-0417913MP:0011649
DomainHECW_N

HECW1 HECW2

3.13e-0521052IPR032348
DomainHECW_N

HECW1 HECW2

3.13e-0521052PF16562
Domain-

NEK10 RICTOR PSMD5 DNAAF5 IFRD2 ASPM WDFY3 SYMPK

3.64e-0522210581.25.10.10
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH5 DNAH11

6.01e-05141053IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH5 DNAH11

6.01e-05141053IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH5 DNAH11

6.01e-05141053IPR013602
DomainDHC_N2

DNAH3 DNAH5 DNAH11

6.01e-05141053PF08393
DomainMT

DNAH3 DNAH5 DNAH11

6.01e-05141053PF12777
DomainAAA_8

DNAH3 DNAH5 DNAH11

6.01e-05141053PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH5 DNAH11

6.01e-05141053IPR011704
DomainAAA_5

DNAH3 DNAH5 DNAH11

6.01e-05141053PF07728
DomainDHC_fam

DNAH3 DNAH5 DNAH11

7.48e-05151053IPR026983
DomainDynein_heavy_dom

DNAH3 DNAH5 DNAH11

7.48e-05151053IPR004273
DomainDynein_heavy

DNAH3 DNAH5 DNAH11

7.48e-05151053PF03028
DomainC2

HECW1 UNC13D ESYT2 HECW2 PLCG1 CADPS2

9.68e-051311056PF00168
DomainC2

HECW1 UNC13D ESYT2 HECW2 PLCG1 CADPS2

1.24e-041371056SM00239
DomainARM-type_fold

NEK10 RICTOR PSMD5 FOCAD DNAAF5 IFRD2 ASPM WDFY3 SYMPK

1.25e-043391059IPR016024
DomainARM-like

NEK10 RICTOR PSMD5 DNAAF5 IFRD2 ASPM WDFY3 SYMPK

1.43e-042701058IPR011989
DomainC2

HECW1 UNC13D ESYT2 HECW2 PLCG1 CADPS2

1.51e-041421056PS50004
DomainC2_dom

HECW1 UNC13D ESYT2 HECW2 PLCG1 CADPS2

3.29e-041641056IPR000008
DomainDUF1041

UNC13D CADPS2

6.45e-0471052PF06292
DomainMunc13_1

UNC13D CADPS2

6.45e-0471052IPR014770
DomainCAPS_dom

UNC13D CADPS2

6.45e-0471052IPR010439
DomainMHD1

UNC13D CADPS2

6.45e-0471052PS51258
DomainDHC_N1

DNAH5 DNAH11

8.57e-0481052PF08385
DomainDynein_heavy_dom-1

DNAH5 DNAH11

8.57e-0481052IPR013594
DomainP-loop_NTPase

DNAH3 NDST2 DHX33 PFKFB3 SBNO2 ERAL1 ASPM ABCD2 DNAH5 CARD14 MOV10 CHST3 DNAH11

9.34e-0484810513IPR027417
Domain-

DNAH3 NDST2 DHX33 PFKFB3 SBNO2 ERAL1 ABCD2 DNAH5 CARD14 MOV10 CHST3 DNAH11

9.82e-04746105123.40.50.300
DomainGDS_CDC24_CS

OBSCN PREX2 TIAM1

1.36e-03391053IPR001331
Domain-

HECW1 UNC13D ESYT2 HECW2 PLCG1

1.49e-0314810552.60.40.150
DomainPH

OBSCN PREX2 TIAM1 PRKD1 PLCG1 CADPS2

1.87e-032291056PF00169
DomainPH_dom-like

OBSCN PREX2 PTK2 TIAM1 PRKD1 PLCG1 WDFY3 CADPS2

2.79e-034261058IPR011993
DomainPH

OBSCN PREX2 TIAM1 PRKD1 PLCG1 CADPS2

4.85e-032781056SM00233
DomainPH_DOMAIN

OBSCN PREX2 TIAM1 PRKD1 PLCG1 CADPS2

4.94e-032791056PS50003
DomainPH_domain

OBSCN PREX2 TIAM1 PRKD1 PLCG1 CADPS2

5.02e-032801056IPR001849
DomainDH_1

OBSCN PREX2 TIAM1

5.37e-03631053PS00741
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

OBSCN BEND3 FHIP2A AGO4 CADPS2 DNAH5 MOV10

3.51e-08101110710997877
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP28 ASH1L USP25 FUZ LMO3 PSMD5 PTK2 ADD3 RUFY2 FOCAD BRD2 TIAM1 IFT122 PLCG1 WDFY3 GFPT2 CADPS2 AFF4

1.17e-0712851101835914814
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PANK3 PRAMEF22 ASH1L OBSCN UNC13D RICTOR SBNO2 ERAL1 DZIP3 ATP11A TIMELESS PLCG1 GFPT2 YWHAQ ATP2B1 AFF4

3.19e-0710841101611544199
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH3 DNAH5 DNAH11

1.07e-06711039256245
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

NEBL PRAMEF22 CCDC18 DHX33 TWF1 RUFY2 BRD2 HECW2 TTLL11 ASPM ATP11A TIMELESS TRAF3IP3 YWHAQ PLXNA2 SYMPK

1.89e-0612421101630973865
Pubmed

Primary Ciliary Dyskinesia

ODAD1 DNAAF5 DNAH5 DNAH11

3.18e-0632110420301301
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SIN3B EMC1 NEBL RHBDD2 RICTOR ICE1 DHX33 HEXIM1 TWF1 ESYT2 BRD2 IFRD2 DNAJC1 YWHAQ AFF4 MOV10 SMG6

4.75e-0614971101731527615
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RB1 RICTOR PSMD5 FASTKD2 DHX33 BIRC6 PTK2 FBXL18 ERAL1 MIF ASPM PLCG1 WDFY3 YWHAQ ATP2B1 MOV10

5.62e-0613531101629467282
Pubmed

In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development.

SEMA7A NHLH1 PLXNA2

6.63e-0612110321300888
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RALGDS EMC1 RTN4 RHBDD2 RICTOR FHIP2A PTK2 HEXIM1 SBNO2 TIMELESS IFT122

7.15e-066501101138777146
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RALGDS EMC1 USP28 RTN4 ICE1 FASTKD2 AGO4 HECW2 YWHAQ SMG6

7.34e-065291101014621295
Pubmed

UCP2 upregulation promotes PLCγ-1 signaling during skin cell transformation.

UCP2 PLCG1

9.91e-062110228574619
Pubmed

Focal adhesion kinase promotes phospholipase C-gamma1 activity.

PTK2 PLCG1

9.91e-062110210430888
Pubmed

Focal adhesion kinase-related fakB is regulated by the integrin LFA-1 and interacts with the SH3 domain of phospholipase C gamma 1.

PTK2 PLCG1

9.91e-06211028660853
Pubmed

Protein kinase C mu is negatively regulated by 14-3-3 signal transduction proteins.

PRKD1 YWHAQ

9.91e-062110210092600
Pubmed

Capped small RNAs and MOV10 in human hepatitis delta virus replication.

AGO4 MOV10

9.91e-062110218552826
Pubmed

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

DNAH5 DNAH11

9.91e-062110232357925
Pubmed

Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.

NEBL PTK2

9.91e-062110228667800
Pubmed

Characterization of alternatively spliced products and tissue-specific isoforms of USP28 and USP25.

USP28 USP25

9.91e-062110211597335
Pubmed

Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location.

OR4F4 OR4F17

9.91e-062110211689484
Pubmed

Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes.

OR4F4 OR4F17

9.91e-062110211689483
Pubmed

Phosphohistidine signaling promotes FAK-RB1 interaction and growth factor-independent proliferation of esophageal squamous cell carcinoma.

RB1 PTK2

9.91e-062110236513743
Pubmed

USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines.

USP28 USP25

9.91e-062110232578360
Pubmed

Ciliary defects and genetics of primary ciliary dyskinesia.

DNAH5 DNAH11

9.91e-062110219410201
Pubmed

Interleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNA.

IRAK2 PRKD1

9.91e-062110222928050
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPPK1 SEMA7A OBSCN ICE1 BIRC6 SBNO2 FOCAD BRD2 TRAPPC12 IFRD2 PLCG1 WDFY3 SMG6 SYMPK

1.06e-0511051101435748872
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH5 DNAH11

1.09e-051411039373155
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SIN3B HECW1 USP28 LMO3 PTK2 SPICE1 TWF1 DZIP3 PRKD1 WDFY3 YWHAQ AFF4 SMG6

1.16e-059631101328671696
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

KNTC1 EPO EPPK1 EMC1 RTN4 PFKFB3 PTK2 DNAAF5 TIAM1 MIF ASPM BCL10 YWHAQ MTX1 MOV10

1.31e-0512841101517353931
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EMC1 RTN4 CCDC18 RICTOR FASTKD2 ADD3 SPICE1 ESYT2 BRD2 TIAM1 ERAL1 SSX2IP ASPM IFT122 DNAJC1 ATP2B1

1.81e-0514871101633957083
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ICE1 FASTKD2 SBNO2 SSX2IP WDFY3

1.88e-05102110510231032
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SIN3B DNAH3 RB1 OBSCN UNC93A ICE1 BIRC6 FOCAD HECW2 KCNG4 SYMPK

2.26e-057361101129676528
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KNTC1 SIN3B HECW1 RICTOR BIRC6 RUFY2 SSX2IP ATP11A MOV10

2.81e-05493110915368895
Pubmed

Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.

USP28 USP25

2.97e-053110230926242
Pubmed

Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities.

USP28 USP25

2.97e-053110230926243
Pubmed

CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation.

ODAD1 DNAH5

2.97e-053110225192045
Pubmed

The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes.

BCL10 CARD14

2.97e-053110227113748
Pubmed

Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia.

ODAD1 DNAH5

2.97e-053110223261302
Pubmed

CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B.

BCL10 CARD14

2.97e-053110211278692
Pubmed

Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily.

USP28 USP25

2.97e-053110229131570
Pubmed

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.

BCL10 CARD14

2.97e-053110227071417
Pubmed

FGFR1 Is Critical for RBL2 Loss-Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer.

RB1 PLCG1

2.97e-053110232973083
Pubmed

Erythropoietin treatment of human ovarian cancer cells results in enhanced signaling and a paclitaxel-resistant phenotype.

EPO BCL10

2.97e-053110217893875
Pubmed

Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase.

RB1 PTK2

2.97e-053110215640164
Pubmed

FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression.

RB1 PTK2

2.97e-053110236857183
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

NEBL NDST2 PFKFB3 ADD3 RUFY2 CYP26C1 DNAJC1 CHST3

5.45e-05415110816385451
Pubmed

HMGB1-mediated elevation of KLF7 facilitates hepatocellular carcinoma progression and metastasis through upregulating TLR4 and PTK2.

PTK2 KLF7

5.92e-054110237554278
Pubmed

Retinoblastoma susceptibility gene product pRB activates hypoxia-inducible factor-1 (HIF-1).

EPO RB1

5.92e-054110215674338
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAH5 DNAH11

5.92e-054110218492703
Pubmed

Targeting of PFKFB3 with miR-206 but not mir-26b inhibits ovarian cancer cell proliferation and migration involving FAK downregulation.

PFKFB3 PTK2

5.92e-054110235107852
Pubmed

Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation.

BCL10 CARD14

5.92e-054110211356195
Pubmed

Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes.

OR4F4 OR4F17

5.92e-05411029384599
Pubmed

Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction.

BCL10 CARD14

5.92e-054110211387339
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ASH1L OBSCN PTK2 SBNO2 DNAAF5 ESYT2 KLF7 TTLL11 ATP11A PRKD1 IFT122 PLCG1 ATP2B1 AFF4 SMG6

7.14e-0514891101528611215
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

EMC1 PANK3 CCDC18 RICTOR SPICE1 TWF1 ESYT2 TIAM1 SSX2IP YWHAQ ATP2B1

9.25e-058611101136931259
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

ASH1L C15orf40 IFT122 WDFY3 MTX1 CCDC136 AFF4 SYMPK

9.56e-05450110816751776
Pubmed

The potential role of transient receptor potential type A1 as a mechanoreceptor in human periodontal ligament cells.

ASIC3 TRPV4

9.85e-055110224206072
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

DNAH5 DNAH11

9.85e-055110222499950
Pubmed

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase.

PTK2 PLCG1

9.85e-05511027997267
Pubmed

Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association.

PRKD1 YWHAQ

9.85e-055110219011111
Pubmed

Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B.

BCL10 CARD14

9.85e-055110211259443
Pubmed

Synergistic activation of PKD by the B cell antigen receptor and CD19 requires PI3K, Vav1 and PLCgamma.

PRKD1 PLCG1

9.85e-055110216380231
Pubmed

NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.

HECW1 HECW2

9.85e-055110214684739
Pubmed

Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5.

PRKD1 YWHAQ

9.85e-055110215367659
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH5 DNAH11

9.85e-055110226909801
Pubmed

GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cells.

PLCG1 YWHAQ

9.85e-055110218292392
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

HECW1 PTK2 KCNA5 BRD2 HECW2 GFPT2 YWHAQ DNAH5 ATP2B1 DNAH11

1.11e-047301101034857952
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

EMC1 CCDC18 RICTOR BIRC6 SPICE1 ESYT2 BRD2 TIAM1 SSX2IP YWHAQ ATP2B1 SYMPK

1.24e-0410491101227880917
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

EMC1 USP28 RTN4 USP25 BRD2 SSX2IP DNAJC1 MTX1 ATP2B1 MOV10

1.44e-047541101033060197
Pubmed

Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex.

SIN3B RB1

1.47e-046110211909966
Pubmed

InVision: An optimized tissue clearing approach for three-dimensional imaging and analysis of intact rodent eyes.

RB1 CCDC136

1.47e-046110234430805
Pubmed

USP37 Deubiquitinates CDC73 in HPT-JT Syndrome.

USP28 USP25

1.47e-046110235742816
Pubmed

Uncoupling proteins 2 and 3 interact with members of the 14.3.3 family.

UCP2 YWHAQ

1.47e-046110210785390
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH5 DNAH11

1.47e-046110233347437
Pubmed

Protein kinase C [micro] is regulated by the multifunctional chaperon protein p32.

PRKD1 YWHAQ

1.47e-046110210831594
Pubmed

Histone deacetylase 1 can repress transcription by binding to Sp1.

SIN3B RB1

1.47e-046110210409740
Pubmed

Functional reprogramming of regulatory T cells in the absence of Foxp3.

RICTOR PFKFB3

1.47e-046110231384057
Pubmed

Mast cell differentiation and activation is closely linked to expression of genes coding for the serglycin proteoglycan core protein and a distinct set of chondroitin sulfate and heparin sulfotransferases.

NDST2 CHST3

1.47e-046110219915053
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SIN3B NEBL USP28 RTN4 ICE1 ADD3 TWF1 MIF PLCG1 YWHAQ AFF4

1.88e-049341101133916271
Pubmed

HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.

HECW1 HECW2 DZIP3 PLCG1

1.96e-0490110435671810
Pubmed

P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.

RICTOR PREX2

2.06e-047110217565979
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH5 DNAH11

2.06e-047110231178125
Pubmed

Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip.

SEMA7A LMO3 NHLH1 PLXNA2

2.42e-0495110421440680
Pubmed

Direct phosphorylation of proliferative and survival pathway proteins by RET.

PTK2 PLCG1

2.74e-048110216153436
Pubmed

The ubiquitin ligase Siah1 controls ELL2 stability and formation of super elongation complexes to modulate gene transcription.

HEXIM1 AFF4

2.74e-048110222483617
Pubmed

Protein kinase C mu (PKC mu) associates with the B cell antigen receptor complex and regulates lymphocyte signaling.

PRKD1 PLCG1

2.74e-04811028885868
Pubmed

Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons.

RB1 ATP2B1

2.74e-048110222456337
Pubmed

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

UNC13D CADPS2

2.74e-048110225609709
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

RB1 IRAK2 IFRD2 DZIP3 YWHAQ MOV10

2.91e-04283110621903422
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

SIN3B C15orf40 UNC13D RICTOR BIRC6 PREX2 HEXIM1 FBXL18 BRD2 MIF ASPM PLCG1 MTX1

2.94e-0413271101332694731
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ASH1L PSMD5 TWF1 ESYT2 TRAPPC12 SSX2IP GFPT2 DNAH11 SYMPK

3.50e-04689110936543142
Pubmed

Characterization of a 190-kilobase pair domain of human type I hair keratin genes.

KRT38 KRT37

3.52e-04911029756910
Pubmed

RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.

SIN3B RB1

3.52e-049110211283269
Pubmed

Human hair keratins.

KRT38 KRT37

3.52e-04911027686952
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

EPPK1 EMC1 PSMD5 DHX33 BIRC6 TIMELESS PLCG1 DNAH5 MOV10

4.09e-04704110929955894
Pubmed

The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.

KRT38 KRT37

4.39e-0410110210391933
Pubmed

Macrophage migration inhibitory factor MIF interferes with the Rb-E2F pathway.

RB1 MIF

4.39e-0410110215664192
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

RICTOR ADD3 RUFY2 KLHL38 ESYT2 ATP11A ATP2B1 PLXNA2

4.65e-04569110830639242
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

EMC1 RICTOR BIRC6 ADD3 CNPY3 ATP11A GFPT2 ATP2B1 CHST3

4.76e-04719110935337019
Pubmed

Binding of pRB to the PHD protein RBP2 promotes cellular differentiation.

RB1 BRD2

5.35e-0411110215949438
InteractionGYPA interactions

KNTC1 RB1 FASTKD2 RUFY2 FOCAD DNAAF5 TIMELESS DNAJC1 SYMPK

3.47e-071741069int:GYPA
InteractionNDC80 interactions

RB1 CCDC18 ICE1 BIRC6 HEXIM1 SPICE1 FOCAD SSX2IP ASPM DZIP3 CCDC136

7.73e-0731210611int:NDC80
InteractionTXLNG interactions

ODAD1 SPICE1 SSX2IP KRT38 KRT37 MOV10

1.31e-05981066int:TXLNG
InteractionKRT4 interactions

EPPK1 USP25 HEXIM1 KRT38 KRT37

1.87e-05621065int:KRT4
InteractionKRT8 interactions

EPPK1 CCDC18 RICTOR BIRC6 HEXIM1 SPICE1 ESYT2 SSX2IP YWHAQ KRT38 KRT37

2.09e-0544110611int:KRT8
InteractionACTR5 interactions

KNTC1 HEXIM1 SPICE1 BRD2 HECW2

3.87e-05721065int:ACTR5
InteractionRABGAP1L interactions

RB1 HEXIM1 DZIP3 WDFY3 KRT37 SYMPK

4.74e-051231066int:RABGAP1L
InteractionTMEM171 interactions

KNTC1 HECW1 HECW2 MTX1 SYMPK

5.03e-05761065int:TMEM171
InteractionPRRG4 interactions

HECW1 NEBL PTK2 BCL10

5.16e-05391064int:PRRG4
GeneFamilyDyneins, axonemal

DNAH3 DNAH5 DNAH11

4.12e-0517733536
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

HECW1 HECW2 CADPS2

4.10e-0436733823
CoexpressionGSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_UP

HECW1 TMC7 SEMA7A USP28 SBNO2 UCP2 GFPT2 MOV10

1.89e-061991098M8263
CoexpressionGSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_DN

RICTOR PSMD5 ICE1 FHIP2A BIRC6 IFRD2 MOV10

1.78e-051951097M9813
CoexpressionGSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP

RALGDS DNAH3 NDST2 USP25 UNC93A TRAF3IP3 WDFY3

1.96e-051981097M3200
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

NEBL LMO3 PTK2 ATP11A PRKD1 WDFY3 CADPS2

6.24e-0719811071996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

3.98e-06169110614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PFKFB3 PREX2 KCNA5 TIMELESS PLXNA2

5.20e-061771106ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PFKFB3 PREX2 KCNA5 TIMELESS PLXNA2

5.20e-061771106f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PFKFB3 PREX2 KCNA5 TIMELESS PLXNA2

5.20e-061771106cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NEK10 UNC93A LMO3 PFKFB3 UCP2 MIF

5.72e-061801106b927e7380369da6f92ba23d96103519884b70595
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 EPPK1 NEK10 ODAD1 DNAH5 DNAH11

5.72e-0618011061f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

6.70e-061851106f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

6.90e-06186110676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL PFKFB3 PTK2 PRKD1 WDFY3 CADPS2

7.57e-061891106830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A ADD3 KLF7 TRPV4 PLXNA2 DNAH11

8.03e-061911106df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCellASK428-Epithelial-Ciliated|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

8.03e-0619111060c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 NEK10 ODAD1 DNAH5 PLXNA2 DNAH11

8.53e-061931106ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

8.78e-0619411064a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 NEBL NEK10 CADPS2 DNAH5 DNAH11

9.04e-061951106fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.04e-061951106649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.04e-0619511060e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 ODAD1 FUZ DZIP3 DNAH5 DNAH11

9.04e-0619511060fbba312e9ba9b70b4b814b67b6eb1f6544aaf6d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.04e-061951106581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.04e-06195110693b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.04e-06195110679dc031258579ea328181dda33710dd897f1064a
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 NEBL NEK10 CADPS2 DNAH5 DNAH11

9.04e-061951106eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.04e-061951106129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.04e-0619511063e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.04e-0619511063486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 NEBL LMO3 SSX2IP CADPS2 CCDC136

9.04e-061951106787e95fb59c40bba784544b662fac37606ae1427
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.31e-061961106de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.31e-06196110627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 NEBL PTK2 ASPM DNAH5 DNAH11

9.31e-061961106af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 NEBL PTK2 ASPM DNAH5 DNAH11

9.31e-0619611066d02d494196e3f857d53eea46d9419690d43beca
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.58e-0619711066865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.58e-06197110691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.58e-06197110622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.58e-0619711063bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.58e-061971106e453d085182364ca347cbcc9dc995c62c3353016
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.58e-06197110687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

DNAH3 NEK10 ODAD1 LMO3 DNAH5 DNAH11

9.58e-06197110618fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.58e-061971106d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ASH1L RICTOR HEXIM1 ADD3 MIF TRAF3IP3

9.86e-0619811064c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

9.86e-061981106ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEBL NEK10 ODAD1 DNAH5 DNAH11

9.86e-061981106d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

USP25 BIRC6 PTK2 FOCAD WDFY3 CADPS2

1.01e-05199110694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

1.04e-0520011066a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

1.04e-052001106bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

1.04e-052001106f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

1.04e-052001106d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH3 NEK10 ODAD1 DZIP3 DNAH5 DNAH11

1.04e-052001106cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEK10 UNC13D DHX33 TIMELESS DNAJC1

3.67e-0515111057270b8bbfae659e110bd9d513b602120b25de3dd
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

SEMA7A UNC13D BIRC6 PREX2 HECW2

4.98e-0516111051973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC42 DNAH5 MOV10 CHST3 DNAH11

5.60e-0516511051703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NEK10 ODAD1 IFT122 CADPS2 DNAH11

6.10e-0516811059a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW2 TRPV4 PRKD1 PLXNA2 CARD14

6.45e-0517011058e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW2 TRPV4 PRKD1 PLXNA2 CARD14

6.45e-05170110567d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellcritical-Epithelial-unknown_epithelial|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PFKFB3 HEXIM1 BRD2 NHLH1 GFPT2

7.01e-0517311054144b1cdefa8c37b6ac7a6d249fa5292ffb2b8b2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA7A NDST2 CCDC18 UNC13D DNAH11

7.81e-05177110586c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

8.02e-051781105de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPPK1 NEK10 ODAD1 DNAH5 DNAH11

8.45e-05180110592fb01b91261b3103454924cde56add337b41844
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

8.67e-051811105dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH3 NEK10 ODAD1 TRPV4 DNAH11

8.90e-0518211057ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

8.90e-051821105fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NEBL LMO3 ATP11A PRKD1 CADPS2

9.13e-0518311056847c1252d6bb105524f812658112517fd351eab
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 ODAD1 KLHL38 DNAH5 DNAH11

9.37e-051841105264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 ODAD1 KLHL38 DNAH5 DNAH11

9.37e-051841105d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 ODAD1 KLHL38 DNAH5 DNAH11

9.37e-05184110522010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 ATP11A PRKD1 CADPS2 PLXNA2

9.61e-0518511050d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

KNTC1 SEMA7A DHX33 BIRC6 RUFY2

9.61e-051851105a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

9.61e-0518511055e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

9.61e-0518511050998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

9.61e-0518511053e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

9.61e-05185110518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

KNTC1 SEMA7A ASH1L BIRC6 RUFY2

9.86e-0518611058571956890fc9894d766ba294a28e376b4aba428
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

1.01e-0418711059e10ed56090d82589bc457788282f664b70ace4b
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

DNAH3 NEK10 DZIP3 DNAH5 DNAH11

1.04e-0418811056833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCelldroplet-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PREX2 KLF7 HECW2 TIMELESS

1.04e-041881105ca3be1942b179b512ab242acded31f1e3748c753
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA7A PFKFB3 PREX2 KCNA5 PLXNA2

1.04e-04188110520072a2a3f9ecbe727c850629f19420cf60e4bc5
ToppCellfacs-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA7A PFKFB3 PREX2 KCNA5 PLXNA2

1.04e-041881105dd817059e1b4225e84733559f7839cc973b7dfd6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA7A IRAK2 PREX2 KLF7 PLXNA2

1.04e-041881105c2c51c6526defe2600302901159b8abbb58d7595
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA7A PFKFB3 PREX2 KCNA5 PLXNA2

1.04e-0418811056ab5ce8569f896a0fe7a76b8b4a83661e5499b8c
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA7A FUZ KCNA5 UCP2 CNPY3

1.04e-0418811051f820cb19eb0e15f0eb69d07e457072bbdad8ecb
ToppCell3'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HECW1 PTK2 BCL10 CARD14 SYMPK

1.06e-0418911057dad62bd50c197838058e89abd0ee387de3e83cd
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

1.06e-041891105a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PREX2 KLF7 HECW2 DNAJC1 CADPS2

1.06e-041891105b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellfacs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PREX2 KCNA5 KLF7 PLXNA2

1.06e-0418911051be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PFKFB3 PREX2 KCNA5 PLXNA2

1.06e-041891105f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LMO3 PFKFB3 ESYT2 TRPV4 CADPS2

1.06e-041891105fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PREX2 KCNA5 KLF7 PLXNA2

1.06e-04189110530dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 NEK10 ODAD1 DZIP3 DNAH5

1.06e-041891105b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PFKFB3 PREX2 KCNA5 PLXNA2

1.06e-041891105e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PFKFB3 PREX2 KCNA5 PLXNA2

1.06e-0418911055559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

1.06e-04189110527329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

1.06e-0418911053e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 LMO3 FOCAD SSX2IP CADPS2

1.06e-041891105c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA7A FUZ KCNA5 UCP2 CNPY3

1.09e-041901105c44aae2e0d3cc84a187e12917fd8c2d7483f41d8
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

PREX2 PTK2 HECW2 CADPS2 PLXNA2

1.09e-041901105812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 NEK10 ODAD1 DNAH5 DNAH11

1.09e-0419011057031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A PFKFB3 PREX2 KCNA5 PLXNA2

1.09e-04190110538a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

NEK10 PFKFB3 PTK2 ESYT2 PLXNA2

1.09e-041901105f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RTN4 PREX2 ADD3 ATP2B1 AFF4

1.09e-041901105d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

OBSCN PREX2 KLF7 HECW2 DNAJC1

1.09e-0419011050a351609a72fd638c84b2435782e312ee6a33aac
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DNAH3 NEK10 ODAD1 DZIP3 DNAH11

1.09e-041901105426a4806f6e39d4d57c6746609d30bb3ca62df7d
DrugGSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A

DNAH3 EPPK1 PTK2 SBNO2 TIAM1 UCP2 SSX2IP WDFY3

4.73e-0619610986585_DN
DrugFluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; PC3; HT_HG-U133A

EPPK1 EMC1 NEBL ASIC3 UCP2 IFT122 CADPS2 CHST3

4.73e-0619610985741_DN
DrugClofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

ASH1L HEXIM1 KLF7 SSX2IP ATP11A TIMELESS PLCG1 SYMPK

4.91e-0619710983239_DN
DiseasePrimary Ciliary Dyskinesia

ODAD1 DNAAF5 IFT122 DNAH5 DNAH11

6.42e-07471035C4551720
DiseasePrimary ciliary dyskinesia

ODAD1 DNAAF5 DNAH5 DNAH11

7.57e-06361034cv:C0008780
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

7.21e-0541032DOID:0050144 (is_implicated_in)
Diseasepulmonary hypertension (is_implicated_in)

EPO PTK2 KCNA5

1.57e-04301033DOID:6432 (is_implicated_in)
Diseasesmoking behavior

PTK2 KLF7 DNAJC1 CADPS2 PLXNA2 CHST3 SMG6

1.99e-043411037EFO_0004318
Diseasemean arterial pressure, alcohol drinking

NEK10 ICE1 ATP2B1 MOV10

3.93e-04981034EFO_0004329, EFO_0006340
DiseaseColorectal Carcinoma

RALGDS DNAH3 RTN4 OBSCN PREX2 TIAM1 PRKD1 TRAF3IP3 ABCD2

7.98e-047021039C0009402
DiseaseMetastatic melanoma

NEK10 PTK2 PRKD1

9.00e-04541033C0278883
Diseasereticulocyte count

ASH1L BEND3 BIRC6 SBNO2 FBXL18 ERAL1 IFRD2 DZIP3 ATP11A ATP2B1 SMG6

1.07e-03104510311EFO_0007986
DiseaseKartagener syndrome (implicated_via_orthology)

DNAH5 DNAH11

1.07e-03141032DOID:0050144 (implicated_via_orthology)
Diseasediabetic neuropathy (is_implicated_in)

EPO UCP2

1.07e-03141032DOID:9743 (is_implicated_in)
Diseasehypertension (implicated_via_orthology)

PTK2 ADD3 UCP2 MIF

1.07e-031281034DOID:10763 (implicated_via_orthology)
DiseaseBrain Ischemia

RB1 ADD3 UCP2

1.22e-03601033C0007786
DiseaseCerebral Ischemia

RB1 ADD3 UCP2

1.22e-03601033C0917798
Diseaselung small cell carcinoma (is_marker_for)

RICTOR PTK2

1.40e-03161032DOID:5409 (is_marker_for)
DiseaseSpondyloepiphyseal Dysplasia

TRPV4 CHST3

1.40e-03161032C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

TRPV4 CHST3

1.40e-03161032C3541456
DiseaseSchwartz-Jampel Syndrome, Type 1

TRPV4 CHST3

1.40e-03161032C4551479
DiseaseSchwartz-Jampel Syndrome

TRPV4 CHST3

1.40e-03161032C0036391
DiseaseMelnick-Needles Syndrome

TRPV4 CHST3

1.40e-03161032C0025237
DiseaseVan Buchem disease

TRPV4 CHST3

1.59e-03171032C0432272
Diseaselymphocyte count

EPO EPPK1 RB1 RTN4 BEND3 PFKFB3 PREX2 SBNO2 FOCAD FBXL18 BRD2 DZIP3 SMG6

1.76e-03146410313EFO_0004587
DiseaseOsteochondrodysplasias

TRPV4 CHST3

1.99e-03191032C0029422
DiseaseDyschondroplasias

TRPV4 CHST3

1.99e-03191032C0013366
Diseaseautism spectrum disorder (implicated_via_orthology)

NDST2 ASH1L WDFY3 CADPS2

2.02e-031521034DOID:0060041 (implicated_via_orthology)
DiseaseMammary Neoplasms, Experimental

RB1 PTK2 UCP2 MIF

2.16e-031551034C0024668
DiseaseMultiple Epiphyseal Dysplasia

TRPV4 CHST3

2.20e-03201032C0026760
Diseaseosteoarthritis, knee

EPPK1 SEMA7A BRD2 SMG6

2.32e-031581034EFO_0004616
Diseaseintellectual disability (implicated_via_orthology)

RB1 NDST2 YWHAQ

2.32e-03751033DOID:1059 (implicated_via_orthology)
Diseasesmoking status measurement

LMO3 BIRC6 PTK2 ADD3 FOCAD KLF7 HECW2 DNAJC1 CADPS2 PLXNA2 SMG6

2.43e-03116010311EFO_0006527
DiseaseDisproportionate short stature

TRPV4 IFT122 CHST3

2.51e-03771033C0878659
DiseaseLung diseases

DNAH5 AFF4 DNAH11

2.60e-03781033C0024115
DiseaseBronchiectasis

DNAH5 DNAH11

2.66e-03221032C0006267
DiseaseNeoplasm of the genitourinary tract

RB1 BCL10

3.17e-03241032cv:C0042065

Protein segments in the cluster

PeptideGeneStartEntry
RAELLQLYERCILLD

SMG6

616

Q86US8
KALRLCRALALLEDE

ESYT2

156

A0FGR8
RSICTTVLELLDKYL

YWHAQ

91

P27348
VYFICLLRDDLLLRQ

ASH1L

2651

Q9NR48
LYRALLELLRAIASC

BIRC6

4391

Q9NR09
YLECKLALAFRTRLV

ABCD2

166

Q9UBJ2
LTRCKLASLYRLVDL

ADD3

136

Q9UEY8
TTSLLRDCYLLEEKE

SSX2IP

416

Q9Y2D8
EEVLSCRYLRLSKEN

C16orf78

211

Q8WTQ4
RLSLCEKALAEYLET

DNAH11

1606

Q96DT5
LIAIRKACISLEEDY

AGO4

686

Q9HCK5
SKEDCIARYKLLVEL

DNAJC1

531

Q96KC8
TYLSFLCARLLDLRK

ASPM

1251

Q8IZT6
ECALLGLLLDLKRDY

ATP2B1

546

P20020
KRLTVLCLRCESLLY

AFF4

996

Q9UHB7
LCLRCESLLYLRLFK

AFF4

1001

Q9UHB7
LFSKLERTCELIYLT

RB1

161

P06400
ADCLLSKEQLRSIYE

BEND3

551

Q5T5X7
PFYKALLRILCDLSD

HECW2

1331

Q9P2P5
LLRILCDLSDLEYLD

HECW2

1336

Q9P2P5
LDLRELECKIGERYI

PRKD1

846

Q15139
DKAEREPLLLCATYL

IFT122

801

Q9HBG6
DLLCRLELYRAAQII

IRAK2

76

O43187
FYKALLRLPCDLSDL

HECW1

1366

Q76N89
IATYRNLLESEDCKL

KRT37

401

O76014
LILLDRLCYLKEQED

METTL25

561

Q8N6Q8
IATYRNLLESEDCKL

KRT38

401

O76015
SKLRLCRSYEEIVQL

KCNG4

86

Q8TDN1
ELIKEYLELEKCLSR

HEXIM1

286

O94992
SLYQGVCKLLRLDDL

PLXNA2

131

O75051
ITIRDYSDLKRLRCL

NEK10

21

Q6ZWH5
RVIKLACTDTYRLDI

OR4F5

176

Q8NH21
VLRCLLAYFLDKSAE

PFKFB3

391

Q16875
DIFLCDVDIRLSVKL

ERAL1

421

O75616
TKANLILCRRDYLRL

LMO3

56

Q8TAP4
LLLYIEDLLNRCSSK

KNTC1

756

P50748
DILLSRDKLLSETCL

KLF7

96

O75840
LEEIKSFRELTCLDL

LRRC42

166

Q9Y546
YSKLLCGLLAERLRI

MIF

76

P14174
LTILEILDYLCEVFR

ASIC3

451

Q9UHC3
RVIKLACTDTYRLDI

OR4F17

176

Q8NGA8
ERLVLCYEDALNKLS

ODAD1

261

Q96M63
YEDIIICLRLALLNE

RICTOR

81

Q6R327
DILRLCKYRDILLSE

DZIP3

501

Q86Y13
SCVLLKSLDLTYDRR

MAGEA13P

171

A6NCF6
LDELDCLVKGLLYID

PANK3

136

Q9H999
LELCSSEELLDRLYR

OBSCN

6541

Q5VST9
LSKIEILRLAICYIS

NHLH1

111

Q02575
DLERARLFCYSLLKE

ICE1

2006

Q9Y2F5
KSNVDLRRSLYALCL

KCNA5

591

P22460
ASRCRSLQEELYLLK

CARD14

216

Q9BXL6
LLALRYCKDRGALTV

GFPT2

431

O94808
LIKRCSEFELRLEGY

DNAH3

786

Q8TD57
RLQERCGLYKSELEI

CCDC18

286

Q5T9S5
SLLLILCFRESYDRL

SLC49A4

456

Q96SL1
LENLRVYLCEKIIAE

BCL10

21

O95999
LIEVTETICKRLLDY

CNPY3

96

Q9BT09
ALLCYERALRLAADL

IFIT1B

456

Q5T764
LREAISDSLLRKYSC

DHX33

176

Q9H6R0
RLICDSRVLERYLLE

EPO

31

P01588
CLEKAALINYTRLTE

CADPS2

806

Q86UW7
LRYVDCVVKEVLRLL

CYP26C1

366

Q6V0L0
VLDLLFKRYGRCDAL

RALGDS

156

Q12967
LLERRLTLADALEKC

IFRD2

176

Q12894
LCGYRLRKDLTTELS

EMC1

681

Q8N766
DLYLERLLLCVQALV

DNAAF5

491

Q86Y56
CELLTDRLASLYKAL

FHIP2A

306

Q5W0V3
RRKDLELYISIAKCL

FOCAD

1546

Q5VW36
VERLKKDLRASYCLI

FUZ

121

Q9BT04
AYDKSLDCFRRLLLI

DNAH5

3986

Q8TE73
RVIKLACTDTYRLDI

OR4F4

176

Q96R69
EKELYREARECLTLL

MTX1

316

Q13505
CTIKELRRLFLVDDL

RTN4

1101

Q9NQC3
YLRCLIIQRDLLSEF

RUFY2

121

Q8WXA3
RYCITKLDRELRGLD

MOV10

841

Q9HCE1
CTSLEKLLLYFEILD

FBXL18

191

Q96ME1
EIALKLGCLEIRRSY

PTK2

166

Q05397
CLKLDDTVYLRDIAL

FASTKD2

546

Q9NYY8
LRKLFISDGCRYLLS

PRAMEF22

236

A3QJZ6
QERLSIYEARCKGLL

EPPK1

621

P58107
LLEYRTEKEREKLLC

SIN3B

806

O75182
YLCIAAKVRRLVELA

SBNO2

546

Q9Y2G9
SLVSSLCRLVRYLKE

SPICE1

371

Q8N0Z3
LCRLVRYLKESEIQL

SPICE1

376

Q8N0Z3
LRELERYVLSCLRKK

BRD2

696

P25440
CDTLLSRLTELQEKY

CCDC136

536

Q96JN2
LVYRDVLKQLFLCDL

CHST3

186

Q7LGC8
AELCRYLSKVLELRK

C15orf40

101

Q8WUR7
LRTLCVAYKRLIQEE

ATP11A

606

P98196
LDNLSDEYLSCLRKL

TRAF3IP3

491

Q9Y228
CLESVKDLIRYLRHE

TIMELESS

31

Q9UNS1
LLRLCKEASYLVRNS

SHF

336

Q7M4L6
DLCEYHLSLLDEKRL

TTLL11

736

Q8NHH1
CAELVTYDLIKDALL

UCP2

191

P55851
YVCLAIVLSAKDRSL

WDFY3

1136

Q8IZQ1
LRKVICELLETERTY

TIAM1

1041

Q13009
AVCLLYLGKLKDSLR

TRAPPC12

661

Q8WVT3
CYSIDLSERVALKLD

RHBDD2

201

Q6NTF9
LSTFKLYRDKRLCLL

UNC93A

246

Q86WB7
EELISHYRRECLLKL

USP25

921

Q9UHP3
TGKRLCLDLDRYILV

NDST2

301

P52849
RKKIALELSELVVYC

PLCG1

946

P19174
LDKRDCENYITLLER

SEMA7A

121

O75326
EEVKCRLLLALLEYS

PREX2

1241

Q70Z35
KESVIALYRRKCLLE

USP28

941

Q96RU2
KYEDCLIRLLSGLQE

SYMPK

641

Q92797
ELKIRCLDAISSLLY

PSMD5

356

Q16401
IKLEGLCYERQRSEL

THEGL

351

P0DJG4
LVYCSLIKARARELS

UNC13D

671

Q70J99
YDLLLLKCARLFPDS

TRPV4

346

Q9HBA0
LYSSCKSRLLEIVER

TWF1

271

Q12792
LREQLSLESRDKCYL

TMC7

696

Q7Z402
DLKELCALELRDYLG

KLHL38

171

Q2WGJ6
LARKCTELISDIRYK

NEBL

41

O76041