Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintegrin binding

LAMA5 SVEP1 ADAMTS13

7.84e-04175213GO:0005178
DomainVWA

ANTXRL SVEP1

1.79e-0356212PF00092
DomainTSP_1

ADAMTSL4 ADAMTS13

2.26e-0363212PF00090
DomainTSP1

ADAMTSL4 ADAMTS13

2.40e-0365212SM00209
DomainTSP1_rpt

ADAMTSL4 ADAMTS13

2.40e-0365212IPR000884
DomainTSP1

ADAMTSL4 ADAMTS13

2.40e-0365212PS50092
Domain-

ANTXRL SVEP1

3.10e-03742123.40.50.410
DomainVWFA

ANTXRL SVEP1

3.79e-0382212PS50234
DomainVWA

ANTXRL SVEP1

3.97e-0384212SM00327
Domain-

LAMA5 SVEP1

5.05e-03952122.60.120.200
DomainVWF_A

ANTXRL SVEP1

5.47e-0399212IPR002035
DomainGrowth_fac_rcpt_

LAMA5 SVEP1

1.31e-02156212IPR009030
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA5 IRS1

3.46e-0433122M39503
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTSL4 ADAMTS13

4.84e-0439122M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTSL4 ADAMTS13

4.84e-0439122MM15165
Pubmed

Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP.

LAMA5 TH

7.28e-06721228831020
Pubmed

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.

LAMA5 SVEP1

4.15e-051621228179430
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA5 TH

1.12e-042621234189436
Pubmed

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

LAMA5 IRS1

3.24e-044421227534441
Cytoband2q36

IRS1 SPHKAP

5.57e-0682122q36
CytobandEnsembl 112 genes in cytogenetic band chr2q36

IRS1 SPHKAP

6.95e-0485212chr2q36
CytobandEnsembl 112 genes in cytogenetic band chr16p13

MARF1 SRRM2 TNP2

9.32e-04426213chr16p13
CytobandEnsembl 112 genes in cytogenetic band chr9q31

EPB41L4B SVEP1

1.79e-03137212chr9q31
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OAF PXDNL SVEP1

2.68e-05125213b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OAF LAMA5 ADAMTS13

5.29e-051572131e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAF EPB41L4B IRS1

7.18e-05174213a9f34d1237f335d27c5560ff514368f4709f9144
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL11 IRS1 SPHKAP

7.18e-05174213f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAF EPB41L4B IRS1

7.43e-05176213d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OAF PXDNL SVEP1

8.07e-051812139e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRS1 SPHKAP ADAMTS13

8.61e-051852133b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRS1 SPHKAP ADAMTS13

8.61e-051852136712512100ccef456d2e2bd201d0987986c92ac9
ToppCellfacs-Heart-LA-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAF TNP2 SVEP1

8.75e-05186213ed0a91f47e77fe21d4c7678d0f2a7c5f97d63dda
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

OAF IRS1 SPHKAP

9.76e-05193213e2b455387d1de7812305200a2041a0f4759a6f54
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTSL4 TH SVEP1

9.76e-05193213adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

OAF IRS1 SPHKAP

1.01e-04195213c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL4 PXDNL SVEP1

1.04e-041972132744cc94883c5d0424677cf5093bbab622933e9b
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

OAF PXDNL SVEP1

1.07e-04199213c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

OAF NYAP1 IRS1

1.07e-04199213a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

IRS1 SPHKAP ADAMTS13

1.07e-0419921338cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

IRS1 SPHKAP ADAMTS13

1.07e-041992136b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

IRS1 SPHKAP ADAMTS13

1.08e-04200213a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

IRS1 SPHKAP ADAMTS13

1.08e-0420021309537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

IRS1 SPHKAP ADAMTS13

1.08e-0420021302cae2c296a13ad4cbb53bca7a86d64629d67d66
Diseasevon Willebrand factor measurement

EPB41L4B ADAMTS13

6.58e-0456202EFO_0004629
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

IRS1 ADAMTS13

8.85e-0465202DOID:0080208 (biomarker_via_orthology)
DiseaseParkinson's disease (is_marker_for)

SRRM2 TH

9.40e-0467202DOID:14330 (is_marker_for)
Diseaseplatelet component distribution width

NYAP1 LAMA5 SVEP1 IRS1

1.49e-03755204EFO_0007984
Diseasemean arterial pressure

OAF PXDNL SVEP1

4.42e-03499203EFO_0006340
DiseaseLiver carcinoma

TH IRS1 ADAMTS13

4.62e-03507203C2239176
Diseasereticulocyte measurement

NYAP1 KLHL11 MACIR IRS1

4.95e-031053204EFO_0010700
Diseaseurinary albumin to creatinine ratio

OAF SPHKAP

6.47e-03179202EFO_0007778

Protein segments in the cluster

PeptideGeneStartEntry
APCSPRMCLRHSREC

ANTXRL

506

A6NF34
CPTGSRPPDMRACSL

ADAMTSL4

891

Q6UY14
MHQRHPRARCPPLCV

ADAMTS13

1

Q76LX8
GRSHIASPSPCPDRM

OFD1

756

O75665
AEKPRCSSTPCSPMR

MACIR

31

Q96GV9
PACMLPPHLRTTRDS

LAMA5

3326

O15230
HSRSIPMPASRCSPS

IRS1

371

P35568
HAPCMLFARSSPACA

PXDNL

856

A1KZ92
PMPQPRCRATACHVR

KLHL11

646

Q9NVR0
MSCACRRSPRGLSPA

CERK

396

Q8TCT0
CCAHCPNEPSTSPMR

MARF1

101

Q9Y4F3
RRPCLPTAQACTMSH

FAM90A20P

366

A6NIJ5
CAHSRCSPPLSLPMK

EPB41L4B

776

Q9H329
PRTSPCSMISAHSPR

ARHGAP30

1031

Q7Z6I6
CSMISAHSPRPLSCL

ARHGAP30

1036

Q7Z6I6
PHPCRSAMAPRSLSC

NYAP1

71

Q6ZVC0
SPMRPTILHCRCPKN

TNP2

91

Q05952
PSLRSPVCHRQSSMP

SPHKAP

1226

Q2M3C7
CFSRPSMSPTPLDRC

SRRM2

2116

Q9UQ35
SRSGLMPCHPCPRDY

SVEP1

1116

Q4LDE5
PCMLKYCHSRDRPTP

OAF

226

Q86UD1
PDAMPTHACCLSPSL

TMEM39B

256

Q9GZU3
RHASSPMHSPEPDCC

TH

346

P07101