Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentmitochondrial outer membrane translocase complex

TOMM70 HSPA9

4.52e-0422302GO:0005742
GeneOntologyCellularComponentouter mitochondrial membrane protein complex

TOMM70 HSPA9

4.94e-0423302GO:0098799
DomainFYVE

RUFY2 ZFYVE28 MTMR4

1.20e-0529293PF01363
DomainFYVE

RUFY2 ZFYVE28 MTMR4

1.20e-0529293SM00064
DomainZnf_FYVE-rel

RUFY2 ZFYVE28 MTMR4

1.95e-0534293IPR017455
DomainZnf_FYVE

RUFY2 ZFYVE28 MTMR4

2.74e-0538293IPR000306
DomainZF_FYVE

RUFY2 ZFYVE28 MTMR4

3.20e-0540293PS50178
DomainZnf_FYVE_PHD

RUFY2 NSD1 ZFYVE28 MTMR4

7.51e-05147294IPR011011
DomainSpeedy

SPDYC SPDYE16

1.27e-0411292IPR020984
DomainSpy1

SPDYC SPDYE16

1.27e-0411292PF11357
Domain-

RUFY2 NSD1 ZFYVE28 MTMR4

4.86e-034492943.30.40.10
DomainZnf_RING/FYVE/PHD

RUFY2 NSD1 ZFYVE28 MTMR4

5.25e-03459294IPR013083
DomainARM-type_fold

CLASP2 PAIP1 RYR3

1.53e-02339293IPR016024
Pubmed

LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus.

TOMM70 CLASP2 TM9SF3

2.82e-056631336398858
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

RUFY2 TOMM70 PSMD4 CLASP2 DICER1 HSPA9 TM9SF3

3.34e-05106131733845483
Pubmed

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75.

TOMM70 HSPA9

3.44e-051031230590033
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CLASP2 MTMR4 PATL1 DICER1 PAIP1 AFAP1L1

4.03e-0573331634672954
Pubmed

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice.

TOMM70 HSPA9

5.96e-051331219578372
Pubmed

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

SPDYC SPDYE16

5.96e-051331215611625
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

NSD1 PSMD4 DICER1 PAIP1

6.21e-0524231434011540
Pubmed

Characterization of a new family of cyclin-dependent kinase activators.

SPDYC SPDYE16

1.04e-041731215574121
Pubmed

Wilms Tumor Predisposition

NSD1 DICER1

1.17e-041831220301471
Pubmed

NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity.

PSMD4 HSPA9

1.76e-042231238303107
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

TOMM70 PSMD4 MTMR4 PIPSL DICER1 TM9SF3

1.92e-0497431628675297
Pubmed

In vivo validation of late-onset Alzheimer's disease genetic risk factors.

CLASP2 MTMR4

2.28e-042531238687251
Pubmed

Proteomic analysis of the NOS2 interactome in human airway epithelial cells.

PSMD4 DICER1 HSPA9

2.53e-0413831323438482
Pubmed

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

PSMD4 PAIP1 HSPA9

3.11e-0414831335676246
Pubmed

Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development.

ALDH1L1 DICER1

3.52e-043131223895693
Pubmed

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.

TOMM70 HSPA9 TM9SF3

3.91e-0416031323798571
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

CPEB2 CLASP2 PATL1 DICER1 PARP12

4.16e-0472331534133714
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

PSMD4 HSPA9 RYR3

6.54e-0419131320195357
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

CPEB2 PAIP1 HSPA9 TM9SF3

6.99e-0445731432344865
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

CPEB2 PATL1 DICER1 PARP12

7.28e-0446231431138677
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

TOMM70 PSMD4 PIPSL HSPA9 KLHL13 TM9SF3

7.46e-04125731637317656
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

PSMD4 PATL1 DICER1 HSPA9

7.70e-0446931437314180
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

RUFY2 ZFYVE28 MTMR4

6.88e-063122381
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_500

NSD1 CLASP2 PAIP1 TM9SF3

6.22e-05165284DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

RUFY2 NSD1 CLASP2 PAIP1 TM9SF3

6.44e-05330285DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

RUFY2 CPEB2 NSD1 CLASP2 PAIP1 RYR3 TM9SF3

7.15e-05818287DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

RUFY2 NSD1 CLASP2 PAIP1 TM9SF3

1.09e-04369285DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_100

NSD1 COLEC11 PAIP1

1.76e-0483283gudmap_developingLowerUrinaryTract_e14.5_ bladder_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500

CPEB2 NSD1 CLASP2 PAIP1 TM9SF3

2.15e-04427285DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500

NSD1 COLEC11 PAIP1 TM9SF3

2.28e-04231284gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500

CPEB2 COLEC11 RYR3

3.52e-04105283gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k2

Protein segments in the cluster

PeptideGeneStartEntry
CMLANGKLDEDYEEE

DICER1

1406

Q9UPY3
SIKLDSEEDMPFEDC

NSD1

446

Q96L73
DPDAELACSMQYDDQ

ZFYVE28

326

Q9HCC9
MFRYESLEDCPLDED

PATL1

1

Q86TB9
DDLDESCMETLDPKF

DSG4

826

Q86SJ6
MEEFKDQLPADECNK

HSPA9

596

P38646
EPPMDYEDDFTCLKE

MTMR4

1061

Q9NYA4
DEMDPEIEEAYEKFC

PAIP1

456

Q9H074
KEEDDYDVMQDPEFL

PIPSL

806

A2A3N6
DLDNMELIEEAYCNP

PARP12

311

Q9H0J9
PDENENLKECYLMEN

PLA2G4E

756

Q3MJ16
CMVEIVQKYDPDKDE

KLHL13

601

Q9P2N7
EVKPYVLDDQMCDEC

CPEB2

516

Q7Z5Q1
GEPNNAYDEEDCVEM

COLEC11

231

Q9BWP8
KEEDDYDVMQDPEFL

PSMD4

321

P55036
DPFEKCMQDPDYEQL

IL4I1

31

Q96RQ9
MEAEDEDEKYLQECL

RUFY2

411

Q8WXA3
DDYDADCEDIDCKLM

TAF1L

141

Q8IZX4
NMPYDLCDDEQTLDC

PPP1R16A

171

Q96I34
FDCDLSDLRDMPEDD

AFAP1L1

76

Q8TED9
ELCDGLELENEDVYM

ALDH1L1

366

O75891
LKEAMFDDDADQFPD

CLASP2

1036

O75122
YNKSEDDDEPDMKCD

RYR3

4696

Q15413
ALYLANDMEEDDEDP

SPDYE16

211

A6NNV3
ALYLANDMEEDDEDP

SPDYE18

251

P0DV79
YLANDMEEDLEGPKC

SPDYC

116

Q5MJ68
LEKPFEYNECMEALD

RBAK

201

Q9NYW8
DVYPQMCFDEDINDK

SEPTIN12

221

Q8IYM1
DEMYDKCIDLEPDNA

TOMM70

496

O94826
LDDMISEPMDENCYE

TRAT1

66

Q6PIZ9
DVMPATYCEIDLDKE

TM9SF3

101

Q9HD45
ALYLANDMEEDDEDP

nan

211

A6NJR5