Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	beta-catenin binding	MED12L MET TJP1 MED12	1.81e-04	120	47	4	GO:0008013
GeneOntologyMolecularFunction	histone acetyltransferase activity	TAF9 PHF10 KAT14	2.35e-04	51	47	3	GO:0004402
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	TAF9 PHF10 KAT14	2.94e-04	55	47	3	GO:0061733
GeneOntologyMolecularFunction	semaphorin receptor activity	MET PLXNB1	3.53e-04	12	47	2	GO:0017154
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	TAF9 PHF10 KAT14	3.81e-04	60	47	3	GO:0034212
GeneOntologyMolecularFunction	N-acetyltransferase activity	TAF9 PHF10 KAT14	8.22e-04	78	47	3	GO:0008080
GeneOntologyMolecularFunction	N-acyltransferase activity	TAF9 PHF10 KAT14	1.78e-03	102	47	3	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	TAF9 PHF10 KAT14	1.88e-03	104	47	3	GO:0016407
GeneOntologyMolecularFunction	adenylyltransferase activity	COASY TENT5D	2.41e-03	31	47	2	GO:0070566
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	PAK1 FUZ NDNF MET ARHGAP32 PLXNB1 STAU2	1.19e-04	494	47	7	GO:0031346
GeneOntologyBiologicalProcess	regulation of anatomical structure morphogenesis	TAOK2 PAK1 FUZ JCAD MET ARHGAP32 TJP1 SHANK3 PLXNB1 STAU2	1.41e-04	1090	47	10	GO:0022603
GeneOntologyBiologicalProcess	positive regulation of neurogenesis	PAK1 MET ARHGAP32 SHANK3 PLXNB1 STAU2	1.45e-04	354	47	6	GO:0050769
GeneOntologyBiologicalProcess	negative regulation of actin filament bundle assembly	MET TJP1 SHANK3	1.47e-04	45	47	3	GO:0032232
GeneOntologyBiologicalProcess	regulation of actin filament bundle assembly	PAK1 MET TJP1 SHANK3	1.76e-04	123	47	4	GO:0032231
GeneOntologyBiologicalProcess	observational learning	PAK1 SHANK3	1.81e-04	9	47	2	GO:0098597
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	TAOK2 PAK1 MET TJP1 SHANK3 STAU2	2.26e-04	384	47	6	GO:0032956
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	TAOK2 PAK1 MET ARHGAP32 SHANK3 PLXNB1 MYPN STAU2	2.59e-04	748	47	8	GO:0048667
GeneOntologyBiologicalProcess	DNA damage response	TAOK2 PAK1 TDP1 TAF9 UBE2T PHF10 RADX NUPR2 PHF13	2.70e-04	959	47	9	GO:0006974
GeneOntologyBiologicalProcess	embryonic neurocranium morphogenesis	FUZ MED12	2.76e-04	11	47	2	GO:0048702
GeneOntologyBiologicalProcess	heart development	PAK1 TRAF3IP2 FUZ MET ERBB4 FBN1 CCM2L MED12	2.80e-04	757	47	8	GO:0007507
GeneOntologyBiologicalProcess	circulatory system development	PAK1 TRAF3IP2 FUZ JCAD NDNF MET ERBB4 FBN1 CCM2L TJP1 MED12	3.14e-04	1442	47	11	GO:0072359
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	TAOK2 PAK1 MET TJP1 SHANK3 PLXNB1 STAU2	3.14e-04	579	47	7	GO:0051493
GeneOntologyBiologicalProcess	hepatocyte growth factor receptor signaling pathway	PAK1 MET	3.31e-04	12	47	2	GO:0048012
GeneOntologyBiologicalProcess	positive regulation of nervous system development	PAK1 MET ARHGAP32 SHANK3 PLXNB1 STAU2	3.55e-04	418	47	6	GO:0051962
GeneOntologyBiologicalProcess	neuron projection morphogenesis	TAOK2 PAK1 MET ARHGAP32 SHANK3 PLXNB1 MYPN STAU2	4.13e-04	802	47	8	GO:0048812
GeneOntologyBiologicalProcess	regulation of neuron projection development	PAK1 NDNF MET ARHGAP32 SHANK3 PLXNB1 STAU2	4.39e-04	612	47	7	GO:0010975
GeneOntologyBiologicalProcess	positive regulation of cell development	PAK1 MET ARHGAP32 PHF10 SHANK3 PLXNB1 STAU2	4.47e-04	614	47	7	GO:0010720
GeneOntologyBiologicalProcess	regulation of actin filament-based process	TAOK2 PAK1 MET TJP1 SHANK3 STAU2	4.55e-04	438	47	6	GO:0032970
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	TAOK2 PAK1 MET ARHGAP32 SHANK3 PLXNB1 MYPN STAU2	4.75e-04	819	47	8	GO:0120039
GeneOntologyBiologicalProcess	regulation of long-term synaptic potentiation	PAK1 PDE9A SHANK3	4.80e-04	67	47	3	GO:1900271
GeneOntologyBiologicalProcess	cell projection morphogenesis	TAOK2 PAK1 MET ARHGAP32 SHANK3 PLXNB1 MYPN STAU2	5.02e-04	826	47	8	GO:0048858
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	PAK1 FUZ NDNF MET ARHGAP32 SHANK3 PLXNB1 STAU2	5.88e-04	846	47	8	GO:0120035
GeneOntologyBiologicalProcess	regulation of cell projection organization	PAK1 FUZ NDNF MET ARHGAP32 SHANK3 PLXNB1 STAU2	6.71e-04	863	47	8	GO:0031344
MousePheno	abnormal habituation to a novel odor	ARHGAP32 SHANK3	2.27e-05	3	39	2	MP:0011622
MousePheno	abnormal habituation	TAOK2 ARHGAP32 SHANK3	3.90e-05	24	39	3	MP:0011617
MousePheno	abnormal nonassociative learning	TAOK2 ARHGAP32 SHANK3	5.61e-05	27	39	3	MP:0011616
MousePheno	diaphragmatic hernia	FUZ MET FBN1	6.98e-05	29	39	3	MP:0003924
Domain	Mediator_Med12_catenin-bd	MED12L MED12	6.47e-06	2	48	2	IPR021989
Domain	Med12-PQL	MED12L MED12	6.47e-06	2	48	2	PF12144
Domain	Med12-LCEWAV	MED12L MED12	6.47e-06	2	48	2	PF12145
Domain	Mediator_Med12	MED12L MED12	6.47e-06	2	48	2	IPR019035
Domain	Med12	MED12L MED12	6.47e-06	2	48	2	SM01281
Domain	Med12	MED12L MED12	6.47e-06	2	48	2	PF09497
Domain	Mediator_Med12_LCEWAV	MED12L MED12	6.47e-06	2	48	2	IPR021990
Domain	DSRM	NKRF STAU2	1.08e-03	19	48	2	SM00358
Domain	dsrm	NKRF STAU2	1.19e-03	20	48	2	PF00035
Domain	IPT	MET PLXNB1	2.18e-03	27	48	2	SM00429
Domain	-	NKRF STAU2	2.18e-03	27	48	2	3.30.160.20
Domain	dsRBD_dom	NKRF STAU2	2.34e-03	28	48	2	IPR014720
Domain	Ig_E-set	MET ARRDC3 PLXNB1	2.42e-03	104	48	3	IPR014756
Domain	TIG	MET PLXNB1	2.87e-03	31	48	2	PF01833
Domain	SEMA	MET PLXNB1	2.87e-03	31	48	2	PS51004
Domain	Sema	MET PLXNB1	2.87e-03	31	48	2	SM00630
Domain	Semap_dom	MET PLXNB1	2.87e-03	31	48	2	IPR001627
Domain	Sema	MET PLXNB1	2.87e-03	31	48	2	PF01403
Domain	Plexin_repeat	MET PLXNB1	3.05e-03	32	48	2	IPR002165
Domain	PSI	MET PLXNB1	3.05e-03	32	48	2	PF01437
Domain	IPT	MET PLXNB1	3.05e-03	32	48	2	IPR002909
Domain	PSI	MET PLXNB1	5.71e-03	44	48	2	IPR016201
Domain	PSI	MET PLXNB1	6.23e-03	46	48	2	SM00423
Domain	PX	ARHGAP32 PIK3C2B	7.04e-03	49	48	2	PF00787
Domain	PX	ARHGAP32 PIK3C2B	7.32e-03	50	48	2	PS50195
Domain	-	ARHGAP32 PIK3C2B	7.61e-03	51	48	2	3.30.1520.10
Domain	Phox	ARHGAP32 PIK3C2B	7.90e-03	52	48	2	IPR001683
Pathway	REACTOME_SEMA4D_MEDIATED_INHIBITION_OF_CELL_ATTACHMENT_AND_MIGRATION	MET PLXNB1	1.22e-04	8	30	2	M27325
Pathway	REACTOME_SEMA4D_MEDIATED_INHIBITION_OF_CELL_ATTACHMENT_AND_MIGRATION	MET PLXNB1	1.22e-04	8	30	2	MM15045
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PAK1 MET PLXNB1	1.69e-04	51	30	3	MM14967
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PAK1 MET PLXNB1	3.32e-04	64	30	3	M7923
Pathway	SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES	PAK1 MET ERBB4	3.80e-04	67	30	3	M295
Pathway	KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION	PAK1 MET TJP1	3.97e-04	68	30	3	M16848
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	MET PLXNB1	4.52e-04	15	30	2	MM15037
Pubmed	SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCε-dependent Pathway.	TJP1 SHANK3	1.87e-06	2	48	2	28906292
Pubmed	Co-expression of plexin-B1 and Met in human breast and ovary tumours enhances the risk of progression.	MET PLXNB1	1.87e-06	2	48	2	19940359
Pubmed	PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling.	PAK1 MET	1.87e-06	2	48	2	22105362
Pubmed	Plexin B1 suppresses c-Met in melanoma: a role for plexin B1 as a tumor-suppressor protein through regulation of c-Met.	MET PLXNB1	1.87e-06	2	48	2	20164843
Pubmed	PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition.	PAK1 MET	1.87e-06	2	48	2	25074413
Pubmed	Hepatocyte growth factor, a determinant of airspace homeostasis in the murine lung.	MET FBN1	5.59e-06	3	48	2	23459311
Pubmed	Frequent gene amplification predicts poor prognosis in gastric cancer.	MET ERBB4	5.59e-06	3	48	2	22606006
Pubmed	Sema4D induces angiogenesis through Met recruitment by Plexin B1.	MET PLXNB1	5.59e-06	3	48	2	15632204
Pubmed	A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions.	JCAD TJP1	5.59e-06	3	48	2	21884682
Pubmed	The semaphorin 4D receptor controls invasive growth by coupling with Met.	MET PLXNB1	5.59e-06	3	48	2	12198496
Pubmed	High incidence of ErbB3, ErbB4, and MET expression in ovarian cancer.	MET ERBB4	5.59e-06	3	48	2	24901400
Pubmed	Transactivation of Met signalling by semaphorin4D in human placenta: implications for the pathogenesis of preeclampsia.	MET PLXNB1	5.59e-06	3	48	2	29939944
Pubmed	Effect of cancer-associated mutations in the PlexinB1 gene.	MET PLXNB1	1.12e-05	4	48	2	22404908
Pubmed	ErbB-2 and met reciprocally regulate cellular signaling via plexin-B1.	MET PLXNB1	1.12e-05	4	48	2	18025083
Pubmed	Microtubule dynamics control HGF-induced lung endothelial barrier enhancement.	PAK1 MET	1.86e-05	5	48	2	25198505
Pubmed	Plexin-B3 is a functional receptor for semaphorin 5A.	MET PLXNB1	1.86e-05	5	48	2	15218527
Pubmed	Interplay between scatter factor receptors and B plexins controls invasive growth.	MET PLXNB1	1.86e-05	5	48	2	15184888
Pubmed	The activity of the plexin-A1 receptor is regulated by Rac.	PAK1 PLXNB1	1.86e-05	5	48	2	15187088
Pubmed	Human transcription factor protein interaction networks.	TIMM50 ARHGAP32 ZFHX3 FBN1 TAF9 PHF10 KAT14 RADX NKRF STAU2	2.09e-05	1429	48	10	35140242
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TAOK2 TIMM50 JCAD MET ARHGAP32 ERBB4 TJP1 SHANK3 STAU2	2.23e-05	1139	48	9	36417873
Pubmed	Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3.	MED12L MED12	2.79e-05	6	48	2	11524702
Pubmed	Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.	TJP1 STAU2	3.90e-05	7	48	2	22902295
Pubmed	p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling.	MET PLXNB1	5.19e-05	8	48	2	16188938
Pubmed	Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells.	MET PLXNB1	8.33e-05	10	48	2	12730235
Pubmed	A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study.	ERBB4 FBN1	1.02e-04	11	48	2	17903305
Pubmed	Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.	ERBB4 PLXNB1	1.02e-04	11	48	2	25315821
Pubmed	Endothelial cell specification in the somite is compromised in Pax3-positive progenitors of Foxc1/2 conditional mutants, with loss of forelimb myogenesis.	MET TJP1	1.02e-04	11	48	2	26839363
Pubmed	Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.	PAK1 PLXNB1	1.22e-04	12	48	2	12123608
Pubmed	An asymmetrically localized Staufen2-dependent RNA complex regulates maintenance of mammalian neural stem cells.	TJP1 STAU2	1.22e-04	12	48	2	22902294
Pubmed	Translational animal models of autism and neurodevelopmental disorders.	MET SHANK3	1.68e-04	14	48	2	23226954
Pubmed	Pax3:Foxc2 reciprocal repression in the somite modulates muscular versus vascular cell fate choice in multipotent progenitors.	MET TJP1	1.94e-04	15	48	2	20059958
Pubmed	Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors.	SLC12A9 TJP1	2.50e-04	17	48	2	11060040
Pubmed	Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development.	MET TJP1	2.81e-04	18	48	2	14607778
Pubmed	Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia.	MED12L MED12	2.81e-04	18	48	2	23575864
Pubmed	Tbx1 and Foxi3 genetically interact in the pharyngeal pouch endoderm in a mouse model for 22q11.2 deletion syndrome.	GCM2 TJP1	2.81e-04	18	48	2	31412026
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PAK1 JCAD ARHGAP32 ERBB4 ARRDC3	3.12e-04	430	48	5	35044719
Pubmed	STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.	TAF9 MED12	3.49e-04	20	48	2	17967894
Pubmed	Genome-wide association studies identify four ER negative-specific breast cancer risk loci.	UBE2T PIK3C2B	3.85e-04	21	48	2	23535733
Pubmed	E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions.	PAK1 TJP1	3.85e-04	21	48	2	15775979
Pubmed	Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney.	MET PLXNB1	4.63e-04	23	48	2	21035938
Pubmed	Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.	TJP1 SHANK3	4.63e-04	23	48	2	16637659
Pubmed	Par3 is essential for the establishment of planar cell polarity of inner ear hair cells.	PAK1 TJP1	5.05e-04	24	48	2	30814219
Pubmed	PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation.	TJP1 RAMAC	5.05e-04	24	48	2	24710276
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TAOK2 TIMM50 TAF9 TJP1 PHF10 NKRF RAMAC STAU2	5.29e-04	1371	48	8	36244648
Pubmed	The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.	TAF9 MED12	5.48e-04	25	48	2	19240132
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	MET ERBB4	5.48e-04	25	48	2	15254900
Pubmed	Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.	PAK1 TJP1	5.48e-04	25	48	2	31410202
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TIMM50 ZFHX3 ERBB4 TAF9 PHF10 KAT14 NKRF	8.02e-04	1116	48	7	31753913
Pubmed	Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation.	ERBB4 SHANK3	8.45e-04	31	48	2	19736351
Pubmed	The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.	PAK1 ERBB4 PIK3C2B	8.52e-04	134	48	3	24658140
Pubmed	Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice.	PAK1 TJP1	9.01e-04	32	48	2	26184908
Pubmed	Protein microarrays for the identification of praja1 e3 ubiquitin ligase substrates.	COASY TAF9	1.02e-03	34	48	2	21461837
Pubmed	A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease.	UBE2T HYDIN	1.08e-03	35	48	2	23936387
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TIMM50 JCAD ARHGAP32 ERBB4 PIK3C2B TJP1	1.14e-03	861	48	6	36931259
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	FBN1 TJP1	1.20e-03	37	48	2	34323105
Pubmed	Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.	MET ZFHX3	1.34e-03	39	48	2	19010793
Pubmed	Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.	ZFHX3 SLC12A9	1.34e-03	39	48	2	21347282
Interaction	TRIM27 interactions	PAK1 ZFHX3 UBE2T MAT2B PIK3C2B KAT14 SHANK3 RAMAC	1.89e-05	514	46	8	int:TRIM27
Interaction	PLCG1 interactions	PAK1 MET ARHGAP32 ERBB4 FEM1A PLXNB1	2.88e-05	264	46	6	int:PLCG1
GeneFamily	Cyclins\|Mediator complex	MED12L MED12	1.19e-03	33	28	2	1061
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	JCAD CCM2L PIK3C2B TJP1 SHANK3	1.52e-06	182	48	5	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	JCAD CCM2L PIK3C2B TJP1 SHANK3	1.88e-06	190	48	5	5130fb325f80f591b9b36beacb8072c4472304f2
ToppCell	PND01-03-samps-Endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	JCAD CCM2L PIK3C2B TJP1 SHANK3	1.88e-06	190	48	5	1357bd4527399d7013ee33272bda7453f472999a
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JCAD ARRDC3 CCM2L TJP1 SHANK3	1.93e-06	191	48	5	2f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	JCAD CCM2L PIK3C2B TJP1 SHANK3	1.93e-06	191	48	5	44c596984c6196f6014e0e405dbe5560841e54ff
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-tip_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	JCAD FBN1 CCM2L TJP1 SHANK3	1.93e-06	191	48	5	cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCell	E16.5-samps-Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	JCAD CCM2L PIK3C2B TJP1 SHANK3	1.93e-06	191	48	5	e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175\|Adult / Lineage, Cell type, age group and donor	DCBLD1 MET ERBB4 UBE2T	2.06e-05	150	48	4	b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MET ERBB4 GCM2 PLXNB1	2.46e-05	157	48	4	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	2.79e-05	162	48	4	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	MED12L JCAD FBN1 PLXNB1	2.99e-05	165	48	4	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TAOK2 FBN1 PIK3C2B SHANK3	3.06e-05	166	48	4	9d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CCM2L PIK3C2B TJP1 SHANK3	3.44e-05	171	48	4	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	3.52e-05	172	48	4	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	3.76e-05	175	48	4	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	3.94e-05	177	48	4	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	4.11e-05	179	48	4	8f9e538c822940785130297712b75131812a4603
ToppCell	PBMC-Mild-Hematopoietic-HSPC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MED12L FBN1 TPSG1 SHANK3	4.11e-05	179	48	4	2f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCell	COVID-19_Mild-Hematopoietic_SC-HSPC\|COVID-19_Mild / Disease group, lineage and cell class	MED12L FBN1 TPSG1 SHANK3	4.11e-05	179	48	4	19fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MED12L FBN1 TPSG1 SHANK3	4.11e-05	179	48	4	4bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MED12L FBN1 TPSG1 SHANK3	4.11e-05	179	48	4	3e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCell	COVID-19_Mild-Hematopoietic_SC\|COVID-19_Mild / Disease group, lineage and cell class	MED12L FBN1 TPSG1 SHANK3	4.11e-05	179	48	4	50a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MED12L FBN1 TPSG1 SHANK3	4.29e-05	181	48	4	54a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCell	PBMC-Mild-Hematopoietic-HSPC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MED12L FBN1 TPSG1 SHANK3	4.29e-05	181	48	4	5b84625b1d3737708001b64f6da9360330d39a27
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MED12L FBN1 TPSG1 SHANK3	4.29e-05	181	48	4	e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	JCAD CCM2L TJP1 SHANK3	4.39e-05	182	48	4	7af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCell	E18.5-samps-Endothelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	JCAD CCM2L TJP1 SHANK3	4.39e-05	182	48	4	e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Interneuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	MET ERBB4 ARRDC3	4.54e-05	64	48	3	fefabdf8d72a8f3caf78eb79d759edb475bdb2ad
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	4.67e-05	185	48	4	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAOK2 JCAD PIK3C2B TJP1	4.77e-05	186	48	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	4.77e-05	186	48	4	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	JCAD CCM2L PIK3C2B SHANK3	4.87e-05	187	48	4	a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	JCAD CCM2L PIK3C2B SHANK3	4.87e-05	187	48	4	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	JCAD CCM2L PIK3C2B SHANK3	4.98e-05	188	48	4	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	JCAD CCM2L PIK3C2B SHANK3	4.98e-05	188	48	4	b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PIK3C2B SHANK3 MED12 PHF13	5.08e-05	189	48	4	bccb3481ffed597c845fe860da658505316105b5
ToppCell	PND07-28-samps-Endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CCM2L PIK3C2B TJP1 SHANK3	5.08e-05	189	48	4	eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	5.08e-05	189	48	4	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CCM2L PIK3C2B TJP1 SHANK3	5.08e-05	189	48	4	d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	5.18e-05	190	48	4	f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MET CCM2L PIK3C2B SHANK3	5.18e-05	190	48	4	1307688255a1250fa300edf2c41f1affe31dcc98
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	JCAD CCM2L PIK3C2B SHANK3	5.18e-05	190	48	4	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MET ERBB4 PDE9A HYDIN	5.18e-05	190	48	4	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.29e-05	191	48	4	f663131a4810584c5854bd64ee7991a237b7707f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 CCM2L PIK3C2B SHANK3	5.29e-05	191	48	4	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD PIK3C2B TJP1 SHANK3	5.40e-05	192	48	4	c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 CCM2L PIK3C2B SHANK3	5.40e-05	192	48	4	1ee4783051ec94ea94600f040edcb385fc4289f1
ToppCell	LPS-IL1RA+antiTNF-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD PIK3C2B TJP1 SHANK3	5.40e-05	192	48	4	04f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD CCM2L PIK3C2B SHANK3	5.40e-05	192	48	4	5a0615fdc217554ccd611504b16e5d97628e207d
ToppCell	Endothelial-Endothelial-B\|Endothelial / shred on cell class and cell subclass (v4)	DCBLD1 JCAD ZFHX3 ARRDC3	5.40e-05	192	48	4	f8d7bd81e031d09a557722627c2f6180811cc6ab
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDNF MET FBN1 PLXNB1	5.40e-05	192	48	4	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.40e-05	192	48	4	28eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PIK3C2B TJP1 SHANK3	5.51e-05	193	48	4	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 CCM2L PIK3C2B SHANK3	5.51e-05	193	48	4	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD PIK3C2B TJP1 SHANK3	5.51e-05	193	48	4	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PIK3C2B TJP1 SHANK3	5.51e-05	193	48	4	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 CCM2L PIK3C2B SHANK3	5.51e-05	193	48	4	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD PIK3C2B TJP1 SHANK3	5.51e-05	193	48	4	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	facs-Heart-RA-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCBLD1 JCAD PIK3C2B SHANK3	5.51e-05	193	48	4	e7805e866339f676e3f770980c2e0a649eff472e
ToppCell	facs-Heart-RA-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCBLD1 JCAD PIK3C2B SHANK3	5.51e-05	193	48	4	1ad941098f1a44a46c2f6ebff32a98ada32c80ab
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PIK3C2B TJP1 SHANK3	5.51e-05	193	48	4	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	5.62e-05	194	48	4	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DCBLD1 JCAD ARRDC3 TJP1	5.62e-05	194	48	4	50fa7c7940b113427c87fbdb9057fef8e1ce52c5
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DCBLD1 JCAD ARRDC3 TJP1	5.62e-05	194	48	4	fc40ab57be3a15c043e3414c2c678c1dc52207c8
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD PIK3C2B TJP1 SHANK3	5.62e-05	194	48	4	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.62e-05	194	48	4	b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.62e-05	194	48	4	f76808666fb875fc787751cbfd924d9be20a8192
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCBLD1 JCAD TJP1 SHANK3	5.62e-05	194	48	4	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.62e-05	194	48	4	74a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 CCM2L PIK3C2B SHANK3	5.62e-05	194	48	4	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD PIK3C2B TJP1 SHANK3	5.62e-05	194	48	4	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.62e-05	194	48	4	f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.62e-05	194	48	4	a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell	facs-Heart-RA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCBLD1 JCAD PIK3C2B SHANK3	5.73e-05	195	48	4	f4fdcc0b851392086e9618e76ee6a0b540d5fb3c
ToppCell	3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 ARRDC3 TDP1 SHANK3	5.73e-05	195	48	4	6a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAOK2 JCAD TJP1 SHANK3	5.73e-05	195	48	4	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAOK2 DCBLD1 PIK3C2B TJP1	5.73e-05	195	48	4	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 CCM2L PIK3C2B SHANK3	5.73e-05	195	48	4	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	ae46d4b00be92e64e46252dcc156161b171eded4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	Fetal_29-31_weeks-Endothelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	3981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	PCW_10-12-Endothelial-Endothelial_mature\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	481d79bdaec069ad2746a28d39eeee8d3edf7305
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	22767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	5.85e-05	196	48	4	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	tumor_Lung-Endothelial_cells-Tip-like_ECs\|tumor_Lung / Location, Cell class and cell subclass	JCAD CCM2L TJP1 SHANK3	5.97e-05	197	48	4	353b76ca3e2aa4b8f51396e7121c4baa114083a0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	6.08e-05	198	48	4	07701c73137947ed4a27e225975329235bbb8734
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	JCAD CCM2L PIK3C2B SHANK3	6.08e-05	198	48	4	8689090bce9ab6e8f122426a404037e572c6713b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	6.08e-05	198	48	4	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	6.08e-05	198	48	4	8e45551224fbb30c0658ad47dd98335ecf165437
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD CCM2L PIK3C2B SHANK3	6.08e-05	198	48	4	953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DCBLD1 JCAD CCM2L SHANK3	6.20e-05	199	48	4	d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD FBN1 CCM2L SHANK3	6.20e-05	199	48	4	a8f2eb00c3e4267a174bc9eff307dc2e5d18c76e
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DCBLD1 JCAD CCM2L SHANK3	6.20e-05	199	48	4	cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCell	wk_20-22-Endothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	JCAD CCM2L TJP1 SHANK3	6.20e-05	199	48	4	07be9509a8ec9c9a7d721912d77c20e841f49808
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	JCAD CCM2L TJP1 SHANK3	6.33e-05	200	48	4	77ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
Drug	fusarin C	MET ARHGAP32 TDP1	4.89e-07	8	48	3	CID006435894
Disease	Malignant neoplasm of kidney	RASSF5 MET UBE2T	5.13e-05	45	47	3	C0740457
Disease	autism spectrum disorder (implicated_via_orthology)	TAOK2 MET ARHGAP32 SHANK3	1.02e-04	152	47	4	DOID:0060041 (implicated_via_orthology)
Disease	pulse pressure measurement	JCAD MET ZFHX3 FBN1 COASY HYDIN WBP1L MYPN PHF13	3.03e-04	1392	47	9	EFO_0005763
Disease	obesity (implicated_via_orthology)	MED12L ZFHX3 MED12 PLXNB1	3.82e-04	215	47	4	DOID:9970 (implicated_via_orthology)
Disease	haptoglobin measurement	ZFHX3 HYDIN	5.12e-04	21	47	2	EFO_0004640
Disease	obsolete Mendelian syndromes with cleft lip/palate	PAK1 JCAD	6.15e-04	23	47	2	MONDO_0015335
Disease	FEV/FEC ratio	DCBLD1 JCAD RASSF5 MET ZFHX3 FBN1 PDE9A PHF13	6.51e-04	1228	47	8	EFO_0004713
Disease	melanoma	PAK1 DCBLD1 MET ERBB4	6.54e-04	248	47	4	C0025202
Disease	myeloid white cell count	MED12L JCAD RASSF5 MET ZFHX3 PLXNB1 TREML2	6.61e-04	937	47	7	EFO_0007988
Disease	Neoplasm of the genitourinary tract	MET ZFHX3	6.70e-04	24	47	2	cv:C0042065
Disease	complex trait	TAOK2 DCBLD1 SLC12A9 PCSK9	9.10e-04	271	47	4	EFO_0010578
Disease	peak expiratory flow	JCAD PIK3C2B MYPN STAU2 PHF13	1.15e-03	498	47	5	EFO_0009718
Disease	cervical cancer (is_marker_for)	ZFHX3 ERBB4	1.51e-03	36	47	2	DOID:4362 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EYLVPQAFNIPPPIY	ERBB4	1021	Q15303
SMPLYPPDYLIDPQI	CCM2L	41	Q9NUG4
FRFLPPPLYSEIDPN	ARRDC3	386	Q96B67
YQEYLKRPPESPPIV	RAMAC	26	Q9BTL3
RPYPLLLDPEPPRYL	RASSF5	11	Q8WWW0
DEPRDTVPKPPLYCY	RADX	81	Q6NSI4
RSYYLQPLPLPPEEE	MED12L	1721	Q86YW9
PYREEDIPAPLNLYG	MAT2B	146	Q9NZL9
YRSPPQNIPNPYLED	JCAD	346	Q9P266
ITPPRYRADEYQPPD	PCSK9	161	Q8NBP7
PPAPLILPSSLDYQY	PLXNB1	881	O43157
ARPPPPISYEEELYD	NUPR2	16	A6NF83
PRRDVPTYPKYLLSP	PDE9A	236	O76083
TPEPDAPLDYCYVRP	KAT14	631	Q9H8E8
QPYPELPYDPRVDVT	NDNF	171	Q8TB73
AYYLEPLPLPPEDEE	MED12	1736	Q93074
RNTCYPEDIPPYPTI	ARHGAP32	1566	A7KAX9
NDPDPYVKIYLLPDP	PIK3C2B	1536	O00750
EPPYLNENPLRALYL	PAK1	461	Q13153
YLPLNTALYEPPLDP	PHF10	276	Q8WUB8
PRNPGEKLPPELYEY	HYDIN	1891	Q4G0P3
PVEYLYPSREPPRVL	FBN1	431	P35555
YYRPDLTIPEIPPKR	BRAWNIN	31	Q69YU5
LPKPEPPQLVLAYDY	FEM1A	336	Q9BSK4
RHEYALPLAPPEPEY	DCBLD1	586	Q8N8Z6
RFLFPEYILDPEPQP	NOA1	71	Q8NC60
SLPPQTARDYPVYLP	FUZ	211	Q9BT04
RLLQPEYCPDPLYEV	MET	1301	P08581
LIKPYSGPRLPPDRY	TAF9	106	Q16594
YTREGEPLPPPYSLR	TPSG1	166	Q9NRR2
RDPPGRPEPYVEVYL	TREML2	306	Q5T2D2
YIYAPLKEIPPADIP	NKRF	216	O15226
IYLPRPPCSYELANP	GCM2	266	O75603
AAEARYPIYVIPEPP	TENT5D	356	Q8NEK8
YDDPYQPEITPSPLQ	TAOK2	426	Q9UL54
SEPYPSQLLKPIPEY	TRAF3IP2	21	O43734
RPPYERPELPTCLYV	COASY	346	Q13057
YIPYPKEELPLRSSP	PHF13	41	Q86YI8
PVPYDLPPELYGSKD	TDP1	571	Q9NUW8
SPCLLPDPLQEPYYQ	TIMM50	131	Q3ZCQ8
AIYRPLDPKPFPNYR	STAU2	111	Q9NUL3
EEEDNLPFPYPKYPR	SPEM2	186	Q0P670
EYPPNLDTPLPYLEF	SHANK3	76	Q9BYB0
PPADPARYPRYLALL	SLC12A9	876	Q9BXP2
YPFEPPQIRFLTPIY	UBE2T	61	Q9NPD8
PDKEPNLTYEPQLPY	TJP1	1031	Q07157
PNYLLPPYEEVVNRP	WBP1L	101	Q9NX94
YDKLYPLRPQTPEPP	ZFHX3	2026	Q15911
PSSLYYEEPLGQPPR	MYPN	256	Q86TC9