Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL9A3 COL12A1 FMOD LAMA1 LAMA2 COL25A1 EDIL3 LTBP4 SSPOP MUC5AC AGRN	2.63e-10	188	81	11	GO:0005201
GeneOntologyMolecularFunction	structural molecule activity	COL9A3 COL12A1 FMOD MAP1A LAMA1 LAMA2 COL25A1 EDIL3 LTBP4 SSPOP MUC5AC AGRN BICD1	5.73e-05	891	81	13	GO:0005198
GeneOntologyMolecularFunction	calcium ion binding	MCTP1 MEGF8 LRP4 ADAMTS13 VWCE EDIL3 LTBP4 AGRN SVEP1 NOTCH4 CRB2	2.13e-04	749	81	11	GO:0005509
GeneOntologyBiologicalProcess	circulatory system development	DNAAF3 AMHR2 GJA5 THSD7A MEGF8 NFATC1 HCN4 MYOD1 NACA LAMA1 PTCH1 ENPEP SVEP1 HEXIM1 NOTCH4 CRB2 TIPARP CFHR4	9.48e-06	1442	81	18	GO:0072359
GeneOntologyBiologicalProcess	epithelium development	GJA5 MEGF8 NFATC1 LCE3D LAMA1 LRP4 SCRIB CSMD1 PTCH1 EN1 PALB2 NOTCH4 ADAMTSL2 CRB2 STRCP1 LCE3E CFHR4	4.62e-05	1469	81	17	GO:0060429
GeneOntologyBiologicalProcess	animal organ morphogenesis	GJA5 MEGF8 NFATC1 NACA LAMA1 LAMA2 LRP4 SCRIB CSMD1 PTCH1 PALB2 CRB2 TIPARP STRCP1 CFHR4	1.10e-04	1269	81	15	GO:0009887
GeneOntologyBiologicalProcess	extracellular matrix organization	COL9A3 COL12A1 FMOD LAMA1 LAMA2 ADAMTS13 LTBP4 ADAMTSL2	1.16e-04	377	81	8	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL9A3 COL12A1 FMOD LAMA1 LAMA2 ADAMTS13 LTBP4 ADAMTSL2	1.18e-04	378	81	8	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL9A3 COL12A1 FMOD LAMA1 LAMA2 ADAMTS13 LTBP4 ADAMTSL2	1.21e-04	379	81	8	GO:0045229
GeneOntologyBiologicalProcess	regulation of muscle cell differentiation	NFATC1 MYOD1 NACA LAMA1 LAMA2 NOTCH4	1.33e-04	199	81	6	GO:0051147
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	MAP1A MEGF8 LAMA1 LAMA2 LRP4 SCRIB COL25A1 ROBO3 PTCH1 AGRN STRCP1	1.59e-04	748	81	11	GO:0048667
GeneOntologyCellularComponent	extracellular matrix	COL9A3 COL12A1 FCGBP FMOD LAMA1 LAMA2 MUC5B ADAMTS13 COL25A1 EDIL3 LTBP4 SSPOP MUC5AC AGRN SVEP1 ADAMTSL2	3.08e-09	656	80	16	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL9A3 COL12A1 FCGBP FMOD LAMA1 LAMA2 MUC5B ADAMTS13 COL25A1 EDIL3 LTBP4 SSPOP MUC5AC AGRN SVEP1 ADAMTSL2	3.21e-09	658	80	16	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL9A3 COL12A1 FMOD LAMA1 LAMA2 COL25A1 EDIL3 LTBP4 SSPOP AGRN	3.38e-05	530	80	10	GO:0062023
GeneOntologyCellularComponent	FACIT collagen trimer	COL9A3 COL12A1	2.15e-04	6	80	2	GO:0005593
GeneOntologyCellularComponent	Golgi lumen	FMOD MUC5B MUC5AC AGRN	8.16e-04	109	80	4	GO:0005796
MousePheno	increased embryo size	IGF2R PTCH1 CRB2	5.29e-06	8	65	3	MP:0001699
MousePheno	abnormal tricuspid valve development	IGF2R NFATC1	2.13e-05	2	65	2	MP:0031552
MousePheno	abnormal sternum morphology	IGF2R MEGF8 SPNS3 PTCH1 EN1 LTBP4 SSPOP TIPARP	2.26e-05	255	65	8	MP:0000157
MousePheno	abnormal pectoral girdle bone morphology	IGF2R MEGF8 SPNS3 PTCH1 EN1 LTBP4 SSPOP TIPARP	7.32e-05	301	65	8	MP:0004508
MousePheno	perinatal lethality	GJA5 COL12A1 IGF2R LAMA2 LRP4 SCRIB COL25A1 ROBO3 EN1 UNC79 AGRN SH2B1 HEXIM1 ADAMTSL2 BAHCC1	1.65e-04	1130	65	15	MP:0002081
MousePheno	abnormal atrioventricular valve development	IGF2R NFATC1	2.11e-04	5	65	2	MP:0031550
MousePheno	abnormal tricuspid valve morphology	IGF2R MEGF8 NFATC1	2.31e-04	26	65	3	MP:0002624
MousePheno	abnormal thoracic cage morphology	IGF2R MEGF8 SPNS3 CSMD1 PTCH1 EN1 LTBP4 SSPOP TIPARP	2.73e-04	463	65	9	MP:0004624
MousePheno	abnormal synovial joint morphology	FMOD PTCH1 EN1 EDIL3 TIPARP	2.73e-04	124	65	5	MP:0030804
MousePheno	abnormal atrioventricular valve morphology	GJA5 IGF2R MEGF8 NFATC1	2.93e-04	69	65	4	MP:0002745
MousePheno	abnormal heart development	GJA5 IGF2R MEGF8 NFATC1 PTCH1 HEXIM1 CRB2 TEDC1	3.13e-04	372	65	8	MP:0000267
MousePheno	ectopic digits	LRP4 EN1	3.16e-04	6	65	2	MP:0000568
MousePheno	failure of neuromuscular synapse presynaptic differentiation	LRP4 AGRN	3.16e-04	6	65	2	MP:0001054
MousePheno	polydactyly	IGF2R MEGF8 LRP4 PTCH1 EN1	3.28e-04	129	65	5	MP:0000562
Domain	EGF	FCGBP MEGF8 LAMA1 LAMA2 LRP4 VWCE EDIL3 LTBP4 AGRN SVEP1 NOTCH4 CRB2	2.48e-10	235	78	12	SM00181
Domain	EGF-like_dom	FCGBP MEGF8 LAMA1 LAMA2 LRP4 VWCE EDIL3 LTBP4 AGRN SVEP1 NOTCH4 CRB2	4.82e-10	249	78	12	IPR000742
Domain	EGF_1	MEGF8 LAMA1 LAMA2 LRP4 VWCE EDIL3 LTBP4 SSPOP AGRN SVEP1 NOTCH4 CRB2	6.33e-10	255	78	12	PS00022
Domain	EGF_2	MEGF8 LAMA1 LAMA2 LRP4 VWCE EDIL3 LTBP4 SSPOP AGRN SVEP1 NOTCH4 CRB2	9.82e-10	265	78	12	PS01186
Domain	EGF_CA	MEGF8 LRP4 VWCE EDIL3 LTBP4 AGRN SVEP1 NOTCH4 CRB2	2.01e-09	122	78	9	SM00179
Domain	EGF-like_Ca-bd_dom	MEGF8 LRP4 VWCE EDIL3 LTBP4 AGRN SVEP1 NOTCH4 CRB2	2.32e-09	124	78	9	IPR001881
Domain	EGF_Ca-bd_CS	MEGF8 LRP4 VWCE EDIL3 LTBP4 SVEP1 NOTCH4 CRB2	6.87e-09	97	78	8	IPR018097
Domain	EGF_CA	MEGF8 LRP4 VWCE EDIL3 LTBP4 SVEP1 NOTCH4 CRB2	8.08e-09	99	78	8	PS01187
Domain	ASX_HYDROXYL	MEGF8 LRP4 VWCE EDIL3 LTBP4 SVEP1 NOTCH4 CRB2	8.75e-09	100	78	8	PS00010
Domain	EGF-like_CS	MEGF8 LAMA1 LAMA2 LRP4 VWCE EDIL3 LTBP4 AGRN SVEP1 NOTCH4 CRB2	1.09e-08	261	78	11	IPR013032
Domain	VWC_out	FCGBP MUC5B VWCE SSPOP MUC5AC	1.24e-08	19	78	5	SM00215
Domain	EGF-type_Asp/Asn_hydroxyl_site	MEGF8 LRP4 VWCE EDIL3 LTBP4 SVEP1 NOTCH4 CRB2	1.39e-08	106	78	8	IPR000152
Domain	EGF_3	MEGF8 LRP4 VWCE EDIL3 LTBP4 SSPOP AGRN SVEP1 NOTCH4 CRB2	4.89e-08	235	78	10	PS50026
Domain	TIL	FCGBP MUC5B SSPOP MUC5AC	1.36e-07	12	78	4	PF01826
Domain	C8	FCGBP MUC5B SSPOP MUC5AC	1.36e-07	12	78	4	PF08742
Domain	Unchr_dom_Cys-rich	FCGBP MUC5B SSPOP MUC5AC	1.96e-07	13	78	4	IPR014853
Domain	C8	FCGBP MUC5B SSPOP MUC5AC	1.96e-07	13	78	4	SM00832
Domain	TIL_dom	FCGBP MUC5B SSPOP MUC5AC	2.73e-07	14	78	4	IPR002919
Domain	VWD	FCGBP MUC5B SSPOP MUC5AC	4.93e-07	16	78	4	SM00216
Domain	VWF_type-D	FCGBP MUC5B SSPOP MUC5AC	4.93e-07	16	78	4	IPR001846
Domain	VWFD	FCGBP MUC5B SSPOP MUC5AC	4.93e-07	16	78	4	PS51233
Domain	VWD	FCGBP MUC5B SSPOP MUC5AC	4.93e-07	16	78	4	PF00094
Domain	VWC	FCGBP MUC5B VWCE SSPOP MUC5AC	5.03e-07	38	78	5	SM00214
Domain	VWF_dom	FCGBP MUC5B VWCE SSPOP MUC5AC	8.41e-07	42	78	5	IPR001007
Domain	EGF_CA	MEGF8 LRP4 VWCE LTBP4 SVEP1 NOTCH4	1.57e-06	86	78	6	PF07645
Domain	-	COL12A1 LAMA1 LAMA2 AGRN SVEP1 CRB2	2.82e-06	95	78	6	2.60.120.200
Domain	ConA-like_dom	TRIM43B COL12A1 LAMA1 LAMA2 TRIM43 AGRN SVEP1 CRB2	3.64e-06	219	78	8	IPR013320
Domain	Growth_fac_rcpt_	MEGF8 LAMA1 LRP4 VWCE LTBP4 SVEP1 NOTCH4	3.98e-06	156	78	7	IPR009030
Domain	Laminin_G	COL12A1 LAMA1 LAMA2 AGRN CRB2	4.30e-06	58	78	5	IPR001791
Domain	hEGF	EDIL3 SVEP1 NOTCH4 CRB2	5.34e-06	28	78	4	PF12661
Domain	EGF_LAM_2	MEGF8 LAMA1 LAMA2 AGRN	7.10e-06	30	78	4	PS50027
Domain	EGF_LAM_1	MEGF8 LAMA1 LAMA2 AGRN	7.10e-06	30	78	4	PS01248
Domain	Laminin_G_1	LAMA1 LAMA2 AGRN	1.13e-05	11	78	3	PF00054
Domain	Laminin_EGF	MEGF8 LAMA1 LAMA2 AGRN	1.34e-05	35	78	4	PF00053
Domain	EGF_Lam	MEGF8 LAMA1 LAMA2 AGRN	1.34e-05	35	78	4	SM00180
Domain	EGF	LRP4 EDIL3 AGRN SVEP1 NOTCH4 CRB2	1.44e-05	126	78	6	PF00008
Domain	VWFC_1	MUC5B VWCE SSPOP MUC5AC	1.50e-05	36	78	4	PS01208
Domain	VWFC_2	MUC5B VWCE SSPOP MUC5AC	1.87e-05	38	78	4	PS50184
Domain	LAM_G_DOMAIN	LAMA1 LAMA2 AGRN CRB2	1.87e-05	38	78	4	PS50025
Domain	Laminin_EGF	MEGF8 LAMA1 LAMA2 AGRN	1.87e-05	38	78	4	IPR002049
Domain	LamG	LAMA1 LAMA2 AGRN CRB2	3.37e-05	44	78	4	SM00282
Domain	CTCK_1	MUC5B SSPOP MUC5AC	5.47e-05	18	78	3	PS01185
Domain	TSP_1	THSD7A ADAMTS13 SSPOP ADAMTSL2	1.39e-04	63	78	4	PF00090
Domain	Cys_knot_C	MUC5B SSPOP MUC5AC	1.51e-04	25	78	3	IPR006207
Domain	CTCK_2	MUC5B SSPOP MUC5AC	1.51e-04	25	78	3	PS01225
Domain	TSP1	THSD7A ADAMTS13 SSPOP ADAMTSL2	1.57e-04	65	78	4	SM00209
Domain	TSP1_rpt	THSD7A ADAMTS13 SSPOP ADAMTSL2	1.57e-04	65	78	4	IPR000884
Domain	TSP1	THSD7A ADAMTS13 SSPOP ADAMTSL2	1.57e-04	65	78	4	PS50092
Domain	Laminin_aI	LAMA1 LAMA2	1.71e-04	5	78	2	IPR009254
Domain	Laminin_I	LAMA1 LAMA2	1.71e-04	5	78	2	PF06008
Domain	Laminin_II	LAMA1 LAMA2	1.71e-04	5	78	2	PF06009
Domain	Laminin_domII	LAMA1 LAMA2	1.71e-04	5	78	2	IPR010307
Domain	VWC	MUC5B VWCE MUC5AC	2.13e-04	28	78	3	PF00093
Domain	WxxW_domain	MUC5B MUC5AC	2.55e-04	6	78	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	2.55e-04	6	78	2	PF13330
Domain	LAMININ_IVA	LAMA1 LAMA2	4.74e-04	8	78	2	PS51115
Domain	Laminin_B	LAMA1 LAMA2	4.74e-04	8	78	2	PF00052
Domain	LamB	LAMA1 LAMA2	4.74e-04	8	78	2	SM00281
Domain	Laminin_IV	LAMA1 LAMA2	4.74e-04	8	78	2	IPR000034
Domain	Laminin_G_2	LAMA1 LAMA2 CRB2	6.19e-04	40	78	3	PF02210
Domain	Galactose-bd-like	LAMA1 LAMA2 EDIL3 SSPOP	6.46e-04	94	78	4	IPR008979
Domain	Fol_N	FCGBP AGRN	9.24e-04	11	78	2	IPR003645
Domain	FOLN	FCGBP AGRN	9.24e-04	11	78	2	SM00274
Domain	Sushi	CSMD1 SVEP1 CFHR4	1.34e-03	52	78	3	PF00084
Domain	CUB	MEGF8 ADAMTS13 CSMD1	1.41e-03	53	78	3	PS01180
Domain	CCP	CSMD1 SVEP1 CFHR4	1.49e-03	54	78	3	SM00032
Domain	SUSHI	CSMD1 SVEP1 CFHR4	1.66e-03	56	78	3	PS50923
Domain	Sushi_SCR_CCP_dom	CSMD1 SVEP1 CFHR4	1.74e-03	57	78	3	IPR000436
Domain	CUB_dom	MEGF8 ADAMTS13 CSMD1	1.74e-03	57	78	3	IPR000859
Domain	Glyco_hormone_CN	MUC5B MUC5AC	1.75e-03	15	78	2	IPR006208
Domain	Cys_knot	MUC5B MUC5AC	1.75e-03	15	78	2	PF00007
Domain	Laminin_N	LAMA1 LAMA2	1.99e-03	16	78	2	IPR008211
Domain	LAMININ_NTER	LAMA1 LAMA2	1.99e-03	16	78	2	PS51117
Domain	Laminin_N	LAMA1 LAMA2	1.99e-03	16	78	2	PF00055
Domain	LamNT	LAMA1 LAMA2	1.99e-03	16	78	2	SM00136
Domain	LCE	LCE3D LCE3E	2.25e-03	17	78	2	PF14672
Domain	LCE	LCE3D LCE3E	2.25e-03	17	78	2	IPR028205
Domain	FA58C	EDIL3 SSPOP	3.43e-03	21	78	2	SM00231
Domain	FA58C_3	EDIL3 SSPOP	3.43e-03	21	78	2	PS50022
Domain	FA58C_1	EDIL3 SSPOP	3.43e-03	21	78	2	PS01285
Domain	FA58C_2	EDIL3 SSPOP	3.43e-03	21	78	2	PS01286
Domain	-	LAMA2 EDIL3 SSPOP	3.53e-03	73	78	3	2.60.120.260
Domain	CT	MUC5B MUC5AC	3.77e-03	22	78	2	SM00041
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	FMOD THSD7A MUC5B ADAMTS13 SSPOP MUC5AC AGRN NOTCH4 ADAMTSL2	6.16e-09	143	58	9	M27275
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD7A MUC5B ADAMTS13 SSPOP MUC5AC NOTCH4 ADAMTSL2	1.10e-08	68	58	7	M27303
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL9A3 FMOD LAMA1 LAMA2 LRP4 AGRN	6.51e-07	76	58	6	M27219
Pathway	REACTOME_DISEASES_OF_METABOLISM	FMOD THSD7A MUC5B ADAMTS13 SSPOP MUC5AC AGRN NOTCH4 ADAMTSL2	7.50e-07	250	58	9	M27554
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL9A3 COL12A1 FMOD LAMA1 LAMA2 LRP4 COL25A1 LTBP4 AGRN	3.39e-06	300	58	9	M610
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A MUC5B ADAMTS13 SSPOP MUC5AC ADAMTSL2	5.43e-06	109	58	6	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A MUC5B ADAMTS13 SSPOP MUC5AC ADAMTSL2	6.04e-06	111	58	6	M27416
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD7A ADAMTS13 SSPOP ADAMTSL2	1.91e-05	39	58	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD7A ADAMTS13 SSPOP ADAMTSL2	1.91e-05	39	58	4	MM15165
Pathway	BIOCARTA_AGR_PATHWAY	LAMA1 LAMA2 AGRN	2.74e-04	31	58	3	MM1343
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL9A3 COL12A1 COL25A1	6.31e-04	41	58	3	MM15538
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL9A3 COL12A1 COL25A1	7.77e-04	44	58	3	M27812
Pathway	PID_INTEGRIN4_PATHWAY	LAMA1 LAMA2	8.93e-04	11	58	2	M158
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	IGF2R MEGF8 NFATC1 TMC6 NSD1 LRP4 C15orf39 IRF5 WRAP53 PTCH1 FEM1A LTBP4 AGRN WNK2 BAHCC1	4.21e-08	1105	82	15	35748872
Pubmed	Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain.	LAMA1 LAMA2 AGRN	5.04e-08	4	82	3	32072250
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	COL12A1 FMOD LAMA1 LAMA2 LTBP4 AGRN SVEP1 CFHR4	1.35e-07	248	82	8	24006456
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL9A3 COL12A1 LAMA1 LAMA2 COL25A1 LTBP4 AGRN	1.46e-07	167	82	7	22159717
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	MCTP1 THSD7A LAMA2 SSPOP MUC5AC	7.42e-07	71	82	5	33541421
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL12A1 FMOD LAMA2 EDIL3 LTBP4 AGRN	1.33e-06	146	82	6	27068509
Pubmed	Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.	IGF2R CSMD1 EN1 BICD1	2.22e-06	39	82	4	19010793
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	LAMA1 LAMA2 AGRN	2.74e-06	12	82	3	16750824
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	MYOD1 LAMA1 LAMA2	3.55e-06	13	82	3	9833687
Pubmed	Differential effects of spinal motor neuron-derived and skeletal muscle-derived Rspo2 on acetylcholine receptor clustering at the neuromuscular junction.	MYOD1 LRP4 AGRN	3.55e-06	13	82	3	30206360
Pubmed	Epaxial-adaxial-hypaxial regionalisation of the vertebrate somite: evidence for a somitic organiser and a mirror-image duplication.	GJA5 MYOD1 EN1	3.55e-06	13	82	3	11455436
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL12A1 LAMA1 LAMA2 LTBP4 SSPOP AGRN	3.80e-06	175	82	6	28071719
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	5.49e-06	2	82	2	7513696
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	5.49e-06	2	82	2	37146737
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	5.49e-06	2	82	2	14988081
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	5.49e-06	2	82	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	5.49e-06	2	82	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	5.49e-06	2	82	2	24317696
Pubmed	Laminin 2 attachment selects myofibroblasts from fetal mouse lung.	LAMA1 LAMA2	5.49e-06	2	82	2	9728058
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	5.49e-06	2	82	2	22391959
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	5.49e-06	2	82	2	35776514
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	5.49e-06	2	82	2	24327612
Pubmed	The role of connexin40 in developing atrial conduction.	GJA5 HCN4	5.49e-06	2	82	2	24486905
Pubmed	Aberrant interaction between mutated ADAMTSL2 and LTBP4 is associated with adolescent idiopathic scoliosis.	LTBP4 ADAMTSL2	5.49e-06	2	82	2	34958866
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	5.49e-06	2	82	2	28607090
Pubmed	Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses.	LRP4 AGRN	5.49e-06	2	82	2	22854782
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	5.49e-06	2	82	2	31030254
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	5.49e-06	2	82	2	23527003
Pubmed	Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin.	LAMA2 AGRN	5.49e-06	2	82	2	16103356
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	5.49e-06	2	82	2	16540890
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	5.49e-06	2	82	2	27845589
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	5.49e-06	2	82	2	27435107
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	5.49e-06	2	82	2	26871672
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	5.49e-06	2	82	2	11587997
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	5.49e-06	2	82	2	34656442
Pubmed	Transgenic overexpression of laminin alpha1 chain in laminin alpha2 chain-deficient mice rescues the disease throughout the lifespan.	LAMA1 LAMA2	5.49e-06	2	82	2	20544910
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	5.49e-06	2	82	2	34058148
Pubmed	Conserved neuron promoting activity in Drosophila and vertebrate laminin alpha1.	LAMA1 LAMA2	5.49e-06	2	82	2	8663504
Pubmed	Laminin α1 reduces muscular dystrophy in dy2J mice.	LAMA1 LAMA2	5.49e-06	2	82	2	29544677
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	5.49e-06	2	82	2	14718370
Pubmed	MyoD is a tumor suppressor gene in medulloblastoma.	MYOD1 PTCH1	5.49e-06	2	82	2	24092238
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	5.49e-06	2	82	2	21653907
Pubmed	Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation.	LAMA1 EDIL3	5.49e-06	2	82	2	20048158
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	5.49e-06	2	82	2	36427316
Pubmed	Laminin α1 regulates age-related mesangial cell proliferation and mesangial matrix accumulation through the TGF-β pathway.	LAMA1 EDIL3	5.49e-06	2	82	2	24720953
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	5.49e-06	2	82	2	23272068
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	5.49e-06	2	82	2	27729120
Pubmed	A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition.	LRP4 PTCH1	5.49e-06	2	82	2	20018657
Pubmed	ADAMTS-like 2 (ADAMTSL2) is a secreted glycoprotein that is widely expressed during mouse embryogenesis and is regulated during skeletal myogenesis.	ADAMTS13 ADAMTSL2	5.49e-06	2	82	2	17509843
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	5.49e-06	2	82	2	36111525
Pubmed	Functional role of laminin α1 chain during cerebellum development.	LAMA1 EDIL3	5.49e-06	2	82	2	22274713
Pubmed	Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiency.	LAMA1 LAMA2	5.49e-06	2	82	2	20657839
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	5.49e-06	2	82	2	32348677
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	5.49e-06	2	82	2	24332705
Pubmed	Vitamin B(12) promotes Cx40 and HCN4 gene expression at an early stage of cardiomyocyte differentiation.	GJA5 HCN4	5.49e-06	2	82	2	19151513
Pubmed	Slit-roundabout signaling regulates the development of the cardiac systemic venous return and pericardium.	GJA5 HCN4 ROBO3	5.63e-06	15	82	3	23255421
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	LAMA1 LAMA2 AGRN	6.92e-06	16	82	3	17948866
Pubmed	Laminin α1 is essential for mouse cerebellar development.	LAMA1 LAMA2 EDIL3	8.39e-06	17	82	3	21983115
Pubmed	Region-specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord.	PTCH1 EN1 EDIL3	1.19e-05	19	82	3	17507410
Pubmed	Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap.	SCRIB MUC5AC CRB2	1.19e-05	19	82	3	26235047
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	THSD7A LRP4 SSPOP SH2B1 BAHCC1	1.46e-05	130	82	5	12421765
Pubmed	LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction.	LRP4 EN1 AGRN	1.63e-05	21	82	3	17119023
Pubmed	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	IRF5 COL25A1 NOTCH4	1.63e-05	21	82	3	21408207
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	LAMA1 LAMA2 SSPOP AGRN	1.64e-05	64	82	4	22261194
Pubmed	[Replicative association analysis of genetic markers of cognitive traits with Alzheimer's disease in a Russian population].	CSMD1 NOTCH4	1.64e-05	3	82	2	25845235
Pubmed	High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.	MUC5B MUC5AC	1.64e-05	3	82	2	29286856
Pubmed	SVEP1 plays a crucial role in epidermal differentiation.	EDIL3 SVEP1	1.64e-05	3	82	2	27892606
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	MUC5B MUC5AC	1.64e-05	3	82	2	36675209
Pubmed	MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters.	LRP4 AGRN	1.64e-05	3	82	2	24244707
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5B MUC5AC	1.64e-05	3	82	2	29802623
Pubmed	Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation.	GJA5 HCN4	1.64e-05	3	82	2	25144323
Pubmed	Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK).	LRP4 AGRN	1.64e-05	3	82	2	21969364
Pubmed	Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine.	LAMA1 LAMA2	1.64e-05	3	82	2	7803849
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	MUC5B MUC5AC	1.64e-05	3	82	2	29604272
Pubmed	Expression of laminin chains during myogenic differentiation.	LAMA1 LAMA2	1.64e-05	3	82	2	7510707
Pubmed	Aquaporin 5 expression increases mucin production in lung adenocarcinoma.	MUC5B MUC5AC	1.64e-05	3	82	2	21455588
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B MUC5AC	1.64e-05	3	82	2	20422702
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC5AC	1.64e-05	3	82	2	19718741
Pubmed	Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.	MUC5B MUC5AC	1.64e-05	3	82	2	27776277
Pubmed	Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP.	HCN4 ENPEP	1.64e-05	3	82	2	25888893
Pubmed	Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.	MUC5B MUC5AC	1.64e-05	3	82	2	34158522
Pubmed	Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy.	ADAMTS13 CFHR4	1.64e-05	3	82	2	31409673
Pubmed	IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.	MUC5B MUC5AC	1.64e-05	3	82	2	19596978
Pubmed	Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.	LAMA1 LAMA2	1.64e-05	3	82	2	7925941
Pubmed	Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.	LAMA1 LAMA2	1.64e-05	3	82	2	16504180
Pubmed	Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.	MUC5B MUC5AC	1.64e-05	3	82	2	19556605
Pubmed	Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal.	LAMA1 EDIL3	1.64e-05	3	82	2	29540680
Pubmed	Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.	LAMA1 LAMA2	1.64e-05	3	82	2	16709410
Pubmed	Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling.	MYOD1 PTCH1 EN1	2.80e-05	25	82	3	12421714
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	THSD7A ADAMTS13 SSPOP ADAMTSL2	3.07e-05	75	82	4	20637190
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL9A3 COL12A1 LAMA2 COL25A1 LTBP4	3.20e-05	153	82	5	25037231
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC5AC	3.28e-05	4	82	2	25638393
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC5AC	3.28e-05	4	82	2	22269464
Pubmed	Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.	MUC5B MUC5AC	3.28e-05	4	82	2	18258655
Pubmed	Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency.	MYOD1 LAMA1	3.28e-05	4	82	2	21131290
Pubmed	Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.	LAMA1 LAMA2	3.28e-05	4	82	2	2099832
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC5AC	3.28e-05	4	82	2	23807779
Pubmed	Molecular recognition by LARGE is essential for expression of functional dystroglycan.	LAMA1 LAMA2	3.28e-05	4	82	2	15210115
Pubmed	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	MUC5B MUC5AC	3.28e-05	4	82	2	31582416
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC5AC	3.28e-05	4	82	2	17471237
Cytoband	9q22.3	PTCH1 WNK2	2.06e-04	12	82	2	9q22.3
Cytoband	15q15.3	MAP1A STRCP1	9.21e-04	25	82	2	15q15.3
Cytoband	2q11.1	TRIM43B TRIM43	1.16e-03	28	82	2	2q11.1
Cytoband	7p21.3	THSD7A GLCCI1	1.16e-03	28	82	2	7p21.3
Cytoband	11p15.5	DRD4 MUC5B MUC5AC	1.26e-03	118	82	3	11p15.5
Cytoband	Ensembl 112 genes in cytogenetic band chr15q15	MAP1A PPP1R14D STRCP1	2.37e-03	147	82	3	chr15q15
GeneFamily	Collagens\|Collagen proteoglycans	COL9A3 COL12A1	8.38e-05	5	53	2	575
GeneFamily	Collagens	COL9A3 COL12A1 COL25A1	3.30e-04	46	53	3	490
GeneFamily	Laminin subunits	LAMA1 LAMA2	5.46e-04	12	53	2	626
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CSMD1 SVEP1 CFHR4	6.22e-04	57	53	3	1179
GeneFamily	Late cornified envelope proteins	LCE3D LCE3E	1.25e-03	18	53	2	627
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	1.71e-03	21	53	2	648
Coexpression	NABA_CORE_MATRISOME	COL9A3 COL12A1 FMOD LAMA1 LAMA2 COL25A1 VWCE EDIL3 LTBP4 SSPOP AGRN SVEP1	4.88e-11	270	82	12	MM17057
Coexpression	NABA_CORE_MATRISOME	COL9A3 COL12A1 FMOD LAMA1 LAMA2 COL25A1 VWCE EDIL3 LTBP4 SSPOP AGRN SVEP1	6.04e-11	275	82	12	M5884
Coexpression	NABA_MATRISOME	COL9A3 COL12A1 FMOD MEGF8 LAMA1 LAMA2 MUC5B ADAMTS13 COL25A1 VWCE EDIL3 LTBP4 SSPOP MUC5AC AGRN SVEP1 ADAMTSL2	1.18e-08	1008	82	17	MM17056
Coexpression	NABA_MATRISOME	COL9A3 COL12A1 FMOD MEGF8 LAMA1 LAMA2 MUC5B ADAMTS13 COL25A1 VWCE EDIL3 LTBP4 SSPOP MUC5AC AGRN SVEP1 ADAMTSL2	1.54e-08	1026	82	17	M5889
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA1 LAMA2 VWCE EDIL3 LTBP4 SSPOP AGRN SVEP1	1.54e-07	191	82	8	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA1 LAMA2 VWCE EDIL3 LTBP4 SSPOP AGRN SVEP1	1.88e-07	196	82	8	M3008
Coexpression	GSE3039_CD4_TCELL_VS_B2_BCELL_UP	RNF144B MCTP1 SP110 AGRN GLCCI1 SH2B1 TEDC1	3.18e-06	200	82	7	M6462
Coexpression	NABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR	FMOD MEGF8 AGRN SVEP1	3.55e-05	59	82	4	M47989
Coexpression	TRAVAGLINI_LUNG_ARTERY_CELL	RNF144B GJA5 THSD7A LTBP4 TIPARP	5.79e-05	131	82	5	M41662
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	GJA5 IGF2R LRP4 COL25A1 LTBP4 ENPEP SMIM41 SVEP1	2.48e-09	191	82	8	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IGF2R LRP4 COL25A1 PTCH1 ENPEP SMIM41 SVEP1 ADAMTSL2	2.80e-09	194	82	8	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	IGF2R LRP4 COL25A1 LTBP4 ENPEP SVEP1 ADAMTSL2	5.80e-08	188	82	7	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	3'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF144B GJA5 MCTP1 THSD7A NFATC1 COL25A1 NOTCH4	6.02e-08	189	82	7	0c612ff5f882f2d8ec744a347780bbbe7cc471bd
ToppCell	3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF144B GJA5 MCTP1 THSD7A NFATC1 COL25A1 NOTCH4	6.02e-08	189	82	7	bc8949bd4f425ed36e2c05e653c94cb1593c5bee
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	6.47e-08	191	82	7	36467322096bc766cd777dae3bfb4e65511e492c
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	6.47e-08	191	82	7	94795daf05061baa3b72a1b01c9e940af86de044
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IGF2R LRP4 COL25A1 ENPEP SMIM41 SVEP1 ADAMTSL2	6.47e-08	191	82	7	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	6.47e-08	191	82	7	c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	6.47e-08	191	82	7	243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LRP4 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	6.47e-08	191	82	7	d4f535b06ad483448ab692e9900c872c78cbed60
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LRP4 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	6.47e-08	191	82	7	b5210de890d338602857b5907135705a507bc2b0
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LRP4 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	6.94e-08	193	82	7	fa45042d30f9cfeed10e23270a78f18551219cfa
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA5 LAMA2 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	6.94e-08	193	82	7	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA5 LAMA2 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	6.94e-08	193	82	7	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LRP4 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	6.94e-08	193	82	7	ab511ea9e09216a965b3ae5a94f8c3c1ae33d944
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 PTCH1 LTBP4 SVEP1 ADAMTSL2	7.45e-08	195	82	7	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 PTCH1 LTBP4 SVEP1 ADAMTSL2	7.71e-08	196	82	7	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IGF2R LRP4 COL25A1 ENPEP SMIM41 SVEP1 ADAMTSL2	7.71e-08	196	82	7	54f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGF2R COL25A1 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	7.71e-08	196	82	7	97e26622d9582b092c18ff5b7e957818f99d9631
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGF2R COL25A1 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	7.71e-08	196	82	7	f429f045ba45e24717963315832150b12a115bfa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 PTCH1 LTBP4 SVEP1 ADAMTSL2	7.71e-08	196	82	7	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 PTCH1 LTBP4 SVEP1 ADAMTSL2	7.99e-08	197	82	7	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	(3)_Chondrocytes-(30)_Chondro\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	COL9A3 COL12A1 FMOD PTCH1 VWCE EDIL3 WNK2	7.99e-08	197	82	7	a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	COL12A1 LAMA2 ADAMTS13 COL25A1 LTBP4 SVEP1 ADAMTSL2	8.27e-08	198	82	7	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL9A3 FCGBP LAMA1 MUC5B ADAMTS13 WNK2	4.79e-07	158	82	6	adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL9A3 COL12A1 MYOD1 VWCE WNK2 ADAMTSL2	4.79e-07	158	82	6	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL9A3 COL12A1 MYOD1 VWCE WNK2 ADAMTSL2	4.79e-07	158	82	6	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	PLEKHH1 FCGBP PLEKHG7 MUC5B MUC5AC WNK2	6.63e-07	167	82	6	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 PTCH1 EDIL3 LTBP4 SVEP1 CFHR4	7.10e-07	169	82	6	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FMOD LAMA2 PTCH1 LTBP4 SVEP1 TIPARP	8.42e-07	174	82	6	9c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FMOD LAMA2 PTCH1 LTBP4 SVEP1 TIPARP	8.42e-07	174	82	6	bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 PTCH1 LTBP4 SVEP1 ADAMTSL2	9.62e-07	178	82	6	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 FMOD MAP1A LAMA2 LTBP4 SVEP1	1.06e-06	181	82	6	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL12A1 LAMA2 LRP4 ADAMTS13 PTCH1 LTBP4	1.06e-06	181	82	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 FMOD MAP1A LAMA2 LTBP4 SVEP1	1.06e-06	181	82	6	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	GJA5 IGF2R COL25A1 ENPEP SMIM41 SVEP1	1.09e-06	182	82	6	ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL9A3 COL12A1 SCRIB CSMD1 EDIL3 AGRN	1.09e-06	182	82	6	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 LAMA1 MUC5B CSMD1 SSPOP UNC79	1.17e-06	184	82	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LRP4 LTBP4 ENPEP SMIM41 SVEP1 ADAMTSL2	1.17e-06	184	82	6	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 LAMA1 MUC5B CSMD1 SSPOP UNC79	1.17e-06	184	82	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 LAMA1 MUC5B CSMD1 SSPOP UNC79	1.17e-06	184	82	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMOD LAMA2 CSMD1 EN1 LTBP4 SVEP1	1.24e-06	186	82	6	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRP4 ADAMTS13 PTCH1 EDIL3 LTBP4 SMIM41	1.24e-06	186	82	6	360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LAMA2 LRP4 LTBP4 SMIM41 SVEP1	1.36e-06	189	82	6	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	facs-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	1.36e-06	189	82	6	bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LAMA2 LRP4 LTBP4 SMIM41 SVEP1	1.36e-06	189	82	6	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA5 MCTP1 THSD7A LTBP4 AGRN NOTCH4	1.36e-06	189	82	6	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 SMIM41 SVEP1 ADAMTSL2	1.36e-06	189	82	6	40cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GJA5 MCTP1 THSD7A CSMD1 LTBP4 NOTCH4	1.36e-06	189	82	6	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	IGF2R LAMA2 LRP4 COL25A1 LTBP4 SVEP1	1.36e-06	189	82	6	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	1.36e-06	189	82	6	e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LAMA2 LRP4 LTBP4 SMIM41 SVEP1	1.41e-06	190	82	6	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	droplet-Lung-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	1.41e-06	190	82	6	0b7200897b2c389632c9b1ee37e272b811555dbc
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.45e-06	191	82	6	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LRP4 LTBP4 ENPEP SMIM41 SVEP1	1.45e-06	191	82	6	a261f0738d974784bbdd60f23092bfbcca464459
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 SMIM41 SVEP1 ADAMTSL2	1.45e-06	191	82	6	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	1.45e-06	191	82	6	8a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LRP4 ENPEP SMIM41 SVEP1 ADAMTSL2	1.45e-06	191	82	6	beb5bb42bd53bce01339da9110d374901548793c
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LRP4 LTBP4 ENPEP SMIM41 SVEP1	1.45e-06	191	82	6	6594398cc8151c73696391a43ac110c10283dab1
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LRP4 ENPEP SMIM41 SVEP1 ADAMTSL2	1.45e-06	191	82	6	6609d85fd2577633dcc067507304a6f9e5865ca3
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA5 MCTP1 THSD7A LTBP4 AGRN NOTCH4	1.45e-06	191	82	6	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	facs-Lung-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 SMIM41 SVEP1 ADAMTSL2	1.45e-06	191	82	6	ba02cbdfda6a94374a6472eb88499059979af472
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	RNF144B GJA5 THSD7A CSMD1 LTBP4 TIPARP	1.45e-06	191	82	6	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA5 LRP4 LTBP4 SMIM41 SVEP1 ADAMTSL2	1.45e-06	191	82	6	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GJA5 MCTP1 THSD7A CSMD1 LTBP4 NOTCH4	1.45e-06	191	82	6	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 SMIM41 SVEP1 ADAMTSL2	1.45e-06	191	82	6	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	droplet-Lung-21m-Mesenchymal\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LRP4 LTBP4 ENPEP SMIM41 SVEP1	1.45e-06	191	82	6	10a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.49e-06	192	82	6	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.49e-06	192	82	6	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	RNF144B GJA5 MCTP1 THSD7A CSMD1 LTBP4	1.49e-06	192	82	6	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	(3)_Chondrocytes\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	COL9A3 COL12A1 FMOD NFATC1 PTCH1 EDIL3	1.49e-06	192	82	6	5d2b4830d025d3dbdf5623ce1c28d1036e1984a8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.54e-06	193	82	6	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 FMOD LAMA2 LTBP4 SVEP1 ADAMTSL2	1.54e-06	193	82	6	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LRP4 ENPEP SMIM41 SVEP1 ADAMTSL2	1.54e-06	193	82	6	027e098ad018e782287f84eee0f77551018f2196
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LRP4 ENPEP SMIM41 SVEP1 ADAMTSL2	1.54e-06	193	82	6	c5463a87f20b3a7f7ffda677b2f5a0e9e49d6685
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA5 LRP4 ENPEP SMIM41 SVEP1 ADAMTSL2	1.54e-06	193	82	6	abdfb8b1dbdcb424042e21017a9e829fced4457e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 FMOD LAMA2 LTBP4 SVEP1 ADAMTSL2	1.54e-06	193	82	6	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GJA5 FMOD THSD7A EDIL3 ENPEP SVEP1	1.59e-06	194	82	6	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 FMOD LAMA2 LTBP4 SVEP1 ADAMTSL2	1.59e-06	194	82	6	29f83cdd63314fff41258937d70b881a5503bfcc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 PTCH1 LTBP4 SVEP1 ADAMTSL2	1.59e-06	194	82	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 FMOD LAMA2 LTBP4 SVEP1 ADAMTSL2	1.59e-06	194	82	6	d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GJA5 THSD7A LAMA2 EDIL3 ENPEP SVEP1	1.59e-06	194	82	6	a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 FMOD LAMA2 PTCH1 EDIL3 SVEP1	1.63e-06	195	82	6	18b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.63e-06	195	82	6	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.63e-06	195	82	6	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FMOD LAMA2 LTBP4 ENPEP SVEP1 ADAMTSL2	1.63e-06	195	82	6	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FMOD LAMA2 LTBP4 ENPEP SVEP1 ADAMTSL2	1.63e-06	195	82	6	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.63e-06	195	82	6	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.63e-06	195	82	6	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 COL25A1 LTBP4 SVEP1 ADAMTSL2	1.63e-06	195	82	6	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FMOD LAMA2 LTBP4 ENPEP SVEP1 ADAMTSL2	1.68e-06	196	82	6	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 PTCH1 EDIL3 LTBP4 SMIM41 SVEP1	1.68e-06	196	82	6	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGF2R COL25A1 ENPEP SMIM41 SVEP1 ADAMTSL2	1.68e-06	196	82	6	617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FMOD LAMA2 LTBP4 ENPEP SVEP1 ADAMTSL2	1.68e-06	196	82	6	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGF2R COL25A1 ENPEP SMIM41 SVEP1 ADAMTSL2	1.68e-06	196	82	6	db64ab27374f82553ee577aec056141170f3656f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FMOD LAMA2 LTBP4 ENPEP SVEP1 ADAMTSL2	1.68e-06	196	82	6	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NFATC1 LAMA2 LTBP4 SVEP1 ADAMTSL2 BICD1	1.73e-06	197	82	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	Influenza-Influenza_Severe-Myeloid-pDC\|Influenza_Severe / Disease, condition lineage and cell class	DRD4 MAP1A SPNS3 ROBO3 NOTCH4 BICD1	1.73e-06	197	82	6	e8e6f71e6dc8a695e4321a18543c1df63dd62f3e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMA2 PTCH1 LTBP4 SVEP1 ADAMTSL2	1.73e-06	197	82	6	ae0435f4b4a9cdedb1c201fc56921048390097bf
Disease	interstitial lung disease	MUC5B CSMD1 MUC5AC NOTCH4	3.37e-05	67	80	4	EFO_0004244
Disease	citrate measurement	RNF144B IGF2R NFATC1 WNK2	6.45e-05	79	80	4	EFO_0010114
Disease	complement factor H-related protein 3 measurement	FAM47A COL12A1 NFATC1 MAGEC2 CFHR4	9.87e-05	169	80	5	EFO_0600056
Disease	Gilles de la Tourette syndrome (is_implicated_in)	DRD4 HCN4	1.08e-04	6	80	2	DOID:11119 (is_implicated_in)
Disease	heart rate variability measurement, response to antipsychotic drug	COL12A1 PRSS56 CSMD1	2.68e-04	46	80	3	EFO_0008003, GO_0097332
Disease	glucagon-like peptide-1 measurement	COL12A1 CSMD1	3.22e-04	10	80	2	EFO_0008465
Disease	periodontitis	FAM47A IGF2R PLEKHG7 LAMA2 CSMD1	3.58e-04	223	80	5	EFO_0000649
Disease	pulmonary fibrosis	MUC5B MUC5AC	3.93e-04	11	80	2	EFO_0009448
Disease	rotator cuff tear	THSD7A GLCCI1	4.71e-04	12	80	2	EFO_1001250
Disease	tyrosine-protein kinase receptor Tie-1, soluble measurement	ADAMTS13 ADAMTSL2	5.55e-04	13	80	2	EFO_0008312
Disease	triacylglycerol 52:1 measurement	NFATC1 CSMD1	6.47e-04	14	80	2	EFO_0010413
Disease	CD209 antigen measurement	ADAMTS13 ADAMTSL2	6.47e-04	14	80	2	EFO_0008077
Disease	cholangiocarcinoma (is_marker_for)	PRSS56 MUC5B MUC5AC	7.10e-04	64	80	3	DOID:4947 (is_marker_for)
Disease	glycerate measurement	MCTP1 AGRN	7.45e-04	15	80	2	EFO_0021029
Disease	Rhabdomyosarcoma	MYOD1 PTCH1	7.45e-04	15	80	2	C0035412
Disease	Myopia	PRSS56 LAMA2	7.45e-04	15	80	2	C0027092
Disease	Myasthenic Syndromes, Congenital, Slow Channel	LRP4 AGRN	8.50e-04	16	80	2	C0751885
Disease	Dyskeratosis Congenita	NAF1 WRAP53	8.50e-04	16	80	2	C0265965
Disease	Congenital Myasthenic Syndromes, Postsynaptic	LRP4 AGRN	9.61e-04	17	80	2	C0751883
Disease	neuroimaging measurement, brain volume measurement	PTCH1 SH2B1 WNK2 CRB2 BICD1	1.10e-03	286	80	5	EFO_0004346, EFO_0006930
Disease	Congenital hernia of foramen of Morgagni	IGF2R MYOD1	1.20e-03	19	80	2	C0265699
Disease	Congenital Myasthenic Syndromes, Presynaptic	LRP4 AGRN	1.20e-03	19	80	2	C0751884
Disease	Congenital hernia of foramen of Bochdalek	IGF2R MYOD1	1.20e-03	19	80	2	C0265700
Disease	renovascular hypertension (biomarker_via_orthology)	GJA5 LAMA2	1.20e-03	19	80	2	DOID:1591 (biomarker_via_orthology)
Disease	chemerin measurement	PTCH1 EDIL3	1.20e-03	19	80	2	EFO_0004573
Disease	Multiple Epiphyseal Dysplasia	COL9A3 ADAMTSL2	1.34e-03	20	80	2	C0026760
Disease	triacylglycerol 46:1 measurement	NFATC1 CSMD1	1.34e-03	20	80	2	EFO_0010401
Disease	Congenital diaphragmatic hernia	IGF2R MYOD1	1.47e-03	21	80	2	C0235833
Disease	Myasthenic Syndromes, Congenital	LRP4 AGRN	1.93e-03	24	80	2	C0751882
Disease	triacylglycerol 56:5 measurement	EDIL3 MAGEC2	2.26e-03	26	80	2	EFO_0010432
Disease	neuroimaging measurement	DXO DNAAF3 LAMA2 ROBO3 PTCH1 GLCCI1 WNK2 BICD1 BAHCC1	2.41e-03	1069	80	9	EFO_0004346
Disease	nicotine withdrawal measurement	COL9A3 CSMD1	2.44e-03	27	80	2	EFO_0009362

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSSTAPAQPPTANPC	BAHCC1	1386	Q9P281
PEGATDLQCPSICPP	COL9A3	166	Q14050
PDCQQPAASVPPQCS	BICD1	921	Q96G01
PTCIDPAHNTCPDPG	CSMD1	3206	Q96PZ7
APEPSCRCPGTAQDQ	C2orf27A	46	P0DPF5
PCDPCQGALPDPSRS	AGRN	316	O00468
CVSPFCPPESQDGSP	GLCCI1	366	Q86VQ1
QPAVALETCNPQPCP	ADAMTS13	791	Q76LX8
PQESHPFPESCPRGC	AMHR2	511	Q16671
TEQCPDPLPLPAGNC	MUC5B	241	Q9HC84
NTTTCPQSLPVCPPG	MUC5B	5486	Q9HC84
PQSLPVCPPGQESIC	MUC5B	5491	Q9HC84
SCTEHDPCGPNPLEP	NSD1	2201	Q96L73
DCVVQPPSPPDDFSC	TIPARP	11	Q7Z3E1
AAVGPPNPRADPECC	INTS13	106	Q9NVM9
CQTVCPVASSDPGQP	RNF144B	126	Q7Z419
CPGSPSPQPDSTDND	CD6	646	P30203
GSPSPPDPRDCPQEC	FMOD	66	Q06828
PDTANQEPTPKSPCG	MAP1A	1161	P78559
DCAANGPTETSPNPP	MAP1A	2356	P78559
QPNLCCSSPEPLEPG	MCTP1	96	Q6DN14
PPQGPSQSPLSSCCS	MAGEC2	91	Q9UBF1
QPCLPPATCEEVPDG	CRB2	851	Q5IJ48
PVSVQSPCGQPTPCS	KRTAP2-2	101	Q9BYT5
PPPLQTQACPESSCL	HEXIM1	71	O94992
DPTQSPDAAPQCPAG	MYOD1	296	P15172
AREAPSECNCPAGPP	COL25A1	111	Q9BXS0
LPPATQEPTCLQPCS	NFATC1	851	O95644
GPGSCPVPQECVPQD	MEGF8	1411	Q7Z7M0
PCPTEPPDDSCQDQP	ADAMTSL2	906	Q86TH1
PCACPLNIPSNNFSP	LAMA2	806	P24043
DQCQDPVPEPPRNCS	MUC5AC	246	P98088
SPSGPPAQDQDICPA	ENPEP	66	Q07075
CSNGPAPTDSQPPED	IRF5	121	Q13568
CAPDANCGPPDGSQP	EN1	171	Q05925
DCTDPQAPSTQPPTC	DXO	236	O77932
AAPSLPQDPCGPDCA	DRD4	281	P21917
PPQPASASCEQPSVD	HCN4	171	Q9Y3Q4
GQPTCDCDSVPPGTP	PALB2	796	Q86YC2
EPTSAGPCTPNPCHN	EDIL3	71	O43854
TPHCEPCQLPSESPG	DNAAF3	501	Q8N9W5
PNSCTCTQDSVGPPG	COL12A1	2736	Q99715
KPCPSPCTPEQQESF	FCGBP	2246	Q9Y6R7
SKPCPSPCTPEQQES	FCGBP	3446	Q9Y6R7
VSKPCPSPCTPEQQE	FCGBP	4646	Q9Y6R7
CTPPPDFNQCLENGP	GJA5	261	P36382
QPQGAPCCSSSPEEP	FEM1A	266	Q9BSK4
LPTCYNSSENCGPPP	CFHR4	201	Q92496
QEPPPCGPGRCDNTA	LTBP4	716	Q8N2S1
SPCGEPCLQPPETQV	FAM47A	461	Q5JRC9
PVQCLPPASSGCAPS	LCE3D	26	Q9BYE3
PVQCLPPASSGCAPS	LCE3E	26	Q5T5B0
LSPGPSPQSPSCCFQ	C20orf173	36	Q96LM9
CLPQEPQEPPAGTAC	PRSS56	211	P0CW18
AACPCPQSSPPEQKE	PRR14L	1986	Q5THK1
PASCTSPSPDGENPC	PPP1R14D	6	Q9NXH3
PVSVSPCQPDSGACQ	IGF2R	666	P11717
IQECLSPGPCPATSP	SH2B1	371	Q9NRF2
AQSPANCPACREPSP	TRIM43	46	Q96BQ3
TQPLAPDCCPSDQDP	WRAP53	6	Q9BUR4
LAASSPPPCSQPSQC	TSEN54	226	Q7Z6J9
AGQLSCTAQPCPPPT	SSPOP	4146	A2VEC9
PDADRSCNPPCSQPH	THSD7A	1511	Q9UPZ6
CNPVGSASDEPCTGP	LAMA1	456	P25391
CLNPADPDCPATAPN	PTCH1	296	Q13635
SSCCNQSASPPEPPE	SMIM41	16	A0A2R8YCJ5
CPCQPDSGSPLPAEE	SCRIB	496	Q14160
QPSCSPCAPRVSEPG	SP110	146	Q9HB58
SPPVCEPVKCSSPEN	SVEP1	1896	Q4LDE5
CPDGSPGCAPPEDNC	NOTCH4	651	Q99466
ACQPLPASQPCSEPV	C15orf39	416	Q6ZRI6
PPCFQEPCSNPDSLI	SPNS3	296	Q6ZMD2
QEPRGSCCPSNPDPD	ROBO3	976	Q96MS0
VCQCEALASPGPPAP	TEDC1	141	Q86SX3
PSGPCQTPPQTDCCT	VWCE	481	Q96DN2
APVNCSSCPGPPTAS	VWCE	776	Q96DN2
NEFPFGCPPTVCQDP	TRAF1	16	Q13077
CTTTVNPPTNPPGAC	PLEKHH1	1326	Q9ULM0
SFCPEVPPQDCGASP	PLEKHG7	6	Q6ZR37
PTQPPCTRDGPSDCV	STRCP1	156	A6NGW2
AQSPANCPACREPSP	TRIM43B	46	A6NCK2
NQPCGSPLDGSQCTP	TMC6	316	Q7Z403
ADAAPSPAQCVCSPP	WNK2	641	Q9Y3S1
SPAQCVCSPPVSEGP	WNK2	646	Q9Y3S1
GCSNCTQTSPPYPEP	WWC3	821	Q9ULE0
QCPSCNGPIFPPTNL	ZFPL1	96	O95159
NAVCPNASSPCLPIP	UNC79	2426	Q9P2D8
NCPSAVPAPPCNLEE	LRP4	181	O75096
ENCPVAPSPQNTCAP	NACA	706	E9PAV3
PQPQPPAESPACGDC	NAF1	81	Q96HR8