Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesschondrocyte proliferation

GRN CCN2 CCN3

7.81e-0631263GO:0035988
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

KCP BMPER ADAMTSL2 CCN3 SORL1

6.44e-05347265GO:0090092
GeneOntologyBiologicalProcessnegative regulation of inclusion body assembly

SACS SORL1

1.00e-0412262GO:0090084
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

BMPER ADAMTSL2 CCN3 SORL1

1.51e-04218264GO:0090101
GeneOntologyCellularComponentextracellular matrix

CCN2 BMPER SSPOP MUC5AC ADAMTSL2 CCN3

1.57e-04656276GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

CCN2 BMPER SSPOP MUC5AC ADAMTSL2 CCN3

1.60e-04658276GO:0030312
GeneOntologyCellularComponentlate endosome

WDR91 GRN ATP7A SORL1

9.79e-04348274GO:0005770
MousePhenoabnormal thoracic cage morphology

ZC3HC1 CCN2 BMPER ATP7A SACS SSPOP RNF135

4.63e-06463227MP:0004624
MousePhenoabnormal pectoral girdle bone morphology

CCN2 BMPER ATP7A SACS SSPOP RNF135

5.29e-06301226MP:0004508
MousePhenoabnormal appendicular skeleton morphology

CCN2 BMPER ATP7A SACS SSPOP ADAMTSL2 CCN3 RNF135

3.93e-05896228MP:0009250
MousePhenobrain lesion

ATRN GRN SORL1

6.32e-0550223MP:0021002
MousePhenosmall lung saccule

CCN2 BMPER

6.58e-058222MP:0010827
MousePhenoabnormal ejaculation

GRN ADAMTSL2

1.06e-0410222MP:0001378
MousePhenotau protein deposits

GRN SORL1

1.29e-0411222MP:0004250
MousePhenoabnormal cartilage development

CCN2 BMPER ADAMTSL2 CCN3

1.36e-04172224MP:0000164
MousePhenoabnormal cartilage morphology

CCN2 BMPER ATP7A ADAMTSL2 CCN3

1.46e-04336225MP:0000163
MousePhenoabnormal axial skeleton morphology

ZC3HC1 CCN2 BMPER ATP7A SACS SSPOP ADAMTSL2 CCN3 RNF135

2.00e-041458229MP:0002114
MousePhenoabnormal girdle joint morphology

BMPER CCN3

2.13e-0414222MP:0030818
MousePhenoabnormal respiratory conducting tube morphology

CCN2 ATP7A ADAMTSL2

2.48e-0479223MP:0004391
MousePhenoabnormal penile erection

ATP7A ADAMTSL2

3.56e-0418222MP:0001379
MousePhenoabnormal copulation physiology

ATP7A ADAMTSL2

3.98e-0419222MP:0031627
MousePhenoabnormal sternum morphology

CCN2 SACS SSPOP RNF135

6.11e-04255224MP:0000157
MousePhenoabnormal rib morphology

ZC3HC1 CCN2 BMPER ATP7A

6.29e-04257224MP:0000150
DomainVWFC_1

KCP CCN2 BMPER SSPOP MUC5AC CCN3

9.51e-1236276PS01208
DomainVWC

KCP CCN2 BMPER SSPOP MUC5AC CCN3

1.35e-1138276SM00214
DomainVWFC_2

KCP CCN2 BMPER SSPOP MUC5AC CCN3

1.35e-1138276PS50184
DomainVWF_dom

KCP CCN2 BMPER SSPOP MUC5AC CCN3

2.55e-1142276IPR001007
DomainVWC

KCP CCN2 BMPER MUC5AC CCN3

4.10e-1028275PF00093
DomainUnchr_dom_Cys-rich

KCP BMPER SSPOP MUC5AC

2.45e-0913274IPR014853
DomainC8

KCP BMPER SSPOP MUC5AC

2.45e-0913274SM00832
DomainTIL_dom

KCP BMPER SSPOP MUC5AC

3.43e-0914274IPR002919
DomainVWFD

KCP BMPER SSPOP MUC5AC

6.23e-0916274PS51233
DomainVWD

KCP BMPER SSPOP MUC5AC

6.23e-0916274SM00216
DomainVWF_type-D

KCP BMPER SSPOP MUC5AC

6.23e-0916274IPR001846
DomainVWD

KCP BMPER SSPOP MUC5AC

6.23e-0916274PF00094
DomainCTCK_1

CCN2 SSPOP MUC5AC CCN3

1.05e-0818274PS01185
DomainCys_knot_C

CCN2 SSPOP MUC5AC CCN3

4.29e-0825274IPR006207
DomainCTCK_2

CCN2 SSPOP MUC5AC CCN3

4.29e-0825274PS01225
DomainTIL

BMPER SSPOP MUC5AC

5.88e-0712273PF01826
DomainC8

BMPER SSPOP MUC5AC

5.88e-0712273PF08742
DomainGlyco_hormone_CN

CCN2 MUC5AC CCN3

1.21e-0615273IPR006208
DomainCys_knot

CCN2 MUC5AC CCN3

1.21e-0615273PF00007
DomainTSP_1

CCN2 SSPOP ADAMTSL2 CCN3

1.95e-0663274PF00090
DomainTSP1

CCN2 SSPOP ADAMTSL2 CCN3

2.21e-0665274SM00209
DomainTSP1_rpt

CCN2 SSPOP ADAMTSL2 CCN3

2.21e-0665274IPR000884
DomainTSP1

CCN2 SSPOP ADAMTSL2 CCN3

2.21e-0665274PS50092
DomainVWC_out

KCP SSPOP MUC5AC

2.57e-0619273SM00215
DomainCT

CCN2 MUC5AC CCN3

4.07e-0622273SM00041
DomainIGFBP_CNN

CCN2 CCN3

2.01e-055272IPR012395
DomainInsulin_GF-bd_Cys-rich_CS

CCN2 CCN3

1.10e-0411272IPR017891
DomainIGFBP_N_1

CCN2 CCN3

1.32e-0412272PS00222
DomainIB

CCN2 CCN3

3.04e-0418272SM00121
DomainEGF_3

ATRN SSPOP ATRNL1 SORL1

3.41e-04235274PS50026
DomainIGFBP_N_2

CCN2 CCN3

3.76e-0420272PS51323
DomainIGFBP-like

CCN2 CCN3

3.76e-0420272IPR000867
DomainIGFBP

CCN2 CCN3

3.76e-0420272PF00219
DomainEGF_2

ATRN SSPOP ATRNL1 SORL1

5.38e-04265274PS01186
DomainEGF_LAM_2

ATRN ATRNL1

8.54e-0430272PS50027
DomainEGF_LAM_1

ATRN ATRNL1

8.54e-0430272PS01248
DomainPlexin_repeat

ATRN ATRNL1

9.72e-0432272IPR002165
DomainPSI

ATRN ATRNL1

9.72e-0432272PF01437
DomainEGF_Lam

ATRN ATRNL1

1.16e-0335272SM00180
DomainLaminin_EGF

ATRN ATRNL1

1.37e-0338272IPR002049
DomainGrowth_fac_rcpt_

ATRN CCN2 CCN3

1.44e-03156273IPR009030
DomainLDLR_class-A_CS

SSPOP SORL1

1.52e-0340272IPR023415
DomainPSI

ATRN ATRNL1

1.83e-0344272IPR016201
DomainLdl_recept_a

SSPOP SORL1

1.92e-0345272PF00057
DomainPSI

ATRN ATRNL1

2.00e-0346272SM00423
Domain-

SSPOP SORL1

2.00e-03462724.10.400.10
Domain-

ATRN ATRNL1

2.18e-03482722.120.10.80
DomainLDLRA_1

SSPOP SORL1

2.18e-0348272PS01209
DomainLDrepeatLR_classA_rpt

SSPOP SORL1

2.27e-0349272IPR002172
DomainLDLa

SSPOP SORL1

2.27e-0349272SM00192
DomainCUB

ATRN ATRNL1

2.27e-0349272PF00431
DomainLDLRA_2

SSPOP SORL1

2.27e-0349272PS50068
DomainCUB

ATRN ATRNL1

2.36e-0350272SM00042
Domain-

ATRN ATRNL1

2.55e-03522722.60.120.290
DomainCUB

ATRN ATRNL1

2.65e-0353272PS01180
DomainKelch-typ_b-propeller

ATRN ATRNL1

2.85e-0355272IPR015915
DomainCUB_dom

ATRN ATRNL1

3.06e-0357272IPR000859
DomainEGF_extracell

ATRN ATRNL1

3.38e-0360272IPR013111
DomainEGF_2

ATRN ATRNL1

3.38e-0360272PF07974
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SSPOP MUC5AC ADAMTSL2

1.15e-0468203M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

SSPOP MUC5AC ADAMTSL2

4.66e-04109203MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

SSPOP MUC5AC ADAMTSL2

4.91e-04111203M27416
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

CCN2 SSPOP ADAMTSL2 CCN3

3.37e-077527420637190
Pubmed

Physical mapping of human loci homologous to the chicken nov proto-oncogene.

CCN2 CCN3

5.80e-0722721334251
Pubmed

Prognostic value of CCN3 in osteosarcoma.

CCN2 CCN3

5.80e-07227218245529
Pubmed

Genetic analysis of attractin homologs.

ATRN ATRNL1

5.80e-07227218064672
Pubmed

Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein.

CCN2 CCN3

5.80e-07227221209863
Pubmed

Urinary mRNA expression of CCN2/CCN3 as a noninvasive marker for monitoring glomerular structure changes in nondiabetic chronic kidney disease.

CCN2 CCN3

5.80e-07227223061738
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ATRN SSPOP ATRNL1 ADAMTSL2

1.30e-061052749628581
Pubmed

Differential expression of CCN family members CYR611, CTGF and NOV in gastric cancer and their association with disease progression.

CCN2 CCN3

1.74e-06327227633176
Pubmed

Three members of the connective tissue growth factor family CCN are differentially regulated by mechanical stress.

CCN2 CCN3

1.74e-06327215053922
Pubmed

Myeloid Zinc Finger 1 (MZF-1) Regulates Expression of the CCN2/CTGF and CCN3/NOV Genes in the Hematopoietic Compartment.

CCN2 CCN3

1.74e-06327225899830
Pubmed

The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling.

CCN2 CCN3

1.74e-0632729927660
Pubmed

Genetic and phenotypic studies of the dark-like mutant mouse.

ATRN ATRNL1

5.80e-06527218821597
Pubmed

Emerging role of CCN family proteins in tumorigenesis and cancer metastasis (Review).

CCN2 CCN3

8.69e-06627226498181
Pubmed

Impaired intervertebral disc development and premature disc degeneration in mice with notochord-specific deletion of CCN2.

CCN2 CCN3

1.22e-05727223839921
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

SSPOP MUC5AC ATRNL1

2.30e-057127333541421
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ATRN GRN CCN2 BMPER ACLY CCN3 SORL1

2.79e-05120127735696571
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

GRN CCN2 BMPER CCN3

3.89e-0524827424006456
Pubmed

Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage.

CCN2 CCN3

4.50e-051327218597638
Pubmed

Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification.

CCN2 ATRNL1

4.50e-051327218245842
Pubmed

Activation of the NF-kappaB pathway by caspase 8 and its homologs.

RNF135 MAP3K14

6.06e-051527211002417
Pubmed

Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity.

BMPER ATP7A

6.92e-051627219627984
Pubmed

Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors.

CCN2 CCN3

9.84e-051927228202523
Pubmed

Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior.

CCN2 SORL1

1.45e-042327220445055
Pubmed

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis.

KCP BMPER

1.72e-042527217035289
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ATRN OR2K2 GRN SSPOP ACLY

2.30e-0473627529676528
Pubmed

YAP and TAZ are required for the postnatal development and the maintenance of the structural integrity of the oviduct.

CCN2 CCN3

2.33e-042927232520726
Pubmed

The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex.

CCN2 SORL1

2.49e-043027219409883
Pubmed

Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors.

CCN2 CCN3

2.49e-043027235830813
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

SACS SORL1

2.66e-043127227798109
Pubmed

TBX1 is required for normal stria vascularis and semicircular canal development.

ATRN GRN

2.66e-043127231550482
Pubmed

TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme.

BMPER CCN3

7.23e-045127230478225
InteractionASIP interactions

ATRN GRN SORL1

1.19e-0616273int:ASIP
CytobandEnsembl 112 genes in cytogenetic band chr7q32

KCP ZC3HC1

1.50e-0397272chr7q32
CytobandEnsembl 112 genes in cytogenetic band chr17q21

GRN ACLY MAP3K14

2.64e-03473273chr17q21
GeneFamilyCYR61/CTGF/NOV matricellular proteins

CCN2 CCN3

1.92e-0562121046
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

ATRN ATRNL1

1.03e-03412121298
CoexpressionNABA_ECM_GLYCOPROTEINS

KCP CCN2 BMPER SSPOP CCN3

1.38e-06191275MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

KCP CCN2 BMPER SSPOP CCN3

1.57e-06196275M3008
CoexpressionNABA_CORE_MATRISOME

KCP CCN2 BMPER SSPOP CCN3

7.49e-06270275MM17057
CoexpressionNABA_CORE_MATRISOME

KCP CCN2 BMPER SSPOP CCN3

8.19e-06275275M5884
CoexpressionBILD_SRC_ONCOGENIC_SIGNATURE

SACS ACLY SORL1

3.05e-0559273M116
CoexpressionGSE17721_CTRL_VS_CPG_0.5H_BMDC_UP

ATP7A ACLY WDFY1 RNF135

4.93e-05199274M3754
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN

HINFP ATRN GRN SORL1

4.93e-05199274M9913
CoexpressionGSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP

WDR91 CCN2 ATRNL1 SORL1

5.03e-05200274M7490
CoexpressionGSE8621_LPS_PRIMED_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN

GRN SACS ACLY SORL1

5.03e-05200274M6975
CoexpressionNABA_MATRISOME

KCP CCN2 BMPER SSPOP MUC5AC ADAMTSL2 CCN3

5.51e-051008277MM17056
CoexpressionNABA_MATRISOME

KCP CCN2 BMPER SSPOP MUC5AC ADAMTSL2 CCN3

6.16e-051026277M5889
CoexpressionKANG_CISPLATIN_RESISTANCE_UP

GRN ATP7A

2.12e-0421272M2767
ToppCell3'_v3-blood-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|blood / Manually curated celltypes from each tissue

SAXO2 CCN2 BMPER

7.82e-051382739f8389a34c400a6b2b9bf6cef3a71499cc945e35
ToppCellAdult-Mesenchymal-myofibroblast_cell-D122|Adult / Lineage, Cell type, age group and donor

CCN2 BMPER ADAMTSL2

1.17e-04158273410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 SACS CCN3

1.19e-041592739f6607e395bcca9cb1c83199bdbbaaa62a93938d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 SACS CCN3

1.19e-04159273c8b42ebc25ebcc450832096fbffaa5c5f5fe88e7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

1.26e-041622735f009b231f21861afee9cc0c569082e1135f929c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

1.26e-04162273b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GEMIN4 CCN2 BMPER

1.35e-0416627337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GEMIN4 CCN2 BMPER

1.35e-0416627381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

1.43e-041692736ff1172da690ca17f7108f1617b255b766971a57
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN2 BMPER SACS

1.45e-0417027350c6c571591aa4b218caefe5778c570c809f567e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN2 BMPER SACS

1.45e-041702738fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN2 BMPER SACS

1.45e-041702733232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

CCN2 BMPER ATRNL1

1.53e-0417327375e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CCN2 BMPER ATRNL1

1.53e-0417327326e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC2|lymph-node_spleen / Manually curated celltypes from each tissue

GRN MUC5AC CCN3

1.61e-0417627372a3bbab0540ae3e3c94b9573cdb9298a024dbc4
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCN2 BMPER ATRNL1

1.63e-04177273b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCellBAL-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

GEMIN4 WDR91 ATP7A

1.69e-0417927368511e87b12b8253de7771e5ccfc5869248b8450
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

1.74e-041812736d1f1ad35778a2a227f966f11f6edd8e89452576
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN2 BMPER ADAMTSL2

1.77e-04182273dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

1.77e-0418227344764676ed3f51ba171ce63f669390392fa50a43
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN2 BMPER ADAMTSL2

1.77e-04182273c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

1.77e-04182273d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCN2 BMPER ADAMTSL2

1.83e-04184273924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

CCN2 BMPER ADAMTSL2

1.92e-04187273e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

CCN2 BMPER ADAMTSL2

1.92e-0418727392d468dde81125d51daf7abd4703741abe1ab91c
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CCN2 ATRNL1 ADAMTSL2

1.95e-04188273c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCN2 BMPER ADAMTSL2

2.04e-04191273beb5bb42bd53bce01339da9110d374901548793c
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCN2 BMPER ADAMTSL2

2.04e-041912736609d85fd2577633dcc067507304a6f9e5865ca3
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BMPER ATRNL1 ADAMTSL2

2.08e-04192273c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP BMPER ADAMTSL2

2.08e-04192273671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP BMPER ADAMTSL2

2.08e-04192273840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BMPER ATRNL1 ADAMTSL2

2.08e-041922734c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CCN2 BMPER ADAMTSL2

2.11e-041932735896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.11e-041932735b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.11e-04193273c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CCN2 BMPER ADAMTSL2

2.11e-041932735e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRN ADAMTSL2 SORL1

2.11e-04193273697518bab1338dc441b2d93b410d957e692f20e6
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BMPER ATRNL1 ADAMTSL2

2.11e-04193273e2b455387d1de7812305200a2041a0f4759a6f54
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCN2 BMPER ADAMTSL2

2.11e-04193273b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.14e-04194273ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BMPER ATRNL1 ADAMTSL2

2.14e-04194273fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCellControl-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

CCN2 BMPER ADAMTSL2

2.14e-041942733c2266772c5b56e8e02a461e5193e29588028ee9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.14e-04194273240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellControl-Stromal-Myofibroblast|Control / Disease state, Lineage and Cell class

CCN2 BMPER ADAMTSL2

2.17e-04195273ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCellbackground-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

CCN2 BMPER ATRNL1

2.17e-04195273c7d60dabfc7cb310e002cab10003dadfcc34fe33
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.17e-04195273d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.17e-04195273783bfa8110161cbd6def50ce849cae676c39c458
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.17e-04195273cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.17e-0419527344d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

CCN2 BMPER ADAMTSL2

2.17e-04195273aa0add081881d349099d12efca5cdee098038d4e
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BMPER ADAMTSL2 SORL1

2.20e-041962736730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.20e-04196273ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.20e-0419627330ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.20e-041962733a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellNasal_Brush-Epithelial-Goblet_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

GRN MUC5AC SORL1

2.20e-04196273e16f0831f1f677b28e4a8014f0aede7e713d4f04
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

CCN2 BMPER ATRNL1

2.20e-04196273e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.20e-04196273bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BMPER ADAMTSL2 SORL1

2.20e-0419627321dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCellNasal_Brush-Epithelial-Goblet_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

GRN MUC5AC SORL1

2.20e-0419627371e88d9ca28168732bd91f2d4f8f53bb4187963a
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ATRN SAXO2 MUC5AC

2.24e-041972735c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.24e-0419727309946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SSPOP ADAMTSL2 SORL1

2.24e-04197273b597c292fc1cb381a4325fed15a32966c38def28
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN2 ADAMTSL2 CCN3

2.24e-04197273c29ed0e706999d4c2b93e6e3bf46c42aeceb4813
ToppCellBronchial_Brush-Epithelial-Club|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

GRN MUC5AC SORL1

2.27e-0419827361292a2b5aacb6080a679a31b70a211bdec59a3b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN2 ATRNL1 ADAMTSL2

2.27e-0419827379576525a10ed3e3a9d1608077cd16ecda23376f
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WDR91 CCN2 BMPER

2.27e-0419827308d393853e195a7eacace454153e425a273e2d23
ToppCellBronchial_Brush-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

GRN MUC5AC SORL1

2.31e-0419927353b87edccc89a3e8a6c5166472f9ef24fcba416c
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WDR91 CCN2 BMPER

2.34e-04200273251fd2923f108cd2086961d897244b392c32ad54
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCN2 BMPER ADAMTSL2

2.34e-0420027334f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCelldistal-mesenchymal-Myofibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WDR91 CCN2 BMPER

2.34e-0420027361854a459385cd9295be37157a8f81a2c227dff3
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Sphkap|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

OR2K2 MUC5AC

5.24e-0456272af55596513ddbe60b08648b27e41a7b65e3da58c
ComputationalIGFBPs.

CCN2 CCN3

1.36e-0412162MODULE_190
ComputationalGenes in the cancer module 474.

CCN2 CCN3

2.79e-0417162MODULE_474
ComputationalNeighborhood of WNT1

BMPER ATRNL1 MAP3K14

4.89e-04107163MORF_WNT1
ComputationalNeighborhood of LCAT

BMPER ATRNL1 MAP3K14

9.22e-04133163MORF_LCAT
ComputationalNeighborhood of EPHA7

BMPER ATRNL1 MAP3K14

1.05e-03139163MORF_EPHA7
DiseaseGrowth Disorders

ATP7A ADAMTSL2 RNF135

4.25e-0636263C0018273
DiseaseInherited neuropathies

ATP7A SACS

5.70e-0440262C0598589
DiseaseAlzheimer disease

GRN BMPER HTR1E SORL1

8.09e-04485264MONDO_0004975
Diseasepulmonary fibrosis (biomarker_via_orthology)

CCN2 MUC5AC

8.91e-0450262DOID:3770 (biomarker_via_orthology)
Diseaseinterstitial lung disease

HTR1E MUC5AC

1.59e-0367262EFO_0004244
Diseasejoint damage measurement

ATRNL1 MAP3K14

1.64e-0368262EFO_0005413
DiseaseNerve Degeneration

ATRN GRN

2.43e-0383262C0027746
Diseaseupper face morphology measurement

HTR1E CCN3

3.30e-0397262EFO_0010949
Diseasegallstones

MUC5AC CCN3

4.07e-03108262EFO_0004210
DiseaseLeft-Sided Heart Failure

CCN2 ACLY

4.22e-03110262C0023212
DiseaseMyocardial Failure

CCN2 ACLY

4.22e-03110262C1959583
DiseaseHeart Failure, Right-Sided

CCN2 ACLY

4.22e-03110262C0235527
DiseaseCongestive heart failure

CCN2 ACLY

4.22e-03110262C0018802
DiseaseHeart failure

CCN2 ACLY

4.22e-03110262C0018801
DiseaseHeart Decompensation

CCN2 ACLY

4.22e-03110262C1961112
Diseasenon-alcoholic fatty liver disease, type 2 diabetes mellitus

ATRN HTR1E

4.22e-03110262EFO_0003095, MONDO_0005148

Protein segments in the cluster

PeptideGeneStartEntry
FSTCCVMVDGSWGCC

GRN

136

P28799
EVWLSVDMTCCTCSI

HTR1E

96

P28566
TISVEGMTCNSCVWT

ATP7A

11

Q04656
DCTSGSSECMWCSNM

ATRN

941

O75882
MSEWSECTAKCGERS

ADAMTSL2

691

Q86TH1
GCNTCTCDSRMWRCT

MUC5AC

881

P98088
GEMWSSINCTICACV

BMPER

311

Q8N8U9
SRMEGSSTCFWAESC

CARD14

796

Q9BXL6
CIEQTTEWTACSKSC

CCN3

206

P48745
VQTTEWSACSKTCGM

CCN2

201

P29279
SNGMECMWCSSTKRC

ATRNL1

901

Q5VV63
CMWCSSTKRCVDSNA

ATRNL1

906

Q5VV63
MSICSSACTDSWRVV

KRTAP10-10

6

P60014
QCEWGSCSFVCSTME

HINFP

16

Q9BQA5
KTVECTTWLLCTCMD

SACS

1811

Q9NZJ4
RSCDAKVDVWSSCCM

MAP3K14

571

Q99558
CARMATVSWVTGCLT

OR2K2

141

Q8NGT1
GRTMDSCCVEWKGTS

RNF135

341

Q8IUD6
CSSGTCVMDTWVCDG

SORL1

1426

Q92673
MACTSERCPVACGWS

SSPOP

2976

A2VEC9
GERWTVDTCTSCSCM

KCP

1161

Q6ZWJ8
VDTCTSCSCMAGTVR

KCP

1166

Q6ZWJ8
VCWCIGTCATMFSSE

ACLY

741

P53396
GWVTVECDMLKCSSC

ZC3HC1

106

Q86WB0
MRSWCLCQICSCGSD

SAXO2

6

Q658L1
TVDWSTAMDCGTCLT

WDR91

716

A4D1P6
STGHDKCVSWMCTRS

WDFY1

131

Q8IWB7
LAWMECCCVSSGISE

GEMIN4

816

P57678
SCSAPMVCWTVCSCL

NLRP13

421

Q86W25