Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainArm

TNPO2 APC ODAD2 KPNB1

4.16e-0631664PF00514
DomainArmadillo

TNPO2 APC ODAD2 KPNB1

2.26e-0547664IPR000225
DomainHJURP_C

MEF2A MEF2C

7.35e-054662IPR022102
DomainHJURP_C

MEF2A MEF2C

7.35e-054662PF12347
DomainMADS_MEF2-like

MEF2A MEF2C

7.35e-054662IPR033896
DomainMADS

MEF2A MEF2C

1.83e-046662SM00432
DomainMADS_BOX_1

MEF2A MEF2C

1.83e-046662PS00350
DomainSRF-TF

MEF2A MEF2C

1.83e-046662PF00319
DomainMADS_BOX_2

MEF2A MEF2C

1.83e-046662PS50066
DomainTF_MADSbox

MEF2A MEF2C

2.55e-047662IPR002100
DomainARM

APC ODAD2 KPNB1

3.79e-0440663SM00185
DomainRan_BP1

RANBP2 RANBP3

7.93e-0412662PF00638
DomainRANBD1

RANBP2 RANBP3

7.93e-0412662PS50196
DomainRanBD

RANBP2 RANBP3

9.36e-0413662SM00160
DomainRan_bind_dom

RANBP2 RANBP3

9.36e-0413662IPR000156
DomainIMPORTIN_B_NT

TNPO2 KPNB1

1.09e-0314662PS50166
Domain-

TNPO2 APC ODAD2 HECTD1 KPNB1

1.12e-032226651.25.10.10
DomainHEAT

TNPO2 ODAD2 KPNB1

1.13e-0358663IPR000357
DomainARM-type_fold

TNPO2 EIF2B5 APC ODAD2 HECTD1 KPNB1

1.24e-03339666IPR016024
DomainIBN_N

TNPO2 KPNB1

1.25e-0315662PF03810
DomainIBN_N

TNPO2 KPNB1

1.43e-0316662SM00913
DomainImportin-beta_N

TNPO2 KPNB1

1.62e-0317662IPR001494
DomainHEAT_REPEAT

TNPO2 ODAD2 KPNB1

1.95e-0370663PS50077
DomainVWC_out

JAG2 MUC2

2.02e-0319662SM00215
DomainPWWP

PWWP2B HDGFL2

2.24e-0320662SM00293
DomainARM-like

TNPO2 APC ODAD2 HECTD1 KPNB1

2.65e-03270665IPR011989
DomainPWWP

PWWP2B HDGFL2

2.97e-0323662PF00855
DomainPWWP_dom

PWWP2B HDGFL2

2.97e-0323662IPR000313
DomainPWWP

PWWP2B HDGFL2

3.23e-0324662PS50812
DomainBromodomain_CS

BPTF SMARCA4

3.78e-0326662IPR018359
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NCOA2 UBE2O APPL2 LEO1 TNPO2 ARID5B APC SMARCA4 ERC2 SPARCL1 RILPL1 HECTD1 LRP1B ST18 METAP2 PCNT KPNB1

3.04e-101285681735914814
Pubmed

Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.

RANBP2 RANBP3 STON2 TTYH3 MEF2A MEF2C RBM17

2.16e-0911068737219487
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 RANBP3 ARID5B SMARCA4 MEF2A CASZ1 RBM17

9.68e-0726868733640491
Pubmed

Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.

SMARCA4 MEF2A MEF2C

1.55e-061268316424906
Pubmed

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.

NCOA2 MEF2A MEF2C

2.56e-061468312130539
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

BPTF GTF2E1 LEO1 SMARCA4 SALL4 RBM17

2.97e-0620368622083510
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

BPTF RANBP2 USP42 SMARCA4 SALL4 HDGFL2 CCDC9 KPNB1

3.75e-0646968827634302
Pubmed

Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice.

MEF2A MEF2C

3.77e-06268216469744
Pubmed

Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.

MEF2A MEF2C

3.77e-06268225336633
Pubmed

Dietary induction of colonic tumors in a mouse model of sporadic colon cancer.

APC MUC2

3.77e-06268218829535
Pubmed

Winnie-APCMin/+ Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation.

APC MUC2

3.77e-06268232340123
Pubmed

Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.

APC MUC2

3.77e-06268218794118
Pubmed

RanGTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex.

RANBP2 KPNB1

3.77e-0626829398662
Pubmed

Regulation of myocyte enhancer factor-2 transcription factors by neurotoxins.

MEF2A MEF2C

3.77e-06268221741404
Pubmed

PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.

APC MUC2

3.77e-06268219232344
Pubmed

Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma.

MEF2A MEF2C

3.77e-06268217611778
Pubmed

Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma.

BPTF SMARCA4

3.77e-06268231065107
Pubmed

Autism-Associated Chromatin Regulator Brg1/SmarcA4 Is Required for Synapse Development and Myocyte Enhancer Factor 2-Mediated Synapse Remodeling.

SMARCA4 MEF2C

3.77e-06268226459759
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 BPTF RANBP2 TNPO2 MCM3AP ARID5B SMARCA4

5.74e-0635168738297188
Pubmed

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.

RILPL1 ITGA7 MEF2A MEF2C

6.00e-066068419075228
Pubmed

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors.

SALL4 ITGA7 MEF2C KPNB1

6.41e-066168419796622
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

BPTF EHBP1L1 RANBP3 INSRR APC METAP2 PCNT

6.77e-0636068733111431
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

BPTF RANBP2 LEO1 USP42 ARID5B SMARCA4 MPHOSPH8 E4F1 HDGFL2 CASZ1 KPNB1 RBM17

7.09e-061294681230804502
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

BPTF RANBP2 EHBP1L1 USP42 RBM12B MYO18A APC SMARCA4 MPHOSPH8 KPNB1 RBM17

7.60e-061082681138697112
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

BPTF LEO1 SMARCA4 HDGFL2 PCNT RBM17

1.00e-0525168631076518
Pubmed

Deletion of TNF in Winnie-APCMin/+ Mice Reveals Its Dual Role in the Onset and Progression of Colitis-Associated Colorectal Cancer.

APC MUC2

1.13e-05368236499472
Pubmed

The nuclear localization domain of the MEF2 family of transcription factors shows member-specific features and mediates the nuclear import of histone deacetylase 4.

MEF2A MEF2C

1.13e-05368211792813
Pubmed

An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133.

MEF2A MEF2C

1.13e-05368218093911
Pubmed

MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.

MEF2A MEF2C

1.13e-05368224043307
Pubmed

Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.

MEF2A MEF2C

1.13e-05368215834131
Pubmed

Kaiso-deficient mice show resistance to intestinal cancer.

APC MUC2

1.13e-05368216354691
Pubmed

miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis.

SMARCA4 SALL4

1.13e-05368232320856
Pubmed

In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival.

MEF2A MEF2C

1.13e-05368222496871
Pubmed

Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo.

MEF2A MEF2C

1.13e-05368226286136
Pubmed

The coactivator-associated arginine methyltransferase is necessary for muscle differentiation: CARM1 coactivates myocyte enhancer factor-2.

NCOA2 MEF2C

1.13e-05368211713257
Pubmed

MEF2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury.

MEF2A MEF2C

1.13e-05368233315889
Pubmed

Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c.

MEF2A MEF2C

1.13e-05368227989458
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

BPTF RANBP2 ARID5B SMARCA4 HDGFL2

1.17e-0515068528242625
Pubmed

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation.

SMARCA4 MEF2A MEF2C

1.40e-052468337543677
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

RANBP2 MCM3AP APC KPNB1

1.62e-057768424927568
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BPTF RANBP2 PWWP2B LEO1 USP42 EIF2B5 MYO18A SMARCA4 CCDC9

1.95e-0577468915302935
Pubmed

Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes.

MEF2A MEF2C

2.25e-05468215140898
Pubmed

Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.

MEF2A MEF2C

2.25e-05468222764880
Pubmed

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import.

RANBP2 KPNB1

2.25e-0546828909533
Pubmed

Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23.

MEF2A MEF2C

2.25e-0546828575763
Pubmed

Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors.

MEF2A MEF2C

2.25e-05468210330143
Pubmed

Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.

SMARCA4 E4F1

2.25e-05468233692124
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

JAG2 MUC2

2.25e-05468222691042
Pubmed

Nup358 interacts with APC and plays a role in cell polarization.

RANBP2 APC

2.25e-05468219654215
Pubmed

MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation.

MEF2A MEF2C

2.25e-05468225416778
Pubmed

Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene.

MEF2A MEF2C

2.25e-05468210207130
Pubmed

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins.

MEF2A MEF2C

2.25e-0546828548800
Pubmed

Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory.

MEF2A MEF2C

2.25e-05468221531906
Pubmed

Brahma safeguards canalization of cardiac mesoderm differentiation.

SMARCA4 MEF2C

2.25e-05468235082446
Pubmed

Requirement of MEF2A, C, and D for skeletal muscle regeneration.

MEF2A MEF2C

2.25e-05468224591619
Pubmed

Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation.

MEF2A MEF2C

2.25e-0546827643214
Pubmed

TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.

MEF2A MEF2C

2.25e-05468212061776
Pubmed

GTP hydrolysis links initiation and termination of nuclear import on the nucleoporin nup358.

RANBP2 KPNB1

2.25e-05468210473610
Pubmed

Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice.

MEF2A MEF2C

2.25e-05468231420455
Pubmed

Early expression of the different isoforms of the myocyte enhancer factor-2 (MEF2) protein in myogenic as well as non-myogenic cell lineages during mouse embryogenesis.

MEF2A MEF2C

2.25e-0546828817457
Pubmed

Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR.

TNPO2 KPNB1

2.25e-05468215037768
Pubmed

Colorectal cancer in mice genetically deficient in the mucin Muc2.

APC MUC2

2.25e-05468211872843
Pubmed

Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation.

MEF2A MEF2C

2.25e-05468211809751
Pubmed

Brg1 is required to maintain colorectal cancer stem cells.

APC SMARCA4

2.25e-05468234415580
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

BPTF GTF2E1 UBE2O SMARCA4 MPHOSPH8 HDGFL2 METAP2 CASZ1

2.45e-0560868836089195
Pubmed

Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.

MEF2A MEF2C

3.75e-05568219093215
Pubmed

Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.

MEF2A MEF2C

3.75e-05568212694204
Pubmed

Expression of MEF2 genes during human cardiac development.

MEF2A MEF2C

3.75e-05568210458488
Pubmed

A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.

EIF2B5 APC

3.75e-05568231685988
Pubmed

Control of the SOST bone enhancer by PTH using MEF2 transcription factors.

MEF2A MEF2C

3.75e-05568217696759
Pubmed

Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation.

MEF2A MEF2C

3.75e-05568215084602
Pubmed

The MEF2B homologue differentially expressed in mouse embryonal carcinoma cells.

MEF2A MEF2C

3.75e-0556827646512
Pubmed

RanGTP mediates nuclear pore complex assembly.

RANBP2 KPNB1

3.75e-05568212894213
Pubmed

HDAC4 integrates PTH and sympathetic signaling in osteoblasts.

MEF2A MEF2C

3.75e-05568224934156
Pubmed

Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1.

MEF2A MEF2C

3.75e-0556829753748
Pubmed

HRP2-DPF3a-BAF complex coordinates histone modification and chromatin remodeling to regulate myogenic gene transcription.

SMARCA4 HDGFL2

3.75e-05568232459350
Pubmed

Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors.

MEF2A MEF2C

3.75e-05568220833138
Pubmed

Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle.

MEF2A MEF2C

3.75e-0556828993831
Pubmed

Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.

MEF2A MEF2C

3.75e-05568223511190
Pubmed

Regulatory role of MEF2D in serum induction of the c-jun promoter.

MEF2A MEF2C

3.75e-0556827760790
Pubmed

Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells.

NCOA2 SMARCA4

3.75e-05568214966121
Pubmed

Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family.

MEF2A MEF2C

3.75e-0556828900141
Pubmed

Regulation of the MEF2 family of transcription factors by p38.

MEF2A MEF2C

3.75e-0556829858528
Pubmed

Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'-monooxygenase gene expression.

MEF2A MEF2C

3.75e-05568216504037
Pubmed

MEF2 transcription factors are key regulators of sprouting angiogenesis.

MEF2A MEF2C

3.75e-05568227898394
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BPTF RANBP2 UBE2O MCM3AP SMARCA4 HECTD1 PCNT KPNB1

4.06e-0565368822586326
Pubmed

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.

APPL2 OGFR TNPO2 REM2 HDGFL2 CCDC9

4.65e-0533068621044950
Pubmed

Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases.

MEF2A MEF2C

5.62e-05668210737771
Pubmed

The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2.

MEF2A MEF2C

5.62e-05668222135324
Pubmed

Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation.

MEF2A MEF2C

5.62e-05668215173318
Pubmed

Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum.

APC MUC2

5.62e-05668216142311
Pubmed

Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import.

RANBP3 KPNB1

5.62e-05668212176322
Pubmed

TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2.

MEF2A MEF2C

5.62e-05668220399744
Pubmed

Karyopherin beta2 mediates nuclear import of a mRNA binding protein.

RANBP2 KPNB1

5.62e-0566829144189
Pubmed

The expression of MEF2 genes is implicated in CNS neuronal differentiation.

MEF2A MEF2C

5.62e-0566829013788
Pubmed

Phosphorylation of Crm1 by CDK1-cyclin-B promotes Ran-dependent mitotic spindle assembly.

RANBP2 KPNB1

5.62e-05668223729730
Pubmed

LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.

BPTF APC

5.62e-05668230224759
Pubmed

Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function.

NCOA2 MEF2C

5.62e-05668224811170
Pubmed

Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins.

MEF2A MEF2C

5.62e-05668211160896
Pubmed

Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import.

RANBP2 KPNB1

5.62e-05668211266456
InteractionHDAC1 interactions

BPTF RANBP2 PWWP2B TNPO2 ARID5B APC SMARCA4 SALL4 E4F1 HECTD1 MEF2A CASZ1 PCNT KPNB1

1.35e-0511086714int:HDAC1
InteractionPDCD7 interactions

LEO1 MCM3AP HECTD1 METAP2

4.42e-0559674int:PDCD7
InteractionMYOD1 interactions

NCOA2 BPTF UBE2O SMARCA4 MEF2A MEF2C

4.51e-05194676int:MYOD1
InteractionTNFSF13B interactions

RANBP2 TNPO2 EIF2B5 ITGA7 KPNB1

4.76e-05119675int:TNFSF13B
InteractionSUZ12 interactions

BPTF RANBP2 UBE2O USP42 TNPO2 SMARCA4 SALL4 HECTD1 PCNT KPNB1

4.97e-056446710int:SUZ12
InteractionPNN interactions

UBE2O LEO1 RBM12B MCM3AP RALYL HECTD1 CCDC9

6.38e-05302677int:PNN
InteractionNTN5 interactions

JAG2 APC LRP1B

6.76e-0524673int:NTN5
InteractionDPPA3 interactions

RANBP2 TNPO2 MCM3AP KPNB1

7.30e-0567674int:DPPA3
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2A MEF2C

3.96e-054472649
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2A MEF2C

6.58e-0554721086
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

APC ODAD2 KPNB1

1.89e-0443473409
GeneFamilyArmadillo repeat containing|Importins

TNPO2 KPNB1

9.85e-0418472596
CoexpressionKAMMINGA_SENESCENCE

GTF2E1 PSD ARHGEF10L KPNB1

3.18e-0639684MM878
CoexpressionKAMMINGA_SENESCENCE

GTF2E1 PSD ARHGEF10L KPNB1

3.53e-0640684M2037
CoexpressionDING_LUNG_CANCER_BY_MUTATION_RATE

MAST4 INSRR LRP1B

1.84e-0520683M1189
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

NCOA2 RANBP2 APPL2 LEO1 TRIM56 STON2 NHS ERC2 SALL4 MPHOSPH8 ST18 MINDY1 PCNT KPNB1

1.54e-069836614Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

NCOA2 RANBP2 APPL2 LEO1 RBM12B TRIM56 NHS ERC2 MPHOSPH8 PCNT KPNB1

5.01e-066546611Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#5_top-relative-expression-ranked_200

USP31 APC SALL4 KPNB1

6.32e-0569664gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

NCOA2 RANBP2 APPL2 LEO1 ERC2 MPHOSPH8 KPNB1

7.02e-05328667Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 RALYL NHS LRP1B CASZ1 ARHGEF10L

5.06e-0719368682e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 RALYL NHS LRP1B CASZ1 ARHGEF10L

5.37e-071956866477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell3'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO18A IL20RA SPARCL1 CFAP70 PPP1R15A

5.56e-06166685b64ab3d13b76bba3c305ebbfc96f983cd6ca30c9
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG2 USP31 MAST4 INSRR ST18

7.81e-06178685fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

RALYL ERC2 RILPL1 ITGA7 CASZ1

1.02e-051886856d249fe92d51a19da19ec14bb2262d394255d577
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID5B NHS CBARP ST18 MEF2C

1.04e-05189685fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

MAST4 RALYL ERC2 RILPL1 CASZ1

1.10e-051916855d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)|Adult / Lineage, Cell type, age group and donor

BMP2K STON2 TTYH3 MEF2C ARHGEF10L

1.15e-0519368531c0978ba78c9516d498aec0798902e57555e557
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

JAG2 MAST4 PSD SPARCL1 MEF2C

1.37e-0520068561d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

BPTF MAST4 SPARCL1 MEF2C PCNT

1.37e-05200685dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellMacroglial-Astrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAST4 BMP2K STON2 SPARCL1 ITGA7

1.37e-05200685941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAST4 BMP2K STON2 SPARCL1 ITGA7

1.37e-05200685d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAST4 BMP2K STON2 SPARCL1 ITGA7

1.37e-05200685f861509b54185d89931db64da1b9d81986cc7938
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAST4 BMP2K STON2 SPARCL1 ITGA7

1.37e-0520068516f468217427921fa18c6d078ffa990eb019b257
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAST4 BMP2K STON2 SPARCL1 ITGA7

1.37e-052006850442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

MAST4 BMP2K STON2 SPARCL1 ITGA7

1.37e-0520068501819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

JAG2 MAST4 PSD SPARCL1 MEF2C

1.37e-052006855c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellCOVID|World / Condition, Cell_class and T cell subcluster

EHBP1L1 BMP2K MEF2A MEF2C ARHGEF10L

1.37e-0520068504a932fe2431e7886120c219ce666f90d3030a1c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RALYL METAP2 CASZ1 ARHGEF10L

8.40e-0515168410da94037225a71844281ddcb395072250a78094
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

USP42 ERC2 ST18 ARHGEF10L

1.03e-041596842f6c60ddff2208a68146f9786143d9aefd528840
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP42 ERC2 ST18 ARHGEF10L

1.03e-04159684ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

MAST4 TNPO2 MCM3AP CASZ1

1.33e-041706844a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NHS SPARCL1 ITGA7 ARHGEF10L

1.42e-04173684cb6389536195443633adb06e5f1b7483530773d1
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSD RALYL STON2 CBARP

1.45e-04174684742c73c9e090848b464323cb17579b86658c6792
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2O STON2 PPP1R15A STX11

1.45e-04174684a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSD RALYL STON2 CBARP

1.45e-041746847fed9722e64c60843092f2ba71256e3043011ef6
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2O STON2 PPP1R15A STX11

1.45e-041746846cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2O STON2 PPP1R15A STX11

1.45e-041746844b8bc5568e36031c8ecf001bb646809038c23919
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K APC RILPL1 MEF2C

1.65e-04180684df60970520fba2ac0639faa54096766d07418ca4
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP3 SMARCA4 REM2 ST18

1.72e-04182684d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7|TCGA-Prostate / Sample_Type by Project: Shred V9

UBE2O LEO1 SMARCA4 KPNB1

1.72e-04182684af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP3 SMARCA4 REM2 ST18

1.72e-0418268492f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP3 SMARCA4 REM2 ST18

1.72e-0418268402baca9a72c7b559c3e452693b3b134af804c868
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAST4 SPARCL1 ITGA7 MINDY1

1.76e-04183684807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL4 ODAD2 LRP1B ST18

1.80e-041846842cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APC PPP1R15A MEF2A MEF2C

1.80e-041846841154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL4 ODAD2 LRP1B ST18

1.80e-04184684ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL4 ODAD2 LRP1B ST18

1.80e-041846842b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP2 CBARP TTYH3 MEF2C

1.80e-04184684b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D175|Adult / Lineage, Cell type, age group and donor

BMP2K STON2 TTYH3 MEF2C

1.83e-04185684ab5704b96f1d368911308797d10c7c52766ab134
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

APPL2 BMP2K STON2 MEF2C

1.83e-041856848207f9eff113eed429e961748c6b17d672a13b33
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MAST4 SPARCL1 ITGA7 MINDY1

1.87e-0418668476cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 RALYL NHS TTYH3

1.87e-041866845784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RALYL IL20RA ERC2 ST18

1.87e-04186684b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellfacs-Aorta-Heart-3m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID5B MYO18A SPARCL1 MEF2A

1.91e-04187684df0279b7e94e26f5541b0e2a0ce56befa96ec8ca
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RALYL LRP1B CASZ1 ARHGEF10L

1.95e-041886844154f4787483c7e076e87a187733a9f666742c3d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EHBP1L1 SPARCL1 ITGA7 MEF2C

1.99e-04189684127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP2 LEO1 BMP2K PPP1R15A

1.99e-04189684f01158bb15df3117fae1271bf8cf8c2501422671
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EHBP1L1 SPARCL1 ITGA7 MEF2C

1.99e-041896842cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EHBP1L1 PWWP2B MEF2A MEF2C

2.03e-04190684ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

BMP2K STON2 TTYH3 MEF2C

2.03e-041906842d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

BMP2K ARID5B MEF2A MEF2C

2.03e-041906841e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 RALYL NHS LRP1B

2.03e-04190684cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 RALYL NHS TTYH3

2.07e-041916843c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 RALYL NHS TTYH3

2.07e-041916841c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 NHS LRP1B CASZ1

2.07e-04191684963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell(4)_Endothelial_cells-(41)_EC-arteriolar|World / Cell class and subclass of bone marrow stroma cells in homeostatis

JAG2 MAST4 SPARCL1 MEF2C

2.07e-04191684718c83046668a7c33bd8319b45c56f8edb34cfe7
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

MAST4 SPARCL1 OMD LRP1B

2.11e-041926847e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellImmune-interstitial_macrophage_(C1Q_positive)|World / Lineage, Cell type, age group and donor

BMP2K STON2 TTYH3 MEF2C

2.16e-0419368464d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 RALYL NHS ARHGEF10L

2.16e-041936843866667dd221612589ae50f5c52f73a183a49ce6
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BMP2K STON2 TTYH3 STX11

2.16e-041936842d0dd2671ff27b922eb316f1ed0140353536ef30
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

BMP2K ARID5B MEF2A MEF2C

2.16e-041936847ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell10x5'-Lung-Myeloid_Dendritic-DC2|Lung / Manually curated celltypes from each tissue

ERC2 ST18 MEF2A MEF2C

2.16e-04193684c97f9b13057f803df63c696c6175ef8e0aba6fa7
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BPTF ARID5B MEF2A MEF2C

2.20e-04194684ff661419b697aef51a53fdeac8d37d870d65f491
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 ARID5B HECTD1 MEF2A

2.20e-04194684e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARID5B CBARP ST18 MEF2C

2.20e-0419468436f8ae4f2b3bf802f6ff0e9fc79e7f170f96ae8b
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

BMP2K STON2 TTYH3 MEF2C

2.20e-04194684800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAST4 NHS CASZ1 ARHGEF10L

2.20e-041946845eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PWWP2B BMP2K MEF2A MEF2C

2.20e-04194684d852aebf7a763b9a776c4570711f0c759f591910
ToppCellCTRL-Myeloid-Monocyte_Macrophage|CTRL / Disease state, Lineage and Cell class

ARID5B TTYH3 ST18 MEF2C

2.20e-04194684927480f56cccd3940b689f3c40ee132fe3e63745
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

BMP2K TTYH3 CCDC9 MEF2C

2.20e-0419468458046894446cb250814252a23f60fdd59c114d77
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Syt15_(Medial_habenula)|Thalamus / BrainAtlas - Mouse McCarroll V32

TDRD9 TEX38 INSRR

2.23e-04776837f624e9262bd0dc2ac4176f43c91a4bc0f521fe5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PWWP2B PPP1R15A MEF2A MEF2C

2.24e-04195684481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PWWP2B PPP1R15A MEF2A MEF2C

2.24e-041956846108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K APC MEF2A MEF2C

2.24e-04195684a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellE12.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EHBP1L1 PSD SPARCL1 CASZ1

2.24e-04195684bff7685784688425bebd78b0f284a6d4475a9415
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAST4 RALYL MEF2A MEF2C

2.24e-04195684787e95fb59c40bba784544b662fac37606ae1427
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RANBP2 BMP2K MEF2A MEF2C

2.29e-04196684e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TTYH3 STX11 MEF2C ARHGEF10L

2.33e-04197684321ccd20b0bb03c99a00452ac3c637ee3aa73ecf
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EHBP1L1 SPARCL1 ITGA7 ARHGEF10L

2.38e-04198684bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EHBP1L1 SPARCL1 ITGA7 ARHGEF10L

2.42e-04199684b1753474152b82a0b811b9878c890a359e14919a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

ARID5B SPARCL1 ITGA7 METAP2

2.47e-042006845ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCellCOVID-mono1|COVID / Condition, Cell_class and T cell subcluster

BMP2K MEF2A MEF2C ARHGEF10L

2.47e-04200684bd002c54305c746c07b7418a2084195e9c852ec5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STON2 APC SPARCL1 LRP1B

2.47e-0420068407d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STON2 APC SPARCL1 LRP1B

2.47e-04200684d0812817ef99608994193787a62d39adeb2070ca
ToppCellCOVID-mono1-|COVID / Condition, Cell_class and T cell subcluster

BMP2K MEF2A MEF2C ARHGEF10L

2.47e-04200684445a1aab962673dcc926c33ce9bed5ede9c41c57
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

BPTF MAST4 SPARCL1 MEF2C

2.47e-04200684a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STON2 APC SPARCL1 LRP1B

2.47e-04200684cd54ddf1919c98e84b7e4aba85b374fc8b407206
ComputationalNuclear pore complex.

RANBP2 TNPO2 KPNB1

3.63e-0517423MODULE_352
DrugBretylium tosylate [61-75-6]; Down 200; 9.6uM; PC3; HT_HG-U133A

NCOA2 MAST4 OGFR MCM3AP APC MEF2A MEF2C

2.17e-061996876674_DN
DrugGuanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HG-U133A

JAG2 RNF167 OGFR SMARCA4 CCDC9 CASZ1

2.43e-051936861961_DN
DrugMethylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A

NCOA2 EHBP1L1 MAST4 BMP2K APC CCDC9

2.43e-051936863378_DN
DrugBenfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

EHBP1L1 MAST4 OGFR APC PPP1R15A MEF2C

2.50e-051946862621_UP
DrugAcacetin [480-44-4]; Down 200; 14uM; PC3; HT_HG-U133A

MAST4 BMP2K ARID5B APC PPP1R15A CCDC9

2.57e-051956864324_DN
DrugNiridazole [61-57-4]; Down 200; 18.6uM; HL60; HT_HG-U133A

ARID5B APC PPP1R15A ITGA7 CCDC9 MEF2C

2.65e-051966862440_DN
DrugSulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A

JAG2 EHBP1L1 OGFR RANBP3 MEF2A MINDY1

2.72e-051976862814_DN
Diseasemultiple sclerosis

NCOA2 USP31 SMARCA4 IL20RA HDGFL2 MEF2C KPNB1 RBM17

5.29e-05594668MONDO_0005301
DiseaseRectal Carcinoma

APC MUC2

1.03e-047662C0007113
DiseaseRectal Neoplasms

APC MUC2

1.03e-047662C0034885
DiseaseIntestinal Neoplasms

APC MUC2

3.21e-0412662C0021841
DiseaseIntestinal Cancer

APC MUC2

3.21e-0412662C0346627
Diseasegallbladder cancer (is_implicated_in)

APC LRP1B

3.78e-0413662DOID:3121 (is_implicated_in)
Diseaseimmunoglobulin lambda-like polypeptide 1 measurement

ARID5B MEF2C

5.79e-0416662EFO_0801688
Diseasenighttime rest measurement

MYO18A ERC2

1.32e-0324662EFO_0007827
Diseasebreast cancer (implicated_via_orthology)

APC SMARCA4

1.43e-0325662DOID:1612 (implicated_via_orthology)
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

APC SMARCA4

1.55e-0326662C0009405
Diseasephospholipids:total lipids ratio

BPTF PSD SMARCA4 KPNB1

1.69e-03227664EFO_0020946
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

MEF2A MEF2C

1.79e-0328662DOID:1094 (implicated_via_orthology)
DiseaseHereditary Nonpolyposis Colorectal Cancer

APC SMARCA4

1.92e-0329662C1333990
DiseaseGlioblastoma Multiforme

JAG2 INSRR APC

2.00e-03111663C1621958
Diseasepneumonia, COVID-19

LRP1B ST18 METAP2

2.10e-03113663EFO_0003106, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
PQDDEEAAAPHAAAG

BARGIN

21

Q6ZT62
DNGTHPAQDPDFRGE

CBARP

96

Q8N350
REPAPADGAALEHSE

ARHGEF10L

1191

Q9HCE6
PQGCSDEEDHAEEPS

CASZ1

126

Q86V15
DFNDDDTEPENLGHR

BMP2K

771

Q9NSY1
AADDPENGERESHTP

BPTF

726

Q12830
DSGEEPRGEAEAPHH

RANBP3

36

Q9H6Z4
HPPDEDFRSPQEEDF

RBM12B

821

Q8IXT5
ADHSTEEPAEGGPDA

RALYL

251

Q86SE5
AHGDDDDDGPHFEPV

RANBP2

1161

P49792
EAPNDDEDEGHRSDG

LEO1

111

Q8WVC0
DGDFDCPDHSDEAPL

LRP1B

2866

Q9NZR2
GSHLNGDLDPDDREE

METAP2

11

P50579
PGPAGHAAVREDEED

JAG2

1166

Q9Y219
HEPAEDSDPLSRGDH

MCM3AP

306

O60318
LHPPDAEEDEDDGEF

EIF2B5

451

Q13144
EDHPSSGSDDGDREP

MUC2

1311

Q02817
APDRSDDEHDPLDNT

MYO18A

2016

Q92614
SDEDEAHGPGAPEAR

EHBP1L1

191

Q8N3D4
PDEHPQDTDARDADG

MINDY1

31

Q8N5J2
CDSPDPDADDSVGHS

MEF2C

96

Q06413
PDADDSVGHSPESED

MEF2C

101

Q06413
SNHRPSPDQDDEEGI

ERC2

941

O15083
DGSDREDPRGDFHSP

MEF2A

466

Q02078
SDDSCDGEEPDISPH

PCNT

2111

O95613
PEANPADGSDADEDD

HDGFL2

106

Q7Z4V5
AQEHTDSEEGPEEEP

IL20RA

461

Q9UHF4
SAEEAEDHGRIPDPD

FAM189A2

126

Q15884
DDNFPDDESRHVDLG

HECTD1

2196

Q9ULT8
GDEEEPAQDHQAPEA

CCDC9

441

Q9Y3X0
EEGELNHPEDSEFRN

CFAP70

256

Q5T0N1
QPDDDDGNPNEHRGA

APPL2

646

Q8NEU8
EASEAAEQGRPPEHT

KPNB1

296

Q14974
EQDEAASCPGDPHEE

MAST4

986

O15021
NEGRPESDAADHTGP

MALSU1

76

Q96EH3
SNNDPRFDGEDGDPE

INSRR

666

P14616
DPAQPQADGDDAHEA

ITGA7

741

Q13683
PAPFSEEDEDDVHRC

E4F1

46

Q66K89
PVNDSHGRAPEEGDA

PWWP2B

61

Q6NUJ5
PVNHPGNDEVASEDE

SALL4

46

Q9UJQ4
DSPFPEDDSEGLHSD

MPHOSPH8

271

Q99549
DSEAALGEAESDPHP

PPP1R15A

456

O75807
PDNAHESPEQEGAEG

OMD

396

Q99983
EEEGSPGDPDHEAST

OGFR

311

Q9NZT2
QEREEGHAGPDDNEE

GTF2E1

306

P29083
PHPSLGSGNEDEDDD

PSD

341

A5PKW4
DEHDCEPSDPEQETR

RNF181

6

Q9P0P0
AVSGQREDENPHDGE

TDRD9

576

Q8NDG6
EGETENSDGSPHDDR

NHS

1631

Q6T4R5
EEDEEPPDHRQEASA

ODAD2

431

Q5T2S8
QEEGDEGEPRDHPAS

RNF167

291

Q9H6Y7
PDPDSDDVSEVDARH

SMARCA4

691

P51532
QDAHPDPDANPDAAR

SPINDOC

156

Q9BUA3
DDPDHFGSATLPDDD

STON2

391

Q8WXE9
HSDDGRDKIDDSQPP

ST18

171

O60284
DTPQGRNSDHGEDEV

ARID5B

81

Q14865
PDSEHGLSPDSENFD

APC

2086

P25054
PLPDSEEEGHDNQEA

NCOA2

206

Q15596
SPGQDAEDEEATPHE

USP42

636

Q9H9J4
GEHSQNGEEEPETEP

RILPL1

256

Q5EBL4
GEAHPESEDVDAQEA

RP1L1

2076

Q8IWN7
DQQFPDGDDEFDSPH

STX11

16

O75558
DDGNTTPRNHGVDDD

SPARCL1

326

Q14515
GFARRPDPDSDEDED

RBM17

146

Q96I25
PHEAERPDGSEDAED

TNPO2

346

O14787
QDEGAEEPHEAGEQL

UBE2O

446

Q9C0C9
GLQGDSAHEPENPED

REM2

136

Q8IYK8
TGDDEAERGHQPPAS

USP31

1266

Q70CQ4
EDGEEEAAPGPRQAH

TTYH3

421

Q9C0H2
DIPEGRSHADQDSNP

TEX38

106

Q6PEX7
EEDRAQTPHEDGGPQ

TRIM56

436

Q9BRZ2