Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF4599

SPATA31A3 SPATA31C2 SPATA31A6 SPATA31C1

1.75e-0712834PF15371
DomainDUF4599

SPATA31A3 SPATA31C2 SPATA31A6 SPATA31C1

1.75e-0712834IPR027970
DomainIRF1/IRF2

IRF1 IRF2

1.95e-052832IPR017431
DomainIRF

IRF1 IRF2

6.88e-049832SM00348
DomainInterferon_reg_fact_DNA-bd_dom

IRF1 IRF2

6.88e-049832IPR001346
DomainIRF

IRF1 IRF2

6.88e-049832PF00605
DomainIRF_1

IRF1 IRF2

6.88e-049832PS00601
DomainInterferon_reg_fac_CS

IRF1 IRF2

6.88e-049832IPR019817
DomainIRF_2

IRF1 IRF2

6.88e-049832PS51507
DomainCation_ATPase_N

ATP13A2 ATP2A3

2.85e-0318832SM00831
DomainATPase_P-typ_cation-transptr_N

ATP13A2 ATP2A3

3.18e-0319832IPR004014
DomainCH

CAMSAP3 MACF1 IQGAP3

3.74e-0370833PF00307
DomainCH

CAMSAP3 MACF1 IQGAP3

4.21e-0373833PS50021
DomainCH-domain

CAMSAP3 MACF1 IQGAP3

4.54e-0375833IPR001715
DomainAcetyltransf_1

SAT1 NAA40

4.65e-0323832PF00583
DomainGNAT

SAT1 NAA40

5.48e-0325832PS51186
DomainGNAT_dom

SAT1 NAA40

5.48e-0325832IPR000182
Pubmed

Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages.

TLR4 IRF1 IRF2

5.63e-0848537822029
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A3 SPATA31A6 SPATA31C1

2.80e-07685320850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A3 SPATA31A6 SPATA31C1

2.80e-07685325930072
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

PRMT5 POLRMT MACF1 DIDO1 ASXL2 CDT1 CHEK1 CABIN1

4.62e-0728185824163370
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

LAMB4 PARP4 URB1 RPN1 DISC1 PRMT5 CAMSAP3 TSPYL6 ALB ACVR1B FBXO34

1.82e-06736851129676528
Pubmed

Gene expression profiling identifies eleven DNA repair genes down-regulated during mouse neural crest cell migration.

ERCC6L CDT1 CHEK1

2.29e-061185321425081
Pubmed

Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts.

RBBP8 DIDO1 RBM38

5.03e-061485326201719
Pubmed

HIRA contributes to zygote formation in mice and is implicated in human 1PN zygote phenotype.

CABIN1 HIRA

5.90e-06285233835048
Pubmed

Transcriptome sequencing wide functional analysis of human mesenchymal stem cells in response to TLR4 ligand.

TLR4 IRF1

5.90e-06285227444640
Pubmed

Assignment of the gene for a ubiquitin fusion degradation protein (Ufd1l) to mouse chromosome 16B1-B4, syntenic with the Tuple1 gene.

UFD1 HIRA

5.90e-0628529284932
Pubmed

Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells.

IRF1 IRF2

5.90e-06285210934221
Pubmed

TLR4 abrogates the Th1 immune response through IRF1 and IFN-β to prevent immunopathology during L. infantum infection.

TLR4 IRF1

5.90e-06285232210480
Pubmed

Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R.

CDT1 CHEK1

5.90e-06285220609246
Pubmed

Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif.

RBBP8 CTBP1

5.90e-0628529535825
Pubmed

Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon gamma-dependent cyclooxygenase 2 expression.

IRF1 IRF2

5.90e-06285210859338
Pubmed

Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system.

IRF1 IRF2

5.90e-0628527507207
Pubmed

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development.

IRF1 IRF2

5.90e-0628528402903
Pubmed

Repression of IFN-gamma induction of class II transactivator: a role for PRDM1/Blimp-1 in regulation of cytokine signaling.

IRF1 IRF2

5.90e-06285216982896
Pubmed

The CAMSAP3-ACF7 Complex Couples Noncentrosomal Microtubules with Actin Filaments to Coordinate Their Dynamics.

CAMSAP3 MACF1

5.90e-06285227693509
Pubmed

Mesenchymal stem cells (MSCs) from the mouse bone marrow show differential expression of interferon regulatory factors IRF-1 and IRF-2.

IRF1 IRF2

5.90e-06285238194130
Pubmed

A genome-wide screen identifies IRF2 as a key regulator of caspase-4 in human cells.

IRF1 IRF2

5.90e-06285231353801
Pubmed

Hepatocyte-specific METTL3 ablation by Alb-iCre mice (GPT), but not by Alb-Cre mice (JAX), resulted in acute liver failure (ALF) and postnatal lethality.

METTL3 ALB

5.90e-06285238656880
Pubmed

An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids.

ROCK1 DIAPH3

5.90e-06285224587343
Pubmed

Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.

ST7 PRMT5

5.90e-06285224453002
Pubmed

Differential dysregulation of nitric oxide production in macrophages with targeted disruptions in IFN regulatory factor-1 and -2 genes.

IRF1 IRF2

5.90e-0628528617930
Pubmed

Interferon regulatory factor-1 promoter polymorphism and the outcome of hepatitis C virus infection.

IRF1 MX1

5.90e-06285216894313
Pubmed

A Protumorigenic mDia2-MIRO1 Axis Controls Mitochondrial Positioning and Function in Cancer-Associated Fibroblasts.

DIAPH3 RHOT1

5.90e-06285235997559
Pubmed

Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7.

CAMSAP3 MACF1

5.90e-06285227802168
Pubmed

Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes.

IRF1 IRF2

5.90e-0628522475256
Pubmed

m6A-related bioinformatics analysis and functional characterization reveals that METTL3-mediated NPC1L1 mRNA hypermethylation facilitates progression of atherosclerosis via inactivation of the MAPK pathway.

METTL3 NPC1L1

5.90e-06285236583755
Pubmed

The role of interferon regulatory factors in the interferon system and cell growth control.

IRF1 IRF2

5.90e-0628529865486
Pubmed

Interferon regulatory factor 1 inactivation in human cancer.

IRF1 IRF2

5.90e-06285229599126
Pubmed

Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide-induced Inflammation in Corneal Epithelial Cells by Activating Toll-Like Receptor 4 (TLR4)-Mediated Signaling.

TLR4 ROCK1

5.90e-06285229804125
Pubmed

The roles of interferon regulatory factors 1 and 2 in the progression of human pancreatic cancer.

IRF1 IRF2

5.90e-06285224632547
Pubmed

A diverse range of gene products are effectors of the type I interferon antiviral response.

IRF1 IRF2 MX1

9.35e-061785321478870
Pubmed

Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit.

CABIN1 HIRA

1.77e-05385230082790
Pubmed

IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice.

IRF1 IRF2

1.77e-05385210415056
Pubmed

Interferon regulatory factors: the next generation.

IRF1 IRF2

1.77e-05385210524230
Pubmed

Interaction of checkpoint kinase 1 and the X-linked inhibitor of apoptosis during mitosis.

BIRC8 CHEK1

1.77e-05385214759516
Pubmed

Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells.

IRF1 IRF2

1.77e-05385215226432
Pubmed

B lymphocyte-induced maturation protein (Blimp)-1, IFN regulatory factor (IRF)-1, and IRF-2 can bind to the same regulatory sites.

IRF1 IRF2

1.77e-05385215494505
Pubmed

Functional domain analysis of interferon consensus sequence binding protein (ICSBP) and its association with interferon regulatory factors.

IRF1 IRF2

1.77e-0538527768900
Pubmed

RNA interference of interferon regulatory factor-1 gene expression in THP-1 cell line leads to Toll-like receptor-4 overexpression/activation as well as up-modulation of annexin-II.

TLR4 IRF1

1.77e-05385218084608
Pubmed

Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes.

PDGFB TLR4

1.77e-05385225327457
Pubmed

TRIM14 expression is regulated by IRF-1 and IRF-2.

IRF1 IRF2

1.77e-05385231150153
Pubmed

Analysis of MxA, IL-4, and IRF-1 genes in Filipino patients with subacute sclerosing panencephalitis.

IRF1 MX1

1.77e-05385217177148
Pubmed

METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1.

METTL3 PRMT5

1.77e-05385234476262
Pubmed

The role of the interferon regulatory factors, IRF-1 and IRF-2, in LPS-induced cyclooxygenase-2 (COX-2) expression in vivo and in vitro.

IRF1 IRF2

1.77e-05385212537697
Pubmed

Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage.

RBBP8 CTBP1

1.77e-05385210196224
Pubmed

The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2.

IRF1 IRF2

1.77e-0538527650042
Pubmed

Transcriptional regulation of the 230-kDa bullous pemphigoid antigen gene expression by interferon regulatory factor 1 and interferon regulatory factor 2 in normal human epidermal keratinocytes.

IRF1 IRF2

1.77e-05385215560761
Pubmed

DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking.

DISC1 RHOT1

1.77e-05385224092329
Pubmed

Interferon regulatory factor 1 (IRF-1) and IRF-2 regulate PD-L1 expression in hepatocellular carcinoma (HCC) cells.

IRF1 IRF2

1.77e-05385232377817
Pubmed

TLR4/IL-6/IRF1 signaling regulates androgen receptor expression: A potential therapeutic target to overcome taxol resistance in ovarian cancer.

TLR4 IRF1

1.77e-05385233556340
Pubmed

The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling.

RBBP8 CTBP1

1.77e-05385211313276
Pubmed

Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.

AGXT2 ALB

1.77e-05385227752141
Pubmed

Myosin phosphatase and RhoA-activated kinase modulate arginine methylation by the regulation of protein arginine methyltransferase 5 in hepatocellular carcinoma cells.

PRMT5 ROCK1

1.77e-05385228074910
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A3 SPATA31A6 SPATA31C1

2.75e-052485332212159
Pubmed

An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes.

IRF1 IRF2

3.53e-0548522111015
Pubmed

CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling.

TLR4 CHEK1

3.53e-05485227685627
Pubmed

Coactivator p300 acetylates the interferon regulatory factor-2 in U937 cells following phorbol ester treatment.

IRF1 IRF2

3.53e-05485211304541
Pubmed

Identification of an ubinuclein 1 region required for stability and function of the human HIRA/UBN1/CABIN1/ASF1a histone H3.3 chaperone complex.

CABIN1 HIRA

3.53e-05485222401310
Pubmed

Amino acid deprivation links BLIMP-1 to the immunomodulatory enzyme indoleamine 2,3-dioxygenase.

IRF1 IRF2

3.53e-05485219828629
Pubmed

Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages.

TLR4 CTBP1

3.53e-05485223853092
Pubmed

Genetic Susceptibility to Life-threatening Respiratory Syncytial Virus Infection in Previously Healthy Infants.

TLR4 MX1

3.53e-05485232740454
Pubmed

Apolipoprotein L1 is transcriptionally regulated by SP1, IRF1 and IRF2 in hepatoma cells.

IRF1 IRF2

3.53e-05485232671843
Pubmed

IFN regulatory factor-2 cooperates with STAT1 to regulate transporter associated with antigen processing-1 promoter activity.

IRF1 IRF2

3.53e-05485215778351
Pubmed

Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy.

IRF1 IRF2

3.53e-05485212960317
Pubmed

UBE3A regulates the transcription of IRF, an antiviral immunity.

IRF1 IRF2

3.53e-05485230690483
Pubmed

IFN-gamma represses IL-4 expression via IRF-1 and IRF-2.

IRF1 IRF2

3.53e-05485212479817
Pubmed

Possible involvement of the transcription factor ISGF3 gamma in virus-induced expression of the IFN-beta gene.

IRF1 IRF2

3.53e-0548527843405
Pubmed

Human CABIN1 is a functional member of the human HIRA/UBN1/ASF1a histone H3.3 chaperone complex.

CABIN1 HIRA

3.53e-05485221807893
Pubmed

Interferon regulatory factor 1-Rab27a regulated extracellular vesicles promote liver ischemia/reperfusion injury.

TLR4 IRF1

3.53e-05485229059701
Pubmed

Histone chaperones cooperate to mediate Mef2-targeted transcriptional regulation during skeletal myogenesis.

CABIN1 HIRA

3.53e-05485221414300
Pubmed

The H3.3 chaperone Hira complex orchestrates oocyte developmental competence.

CABIN1 HIRA

3.53e-05485235112132
Pubmed

The histone acetylase PCAF is a phorbol-ester-inducible coactivator of the IRF family that confers enhanced interferon responsiveness.

IRF1 IRF2

3.53e-05485210022868
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

URB1 SCCPDH RPN1 ST7 PRMT5 UFD1 POLRMT IRF2 CTBP1 CABIN1 NCAPH MX1 HIRA

4.58e-051440851330833792
Pubmed

Ubc9-mediated sumoylation leads to transcriptional repression of IRF-1.

IRF1 IRF2

5.87e-05585218955028
Pubmed

Identification of novel co-repressor molecules for Interferon Regulatory Factor-2.

IRF1 IRF2

5.87e-05585212799427
Pubmed

Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor.

RBBP8 CTBP1

5.87e-05585210764811
Pubmed

Interferon regulatory transcription factors are constitutively expressed and spatially regulated in the mouse lens.

IRF1 IRF2

5.87e-05585210364426
Pubmed

Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth.

IRF1 IRF2

5.87e-0558529865487
Pubmed

RanBP1, a velocardiofacial/DiGeorge syndrome candidate gene, is expressed at sites of mesenchymal/epithelial induction.

UFD1 HIRA

5.87e-05585211804793
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

VANGL2 KIDINS220 FBXO3 RPN1 MACF1 DIDO1 CTBP1 NAA40 ALB ZMYM3 HIRA

6.54e-051082851138697112
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RBBP8 CAMSAP3 POLRMT CTBP1 CHEK1 DIAPH3 ZMYM3

7.60e-0541885734709266
Pubmed

Expression of the Bcl-2 protein BAD promotes prostate cancer growth.

TLR4 IRF1 CHEK1

7.98e-053485319593445
Pubmed

Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription.

IRF1 IRF2

8.80e-05685222042864
Pubmed

Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis.

IRF1 IRF2

8.80e-05685211859135
Pubmed

RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes.

RBBP8 CTBP1

8.80e-05685216287852
Pubmed

HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections.

IRF1 IRF2

8.80e-05685228970238
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SEC24D KIDINS220 SMC6 CTBP1 ALB ACVR1B NCAPH PKHD1L1 ARAP2

1.20e-0477785935844135
Pubmed

High expression of Endogenous Retroviruses from intrauterine life to adulthood in two mouse models of Autism Spectrum Disorders.

DISC1 TLR4

1.23e-04785229330412
Pubmed

EXD2 promotes homologous recombination by facilitating DNA end resection.

RBBP8 CTBP1

1.23e-04785226807646
Pubmed

HIRA and Daxx constitute two independent histone H3.3-containing predeposition complexes.

CABIN1 HIRA

1.23e-04785221047901
Pubmed

Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure.

VANGL2 ROCK1

1.23e-04785225596276
Pubmed

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.

ST7 PRMT5

1.23e-04785215485929
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

URB1 KIDINS220 RPN1 NPC1L1 IQGAP3

1.42e-0420285524639526
Pubmed

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.

ALB CDT1 CHEK1

1.62e-044385330733279
Pubmed

Ikaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repression.

RBBP8 CTBP1

1.64e-04885211959865
Pubmed

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.

CTBP1 CHEK1

1.64e-04885225086746
InteractionHECW2 interactions

PRMT5 POLRMT MACF1 DIDO1 ASXL2 CDT1 CHEK1 ARRDC3 CABIN1

7.07e-06322839int:HECW2
ToppCellBiopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ERCC6L CDT1 CHEK1 DIAPH3 PSAPL1 NCAPH IQGAP3

1.10e-071998574fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell(1)_T_cell-(18)_cycling_gd_T|(1)_T_cell / shred on Cell_type and subtype

SCCPDH PRSS57 CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

1.10e-071998579369d0e4efe809e3e8757294ebebba5a47b30528
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

8.79e-07169856a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

8.79e-07169856195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TFAP2E RBBP8 CDT1 CHEK1 NCAPH PKHD1L1

1.08e-0617585689bf89466191da14896ed8928027f5b911436c22
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG4B ERCC6L DIAPH3 NCAPH IQGAP3 RBM38

1.08e-06175856f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

1.44e-061848566b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

1.44e-06184856e90622b82fa7f16a1faaf7a4724c958f2d83341d
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

1.69e-06189856fd8834d1feb7f63911c5fa51efb1f679a8baddeb
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

LAMB4 ERCC6L CDT1 CHEK1 DIAPH3 NCAPH

1.79e-06191856210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

1.96e-06194856f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH PKHD1L1

1.96e-061948565a519538327029ad2b880ef9647e2ac6ab3961a4
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

1.96e-061948564d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

SCCPDH CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

1.96e-06194856a12b64945e10f00aa983678a02586c59badc1570
ToppCellDividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.02e-0619585679ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCellDividing_cells-Dividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.02e-0619585619829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCell(1)_T_cells-(1)_T_cells_Dividing|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

RBBP8 CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.02e-06195856cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH HYDIN

2.02e-06195856957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-061968566d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCellBAL-Control-Myeloid-Myeloid|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-06196856bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCellcycling_basal_cell|World / shred by cell class for nasal brushing

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-06196856aa7bac70a2fe4a3cb28d89fa1a87c68c2ead1349
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-061968561964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-061968563dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-0619685673f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellcontrol-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ERCC6L RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

2.08e-06196856886f7c865b086d6ebb4a1746865c30af6bbed345
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-061968564f649e3bfd21f21682678828673843a7d51c4ff2
ToppCellBAL-Control-Myeloid-Myeloid|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-06196856799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.08e-061968560c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCellControl-T/NK_proliferative|Control / Disease condition and Cell class

ERCC6L RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

2.08e-061968567b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.14e-0619785684ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellControl-Myeloid-proliferating_Myeloid_cells|Control / Disease group,lineage and cell class （2021.01.30）

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.14e-06197856ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCellHealthy_Control-Lymphoid-T-Proliferating_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.14e-061978563ce3dcbbe0edeb5a6fb5596dd6c2b4d6c1d5159d
ToppCell(0)_NK_cells-(0)_NK_Dividing|(0)_NK_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

ERCC6L RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

2.21e-06198856d9cdbc7d420472cb1ffb36ad9c8e53a61b7dbdeb
ToppCellmedial-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.21e-0619885664a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCellmedial-Hematologic-Proliferating_Macrophage-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.21e-06198856fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCellmedial-Hematologic-Proliferating_Macrophage|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.21e-06198856da6963184c32761c896a9b91a5321ad84b583736
ToppCellproximal-Epithelial-Proliferating_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.27e-06199856521ff4ae3437c8ba477a0a42b9da195af976c3ff
ToppCellVE-cycling|VE / Condition, Cell_class and T cell subcluster

ERCC6L RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

2.27e-0619985647c47ebc318a0b98841ca2656837bbd068899559
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating-Cycling_Progenitors|6_mon / Sample Type, Dataset, Time_group, and Cell type.

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.27e-06199856a99516a5760f49a69b0fe45a9b2316e393252966
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TFAP2E ERCC6L CDT1 CHEK1 NCAPH DNAH1

2.27e-06199856c6d59ed26eadd3c41acfe1b4d929270e00ea3e95
ToppCellproximal-Epithelial-Proliferating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.27e-06199856e8549b2c4152cb23548351d9cee27c3805892cd8
ToppCellproximal-3-Epithelial-Proliferating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.27e-061998562263bb73d9c5693b44d91d2548305efc1b6e4079
ToppCellVE-cycling-|VE / Condition, Cell_class and T cell subcluster

ERCC6L RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

2.27e-06199856c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma|TCGA-Bladder / Sample_Type by Project: Shred V9

ALKBH4 RPN1 NAA40 CDT1 NCAPH IQGAP3

2.27e-061998568ee3dbc0a92de5f3865e5484970ae2aab7d1a956
ToppCellMild-T/NK_proliferative|Mild / Disease group and Cell class

ERCC6L RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

2.27e-0619985664a5c91243ee999ea21ffddd450d3e5fdbf6470b
ToppCellTCGA-Bladder-Primary_Tumor|TCGA-Bladder / Sample_Type by Project: Shred V9

ALKBH4 RPN1 NAA40 CDT1 NCAPH IQGAP3

2.27e-06199856c403e28def2e14f5931cd73b4fb9a4078c0439f8
ToppCelldistal-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-062008560cd3b01fb7f579e5abf000adb8ec8adc7cd779c4
ToppCellBiopsy_IPF-Epithelial-Proliferating_Epithelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-0620085663c5402f050fdb12abab3c8b7f33d4914ae26b9b
ToppCellNS-moderate-d_07-13-Lymphoid-NKT-proliferating|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-0620085687e293c0882e2754756a2210a6c04723dc89f81b
ToppCellPSB-critical-LOC-Lymphoid-Treg|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-062008563e3de496508efb2f95e5e8684f97687381e96493
ToppCellLAM-Myeloid-pMacrophage|LAM / Condition, Lineage and Cell class

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-062008567e233d037165c9d3607604aaaf0f368e266567d3
ToppCellSepsis-URO-Lymphocyte-T/NK-T/NK_proliferative|URO / Disease, condition lineage and cell class

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-06200856f277db6cc288a52a5426120c1067608700ee8ccc
ToppCellNS-critical-d_07-13-Lymphoid-NKT-proliferating|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-062008567f5cd05bb1b9a83baceddb7d7f0a9ec9781cda29
ToppCellMS-IIF-Lymphocyte-T/NK-T/NK_proliferative|IIF / Disease, condition lineage and cell class

ERCC6L RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

2.34e-06200856c7c1806a1054b2b034a26a18aac93fc3bec4dbc8
ToppCellBiopsy_Other_PF-Immune-Proliferating_Macrophages|Biopsy_Other_PF / Sample group, Lineage and Cell type

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-0620085661473e8613f39a92002d5b631e6bd563735566e4
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG4B CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-06200856af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellcritical-Lymphoid-NKT-proliferating|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.34e-06200856d698458b90bf8256fe664618ef27620aa910b02a
ToppCell(18)_cycling_gd_T|World / shred on Cell_type and subtype

PRSS57 CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

2.55e-062038567d58929058c4769226a29febee1fd8ba64bc9f1a
ToppCellClub_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

VANGL2 PLEKHG4B NR2E3 TFAP2E IQGAP3

3.43e-061208557f85208f0455f3e634f8e7e81beea60b4ef1d2a5
ToppCellCOVID-19-APC-like-Alveolar_macrophages|COVID-19 / group, cell type (main and fine annotations)

TFAP2E TLR4 RIC8A ACMSD ADAM28

1.23e-05156855735ade77cfa16b9386a0c7ec2bd14bd2e78a51ad
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METTL3 ERCC6L CDT1 CHEK1 DIAPH3

1.31e-05158855ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PARP4 PERM1 DIAPH3 ACMSD HYDIN

1.57e-051648551cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L CDT1 DIAPH3 NCAPH IQGAP3

1.81e-05169855e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB PKHD1L1 ADAM28 HYDIN DNAH1

1.81e-0516985512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS57 ERCC6L ALB ACVR1B IQGAP3

1.97e-05172855c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRSS57 RBBP8 CDT1 DIAPH3 NCAPH

2.14e-051758550b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC6L CHEK1 DIAPH3 IQGAP3 HIRA

2.14e-0517585573f25bd54309aed1480ddc44bdab518b17e71f92
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

PRSS57 CDT1 DIAPH3 NCAPH IQGAP3

2.14e-0517585574800a10f5ff25d5414fbccb0668f92ff077d1cc
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L CDT1 DIAPH3 NCAPH IQGAP3

2.26e-05177855f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RBBP8 ST7 CDT1 CHEK1 ADAM28

2.26e-05177855cbedac0bddb8fc330a464815c905928c553b0fc0
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RBBP8 ST7 CDT1 CHEK1 ADAM28

2.33e-0517885504bfecf5ea5d85c843e48d08718b5d69e7bf834e
ToppCellDividing_Macrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

AGXT2 CDT1 DIAPH3 NCAPH IQGAP3

2.33e-051788551893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TLR4 CDT1 CHEK1 NCAPH IQGAP3

2.39e-05179855e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L CDT1 DIAPH3 NCAPH IQGAP3

2.45e-05180855334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH

2.52e-0518185573b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRSS57 ERCC6L CHEK1 DIAPH3 NCAPH

2.52e-05181855cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRSS57 ERCC6L CHEK1 DIAPH3 NCAPH

2.52e-0518185574311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T|Liver / Manually curated celltypes from each tissue

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH

2.59e-0518285581557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCellCV-Severe-3|CV / Virus stimulation, Condition and Cluster

PRSS57 OXCT2 CDT1 CHEK1 CCDC7

2.73e-051848551c9bda00bb6efd98f68781ca06655bf6c4282f27
ToppCellIIF-Lymphocyte-T_NK-T_NK_proliferative|IIF / Disease, Lineage and Cell Type

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH

2.73e-05184855ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH

2.80e-051858550ae9c646679c69a553eda670aef0e0495feb0286
ToppCell10x5'-Liver-Lymphocytic_NK-Cycling_NK|Liver / Manually curated celltypes from each tissue

RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

3.02e-051888555eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

3.02e-05188855723348a1836a074e068320cb736ce6a953e0038f
ToppCell3'_v3-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

3.02e-051888550e8ac42c439f30a05e015210e1d5c2dcb9d9d471
ToppCellNS-critical-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L CHEK1 DIAPH3 NCAPH IQGAP3

3.10e-05189855d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCellBac-SEP-Lymphocyte-B-Plasmablast|Bac-SEP / Disease, Lineage and Cell Type

CDT1 CHEK1 DIAPH3 NCAPH PKHD1L1

3.10e-051898556339b6d1056e07cefb0e1b2a0e479913c5783c8a
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

ERCC6L CDT1 CHEK1 NCAPH IQGAP3

3.10e-05189855946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

3.18e-05190855005967c540418b85311308072a07c684f4296aef
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-Cycling_NK|lymph-node_spleen / Manually curated celltypes from each tissue

CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

3.18e-05190855451eaceb0cb0ec6cfcae00253c0e5c92a168c2f3
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC6L CHEK1 DIAPH3 NCAPH IQGAP3

3.26e-0519185515dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCellDividing_Macrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ERCC6L CDT1 DIAPH3 NCAPH IQGAP3

3.26e-051918553e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

3.26e-05191855d6e158f16a183c9203c057192342e9b83e79bc89
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDT1 CHEK1 DIAPH3 NCAPH IQGAP3

3.26e-051918557cb5c6f2cf27f3503d1b313e402a7410dfe6473e
ToppCellMild-T/NK_proliferative|World / Disease group and Cell class

RBBP8 CDT1 CHEK1 DIAPH3 NCAPH

3.26e-051918559dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC6L CHEK1 DIAPH3 NCAPH IQGAP3

3.26e-0519185545c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RBBP8 CDT1 DIAPH3 NCAPH IQGAP3

3.26e-0519185550854384fdaa0efa2e3227659d544ed09ac102f2
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic-lymphocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH

3.26e-0519185556b45259dfc38bd5ea43b0e3adf47e7e2c043a5d
ToppCell(3)_Macrophage_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SCCPDH CDT1 DIAPH3 NCAPH IQGAP3

3.26e-05191855b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6L CDT1 CHEK1 DIAPH3 NCAPH

3.34e-05192855e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Control / Condition, Lineage and Cell class

ERCC6L CDT1 DIAPH3 NCAPH IQGAP3

3.42e-0519385533d409d6ed1c606337248587ad997ac5f67f081d
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; PC3; HT_HG-U133A

URB1 PDGFB ZNF862 ACVR1B CABIN1 MX1 HIRA

7.29e-062008175750_DN
DrugDenatonium benzoate [3734-33-6]; Up 200; 9uM; MCF7; HT_HG-U133A

SEC24D NR2E3 URB1 RNF144A NAA40 ATP2A3 CSPP1

7.29e-062008176502_UP
Diseaserenal overload-type gout

SPATA31C2 SPATA31C1

1.11e-046812EFO_0021525
Diseaseeosinophil cationic protein measurement

SPATA31C2 SPATA31C1

2.06e-048812EFO_0010913
DiseaseLeydig cell tumor (is_marker_for)

PDGFB PRMT5

2.06e-048812DOID:2696 (is_marker_for)
Disease22q11 partial monosomy syndrome

UFD1 HIRA

2.65e-049812C3266101
Diseaselongitudinal alcohol consumption measurement

SPATA31C2 SPATA31C1

2.65e-049812EFO_0007645
DiseaseAsymmetric crying face association

UFD1 HIRA

3.30e-0410812C0431406
Disease22q11 Deletion Syndrome

UFD1 HIRA

3.30e-0410812C2936346
DiseaseFibrosis

PDGFB TLR4 ALB

3.56e-0450813C0016059
DiseaseCirrhosis

PDGFB TLR4 ALB

3.56e-0450813C1623038
DiseaseLiver carcinoma

TGM3 PDGFB TLR4 IRF2 CDT1 NCAPH IQGAP3

4.93e-04507817C2239176
Diseaseegg allergy measurement, parental genotype effect measurement

SPATA31C2 SPATA31C1

5.69e-0413812EFO_0005939, EFO_0007018
DiseaseDiGeorge Syndrome

UFD1 HIRA

8.71e-0416812C0012236
Diseaseamygdala volume change measurement

SPATA31C2 SPATA31C1

8.71e-0416812EFO_0021490
DiseaseCONOTRUNCAL ANOMALY FACE SYNDROME

UFD1 HIRA

8.71e-0416812C0795907
DiseaseShprintzen syndrome

UFD1 HIRA

8.71e-0416812C0220704
Diseasesinusitis (is_marker_for)

PDGFB TLR4

1.11e-0318812DOID:0050127 (is_marker_for)
DiseaseLung Injury

TLR4 ALB

1.51e-0321812C0273115
DiseaseChronic Lung Injury

TLR4 ALB

1.51e-0321812C2350344
DiseaseSeckel syndrome

RBBP8 CDT1

1.66e-0322812C0265202
Diseasehematocrit

NR2E3 RNF144A ASXL2 CDT1 ACVR1B ACMSD HYDIN RBM38 SLC4A2

1.80e-031011819EFO_0004348
Diseasephysical activity

CTCFL TLR4 ARAP2

1.85e-0388813EFO_0003940
Diseasenecrotizing enterocolitis

RNF144A ADAM28

2.50e-0327812EFO_0003928
Diseasealpha fetoprotein measurement

RBBP8 SMC6 ACMSD

2.66e-03100813EFO_0010583

Protein segments in the cluster

PeptideGeneStartEntry
IAKDMEDSVPLDCSR

VANGL2

91

Q9ULK5
SMCITKPEVDFAVEV

AGXT2

486

Q9BYV1
MAAAAAETPEVLREC

ALKBH4

1

Q9NXW9
VKRISEARECENMFP

FAM227A

391

F5H4B4
REMKCLDANEAEPVF

SLC4A2

1211

P04920
EAKRMPCAEDYLSVV

ALB

466

P02768
RDCTVEMPILKDVAT

CTBP1

36

Q13363
EMPILKDVATVAFCD

CTBP1

41

Q13363
EMFPVACRETTARVK

CTCFL

631

Q8NI51
ADMPAEEREKKLASC

RBBP8

821

Q99708
MDKENRPEAVKSCEA

CCDC7

226

Q96M83
AVKIVDMKRAVDCPE

CHEK1

36

O14757
RVDDTLIPCKANDTM

ADAM28

546

Q9UKQ2
SDPSIEEMRKVVCDQ

ACVR1B

436

P36896
PVRVLDMVAKLESEC

FBXO34

276

Q9NWN3
VSERKPALSMEVACA

CDT1

466

Q9H211
APELAVKEMERCVKE

ACMSD

121

Q8TDX5
LCAAVVKPDVLETMA

ARAP2

816

Q8WZ64
IKPDIMAVSTACEEI

DIAPH3

816

Q9NSV4
KLVTDCVAAMNPDAV

BPNT1

201

O95861
RLEEVCLKDPMSVAD

CAMSAP3

251

Q9P1Y5
PAKEAGEREAAASCM

DISC1

831

Q9NRI5
FAEIENCSSRMVVPK

ARRDC3

211

Q96B67
PRKEDMELDDCSKFV

ATP2A3

571

Q93084
MKRTKCADIDVETPD

ASXL2

261

Q76L83
ICKEFADLMAQDRSP

TFAP2E

351

Q6VUC0
TMADRAAAERACKDP

RBM38

81

Q9H0Z9
RALAVDPTEFACMKA

NR2E3

311

Q9Y5X4
FRCAMNSLPDIEEVK

IRF1

81

P10914
FRCAMNSLPDIEEVK

IRF2

81

P14316
QDPIIARMSICSEDK

KIDINS220

1636

Q9ULH0
TEKVLSICPKDMRAD

KCNH5

521

Q8NCM2
RIEMSKDALPEKACQ

FBXO3

311

Q9UK99
PAMIAECKTRTEVFE

PDGFB

91

P01127
MDSRIPCLIVAAKSD

RHOT1

516

Q8IXI2
SPEICKMADNLDEFI

CSPP1

31

Q1MSJ5
KESEACMLVFQPDLD

PARP4

851

Q9UKK3
EAAEMDCLQDPAKLS

OC90

126

Q02509
RVAADTVKELMCPEA

IQGAP3

391

Q86VI3
LEERAAMDAVCAKVD

NAA40

16

Q86UY6
MALDEFLVKNDPCRA

MACF1

7176

Q9UPN3
KEECMKASDADRPCR

METTL3

281

Q86U44
AAFKMEEDDAPIKRC

RNF144A

171

P50876
PDLSSMTEEEKIVCA

PIPSL

761

A2A3N6
RAEEAVAAVMVASCP

NPC1L1

1306

Q9UHC9
FKDMPACQEVALDIR

DNAH1

1071

Q9P2D7
FARMAPEQKTELVCE

ATP13A2

851

Q9NQ11
VDIFEVEPSKMCIAS

HYDIN

3411

Q4G0P3
VIDCSMAVQEEAKEP

CABIN1

826

Q9Y6J0
AVDRCPMCSAVIDFK

BIRC8

216

Q96P09
EAKVTVDDLPNRMCA

DIDO1

1436

Q9BTC0
ACREKDRDPEAQFEM

PRMT5

486

O14744
ANMEDKRETLPVCEA

LAMB4

1201

A4D0S4
TAEKEAMCLSAPALA

HIRA

666

P54198
MELASRVCVVSVEKP

POLRMT

406

O00411
EALPDVSRAKSDMAV

PERM1

286

Q5SV97
DVDAICEMPSLSRKN

ERCC6L

351

Q2NKX8
DCTVLPEMKEIVSRD

PRR14L

1276

Q5THK1
LERVCSVMPASITKE

PSAPL1

321

Q6NUJ1
SELRAMAKAAREECP

TIGAR

101

Q9NQ88
PRKLCLMEEAVSEFE

SPATA31C2

846

B4DYI2
ICDIANPASLDEMAK

SCCPDH

76

Q8NBX0
PRKLCLMEEVVSEFE

SPATA31A6

996

Q5VVP1
AVAEAACPGITDKMV

STK26

386

Q9P289
MEAKVRVLDPDVCNS

PRSS57

176

Q6UWY2
DPAAEARMKVACITE

RPN1

466

P04843
MAKFVIRPATAADCS

SAT1

1

P21673
DPRKLCLMEEAVSEF

SPATA31C1

851

P0DKV0
CKSIFMRVEDELEIP

ST7

561

Q9NRC1
PESADMDVVLESLKC

RIC8A

106

Q9NPQ8
LTHVRMVCEAADDAP

URB1

2236

O60287
NVPMCKAADVTAVEV

OXCT2

231

Q9BYC2
DVKSTMLPAAVRCSE

SEC24D

896

O94855
SDNMIRITAVCKVPD

TGM3

566

Q08188
NVSEADRKCEIDPMF

NCAPH

231

Q15003
DRKCEIDPMFQKTAA

NCAPH

236

Q15003
RKLCLMEEVVSEFEP

SPATA31A3

1001

Q5VYP0
AVISDRAPKCAVMSD

PLEKHG4B

1141

Q96PX9
RAPKCAVMSDRVPDS

PLEKHG4B

1146

Q96PX9
ARAPECMALKADVVA

SMC6

341

Q96SB8
RPDISKVNPSDCVDM

PKHD1L1

3661

Q86WI1
ANEGECRKDVEMEPV

ROCK1

1201

Q13464
LPSREAAEVLKDCIM

ZNF862

1136

O60290
AAEVLKDCIMEPPER

ZNF862

1141

O60290
PDKAVSIIECDMNVD

UFD1

176

Q92890
KAEDVKPEECAMFSA

TSPYL6

146

Q8N831
LVEVERMECATPSDK

TLR4

601

O00206
PMRIKEDILACSAAE

ZMYM3

1096

Q14202
VEGKAEPAMRKDDVC

TXNRD3NB

111

Q6F5E7
MVVSEVDIAKADPAA

MX1

1

P20591