Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
PathwayWP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME

ESCO1 PPP2R5A PPP2R5E SGO2 ESPL1

6.13e-06341105M42555
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

LARGE2 CYP17A1 SEC31A PFKL TTC3 ARFIP1 MADD RPS6KC1 MED24 KMT2C TAOK3 PPP2R5E RESF1 SYNJ1 ANKRD17 SYT1 MACF1 ESPL1 USP3 RAD17 BRWD1

2.18e-0810841572111544199
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CDK8 ERCC6 ATAD5 APP PRDM5 FANCD2 JAK1 PPP2R5A PPP2R5E RESF1 GFOD1 TBK1 ZFP1 ANKRD17 MACF1 ZFHX3 SCRIB TAF11 IQCM TBX2 BRWD1

3.58e-0811161572131753913
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SYNE1 SEC31A CMYA5 KMT2E TTC3 MAP3K5 PPP2R5E XIRP2 SUPT6H TBK1 MACF1 RABGEF1 MED13 PLCE1

6.70e-084971571423414517
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SGIP1 SYNE1 RAPGEF4 NCAM1 SEC31A TTC3 MAP3K5 NEFM MDN1 SYNJ1 TBK1 MFN2 ANKRD17 SYT1 MACF1 RABGEF1 CTNNA1 SCRIB NOP2

8.15e-089631571928671696
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MAP1B NUDT21 SYNE1 GRK6 CAT PFKL APP F5 MYO5C MDN1 SACS SUPT6H TBK1 CKAP2L MACF1 HADHA CTNNA1 SCRIB NOP2

2.09e-0710241571924711643
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CDK8 SPTLC3 LRRN1 MAP1B KIZ E2F3 PFKL ARHGAP35 APP TTC3 CASC2 ESCO1 ITFG1 ARFGEF3 KMT2C ZNF532 SUPT6H TBK1 SETBP1 ANKRD17 MACF1 ZFHX3 USP3

2.63e-0714891572328611215
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATAD5 SYNE1 BAG1 BMS1 APP TTC3 ARFIP1 DNAJC2 NBAS MDN1 SACS SUPT6H MAP4K5 HGS MACF1 AKAP11 HADHA CTNNA1 SCRIB ESPL1 NOP2 PLOD2

1.01e-0614871572233957083
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CDK8 MAP1B ATAD5 DHX40 MED8 F5 MED24 TBK1 SGO2 HADHA SCRIB NOP2 USP3 MED13

1.52e-066451571425281560
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SYNE1 RAPGEF4 E2F3 SEC31A CMYA5 APP TTC3 GTF3C4 MADD JAK1 NEFM PPP2R5E SYNJ1 ZNF532 SACS MACF1 CTNNA1 SCRIB MED13 BRWD1

1.53e-0612851572035914814
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

E2F3 PARP14 TTC3 GTF3C4 JAK1 SACS MACF1 CTNNA1 SCRIB NOP2

2.98e-063321571037433992
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

DHX40 SYNE1 TRPC5 PFKL F5 RYR2 MACF1 PLOD2

3.42e-06197157820811636
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

MAP1B NCAM1 ZDBF2 CMSS1 SYT1 AKAP11

3.50e-0690157615033168
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ERCC6 ATAD5 DHX40 SYNE1 MED8 BMS1 PFKL CMSS1 APP DNAJC2 MED24 KMT2C PPP2R5E MDN1 PPP3CC SUPT6H ANKRD17 MACF1 ZFHX3 MED13 TBX2

4.17e-0614971572131527615
Pubmed

Proteomic analysis of in vivo phosphorylated synaptic proteins.

SGIP1 MAP1B NCAM1 NEFM CTNNA1

4.24e-0653157515572359
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CYLC1 MAP1B SYNE1 GRK6 MED8 BAG1 CAT TTC3 TRDN RYR2 RPS6KC1 DDX11 NEFM FRA10AC1 MDN1 SACS MACF1 HADHA NGLY1 MED13

8.51e-0614421572035575683
Pubmed

A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.

CDK8 MED8 MED24 MED13

8.69e-0629157414638676
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SYNE1 ARHGAP35 KMT2C SYNJ1 SETBP1 MACF1 AKAP11 SCRIB

9.05e-06225157812168954
Pubmed

The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator.

CDK8 MED8 MED24 MED13

1.14e-0531157423322298
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

MAP1B DHX40 BMS1 CAT PFKL ATE1 CMSS1 POLR3E SUPT6H PRIM1 TBK1 ANKRD17 HADHA SCRIB USP3 RAD17

1.38e-0510051571619615732
Pubmed

MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.

CDK8 MED8 MED24 MED13

1.67e-0534157415989967
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SGIP1 MAP1B NCAM1 ZDBF2 PFKL ATE1 ARHGAP35 APP RYR2 MADD RPS6KC1 ARFGEF3 SYNJ1 SYT1 MACF1 RABGEF1 HADHA

1.68e-0511391571736417873
Pubmed

Regulation of Chk2 phosphorylation by interaction with protein phosphatase 2A via its B' regulatory subunit.

PPP2R5A PPP2R5E CHEK2

1.93e-0512157315380617
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SYNE1 RAPGEF4 NCAM1 MAP3K5 NEFM SYNJ1 SYT1 MACF1

1.99e-05251157827507650
Pubmed

Inhibitors of catalase-amyloid interactions protect cells from beta-amyloid-induced oxidative stress and toxicity.

CAT APP

2.02e-052157220923778
Pubmed

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans.

RAPGEF4 PLCE1

2.02e-052157221478675
Pubmed

Analysis of high PSA N-CAM expression during mammalian spinal cord and peripheral nervous system development.

NCAM1 NEFM

2.02e-05215721769342
Pubmed

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe.

ERCC6 CHEK2

2.02e-05215729450932
Pubmed

Reduction of synaptojanin 1 accelerates Aβ clearance and attenuates cognitive deterioration in an Alzheimer mouse model.

APP SYNJ1

2.02e-052157224052255
Pubmed

SGIP1α functions as a selective endocytic adaptor for the internalization of synaptotagmin 1 at synapses.

SGIP1 SYT1

2.02e-052157231053155
Pubmed

Selective interaction of amyloid precursor protein with different isoforms of neural cell adhesion molecule.

NCAM1 APP

2.02e-052157221691800
Pubmed

Amyloid-beta binds catalase with high affinity and inhibits hydrogen peroxide breakdown.

CAT APP

2.02e-052157210567208
Pubmed

Thrombin-activatable fibrinolysis inhibitor antigen and TAFI activity in patients with APC resistance caused by factor V Leiden mutation.

CPB2 F5

2.02e-052157212165290
Pubmed

Dynamic regulation of pol II transcription by the mammalian Mediator complex.

MED24 MED13

2.02e-052157215896744
Pubmed

ATBF1 is a novel amyloid-β protein precursor (AβPP) binding protein that affects AβPP expression.

APP ZFHX3

2.02e-052157225079792
Pubmed

Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation.

APP RYR2

2.02e-052157232966798
Pubmed

Mediator--a universal complex in transcriptional regulation.

MED24 MED13

2.02e-052157211454195
Pubmed

Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.

APP FRA10AC1

2.02e-052157226252872
Pubmed

Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites.

DDX11 RAD17

2.02e-052157230061412
Pubmed

Apoptosis signal-regulating kinase 1 in amyloid beta peptide-induced cerebral endothelial cell apoptosis.

APP MAP3K5

2.02e-052157217522316
Pubmed

Interactome of the amyloid precursor protein APP in brain reveals a protein network involved in synaptic vesicle turnover and a close association with Synaptotagmin-1.

APP SYT1

2.02e-052157222731840
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

RNF166 BAG1 CMSS1 MADD TBK1 HGS RABGEF1 HADHA NGLY1 TDP1 FYB1 USP3

2.09e-056041571238803224
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZDBF2 GTF3C4 NEFM RESF1 SYNJ1 ZNF532 TBK1 ANKRD17 ZFHX3 ARL14EP

2.20e-054181571034709266
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

SEC31A CMSS1 APP FANCD2 ARFGEF3 MED24 PPP2R5E TBK1 MTX3 ANKRD17 HADHA CTNNA1 SCRIB ESPL1 PLOD2

2.60e-059421571531073040
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SGIP1 MAP1B NUDT21 SYNE1 RAPGEF4 NCAM1 PFKL ARHGAP35 MADD NEFM SLC8A2 PPP2R5E SYNJ1 SACS SYT1 MACF1 HADHA CTNNA1 SCRIB

2.65e-0514311571937142655
Pubmed

FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.

CDK8 MED8 MED24 HADHA MED13

2.85e-0578157525720964
Pubmed

Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.

CDK8 MED8 MED24 MED13

2.91e-0539157438690566
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

SGIP1 MAP1B NCAM1 MADD NEFM SYNJ1 SACS MACF1 CTNNA1

3.06e-05347157917114649
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

BMS1 E2F3 KMT2C TRANK1 ZNF532 SUPT6H SETBP1 ANKRD17 AKAP11 ESPL1 MED13

3.09e-055291571114621295
Pubmed

Structure, function, and activator-induced conformations of the CRSP coactivator.

CDK8 MED24 MED13

3.17e-0514157311834832
Pubmed

A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation.

CDK8 MED24 MED13

3.17e-0514157310024883
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

LIAS BMS1 FAM227B PFKL PARP14 ESCO1 RPS6KC1 KMT2C MDN1 TBK1 HADHA SCRIB BANK1

3.21e-057361571329676528
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

CDK8 NUDT21 SLC26A2 ZDBF2 SEC31A FANCD2 MED24 NBAS KMT2C PPP2R5E CHEK2 CKAP2L MFN2 ANKRD17 RABGEF1 NOP2 USP3 MED13

3.32e-0513271571832694731
Pubmed

Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.

CDK8 MED24 MED13

3.95e-0515157318418385
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

CDK8 ATAD5 NUDT21 MED8 GTF3C4 FANCD2 MDN1 SGO2 USP3 MED13

4.34e-054531571029656893
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SYNE1 RAPGEF4 NCAM1 NEFM SYNJ1 SACS MACF1 AKAP11

4.44e-05281157828706196
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MTIF3 ISCA1 SYNE1 BMS1 MRPL30 CAT ZDBF2 TTC3 FANCD2 ARFGEF3 NBAS MDN1 MTX3 MFN2 AKAP11 HADHA FASTKD3 ESPL1 NOP2

4.82e-0514961571932877691
Pubmed

Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.

ESCO1 FANCD2 CHEK2 CKAP2L ESPL1

4.82e-0587157533798452
Pubmed

The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs.

CDK8 MED24 MED13

4.84e-0516157310882111
Pubmed

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

CDK8 MED24 MED13

5.86e-0517157310235266
Pubmed

Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization.

MAP1B NEFM

6.06e-053157211581286
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

NEFM MACF1

6.06e-053157212399109
Pubmed

CMYA5 establishes cardiac dyad architecture and positioning.

CMYA5 RYR2

6.06e-053157235449169
Pubmed

Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2.

ESCO1 DDX11

6.06e-053157231935221
Pubmed

BAG-1M co-activates BACE1 transcription through NF-κB and accelerates Aβ production and memory deficit in Alzheimer's disease mouse model.

BAG1 APP

6.06e-053157228502705
Pubmed

Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system.

NAT2 NEFM

6.06e-053157217896208
Pubmed

The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1.

PPP2R5A PPP2R5E

6.06e-053157221878643
Pubmed

The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons.

RAPGEF4 PLCE1

6.06e-053157228209735
Pubmed

Mitofusin 1 and 2 overexpression reduces AβO-mediated ER stress and apoptosis in N2a APPswe cells.

APP MFN2

6.06e-053157239097901
Pubmed

Mediator kinase module and human tumorigenesis.

CDK8 MED13

6.06e-053157226182352
Pubmed

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

APP RYR2

6.06e-053157228476886
Pubmed

Functional and Structural Insights into a Vif/PPP2R5 Complex Elucidated Using Patient HIV-1 Isolates and Computational Modeling.

PPP2R5A PPP2R5E

6.06e-053157232847850
Pubmed

Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism.

CPB2 F5

6.06e-053157212368162
Pubmed

Amyloid beta-derived neuroplasticity in bone marrow-derived mesenchymal stem cells is mediated by NPY and 5-HT2B receptors via ERK1/2 signalling pathways.

HTR2B APP

6.06e-053157219614678
Pubmed

Procarboxypeptidase U (TAFI) contributes to the risk of thrombosis in patients with hereditary thrombophilia.

CPB2 F5

6.06e-053157219195685
Pubmed

The AICD fragment of APP initiates a FoxO3a mediated response via FANCD2.

APP FANCD2

6.06e-053157235901928
Pubmed

Synaptotagmins interact with APP and promote Aβ generation.

APP SYT1

6.06e-053157226202512
Pubmed

Synaptic vesicle and synaptic membrane glycoproteins during pre- and postnatal development of mouse cerebral cortex, cerebellum and spinal cord.

NCAM1 SYT1

6.06e-05315728168438
Pubmed

Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke.

RAPGEF4 PLCE1

6.06e-053157225103224
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

NUDT21 DHX40 BMS1 SEC31A ARHGAP35 ARFIP1 DNAJC2 HGS CKAP2L MACF1

6.11e-054721571038943005
Pubmed

A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.

CDK8 MED8 MED24 MED13

6.13e-0547157415175163
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

CARMIL3 CAT F5 MADD DNAJC2 MAP3K5 RPS6KC1 SYNJ1 SUPT6H NOP2

6.44e-054751571031040226
Pubmed

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

CDK8 MED24 MED13

7.01e-0518157310198638
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

KIZ SYNE1 ESCO1 GTF3C4 NBAS PPP2R5A PPP2R5E ZFP1 CHEK2 SGO2 HADHA CTNNA1 SCRIB ESPL1 NOP2 PLOD2

7.29e-0511551571620360068
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

CAT ZDBF2 GTF3C4 JAK1 PPP3CC POLR3E HGS CHEK2 ZFHX3 SCRIB TBX2

7.39e-055831571129844126
Pubmed

A human MAP kinase interactome.

SYNE1 SEC31A MADD MAP3K5 KMT2C MAP4K5 HGS ANKRD17 MACF1 CTNNA1

7.78e-054861571020936779
Pubmed

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

ERCC6 CAT ESCO1 FANCD2 SGO2 RAD17

8.28e-05157157630686591
Pubmed

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.

CDK8 MED24 MED13

8.29e-0519157316799563
Pubmed

Shugoshin collaborates with protein phosphatase 2A to protect cohesin.

PPP2R5A PPP2R5E SGO2

8.29e-0519157316541025
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SGIP1 MAP1B NCAM1 ARHGAP35 NEFM MACF1 BRWD1

9.12e-05231157716452087
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ERCC6 HTR2B RAPGEF4 GTF3C4 KMT2C TAOK3 TRANK1 MDN1 XIRP2 CTNNA1

9.35e-054971571036774506
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

SYNE1 XIRP2 MACF1

9.72e-0520157321689717
Pubmed

Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.

CDK8 MED24 MED13

9.72e-0520157315340084
Pubmed

Human chromosome 21 gene expression atlas in the mouse.

NCAM1 PFKL APP TTC3 SYNJ1 BRWD1

1.02e-04163157612466854
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

NUDT21 DHX40 RNF113A ARHGAP35 GTF3C4 SYNJ1 PRIM1 CKAP2L HADHA NOP2

1.08e-045061571030890647
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

CDK8 MED8 MED24 KMT2C RESF1 MED13

1.16e-04167157620362541
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MAP1B ATAD5 NUDT21 SEC31A PFKL ARHGAP35 TTC3 ANKRD17 MACF1 HADHA ESPL1 NOP2

1.18e-047241571236232890
Pubmed

Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.

RAPGEF4 PLCE1

1.21e-044157221041529
Pubmed

Reduced expression of Na+/Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice.

APP SLC8A2

1.21e-044157229274751
Pubmed

Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2.

NCAM1 NEFM

1.21e-04415728622766
Pubmed

Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres.

PPP2R5E SGO2

1.21e-044157220889715
InteractionACAD11 interactions

CDK8 DCAF8L2 MED8 CAT APP JAK1 MED24 POLR3E HADHA MED13

5.16e-0716115610int:ACAD11
Cytoband21q22.2

TTC3 SYNJ1 BRWD1

1.99e-0433157321q22.2
GeneFamilyCyclins|Mediator complex

CDK8 MED8 MED24 MED13

2.94e-05339841061
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP3 CMYA5 AKAP11

5.09e-0429983396
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

CDK8 MAP1B E2F3 ARHGAP35 APP DNAJC2 NBAS TAOK3 PPP2R5A PPP2R5E MDN1 SACS MAP4K5 ANKRD17 MACF1 AKAP11 ZFHX3 PLOD2 MED13 PLCE1

2.18e-0785615720M4500
CoexpressionGSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_DN

ATE1 ARHGAP35 KMT2E TTC3 ESCO1 KMT2C PPP2R5A ZFP1 PNRC1 SERAC1

3.78e-0720015710M9260
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

RNF166 NUDT21 SLC26A2 SYNE1 GRK6 ARHGAP35 KMT2E PARP14 JAK1 KMT2C TAOK3 TRANK1 PPP2R5E RESF1 PPP3CC SACS GFOD1 TBK1 MACF1 PNRC1 AKAP11 NGLY1 FYB1 MED13 BRWD1

2.95e-06149215725M40023
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_EARLY_STALK_CELL

MAP1B ATAD5 GRK6 DDX11 FANCD2 SACS PRIM1 CHEK2 CKAP2L SGO2 SERAC1 TDP1 ESPL1 PHYHIPL

8.62e-0656715714M45692
CoexpressionGSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_UP

LRRN1 SLC35D2 ZNF621 C1GALT1 CMSS1 FRA10AC1 SACS SGO2

2.79e-051991578M10018
CoexpressionPARENT_MTOR_SIGNALING_UP

LIAS SYNE1 MADD MAP3K5 NBAS TRANK1 RESF1 SUPT6H SYT1 PNRC1 HADHA SCRIB BRWD1

3.94e-0556715713M16909
CoexpressionGSE11386_NAIVE_VS_MEMORY_BCELL_DN

SYNE1 RAPGEF4 CMYA5 MAP3K5 MDN1 PLOD2 BANK1

4.84e-051581577M372
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

ERCC6 GIN1 KIZ ESCO1 MADD MAP3K5 FANCD2 KMT2C FRA10AC1 TRANK1 MDN1 PPP3CC PDP1 PRIM1 CHEK2 SGO2 AKAP11 ESPL1 PHYHIPL BRWD1

1.71e-0682015220gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

CDK8 SGIP1 GIN1 ATAD5 ASPN CAT C1GALT1 ZDBF2 PRDM5 DNAJC2 CCDC112 FRA10AC1 MDN1 RESF1 PRIM1 MTX3 CKAP2L MACF1 SGO2 ZFHX3 PRPF39 USP3 RAD17 TBX2 BRWD1

2.52e-06124115225facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

LRRN1 MAP1B GIN1 ATAD5 NCAM1 ZDBF2 CMSS1 KMT2E MADD NEFM CCDC112 FRA10AC1 TAOK3 SETBP1 PRPF39 PHYHIPL

1.93e-0565415216Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

ERCC6 GIN1 DHX40 KIZ PLEKHF2 BMS1 MAP3K5 FANCD2 FRA10AC1 MDN1 PDP1 CHEK2 SGO2 AKAP11 ESPL1 FYB1 NOP2 RAD17

2.06e-0581015218gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CDK8 LRRN1 GIN1 ATAD5 DHX40 E2F3 CAT C1GALT1 ZDBF2 DNAJC2 FANCD2 MDN1 PRIM1 MTX3 SETBP1 CKAP2L MACF1 SGO2 ZFHX3 PRPF39 PHYHIPL USP3 BRWD1

3.11e-05125715223facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

CDK8 LRRN1 MAP1B GIN1 ATAD5 DHX40 E2F3 CAT C1GALT1 ZDBF2 DNAJC2 FANCD2 NEFM MDN1 PRIM1 MTX3 SETBP1 CKAP2L MACF1 SGO2 ZFHX3 PRPF39 PHYHIPL USP3 BRWD1

4.01e-05145915225facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500

CDK8 SGIP1 GIN1 ATAD5 ASPN CAT C1GALT1 ZDBF2 PRDM5 DNAJC2 CCDC112 FRA10AC1 MDN1 RESF1 PRIM1 MTX3 CKAP2L MACF1 SGO2 ZFHX3 PRPF39 USP3 RAD17 TBX2 BRWD1

4.43e-05146815225facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

LRRN1 MAP1B GIN1 ATAD5 CARMIL3 ZDBF2 CMSS1 KMT2E MADD NEFM CCDC112 TAOK3 TRPM5 MDN1 SETBP1 FYB1 PRPF39 PHYHIPL TBX2

7.94e-0598315219Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

LRRN1 MAP1B GIN1 ATAD5 ZDBF2 MADD NEFM TAOK3 SETBP1 PHYHIPL

1.31e-0432815210Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#5_top-relative-expression-ranked_200

MAP1B RYR2 SERAC1 PRPF39 MED13

1.37e-04691525gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k5
CoexpressionAtlasdev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000

SGIP1 MAP1B RAPGEF4 NCAM1 ZDBF2 NEFM NBAS SYT1 PHYHIPL

1.82e-042781529gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_200

SPTLC3 SGIP1 MAP1B RYR2 SERAC1 PRPF39 MED13

1.97e-041661527gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

SGIP1 LRRN1 ASPN NCAM1 CAT CMSS1 KMT2E PRDM5 CCDC112 FRA10AC1 TRPM5 PPP3CC MAP4K5 SETBP1 NGLY1 TAF11 PHYHIPL PLOD2 BANK1 PLCE1

2.07e-04114815220facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

ERCC6 TRANK1 PPP3CC PDP1

2.08e-04411524gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_1000
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B CARMIL3 RAPGEF4 SEC31A TTC3 MADD KMT2C SYNJ1 MACF1

3.26e-0819515793e519cffa6144a62b06124642a14c9ff39b76554
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CARMIL3 MRPL30 NCAM1 CMYA5 KMT2C TRPM5 ZFHX3 FYB1

1.52e-0716815788072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAP1B TRPC5 ZDBF2 TTC3 ARFGEF3 TRANK1 SYNJ1 SYT1

4.06e-0719115785d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAP1B TRPC5 ZDBF2 TTC3 ARFGEF3 TRANK1 SYNJ1 SYT1

4.06e-07191157873dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAP1B TRPC5 ZDBF2 TTC3 ARFGEF3 TRANK1 SYNJ1 SYT1

4.22e-0719215784c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATAD5 CMSS1 DDX11 FANCD2 CHEK2 CKAP2L SGO2 ESPL1

4.39e-0719315784b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B CARMIL3 RAPGEF4 SEC31A TTC3 MADD KMT2C MACF1

4.75e-0719515787796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B NCAM1 ARFGEF3 NEFM CCDC112 SYT1 PHYHIPL TBX2

5.13e-071971578fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

LIAS ATAD5 ASPN ATE1 PRDM5 F5 RYR2

2.27e-0616815771bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

LIAS ATAD5 ASPN ATE1 PRDM5 F5 RYR2

2.27e-06168157769f534de0f9a293047bea03cb1b78551087a8df5
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC31A CMYA5 ESCO1 RYR2 XIRP2 MACF1 HADHA

3.09e-061761577749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAM1 ZDBF2 CMYA5 TRDN ARFGEF3 NEFM XIRP2

3.33e-061781577d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRN1 ZDBF2 CMYA5 TRDN ARFGEF3 ST8SIA6 XIRP2

3.46e-0617915774135f9e8cd8494cbc189e5210dded84659643fb8
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP1B NCAM1 CMYA5 F5 TRDN RYR2 XIRP2

4.00e-0618315772902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B3 MAP1B CARMIL3 NEFM CCDC112 SYT1 TBX2

4.30e-061851577ef996f4cdbc3971c6c0460d13df64b075ab22154
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B3 MAP1B CARMIL3 NEFM CCDC112 SYT1 TBX2

4.30e-061851577d51342a3979bd728a80e04126059a3fd8a0dbe3b
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MAP1B CARMIL3 ZDBF2 TTC3 TRANK1 SYNJ1 SYT1

4.45e-0618615779d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MAP1B ZDBF2 TTC3 ARFGEF3 TRANK1 SYNJ1 SYT1

4.45e-0618615773f889083fcffe516388e9b03a5e23af2010ced33
ToppCelldroplet-Pancreas|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRN1 MAP1B CARMIL3 NCAM1 ZDBF2 ARFGEF3 TRPM5

4.61e-0618715775f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MAP1B CARMIL3 ZDBF2 TTC3 TRANK1 SYNJ1 SYT1

4.78e-061881577b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP1B ASPN SYNE1 RYR2 SYT1 ZFHX3 TBX2

4.95e-0618915777ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATAD5 DDX11 FANCD2 PRIM1 CKAP2L SGO2 ESPL1

5.12e-061901577d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP1B ASPN SYNE1 RYR2 SYT1 ZFHX3 TBX2

5.30e-06191157708042952431ca1a6fd7dfc13f36eb28643979598
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

MAP1B TTC3 MADD TRANK1 SYNJ1 SYT1 AKAP11

5.87e-0619415778aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MDN1 PPP3CC SACS POLR3E AKAP11 PRPF39 BANK1

6.07e-061951577a4d36654b968acb1aea252ac203683939461f1d1
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MDN1 PPP3CC SACS POLR3E AKAP11 PRPF39 BANK1

6.07e-061951577cd811abd949ef201aef1c8515da5575ab1b1cfea
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B RAPGEF4 ARFGEF3 NEFM CCDC112 SYT1 TBX2

6.07e-061951577b25c534fc6320d4da6437ef1b27e32a5d5256f3e
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B RAPGEF4 ARFGEF3 NEFM CCDC112 SYT1 TBX2

6.49e-0619715778951787ed1f7ac1772a6ef0ba2dd44c51fd3c47b
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP1B SYNE1 RAPGEF4 TTC3 RYR2 SETBP1 SYT1

6.71e-061981577c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP1B SYNE1 RAPGEF4 TTC3 RYR2 SETBP1 SYT1

6.71e-0619815776d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGIP1 MAP1B ARFGEF3 NEFM CCDC112 SYT1 TBX2

6.71e-061981577dac7b68bb8f1c4d8aa7fdfada61f79956866e874
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

MTIF3 SLC26A2 SEC31A KMT2E TTC3 PPP2R5E MAP4K5

6.93e-06199157753ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

MTIF3 MAP1B KMT2E TTC3 PPP2R5E MAP4K5 BRWD1

6.93e-061991577c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

MAP1B NCAM1 APP TTC3 ARFGEF3 NEFM SYT1

6.93e-061991577058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

MTIF3 KIZ C1GALT1 SEC31A CMSS1 TTC3 PPP2R5E

6.93e-061991577a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RAPGEF4 APP PARP14 PPP2R5A RESF1 MACF1 CTNNA1

7.16e-06200157772ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RAPGEF4 APP PARP14 PPP2R5A RESF1 MACF1 CTNNA1

7.16e-0620015775c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Cortical_neuron|5w / Sample Type, Dataset, Time_group, and Cell type.

MAP1B NCAM1 NEFM CCDC112 SYT1 ZFHX3 PHYHIPL

7.16e-062001577085060d148158f7d9e938b6c4a3700ccbb3bca15
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal|2m / Sample Type, Dataset, Time_group, and Cell type.

MAP1B NCAM1 TTC3 NEFM CCDC112 GFOD1 SYT1

7.16e-06200157760b86c4a4e247b2673d31b085b440a6e574393bb
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

APP PARP14 MYCBPAP PPP2R5A RESF1 MACF1 CTNNA1

7.16e-06200157779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellVE|World / Condition, Cell_class and T cell subcluster

GRK6 PARP14 JAK1 TRANK1 RESF1 MACF1 PNRC1

7.16e-0620015778ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellhealthy_donor|World / Disease condition, Lineage, Cell class and subclass

SYNE1 NCAM1 KMT2E JAK1 RESF1 MACF1 PNRC1

7.16e-062001577afd4d5609adaa470e3d880f8be4a4d55e162b3d6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Neuronal|1m / Sample Type, Dataset, Time_group, and Cell type.

MAP1B NCAM1 TTC3 NEFM CCDC112 SYT1 PHYHIPL

7.16e-062001577418821561c8949ed96c07f9bea3aabc287c04ff1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Cortical_neuron|1m / Sample Type, Dataset, Time_group, and Cell type.

MAP1B NCAM1 TTC3 NEFM CCDC112 SYT1 PHYHIPL

7.16e-0620015770185b4ad6b512d24efff806460ee1b57e42096e9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal|5w / Sample Type, Dataset, Time_group, and Cell type.

MAP1B NCAM1 NEFM CCDC112 SYT1 ZFHX3 PHYHIPL

7.16e-0620015779b5753726c17dda98d7384a60f26a5eaf4f6c4d6
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

MAP1B ASPN SYNE1 RYR2 SYT1 ZFHX3 PLCE1

7.16e-0620015778bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SGIP1 MAP1B ASPN SYNE1 SYT1 ZFHX3 PLCE1

7.16e-06200157777631c471cc5d453a749784f838cfa6408caf09b
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLC26A2 NCAM1 CMYA5 SYT1 ZFHX3 TBX2

2.01e-051571576b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO5C TRPM5 ST8SIA6 ZFHX3 ESPL1 FYB1

2.40e-05162157680619a93c57fe16daf91dc571874ef9ac888953d
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLPP5 CARMIL3 NBAS PPP3CC CKAP2L SYT1

2.57e-051641576b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLPP5 CARMIL3 NBAS PPP3CC CKAP2L SYT1

2.57e-051641576a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

NCAM1 CMYA5 TRDN RYR2 XIRP2 FYB1

3.14e-0517015764232fe937909f93d3736988c707b8f95ce993398
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LARGE2 CCDC168 ARFGEF3 TRPM5 SYT1 ESPL1

3.14e-05170157698d13dbd76a826e47d55553f9d11f71c043b573e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS SETBP1 AKAP11 FASTKD3 PRPF39 BANK1

3.14e-05170157632917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LRRIQ3 LRRN1 ATAD5 SACS CKAP2L ESPL1

3.46e-05173157620889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LRRIQ3 LRRN1 ATAD5 SACS CKAP2L ESPL1

3.46e-05173157646e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAM1 FANCD2 SLC8A2 CKAP2L SGO2 PLCE1

3.58e-05174157641eb0a214a8b4015a26311f77061c8147144f0e7
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

LARGE2 LRRIQ3 ATAD5 MYO5C ARFGEF3 CKAP2L

3.69e-051751576fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SGIP1 ASPN CHEK2 CKAP2L SGO2 ZFHX3

3.69e-0517515763e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

LARGE2 LRRIQ3 ATAD5 MYO5C ARFGEF3 CKAP2L

3.69e-05175157636c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGIP1 MAP1B NEFM PHYHIPL PLCE1 TBX2

3.93e-051771576452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 ASPN FANCD2 CKAP2L SGO2 ESPL1

4.32e-051801576401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATAD5 DDX11 FANCD2 CKAP2L SGO2 ESPL1

4.32e-051801576334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 NCAM1 APP F5 CKAP2L SGO2

4.46e-051811576566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 NCAM1 APP F5 CKAP2L SGO2

4.46e-051811576db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGIP1 MAP1B RYR2 ZFHX3 PLCE1 TBX2

4.74e-0518315768a799807fbf24456a9811e0c64068187940a2f71
ToppCellfacs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHX40 ARFGEF3 NBAS ST8SIA6 NGLY1 PLCE1

4.74e-051831576b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

MYCBPAP DDX11 FANCD2 CKAP2L SGO2 ESPL1

4.74e-051831576df8568751205313d149939ea2683097e3652a60b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRDN RYR2 ARFGEF3 TRANK1 XIRP2 PLCE1

4.88e-0518415762cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGIP1 MAP1B RYR2 ZFHX3 PLCE1 TBX2

4.88e-051841576689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PFKL GFOD1 CKAP2L SGO2 ESPL1 NOP2

4.88e-051841576185b49630da61cbf45c0926d1b992943296d2a54
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRDN RYR2 ARFGEF3 TRANK1 XIRP2 PLCE1

4.88e-051841576ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRDN RYR2 ARFGEF3 TRANK1 XIRP2 PLCE1

4.88e-0518415762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRPL30 CMYA5 KMT2C TRPM5 ZFHX3 FYB1

5.03e-051851576686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATP8B3 ATAD5 CARMIL3 CKAP2L SGO2 ESPL1

5.03e-0518515769d424a8608b339dd6129c58d87626678d4ec4af7
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ERCC6 GTF3C4 PRDM11 MDN1 MTX3 CKAP2L

5.19e-0518615765cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 FANCD2 CHEK2 CKAP2L SGO2 ESPL1

5.34e-0518715769351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ATP8B3 ATAD5 CCDC168 CKAP2L SGO2 ESPL1

5.50e-051881576319fbeca200ab998daf49fcaee0bfdb57bf7ee4b
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B RAPGEF4 NCAM1 TTC3 MADD ARFGEF3

5.50e-051881576a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATAD5 DDX11 FANCD2 CKAP2L SGO2 ESPL1

5.67e-0518915761e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP1B NCAM1 CMYA5 TRDN RYR2 XIRP2

5.83e-051901576918ad5037881212008f9f69d5df5da91fd01422c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 PRDM5 PRIM1 CKAP2L SGO2 ESPL1

5.83e-051901576b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1B ASPN KMT2E JAK1 MACF1 BANK1

5.83e-051901576d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellDividing_Macrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ATAD5 PRIM1 CHEK2 CKAP2L SGO2 ESPL1

6.01e-0519115763e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPN SYNE1 RYR2 SYT1 ZFHX3 TBX2

6.01e-0519115767853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHF2 GRK6 C1GALT1 BANK1 MED13 BRWD1

6.18e-0519215762de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B RAPGEF4 ARFGEF3 NEFM SYT1 TBX2

6.18e-051921576d8f5df2c2a50e567f24ebecc8033ac97ba89d9c5
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B NEFM CCDC112 SYT1 PHYHIPL TBX2

6.18e-051921576307d64ef7add6a2778733e9945a1bd687feb6f44
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP1B ASPN RYR2 SYT1 ZFHX3 TBX2

6.18e-051921576992d08092edbc68c47b945deb8708379738c239a
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHF2 GRK6 C1GALT1 BANK1 MED13 BRWD1

6.18e-051921576ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B RAPGEF4 ARFGEF3 NEFM SYT1 TBX2

6.36e-0519315769661ea0ee7273928c7de2a9f49e853595fa77699
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 MADD NEFM SLC8A2 TRANK1 SYT1

6.36e-051931576be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 MADD NEFM SLC8A2 TRANK1 SYT1

6.36e-0519315760c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 MADD NEFM SLC8A2 TRANK1 SYT1

6.36e-0519315768689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellCF-Lymphoid|CF / Disease state, Lineage and Cell class

PMS2P1 MDN1 PPP3CC SETBP1 AKAP11 BANK1

6.36e-05193157611de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCell3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

ATAD5 FANCD2 PRIM1 CKAP2L SGO2 ESPL1

6.55e-051941576a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATAD5 FANCD2 CHEK2 CKAP2L SGO2 ESPL1

6.55e-051941576f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LRRIQ3 ATAD5 NCAM1 FAM227B FANCD2 ZFP1

6.55e-0519415768f4b63b0b9a40765205e4ca6bd94a675a83dbe3d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ATAD5 FANCD2 CHEK2 CKAP2L SGO2 ESPL1

6.74e-051951576926eb3fc5d028be936885bea0654a77db3107234
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ATAD5 FANCD2 CHEK2 CKAP2L SGO2 ESPL1

6.74e-0519515761a5e814e12fe37287dbfc58189e1958e2c76b5da
DiseaseIntellectual Disability

CDK8 MAP1B SYNE1 RNF113A E2F3 KMT2E KMT2C SACS SETBP1 SYT1 MACF1 SERAC1 ARL14EP MED13

8.91e-0844715214C3714756
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ERCC6 MADD MAP3K5 JAK1 NEFM PPP2R5E MFN2

1.79e-051571527DOID:224 (biomarker_via_orthology)
Diseaseprostate cancer (is_implicated_in)

NAT2 CYP17A1 BAG1 JAK1 CHEK2 ZFHX3

3.31e-051171526DOID:10283 (is_implicated_in)
Diseasehypothyroidism (biomarker_via_orthology)

MAP1B NCAM1 CAT NEFM PLOD2

5.98e-05801525DOID:1459 (biomarker_via_orthology)
DiseaseCatecholaminergic polymorphic ventricular tachycardia 1

TRDN RYR2

7.88e-0531522cv:C1631597
DiseaseVENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1, WITH OR WITHOUT ATRIAL DYSFUNCTION AND/OR DILATED CARDIOMYOPATHY

TRDN RYR2

7.88e-0531522604772
Diseasecoffee consumption measurement, Cannabis use

NCAM1 BANK1

1.57e-0441522EFO_0006781, EFO_0007585
DiseasePremature aging syndrome

ERCC6 APP

1.57e-0441522C0231341
DiseaseEctodermal Dysplasia

DHX40 BMS1

3.90e-0461522C0013575
DiseaseAmenorrhea

CYP17A1 CPB2

3.90e-0461522C0002453
Diseasequality of life during menstruation measurement, breast pressure measurement

MAP1B ANKRD17

3.90e-0461522EFO_0009366, EFO_0009393
DiseaseETS domain-containing protein Elk-3 measurement

SLC35D2 MFN2

3.90e-0461522EFO_0801588
Disease2-myristoyl-GPC (14:0) measurement

ESCO1 MAP4K5

3.90e-0461522EFO_0800242
Disease1-myristoyl-GPC (14:0) measurement

ESCO1 MAP4K5

3.90e-0461522EFO_0800221
DiseasePostpartum Amenorrhea

CYP17A1 CPB2

3.90e-0461522C0032796
Diseasepyruvate decarboxylase deficiency (is_implicated_in)

LIAS PDP1

3.90e-0461522DOID:3649 (is_implicated_in)
DiseaseWAP four-disulfide core domain protein 3 measurement

SLC35D2 MFN2

3.90e-0461522EFO_0802220
Diseaseacid ceramidase measurement

SLC35D2 MFN2

3.90e-0461522EFO_0801339
Diseaselon protease homolog, mitochondrial measurement

SLC35D2 MFN2

3.90e-0461522EFO_0801771
Diseaseneural cell adhesion molecule 1, 120 kda isoform measurement

NCAM1 MAP4K5

3.90e-0461522EFO_0020593
Diseaseacute promyelocytic leukemia (is_marker_for)

NCAM1 KMT2E

3.90e-0461522DOID:0060318 (is_marker_for)
Diseasechloride measurement

MAP4K5 SYT1 TBX2

4.44e-04291523EFO_0009284
Diseaseinterleukin-17 receptor B measurement

SLC35D2 MFN2

5.44e-0471522EFO_0801719
Diseasefree cholesterol to total lipids in large LDL percentage

NAT2 MAP4K5 MACF1 BANK1

5.89e-04741524EFO_0022280
DiseaseBorderline personality disorder

CCDC168 TRDN SYT1

7.77e-04351523HP_0012076
Diseaselung non-small cell carcinoma (is_implicated_in)

ERCC6 E2F3 JAK1 KMT2C ZFHX3

7.84e-041391525DOID:3908 (is_implicated_in)
DiseaseMalignant tumor of prostate

CHEK2 ZFHX3

9.27e-0491522cv:C0376358
Diseaselung adenocarcinoma (is_marker_for)

ERCC6 E2F3 KMT2C PLOD2

9.91e-04851524DOID:3910 (is_marker_for)
Diseasecarboxypeptidase B2 measurement

CPB2 TMEM232

1.15e-03101522EFO_0008069
Diseaseosteonecrosis (is_implicated_in)

CAT F5

1.15e-03101522DOID:10159 (is_implicated_in)
DiseaseVENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)

TRDN RYR2

1.15e-03101522C1631597
Diseasebeta-nerve growth factor measurement

LRRN1 F5 ST8SIA6

1.33e-03421523EFO_0008035
Diseasesenile cataract (is_implicated_in)

NAT2 CAT

1.41e-03111522DOID:9669 (is_implicated_in)
Diseasepeptidyl-glycine alpha-amidating monooxygenase measurement

GIN1 GRK6

1.41e-03111522EFO_0801871
Diseaselevel of Phosphatidylcholine (14:0_18:1) in blood serum

ESCO1 MAP4K5

1.68e-03121522OBA_2045062
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

NAT2 E2F3 MAP4K5 USP3 BRWD1

1.73e-031661525EFO_0004530, EFO_0004611
Diseasesciatic neuropathy (biomarker_via_orthology)

CYP17A1 CAT JAK1 NEFM

1.74e-03991524DOID:11446 (biomarker_via_orthology)
Diseasefatty acid measurement

ANKRD31 NAT2 E2F3 ESCO1 MAP4K5 MACF1 PLOD2 BRWD1

1.97e-034361528EFO_0005110
DiseasetRNA (guanine-N(7)-)-methyltransferase measurement

GRK6 MAP4K5

1.98e-03131522EFO_0802162
DiseaseLeukemia, Myelocytic, Acute

FANCD2 JAK1 KMT2C SETBP1 CTNNA1

2.07e-031731525C0023467
Diseasecholesteryl esters to total lipids in IDL percentage

MAP4K5 MACF1 BANK1

2.20e-03501523EFO_0022247
DiseaseChromosome Breakage

CAT DDX11

2.30e-03141522C0376628
Diseasetriacylglycerol 46:2 measurement

DNAJC2 MAP4K5

2.30e-03141522EFO_0010402
DiseaseChromosome Breaks

CAT DDX11

2.30e-03141522C0333704
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

ANKRD31 NAT2 E2F3 MAP4K5 MACF1 TAF11

2.53e-032641526EFO_0008317, EFO_0020944
Diseaseaspartate aminotransferase measurement

ANKRD31 SLC26A2 C1GALT1 FAM227B ARHGAP35 MADD ST8SIA6 GFOD1 MAP4K5 CHEK2 BANK1 PLCE1

2.58e-0390415212EFO_0004736
Diseasematrix metalloproteinase 1 measurement

PRIM1 CKAP2L

2.65e-03151522EFO_0010588
Diseaseglucose homeostasis measurement, glucose effectiveness measurement

MYO5C MAP4K5

2.65e-03151522EFO_0006833, EFO_0006896
Diseasecancer (implicated_via_orthology)

PPP2R5A PPP2R5E MACF1 SCRIB NOP2 TBX2

2.73e-032681526DOID:162 (implicated_via_orthology)
Diseaseserum gamma-glutamyl transferase measurement

NAT2 SGIP1 C4orf50 FAM227B ARHGAP35 RYR2 TRANK1 MAP4K5 CHEK2 USP3 MED13 PLCE1

2.82e-0391415212EFO_0004532
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

MTIF3 E2F3 CMSS1 SETBP1 MACF1 ZFHX3 PLCE1

2.89e-033641527EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseDiffuse Large B-Cell Lymphoma

CAT SEC31A PRDM11

2.89e-03551523C0079744
Diseasecentral nervous system disease (implicated_via_orthology)

SEC31A TAOK3

3.02e-03161522DOID:331 (implicated_via_orthology)
DiseaseAlzheimer's disease (biomarker_via_orthology)

NCAM1 APP MFN2

3.36e-03581523DOID:10652 (biomarker_via_orthology)
DiseaseBipolar Disorder

SYNE1 BAG1 NCAM1 PFKL APP NEFM TRANK1 PPP3CC

3.41e-034771528C0005586
Diseasecholesteryl esters to total lipids in large HDL percentage

NAT2 MADD MAP4K5

3.53e-03591523EFO_0022248
Diseasecholesterol to total lipids in IDL percentage

MAP4K5 MACF1 BANK1

3.70e-03601523EFO_0022233
DiseaseMalignant neoplasm of breast

NAT2 ERCC6 SYNE1 CYP17A1 BAG1 C4orf50 CAT TTC3 ZNF532 SETBP1 CHEK2 MACF1 FASTKD3

3.80e-03107415213C0006142
DiseaseMyeloid Leukemia

KMT2E SETBP1

3.82e-03181522C0023470
DiseaseLeukemia, Monocytic, Chronic

KMT2E SETBP1

3.82e-03181522C0023466
DiseaseC-reactive protein measurement

NAT2 SGIP1 IL37 CCDC168 MADD JAK1 TRANK1 MAP4K5 MACF1 CTNNA1 ARL14EP FYB1 USP3 BANK1

3.90e-03120615214EFO_0004458
DiseaseCerebrovascular accident

APP F5 ZFHX3

4.06e-03621523C0038454
Diseaselysophosphatidylcholine measurement

ESCO1 MAP4K5 SYT1

4.06e-03621523EFO_0010224
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

CHEK2 CTNNA1

4.26e-03191522C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

CHEK2 CTNNA1

4.26e-03191522C2936783
Diseaseoptic disc size measurement

CMSS1 F5 CHEK2 MACF1 PLCE1

4.28e-032051525EFO_0004832
DiseaseCardiomyopathies

CAT APP RYR2 MAP3K5

4.65e-031301524C0878544
Diseasediet measurement, body mass index

CMYA5 FRA10AC1

4.71e-03201522EFO_0004340, EFO_0008111
Diseasetotal lipids in very large HDL measurement

MADD MAP4K5 BANK1

4.84e-03661523EFO_0022312
Diseasephospholipids in very large HDL measurement

MADD MAP4K5 BANK1

4.84e-03661523EFO_0022298
DiseaseMYELODYSPLASTIC SYNDROME

FANCD2 SETBP1 CTNNA1

5.04e-03671523C3463824

Protein segments in the cluster

PeptideGeneStartEntry
KKCQFLEKILHSPKS

BANK1

96

Q8NDB2
LKAEHKQFLVKVLIP

PPP2R5E

256

Q16537
QDVKSTKLITKPKHQ

C2orf16

561

Q68DN1
KKYFPLLLKKQIEHQ

ATAD5

961

Q96QE3
KDFRILQAKATKKPH

FAM227B

446

Q96M60
LQAKATKKPHEVKQD

FAM227B

451

Q96M60
IHALQKKAYLVKNKP

HTR2B

241

P41595
NVKKLQHQLKDVKPT

CCDC112

51

Q8NEF3
KLKEKADNTPVLFHN

CCDC112

241

Q8NEF3
HLKDAQIFIQKKAVK

CAT

466

P04040
KNLPKADKKAVIQHF

APP

421

P05067
CDPFNIHKKLAKKNL

ARL14EP

76

Q8N8R7
KQLEQTLKQFHIKLK

ARFIP1

346

P53367
DGKVIKLFAKHIKVQ

CMSS1

181

Q9BQ75
KNSPQEEVELKKLKH

BAG1

221

Q99933
LKESAKDQPLKKHNL

AKAP11

1036

Q9UKA4
KTSKSEPNHVIFKKI

SAG

6

P10523
PKQKALIVALVKKYH

ATP8B3

916

O60423
LLKKKPPQQQHHKAK

ANKRD17

61

O75179
ILKKLNHPCIIKIKN

CHEK2

276

O96017
NKDSLYKPILRQKKH

BMS1

1146

Q14692
LQKLDPHQKDDINKK

DNAJC2

506

Q99543
HRHFKNKVPEKQKLF

COX7A2P2

21

O60397
KKITAKQKHLQAILG

ERCC6

186

Q03468
NKLTKIHPKAFLTTK

ASPN

136

Q9BXN1
KPETQHELAVHKKKI

RAD17

96

O75943
KHIFNAIKITKNEPA

RABGEF1

296

Q9UJ41
TSINVFRKKHQKPKS

IQCM

46

A0A1B0GVH7
RHKPNVVSVEKEKNK

JAK1

326

P23458
NSPKKLRVKNKHVEF

LARGE2

341

Q8N3Y3
KKFPVKQALQRHVLQ

PRDM5

206

Q9NQX1
ASKLTNHVELFKKPQ

ANKRD31

1021

Q8N7Z5
KKITAKQKHLQAILG

ERCC6

186

P0DP91
KVRFPKVQLQEHLKQ

MTX3

211

Q5HYI7
AVNKIKQLLKDKPEH

ISCA1

31

Q9BUE6
EVLEKHFKKKLCPQS

MDN1

1321

Q9NU22
NKTLVLSDKHSPQKK

KMT2C

2801

Q8NEZ4
HQEVKKQKALEKQRP

MADD

1126

Q8WXG6
KHLDFLKQPLATQKD

MAP1B

506

P46821
VQKSHKNCFPEILKK

MAGEB3

141

O15480
HLIFPKKASVEQLQK

NGLY1

86

Q96IV0
KEVKKPTLAKVHLQQ

RPS6KC1

431

Q96S38
LQQHHVKLETKPKKF

CARMIL3

26

Q8ND23
KKENNGVLKKFTPHH

DCAF8L2

401

P0C7V8
DLLLQKPFQKEKHGK

FRA10AC1

31

Q70Z53
KHLVQITIKKGKNVD

MTIF3

186

Q9H2K0
KPFKNTENIKNSHLK

PNRC1

251

Q12796
KLLAHQKPPKEKSNF

PFKL

386

P17858
TEFLHTKNNPKKDLK

CYLC1

211

P35663
KKKFKLTGPIQVIHL

FYB1

501

O15117
PVESHIQKNKKILKS

KMT2E

331

Q8IZD2
PDKIKLQLSKHKEFQ

MACF1

2711

O94854
VLKHAKKVQPDVISK

LIAS

261

O43766
LPVHHKEFQRNIKKK

PMS2P1

366

A4D2B8
ARKKIFQEPKSAHQV

DDX11

731

Q96FC9
SRHENKKKPVINLKS

KIZ

626

Q2M2Z5
VFNPAKELIAKLEKH

RNF113A

306

O15541
KIFQHSKPDLQQKII

NBAS

971

A2RRP1
KLEHPKSEAKSVVKQ

PDP1

326

Q9P0J1
HLFKIQKNLPKSRKV

PRPF39

501

Q86UA1
SNDPDKIKLQLSKHK

MACF1

6581

Q9UPN3
ASPLKHFVTAKKKIN

MFN2

26

O95140
GPEEVLKKFQKANHK

PLOD2

121

O00469
QDVKKKVHLSEKIHP

PRIM1

196

P49642
SPQKKNHLVLEKKTE

PARP14

1411

Q460N5
QKKQHEAKLAVTPLK

C4orf50

61

Q6ZRC1
LDSVKKVHLQKGKQQ

ESPL1

1071

Q14674
VHTSPKVKNLNPKKF

IL37

46

Q9NZH6
KVKNLNPKKFSIHDQ

IL37

51

Q9NZH6
EGIHLIKKKSKNNVQ

E2F3

226

O00716
KIKRASQKKHVNPVQ

CTNNA1

881

P35221
PVTADLIVKKKQVHF

CPB2

56

Q96IY4
HNLSAFPKEVKVEKK

ARFGEF3

2036

Q5TH69
EKVTPLKENKQKETH

CMYA5

3011

Q8N3K9
LKIFPNKTLEKLKSH

CYP17A1

221

P05093
IQKHKDNKKLPQGII

CASC2

31

Q8IU53
KKITDQLLKFIKNQH

BRWD1

1251

Q9NSI6
TNKEFLNSHLLPKKK

NAT2

171

P11245
LPKKKHQKIYLFTLE

NAT2

181

P11245
PLQFQPSKSHKKVLK

ATE1

81

O95260
KNKFGAPQKDVKHLA

HADHA

351

P40939
GPQNLEKKAKHVKAT

C1GALT1

96

Q9NS00
KLSQKKLVHENPKAN

ESCO1

101

Q5FWF5
KAALLDKNGKKHPQV

FTCDNL1

31

E5RQL4
HKSLLEQFTPKEKNK

CCDC168

6401

Q8NDH2
TKPKEHKKLFLVQLQ

NUDT21

166

O43809
EVKEHPLFKKLNFKR

GRK6

441

P43250
KVKPDSKAFHLLQKL

CDK8

301

P49336
KLFQEKSPNRKEHLK

DHX40

191

Q8IX18
DFFKKLEQLIKPKNH

SACS

3561

Q9NZJ4
IINKVKPQLLKTHFL

RYR2

3306

Q92736
DIPHLSAKIKPKQQK

POLR3E

41

Q9NVU0
QPLSKKTKKSHIANE

FANCD2

26

Q9BXW9
KFLDLNKNPIHKIQE

LRRN1

266

Q6UXK5
HNFVKIALTKNPKKR

MAP4K5

251

Q9Y4K4
KKKYNKQHIIPLENV

PLEKHF2

71

Q9H8W4
KVLKHEKTPLFRNQV

MED8

61

Q96G25
EKDQEIKHLKLKSQP

MAP3K5

1276

Q99683
NKFKHKDVPTKLVAK

PHYHIPL

96

Q96FC7
KKKFETKVHRKTLNP

SYT1

191

P21579
DAKAPQKKHKVLLQQ

RAPGEF4

636

Q8WZA2
KLNKIIHFPDFDKKI

SLC35D2

76

Q76EJ3
VNHLNICKPKKKDAF

SERAC1

621

Q96JX3
KNIPSVNAKLKVVKH

MRPL30

101

Q8TCC3
SKQHIPEKKNEVHKV

SYNE1

2546

Q8NF91
KLHSVLKPQVQKFLD

SYNJ1

346

O43426
DIIKVHFKNKADKPL

F5

96

P12259
KAVKVHGLLKTFVKQ

GFOD1

191

Q9NXC2
NQPHKKTKITFEEDK

NBPF15

221

Q8N660
LLKNKKLKAHQTPVD

PLCE1

1536

Q9P212
KLKAHQTPVDILKQK

PLCE1

1541

Q9P212
FDPKKVDKATHVEKQ

RNF166

76

Q96A37
KRQENKHKTFLPVKG

RESF1

1611

Q9HCM1
SKGQIPNSKHKKIIF

TAF11

196

Q15544
KNKPLNHVHKVVKER

FASTKD3

26

Q14CZ7
AKNTVIVAPKQHLLK

GIN1

121

Q9NXP7
VHPQAKKKKIDLIFK

PRDM11

326

Q9NQV5
LKIPQVLVKLKKYSH

MED24

311

O75448
GKEKENPLLVKIHFK

SPATA32

361

Q96LK8
VESKKEIPIKKNIFH

ST8SIA6

156

P61647
HKLEKDNLLPNQKDK

SGO2

541

Q562F6
KEVKFLRQLKHPNTI

TAOK3

71

Q9H2K8
IVHLPQIIALKKKYK

SPTLC3

316

Q9NUV7
KKHFKISKLPQPEAV

SCRIB

611

Q14160
QILPKHKTNEKQEKS

MED13

451

Q9UHV7
LQKQQHPKKASFQKL

NOP2

636

P46087
EQKLHALKEVLKKFP

ARHGAP35

1351

Q9NRY4
ALKEVLKKFPKENHE

ARHGAP35

1356

Q9NRY4
ALPLKAEHKQFLMKV

PPP2R5A

261

Q15172
FAKKVPEHVRKAQDK

AKAP3

386

O75969
KLKKAVPQNHFLNKT

CKAP2L

421

Q8IYA6
QDATIHLKVFAKPKI

NCAM1

296

P13591
LKKFLLNKKPHVVTV

SUPT6H

836

Q7KZ85
KHIKDNKNDFSPKVE

XIRP2

2256

A4UGR9
HEHLKNKSAPKVVKQ

XIRP2

2666

A4UGR9
KPKVDVLKNHLVKEG

PPP3CC

36

P48454
AQKAAHKRKISPVKF

TDP1

51

Q9NUW8
IFKHQKIKNLVQPFI

ZFP1

171

Q6P2D0
QPLKKLKINVFKVHK

ZNF532

1161

Q9HCE3
KNLIQHKKIHTGEKP

ZIM3

376

Q96PE6
DFKKSKGPQQIHLKA

RGS18

121

Q9NS28
HLLVPKVAEKQFKEK

TRPM5

271

Q9NZQ8
AKPVAFHKLKLTNNI

TBX2

201

Q13207
LPTKELNEHFKSKLK

SLC26A2

316

P50443
EESHKKFNIKIKPLQ

SGIP1

111

Q9BQI5
PNKKLESVKKQVLHF

TMEM232

551

C9JQI7
VNSIKKKVNDKNPHV

HGS

46

O14964
HKPFQDKLVLSTAQK

PLPP5

241

Q8NEB5
PQLAFLKEKHVNLKD

ZDBF2

1056

Q9HCK1
TEHILDEQKKKKPNP

TTC3

1891

P53804
KKQQEALSEHLKKPV

MYCBPAP

216

Q8TBZ2
KILKDKHIPQFLQEA

GTF3C4

546

Q9UKN8
KHIPQFLQEALEKKI

GTF3C4

551

Q9UKN8
VPLTNHKKSEKQDKV

USP3

66

Q9Y6I4
QHQKLHPVEKKPVKV

ZNF621

336

Q6ZSS3
QEKPERKIQTKVTHK

TRDN

151

Q13061
LIKHQKIHTKQKPYK

ZNF484

791

Q5JVG2
PQKYHDLAKLKVAIK

TRPC5

281

Q9UL62
KPKVKVSFKNHSALI

ITFG1

86

Q8TB96
KQCAVRKPKKIHQLY

TRANK1

1451

O15050
FQHVQSLPTKKITKK

SEC31A

1096

O94979
ELPLVSEKNKHKEKQ

SETBP1

1196

Q9Y6X0
FEVLKKLNHKNIVKL

TBK1

56

Q9UHD2
SQHPEKKNKLVIKEK

ZFHX3

1871

Q15911
VRKNLSPVFFHKKKQ

LRRIQ3

231

A6PVS8
SPVFFHKKKQQEKII

LRRIQ3

236

A6PVS8
IQILKDLKQKHPDKD

SLC8A2

316

Q9UPR5
VKSAKQVIKPNSKHF

MYO5C

606

Q9NQX4
IQKPKVEAPKLKVQH

NEFM

436

P07197