Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium channel activity	TRPV1 TRPC4AP TSPOAP1 GRIA1 ITPR2 TRPV4	2.36e-04	129	134	6	GO:0005262
GeneOntologyMolecularFunction	3',5'-cyclic-AMP phosphodiesterase activity	PDE2A PDE6A PDE1B	4.14e-04	22	134	3	GO:0004115
GeneOntologyMolecularFunction	DNA/RNA hybrid binding	POLR1A POLR3B	4.41e-04	5	134	2	GO:0071667
GeneOntologyMolecularFunction	3',5'-cyclic-GMP phosphodiesterase activity	PDE2A PDE6A PDE1B	5.39e-04	24	134	3	GO:0047555
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPV1 TRPC4AP TSPOAP1 GRIA1 ITPR2 TRPV4	5.49e-04	151	134	6	GO:0015085
GeneOntologyMolecularFunction	3',5'-cyclic-nucleotide phosphodiesterase activity	PDE2A PDE6A PDE1B	6.10e-04	25	134	3	GO:0004114
GeneOntologyMolecularFunction	cyclic-nucleotide phosphodiesterase activity	PDE2A PDE6A PDE1B	7.68e-04	27	134	3	GO:0004112
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH3 MYH11 ATAD5 SMCHD1 SMARCAL1 PSMC2 MSH5 MYO5C UBA1 CLPB RAD17 DNAH11	8.93e-04	614	134	12	GO:0140657
GeneOntologyMolecularFunction	calmodulin binding	TRPV1 MYH11 PDE1B MYO5C PPP3CC SCN3A TRPV4	9.35e-04	230	134	7	GO:0005516
GeneOntologyMolecularFunction	DNA-directed 5'-3' RNA polymerase activity	MED20 POLR1A POLR3B	1.05e-03	30	134	3	GO:0003899
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	TRPV1 GRIA1 ITPR2	1.16e-03	31	134	3	GO:0099604
GeneOntologyMolecularFunction	5'-3' RNA polymerase activity	MED20 POLR1A POLR3B	1.27e-03	32	134	3	GO:0034062
GeneOntologyMolecularFunction	RNA polymerase activity	MED20 POLR1A POLR3B	1.27e-03	32	134	3	GO:0097747
GeneOntologyCellularComponent	site of double-strand break	SLF1 SMCHD1 SMARCAL1 WDR70 UFL1 CNTD1 RAD17	4.16e-06	101	135	7	GO:0035861
GeneOntologyCellularComponent	site of DNA damage	SLF1 SMCHD1 SMARCAL1 WDR70 UFL1 CNTD1 RAD17	3.07e-05	137	135	7	GO:0090734
Domain	P-loop_NTPase	IFT27 DNAH3 CMPK1 MYH11 SAMD9 RAB17 ATAD5 SMARCAL1 PSMC2 MSH5 PFKFB3 MYO5C ARHGAP5 SAMD9L TRANK1 CLPB MTHFD1 SRL GNAT2 RAD17 DNAH11	5.15e-07	848	132	21	IPR027417
Domain	-	IFT27 DNAH3 CMPK1 SAMD9 RAB17 ATAD5 SMARCAL1 PSMC2 MSH5 PFKFB3 ARHGAP5 SAMD9L TRANK1 CLPB MTHFD1 SRL GNAT2 RAD17 DNAH11	1.26e-06	746	132	19	3.40.50.300
Domain	EF-hand-dom_pair	TBC1D9B CALB2 CAPSL DGKB SLC25A13 SCN3A AIF1 TNNC2 MICU2 PLS1	3.77e-05	287	132	10	IPR011992
Domain	EF_HAND_2	TBC1D9B CALB2 CAPSL DGKB SLC25A13 AIF1 TNNC2 MICU2 PLS1	3.94e-05	231	132	9	PS50222
Domain	EF_hand_dom	TBC1D9B CALB2 CAPSL DGKB SLC25A13 AIF1 TNNC2 MICU2 PLS1	4.07e-05	232	132	9	IPR002048
Domain	TRPV4_channel	TRPV1 TRPV4	4.96e-05	2	132	2	IPR008348
Domain	-	TBC1D9B CALB2 CAPSL DGKB SLC25A13 AIF1 TNNC2 MICU2 PLS1	1.01e-04	261	132	9	1.10.238.10
Domain	EF-hand_1	CALB2 CAPSL DGKB SLC25A13 TNNC2 MICU2 PLS1	1.04e-04	152	132	7	PF00036
Domain	EFh	CALB2 CAPSL DGKB SLC25A13 TNNC2 MICU2 PLS1	1.32e-04	158	132	7	SM00054
Domain	1Cnucl_rcpt	PPARA PPARG	1.48e-04	3	132	2	IPR003074
Domain	TRPV1-4_channel	TRPV1 TRPV4	2.95e-04	4	132	2	IPR008347
Domain	PDEase	PDE2A PDE6A PDE1B	3.08e-04	19	132	3	IPR023088
Domain	EF-hand_7	CALB2 CAPSL DGKB TNNC2 PLS1	3.41e-04	85	132	5	PF13499
Domain	PDEase_I	PDE2A PDE6A PDE1B	4.18e-04	21	132	3	PF00233
Domain	PDEASE_I	PDE2A PDE6A PDE1B	4.18e-04	21	132	3	PS00126
Domain	PDEase_CS	PDE2A PDE6A PDE1B	4.18e-04	21	132	3	IPR023174
Domain	-	PDE2A PDE6A PDE1B	4.82e-04	22	132	3	1.10.1300.10
Domain	Myosin_S1_N	MYH11 MYO5C	4.89e-04	5	132	2	IPR008989
Domain	PDEase_catalytic_dom	PDE2A PDE6A PDE1B	5.51e-04	23	132	3	IPR002073
Domain	AAA	DNAH3 ATAD5 PSMC2 CLPB RAD17 DNAH11	5.59e-04	144	132	6	SM00382
Domain	AAA+_ATPase	DNAH3 ATAD5 PSMC2 CLPB RAD17 DNAH11	5.59e-04	144	132	6	IPR003593
Domain	EF_HAND_1	CALB2 CAPSL DGKB SLC25A13 AIF1 TNNC2 PLS1	6.24e-04	204	132	7	PS00018
Domain	HD/PDEase_dom	PDE2A PDE6A PDE1B	6.26e-04	24	132	3	IPR003607
Domain	HDc	PDE2A PDE6A PDE1B	6.26e-04	24	132	3	SM00471
Domain	Keratin_II	KRT84 KRT80 KRT76	7.97e-04	26	132	3	IPR003054
Domain	CRAL_TRIO	MCF2 MCF2L SEC14L5	8.91e-04	27	132	3	PS50191
Domain	CRAL-TRIO_dom	MCF2 MCF2L SEC14L5	9.93e-04	28	132	3	IPR001251
Domain	GAF	PDE2A PDE6A	1.02e-03	7	132	2	PF01590
Domain	GAF	PDE2A PDE6A	1.35e-03	8	132	2	IPR003018
Domain	GAF	PDE2A PDE6A	1.35e-03	8	132	2	SM00065
Pubmed	Human mannose-binding lectin 2 is directly regulated by peroxisome proliferator-activated receptors via a peroxisome proliferator responsive element.	MBL2 PPARA PPARG	2.28e-07	4	135	3	23711995
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	MYH11 SLF1 USP9X KRT84 GARS1 LARS1 PSMC2 FAM98A MSI1 KRT80 UBA1 KRT76 MTHFD1 G3BP2 SLC25A13 SCN3A PLS1 RPL13	5.60e-07	1153	135	18	29845934
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH11 PDE6A ZMPSTE24 KRT84 SMCHD1 GARS1 GRIA1 FAM98A PPARA HMOX2 TTC3 GSR KRT76 KIAA0825 SLC25A13 UGGT2 MCF2L PLS1 RPL13	3.25e-06	1442	135	19	35575683
Pubmed	Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13.	KRT84 KRT80 KRT76	4.72e-06	9	135	3	15737194
Pubmed	A proteome-scale map of the SARS-CoV-2-human contactome.	TRIM2 USP9X PPARA F13A1 KRT80 G3BP2 UGGT2	5.41e-06	173	135	7	36217029
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	CMPK1 GARS1 LARS1 PSMC2 FAM98A TTC3 ITPR2 CELSR1 UBA1 HPX SNX18 PLS1 SPINK5	5.95e-06	732	135	13	34732716
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PDE2A USP9X LARS1 ARFGEF2 SIAH1 VPS54 HMOX2 TTC3 SYNGAP1 ARHGAP5 GMCL1 POLR3B ACAD8 CLPB RNF216 LRBA RPL13	1.06e-05	1285	135	17	35914814
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	PDE2A MYH11 USP9X LARS1 ARFGEF2 DGKB GRIA1 FAM98A ITPR2 SYNGAP1 ARHGAP5 UBA1 KRT76 WASHC5 MTHFD1 G3BP2 RPL13 DNAH11	1.13e-05	1431	135	18	37142655
Pubmed	Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand.	PPARA PPARG	1.50e-05	2	135	2	15731109
Pubmed	Possible involvement of TRPV1 and TRPV4 in nociceptive stimulation- induced nocifensive behavior and neuroendocrine response in mice.	TRPV1 TRPV4	1.50e-05	2	135	2	26314785
Pubmed	Potent anti-diabetic effects of MHY908, a newly synthesized PPAR α/γ dual agonist in db/db mice.	PPARA PPARG	1.50e-05	2	135	2	24244369
Pubmed	Trpv4 Mediates Hypotonic Inhibition of Central Osmosensory Neurons via Taurine Gliotransmission.	TRPV1 TRPV4	1.50e-05	2	135	2	29791836
Pubmed	Peroxisome proliferator-activated receptors-alpha and gamma are targets to treat offspring from maternal diet-induced obesity in mice.	PPARA PPARG	1.50e-05	2	135	2	23700465
Pubmed	Roles of peroxisome proliferator-activated receptor-alpha and -gamma in the development of non-small cell lung cancer.	PPARA PPARG	1.50e-05	2	135	2	20081051
Pubmed	Germline loss-of-function SAMD9 and SAMD9L alterations in adult myelodysplastic syndromes.	SAMD9 SAMD9L	1.50e-05	2	135	2	30322869
Pubmed	The conserved residue Phe273(282) of PPARalpha(gamma), beyond the ligand-binding site, functions in binding affinity through solvation effect.	PPARA PPARG	1.50e-05	2	135	2	15935279
Pubmed	PPAR(alpha) and PPAR(gamma) activators suppress the monocyte-macrophage apoB-48 receptor.	PPARA PPARG	1.50e-05	2	135	2	12700342
Pubmed	Mouse germ cell-less as an essential component for nuclear integrity.	GMCL1 GMCL2	1.50e-05	2	135	2	12556490
Pubmed	Temperature-activated ion channels in neural crest cells confer maternal fever-associated birth defects.	TRPV1 TRPV4	1.50e-05	2	135	2	29018170
Pubmed	The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells.	TRPV1 TRPV4	1.50e-05	2	135	2	21562271
Pubmed	Dynamic and permissive roles of TRPV1 and TRPV4 channels for thermosensation in mouse supraoptic magnocellular neurosecretory neurons.	TRPV1 TRPV4	1.50e-05	2	135	2	24155319
Pubmed	Regulation of the Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens.	TRPV1 TRPV4	1.50e-05	2	135	2	34884463
Pubmed	Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice.	PPARA PPARG	1.50e-05	2	135	2	17536062
Pubmed	Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage.	HMOX2 HPX	1.50e-05	2	135	2	26831741
Pubmed	Variations in the genes encoding the peroxisome proliferator-activated receptors alpha and gamma in psoriasis.	PPARA PPARG	1.50e-05	2	135	2	15083308
Pubmed	PPARγ2 gene Pro12Ala and PPARα gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations.	PPARA PPARG	1.50e-05	2	135	2	22378291
Pubmed	Functional roles of TRPV1 and TRPV4 in control of lower urinary tract activity: dual analysis of behavior and reflex during the micturition cycle.	TRPV1 TRPV4	1.50e-05	2	135	2	25761879
Pubmed	85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells.	PPARA PPARG	1.50e-05	2	135	2	11897617
Pubmed	PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation.	PPARA PPARG	1.50e-05	2	135	2	20852389
Pubmed	Association between PPARs Gene Functional Polymorphisms and Ischemic Stroke in Chinese Uyghur Population.	PPARA PPARG	1.50e-05	2	135	2	30697628
Pubmed	Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4.	TRPV1 TRPV4	1.50e-05	2	135	2	21994383
Pubmed	Oxygenized low density lipoprotein down-regulates the TRPV4 protein expression of macrophage through activation of peroxisome proliferator-activated receptor γ.	PPARG TRPV4	1.50e-05	2	135	2	27706112
Pubmed	Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression.	PPARA PPARG	1.50e-05	2	135	2	16357043
Pubmed	PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis.	PPARA PPARG	1.50e-05	2	135	2	11934839
Pubmed	SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies.	SAMD9 SAMD9L	1.50e-05	2	135	2	29535429
Pubmed	How Does Ginsenoside Rh2 Mitigate Adipogenesis in Cultured Cells and Obese Mice?	PPARG GSR	1.50e-05	2	135	2	32455850
Pubmed	Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy.	PPARA PPARG	1.50e-05	2	135	2	12594295
Pubmed	Tumor suppressor control of the cancer stem cell niche.	PPARA PPARG	1.50e-05	2	135	2	26686086
Pubmed	Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans.	PPARA PPARG	1.50e-05	2	135	2	25516156
Pubmed	Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes.	SAMD9 SAMD9L	1.50e-05	2	135	2	34621053
Pubmed	Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells.	SAMD9 SAMD9L	1.50e-05	2	135	2	33731850
Pubmed	Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function.	PPARA PPARG	1.50e-05	2	135	2	32130908
Pubmed	Sonic hedgehog signaling instigates high-fat diet-induced insulin resistance by targeting PPARγ stability.	PPARG NEDD4	1.50e-05	2	135	2	30573683
Pubmed	Enhanced muscle by myostatin propeptide increases adipose tissue adiponectin, PPAR-alpha, and PPAR-gamma expressions.	PPARA PPARG	1.50e-05	2	135	2	18312853
Pubmed	Dominant-negative loss of PPARgamma function enhances smooth muscle cell proliferation, migration, and vascular remodeling.	PPARA PPARG	1.50e-05	2	135	2	19179641
Pubmed	[Pancytopenia in children caused by SAMD9/9L mutation: 5 cases report and literature review].	SAMD9 SAMD9L	1.50e-05	2	135	2	37357006
Pubmed	Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels.	TRPV1 TRPV4	1.50e-05	2	135	2	26146187
Pubmed	PPAR α and PPAR γ polymorphisms as risk factors for dyslipidemia in a Chinese Han population.	PPARA PPARG	1.50e-05	2	135	2	24460649
Pubmed	Molecular cloning and genomic organization of mouse homologue of Drosophila germ cell-less and its expression in germ lineage cells.	GMCL1 GMCL2	1.50e-05	2	135	2	10448096
Pubmed	A Val227Ala polymorphism in the peroxisome proliferator activated receptor alpha (PPARalpha) gene is associated with variations in serum lipid levels.	PPARA PPARG	1.50e-05	2	135	2	11897821
Pubmed	Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice.	PPARA PPARG	1.50e-05	2	135	2	25557389
Pubmed	PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice.	PPARA PPARG	1.50e-05	2	135	2	37479780
Pubmed	TRPV1 activation inhibits phenotypic switching and oxidative stress in vascular smooth muscle cells by upregulating PPARα.	TRPV1 PPARA	1.50e-05	2	135	2	33550097
Pubmed	Combined effects of PPARgamma2 P12A and PPARalpha L162V polymorphisms on glucose and insulin homeostasis: the Québec Family Study.	PPARA PPARG	1.50e-05	2	135	2	14677049
Pubmed	[Effects of Pollen Typhae total flavones on mRNA expressions of peroxisome proliferator-activated receptors in 3T3-L1 adipocytes].	PPARA PPARG	1.50e-05	2	135	2	18782538
Pubmed	[Transient receptor potential (TRP) channel and cough].	TRPV1 TRPV4	1.50e-05	2	135	2	18552442
Pubmed	Gluten-free diet reduces adiposity, inflammation and insulin resistance associated with the induction of PPAR-alpha and PPAR-gamma expression.	PPARA PPARG	1.50e-05	2	135	2	23253599
Pubmed	PPARγ and PPARα synergize to induce robust browning of white fat in vivo.	PPARA PPARG	1.50e-05	2	135	2	32248079
Pubmed	PPARα-mediated peroxisome induction compensates PPARγ-deficiency in bronchiolar club cells.	PPARA PPARG	1.50e-05	2	135	2	30212482
Pubmed	A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection.	SAMD9 SAMD9L	1.50e-05	2	135	2	29447249
Pubmed	Genetic deficiency in Pparg does not alter development of experimental prostate cancer.	PPARA PPARG	1.50e-05	2	135	2	12960963
Pubmed	Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response.	PFKFB3 PPARG	1.50e-05	2	135	2	22841546
Pubmed	Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse.	SAMD9 SAMD9L	1.50e-05	2	135	2	17407603
Pubmed	APOE dependent-association of PPAR-γ genetic variants with Alzheimer's disease risk.	PPARA PPARG	1.50e-05	2	135	2	19660836
Pubmed	Nedd4-mediated AMPA receptor ubiquitination regulates receptor turnover and trafficking.	GRIA1 NEDD4	1.50e-05	2	135	2	21338354
Pubmed	Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach.	PPARA PPARG	1.50e-05	2	135	2	22685582
Pubmed	Role of the PPARalpha Leu162Val and PPARgamma2 Pro12Ala gene polymorphisms in weight change after 2.5-year follow-up in Czech obese women.	PPARA PPARG	1.50e-05	2	135	2	20653996
Pubmed	Fatty liver and anti-oxidant enzyme activities along with peroxisome proliferator-activated receptors γ and α expressions in the liver of Wilson's disease.	PPARA PPARG	1.50e-05	2	135	2	22940187
Pubmed	TRPV1 and TRPV4 channels: potential therapeutic targets for ischemic conditioning-induced cardioprotection.	TRPV1 TRPV4	1.50e-05	2	135	2	25449039
Pubmed	Recurrent activations of transient receptor potential vanilloid-1 and vanilloid-4 promote cellular proliferation and migration in esophageal squamous cell carcinoma cells.	TRPV1 TRPV4	1.50e-05	2	135	2	30761248
Pubmed	TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.	TRPV1 TRPV4	1.50e-05	2	135	2	23021218
Pubmed	PPARalpha and PPARgamma attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities.	PPARA PPARG	1.50e-05	2	135	2	19141539
Pubmed	Molecular mechanism of PPAR in the regulation of age-related inflammation.	PPARA PPARG	1.50e-05	2	135	2	18313368
Pubmed	P633H, a novel dual agonist at peroxisome proliferator-activated receptors alpha and gamma, with different anti-diabetic effects in db/db and KK-Ay mice.	PPARA PPARG	1.50e-05	2	135	2	19422369
Pubmed	The PPARα and PPARγ Epigenetic Landscape in Cancer and Immune and Metabolic Disorders.	PPARA PPARG	1.50e-05	2	135	2	34638914
Pubmed	Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma.	TRPV1 TRPV4	1.50e-05	2	135	2	20639579
Pubmed	Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family.	PPARA PPARG	1.50e-05	2	135	2	11587644
Pubmed	Osmoregulatory thirst in mice lacking the transient receptor potential vanilloid type 1 (TRPV1) and/or type 4 (TRPV4) receptor.	TRPV1 TRPV4	1.50e-05	2	135	2	25100078
Pubmed	Aleglitazar, a dual peroxisome proliferator-activated receptor-α and -γ agonist, protects cardiomyocytes against the adverse effects of hyperglycaemia.	PPARA PPARG	1.50e-05	2	135	2	28111985
Pubmed	Peroxisome proliferator-activated receptors family is involved in the response to treatment and mild clinical course in patients with ulcerative colitis.	PPARA PPARG	1.50e-05	2	135	2	25548431
Pubmed	Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors α/γ agonists.	PPARA PPARG	1.50e-05	2	135	2	23502212
Pubmed	Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation.	PPARA PPARG	1.50e-05	2	135	2	15642120
Pubmed	A retinoid X receptor (RXR)-selective retinoid reveals that RXR-alpha is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands.	PPARA PPARG	1.50e-05	2	135	2	15318936
Pubmed	Plasma mannose-binding lectin is stimulated by PPARα in humans.	MBL2 PPARA	1.50e-05	2	135	2	22215653
Pubmed	Peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms in nonalcoholic fatty liver disease: a study in Brazilian patients.	PPARA PPARG	1.50e-05	2	135	2	23891824
Pubmed	Association of PPAR polymorphisms with cytokine levels in allergic rhinitis.	PPARA PPARG	1.50e-05	2	135	2	21785974
Pubmed	The dual PPARα/γ agonist aleglitazar increases the number and function of endothelial progenitor cells: implications for vascular function and atherogenesis.	PPARA PPARG	1.50e-05	2	135	2	24467636
Pubmed	Increased expression of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma in human atherosclerosis.	PPARA PPARG	1.50e-05	2	135	2	20399568
Pubmed	Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation.	PPARA PPARG	1.50e-05	2	135	2	12900517
Pubmed	The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Pneumococcal Nasal Colonization and Subsequent Development of Invasive Disease.	TRPV1 TRPV4	1.50e-05	2	135	2	34804016
Pubmed	Structural insight into the crucial role of ligand chirality in the activation of PPARs by crystallographic methods.	PPARA PPARG	1.50e-05	2	135	2	21291392
Pubmed	PPARγ induces NEDD4 gene expression to promote autophagy and insulin action.	PPARG NEDD4	1.50e-05	2	135	2	31423749
Pubmed	The Pro12Ala variant of the PPARG gene is a risk factor for peroxisome proliferator-activated receptor-gamma/alpha agonist-induced edema in type 2 diabetic patients.	PPARA PPARG	1.50e-05	2	135	2	16822823
Pubmed	Verification and spatial mapping of TRPV1 and TRPV4 expression in the embryonic and adult mouse lens.	TRPV1 TRPV4	1.50e-05	2	135	2	31229503
Pubmed	Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature.	TRPV1 TRPV4	1.50e-05	2	135	2	25069877
Pubmed	TRPV1 and TRPV4 play pivotal roles in delayed onset muscle soreness.	TRPV1 TRPV4	1.50e-05	2	135	2	23799042
Pubmed	Selective activation of peroxisome proliferator-activated receptor (PPAR)alpha and PPAR gamma induces neoangiogenesis through a vascular endothelial growth factor-dependent mechanism.	PPARA PPARG	1.50e-05	2	135	2	18268046
Pubmed	Peroxisome proliferator-activated receptors (PPARs)-independent functions of fish oil on glucose and lipid metabolism in diet-induced obese mice.	PPARA PPARG	1.50e-05	2	135	2	20846400
Pubmed	Smaller bladder capacity and stronger bladder contractility in patients with ketamine cystitis are associated with elevated TRPV1 and TRPV4.	TRPV1 TRPV4	1.50e-05	2	135	2	33664402
Pubmed	Role of Trpv1 and Trpv4 in surgical incision-induced tissue swelling and Fos-like immunoreactivity in the central nervous system of mice.	TRPV1 TRPV4	1.50e-05	2	135	2	29733975
Cytoband	4q31.3	TRIM2 RNF175 LRBA	1.05e-04	31	135	3	4q31.3
Cytoband	5q15	SLF1 KIAA0825 ERAP2	2.27e-04	40	135	3	5q15
Cytoband	Ensembl 112 genes in cytogenetic band chr5q15	SLF1 KIAA0825 ERAP2	7.17e-04	59	135	3	chr5q15
Cytoband	7q21.2	SAMD9 SAMD9L	8.79e-04	15	135	2	7q21.2
GeneFamily	EF-hand domain containing	TBC1D9B CALB2 CAPSL DGKB SLC25A13 AIF1 TNNC2 MICU2 PLS1	2.27e-06	219	95	9	863
GeneFamily	Phosphodiesterases	PDE2A PDE6A PDE1B	2.63e-04	24	95	3	681
GeneFamily	Keratins, type II	KRT84 KRT80 KRT76	3.75e-04	27	95	3	609
Coexpression	GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN	IFT27 SLF1 SMARCAL1 CALHM2 SERPINI1 CLPB HAUS1 G3BP2	9.67e-06	200	135	8	M7059
Coexpression	ERWIN_COHEN_BLOOD_LIVE_VACCINE_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_14DY_UP	CMPK1 SAMD9 ARFGEF2 PSMC2 UFL1 VPS54 PPWD1 ARHGAP5 EXOC5 RSAD2 SAMD9L HAUS1 ERAP2 MICU2	1.30e-05	687	135	14	M41022
Coexpression	GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP	MYH11 TBC1D9B F13A1 ITPR2 RSAD2 SAMD9L SERPINI1	1.43e-05	152	135	7	M2964
ToppCell	LPS_only-Epithelial_airway-airway_epithelial\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH3 TRPV1 RAB17 RIBC2 CAPSL KRT80 SPINK5 CNDP1	1.68e-07	198	135	8	e035380578c01b0243bfef29ca9b50cc17cce771
ToppCell	LPS_only-Epithelial_airway\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH3 TRPV1 RAB17 RIBC2 CAPSL KRT80 SPINK5 CNDP1	1.68e-07	198	135	8	ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 POLR1A PDE1B CYP8B1 STRA8 AIF1 SP140	6.48e-07	162	135	7	388670cf3acef17df971c0d8ae3ce14398945192
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 POLR1A PDE1B CYP8B1 STRA8 AIF1 SP140	6.48e-07	162	135	7	9333d923225df7bfdf6b3a4c32816751315aec50
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM2 USP9X CERS6 PPARA PPARG GSR ARHGAP5	1.13e-06	176	135	7	1dd54bfaa58541de51e5a8328651d390833bd480
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	SAMD9 USP9X SMCHD1 RSAD2 SAMD9L TRANK1 ERAP2	1.47e-06	183	135	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	facs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 PDE1B DGKB PPARA SERPINI1 SCN3A SPDYA	1.69e-06	187	135	7	f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCell	facs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 PDE1B DGKB PPARA SERPINI1 SCN3A SPDYA	1.69e-06	187	135	7	3ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 ERAP2 SP140	1.75e-06	188	135	7	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 SALL3 GTF2IRD1 MYO5C SEMA6D SCN3A LRBA	1.82e-06	189	135	7	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 SALL3 GTF2IRD1 MYO5C SEMA6D SCN3A LRBA	1.82e-06	189	135	7	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	Mild-CD4+_T_activated\|Mild / Disease group and Cell class	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 ERAP2 SP140	2.31e-06	196	135	7	daa1c3322d81e649161e889e1d78451d2d425d09
ToppCell	368C-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 RIBC2 PPARG ZSWIM1 F13A1 TRANK1	6.55e-06	150	135	6	c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell	368C-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KBTBD3 RIBC2 PPARG ZSWIM1 F13A1 TRANK1	6.55e-06	150	135	6	78b8029e71d26f336a46274c8afef3435bf536b9
ToppCell	Control-Epithelial_airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 RIBC2 KRT80 CELSR1 DNAH11 SPINK5	8.82e-06	158	135	6	35aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell	LPS-IL1RA-Epithelial_airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAB17 CAPSL KRT80 CELSR1 DNAH11 SPINK5	9.82e-06	161	135	6	472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 RIBC2 KRT80 TRPV4 DNAH11 SPINK5	1.09e-05	164	135	6	e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO5C GMCL1 GRK3 TRPV4 XYLB SEC14L5	1.09e-05	164	135	6	cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO5C GMCL1 GRK3 TRPV4 XYLB SEC14L5	1.09e-05	164	135	6	5dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO5C GMCL1 GRK3 TRPV4 XYLB SEC14L5	1.09e-05	164	135	6	f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	ZMPSTE24 EXOC5 MTHFD1 TAAR1 GNAT2	1.17e-05	97	135	5	489f5e12eb67b1850f1f2d7d4b229df1f4ceefe3
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYH11 SLF1 TSPOAP1 DGKB SCN3A HPX	1.17e-05	166	135	6	26f3d5e5e30b63b09b89cda23c423d12d887631f
ToppCell	droplet-Marrow-nan-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F13A1 KRT80 GRK3 KIAA0825 SLC25A13 AIF1	1.48e-05	173	135	6	6d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCell	Severe-CD4+_T_activated\|Severe / Disease group and Cell class	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 ERAP2	1.68e-05	177	135	6	a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH11 PDE6A DGKB CNTD1 SERPINI1 SCN3A	1.68e-05	177	135	6	928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCell	BAL-Control-cDC_1\|Control / Compartment, Disease Groups and Clusters	SAMD9 SMCHD1 RSAD2 SAMD9L POLR3B SP140	1.68e-05	177	135	6	aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 ERAP2	1.79e-05	179	135	6	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 DGKB GTF2IRD1 MYO5C SEMA6D SCN3A	2.29e-05	187	135	6	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 DGKB GTF2IRD1 MYO5C SEMA6D SCN3A	2.43e-05	189	135	6	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 DGKB PRKAG3 SCN3A SRL TNNC2	2.58e-05	191	135	6	f932980baa032748857cb367a55c37dd975c693e
ToppCell	droplet-Bladder-nan-3m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 DGKB RSAD2 SERPINI1 SCN3A MCF2L	2.74e-05	193	135	6	8be24713f8ba2545b7647d1994e9e993623ddaa3
ToppCell	droplet-Bladder-nan-3m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 DGKB RSAD2 SERPINI1 SCN3A MCF2L	2.74e-05	193	135	6	19dfc4a2c91fcea4f5991e7c44df46faeecb06b8
ToppCell	droplet-Bladder-nan-3m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 DGKB RSAD2 SERPINI1 SCN3A MCF2L	2.74e-05	193	135	6	351e0acd411a9eb0dbc0e358d0d1e3759753fa40
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SAMD9 RSAD2 SAMD9L TRANK1 ERAP2 SP140	2.90e-05	195	135	6	662b50a2aa97373bf343b88caace9717049c722a
ToppCell	mild-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SAMD9 ARFGEF2 MSH5 SCN3A CLNK PLS1	2.90e-05	195	135	6	1e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCell	B_cells-ISG-high_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 SP140	2.90e-05	195	135	6	b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell	mild-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 SP140	2.98e-05	196	135	6	ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 ERAP2	2.98e-05	196	135	6	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	Mild-CD4+_T_activated\|World / Disease group and Cell class	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 ERAP2	2.98e-05	196	135	6	417b4fc2e4388f34c410576131b02936f93e46b6
ToppCell	CV-Moderate-1\|CV / Virus stimulation, Condition and Cluster	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 SP140	3.07e-05	197	135	6	e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SAMD9 SMCHD1 RSAD2 TRANK1 ERAP2 RPL13	3.07e-05	197	135	6	0b4fdf0131dd67a86ee3209fa66db0ca2e01a10e
ToppCell	severe-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 SP140	3.07e-05	197	135	6	c8a90d82170cf20e14aebecddcf7cc0ca56cda87
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SAMD9 SMCHD1 RSAD2 TRANK1 ERAP2 RPL13	3.07e-05	197	135	6	b3876076684781fb8384117f2cf367d828985986
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 RIBC2 CAPSL KRT80 CELSR1 SPINK5	3.16e-05	198	135	6	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Mild-CD8+_T_activated\|Mild / Disease group and Cell class	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 SP140	3.16e-05	198	135	6	ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 RIBC2 CAPSL KRT80 CELSR1 SPINK5	3.16e-05	198	135	6	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	CV-Mild-1\|CV / Virus stimulation, Condition and Cluster	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 SP140	3.16e-05	198	135	6	4b078714c49e7befb7b113d72485e712236d35fa
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLF1 GRIA1 CERS6 TTC3 SERPINI1 SCN3A	3.16e-05	198	135	6	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_only / Treatment groups by lineage, cell group, cell type	TRPV1 RAB17 RIBC2 KRT80 SPINK5 CNDP1	3.25e-05	199	135	6	165ac94b2d56072ad43358b5127d77555221e2d8
ToppCell	VE-CD4-antiviral_CD4\|VE / Condition, Cell_class and T cell subcluster	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 SP140	3.25e-05	199	135	6	056a0538ca5e825ae6195b4c76c208708a014533
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Smooth_muscle-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MYH11 DGKB SERPINI1 SEMA6D SCN3A SRL	3.25e-05	199	135	6	2c5ad62919c64ea0242e0984bb9932d2d975f4e3
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 SP140	3.25e-05	199	135	6	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	Tracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYH11 PDE1B DGKB MSI1 SEMA6D SCN3A	3.25e-05	199	135	6	aaa460c389cd6d38a13ba1a446f91a94f9573ad8
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	SAMD9 SMCHD1 RSAD2 SAMD9L TRANK1 NMT1	3.34e-05	200	135	6	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	droplet-Lung-1m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDE2A F13A1 GSR POLR3B SP140	4.44e-05	128	135	5	376102331d79010c1b2ce26e6ab0134c7b8a4ec3
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CERS6 PPARA PPWD1 UBA1 UGT2B7	8.03e-05	145	135	5	47a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell	droplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	F13A1 GSR RSAD2 GRK3 AIF1	9.43e-05	150	135	5	b37f538ca5f976b509efe35dc81115b72b227084
ToppCell	droplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	F13A1 GSR RSAD2 GRK3 AIF1	9.43e-05	150	135	5	2c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 DGKB SERPINI1 SCN3A SRL	1.00e-04	152	135	5	0cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 DGKB SERPINI1 SCN3A SRL	1.00e-04	152	135	5	ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 AFF2 CNTD1 LRBA GNAT2	1.10e-04	155	135	5	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 RIBC2 CAPSL TRPV4 DNAH11	1.10e-04	155	135	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5\|390C / Donor, Lineage, Cell class and subclass (all cells)	TRPV1 PDE6A EXOC5 SAMD9L XYLB	1.10e-04	155	135	5	afdd0aba0f3788c2fb916ffb453c5dd7cde2304c
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 RIBC2 CAPSL TRPV4 DNAH11	1.10e-04	155	135	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SMCHD1 BCCIP PPARA F13A1 AIF1	1.17e-04	157	135	5	eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 DNAH3 RIBC2 KIAA0825 DNAH11	1.17e-04	157	135	5	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	E18.5-Immune-Immune_Myeloid-DC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP47 POLR1A CYP8B1 STRA8 AIF1	1.28e-04	160	135	5	9f1fec2cf565193c73cc3c8a4f0476e57478e3b8
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPARG RSAD2 SEMA6D AIF1 TRPV4	1.28e-04	160	135	5	0544bc465af208da448858d6e174ff56f2e08a46
ToppCell	facs-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPARG KRT80 GSR GRK3 AIF1	1.31e-04	161	135	5	45591addc765760db6029ac19e80573373d1d917
ToppCell	facs-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPARG KRT80 GSR GRK3 AIF1	1.31e-04	161	135	5	8741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCell	facs-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPARG KRT80 GSR GRK3 AIF1	1.31e-04	161	135	5	9cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RSAD2 HPX AIF1 TRPV4 PLS1	1.31e-04	161	135	5	60f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 MCF2 SYNGAP1 SERPINI1 SRL	1.35e-04	162	135	5	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 MCF2 SYNGAP1 SERPINI1 SRL	1.35e-04	162	135	5	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 MCF2 SYNGAP1 SERPINI1 SRL	1.35e-04	162	135	5	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SAMD9 ITPR2 RSAD2 SAMD9L TRANK1	1.39e-04	163	135	5	d005115aa1e1458b51de7eb719794617a4168608
ToppCell	facs-Marrow-T_cells-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPARG F13A1 KRT80 GRK3 AIF1	1.39e-04	163	135	5	30cd95d4f37bd54c1fde54960cb005db58bdd30c
ToppCell	facs-Marrow-T_cells-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPARG F13A1 KRT80 GRK3 AIF1	1.39e-04	163	135	5	ab934cb986495adfc8dbe5a276577f2a8fb6ee03
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLR1A CYP8B1 AIF1 SPDYA CLNK	1.43e-04	164	135	5	5638d95c7cc5e59c4a7bda30268a904a01861a5f
ToppCell	droplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 STRA8 CAPSL PFKFB3 PRKAG3	1.43e-04	164	135	5	78de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAB17 KRT80 CELSR1 DNAH11 SPINK5	1.47e-04	165	135	5	1a114eacaab598f755a173a3fed842ba91f689dd
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAB17 KRT80 CELSR1 DNAH11 SPINK5	1.47e-04	165	135	5	9cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS PPARG GRK3 AIF1 TRPV4	1.52e-04	166	135	5	91eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 SCN3A RPL13 DNAH11 SPINK5	1.65e-04	169	135	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SAMD9 RSAD2 SAMD9L TRANK1 PLS1	1.69e-04	170	135	5	07b561cd9c528bc8444c9385e1de621eee7b697e
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 PDE1B DGKB SERPINI1 SCN3A	1.74e-04	171	135	5	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 PDE1B DGKB SERPINI1 SCN3A	1.74e-04	171	135	5	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLR1A CYP8B1 ARHGAP5 AIF1 CLNK	1.79e-04	172	135	5	a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CPSF4L PDE2A RSAD2 HPX MCF2L	1.84e-04	173	135	5	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	Tuft-tuft-4\|World / Class top	PFKFB3 ZSWIM1 ITPR2 RSAD2 SAMD9L	1.89e-04	174	135	5	d6f306ebf66061bf9e9742000bfedce12d277452
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 CALB2 DGKB SERPINI1 SCN3A	1.89e-04	174	135	5	197686570cec6d96a92e77e6409325d3bfe6f991
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 CALB2 DGKB SERPINI1 SCN3A	1.89e-04	174	135	5	2eee7b5471672b439f95eba11494c2adf8cb7006
ToppCell	droplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1B CYP8B1 AIF1 LRBA CLNK	1.89e-04	174	135	5	2afa5eea54b67c549c5058ece98296eee3829c11
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MED20 POLR1A EXOC5 CLNK SP140	1.94e-04	175	135	5	26bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 PPARG KRT80 SAMD9L GRK3	1.94e-04	175	135	5	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SAMD9 TSPOAP1 RSAD2 SAMD9L TRANK1	2.04e-04	177	135	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SAMD9 TSPOAP1 RSAD2 SAMD9L TRANK1	2.04e-04	177	135	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	356C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CALB2 SLF1 PFKFB3 KIAA0825 CLNK	2.04e-04	177	135	5	7ddd7d1854ad42abd630ad0c702105102cec93e7
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	SAMD9 TSPOAP1 RSAD2 SAMD9L TRANK1	2.04e-04	177	135	5	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SAMD9 TSPOAP1 RSAD2 SAMD9L TRANK1	2.04e-04	177	135	5	936ab2b180a052387124f68d0c7f41c0b164e748
Drug	17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	IFT27 RALGDS DNAH3 TRIM2 AFF2 TSPOAP1 RNF216 GNAT2 SPINK5	2.02e-06	191	134	9	993_UP
Drug	P-NE	PDE2A PDE6A PDE1B GRK3 TNNC2 LRBA GNAT2 CNDP1	7.36e-06	169	134	8	CID000446755
Drug	perfluorodecanoic acid	CYP8B1 MBL2 PPARA PPARG HPX AIF1	1.75e-05	92	134	6	ctd:C036567
Drug	Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; HL60; HT_HG-U133A	TRPC4AP TBC1D9B TSPOAP1 PPARG GTF2IRD1 CALHM2 PPP3CC SP140	1.93e-05	193	134	8	1864_UP
Drug	trifluoperazine	MYH11 PDE1B GARS1 MYO5C PPP3CC GRK3 UGT2B7 TNNC2 XYLB LRBA	2.28e-05	324	134	10	CID000005566
Drug	(2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid	PPARA PPARG	3.44e-05	2	134	2	DB08483
Drug	mono-n-octyl phthalate	PPARA PPARG	3.44e-05	2	134	2	ctd:C041260
Drug	LY 465608	PPARA PPARG	3.44e-05	2	134	2	ctd:C453901
Drug	MHY966	PPARA PPARG	3.44e-05	2	134	2	ctd:C580737
Drug	Gw 9544	PPARA PPARG	3.44e-05	2	134	2	CID000446642
Drug	mono-n-hexyl phthalate	PPARA PPARG	3.44e-05	2	134	2	ctd:C049841
Drug	naveglitazar	PPARA PPARG	3.44e-05	2	134	2	ctd:C517861
Drug	Phenylpropionates	PPARA PPARG	3.44e-05	2	134	2	ctd:D010666
Drug	URB597	TRPV1 PPARA PPARG TRPV4	3.63e-05	32	134	4	CID001383884
Drug	Dietary Sucrose	PDE6A PDE1B CYP8B1 KRT84 PFKFB3 PPARA PPARG GSR SYNGAP1 PRKAG3 KRT76 TRANK1 GRK3 GNAT2 MCF2L CLNK SPINK5	3.95e-05	942	134	17	ctd:D019422
Drug	13-oxooctadecadienoic acid	PPARA PPARG UGT2B7	4.22e-05	12	134	3	CID005283012
Drug	CID11979489	PPARA PPARG GSR	4.22e-05	12	134	3	CID011979489
Drug	chromate	LARS1 GSR CLNK	5.46e-05	13	134	3	CID000024425
Drug	ingenol dibenzoate	CALB2 PPARA PPARG	6.92e-05	14	134	3	CID000162166
Drug	vanadyl	DNAH3 PDE2A PDE1B PTPN2 PPP3CC GRK3 LRBA NMT1 DNAH11	8.76e-05	307	134	9	CID000061671
Drug	Biliton	DNAH3 UGT2B7 MCF2L DNAH11	9.81e-05	41	134	4	CID000002974
Drug	isophorone	TRPV1 PPARG	1.03e-04	3	134	2	ctd:C005940
Drug	indeglitazar	PPARA PPARG	1.03e-04	3	134	2	CID011395145
Drug	didecyl phthalate	PPARA PPARG	1.03e-04	3	134	2	ctd:C027718
Drug	Bezafibrate	PPARA PPARG	1.03e-04	3	134	2	DB01393
Drug	dodecylbenzenesulfonic acid	PPARG GSR	1.03e-04	3	134	2	ctd:C001114
Drug	linoleoyl-coenzyme A	PPARA PPARG	1.03e-04	3	134	2	ctd:C026562
Drug	2,2-dichloro-12-(p-chlorophenyl)-dodecanoic acid	PPARA PPARG	1.03e-04	3	134	2	ctd:C116893
Drug	2-methyl-c-5-(4-(5-methyl-2-(4-methylphenyl)-4-oxazolyl)butyl)-1,3-dioxane-r-2-carboxylic acid	PPARA PPARG	1.03e-04	3	134	2	ctd:C487401
Drug	oleoyl-coenzyme A	PPARA PPARG	1.03e-04	3	134	2	ctd:C017585
Drug	stearoyl-coenzyme A	PPARA PPARG	1.03e-04	3	134	2	ctd:C017725
Drug	ragaglitazar	PPARA PPARG	1.03e-04	3	134	2	ctd:C432703
Drug	Linolenic Acids	TRPV1 PPARA	1.03e-04	3	134	2	ctd:D008042
Drug	5-((2,4-dioxo-5-thiazolidinyl)methyl)-2-methoxy-N-((4-(trifluoromethyl)phenyl)methyl)benzamide	PPARA PPARG	1.03e-04	3	134	2	ctd:C116017
Drug	N-methylpentanamide	PPARA PPARG	1.03e-04	3	134	2	CID000022591
Drug	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid	PPARA PPARG	1.03e-04	3	134	2	DB07724
Drug	gnetin C	PPARA PPARG	1.03e-04	3	134	2	ctd:C575740
Drug	NSC 29059	PPARA PPARG	1.03e-04	3	134	2	CID000097701
Drug	glycerol	POLR1A GARS1 GRIA1 PPARA HMOX2 PPARG PPWD1 GSR BLMH GMCL1 PTPN2 GMCL2 POLR3B SLC25A13 SP140	1.13e-04	829	134	15	CID000000753
Disease	Familial monosomy 7 syndrome	SAMD9 SAMD9L	1.96e-05	2	131	2	cv:C5681220
Disease	familial partial lipodystrophy (implicated_via_orthology)	ZMPSTE24 PPARG	1.96e-05	2	131	2	DOID:0050440 (implicated_via_orthology)
Disease	Crohn's disease of large bowel	PPARA PPARG PTPN2 ERAP2	4.39e-05	44	131	4	C0156147
Disease	IIeocolitis	PPARA PPARG PTPN2 ERAP2	4.39e-05	44	131	4	C0949272
Disease	Crohn's disease of the ileum	PPARA PPARG PTPN2 ERAP2	4.39e-05	44	131	4	C0267380
Disease	Regional enteritis	PPARA PPARG PTPN2 ERAP2	4.39e-05	44	131	4	C0678202
Disease	Bipolar Disorder	IFT27 MBL2 DGKB GRIA1 PFKFB3 NEDD4 TRANK1 PPP3CC GRK3 MTHFD1	5.60e-05	477	131	10	C0005586
Disease	Crohn Disease	PPARA PPARG PTPN2 ERAP2	7.29e-05	50	131	4	C0010346
Disease	Kartagener syndrome (is_implicated_in)	MBL2 DNAH11	1.17e-04	4	131	2	DOID:0050144 (is_implicated_in)
Disease	Dyslipidemias	PPARA PPARG DNAH11	1.62e-04	24	131	3	C0242339
Disease	Dyslipoproteinemias	PPARA PPARG DNAH11	1.62e-04	24	131	3	C0598784
Disease	free androgen index	PDE2A SMCHD1 DGKB PPARA PPARG GTF2IRD1 PRKAG3 PTPN2	2.76e-04	374	131	8	EFO_0007005
Disease	Infection	SAMD9 MBL2	4.05e-04	7	131	2	C3714514
Disease	Reactive hypoglycemia	PPARA GSR	8.60e-04	10	131	2	C0271710
Disease	Fasting Hypoglycemia	PPARA GSR	8.60e-04	10	131	2	C0271708
Disease	Hypoglycemia	PPARA GSR	1.05e-03	11	131	2	C0020615
Disease	Stevens-Johnson syndrome, toxic epidermal necrolysis, response to methazolamide	MSH5 AIF1	1.05e-03	11	131	2	EFO_0004276, EFO_0004775, EFO_0020996
Disease	diastolic blood pressure change measurement	ERAP2 UGT2B7 MICU2	1.44e-03	50	131	3	EFO_0006945
Disease	idiopathic osteonecrosis of the femoral head	SAMD9 PPARG CLNK	1.61e-03	52	131	3	EFO_1001930
Disease	Birth Weight	MBL2 AS3MT	1.72e-03	14	131	2	C0005612
Disease	factor VII measurement	TRPC4AP NEDD4 MCF2L	1.90e-03	55	131	3	EFO_0004619
Disease	Charcot-Marie-Tooth disease type 2	GARS1 TRPV4	2.55e-03	17	131	2	cv:C0270914
Disease	obsolete_red blood cell distribution width	RALGDS CPSF4L SAMD9 POLR1A GARS1 AS3MT BCCIP CERS6 PPARG GMCL1 HAUS1 G3BP2 NMT1 PLS1	2.69e-03	1347	131	14	EFO_0005192
Disease	schizophrenia (implicated_via_orthology)	PPARA SYNGAP1 TAAR1	3.47e-03	68	131	3	DOID:5419 (implicated_via_orthology)
Disease	Profound Mental Retardation	RALGDS SYNGAP1 POLR3B CNDP1	3.48e-03	139	131	4	C0020796
Disease	Mental Retardation, Psychosocial	RALGDS SYNGAP1 POLR3B CNDP1	3.48e-03	139	131	4	C0025363
Disease	Mental deficiency	RALGDS SYNGAP1 POLR3B CNDP1	3.48e-03	139	131	4	C0917816
Disease	coagulation factor measurement	F13A1 MCF2L	3.53e-03	20	131	2	EFO_0004634
Disease	Bladder Neoplasm	TRPV1 AS3MT PPP3CC UGT2B7	3.57e-03	140	131	4	C0005695
Disease	Malignant neoplasm of urinary bladder	TRPV1 AS3MT PPP3CC UGT2B7	3.66e-03	141	131	4	C0005684

Protein segments in the cluster

Peptide	Gene	Start	Entry
FDEDAGFLNAIKTFM	ATAD5	1311	Q96QE3
SLRGDIFQKFMESDK	GRK3	156	P35626
FTFAFEKDVEMQKGT	CPSF4L	11	A6NMK7
KEFQKVAFDFAAREM	ACAD8	46	Q9UKU7
FDTMLEIKKAFFALV	PRKAG3	206	Q9UGI9
DMADKLTRENKEFFG	AFF2	1261	P51816
FAVAVKMGATKADFD	GSR	491	P00390
MKFLEKGELANFRFQ	ARFGEF2	1166	Q9Y6D5
RFDGVDAEFKELMFK	DNAH11	1566	Q96DT5
AKVFMGKVDDFLQAL	DNAH11	3241	Q96DT5
MILAVDIFDKFNFTG	CELSR1	2246	Q9NYQ6
FNFVSEEEMAKSKRF	CC2D2B	716	Q6DHV5
FFKSMDQDFGVVKEE	DVL2	56	O14641
MLFDKVKAFSVQLDG	ARRDC2	1	Q8TBH0
FSKQRKDFEGMAFLE	GMCL1	306	Q96IK5
EGKEFADSQKLLFME	RAB17	146	Q9H0T7
LPDFQKDDFKGMFNT	RAD17	166	O75943
VEAFLKAKLNMSFGD	TSPOAP1	106	O95153
DQEMLFKETGFSVKL	PTPN2	131	P17706
IIGFLFLKDDFTMEV	ITPR2	2411	Q14571
KSSDFLEMNFGVLQK	KBTBD3	186	Q8NAB2
EFVGLKKDVDAAFMN	KRT76	286	Q01546
EFVALKKDVDAAFMN	KRT84	266	Q9NSB2
EILKKASFNMEVVFG	MAGEB3	151	O15480
ASFNMEVVFGVDLKK	MAGEB3	156	O15480
SFMKLEKGVQELFDE	KIAA0825	351	Q8IV33
KQMAAFKEGFFELIP	NEDD4	1166	P46934
SDALVLAKMKGFDVF	NMT1	436	P30419
LAKMKGFDVFNALDL	NMT1	441	P30419
QDKKFFQSLDGIMFI	SPINK5	46	Q9NQ38
TAFLERLCFEMKKGF	KIAA1109	836	Q2LD37
KIGMKLQEFFTQQFD	KIAA1109	4571	Q2LD37
MEFTFVQLKKDLDAE	KRT80	181	Q6KB66
KKKAALMFANAEEEF	BCCIP	241	Q9P287
FLSLFFKSKDVMIFN	CALHM2	11	Q9HA72
NKDGKISFEEFVSLM	PLS1	66	Q14651
KALMEEFFRQGDKEA	PDE1B	386	Q01064
IYKEFFSQGDLEKAM	PDE2A	826	O00408
SVGLLDMTKQKEFFD	PDE6A	276	P16499
MILHFAKENDFKAFF	PFKFB3	136	Q16875
DMFGNDDKLIFQEGK	LRBA	1146	P50851
NKFFLTNGEIMTFEK	MBL2	136	P11226
MDFEVENAVLGKDFK	F13A1	521	P00488
KEALTKDMEYFFGEN	HMOX2	106	P30519
FMGEDLNFHERKKFQ	RIBC2	146	Q9H4K1
KQYFEQFGKVDDAML	MSI1	126	O43347
QKLMKYFNEFLDGEL	EXOC5	131	O00471
FIFDSAGKELFSEML	IFT27	61	Q9BW83
NRTLDFKEFMKGLND	CAPSL	56	Q8WWF8
LSNMLEFGFGKFVEK	DNAH3	976	Q8TD57
ELKEFFMSFGNVVEL	G3BP2	346	Q9UN86
FLEVKFGLNMTKNFT	DPY19L4	381	Q7Z388
QTIDFEGFKLFMKTF	DGKB	56	Q9Y6T7
EGFKLFMKTFLEAEL	DGKB	61	Q9Y6T7
GHEKELMFDANFTFK	AS3MT	281	Q9HBK9
LMFDANFTFKEGEIV	AS3MT	286	Q9HBK9
QFTDIKRKDFGIMFL	CERS6	196	Q6ZMG9
FMKKLNIEEFEFSQS	BLMH	86	Q13867
AEQFTLMDAELFKKV	RALGDS	391	Q12967
LSDIAFKFNRDDFKM	MCF2L	176	O15068
KKDILFGNMAEIYEF	MCF2	541	P10911
ILNMLKDFLGEEKFQ	ERAP2	461	Q6P179
KTMDGKADVSFVLFF	CMPK1	106	P30085
FLLKFQGMKLTSEEF	CALB2	186	P22676
DAKKGFIRLDMSEFQ	CLPB	401	Q9H078
ANLGFMDIDLNKFKE	GRIA1	231	P42261
MFDERIFTGNKFTKD	GTF2IRD1	426	Q9UHL9
GFFMKDAIKKFVVTQ	ZMPSTE24	161	O75844
SFFGFENALEKIAMK	SEC14L5	136	O43304
GGDALKFSEMFQKDL	SALL3	1186	Q9BXA9
FNLKDFPDFSMDLKD	CFAP47	1091	Q6ZTR5
FGADIGMEKFFNIKC	MTHFD1	671	P11586
QGEKFTSVKEDFMLL	CNTD1	241	Q8N815
EEEKNFKAFASLRMA	RPL13	171	P26373
LLQAGELFMEFRKFD	CYP8B1	196	Q9UNU6
FDVLMVKLKGFFQSA	MED20	91	Q9H944
EFSFLKEFSNMVTAK	SERPINI1	86	Q99574
EPKFDFAMKFNALEL	PPARA	356	Q07869
FEINGLDFMFLSEEK	MSH5	461	O43196
LDDNGTMLFFKGEFV	HPX	61	P02790
FEMARTKKACLIFFD	PSMC2	261	P35998
LLTENGMKCFERFFK	USP9X	731	Q93008
MTAFFKLFDDDLIQD	SPDYA	71	Q5MJ70
FKKQFFLQKEGGDSM	SFSWAP	501	Q12872
LGKDQRDFNMIDLKF	POLR1A	851	O95602
FNNIDIEISMFEKGK	SMCHD1	371	A6NHR9
LGELMKFNVDAFKRF	TRPC4AP	586	Q8TEL6
LMCFAGFSFKEKIFI	SLC9B1P1	186	A6NJY1
EAIKFSGFDEKMFLK	RSAD2	331	Q8WXG1
MFKEALKTGFFEFQA	LARS1	816	Q9P2J5
VDIKMKFSNEVFRFA	SAMD9L	211	Q8IVG5
LFFDTGMGKSKFLQD	SAMD9	1016	Q5K651
NITMFQFFSGIEKKL	FAM98A	161	Q8NCA5
NMDFLKAKSEEFRFG	HAUS1	181	Q96CS2
FSKQRKDFEGMAFLE	GMCL2	306	Q8NEA9
ETKFSVKDLNFRMFD	GNAT2	186	P19087
FMEPKFEFAVKFNAL	PPARG	391	P37231
VGDDKAMKVFDVVNF	PPWD1	151	Q96BP3
DKFADFMVKDVKNGE	GARS1	196	P41250
FSKGLSFMRKEDFAE	MICU2	271	Q8IYU8
FQKSFEKEGSDMELL	SMARCAL1	886	Q9NZC9
GFHFMLVLEKQEKYD	SIAH1	186	Q8IUQ4
KFEQGDIKIEKRMFF	RNF216	441	Q9NWF9
KKEAGIDDMFNFETF	SCN3A	1681	Q9NY46
FTLFFSDVLEKKNMI	ARHGAP5	931	Q13017
TLKAFFDFGKDIKDD	PRORP	281	O15091
MGKIDVDKILFFNQE	STRA8	1	Q7Z7C7
SKMTFLFANLKDRDF	TBC1D9B	371	Q66K14
GNIINATFFEEMDKK	ADGRE3	246	Q9BY15
KLEGFKEKYMEFDLN	AIF1	46	P55008
EAFMKENKDGSFLVR	CLNK	321	Q7Z7G1
LFMVAFQLFDKAGKG	SLC25A13	91	Q9UJS0
EGTKLFAAFFLEMAQ	CNDP1	491	Q96KN2
MAQKGQLSDDEKFLF	MYH11	1	P35749
DIHGQFFDLMKLFEV	PPP3CC	86	P48454
DTAQFEFILKEMFKQ	WASHC5	416	Q12768
SKEDFLGFMNEFLEL	SYNGAP1	641	Q96PV0
FLIMNFLEGKDASAF	PXMP2	126	Q9NR77
LELFKFTIGMGDLEF	TRPV1	636	Q8NER1
GKKARTFDLEAMFEQ	WDR70	31	Q9NW82
NLFFKIKARDSMDFG	RNF175	166	Q8N4F7
KAEKDEMVGANFFLT	SNX18	396	Q96RF0
DKMTFFSDGELVFKD	SRL	356	Q86TD4
LEKMKASGFDFSQVL	XYLB	76	O75191
FLKFMGKTNEAEELF	TTC41P	826	Q6P2S7
MKGNEEFSKERFDIA	TTC3	236	P53804
LLFEDLFKKFNSEMK	POLR3B	371	Q9NW08
FGMIFLELNFKGAEE	TAAR1	156	Q96RJ0
NGEEMTLKQFLDYFK	UBA1	966	P22314
TNKDFRKDAGFLEMK	SLF1	221	Q9BQI6
KNNDGRIDFDEFLKM	TNNC2	141	P02585
QMGFRLEAEFEKNFK	SP140	841	Q13342
FLIEGMDKNAFEKKY	UGGT2	831	Q9NYU1
DTEGLAQMFQVFKKF	ZSWIM1	121	Q9BR11
VKVFNQEGEFMLKFG	TRIM2	646	Q9C040
FMKKVQESRFDVIFA	UGT2B7	136	P16662
EFLFSKKDKELGDVF	TRANK1	2446	O15050
FSMDDIEKVFKGRFK	SEMA6D	331	Q8NFY4
GVLFFFTNIKDLFMK	TRPV4	521	Q9HBA0
IRLFEKGMKFFADDT	UFL1	551	O94874
KGMKFFADDTQAALT	UFL1	556	O94874
RAKDGFLEKLNSMEF	VPS54	621	Q9P1Q0
TLLGFKEDFQMDVFK	MYO5C	311	Q9NQX4